HBV Mutation Detail Information

> 2447_489 DEL1256 Search Result

Mutation Information

Mutation Site	2447_489 DEL1256
Mutation Type	Nucleotide level
Gene/Protein/Region Type	PreS1
Country	China

Literature Information

PubMed PMID	21785721
Disease	Chronic hepatitis B
Published Year	2011
Journal	Hepatitis research and treatment
Title	Evolution of Hepatitis B Virus in a Chronic HBV-Infected Patient over 2 Years.
Author	Shen T,Yan XM,Zhang JP,Wang JL,Zuo RX,Li L,Wang LP
Evidence	Performing alignment showed that over the 2-year period, deletions across overlapping region of polymerase/preS1 (g.2447_489del 1256) or preS1/preS2 (g.3018_3202del 183, and g.3144_56del 126), and pre-S1 initiation codon mutations (g.2846_2865del 18) with or without internal deletions mutations (g.3024_3193del 168) were prevalent (22/26, in 85% of the clones) (Figure 2).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation