HBV Mutation Detail Information

> 12_22DEL Search Result


Mutation Information
Mutation Site 12_22DEL
Mutation Type Amino acid level
Gene/Protein/Region Type PreS2
Amino acid_Mutation 23-55 DEL
Genotype/Subtype C
Relevant Drug lamivudine (LAM)
Country Korea
Literature Information
PubMed PMID 15953865
Disease Chronic hepatitis B
Published Year 2005
Journal Journal of Korean medical science
Title Overlapping gene mutations of hepatitis B virus in a chronic hepatitis B patient with hepatitis B surface antigen loss during lamivudine therapy.
Author Lee SY,Choi MS,Lee D,Lee JH,Koh KC,Paik SW,Yoo BC
Evidence Deletion of nucleotides 23 to 55 (amino acids 12 to 22) was identified in the pre-S2 region.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation