|
Mutation Information
|
Mutation Site
|
42-110 DEL |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PreS1 |
|
Amino acid_Mutation
|
2971-3177 DEL |
|
Country
|
china |
Literature Information
|
PubMed PMID
|
32840739
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2020 |
|
Journal
|
Virus genes |
|
Title
|
An antiviral drug-resistant mutant of hepatitis B virus with high replication capacity in association with a large in-frame deletion in the preS1 region of viral surface gene. |
|
Author
|
Wang T,Qin Y,Zhang J,Li X,Tong S,Zhao W,Zhang J |
|
Evidence
|
They also harbored a 207nt deletion covering nt 2971–3177, which led to removal of 69 residues (42th–110th) in the preS1 domain of L protein as well as the spacer of P protein (Fig. 1).
|
|
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HBV Mutation Detail Information