Mutation Information
Mutation Site
|
12-39 del |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Nef |
Literature Information
PubMed PMID
|
33146906
|
Published Year
|
2020 |
Journal
|
The EMBO journal |
Title
|
HIV-1 infection of CD4 T cells impairs antigen-specific B cell function. |
Author
|
Kaw S,Ananth S,Tsopoulidis N,Morath K,Coban BM,Hohenberger R,Bulut OC,Klein F,Stolp B,Fackler OT |
Evidence
|
Consistently, NEF Delta12-39 was also almost entirely defective in preventing actin polymerization in BHEL cells upon IS engagement (Fig 3C and D).
|
|
|