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Mutation Information
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Mutation Site
|
A105T |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
CA |
|
Relevant Drug
|
IFN-beta |
Literature Information
|
PubMed PMID
|
31511380
|
|
Published Year
|
2019 |
|
Journal
|
Journal of virology |
|
Title
|
Multiple Pathways To Avoid Beta Interferon Sensitivity of HIV-1 by Mutations in Capsid. |
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Author
|
Sultana T,Mamede JI,Saito A,Ode H,Nohata K,Cohen R,Nakayama EE,Iwatani Y,Yamashita M,Hope TJ,Shioda T |
|
Evidence
|
Previous studies demonstrated that the impaired infectivity of CsA-dependent CA mutants, including those with the A92E and G94D mutations, in certain cell types was rescued by additional CA mutations, such as P90A and A105T.
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HIV Mutation Detail Information