HBV Mutation Detail Information

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Mutation Information
Mutation Site 114INSN
Mutation Type Amino acid level
Gene/Protein/Region Type S
Genotype/Subtype D
Country Italy
Literature Information
PubMed PMID 25418031
Disease HBV infection
Published Year 2015
Journal Hepatology (Baltimore, Md.)
Title Hepatitis B surface antigen genetic elements critical for immune escape correlate with hepatitis B virus reactivation upon immunosuppression.
Author Salpini R,Colagrossi L,Bellocchi MC,Surdo M,Becker C,Alteri C,Aragri M,Ricciardi A,Armenia D,Pollicita M,Di Santo F,Carioti L,Louzoun Y,Mastroianni CM,Lichtner M,Paoloni M,Esposito M,D'Amore C,Marrone A,Marignani M,Sarrecchia C,Sarmati L,Andreoni M,Angelico M,Verheyen J,Perno CF,Svicher V
Evidence This decrease was >90% (compared to WT) for four of five glycosylation sites analyzed (98.5% for T115N, 94.1% for ins115N,92% for T123N, and 90.2% for T117N1+ins114N) by using the Bio-Rad assay and for three of five glycosylation sites (99.9% for T115N, 94.7% for ins115N, and 99.4% for T123N) by using the Architect assay (Fig. 3).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation