Primary Site >> Pancreatic Cancer
Gene >> ZEB1
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Ref: Membrane-bound heparin-binding epidermal growth factor like growth factor regulates E-cadherin expression in pancreatic carcinoma cells. PMID: 17875687 |
Ref: Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway. PMID: 19276344 Ref: Troglitazone increases expression of E-cadherin and claudin 4 in human pancreatic cancer cells. PMID: 19285010 Ref: Integrative genomic analyses of ZEB2: Transcriptional regulation of ZEB2 based on SMADs, ETS1, HIF1alpha, POU/OCT, and NF-kappaB. PMID: 19424592 Ref: Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer. PMID: 19584296 Ref: Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells. PMID: 19654291 Ref: Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation. PMID: 19860666 Ref: The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs. PMID: 19935649 Ref: A resource for analysis of microRNA expression and function in pancreatic ductal adenocarcinoma cells. PMID: 20037478 |
Ref: NF-kappaB promotes epithelial-mesenchymal transition, migration and invasion of pancreatic carcinoma cells. PMID: 20350779 Ref: ZEB1 in Pancreatic Cancer. PMID: 24281177 |
Ref: Sulforaphane synergizes with quercetin to inhibit self-renewal capacity of pancreatic cancer stem cells. PMID: 21196331 Ref: DCAMKL-1 regulates epithelial-mesenchymal transition in human pancreatic cells through a miR-200a-dependent mechanism. PMID: 21285251 Ref: Resveratrol inhibits pancreatic cancer stem cell characteristics in human and KrasG12D transgenic mice by inhibiting pluripotency maintaining factors and epithelial-mesenchymal transition. PMID: 21304978 Ref: Notch-1 induces epithelial-mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells. PMID: 21463919 Ref: Over-expression of FoxM1 leads to epithelial-mesenchymal transition and cancer stem cell phenotype in pancreatic cancer cells. PMID: 21503965 Ref: Targeting epigenetic regulation of miR-34a for treatment of pancreatic cancer by inhibition of pancreatic cancer stem cells. PMID: 21909380 |
Ref: Inhibition of sonic hedgehog pathway and pluripotency maintaining factors regulate human pancreatic cancer stem cell characteristics. PMID: 21796625 Ref: A ZEB1-HDAC pathway enters the epithelial to mesenchymal transition world in pancreatic cancer. PMID: 22147511 Ref: Recruitment of histone deacetylases HDAC1 and HDAC2 by the transcriptional repressor ZEB1 downregulates E-cadherin expression in pancreatic cancer. PMID: 22147512 Ref: Epithelial-mesenchymal transition and mesenchymal-epithelial transition via regulation of ZEB-1 and ZEB-2 expression in pancreatic cancer. PMID: 22213144 Ref: MUC4 potentiates invasion and metastasis of pancreatic cancer cells through stabilization of fibroblast growth factor receptor 1. PMID: 22791819 Ref: Hypoxia induces EMT in low and highly aggressive pancreatic tumor cells but only cells with cancer stem cell characteristics acquire pronounced migratory potential. PMID: 23050024 Ref: Epithelial-to-mesenchymal transition in pancreatic ductal adenocarcinoma and pancreatic tumor cell lines: the role of neutrophils and neutrophil-derived elastase. PMID: 23227088 |
Ref: Macrophage migration inhibitory factor induces epithelial to mesenchymal transition, enhances tumor aggressiveness and predicts clinical outcome in resected pancreatic ductal adenocarcinoma. PMID: 22821831 Ref: EGCG inhibits growth of human pancreatic tumors orthotopically implanted in Balb C nude mice through modulation of FKHRL1/FOXO3a and neuropilin. PMID: 22971992 Ref: Sulforaphane regulates self-renewal of pancreatic cancer stem cells through the modulation of Sonic hedgehog-GLI pathway. PMID: 23129257 Ref: GANT-61 inhibits pancreatic cancer stem cell growth in vitro and in NOD/SCID/IL2R gamma null mice xenograft. PMID: 23200667 Ref: Caffeic Acid phenethyl ester inhibits epithelial-mesenchymal transition of human pancreatic cancer cells. PMID: 23662124 Ref: FOXL1, a novel candidate tumor suppressor, inhibits tumor aggressiveness and predicts outcome in human pancreatic cancer. PMID: 23801748 Ref: Subtype-specific MEK-PI3 kinase feedback as a therapeutic target in pancreatic adenocarcinoma. PMID: 23918833 Ref: DCLK1 regulates pluripotency and angiogenic factors via microRNA-dependent mechanisms in pancreatic cancer. PMID: 24040120 Ref: MUC1 regulates expression of multiple microRNAs involved in pancreatic tumor progression, including the miR-200c/141 cluster. PMID: 24143167 |
Ref: Embelin suppresses pancreatic cancer growth by modulating tumor immune microenvironment. PMID: 24389175 Ref: miR-203 inhibits tumor cell migration and invasion via caveolin-1 in pancreatic cancer cells. PMID: 24520289 Ref: MiR-200a inhibits epithelial-mesenchymal transition of pancreatic cancer stem cell. PMID: 24521357 Ref: Embelin suppresses growth of human pancreatic cancer xenografts, and pancreatic cancer cells isolated from KrasG12D mice by inhibiting Akt and Sonic hedgehog pathways. PMID: 24694877 Ref: XMD8-92 inhibits pancreatic tumor xenograft growth via a DCLK1-dependent mechanism. PMID: 24880079 Ref: Prognostic significance of Zinc finger E-box binding homeobox 1 (ZEB1) expression in cancer cells and cancer-associated fibroblasts in pancreatic head cancer. PMID: 24929761 Ref: Clobenpropit enhances anti-tumor effect of gemcitabine in pancreatic cancer. PMID: 25024609 Ref: USP22 promotes epithelial-mesenchymal transition via the FAK pathway in pancreatic cancer cells. PMID: 25070659 Ref: Cancer cell invasion and EMT marker expression: a three-dimensional study of the human cancer-host interface. PMID: 25081610 Ref: The inhibitory effect of heat treatment against epithelial-mesenchymal transition (EMT) in human pancreatic adenocarcinoma cell lines. PMID: 25120280 Ref: Down-regulation of 5-HT1B and 5-HT1D receptors inhibits proliferation, clonogenicity and invasion of human pancreatic cancer cells. PMID: 25170871 Ref: Elongation factor-2 kinase regulates TG2/beta1 integrin/Src/uPAR pathway and epithelial-mesenchymal transition mediating pancreatic cancer cells invasion. PMID: 25215932 Ref: CD166/ALCAM expression is characteristic of tumorigenicity and invasive and migratory activities of pancreatic cancer cells. PMID: 25221999 Ref: Down-regulation of 5-HT1B and 5-HT1D receptors inhibits proliferation, clonogenicity and invasion of human pancreatic cancer cells. PMID: 25268648 |
Ref: Mutated K-ras activates CDK8 to stimulate the epithelial-to-mesenchymal transition in pancreatic cancer in part via the Wnt/beta-catenin signaling pathway. PMID: 25305448 Ref: Lung metastasis of pancreatic carcinoma is regulated by TGFbeta signaling. PMID: 25409617 Ref: Pancreatic cancer cells express CD44 variant 9 and multidrug resistance protein 1 during mitosis. PMID: 25481101 Ref: [Effect of MSX2 interference on epithelial-mesenchymal transitions of pancreatic cancer cell line PANC-1]. PMID: 25736109 Ref: ZEB1-associated drug resistance in cancer cells is reversed by the class I HDAC inhibitor mocetinostat. PMID: 25872941 Ref: Expression of E-cadherin repressors SNAIL, ZEB1 and ZEB2 by tumour and stromal cells influences tumour-budding phenotype and suggests heterogeneity of stromal cells in pancreatic cancer. PMID: 25989272 Ref: A self-enforcing CD44s/ZEB1 feedback loop maintains EMT and stemness properties in cancer cells. PMID: 26077342 Ref: MicroRNA-200c overexpression plays an inhibitory role in human pancreatic cancer stem cells by regulating epithelial-mesenchymal transition. PMID: 26081037 Ref: Estrogen and tamoxifen up-regulate FXYD3 on breast cancer cells: assessing the differential roles of ER alpha and ZEB1. PMID: 26090296 Ref: CD4(+) T cells potently induce epithelial-mesenchymal-transition in premalignant and malignant pancreatic ductal epithelial cells-novel implications of CD4(+) T cells in pancreatic cancer development. PMID: 26137395 Ref: Anthothecol-encapsulated PLGA nanoparticles inhibit pancreatic cancer stem cell growth by modulating sonic hedgehog pathway. PMID: 26199979 Ref: PI3K/AKT/mTOR and sonic hedgehog pathways cooperate together to inhibit human pancreatic cancer stem cell characteristics and tumor growth. PMID: 26451606 Ref: MiR-652 inhibits acidic microenvironment-induced epithelial-mesenchymal transition of pancreatic cancer cells by targeting ZEB1. PMID: 26498682 Ref: KDM4B promotes epithelial-mesenchymal transition through up-regulation of ZEB1 in pancreatic cancer. PMID: 26511091 Ref: Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer. PMID: 26560028 |
Ref: Differential Regulation of ZEB1 and EMT by MAPK-Interacting Protein Kinases (MNK) and eIF4E in Pancreatic Cancer. PMID: 26609108 Ref: A crucial epithelial to mesenchymal transition regulator, Sox4/Ezh2 axis is closely related to the clinical outcome in pancreatic cancer patients. PMID: 26648239 Ref: LincRNA-ROR promotes invasion, metastasis and tumor growth in pancreatic cancer through activating ZEB1 pathway. PMID: 26898939 Ref: miR-1271 inhibits migration, invasion and epithelial-mesenchymal transition by targeting ZEB1 and TWIST1 in pancreatic cancer cells. PMID: 26940738 Ref: Micelle Mixtures for Coadministration of Gemcitabine and GDC-0449 To Treat Pancreatic Cancer. PMID: 26981724 Ref: Interleukin-32alpha inactivates JAK2/STAT3 signaling and reverses interleukin-6-induced epithelial-mesenchymal transition, invasion, and metastasis in pancreatic cancer cells. PMID: 27471397 Ref: Suppression of MicroRNA 200 Family Expression by Oncogenic KRAS Activation Promotes Cell Survival and Epithelial-Mesenchymal Transition in KRAS-Driven Cancer. PMID: 27550813 Ref: alpha-Mangostin-encapsulated PLGA nanoparticles inhibit pancreatic carcinogenesis by targeting cancer stem cells in human, and transgenic (Kras(G12D), and Kras(G12D)/tp53R270H) mice. PMID: 27624879 Ref: Inhibition of NF-kappa B pathway leads to deregulation of epithelial-mesenchymal transition and neural invasion in pancreatic cancer. PMID: 27775688 |
Ref: Oridonin inhibition and miR200b3p/ZEB1 axis in human pancreatic cancer. PMID: 27878247 Ref: Potent EMT and CSC Phenotypes Are Induced By Oncostatin-M in Pancreatic Cancer. PMID: 28053127 Ref: Analysis of the origin of anaplastic pancreatic cancer and the mechanism of its dedifferentiation. PMID: 28064441 Ref: The mir-675-5p regulates the progression and development of pancreatic cancer via the UBQLN1-ZEB1-mir200 axis. PMID: 28212565 Ref: Thymidylate synthase is functionally associated with ZEB1 and contributes to the epithelial-to-mesenchymal transition of cancer cells. PMID: 28337746 Ref: CBX7 negatively regulates migration and invasion in glioma via Wnt/beta-catenin pathway inactivation. PMID: 28388562 Ref: The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer. PMID: 28414315 Ref: Prognostic