Mutation Information
Mutation Site
|
69_bp del |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
LMP1 |
Literature Information
PubMed PMID
|
24886620
|
Published Year
|
2014 |
Journal
|
Virology journal |
Title
|
Difference in cytokine production and cell cycle progression induced by Epstein-Barr virus Lmp1 deletion variants in Kmh2, a Hodgkin lymphoma cell line. |
Author
|
Sueur C,Lupo J,Mas P,Morand P,Boyer V |
Evidence
|
EBV-encoded latent membrane protein 1 (LMP1) is a well-known oncogenic protein and two C-terminal deletion variants, del30-LMP1 and del69-LMP1, have been described in animal models to be more tumorigenic than the wild-type form.
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