HPV Mutation Detail Information

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Mutation Information

Mutation Site	79_83del
Mutation Type	Amino acid level
Gene/Protein/Region Type	E7
Genotype/Subtype	HPV16

Literature Information

PubMed PMID	12239337
Published Year	2002
Journal	Journal of virology
Title	Inactivation of both the retinoblastoma tumor suppressor and p21 by the human papillomavirus type 16 E7 oncoprotein is necessary to inhibit cell cycle arrest in human epithelial cells.
Author	Helt AM,Funk JO,Galloway DA
Evidence	The E7 C-terminal mutant proteins E7 CVQ68-70AAA and E7 Delta79-83 (deletion of positions 79 through 83) were further tested in several models of cell cycle arrest associated with elevated levels of p21.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation