Primary Site >> Pancreatic Cancer

Gene >> ZEB1

Journal: Cancer Res. 2007 Sep 15;67(18):8486-93.
Title: Membrane-bound heparin-binding epidermal growth factor like growth factor regulates E-cadherin expression in pancreatic carcinoma cells.
Author: Wang, Fang|Sloss, Callum|Zhang, Xiaobo|Lee, Sam W|Cusack, James C
PMID: 17875687
Journal: Cancer Res. 2009 Mar 15;69(6):2400-7.
Title: Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway.
Author: Wang, Zhiwei|Li, Yiwei|Kong, Dejuan|Banerjee, Sanjeev|Ahmad, Aamir|Azmi, Asfar Sohail|Ali, Shadan|Abbruzzese, James L|Gallick, Gary E|Sarkar, Fazlul H
PMID: 19276344
Journal: Biochem Biophys Res Commun. 2009 Mar 13;380(3):614-9.
Title: Troglitazone increases expression of E-cadherin and claudin 4 in human pancreatic cancer cells.
Author: Kumei, Shima|Motomura, Wataru|Yoshizaki, Takayuki|Takakusaki, Kaoru|Okumura, Toshikatsu
PMID: 19285010
Journal: Int J Oncol. 2009 Jun;34(6):1737-42.
Title: Integrative genomic analyses of ZEB2: Transcriptional regulation of ZEB2 based on SMADs, ETS1, HIF1alpha, POU/OCT, and NF-kappaB.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 19424592
Journal: Cancer Res. 2009 Jul 15;69(14):5820-8.
Title: Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer.
Author: Arumugam, Thiruvengadam|Ramachandran, Vijaya|Fournier, Keith F|Wang, Huamin|Marquis, Lauren|Abbruzzese, James L|Gallick, Gary E|Logsdon, Craig D|McConkey, David J|Choi, Woonyoung
PMID: 19584296
Journal: Cancer Res. 2009 Aug 15;69(16):6704-12.
Title: Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells.
Author: Li, Yiwei|VandenBoom, Timothy G 2nd|Kong, Dejuan|Wang, Zhiwei|Ali, Shadan|Philip, Philip A|Sarkar, Fazlul H
PMID: 19654291
Journal: Curr Mol Med. 2009 Sep;9(7):873-86.
Title: Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation.
Author: Katoh, Y|Katoh, M
PMID: 19860666
Journal: Nat Cell Biol. 2009 Dec;11(12):1487-95.
Title: The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs.
Author: Wellner, Ulrich|Schubert, Jorg|Burk, Ulrike C|Schmalhofer, Otto|Zhu, Feng|Sonntag, Annika|Waldvogel, Bettina|Vannier, Corinne|Darling, Douglas|zur Hausen, Axel|Brunton, Valerie G|Morton, Jennifer|Sansom, Owen|Schuler, Julia|Stemmler, Marc P|Herzberger, Ch
PMID: 19935649
Journal: Cancer Biol Ther. 2009 Nov;8(21):2013-24.
Title: A resource for analysis of microRNA expression and function in pancreatic ductal adenocarcinoma cells.
Author: Kent, Oliver A|Mullendore, Michael|Wentzel, Eric A|Lopez-Romero, Pedro|Tan, Aik Choon|Alvarez, Hector|West, Kristen|Ochs, Michael F|Hidalgo, Manuel|Arking, Dan E|Maitra, Anirban|Mendell, Joshua T
PMID: 20037478
Journal: Cancer Lett. 2010 Sep 28;295(2):214-28.
Title: NF-kappaB promotes epithelial-mesenchymal transition, migration and invasion of pancreatic carcinoma cells.
Author: Maier, Harald J|Schmidt-Strassburger, Uta|Huber, Margit A|Wiedemann, Eva M|Beug, Hartmut|Wirth, Thomas
PMID: 20350779
Journal: Cancers (Basel). 2010 Aug 18;2(3):1617-28.
Title: ZEB1 in Pancreatic Cancer.
Author: Wellner, Ulrich|Brabletz, Thomas|Keck, Tobias
PMID: 24281177
Journal: Front Biosci (Elite Ed). 2011 Jan 1;3:515-28.
Title: Sulforaphane synergizes with quercetin to inhibit self-renewal capacity of pancreatic cancer stem cells.
Author: Srivastava, Rakesh K|Tang, Su-Ni|Zhu, Wenyu|Meeker, Daniel|Shankar, Sharmila
PMID: 21196331
Journal: Cancer Res. 2011 Mar 15;71(6):2328-38.
Title: DCAMKL-1 regulates epithelial-mesenchymal transition in human pancreatic cells through a miR-200a-dependent mechanism.
Author: Sureban, Sripathi M|May, Randal|Lightfoot, Stan A|Hoskins, Aimee B|Lerner, Megan|Brackett, Daniel J|Postier, Russell G|Ramanujam, Rama|Mohammed, Altaf|Rao, Chinthalapally V|Wyche, James H|Anant, Shrikant|Houchen, Courtney W
PMID: 21285251
Journal: PLoS One. 2011 Jan 31;6(1):e16530.
Title: Resveratrol inhibits pancreatic cancer stem cell characteristics in human and KrasG12D transgenic mice by inhibiting pluripotency maintaining factors and epithelial-mesenchymal transition.
Author: Shankar, Sharmila|Nall, Dara|Tang, Su-Ni|Meeker, Daniel|Passarini, Jenna|Sharma, Jay|Srivastava, Rakesh K
PMID: 21304978
Journal: Cancer Lett. 2011 Aug 1;307(1):26-36.
Title: Notch-1 induces epithelial-mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells.
Author: Bao, Bin|Wang, Zhiwei|Ali, Shadan|Kong, Dejuan|Li, Yiwei|Ahmad, Aamir|Banerjee, Sanjeev|Azmi, Asfar S|Miele, Lucio|Sarkar, Fazlul H
PMID: 21463919
Journal: J Cell Biochem. 2011 Sep;112(9):2296-306.
Title: Over-expression of FoxM1 leads to epithelial-mesenchymal transition and cancer stem cell phenotype in pancreatic cancer cells.
Author: Bao, Bin|Wang, Zhiwei|Ali, Shadan|Kong, Dejuan|Banerjee, Sanjeev|Ahmad, Aamir|Li, Yiwei|Azmi, Asfar S|Miele, Lucio|Sarkar, Fazlul H
PMID: 21503965
Journal: PLoS One. 2011;6(8):e24099.
Title: Targeting epigenetic regulation of miR-34a for treatment of pancreatic cancer by inhibition of pancreatic cancer stem cells.
Author: Nalls, Dara|Tang, Su-Ni|Rodova, Marianna|Srivastava, Rakesh K|Shankar, Sharmila
PMID: 21909380
Journal: Int J Cancer. 2012 Jul 1;131(1):30-40.
Title: Inhibition of sonic hedgehog pathway and pluripotency maintaining factors regulate human pancreatic cancer stem cell characteristics.
Author: Tang, Su-Ni|Fu, Junsheng|Nall, Dara|Rodova, Mariana|Shankar, Sharmila|Srivastava, Rakesh K
PMID: 21796625
Journal: Gut. 2012 Mar;61(3):329-30.
Title: A ZEB1-HDAC pathway enters the epithelial to mesenchymal transition world in pancreatic cancer.
Author: Schneider, Gunter|Kramer, Oliver H|Saur, Dieter
PMID: 22147511
Journal: Gut. 2012 Mar;61(3):439-48.
Title: Recruitment of histone deacetylases HDAC1 and HDAC2 by the transcriptional repressor ZEB1 downregulates E-cadherin expression in pancreatic cancer.
Author: Aghdassi, Ali|Sendler, Matthias|Guenther, Annett|Mayerle, Julia|Behn, Claas-Olsen|Heidecke, Claus-Dieter|Friess, Helmut|Buchler, Markus|Evert, Matthias|Lerch, Markus M|Weiss, Frank Ulrich
PMID: 22147512
Journal: J Surg Oncol. 2012 Jun 1;105(7):655-61.
Title: Epithelial-mesenchymal transition and mesenchymal-epithelial transition via regulation of ZEB-1 and ZEB-2 expression in pancreatic cancer.
Author: Kurahara, Hiroshi|Takao, Sonshin|Maemura, Kosei|Mataki, Yuko|Kuwahata, Taisaku|Maeda, Koki|Ding, Qiang|Sakoda, Masahiko|Iino, Satoshi|Ishigami, Sumiya|Ueno, Shinichi|Shinchi, Hiroyuki|Natsugoe, Shoji
PMID: 22213144
Journal: Carcinogenesis. 2012 Oct;33(10):1953-64.
Title: MUC4 potentiates invasion and metastasis of pancreatic cancer cells through stabilization of fibroblast growth factor receptor 1.
Author: Rachagani, Satyanarayana|Macha, Muzafar A|Ponnusamy, Moorthy P|Haridas, Dhanya|Kaur, Sukhwinder|Jain, Maneesh|Batra, Surinder K
PMID: 22791819
Journal: PLoS One. 2012;7(9):e46391.
Title: Hypoxia induces EMT in low and highly aggressive pancreatic tumor cells but only cells with cancer stem cell characteristics acquire pronounced migratory potential.
Author: Salnikov, Alexei V|Liu, Li|Platen, Mitja|Gladkich, Jury|Salnikova, Olga|Ryschich, Eduard|Mattern, Jurgen|Moldenhauer, Gerhard|Werner, Jens|Schemmer, Peter|Buchler, Markus W|Herr, Ingrid
PMID: 23050024
Journal: Clin Dev Immunol. 2012;2012:720768.
Title: Epithelial-to-mesenchymal transition in pancreatic ductal adenocarcinoma and pancreatic tumor cell lines: the role of neutrophils and neutrophil-derived elastase.
Author: Grosse-Steffen, Thomas|Giese, Thomas|Giese, Nathalia|Longerich, Thomas|Schirmacher, Peter|Hansch, G Maria|Gaida, Matthias M
PMID: 23227088
Journal: Int J Cancer. 2013 Feb 15;132(4):785-94.
Title: Macrophage migration inhibitory factor induces epithelial to mesenchymal transition, enhances tumor aggressiveness and predicts clinical outcome in resected pancreatic ductal adenocarcinoma.
Author: Funamizu, Naotake|Hu, Chaoxin|Lacy, Curtis|Schetter, Aaron|Zhang, Geng|He, Peijun|Gaedcke, Jochen|Ghadimi, Michael B|Ried, Thomas|Yfantis, Harris G|Lee, Dong H|Subleski, Jeffrey|Chan, Tim|Weiss, Jonathan M|Back, Timothy C|Yanaga, Katsuhiko|Hanna, Nader|Al
PMID: 22821831
Journal: Mol Cell Biochem. 2013 Jan;372(1-2):83-94.
Title: EGCG inhibits growth of human pancreatic tumors orthotopically implanted in Balb C nude mice through modulation of FKHRL1/FOXO3a and neuropilin.
Author: Shankar, Sharmila|Marsh, Luke|Srivastava, Rakesh K
PMID: 22971992
Journal: Mol Cell Biochem. 2013 Jan;373(1-2):217-27.
Title: Sulforaphane regulates self-renewal of pancreatic cancer stem cells through the modulation of Sonic hedgehog-GLI pathway.
Author: Li, Shih-Hui|Fu, Junsheng|Watkins, Dara Nall|Srivastava, Rakesh K|Shankar, Sharmila
PMID: 23129257
Journal: Cancer Lett. 2013 Mar 1;330(1):22-32.
Title: GANT-61 inhibits pancreatic cancer stem cell growth in vitro and in NOD/SCID/IL2R gamma null mice xenograft.
Author: Fu, Junsheng|Rodova, Mariana|Roy, Sanjit K|Sharma, Jay|Singh, Karan P|Srivastava, Rakesh K|Shankar, Sharmila
PMID: 23200667
Journal: Evid Based Complement Alternat Med. 2013;2013:270906.
Title: Caffeic Acid phenethyl ester inhibits epithelial-mesenchymal transition of human pancreatic cancer cells.
Author: Chen, Ming-Jen|Shih, Shou-Chuan|Wang, Horng-Yuan|Lin, Ching-Chung|Liu, Chia-Yuan|Wang, Tsang-En|Chu, Cheng-Hsin|Chen, Yu-Jen
PMID: 23662124
Journal: Cancer Res. 2013 Sep 1;73(17):5416-25.
Title: FOXL1, a novel candidate tumor suppressor, inhibits tumor aggressiveness and predicts outcome in human pancreatic cancer.
Author: Zhang, Geng|He, Peijun|Gaedcke, Jochen|Ghadimi, B Michael|Ried, Thomas|Yfantis, Harris G|Lee, Dong H|Hanna, Nader|Alexander, H Richard|Hussain, S Perwez
PMID: 23801748
Journal: Mol Cancer Ther. 2013 Oct;12(10):2213-25.
Title: Subtype-specific MEK-PI3 kinase feedback as a therapeutic target in pancreatic adenocarcinoma.
Author: Mirzoeva, Olga K|Collisson, Eric A|Schaefer, Peter M|Hann, Byron|Hom, Yun K|Ko, Andrew H|Korn, W Michael
PMID: 23918833
Journal: PLoS One. 2013 Sep 9;8(9):e73940.
Title: DCLK1 regulates pluripotency and angiogenic factors via microRNA-dependent mechanisms in pancreatic cancer.
Author: Sureban, Sripathi M|May, Randal|Qu, Dongfeng|Weygant, Nathaniel|Chandrakesan, Parthasarathy|Ali, Naushad|Lightfoot, Stan A|Pantazis, Panayotis|Rao, Chinthalapally V|Postier, Russell G|Houchen, Courtney W
PMID: 24040120
Journal: PLoS One. 2013 Oct 15;8(10):e73306.
Title: MUC1 regulates expression of multiple microRNAs involved in pancreatic tumor progression, including the miR-200c/141 cluster.
Author: Mohr, Ashley M|Bailey, Jennifer M|Lewallen, Michelle E|Liu, Xiang|Radhakrishnan, Prakash|Yu, Fang|Tapprich, William|Hollingsworth, Michael A
PMID: 24143167
Journal: Front Biosci (Landmark Ed). 2014 Jan 1;19:113-25.
Title: Embelin suppresses pancreatic cancer growth by modulating tumor immune microenvironment.
Author: Marsh, Justine L|Jackman, Chris P|Tang, Su-Ni|Shankar, Sharmila|Srivastava, Rakesh K
PMID: 24389175
Journal: Oncol Lett. 2014 Mar;7(3):658-662.
Title: miR-203 inhibits tumor cell migration and invasion via caveolin-1 in pancreatic cancer cells.
Author: Miao, Lifeng|Xiong, Xianze|Lin, Yixin|Cheng, Yao|Lu, Jiong|Zhang, Jie|Cheng, Nansheng
PMID: 24520289
Journal: BMC Cancer. 2014 Feb 12;14:85.
Title: MiR-200a inhibits epithelial-mesenchymal transition of pancreatic cancer stem cell.
Author: Lu, Yuhua|Lu, Jingjing|Li, Xiaohong|Zhu, Hui|Fan, Xiangjun|Zhu, Shajun|Wang, Yao|Guo, Qingsong|Wang, Lei|Huang, Yan|Zhu, Mingyan|Wang, Zhiwei
PMID: 24521357
Journal: PLoS One. 2014 Apr 2;9(4):e92161.
Title: Embelin suppresses growth of human pancreatic cancer xenografts, and pancreatic cancer cells isolated from KrasG12D mice by inhibiting Akt and Sonic hedgehog pathways.
Author: Huang, Minzhao|Tang, Su-Ni|Upadhyay, Ghanshyam|Marsh, Justin L|Jackman, Christopher P|Shankar, Sharmila|Srivastava, Rakesh K
PMID: 24694877
Journal: Cancer Lett. 2014 Aug 28;351(1):151-61.
Title: XMD8-92 inhibits pancreatic tumor xenograft growth via a DCLK1-dependent mechanism.
Author: Sureban, Sripathi M|May, Randal|Weygant, Nathaniel|Qu, Dongfeng|Chandrakesan, Parthasarathy|Bannerman-Menson, Eddie|Ali, Naushad|Pantazis, Panayotis|Westphalen, Christoph B|Wang, Timothy C|Houchen, Courtney W
PMID: 24880079
Journal: Surgery. 2014 Jul;156(1):97-108.
Title: Prognostic significance of Zinc finger E-box binding homeobox 1 (ZEB1) expression in cancer cells and cancer-associated fibroblasts in pancreatic head cancer.
Author: Bronsert, Peter|Kohler, Ilona|Timme, Sylvia|Kiefer, Selina|Werner, Martin|Schilling, Oliver|Vashist, Yogesh|Makowiec, Frank|Brabletz, Thomas|Hopt, Ulrich T|Bausch, Dirk|Kulemann, Birte|Keck, Tobias|Wellner, Ulrich F
PMID: 24929761
Journal: World J Gastroenterol. 2014 Jul 14;20(26):8545-57.
Title: Clobenpropit enhances anti-tumor effect of gemcitabine in pancreatic cancer.
Author: Paik, Woo Hyun|Ryu, Ji Kon|Jeong, Kyoung-Sin|Park, Jin Myung|Song, Byeong Jun|Lee, Sang Hyub|Kim, Yong-Tae|Yoon, Yong Bum
PMID: 25024609
Journal: Oncol Rep. 2014 Oct;32(4):1451-8.
Title: USP22 promotes epithelial-mesenchymal transition via the FAK pathway in pancreatic cancer cells.
Author: Ning, Zhen|Wang, Aman|Liang, Jinxiao|Xie, Yunpeng|Liu, Jiwei|Yan, Qiu|Wang, Zhongyu
PMID: 25070659
Journal: J Pathol. 2014 Nov;234(3):410-22.
Title: Cancer cell invasion and EMT marker expression: a three-dimensional study of the human cancer-host interface.
Author: Bronsert, P|Enderle-Ammour, K|Bader, M|Timme, S|Kuehs, M|Csanadi, A|Kayser, G|Kohler, I|Bausch, D|Hoeppner, J|Hopt, U T|Keck, T|Stickeler, E|Passlick, B|Schilling, O|Reiss, C P|Vashist, Y|Brabletz, T|Berger, J|Lotz, J|Olesch, J|Werner, M|Wellner, U F
PMID: 25081610
Journal: J Clin Biochem Nutr. 2014 Jul;55(1):56-61.
Title: The inhibitory effect of heat treatment against epithelial-mesenchymal transition (EMT) in human pancreatic adenocarcinoma cell lines.
Author: Kimura-Tsuchiya, Reiko|Ishikawa, Takeshi|Kokura, Satoshi|Mizushima, Katsura|Adachi, Satoko|Okajima, Manabu|Matsuyama, Tatsuzo|Okayama, Tetsuya|Sakamoto, Naoyuki|Katada, Kazuhiro|Kamada, Kazuhiro|Uchiyama, Kazuhiko|Handa, Osamu|Takagi, Tomohisa|Yagi, Nobua
PMID: 25120280
Journal: PLoS One. 2014 Aug 29;9(8):e105245.
Title: Down-regulation of 5-HT1B and 5-HT1D receptors inhibits proliferation, clonogenicity and invasion of human pancreatic cancer cells.
Author: Gurbuz, Nilgun|Ashour, Ahmed A|Alpay, S Neslihan|Ozpolat, Bulent
PMID: 25170871
Journal: J Cell Mol Med. 2014 Nov;18(11):2235-51.
Title: Elongation factor-2 kinase regulates TG2/beta1 integrin/Src/uPAR pathway and epithelial-mesenchymal transition mediating pancreatic cancer cells invasion.
Author: Ashour, Ahmed A|Gurbuz, Nilgun|Alpay, Sultan Neslihan|Abdel-Aziz, Abdel-Aziz H|Mansour, Ahmed M|Huo, Longfei|Ozpolat, Bulent
PMID: 25215932
Journal: PLoS One. 2014 Sep 15;9(9):e107247.
Title: CD166/ALCAM expression is characteristic of tumorigenicity and invasive and migratory activities of pancreatic cancer cells.
Author: Fujiwara, Kenji|Ohuchida, Kenoki|Sada, Masafumi|Horioka, Kohei|Ulrich, Charles D 3rd|Shindo, Koji|Ohtsuka, Takao|Takahata, Shunichi|Mizumoto, Kazuhiro|Oda, Yoshinao|Tanaka, Masao
PMID: 25221999
Journal: PLoS One. 2014 Sep 30;9(9):e110067.
Title: Down-regulation of 5-HT1B and 5-HT1D receptors inhibits proliferation, clonogenicity and invasion of human pancreatic cancer cells.
Author: Gurbuz, Nilgun|Ashour, Ahmed A|Alpay, S Neslihan|Ozpolat, Bulent
PMID: 25268648
Journal: Cancer Lett. 2015 Jan 28;356(2 Pt B):613-27.
Title: Mutated K-ras activates CDK8 to stimulate the epithelial-to-mesenchymal transition in pancreatic cancer in part via the Wnt/beta-catenin signaling pathway.
Author: Xu, Wei|Wang, Ziwei|Zhang, Wei|Qian, Kun|Li, Hui|Kong, Dequan|Li, Yuqiang|Tang, Yucheng
PMID: 25305448
Journal: Tumour Biol. 2015 Apr;36(4):2271-6.
Title: Lung metastasis of pancreatic carcinoma is regulated by TGFbeta signaling.
Author: Song, Liqiang|Wang, Ping|Tian, Yu|Chang, De|Li, Kailong|Fan, Yongna|Shen, Jing|Du, Hongzhen|Mi, Ruifang|Bian, Xiaoxia|Tang, Xianchao
PMID: 25409617
Journal: Exp Mol Pathol. 2015 Feb;98(1):41-6.
Title: Pancreatic cancer cells express CD44 variant 9 and multidrug resistance protein 1 during mitosis.
Author: Kiuchi, Shizuka|Ikeshita, Shunji|Miyatake, Yukiko|Kasahara, Masanori
PMID: 25481101
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2015 Feb;35(2):179-84.
Title: [Effect of MSX2 interference on epithelial-mesenchymal transitions of pancreatic cancer cell line PANC-1].
Author: Zhang, Dengyong|Ma, Xiang|Wu, Binquan|Cui, Peiyuan|Liu, Huichun|Lu, Zheng
PMID: 25736109
Journal: EMBO Mol Med. 2015 Jun;7(6):831-47.
Title: ZEB1-associated drug resistance in cancer cells is reversed by the class I HDAC inhibitor mocetinostat.
Author: Meidhof, Simone|Brabletz, Simone|Lehmann, Waltraut|Preca, Bogdan-Tiberius|Mock, Kerstin|Ruh, Manuel|Schuler, Julia|Berthold, Maria|Weber, Anika|Burk, Ulrike|Lubbert, Michael|Puhr, Martin|Culig, Zoran|Wellner, Ulrich|Keck, Tobias|Bronsert, Peter|Kusters, S
PMID: 25872941
Journal: Br J Cancer. 2015 Jun 9;112(12):1944-50.
Title: Expression of E-cadherin repressors SNAIL, ZEB1 and ZEB2 by tumour and stromal cells influences tumour-budding phenotype and suggests heterogeneity of stromal cells in pancreatic cancer.
Author: Galvan, J A|Zlobec, I|Wartenberg, M|Lugli, A|Gloor, B|Perren, A|Karamitopoulou, E
PMID: 25989272
Journal: Int J Cancer. 2015 Dec 1;137(11):2566-77.
Title: A self-enforcing CD44s/ZEB1 feedback loop maintains EMT and stemness properties in cancer cells.
Author: Preca, Bogdan-Tiberius|Bajdak, Karolina|Mock, Kerstin|Sundararajan, Vignesh|Pfannstiel, Jessica|Maurer, Jochen|Wellner, Ulrich|Hopt, Ulrich T|Brummer, Tilman|Brabletz, Simone|Brabletz, Thomas|Stemmler, Marc P
PMID: 26077342
Journal: Minerva Med. 2015 Aug;106(4):193-202. Epub 2015 Jun 17.
Title: MicroRNA-200c overexpression plays an inhibitory role in human pancreatic cancer stem cells by regulating epithelial-mesenchymal transition.
Author: Ma, C|Ding, Y C|Yu, W|Wang, Q|Meng, B|Huang, T
PMID: 26081037
Journal: Springerplus. 2015 Jun 6;4:245.
Title: Estrogen and tamoxifen up-regulate FXYD3 on breast cancer cells: assessing the differential roles of ER alpha and ZEB1.
Author: Herrmann, Paul|Aronica, Susan M
PMID: 26090296
Journal: Oncoimmunology. 2015 Jan 22;4(4):e1000083.
Title: CD4(+) T cells potently induce epithelial-mesenchymal-transition in premalignant and malignant pancreatic ductal epithelial cells-novel implications of CD4(+) T cells in pancreatic cancer development.
Author: Goebel, Lisa|Grage-Griebenow, Evelin|Gorys, Artur|Helm, Ole|Genrich, Geeske|Lenk, Lennart|Wesch, Daniela|Ungefroren, Hendrik|Freitag-Wolf, Sandra|Sipos, Bence|Rocken, Christoph|Schafer, Heiner|Sebens, Susanne
PMID: 26137395
Journal: Nanomedicine. 2015 Nov;11(8):2061-70.
Title: Anthothecol-encapsulated PLGA nanoparticles inhibit pancreatic cancer stem cell growth by modulating sonic hedgehog pathway.
Author: Verma, Raj Kumar|Yu, Wei|Singh, Surya Pratap|Shankar, Sharmila|Srivastava, Rakesh K
PMID: 26199979
Journal: Oncotarget. 2015 Oct 13;6(31):32039-60.
Title: PI3K/AKT/mTOR and sonic hedgehog pathways cooperate together to inhibit human pancreatic cancer stem cell characteristics and tumor growth.
Author: Sharma, Narinder|Nanta, Rajesh|Sharma, Jay|Gunewardena, Sumedha|Singh, Karan P|Shankar, Sharmila|Srivastava, Rakesh K
PMID: 26451606
Journal: Oncotarget. 2015 Nov 24;6(37):39661-75.
Title: MiR-652 inhibits acidic microenvironment-induced epithelial-mesenchymal transition of pancreatic cancer cells by targeting ZEB1.
Author: Deng, Shichang|Li, Xiang|Niu, Yi|Zhu, Shuai|Jin, Yan|Deng, Shijiang|Chen, Jingyuan|Liu, Yang|He, Chi|Yin, Tao|Yang, Zhiyong|Tao, Jing|Xiong, Jiongxin|Wu, Heshui|Wang, Chunyou|Zhao, Gang
PMID: 26498682
Journal: Acta Biochim Biophys Sin (Shanghai). 2015 Dec;47(12):997-1004.
Title: KDM4B promotes epithelial-mesenchymal transition through up-regulation of ZEB1 in pancreatic cancer.
Author: Li, Shuo|Wu, Linlin|Wang, Qingbing|Li, Yingyi|Wang, Xiaolin
PMID: 26511091
Journal: Nature. 2015 Nov 26;527(7579):525-530.
Title: Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer.
Author: Zheng, Xiaofeng|Carstens, Julienne L|Kim, Jiha|Scheible, Matthew|Kaye, Judith|Sugimoto, Hikaru|Wu, Chia-Chin|LeBleu, Valerie S|Kalluri, Raghu
PMID: 26560028
Journal: Mol Cancer Res. 2016 Feb;14(2):216-27.
Title: Differential Regulation of ZEB1 and EMT by MAPK-Interacting Protein Kinases (MNK) and eIF4E in Pancreatic Cancer.
Author: Kumar, Krishan|Chow, Christina R|Ebine, Kazumi|Arslan, Ahmet D|Kwok, Benjamin|Bentrem, David J|Eckerdt, Frank D|Platanias, Leonidas C|Munshi, Hidayatullah G
PMID: 26609108
Journal: Int J Oncol. 2016 Jan;48(1):145-52.
Title: A crucial epithelial to mesenchymal transition regulator, Sox4/Ezh2 axis is closely related to the clinical outcome in pancreatic cancer patients.
Author: Hasegawa, Shinichiro|Nagano, Hiroaki|Konno, Masamitsu|Eguchi, Hidetoshi|Tomokuni, Akira|Tomimaru, Yoshito|Asaoka, Tadafumi|Wada, Hiroshi|Hama, Naoki|Kawamoto, Koichi|Marubashi, Shigeru|Nishida, Naohiro|Koseki, Jun|Mori, Masaki|Doki, Yuichiro|Ishii, Hidesh
PMID: 26648239
Journal: Cancer Lett. 2016 May 1;374(2):261-71.
Title: LincRNA-ROR promotes invasion, metastasis and tumor growth in pancreatic cancer through activating ZEB1 pathway.
Author: Zhan, Han-Xiang|Wang, Yao|Li, Ce|Xu, Jian-Wei|Zhou, Bin|Zhu, Jian-Kang|Han, Hai-Feng|Wang, Lei|Wang, Yun-Shan|Hu, San-Yuan
PMID: 26898939
Journal: Biochem Biophys Res Commun. 2016 Apr 1;472(2):346-52.
Title: miR-1271 inhibits migration, invasion and epithelial-mesenchymal transition by targeting ZEB1 and TWIST1 in pancreatic cancer cells.
Author: Liu, Huaize|Wang, Han|Liu, Xiaoxiao|Yu, Tingting
PMID: 26940738
Journal: Mol Pharm. 2016 Jun 6;13(6):1822-32.
Title: Micelle Mixtures for Coadministration of Gemcitabine and GDC-0449 To Treat Pancreatic Cancer.
Author: Karaca, Melek|Dutta, Rinku|Ozsoy, Yildiz|Mahato, Ram I
PMID: 26981724
Journal: Onco Targets Ther. 2016 Jul 11;9:4225-37.
Title: Interleukin-32alpha inactivates JAK2/STAT3 signaling and reverses interleukin-6-induced epithelial-mesenchymal transition, invasion, and metastasis in pancreatic cancer cells.
Author: Chen, Jingfeng|Wang, Silu|Su, Jiadong|Chu, Guanyu|You, Heyi|Chen, Zongjing|Sun, Hongwei|Chen, Bicheng|Zhou, Mengtao
PMID: 27471397
Journal: Mol Cell Biol. 2016 Oct 13;36(21):2742-2754.
Title: Suppression of MicroRNA 200 Family Expression by Oncogenic KRAS Activation Promotes Cell Survival and Epithelial-Mesenchymal Transition in KRAS-Driven Cancer.
Author: Zhong, Xiaomin|Zheng, Lan|Shen, Jianfeng|Zhang, Dongmei|Xiong, Minmin|Zhang, Youyou|He, Xinhong|Tanyi, Janos L|Yang, Feng|Montone, Kathleen T|Chen, Xiaojun|Xu, Congjian|Xiang, Andy P|Huang, Qihong|Xu, Xiaowei|Zhang, Lin
PMID: 27550813
Journal: Sci Rep. 2016 Sep 14;6:32743.
Title: alpha-Mangostin-encapsulated PLGA nanoparticles inhibit pancreatic carcinogenesis by targeting cancer stem cells in human, and transgenic (Kras(G12D), and Kras(G12D)/tp53R270H) mice.
Author: Verma, Raj Kumar|Yu, Wei|Shrivastava, Anju|Shankar, Sharmila|Srivastava, Rakesh K
PMID: 27624879
Journal: Lab Invest. 2016 Dec;96(12):1268-1278.
Title: Inhibition of NF-kappa B pathway leads to deregulation of epithelial-mesenchymal transition and neural invasion in pancreatic cancer.
Author: Nomura, Alice|Majumder, Kaustav|Giri, Bhuwan|Dauer, Patricia|Dudeja, Vikas|Roy, Sabita|Banerjee, Sulagna|Saluja, Ashok K
PMID: 27775688
Journal: Int J Oncol. 2017 Jan;50(1):111-120.
Title: Oridonin inhibition and miR200b3p/ZEB1 axis in human pancreatic cancer.
Author: Gui, Zhifang|Luo, Feng|Yang, Yayang|Shen, Can|Li, Shuquan|Xu, Jian
PMID: 27878247
Journal: Mol Cancer Res. 2017 Apr;15(4):478-488.
Title: Potent EMT and CSC Phenotypes Are Induced By Oncostatin-M in Pancreatic Cancer.
Author: Smigiel, Jacob M|Parameswaran, Neetha|Jackson, Mark W
PMID: 28053127
Journal: J Hepatobiliary Pancreat Sci. 2017 Mar;24(3):176-184.
Title: Analysis of the origin of anaplastic pancreatic cancer and the mechanism of its dedifferentiation.
Author: Miura, Kotaro|Kimura, Kenjiro|Amano, Ryosuke|Yamazoe, Sadaaki|Ohira, Go|Nishio, Kohei|Kametani, Naoki|Hirakawa, Kosei|Ohira, Masaichi
PMID: 28064441
Journal: Oncotarget. 2017 Apr 11;8(15):24978-24987.
Title: The mir-675-5p regulates the progression and development of pancreatic cancer via the UBQLN1-ZEB1-mir200 axis.
Author: Wang, Jue|Zhang, Youli|Wei, Hong|Zhang, Xingxing|Wu, Yan|Gong, Aihua|Xia, Yu|Wang, Wenbing|Xu, Min
PMID: 28212565
Journal: J Pathol. 2017 Jun;242(2):221-233.
Title: Thymidylate synthase is functionally associated with ZEB1 and contributes to the epithelial-to-mesenchymal transition of cancer cells.
Author: Siddiqui, Aarif|Vazakidou, Maria Eleni|Schwab, Annemarie|Napoli, Francesca|Fernandez-Molina, Cristina|Rapa, Ida|Stemmler, Marc P|Volante, Marco|Brabletz, Thomas|Ceppi, Paolo
PMID: 28337746
Journal: Oncotarget. 2017 Jun 13;8(24):39048-39063.
Title: CBX7 negatively regulates migration and invasion in glioma via Wnt/beta-catenin pathway inactivation.
Author: Bao, Zhongyuan|Xu, Xiupeng|Liu, Yinlong|Chao, Honglu|Lin, Chao|Li, Zheng|You, Yongping|Liu, Ning|Ji, Jing
PMID: 28388562
Journal: Nat Cell Biol. 2017 May;19(5):518-529.
Title: The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer.
Author: Krebs, Angela M|Mitschke, Julia|Lasierra Losada, Maria|Schmalhofer, Otto|Boerries, Melanie|Busch, Hauke|Boettcher, Martin|Mougiakakos, Dimitrios|Reichardt, Wilfried|Bronsert, Peter|Brunton, Valerie G|Pilarsky, Christian|Winkler, Thomas H|Brabletz, Simone|
PMID: 28414315
Journal: Oncotarget. 2017 May 9;8(19):31435-31448.
Title: Prognostic significance of ZEB1 and ZEB2 in digestive cancers: a cohort-based analysis and secondary analysis.
Author: Chen, Huihui|Lu, Wei|Huang, Chongjie|Ding, Kefeng|Xia, Dajing|Wu, Yihua|Cai, Mao
PMID: 28416756
Journal: Nat Cell Biol. 2017 Apr 27;19(5):416-418.
Title: Context-specific roles of EMT programmes in cancer cell dissemination.
Author: Nieto, M Angela
PMID: 28446813
Journal: Mod Pathol. 2017 Aug;30(8):1116-1125.
Title: MicroRNA dysregulation in the tumor microenvironment influences the phenotype of pancreatic cancer.
Author: Karamitopoulou, Eva|Haemmig, Stefan|Baumgartner, Ulrich|Schlup, Cornelia|Wartenberg, Martin|Vassella, Erik
PMID: 28548126
Journal: Transl Oncol. 2017 Aug;10(4):578-588.
Title: The Role of Fibroblasts in Pancreatic Cancer: Extracellular Matrix Versus Paracrine Factors.
Author: Bolm, Louisa|Cigolla, Simon|Wittel, Uwe A|Hopt, Ulrich T|Keck, Tobias|Rades, Dirk|Bronsert, Peter|Wellner, Ulrich Friedrich
PMID: 28658650
Journal: Cell Death Dis. 2017 Jul 13;8(7):e2924.
Title: Linc-DYNC2H1-4 promotes EMT and CSC phenotypes by acting as a sponge of miR-145 in pancreatic cancer cells.
Author: Gao, Yuran|Zhang, Zhicheng|Li, Kai|Gong, Liying|Yang, Qingzhu|Huang, Xuemei|Hong, Chengcheng|Ding, Mingfeng|Yang, Huanjie
PMID: 28703793
Journal: Dokl Biochem Biophys. 2017 Jul;475(1):259-263.
Title: Dependence of expression of regulatory master genes of embryonic development in pancreatic cancer cells on the intracellular concentration of the master regulator PDX1.
Author: Kondratyeva, L G|Didych, D A|Chernov, I P|Kopantzev, E P|Stukacheva, E A|Vinogradova, T V|Sverdlov, E D
PMID: 28864896
Journal: Dokl Biochem Biophys. 2017 Jul;475(1):267-270.
Title: Expression of transcription factor genes in cell lines corresponding to different stages of pancreatic cancer progression.
Author: Abjalimov, I R|Zinovyeva, M V|Nikolaev, L G|Kopantzeva, M R|Kopantzev, E P|Sverdlov, E D
PMID: 28864901
Journal: Biochem Biophys Res Commun. 2017 Nov 4;493(1):455-460.
Title: A natural product toosendanin inhibits epithelial-mesenchymal transition and tumor growth in pancreatic cancer via deactivating Akt/mTOR signaling.
Author: Pei, Zhe|Fu, Wei|Wang, Gongping
PMID: 28870807
Journal: Carcinogenesis. 2017 Oct 1;38(10):1047-1056.
Title: Sanguinarine inhibits pancreatic cancer stem cell characteristics by inducing oxidative stress and suppressing sonic hedgehog-Gli-Nanog pathway.
Author: Ma, Yiming|Yu, Wei|Shrivastava, Anju|Alemi, Farzad|Lankachandra, Kamani|Srivastava, Rakesh K|Shankar, Sharmila
PMID: 28968696
Journal: Oncol Lett. 2017 Nov;14(5):5400-5408.
Title: Astaxanthin inhibits gemcitabine-resistant human pancreatic cancer progression through EMT inhibition and gemcitabine resensitization.
Author: Yan, Tao|Li, Hai-Ying|Wu, Jian-Song|Niu, Qiang|Duan, Wei-Hong|Han, Qing-Zeng|Ji, Wang-Ming|Zhang, Tao|Lv, Wei
PMID: 29098031
Journal: Cell Death Dis. 2017 Nov 9;8(11):e3168.
Title: Alternative polyadenylation of ZEB1 promotes its translation during genotoxic stress in pancreatic cancer cells.
Author: Passacantilli, Ilaria|Panzeri, Valentina|Bielli, Pamela|Farini, Donatella|Pilozzi, Emanuela|Fave, Gianfranco Delle|Capurso, Gabriele|Sette, Claudio
PMID: 29120411
Journal: Diagn Cytopathol. 2018 Feb;46(2):198-203.
Title: Cytopathological and immunocytochemical findings of pancreatic anaplastic carcinoma with ZEB1 expression by means of touch imprint cytology.
Author: Naito, Yoshiki|Kawahara, Akihiko|Taira, Tomoki|Takase, Yorihiko|Murata, Kazuya|Ishida, Yusuke|Okabe, Yoshinobu|Tanigawa, Masahiko|Mihara, Yutaro|Nakayama, Masamichi|Shimamatsu, Kazuhide|Yano, Hirohisa|Akiba, Jun
PMID: 28940869
Journal: J Cell Biochem. 2018 Jul;119(7):5308-5323.
Title: CUL4B promotes metastasis and proliferation in pancreatic cancer cells by inducing epithelial-mesenchymal transition via the Wnt/beta-catenin signaling pathway.
Author: He, Yue-Ming|Xiao, Yu-Sha|Wei, Lei|Zhang, Jia-Qiang|Peng, Cheng-Hong
PMID: 29274277
Journal: Mol Med Rep. 2018 Mar;17(3):3681-3689.
Title: Luteolin inhibits pancreatitisinduced acinarductal metaplasia, proliferation and epithelialmesenchymal transition of acinar cells.
Author: Huang, Xince|Bhugul, Pravin Avinash|Fan, Gang|Ye, Tingting|Huang, Shihao|Dai, Shengjie|Chen, Bicheng|Zhou, Mengtao
PMID: 29286098
Journal: Oncotarget. 2017 Dec 7;9(1):306-320.
Title: Prognostic significance of E-cadherin and ZEB1 expression in intraductal papillary mucinous neoplasm.
Author: Chang, Ye Rim|Park, Taesung|Park, Sung Hyo|Kim, Yong Kang|Lee, Kyoung Bun|Kim, Sun-Whe|Jang, Jin-Young
PMID: 29416615
Journal: Cancer Res. 2018 May 15;78(10):2624-2637.
Title: Zeb1 in Stromal Myofibroblasts Promotes Kras-Driven Development of Pancreatic Cancer.
Author: Sangrador, Irene|Molero, Xavier|Campbell, Fiona|Franch-Exposito, Sebastia|Rovira-Rigau, Maria|Samper, Esther|Dominguez-Fraile, Manuel|Fillat, Cristina|Castells, Antoni|Vaquero, Eva C
PMID: 29490942
Journal: Clin Cancer Res. 2018 Jul 1;24(13):3186-3196.
Title: ZIP4 Promotes Pancreatic Cancer Progression by Repressing ZO-1 and Claudin-1 through a ZEB1-Dependent Transcriptional Mechanism.
Author: Liu, Mingyang|Yang, Jingxuan|Zhang, Yuqing|Zhou, Zhijun|Cui, Xiaobo|Zhang, Liyang|Fung, Kar-Ming|Zheng, Wei|Allard, Felicia D|Yee, Eric U|Ding, Kai|Wu, Huanwen|Liang, Zhiyong|Zheng, Lei|Fernandez-Zapico, Martin E|Li, Yi-Ping|Bronze, Michael S|Morris, Kath
PMID: 29615456
Journal: Cancer Biol Ther. 2018 Jul 3;19(7):573-583.
Title: LncRNA ADPGK-AS1 promotes pancreatic cancer progression through activating ZEB1-mediated epithelial-mesenchymal transition.
Author: Song, Suzhen|Yu, Weihua|Lin, Sen|Zhang, Mingbao|Wang, Teng|Guo, Shuang|Wang, Hongbo
PMID: 29667486
Journal: Cell Physiol Biochem. 2018;46(5):1930-1938.
Title: PIK3R3 Promotes Metastasis of Pancreatic Cancer via ZEB1 Induced Epithelial-Mesenchymal Transition.
Author: Peng, Yun-Peng|Zhu, Yi|Yin, Ling-Di|Wei, Ji-Shu|Liu, Xin-Chun|Zhu, Xiao-Le|Miao, Yi
PMID: 29719293
Journal: Oncogene. 2018 Jul 3. pii: 10.1038/s41388-018-0382-1.
Title: Hypoxia-induced LncRNA-BX111 promotes metastasis and progression of pancreatic cancer through regulating ZEB1 transcription.
Author: Deng, Shi-Jiang|Chen, Heng-Yu|Ye, Zeng|Deng, Shi-Chang|Zhu, Shuai|Zeng, Zhu|He, Chi|Liu, Ming-Liang|Huang, Kang|Zhong, Jian-Xin|Xu, Feng-Yu|Li, Qiang|Liu, Yang|Wang, Chun-You|Zhao, Gang
PMID: 29970904
Journal: Mol Med Rep. 2018 Sep;18(3):3366-3374.
Title: Emodin inhibits pancreatic cancer EMT and invasion by upregulating microRNA1271.
Author: Li, Nan|Wang, Chunli|Zhang, Peng|You, Shengyi
PMID: 30066876
Journal: Front Immunol. 2018 Aug 15;9:1844.
Title: Human Surfactant Protein D Suppresses Epithelial-to-Mesenchymal Transition in Pancreatic Cancer Cells by Downregulating TGF-beta.
Author: Kaur, Anuvinder|Riaz, Muhammad Suleman|Singh, Shiv K|Kishore, Uday
PMID: 30158928
Journal: Dokl Biochem Biophys. 2018 Jul;481(1):219-221.
Title: Correlation between Expression of KLF5 and ZEB1 Transcription Factor Genes in Pancreatic Cancer.
Author: Zinovyeva, M V|Nikolaev, L G|Kondratyeva, L G|Vinogradova, T V|Sverdlov, E D
PMID: 30168064
Journal: IUBMB Life. 2018 Oct;70(10):1032-1039.
Title: Overexpressing PRMT1 Inhibits Proliferation and Invasion in Pancreatic Cancer by Inverse Correlation of ZEB1.
Author: Lin, Zhibin|Chen, Yao|Lin, Zhaoxian|Chen, Chunshan|Dong, Yangyang
PMID: 30194893
Journal: Mol Cells. 2018 Sep 30;41(9):868-880.
Title: EZH2-Mediated microRNA-139-5p Regulates Epithelial-Mesenchymal Transition and Lymph Node Metastasis of Pancreatic Cancer.
Author: Ma, Jin|Zhang, Jun|Weng, Yuan-Chi|Wang, Jian-Cheng
PMID: 30304920
Journal: Cancer Med. 2018 Oct 14.
Title: Vasohibin 2 promotes malignant behaviors of pancreatic cancer cells by inducing epithelial-mesenchymal transition via Hedgehog signaling pathway.
Author: Zhang, Ye|Xue, Xiaofeng|Zhao, Xiaoqian|Qin, Lei|Shen, Yu|Dou, Huiqiang|Sun, Jialin|Wang, Tong|Yang, Da-Qing
PMID: 30318866