Mutation Information
Mutation Site
|
114INSN |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
S |
Genotype/Subtype
|
D |
Country
|
Italy |
Literature Information
PubMed PMID
|
25418031
|
Disease
|
HBV infection
|
Published Year
|
2015 |
Journal
|
Hepatology (Baltimore, Md.) |
Title
|
Hepatitis B surface antigen genetic elements critical for immune escape correlate with hepatitis B virus reactivation upon immunosuppression. |
Author
|
Salpini R,Colagrossi L,Bellocchi MC,Surdo M,Becker C,Alteri C,Aragri M,Ricciardi A,Armenia D,Pollicita M,Di Santo F,Carioti L,Louzoun Y,Mastroianni CM,Lichtner M,Paoloni M,Esposito M,D'Amore C,Marrone A,Marignani M,Sarrecchia C,Sarmati L,Andreoni M,Angelico M,Verheyen J,Perno CF,Svicher V |
Evidence
|
This decrease was >90% (compared to WT) for four of five glycosylation sites analyzed (98.5% for T115N, 94.1% for ins115N,92% for T123N, and 90.2% for T117N1+ins114N) by using the Bio-Rad assay and for three of five glycosylation sites (99.9% for T115N, 94.7% for ins115N, and 99.4% for T123N) by using the Architect assay (Fig. 3).
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