significance of ZEB1 and ZEB2 in digestive cancers: a cohort-based analysis and secondary analysis. PMID: 28416756 Ref: Context-specific roles of EMT programmes in cancer cell dissemination. PMID: 28446813 Ref: MicroRNA dysregulation in the tumor microenvironment influences the phenotype of pancreatic cancer. PMID: 28548126 Ref: The Role of Fibroblasts in Pancreatic Cancer: Extracellular Matrix Versus Paracrine Factors. PMID: 28658650 Ref: Linc-DYNC2H1-4 promotes EMT and CSC phenotypes by acting as a sponge of miR-145 in pancreatic cancer cells. PMID: 28703793 Ref: Dependence of expression of regulatory master genes of embryonic development in pancreatic cancer cells on the intracellular concentration of the master regulator PDX1. PMID: 28864896 Ref: Expression of transcription factor genes in cell lines corresponding to different stages of pancreatic cancer progression. PMID: 28864901 Ref: A natural product toosendanin inhibits epithelial-mesenchymal transition and tumor growth in pancreatic cancer via deactivating Akt/mTOR signaling. PMID: 28870807 Ref: Sanguinarine inhibits pancreatic cancer stem cell characteristics by inducing oxidative stress and suppressing sonic hedgehog-Gli-Nanog pathway. PMID: 28968696 Ref: Astaxanthin inhibits gemcitabine-resistant human pancreatic cancer progression through EMT inhibition and gemcitabine resensitization. PMID: 29098031 Ref: Alternative polyadenylation of ZEB1 promotes its translation during genotoxic stress in pancreatic cancer cells. PMID: 29120411 |
Ref: Cytopathological and immunocytochemical findings of pancreatic anaplastic carcinoma with ZEB1 expression by means of touch imprint cytology. PMID: 28940869 Ref: CUL4B promotes metastasis and proliferation in pancreatic cancer cells by inducing epithelial-mesenchymal transition via the Wnt/beta-catenin signaling pathway. PMID: 29274277 Ref: Luteolin inhibits pancreatitisinduced acinarductal metaplasia, proliferation and epithelialmesenchymal transition of acinar cells. PMID: 29286098 Ref: Prognostic significance of E-cadherin and ZEB1 expression in intraductal papillary mucinous neoplasm. PMID: 29416615 Ref: Zeb1 in Stromal Myofibroblasts Promotes Kras-Driven Development of Pancreatic Cancer. PMID: 29490942 Ref: ZIP4 Promotes Pancreatic Cancer Progression by Repressing ZO-1 and Claudin-1 through a ZEB1-Dependent Transcriptional Mechanism. PMID: 29615456 Ref: LncRNA ADPGK-AS1 promotes pancreatic cancer progression through activating ZEB1-mediated epithelial-mesenchymal transition. PMID: 29667486 Ref: PIK3R3 Promotes Metastasis of Pancreatic Cancer via ZEB1 Induced Epithelial-Mesenchymal Transition. PMID: 29719293 Ref: Hypoxia-induced LncRNA-BX111 promotes metastasis and progression of pancreatic cancer through regulating ZEB1 transcription. PMID: 29970904 Ref: Emodin inhibits pancreatic cancer EMT and invasion by upregulating microRNA1271. PMID: 30066876 Ref: Human Surfactant Protein D Suppresses Epithelial-to-Mesenchymal Transition in Pancreatic Cancer Cells by Downregulating TGF-beta. PMID: 30158928 Ref: Correlation between Expression of KLF5 and ZEB1 Transcription Factor Genes in Pancreatic Cancer. PMID: 30168064 Ref: Overexpressing PRMT1 Inhibits Proliferation and Invasion in Pancreatic Cancer by Inverse Correlation of ZEB1. PMID: 30194893 Ref: EZH2-Mediated microRNA-139-5p Regulates Epithelial-Mesenchymal Transition and Lymph Node Metastasis of Pancreatic Cancer. PMID: 30304920 Ref: Vasohibin 2 promotes malignant behaviors of pancreatic cancer cells by inducing epithelial-mesenchymal transition via Hedgehog signaling pathway. PMID: 30318866 |