HPV Mutation Detail Information

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Mutation Information
Mutation Site A105T
Mutation Type Amino acid level
Gene/Protein/Region Type E2
Genotype/Subtype HPV16
Viral Reference AB818688
Country Japan
Literature Information
PubMed PMID 30995759
Disease Cervical intraepithelial neoplasia; Cervical carcinoma
Published Year 2019
Journal Viruses
Title Whole-Genome Analysis of Human Papillomavirus Type 16 Prevalent in Japanese Women with or without Cervical Lesions.
Author Hirose Y,Onuki M,Tenjimbayashi Y,Yamaguchi-Naka M,Mori S,Tasaka N,Satoh T,Morisada T,Iwata T,Kiyono T,Mimura T,Sekizawa A,Matsumoto K,Kukimoto I
Evidence Out of the five SNPs, three led to amino acid changes of the viral proteins as follows: Leu to Phe at amino acid position 28 in the E7 protein, Ala to Thr at position 105 in the E2 protein, and Ser/Pro/Ala to Asp/Asn at position 269 in the L2 protein.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation