Primary Site >> Pancreatic Cancer
Gene >> ZEB1
| 1. | |||||||||||
| Journal: | Cancer Res. 2007 Sep 15;67(18):8486-93. | ||||||||||
| Title: | Membrane-bound heparin-binding epidermal growth factor like growth factor regulates E-cadherin expression in pancreatic carcinoma cells. | ||||||||||
| Author: | Wang, Fang|Sloss, Callum|Zhang, Xiaobo|Lee, Sam W|Cusack, James C | ||||||||||
| PMID: | 17875687 | ||||||||||
| 2. | |||||||||||
| Journal: | Cancer Res. 2009 Mar 15;69(6):2400-7. | ||||||||||
| Title: | Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway. | ||||||||||
| Author: | Wang, Zhiwei|Li, Yiwei|Kong, Dejuan|Banerjee, Sanjeev|Ahmad, Aamir|Azmi, Asfar Sohail|Ali, Shadan|Abbruzzese, James L|Gallick, Gary E|Sarkar, Fazlul H | ||||||||||
| PMID: | 19276344 | ||||||||||
| 3. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2009 Mar 13;380(3):614-9. | ||||||||||
| Title: | Troglitazone increases expression of E-cadherin and claudin 4 in human pancreatic cancer cells. | ||||||||||
| Author: | Kumei, Shima|Motomura, Wataru|Yoshizaki, Takayuki|Takakusaki, Kaoru|Okumura, Toshikatsu | ||||||||||
| PMID: | 19285010 | ||||||||||
| 4. | |||||||||||
| Journal: | Int J Oncol. 2009 Jun;34(6):1737-42. | ||||||||||
| Title: | Integrative genomic analyses of ZEB2: Transcriptional regulation of ZEB2 based on SMADs, ETS1, HIF1alpha, POU/OCT, and NF-kappaB. | ||||||||||
| Author: | Katoh, Masuko|Katoh, Masaru | ||||||||||
| PMID: | 19424592 | ||||||||||
| 5. | |||||||||||
| Journal: | Cancer Res. 2009 Jul 15;69(14):5820-8. | ||||||||||
| Title: | Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer. | ||||||||||
| Author: | Arumugam, Thiruvengadam|Ramachandran, Vijaya|Fournier, Keith F|Wang, Huamin|Marquis, Lauren|Abbruzzese, James L|Gallick, Gary E|Logsdon, Craig D|McConkey, David J|Choi, Woonyoung | ||||||||||
| PMID: | 19584296 | ||||||||||
| 6. | |||||||||||
| Journal: | Cancer Res. 2009 Aug 15;69(16):6704-12. | ||||||||||
| Title: | Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells. | ||||||||||
| Author: | Li, Yiwei|VandenBoom, Timothy G 2nd|Kong, Dejuan|Wang, Zhiwei|Ali, Shadan|Philip, Philip A|Sarkar, Fazlul H | ||||||||||
| PMID: | 19654291 | ||||||||||
| 7. | |||||||||||
| Journal: | Curr Mol Med. 2009 Sep;9(7):873-86. | ||||||||||
| Title: | Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation. | ||||||||||
| Author: | Katoh, Y|Katoh, M | ||||||||||
| PMID: | 19860666 | ||||||||||
| 8. | |||||||||||
| Journal: | Nat Cell Biol. 2009 Dec;11(12):1487-95. | ||||||||||
| Title: | The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs. | ||||||||||
| Author: | Wellner, Ulrich|Schubert, Jorg|Burk, Ulrike C|Schmalhofer, Otto|Zhu, Feng|Sonntag, Annika|Waldvogel, Bettina|Vannier, Corinne|Darling, Douglas|zur Hausen, Axel|Brunton, Valerie G|Morton, Jennifer|Sansom, Owen|Schuler, Julia|Stemmler, Marc P|Herzberger, Ch | ||||||||||
| PMID: | 19935649 | ||||||||||
| 9. | |||||||||||
| Journal: | Cancer Biol Ther. 2009 Nov;8(21):2013-24. | ||||||||||
| Title: | A resource for analysis of microRNA expression and function in pancreatic ductal adenocarcinoma cells. | ||||||||||
| Author: | Kent, Oliver A|Mullendore, Michael|Wentzel, Eric A|Lopez-Romero, Pedro|Tan, Aik Choon|Alvarez, Hector|West, Kristen|Ochs, Michael F|Hidalgo, Manuel|Arking, Dan E|Maitra, Anirban|Mendell, Joshua T | ||||||||||
| PMID: | 20037478 | ||||||||||
| 10. | |||||||||||
| Journal: | Cancer Lett. 2010 Sep 28;295(2):214-28. | ||||||||||
| Title: | NF-kappaB promotes epithelial-mesenchymal transition, migration and invasion of pancreatic carcinoma cells. | ||||||||||
| Author: | Maier, Harald J|Schmidt-Strassburger, Uta|Huber, Margit A|Wiedemann, Eva M|Beug, Hartmut|Wirth, Thomas | ||||||||||
| PMID: | 20350779 | ||||||||||
| 11. | |||||||||||
| Journal: | Cancers (Basel). 2010 Aug 18;2(3):1617-28. | ||||||||||
| Title: | ZEB1 in Pancreatic Cancer. | ||||||||||
| Author: | Wellner, Ulrich|Brabletz, Thomas|Keck, Tobias | ||||||||||
| PMID: | 24281177 | ||||||||||
| 12. | |||||||||||
| Journal: | Front Biosci (Elite Ed). 2011 Jan 1;3:515-28. | ||||||||||
| Title: | Sulforaphane synergizes with quercetin to inhibit self-renewal capacity of pancreatic cancer stem cells. | ||||||||||
| Author: | Srivastava, Rakesh K|Tang, Su-Ni|Zhu, Wenyu|Meeker, Daniel|Shankar, Sharmila | ||||||||||
| PMID: | 21196331 | ||||||||||
| 13. | |||||||||||
| Journal: | Cancer Res. 2011 Mar 15;71(6):2328-38. | ||||||||||
| Title: | DCAMKL-1 regulates epithelial-mesenchymal transition in human pancreatic cells through a miR-200a-dependent mechanism. | ||||||||||
| Author: | Sureban, Sripathi M|May, Randal|Lightfoot, Stan A|Hoskins, Aimee B|Lerner, Megan|Brackett, Daniel J|Postier, Russell G|Ramanujam, Rama|Mohammed, Altaf|Rao, Chinthalapally V|Wyche, James H|Anant, Shrikant|Houchen, Courtney W | ||||||||||
| PMID: | 21285251 | ||||||||||
| 14. | |||||||||||
| Journal: | PLoS One. 2011 Jan 31;6(1):e16530. | ||||||||||
| Title: | Resveratrol inhibits pancreatic cancer stem cell characteristics in human and KrasG12D transgenic mice by inhibiting pluripotency maintaining factors and epithelial-mesenchymal transition. | ||||||||||
| Author: | Shankar, Sharmila|Nall, Dara|Tang, Su-Ni|Meeker, Daniel|Passarini, Jenna|Sharma, Jay|Srivastava, Rakesh K | ||||||||||
| PMID: | 21304978 | ||||||||||
| 15. | |||||||||||
| Journal: | Cancer Lett. 2011 Aug 1;307(1):26-36. | ||||||||||
| Title: | Notch-1 induces epithelial-mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells. | ||||||||||
| Author: | Bao, Bin|Wang, Zhiwei|Ali, Shadan|Kong, Dejuan|Li, Yiwei|Ahmad, Aamir|Banerjee, Sanjeev|Azmi, Asfar S|Miele, Lucio|Sarkar, Fazlul H | ||||||||||
| PMID: | 21463919 | ||||||||||
| 16. | |||||||||||
| Journal: | J Cell Biochem. 2011 Sep;112(9):2296-306. | ||||||||||
| Title: | Over-expression of FoxM1 leads to epithelial-mesenchymal transition and cancer stem cell phenotype in pancreatic cancer cells. | ||||||||||
| Author: | Bao, Bin|Wang, Zhiwei|Ali, Shadan|Kong, Dejuan|Banerjee, Sanjeev|Ahmad, Aamir|Li, Yiwei|Azmi, Asfar S|Miele, Lucio|Sarkar, Fazlul H | ||||||||||
| PMID: | 21503965 | ||||||||||
| 17. | |||||||||||
| Journal: | PLoS One. 2011;6(8):e24099. | ||||||||||
| Title: | Targeting epigenetic regulation of miR-34a for treatment of pancreatic cancer by inhibition of pancreatic cancer stem cells. | ||||||||||
| Author: | Nalls, Dara|Tang, Su-Ni|Rodova, Marianna|Srivastava, Rakesh K|Shankar, Sharmila | ||||||||||
| PMID: | 21909380 | ||||||||||
| 18. | |||||||||||
| Journal: | Int J Cancer. 2012 Jul 1;131(1):30-40. | ||||||||||
| Title: | Inhibition of sonic hedgehog pathway and pluripotency maintaining factors regulate human pancreatic cancer stem cell characteristics. | ||||||||||
| Author: | Tang, Su-Ni|Fu, Junsheng|Nall, Dara|Rodova, Mariana|Shankar, Sharmila|Srivastava, Rakesh K | ||||||||||
| PMID: | 21796625 | ||||||||||
| 19. | |||||||||||
| Journal: | Gut. 2012 Mar;61(3):329-30. | ||||||||||
| Title: | A ZEB1-HDAC pathway enters the epithelial to mesenchymal transition world in pancreatic cancer. | ||||||||||
| Author: | Schneider, Gunter|Kramer, Oliver H|Saur, Dieter | ||||||||||
| PMID: | 22147511 | ||||||||||
| 20. | |||||||||||
| Journal: | Gut. 2012 Mar;61(3):439-48. | ||||||||||
| Title: | Recruitment of histone deacetylases HDAC1 and HDAC2 by the transcriptional repressor ZEB1 downregulates E-cadherin expression in pancreatic cancer. | ||||||||||
| Author: | Aghdassi, Ali|Sendler, Matthias|Guenther, Annett|Mayerle, Julia|Behn, Claas-Olsen|Heidecke, Claus-Dieter|Friess, Helmut|Buchler, Markus|Evert, Matthias|Lerch, Markus M|Weiss, Frank Ulrich | ||||||||||
| PMID: | 22147512 | ||||||||||
| 21. | |||||||||||
| Journal: | J Surg Oncol. 2012 Jun 1;105(7):655-61. | ||||||||||
| Title: | Epithelial-mesenchymal transition and mesenchymal-epithelial transition via regulation of ZEB-1 and ZEB-2 expression in pancreatic cancer. | ||||||||||
| Author: | Kurahara, Hiroshi|Takao, Sonshin|Maemura, Kosei|Mataki, Yuko|Kuwahata, Taisaku|Maeda, Koki|Ding, Qiang|Sakoda, Masahiko|Iino, Satoshi|Ishigami, Sumiya|Ueno, Shinichi|Shinchi, Hiroyuki|Natsugoe, Shoji | ||||||||||
| PMID: | 22213144 | ||||||||||
| 22. | |||||||||||
| Journal: | Carcinogenesis. 2012 Oct;33(10):1953-64. | ||||||||||
| Title: | MUC4 potentiates invasion and metastasis of pancreatic cancer cells through stabilization of fibroblast growth factor receptor 1. | ||||||||||
| Author: | Rachagani, Satyanarayana|Macha, Muzafar A|Ponnusamy, Moorthy P|Haridas, Dhanya|Kaur, Sukhwinder|Jain, Maneesh|Batra, Surinder K | ||||||||||
| PMID: | 22791819 | ||||||||||
| 23. | |||||||||||
| Journal: | PLoS One. 2012;7(9):e46391. | ||||||||||
| Title: | Hypoxia induces EMT in low and highly aggressive pancreatic tumor cells but only cells with cancer stem cell characteristics acquire pronounced migratory potential. | ||||||||||
| Author: | Salnikov, Alexei V|Liu, Li|Platen, Mitja|Gladkich, Jury|Salnikova, Olga|Ryschich, Eduard|Mattern, Jurgen|Moldenhauer, Gerhard|Werner, Jens|Schemmer, Peter|Buchler, Markus W|Herr, Ingrid | ||||||||||
| PMID: | 23050024 | ||||||||||
| 24. | |||||||||||
| Journal: | Clin Dev Immunol. 2012;2012:720768. | ||||||||||
| Title: | Epithelial-to-mesenchymal transition in pancreatic ductal adenocarcinoma and pancreatic tumor cell lines: the role of neutrophils and neutrophil-derived elastase. | ||||||||||
| Author: | Grosse-Steffen, Thomas|Giese, Thomas|Giese, Nathalia|Longerich, Thomas|Schirmacher, Peter|Hansch, G Maria|Gaida, Matthias M | ||||||||||
| PMID: | 23227088 | ||||||||||
| 25. | |||||||||||
| Journal: | Int J Cancer. 2013 Feb 15;132(4):785-94. | ||||||||||
| Title: | Macrophage migration inhibitory factor induces epithelial to mesenchymal transition, enhances tumor aggressiveness and predicts clinical outcome in resected pancreatic ductal adenocarcinoma. | ||||||||||
| Author: | Funamizu, Naotake|Hu, Chaoxin|Lacy, Curtis|Schetter, Aaron|Zhang, Geng|He, Peijun|Gaedcke, Jochen|Ghadimi, Michael B|Ried, Thomas|Yfantis, Harris G|Lee, Dong H|Subleski, Jeffrey|Chan, Tim|Weiss, Jonathan M|Back, Timothy C|Yanaga, Katsuhiko|Hanna, Nader|Al | ||||||||||
| PMID: | 22821831 | ||||||||||
| 26. | |||||||||||
| Journal: | Mol Cell Biochem. 2013 Jan;372(1-2):83-94. | ||||||||||
| Title: | EGCG inhibits growth of human pancreatic tumors orthotopically implanted in Balb C nude mice through modulation of FKHRL1/FOXO3a and neuropilin. | ||||||||||
| Author: | Shankar, Sharmila|Marsh, Luke|Srivastava, Rakesh K | ||||||||||
| PMID: | 22971992 | ||||||||||
| 27. | |||||||||||
| Journal: | Mol Cell Biochem. 2013 Jan;373(1-2):217-27. | ||||||||||
| Title: | Sulforaphane regulates self-renewal of pancreatic cancer stem cells through the modulation of Sonic hedgehog-GLI pathway. | ||||||||||
| Author: | Li, Shih-Hui|Fu, Junsheng|Watkins, Dara Nall|Srivastava, Rakesh K|Shankar, Sharmila | ||||||||||
| PMID: | 23129257 | ||||||||||
| 28. | |||||||||||
| Journal: | Cancer Lett. 2013 Mar 1;330(1):22-32. | ||||||||||
| Title: | GANT-61 inhibits pancreatic cancer stem cell growth in vitro and in NOD/SCID/IL2R gamma null mice xenograft. | ||||||||||
| Author: | Fu, Junsheng|Rodova, Mariana|Roy, Sanjit K|Sharma, Jay|Singh, Karan P|Srivastava, Rakesh K|Shankar, Sharmila | ||||||||||
| PMID: | 23200667 | ||||||||||
| 29. | |||||||||||
| Journal: | Evid Based Complement Alternat Med. 2013;2013:270906. | ||||||||||
| Title: | Caffeic Acid phenethyl ester inhibits epithelial-mesenchymal transition of human pancreatic cancer cells. | ||||||||||
| Author: | Chen, Ming-Jen|Shih, Shou-Chuan|Wang, Horng-Yuan|Lin, Ching-Chung|Liu, Chia-Yuan|Wang, Tsang-En|Chu, Cheng-Hsin|Chen, Yu-Jen | ||||||||||
| PMID: | 23662124 | ||||||||||
| 30. | |||||||||||
| Journal: | Cancer Res. 2013 Sep 1;73(17):5416-25. | ||||||||||
| Title: | FOXL1, a novel candidate tumor suppressor, inhibits tumor aggressiveness and predicts outcome in human pancreatic cancer. | ||||||||||
| Author: | Zhang, Geng|He, Peijun|Gaedcke, Jochen|Ghadimi, B Michael|Ried, Thomas|Yfantis, Harris G|Lee, Dong H|Hanna, Nader|Alexander, H Richard|Hussain, S Perwez | ||||||||||
| PMID: | 23801748 | ||||||||||
| 31. | |||||||||||
| Journal: | Mol Cancer Ther. 2013 Oct;12(10):2213-25. | ||||||||||
| Title: | Subtype-specific MEK-PI3 kinase feedback as a therapeutic target in pancreatic adenocarcinoma. | ||||||||||
| Author: | Mirzoeva, Olga K|Collisson, Eric A|Schaefer, Peter M|Hann, Byron|Hom, Yun K|Ko, Andrew H|Korn, W Michael | ||||||||||
| PMID: | 23918833 | ||||||||||
| 32. | |||||||||||
| Journal: | PLoS One. 2013 Sep 9;8(9):e73940. | ||||||||||
| Title: | DCLK1 regulates pluripotency and angiogenic factors via microRNA-dependent mechanisms in pancreatic cancer. | ||||||||||
| Author: | Sureban, Sripathi M|May, Randal|Qu, Dongfeng|Weygant, Nathaniel|Chandrakesan, Parthasarathy|Ali, Naushad|Lightfoot, Stan A|Pantazis, Panayotis|Rao, Chinthalapally V|Postier, Russell G|Houchen, Courtney W | ||||||||||
| PMID: | 24040120 | ||||||||||
| 33. | |||||||||||
| Journal: | PLoS One. 2013 Oct 15;8(10):e73306. | ||||||||||
| Title: | MUC1 regulates expression of multiple microRNAs involved in pancreatic tumor progression, including the miR-200c/141 cluster. | ||||||||||
| Author: | Mohr, Ashley M|Bailey, Jennifer M|Lewallen, Michelle E|Liu, Xiang|Radhakrishnan, Prakash|Yu, Fang|Tapprich, William|Hollingsworth, Michael A | ||||||||||
| PMID: | 24143167 | ||||||||||
| 34. | |||||||||||
| Journal: | Front Biosci (Landmark Ed). 2014 Jan 1;19:113-25. | ||||||||||
| Title: | Embelin suppresses pancreatic cancer growth by modulating tumor immune microenvironment. | ||||||||||
| Author: | Marsh, Justine L|Jackman, Chris P|Tang, Su-Ni|Shankar, Sharmila|Srivastava, Rakesh K | ||||||||||
| PMID: | 24389175 | ||||||||||
| 35. | |||||||||||
| Journal: | Oncol Lett. 2014 Mar;7(3):658-662. | ||||||||||
| Title: | miR-203 inhibits tumor cell migration and invasion via caveolin-1 in pancreatic cancer cells. | ||||||||||
| Author: | Miao, Lifeng|Xiong, Xianze|Lin, Yixin|Cheng, Yao|Lu, Jiong|Zhang, Jie|Cheng, Nansheng | ||||||||||
| PMID: | 24520289 | ||||||||||
| 36. | |||||||||||
| Journal: | BMC Cancer. 2014 Feb 12;14:85. | ||||||||||
| Title: | MiR-200a inhibits epithelial-mesenchymal transition of pancreatic cancer stem cell. | ||||||||||
| Author: | Lu, Yuhua|Lu, Jingjing|Li, Xiaohong|Zhu, Hui|Fan, Xiangjun|Zhu, Shajun|Wang, Yao|Guo, Qingsong|Wang, Lei|Huang, Yan|Zhu, Mingyan|Wang, Zhiwei | ||||||||||
| PMID: | 24521357 | ||||||||||
| 37. | |||||||||||
| Journal: | PLoS One. 2014 Apr 2;9(4):e92161. | ||||||||||
| Title: | Embelin suppresses growth of human pancreatic cancer xenografts, and pancreatic cancer cells isolated from KrasG12D mice by inhibiting Akt and Sonic hedgehog pathways. | ||||||||||
| Author: | Huang, Minzhao|Tang, Su-Ni|Upadhyay, Ghanshyam|Marsh, Justin L|Jackman, Christopher P|Shankar, Sharmila|Srivastava, Rakesh K | ||||||||||
| PMID: | 24694877 | ||||||||||
| 38. | |||||||||||
| Journal: | Cancer Lett. 2014 Aug 28;351(1):151-61. | ||||||||||
| Title: | XMD8-92 inhibits pancreatic tumor xenograft growth via a DCLK1-dependent mechanism. | ||||||||||
| Author: | Sureban, Sripathi M|May, Randal|Weygant, Nathaniel|Qu, Dongfeng|Chandrakesan, Parthasarathy|Bannerman-Menson, Eddie|Ali, Naushad|Pantazis, Panayotis|Westphalen, Christoph B|Wang, Timothy C|Houchen, Courtney W | ||||||||||
| PMID: | 24880079 | ||||||||||
| 39. | |||||||||||
| Journal: | Surgery. 2014 Jul;156(1):97-108. | ||||||||||
| Title: | Prognostic significance of Zinc finger E-box binding homeobox 1 (ZEB1) expression in cancer cells and cancer-associated fibroblasts in pancreatic head cancer. | ||||||||||
| Author: | Bronsert, Peter|Kohler, Ilona|Timme, Sylvia|Kiefer, Selina|Werner, Martin|Schilling, Oliver|Vashist, Yogesh|Makowiec, Frank|Brabletz, Thomas|Hopt, Ulrich T|Bausch, Dirk|Kulemann, Birte|Keck, Tobias|Wellner, Ulrich F | ||||||||||
| PMID: | 24929761 | ||||||||||
| 40. | |||||||||||
| Journal: | World J Gastroenterol. 2014 Jul 14;20(26):8545-57. | ||||||||||
| Title: | Clobenpropit enhances anti-tumor effect of gemcitabine in pancreatic cancer. | ||||||||||
| Author: | Paik, Woo Hyun|Ryu, Ji Kon|Jeong, Kyoung-Sin|Park, Jin Myung|Song, Byeong Jun|Lee, Sang Hyub|Kim, Yong-Tae|Yoon, Yong Bum | ||||||||||
| PMID: | 25024609 | ||||||||||
| 41. | |||||||||||
| Journal: | Oncol Rep. 2014 Oct;32(4):1451-8. | ||||||||||
| Title: | USP22 promotes epithelial-mesenchymal transition via the FAK pathway in pancreatic cancer cells. | ||||||||||
| Author: | Ning, Zhen|Wang, Aman|Liang, Jinxiao|Xie, Yunpeng|Liu, Jiwei|Yan, Qiu|Wang, Zhongyu | ||||||||||
| PMID: | 25070659 | ||||||||||
| 42. | |||||||||||
| Journal: | J Pathol. 2014 Nov;234(3):410-22. | ||||||||||
| Title: | Cancer cell invasion and EMT marker expression: a three-dimensional study of the human cancer-host interface. | ||||||||||
| Author: | Bronsert, P|Enderle-Ammour, K|Bader, M|Timme, S|Kuehs, M|Csanadi, A|Kayser, G|Kohler, I|Bausch, D|Hoeppner, J|Hopt, U T|Keck, T|Stickeler, E|Passlick, B|Schilling, O|Reiss, C P|Vashist, Y|Brabletz, T|Berger, J|Lotz, J|Olesch, J|Werner, M|Wellner, U F | ||||||||||
| PMID: | 25081610 | ||||||||||
| 43. | |||||||||||
| Journal: | J Clin Biochem Nutr. 2014 Jul;55(1):56-61. | ||||||||||
| Title: | The inhibitory effect of heat treatment against epithelial-mesenchymal transition (EMT) in human pancreatic adenocarcinoma cell lines. | ||||||||||
| Author: | Kimura-Tsuchiya, Reiko|Ishikawa, Takeshi|Kokura, Satoshi|Mizushima, Katsura|Adachi, Satoko|Okajima, Manabu|Matsuyama, Tatsuzo|Okayama, Tetsuya|Sakamoto, Naoyuki|Katada, Kazuhiro|Kamada, Kazuhiro|Uchiyama, Kazuhiko|Handa, Osamu|Takagi, Tomohisa|Yagi, Nobua | ||||||||||
| PMID: | 25120280 | ||||||||||
| 44. | |||||||||||
| Journal: | PLoS One. 2014 Aug 29;9(8):e105245. | ||||||||||
| Title: | Down-regulation of 5-HT1B and 5-HT1D receptors inhibits proliferation, clonogenicity and invasion of human pancreatic cancer cells. | ||||||||||
| Author: | Gurbuz, Nilgun|Ashour, Ahmed A|Alpay, S Neslihan|Ozpolat, Bulent | ||||||||||
| PMID: | 25170871 | ||||||||||
| 45. | |||||||||||
| Journal: | J Cell Mol Med. 2014 Nov;18(11):2235-51. | ||||||||||
| Title: | Elongation factor-2 kinase regulates TG2/beta1 integrin/Src/uPAR pathway and epithelial-mesenchymal transition mediating pancreatic cancer cells invasion. | ||||||||||
| Author: | Ashour, Ahmed A|Gurbuz, Nilgun|Alpay, Sultan Neslihan|Abdel-Aziz, Abdel-Aziz H|Mansour, Ahmed M|Huo, Longfei|Ozpolat, Bulent | ||||||||||
| PMID: | 25215932 | ||||||||||
| 46. | |||||||||||
| Journal: | PLoS One. 2014 Sep 15;9(9):e107247. | ||||||||||
| Title: | CD166/ALCAM expression is characteristic of tumorigenicity and invasive and migratory activities of pancreatic cancer cells. | ||||||||||
| Author: | Fujiwara, Kenji|Ohuchida, Kenoki|Sada, Masafumi|Horioka, Kohei|Ulrich, Charles D 3rd|Shindo, Koji|Ohtsuka, Takao|Takahata, Shunichi|Mizumoto, Kazuhiro|Oda, Yoshinao|Tanaka, Masao | ||||||||||
| PMID: | 25221999 | ||||||||||
| 47. | |||||||||||
| Journal: | PLoS One. 2014 Sep 30;9(9):e110067. | ||||||||||
| Title: | Down-regulation of 5-HT1B and 5-HT1D receptors inhibits proliferation, clonogenicity and invasion of human pancreatic cancer cells. | ||||||||||
| Author: | Gurbuz, Nilgun|Ashour, Ahmed A|Alpay, S Neslihan|Ozpolat, Bulent | ||||||||||
| PMID: | 25268648 | ||||||||||
| 48. | |||||||||||
| Journal: | Cancer Lett. 2015 Jan 28;356(2 Pt B):613-27. | ||||||||||
| Title: | Mutated K-ras activates CDK8 to stimulate the epithelial-to-mesenchymal transition in pancreatic cancer in part via the Wnt/beta-catenin signaling pathway. | ||||||||||
| Author: | Xu, Wei|Wang, Ziwei|Zhang, Wei|Qian, Kun|Li, Hui|Kong, Dequan|Li, Yuqiang|Tang, Yucheng | ||||||||||
| PMID: | 25305448 | ||||||||||
| 49. | |||||||||||
| Journal: | Tumour Biol. 2015 Apr;36(4):2271-6. | ||||||||||
| Title: | Lung metastasis of pancreatic carcinoma is regulated by TGFbeta signaling. | ||||||||||
| Author: | Song, Liqiang|Wang, Ping|Tian, Yu|Chang, De|Li, Kailong|Fan, Yongna|Shen, Jing|Du, Hongzhen|Mi, Ruifang|Bian, Xiaoxia|Tang, Xianchao | ||||||||||
| PMID: | 25409617 | ||||||||||
| 50. | |||||||||||
| Journal: | Exp Mol Pathol. 2015 Feb;98(1):41-6. | ||||||||||
| Title: | Pancreatic cancer cells express CD44 variant 9 and multidrug resistance protein 1 during mitosis. | ||||||||||
| Author: | Kiuchi, Shizuka|Ikeshita, Shunji|Miyatake, Yukiko|Kasahara, Masanori | ||||||||||
| PMID: | 25481101 | ||||||||||
| 51. | |||||||||||
| Journal: | Nan Fang Yi Ke Da Xue Xue Bao. 2015 Feb;35(2):179-84. | ||||||||||
| Title: | [Effect of MSX2 interference on epithelial-mesenchymal transitions of pancreatic cancer cell line PANC-1]. | ||||||||||
| Author: | Zhang, Dengyong|Ma, Xiang|Wu, Binquan|Cui, Peiyuan|Liu, Huichun|Lu, Zheng | ||||||||||
| PMID: | 25736109 | ||||||||||
| 52. | |||||||||||
| Journal: | EMBO Mol Med. 2015 Jun;7(6):831-47. | ||||||||||
| Title: | ZEB1-associated drug resistance in cancer cells is reversed by the class I HDAC inhibitor mocetinostat. | ||||||||||
| Author: | Meidhof, Simone|Brabletz, Simone|Lehmann, Waltraut|Preca, Bogdan-Tiberius|Mock, Kerstin|Ruh, Manuel|Schuler, Julia|Berthold, Maria|Weber, Anika|Burk, Ulrike|Lubbert, Michael|Puhr, Martin|Culig, Zoran|Wellner, Ulrich|Keck, Tobias|Bronsert, Peter|Kusters, S | ||||||||||
| PMID: | 25872941 | ||||||||||
| 53. | |||||||||||
| Journal: | Br J Cancer. 2015 Jun 9;112(12):1944-50. | ||||||||||
| Title: | Expression of E-cadherin repressors SNAIL, ZEB1 and ZEB2 by tumour and stromal cells influences tumour-budding phenotype and suggests heterogeneity of stromal cells in pancreatic cancer. | ||||||||||
| Author: | Galvan, J A|Zlobec, I|Wartenberg, M|Lugli, A|Gloor, B|Perren, A|Karamitopoulou, E | ||||||||||
| PMID: | 25989272 | ||||||||||
| 54. | |||||||||||
| Journal: | Int J Cancer. 2015 Dec 1;137(11):2566-77. | ||||||||||
| Title: | A self-enforcing CD44s/ZEB1 feedback loop maintains EMT and stemness properties in cancer cells. | ||||||||||
| Author: | Preca, Bogdan-Tiberius|Bajdak, Karolina|Mock, Kerstin|Sundararajan, Vignesh|Pfannstiel, Jessica|Maurer, Jochen|Wellner, Ulrich|Hopt, Ulrich T|Brummer, Tilman|Brabletz, Simone|Brabletz, Thomas|Stemmler, Marc P | ||||||||||
| PMID: | 26077342 | ||||||||||
| 55. | |||||||||||
| Journal: | Minerva Med. 2015 Aug;106(4):193-202. Epub 2015 Jun 17. | ||||||||||
| Title: | MicroRNA-200c overexpression plays an inhibitory role in human pancreatic cancer stem cells by regulating epithelial-mesenchymal transition. | ||||||||||
| Author: | Ma, C|Ding, Y C|Yu, W|Wang, Q|Meng, B|Huang, T | ||||||||||
| PMID: | 26081037 | ||||||||||
| 56. | |||||||||||
| Journal: | Springerplus. 2015 Jun 6;4:245. | ||||||||||
| Title: | Estrogen and tamoxifen up-regulate FXYD3 on breast cancer cells: assessing the differential roles of ER alpha and ZEB1. | ||||||||||
| Author: | Herrmann, Paul|Aronica, Susan M | ||||||||||
| PMID: | 26090296 | ||||||||||
| 57. | |||||||||||
| Journal: | Oncoimmunology. 2015 Jan 22;4(4):e1000083. | ||||||||||
| Title: | CD4(+) T cells potently induce epithelial-mesenchymal-transition in premalignant and malignant pancreatic ductal epithelial cells-novel implications of CD4(+) T cells in pancreatic cancer development. | ||||||||||
| Author: | Goebel, Lisa|Grage-Griebenow, Evelin|Gorys, Artur|Helm, Ole|Genrich, Geeske|Lenk, Lennart|Wesch, Daniela|Ungefroren, Hendrik|Freitag-Wolf, Sandra|Sipos, Bence|Rocken, Christoph|Schafer, Heiner|Sebens, Susanne | ||||||||||
| PMID: | 26137395 | ||||||||||
| 58. | |||||||||||
| Journal: | Nanomedicine. 2015 Nov;11(8):2061-70. | ||||||||||
| Title: | Anthothecol-encapsulated PLGA nanoparticles inhibit pancreatic cancer stem cell growth by modulating sonic hedgehog pathway. | ||||||||||
| Author: | Verma, Raj Kumar|Yu, Wei|Singh, Surya Pratap|Shankar, Sharmila|Srivastava, Rakesh K | ||||||||||
| PMID: | 26199979 | ||||||||||
| 59. | |||||||||||
| Journal: | Oncotarget. 2015 Oct 13;6(31):32039-60. | ||||||||||
| Title: | PI3K/AKT/mTOR and sonic hedgehog pathways cooperate together to inhibit human pancreatic cancer stem cell characteristics and tumor growth. | ||||||||||
| Author: | Sharma, Narinder|Nanta, Rajesh|Sharma, Jay|Gunewardena, Sumedha|Singh, Karan P|Shankar, Sharmila|Srivastava, Rakesh K | ||||||||||
| PMID: | 26451606 | ||||||||||
| 60. | |||||||||||
| Journal: | Oncotarget. 2015 Nov 24;6(37):39661-75. | ||||||||||
| Title: | MiR-652 inhibits acidic microenvironment-induced epithelial-mesenchymal transition of pancreatic cancer cells by targeting ZEB1. | ||||||||||
| Author: | Deng, Shichang|Li, Xiang|Niu, Yi|Zhu, Shuai|Jin, Yan|Deng, Shijiang|Chen, Jingyuan|Liu, Yang|He, Chi|Yin, Tao|Yang, Zhiyong|Tao, Jing|Xiong, Jiongxin|Wu, Heshui|Wang, Chunyou|Zhao, Gang | ||||||||||
| PMID: | 26498682 | ||||||||||
| 61. | |||||||||||
| Journal: | Acta Biochim Biophys Sin (Shanghai). 2015 Dec;47(12):997-1004. | ||||||||||
| Title: | KDM4B promotes epithelial-mesenchymal transition through up-regulation of ZEB1 in pancreatic cancer. | ||||||||||
| Author: | Li, Shuo|Wu, Linlin|Wang, Qingbing|Li, Yingyi|Wang, Xiaolin | ||||||||||
| PMID: | 26511091 | ||||||||||
| 62. | |||||||||||
| Journal: | Nature. 2015 Nov 26;527(7579):525-530. | ||||||||||
| Title: | Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer. | ||||||||||
| Author: | Zheng, Xiaofeng|Carstens, Julienne L|Kim, Jiha|Scheible, Matthew|Kaye, Judith|Sugimoto, Hikaru|Wu, Chia-Chin|LeBleu, Valerie S|Kalluri, Raghu | ||||||||||
| PMID: | 26560028 | ||||||||||
| 63. | |||||||||||
| Journal: | Mol Cancer Res. 2016 Feb;14(2):216-27. | ||||||||||
| Title: | Differential Regulation of ZEB1 and EMT by MAPK-Interacting Protein Kinases (MNK) and eIF4E in Pancreatic Cancer. | ||||||||||
| Author: | Kumar, Krishan|Chow, Christina R|Ebine, Kazumi|Arslan, Ahmet D|Kwok, Benjamin|Bentrem, David J|Eckerdt, Frank D|Platanias, Leonidas C|Munshi, Hidayatullah G | ||||||||||
| PMID: | 26609108 | ||||||||||
| 64. | |||||||||||
| Journal: | Int J Oncol. 2016 Jan;48(1):145-52. | ||||||||||
| Title: | A crucial epithelial to mesenchymal transition regulator, Sox4/Ezh2 axis is closely related to the clinical outcome in pancreatic cancer patients. | ||||||||||
| Author: | Hasegawa, Shinichiro|Nagano, Hiroaki|Konno, Masamitsu|Eguchi, Hidetoshi|Tomokuni, Akira|Tomimaru, Yoshito|Asaoka, Tadafumi|Wada, Hiroshi|Hama, Naoki|Kawamoto, Koichi|Marubashi, Shigeru|Nishida, Naohiro|Koseki, Jun|Mori, Masaki|Doki, Yuichiro|Ishii, Hidesh | ||||||||||
| PMID: | 26648239 | ||||||||||
| 65. | |||||||||||
| Journal: | Cancer Lett. 2016 May 1;374(2):261-71. | ||||||||||
| Title: | LincRNA-ROR promotes invasion, metastasis and tumor growth in pancreatic cancer through activating ZEB1 pathway. | ||||||||||
| Author: | Zhan, Han-Xiang|Wang, Yao|Li, Ce|Xu, Jian-Wei|Zhou, Bin|Zhu, Jian-Kang|Han, Hai-Feng|Wang, Lei|Wang, Yun-Shan|Hu, San-Yuan | ||||||||||
| PMID: | 26898939 | ||||||||||
| 66. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2016 Apr 1;472(2):346-52. | ||||||||||
| Title: | miR-1271 inhibits migration, invasion and epithelial-mesenchymal transition by targeting ZEB1 and TWIST1 in pancreatic cancer cells. | ||||||||||
| Author: | Liu, Huaize|Wang, Han|Liu, Xiaoxiao|Yu, Tingting | ||||||||||
| PMID: | 26940738 | ||||||||||
| 67. | |||||||||||
| Journal: | Mol Pharm. 2016 Jun 6;13(6):1822-32. | ||||||||||
| Title: | Micelle Mixtures for Coadministration of Gemcitabine and GDC-0449 To Treat Pancreatic Cancer. | ||||||||||
| Author: | Karaca, Melek|Dutta, Rinku|Ozsoy, Yildiz|Mahato, Ram I | ||||||||||
| PMID: | 26981724 | ||||||||||
| 68. | |||||||||||
| Journal: | Onco Targets Ther. 2016 Jul 11;9:4225-37. | ||||||||||
| Title: | Interleukin-32alpha inactivates JAK2/STAT3 signaling and reverses interleukin-6-induced epithelial-mesenchymal transition, invasion, and metastasis in pancreatic cancer cells. | ||||||||||
| Author: | Chen, Jingfeng|Wang, Silu|Su, Jiadong|Chu, Guanyu|You, Heyi|Chen, Zongjing|Sun, Hongwei|Chen, Bicheng|Zhou, Mengtao | ||||||||||
| PMID: | 27471397 | ||||||||||
| 69. | |||||||||||
| Journal: | Mol Cell Biol. 2016 Oct 13;36(21):2742-2754. | ||||||||||
| Title: | Suppression of MicroRNA 200 Family Expression by Oncogenic KRAS Activation Promotes Cell Survival and Epithelial-Mesenchymal Transition in KRAS-Driven Cancer. | ||||||||||
| Author: | Zhong, Xiaomin|Zheng, Lan|Shen, Jianfeng|Zhang, Dongmei|Xiong, Minmin|Zhang, Youyou|He, Xinhong|Tanyi, Janos L|Yang, Feng|Montone, Kathleen T|Chen, Xiaojun|Xu, Congjian|Xiang, Andy P|Huang, Qihong|Xu, Xiaowei|Zhang, Lin | ||||||||||
| PMID: | 27550813 | ||||||||||
| 70. | |||||||||||
| Journal: | Sci Rep. 2016 Sep 14;6:32743. | ||||||||||
| Title: | alpha-Mangostin-encapsulated PLGA nanoparticles inhibit pancreatic carcinogenesis by targeting cancer stem cells in human, and transgenic (Kras(G12D), and Kras(G12D)/tp53R270H) mice. | ||||||||||
| Author: | Verma, Raj Kumar|Yu, Wei|Shrivastava, Anju|Shankar, Sharmila|Srivastava, Rakesh K | ||||||||||
| PMID: | 27624879 | ||||||||||
| 71. | |||||||||||
| Journal: | Lab Invest. 2016 Dec;96(12):1268-1278. | ||||||||||
| Title: | Inhibition of NF-kappa B pathway leads to deregulation of epithelial-mesenchymal transition and neural invasion in pancreatic cancer. | ||||||||||
| Author: | Nomura, Alice|Majumder, Kaustav|Giri, Bhuwan|Dauer, Patricia|Dudeja, Vikas|Roy, Sabita|Banerjee, Sulagna|Saluja, Ashok K | ||||||||||
| PMID: | 27775688 | ||||||||||
| 72. | |||||||||||
| Journal: | Int J Oncol. 2017 Jan;50(1):111-120. | ||||||||||
| Title: | Oridonin inhibition and miR200b3p/ZEB1 axis in human pancreatic cancer. | ||||||||||
| Author: | Gui, Zhifang|Luo, Feng|Yang, Yayang|Shen, Can|Li, Shuquan|Xu, Jian | ||||||||||
| PMID: | 27878247 | ||||||||||
| 73. | |||||||||||
| Journal: | Mol Cancer Res. 2017 Apr;15(4):478-488. | ||||||||||
| Title: | Potent EMT and CSC Phenotypes Are Induced By Oncostatin-M in Pancreatic Cancer. | ||||||||||
| Author: | Smigiel, Jacob M|Parameswaran, Neetha|Jackson, Mark W | ||||||||||
| PMID: | 28053127 | ||||||||||
| 74. | |||||||||||
| Journal: | J Hepatobiliary Pancreat Sci. 2017 Mar;24(3):176-184. | ||||||||||
| Title: | Analysis of the origin of anaplastic pancreatic cancer and the mechanism of its dedifferentiation. | ||||||||||
| Author: | Miura, Kotaro|Kimura, Kenjiro|Amano, Ryosuke|Yamazoe, Sadaaki|Ohira, Go|Nishio, Kohei|Kametani, Naoki|Hirakawa, Kosei|Ohira, Masaichi | ||||||||||
| PMID: | 28064441 | ||||||||||
| 75. | |||||||||||
| Journal: | Oncotarget. 2017 Apr 11;8(15):24978-24987. | ||||||||||
| Title: | The mir-675-5p regulates the progression and development of pancreatic cancer via the UBQLN1-ZEB1-mir200 axis. | ||||||||||
| Author: | Wang, Jue|Zhang, Youli|Wei, Hong|Zhang, Xingxing|Wu, Yan|Gong, Aihua|Xia, Yu|Wang, Wenbing|Xu, Min | ||||||||||
| PMID: | 28212565 | ||||||||||
| 76. | |||||||||||
| Journal: | J Pathol. 2017 Jun;242(2):221-233. | ||||||||||
| Title: | Thymidylate synthase is functionally associated with ZEB1 and contributes to the epithelial-to-mesenchymal transition of cancer cells. | ||||||||||
| Author: | Siddiqui, Aarif|Vazakidou, Maria Eleni|Schwab, Annemarie|Napoli, Francesca|Fernandez-Molina, Cristina|Rapa, Ida|Stemmler, Marc P|Volante, Marco|Brabletz, Thomas|Ceppi, Paolo | ||||||||||
| PMID: | 28337746 | ||||||||||
| 77. | |||||||||||
| Journal: | Oncotarget. 2017 Jun 13;8(24):39048-39063. | ||||||||||
| Title: | CBX7 negatively regulates migration and invasion in glioma via Wnt/beta-catenin pathway inactivation. | ||||||||||
| Author: | Bao, Zhongyuan|Xu, Xiupeng|Liu, Yinlong|Chao, Honglu|Lin, Chao|Li, Zheng|You, Yongping|Liu, Ning|Ji, Jing | ||||||||||
| PMID: | 28388562 | ||||||||||
| 78. | |||||||||||
| Journal: | Nat Cell Biol. 2017 May;19(5):518-529. | ||||||||||
| Title: | The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer. | ||||||||||
| Author: | Krebs, Angela M|Mitschke, Julia|Lasierra Losada, Maria|Schmalhofer, Otto|Boerries, Melanie|Busch, Hauke|Boettcher, Martin|Mougiakakos, Dimitrios|Reichardt, Wilfried|Bronsert, Peter|Brunton, Valerie G|Pilarsky, Christian|Winkler, Thomas H|Brabletz, Simone| | ||||||||||
| PMID: | 28414315 | ||||||||||
| 79. | |||||||||||
| Journal: | Oncotarget. 2017 May 9;8(19):31435-31448. | ||||||||||
| Title: | Prognostic significance of ZEB1 and ZEB2 in digestive cancers: a cohort-based analysis and secondary analysis. | ||||||||||
| Author: | Chen, Huihui|Lu, Wei|Huang, Chongjie|Ding, Kefeng|Xia, Dajing|Wu, Yihua|Cai, Mao | ||||||||||
| PMID: | 28416756 | ||||||||||
| 80. | |||||||||||
| Journal: | Nat Cell Biol. 2017 Apr 27;19(5):416-418. | ||||||||||
| Title: | Context-specific roles of EMT programmes in cancer cell dissemination. | ||||||||||
| Author: | Nieto, M Angela | ||||||||||
| PMID: | 28446813 | ||||||||||
| 81. | |||||||||||
| Journal: | Mod Pathol. 2017 Aug;30(8):1116-1125. | ||||||||||
| Title: | MicroRNA dysregulation in the tumor microenvironment influences the phenotype of pancreatic cancer. | ||||||||||
| Author: | Karamitopoulou, Eva|Haemmig, Stefan|Baumgartner, Ulrich|Schlup, Cornelia|Wartenberg, Martin|Vassella, Erik | ||||||||||
| PMID: | 28548126 | ||||||||||
| 82. | |||||||||||
| Journal: | Transl Oncol. 2017 Aug;10(4):578-588. | ||||||||||
| Title: | The Role of Fibroblasts in Pancreatic Cancer: Extracellular Matrix Versus Paracrine Factors. | ||||||||||
| Author: | Bolm, Louisa|Cigolla, Simon|Wittel, Uwe A|Hopt, Ulrich T|Keck, Tobias|Rades, Dirk|Bronsert, Peter|Wellner, Ulrich Friedrich | ||||||||||
| PMID: | 28658650 | ||||||||||
| 83. | |||||||||||
| Journal: | Cell Death Dis. 2017 Jul 13;8(7):e2924. | ||||||||||
| Title: | |||||||||||