Primary Site >> Colorectal Cancer

Gene >> YAP1

Journal: Curr Biol. 2007 Dec 4;17(23):2054-60. Epub 2007 Nov 1.
Title: YAP1 increases organ size and expands undifferentiated progenitor cells.
Author: Camargo, Fernando D|Gokhale, Sumita|Johnnidis, Jonathan B|Fu, Dongdong|Bell, George W|Jaenisch, Rudolf|Brummelkamp, Thijn R
PMID: 17980593
Journal: Cancer Res. 2008 Oct 15;68(20):8231-9.
Title: Netrin-1 induces apoptosis in human cervical tumor cells via the TAp73alpha tumor suppressor.
Author: Roperch, Jean-Pierre|El Ouadrani, Karima|Hendrix, Ann|Emami, Shahin|De Wever, Olivier|Melino, Gerry|Gespach, Christian
PMID: 18922894
Journal: Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):E1312-20.
Title: Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance.
Author: Zhou, Dawang|Zhang, Yongyou|Wu, Hongtan|Barry, Evan|Yin, Yi|Lawrence, Earl|Dawson, Dawn|Willis, Joseph E|Markowitz, Sanford D|Camargo, Fernando D|Avruch, Joseph
PMID: 22042863
Journal: J Biol Chem. 2012 Apr 6;287(15):11730-9.
Title: Wnt/beta-catenin signaling regulates Yes-associated protein (YAP) gene expression in colorectal carcinoma cells.
Author: Konsavage, Wesley M Jr|Kyler, Sydney L|Rennoll, Sherri A|Jin, Ge|Yochum, Gregory S
PMID: 22337891
Journal: Cell Cycle. 2012 Mar 15;11(6):1090-6.
Title: YAP oncogene overexpression supercharges colon cancer proliferation.
Author: Avruch, Joseph|Zhou, Dawang|Bardeesy, Nabeel
PMID: 22356765
Journal: Cancer Res. 2012 Aug 1;72(15):3817-27.
Title: Loss of RASSF1A synergizes with deregulated RUNX2 signaling in tumorigenesis.
Author: van der Weyden, Louise|Papaspyropoulos, Angelos|Poulogiannis, George|Rust, Alistair G|Rashid, Mamunur|Adams, David J|Arends, Mark J|O'Neill, Eric
PMID: 22710434
Journal: Mol Cell Biol. 2012 Sep;32(18):3648-62.
Title: A WNT/p21 circuit directed by the C-clamp, a sequence-specific DNA binding domain in TCFs.
Author: Hoverter, Nate P|Ting, Ju-Hui|Sundaresh, Suman|Baldi, Pierre|Waterman, Marian L
PMID: 22778133
Journal: Nature. 2013 Jan 3;493(7430):106-10.
Title: Restriction of intestinal stem cell expansion and the regenerative response by YAP.
Author: Barry, Evan R|Morikawa, Teppei|Butler, Brian L|Shrestha, Kriti|de la Rosa, Rosemarie|Yan, Kelley S|Fuchs, Charles S|Magness, Scott T|Smits, Ron|Ogino, Shuji|Kuo, Calvin J|Camargo, Fernando D
PMID: 23178811
Journal: PLoS One. 2013;8(1):e54211.
Title: TAZ expression as a prognostic indicator in colorectal cancer.
Author: Yuen, Hiu-Fung|McCrudden, Cian M|Huang, Yu-Han|Tham, Jill M|Zhang, Xiaoqian|Zeng, Qi|Zhang, Shu-Dong|Hong, WanJin
PMID: 23372686
Journal: Gastroenterology. 2013 Jun;144(7):1530-1542.e12.
Title: Yes-associated protein up-regulates Jagged-1 and activates the Notch pathway in human hepatocellular carcinoma.
Author: Tschaharganeh, Darjus Felix|Chen, Xin|Latzko, Philipp|Malz, Mona|Gaida, Matthias Martin|Felix, Klaus|Ladu, Sara|Singer, Stephan|Pinna, Federico|Gretz, Norbert|Sticht, Carsten|Tomasi, Maria Lauda|Delogu, Salvatore|Evert, Matthias|Fan, Biao|Ribback, Silvia|
PMID: 23419361
Journal: Tumour Biol. 2013 Aug;34(4):2169-74.
Title: Clinical and prognostic significance of Yes-associated protein in colorectal cancer.
Author: Wang, Yan|Xie, Chengyao|Li, Qingchang|Xu, Ke|Wang, Enhua
PMID: 23558963
Journal: PLoS One. 2013 Jun 10;8(6):e65539.
Title: Overexpression of YAP and TAZ is an independent predictor of prognosis in colorectal cancer and related to the proliferation and metastasis of colon cancer cells.
Author: Wang, Lijuan|Shi, Shengjia|Guo, Zhangyan|Zhang, Xiang|Han, Suxia|Yang, Angang|Wen, Weihong|Zhu, Qing
PMID: 23762387
Journal: Int J Oncol. 2013 Dec;43(6):1992-8.
Title: Regulation of YAP through an Akt-dependent process by 3, 3'-diindolylmethane in human colon cancer cells.
Author: Li, Xiu Juan|Leem, Sun-Hee|Park, Man Hee|Kim, Soo Mi
PMID: 24100865
Journal: Nat Commun. 2013;4:2976.
Title: Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase.
Author: Serrano, Isabel|McDonald, Paul C|Lock, Frances|Muller, William J|Dedhar, Shoukat
PMID: 24356468
Journal: J Transl Med. 2013 Dec 26;11:317.
Title: E2A suppresses invasion and migration by targeting YAP in colorectal cancer cells.
Author: Zhao, Hongchao|Huang, Ao|Li, Pu|Quan, Yingjun|Feng, Bo|Chen, Xuehua|Mao, Zhihai|Zhu, Zhenggang|Zheng, Minhua
PMID: 24369055
Journal: Clin Cancer Res. 2014 Feb 15;20(4):837-46.
Title: Colon cancer cells escape 5FU chemotherapy-induced cell death by entering stemness and quiescence associated with the c-Yes/YAP axis.
Author: Touil, Yasmine|Igoudjil, Wassila|Corvaisier, Matthieu|Dessein, Anne-Frederique|Vandomme, Jerome|Monte, Didier|Stechly, Laurence|Skrypek, Nicolas|Langlois, Carole|Grard, Georges|Millet, Guillaume|Leteurtre, Emmanuelle|Dumont, Patrick|Truant, Stephanie|Pruv
PMID: 24323901
Journal: Hepatology. 2014 Jun;59(6):2238-50.
Title: Functional genomics identified a novel protein tyrosine phosphatase receptor type F-mediated growth inhibition in hepatocarcinogenesis.
Author: Bera, Rabindranath|Chiou, Chih-Yung|Yu, Ming-Chin|Peng, Jei-Ming|He, Chung-Ru|Hsu, Chih-Yun|Huang, Hsiao-Ling|Ho, Uda Y|Lin, Shi-Ming|Lin, Yu-Jr|Hsieh, Sen-Yung
PMID: 24470239
Journal: PLoS One. 2014 Jun 3;9(6):e96767.
Title: Functional screening identifies miRNAs influencing apoptosis and proliferation in colorectal cancer.
Author: Christensen, Lise Lotte|Holm, Anja|Rantala, Juha|Kallioniemi, Olli|Rasmussen, Mads H|Ostenfeld, Marie S|Dagnaes-Hansen, Frederik|Oster, Bodil|Schepeler, Troels|Tobiasen, Heidi|Thorsen, Kasper|Sieber, Oliver M|Gibbs, Peter|Lamy, Philippe|Hansen, Torben F|J
PMID: 24892549
Journal: Cell. 2014 Jul 3;158(1):171-84.
Title: KRAS and YAP1 converge to regulate EMT and tumor survival.
Author: Shao, Diane D|Xue, Wen|Krall, Elsa B|Bhutkar, Arjun|Piccioni, Federica|Wang, Xiaoxing|Schinzel, Anna C|Sood, Sabina|Rosenbluh, Joseph|Kim, Jong W|Zwang, Yaara|Roberts, Thomas M|Root, David E|Jacks, Tyler|Hahn, William C
PMID: 24954536
Journal: Saudi J Gastroenterol. 2014 May-Jun;20(3):188-94.
Title: Expression of hippo pathway in colorectal cancer.
Author: Liang, Kun|Zhou, Guangxi|Zhang, Qi|Li, Jing|Zhang, Cuiping
PMID: 24976283
Journal: Int J Oncol. 2014 Dec;45(6):2511-21.
Title: Methylationassociated inactivation of LATS1 and its effect on demethylation or overexpression on YAP and cell biological function in human renal cell carcinoma.
Author: Chen, Ke-Hong|He, Jiang|Wang, De-Lin|Cao, Jian-Jia|Li, Mei-Cai|Zhao, Xiu-Min|Sheng, Xia|Li, Wen-Bin|Liu, Wu-Jiang
PMID: 25270913
Journal: Soft Matter. 2014 Nov 28;10(44):8829-37.
Title: Reprogramming cellular phenotype by soft collagen gels.
Author: Ali, M Yakut|Chuang, Chih-Yuan|Saif, M Taher A
PMID: 25284029
Journal: Clin Cancer Res. 2015 Jan 15;21(2):357-64.
Title: Significant association of oncogene YAP1 with poor prognosis and cetuximab resistance in colorectal cancer patients.
Author: Lee, Keun-Wook|Lee, Sung Sook|Kim, Sang-Bae|Sohn, Bo Hwa|Lee, Hyun-Sung|Jang, Hee-Jin|Park, Yun-Yong|Kopetz, Scott|Kim, Sung Soo|Oh, Sang Cheul|Lee, Ju-Seog
PMID: 25388162
Journal: Dev Biol. 2015 Jan 1;397(1):67-76.
Title: Drosophila C-terminal Src kinase regulates growth via the Hippo signaling pathway.
Author: Kwon, Hailey J|Waghmare, Indrayani|Verghese, Shilpi|Singh, Aditi|Singh, Amit|Kango-Singh, Madhuri
PMID: 25446534
Journal: Oncotarget. 2015 Jan 20;6(2):935-52.
Title: FGF8 promotes colorectal cancer growth and metastasis by activating YAP1.
Author: Liu, Rui|Huang, Shan|Lei, Yunlong|Zhang, Tao|Wang, Kui|Liu, Bo|Nice, Edouard C|Xiang, Rong|Xie, Ke|Li, Jingyi|Huang, Canhua
PMID: 25473897
Journal: Curr Biol. 2015 Feb 2;25(3):296-305.
Title: NDR functions as a physiological YAP1 kinase in the intestinal epithelium.
Author: Zhang, Lei|Tang, Fengyuan|Terracciano, Luigi|Hynx, Debby|Kohler, Reto|Bichet, Sandrine|Hess, Daniel|Cron, Peter|Hemmings, Brian A|Hergovich, Alexander|Schmitz-Rohmer, Debora
PMID: 25601544
Journal: Oncogene. 2015 Nov 19;34(47):5781-95.
Title: The membrane protein melanoma cell adhesion molecule (MCAM) is a novel tumor marker that stimulates tumorigenesis in hepatocellular carcinoma.
Author: Wang, J|Tang, X|Weng, W|Qiao, Y|Lin, J|Liu, W|Liu, R|Ma, L|Yu, W|Yu, Y|Pan, Q|Sun, F
PMID: 25728681
Journal: Nature. 2015 Mar 5;519(7541):57-62.
Title: A gp130-Src-YAP module links inflammation to epithelial regeneration.
Author: Taniguchi, Koji|Wu, Li-Wha|Grivennikov, Sergei I|de Jong, Petrus R|Lian, Ian|Yu, Fa-Xing|Wang, Kepeng|Ho, Samuel B|Boland, Brigid S|Chang, John T|Sandborn, William J|Hardiman, Gary|Raz, Eyal|Maehara, Yoshihiko|Yoshimura, Akihiko|Zucman-Rossi, Jessica|Guan
PMID: 25731159
Journal: J Mol Biol. 2015 Oct 23;427(21):3407-15.
Title: Crosstalk between Hippo and TGFbeta: Subcellular Localization of YAP/TAZ/Smad Complexes.
Author: Grannas, Karin|Arngarden, Linda|Lonn, Peter|Mazurkiewicz, Magdalena|Blokzijl, Andries|Zieba, Agata|Soderberg, Ola
PMID: 25937570
Journal: Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):7255-60.
Title: Netrin-1 exerts oncogenic activities through enhancing Yes-associated protein stability.
Author: Qi, Qi|Li, Dean Y|Luo, Hongbo R|Guan, Kun-Liang|Ye, Keqiang
PMID: 26039999
Journal: Folia Histochem Cytobiol. 2015;53(2):105-19.
Title: The Hippo pathway in colorectal cancer.
Author: Wierzbicki, Piotr M|Rybarczyk, Agnieszka
PMID: 26160682
Journal: Oncogenesis. 2015 Sep 7;4:e165.
Title: Stiff substrates increase YAP-signaling-mediated matrix metalloproteinase-7 expression.
Author: Nukuda, A|Sasaki, C|Ishihara, S|Mizutani, T|Nakamura, K|Ayabe, T|Kawabata, K|Haga, H
PMID: 26344692
Journal: Oncotarget. 2015 Oct 27;6(33):34658-68.
Title: Wnt activated beta-catenin and YAP proteins enhance the expression of non-coding RNA component of RNase MRP in colon cancer cells.
Author: Park, Jinjoo|Jeong, Sunjoo
PMID: 26415221
Journal: Sci Signal. 2015 Oct 6;8(397):fs18.
Title: Proteostasis trumps YAP in colon cancer.
Author: Avril, Tony|Chevet, Eric
PMID: 26443703
Journal: Sci Signal. 2015 Oct 6;8(397):ra98.
Title: Tumor-selective proteotoxicity of verteporfin inhibits colon cancer progression independently of YAP1.
Author: Zhang, Huabing|Ramakrishnan, Sadeesh K|Triner, Daniel|Centofanti, Brook|Maitra, Dhiman|Gyorffy, Balazs|Sebolt-Leopold, Judith S|Dame, Michael K|Varani, James|Brenner, Dean E|Fearon, Eric R|Omary, M Bishr|Shah, Yatrik M
PMID: 26443705
Journal: Nature. 2015 Oct 29;526(7575):715-8.
Title: Yap-dependent reprogramming of Lgr5(+) stem cells drives intestinal regeneration and cancer.
Author: Gregorieff, Alex|Liu, Yu|Inanlou, Mohammad R|Khomchuk, Yuliya|Wrana, Jeffrey L
PMID: 26503053
Journal: Pharmacogenomics J. 2016 Aug;16(4):312-9.
Title: Germline polymorphisms in genes involved in the Hippo pathway as recurrence biomarkers in stages II/III colon cancer.
Author: Sebio, A|Matsusaka, S|Zhang, W|Yang, D|Ning, Y|Stremitzer, S|Stintzing, S|Sunakawa, Y|Yamauchi, S|Fujimoto, Y|Ueno, M|Lenz, H-J
PMID: 26370619
Journal: Curr Med Chem. 2016;23(11):1171-84.
Title: Non-Photoinduced Biological Properties of Verteporfin.
Author: Gibault, Floriane|Corvaisier, Matthieu|Bailly, Fabrice|Huet, Guillemette|Melnyk, Patricia|Cotelle, Philippe
PMID: 26980565
Journal: J Neurosci. 2016 May 25;36(21):5833-49.
Title: Neogenin Promotes BMP2 Activation of YAP and Smad1 and Enhances Astrocytic Differentiation in Developing Mouse Neocortex.
Author: Huang, Zhihui|Sun, Dong|Hu, Jin-Xia|Tang, Fu-Lei|Lee, Dae-Hoon|Wang, Ying|Hu, Guoqing|Zhu, Xiao-Juan|Zhou, Jiliang|Mei, Lin|Xiong, Wen-Cheng
PMID: 27225772
Journal: Cell Stem Cell. 2016 Jul 7;19(1):38-51.
Title: Secreted Phospholipases A2 Are Intestinal Stem Cell Niche Factors with Distinct Roles in Homeostasis, Inflammation, and Cancer.
Author: Schewe, Matthias|Franken, Patrick F|Sacchetti, Andrea|Schmitt, Mark|Joosten, Rosalie|Bottcher, Rene|van Royen, Martin E|Jeammet, Louise|Payre, Christine|Scott, Patricia M|Webb, Nancy R|Gelb, Michael|Cormier, Robert T|Lambeau, Gerard|Fodde, Riccardo
PMID: 27292189
Journal: Cancer Res. 2016 Jul 1;76(13):3813-25.
Title: RARgamma Downregulation Contributes to Colorectal Tumorigenesis and Metastasis by Derepressing the Hippo-Yap Pathway.
Author: Guo, Peng-Da|Lu, Xing-Xing|Gan, Wen-Juan|Li, Xiu-Ming|He, Xiao-Shun|Zhang, Shen|Ji, Qing-Hua|Zhou, Feng|Cao, Yue|Wang, Jing-Ru|Li, Jian-Ming|Wu, Hua
PMID: 27325643
Journal: Tumour Biol. 2016 Sep;37(9):12485-12495.
Title: IGF2 knockdown in two colorectal cancer cell lines decreases survival, adhesion and modulates survival-associated genes.
Author: Rogers, Michael A|Kalter, Verena|Strowitzki, Moritz|Schneider, Martin|Lichter, Peter
PMID: 27337954
Journal: Cell Physiol Biochem. 2016;39(2):481-90.
Title: Verteporfin can Reverse the Paclitaxel Resistance Induced by YAP Over-Expression in HCT-8/T Cells without Photoactivation through Inhibiting YAP Expression.
Author: Pan, Wang|Wang, Qian|Zhang, Yi|Zhang, Naishu|Qin, Jiamin|Li, Wei|Wang, Jing|Wu, Fangfang|Cao, Lingsen|Xu, Guanglin
PMID: 27383277
Journal: Mol Med Rep. 2016 Sep;14(3):2625-31.
Title: The clinical significance of forkhead box protein A1 and its role in colorectal cancer.
Author: Ma, Wenqi|Jiang, Jue|Li, Miao|Wang, Hua|Zhang, Hongli|He, Xin|Huang, Lili|Zhou, Qi
PMID: 27484093
Journal: Oncotarget. 2016 Sep 6;7(36):58315-58330.
Title: G-protein-coupled receptors mediate omega-3 PUFAs-inhibited colorectal cancer by activating the Hippo pathway.
Author: Zhang, Kun|Hu, Zhimei|Qi, Haixia|Shi, Zhemin|Chang, Yanan|Yao, Qingbin|Cui, Hongmei|Zheng, Lina|Han, Yawei|Han, Xiaohui|Zhang, Zhen|Chen, Ting|Hong, Wei
PMID: 27506947
Journal: Cancer Res. 2016 Oct 1;76(19):5615-5627.
Title: RBM5-AS1 Is Critical for Self-Renewal of Colon Cancer Stem-like Cells.
Author: Di Cecilia, Serena|Zhang, Fan|Sancho, Ana|Li, SiDe|Aguilo, Francesca|Sun, Yifei|Rengasamy, Madhumitha|Zhang, Weijia|Del Vecchio, Luigi|Salvatore, Francesco|Walsh, Martin J
PMID: 27520449
Journal: Oncotarget. 2016 Aug 30;7(35):56699-56712.
Title: Regulation of cellular quiescence by YAP/TAZ and Cyclin E1 in colon cancer cells: Implication in chemoresistance and cancer relapse.
Author: Corvaisier, Matthieu|Bauzone, Marjolaine|Corfiotti, Francois|Renaud, Florence|El Amrani, Mehdi|Monte, Didier|Truant, Stephanie|Leteurtre, Emmanuelle|Formstecher, Pierre|Van Seuningen, Isabelle|Gespach, Christian|Huet, Guillemette
PMID: 27527859
Journal: Neoplasia. 2016 Aug;18(8):512-23.
Title: NHERF1/EBP50 Suppresses Wnt-beta-Catenin Pathway-Driven Intestinal Neoplasia.
Author: Georgescu, Maria-Magdalena|Gagea, Mihai|Cote, Gilbert
PMID: 27566107
Journal: Oncol Rep. 2016 Dec;36(6):3619-3626.
Title: Angiomotin promotes the malignant potential of colon cancer cells by activating the YAP-ERK/PI3K-AKT signaling pathway.
Author: Zhang, Yan|Yuan, Jun|Zhang, Xinli|Yan, Futang|Huang, Minggang|Wang, Tao|Zheng, Xiao|Zhang, Ming
PMID: 27779692
Journal: Gastroenterology. 2017 Feb;152(3):616-630.
Title: Prostaglandin E2 Activates YAP and a Positive-Signaling Loop to Promote Colon Regeneration After Colitis but Also Carcinogenesis in Mice.
Author: Kim, Han-Byul|Kim, Minchul|Park, Young-Soo|Park, Intae|Kim, Tackhoon|Yang, Sung-Yeun|Cho, Charles J|Hwang, DaeHee|Jung, Jin-Hak|Markowitz, Sanford D|Hwang, Sung Wook|Yang, Suk-Kyun|Lim, Dae-Sik|Myung, Seung-Jae
PMID: 27864128
Journal: Nat Commun. 2017 Jan 4;8:14058.
Title: VGLL4 targets a TCF4-TEAD4 complex to coregulate Wnt and Hippo signalling in colorectal cancer.
Author: Jiao, Shi|Li, Chuanchuan|Hao, Qian|Miao, Haofei|Zhang, Lei|Li, Lin|Zhou, Zhaocai
PMID: 28051067
Journal: Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):1643-1648.
Title: YAP-IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis.
Author: Taniguchi, Koji|Moroishi, Toshiro|de Jong, Petrus R|Krawczyk, Michal|Grebbin, Britta Moyo|Luo, Huiyan|Xu, Rui-Hua|Golob-Schwarzl, Nicole|Schweiger, Caroline|Wang, Kepeng|Di Caro, Giuseppe|Feng, Ying|Fearon, Eric R|Raz, Eyal|Kenner, Lukas|Farin, Henner F|G
PMID: 28130546
Journal: J Hematol Oncol. 2017 Feb 28;10(1):60.
Title: Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways.
Author: Huang, Yan-Jiun|Yang, Ching-Kuo|Wei, Po-Li|Huynh, Thanh-Tuan|Whang-Peng, Jacqueline|Meng, Tzu-Ching|Hsiao, Michael|Tzeng, Yew-Ming|Wu, Alexander Th|Yen, Yun
PMID: 28241877
Journal: Cancer Res. 2017 May 1;77(9):2413-2423.
Title: Endothelin Promotes Colorectal Tumorigenesis by Activating YAP/TAZ.
Author: Wang, Zhen|Liu, Peng|Zhou, Xin|Wang, Tianxiang|Feng, Xu|Sun, Yi-Ping|Xiong, Yue|Yuan, Hai-Xin|Guan, Kun-Liang
PMID: 28249901
Journal: J Hematol Oncol. 2017 Mar 29;10(1):79.
Title: Integrated analysis identifies microRNA-195 as a suppressor of Hippo-YAP pathway in colorectal cancer.
Author: Sun, Min|Song, Haibin|Wang, Shuyi|Zhang, Chunxiao|Zheng, Liang|Chen, Fangfang|Shi, Dongdong|Chen, Yuanyuan|Yang, Chaogang|Xiang, Zhenxian|Liu, Qing|Wei, Chen|Xiong, Bin
PMID: 28356122
Journal: Cancer Cell. 2017 May 8;31(5):621-634.e6.
Title: TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cells.
Author: Diamantopoulou, Zoi|White, Gavin|Fadlullah, Muhammad Z H|Dreger, Marcel|Pickering, Karen|Maltas, Joe|Ashton, Garry|MacLeod, Ruth|Baillie, George S|Kouskoff, Valerie|Lacaud, Georges|Murray, Graeme I|Sansom, Owen J|Hurlstone, Adam F L|Malliri, Angeliki
PMID: 28416184
Journal: Cancer Lett. 2017 Jul 28;399:53-63.
Title: MiR-590-5p, a density-sensitive microRNA, inhibits tumorigenesis by targeting YAP1 in colorectal cancer.
Author: Ou, Chunlin|Sun, Zhenqiang|Li, Xiayu|Li, Xiaoling|Ren, Weiguo|Qin, Zailong|Zhang, Xuemei|Yuan, Weitang|Wang, Jia|Yu, Wentao|Zhang, Shiwen|Peng, Qiu|Yan, Qun|Xiong, Wei|Li, Guiyuan|Ma, Jian
PMID: 28433598
Journal: Theranostics. 2017 Feb 27;7(5):1114-1132.
Title: The YAP1/SIX2 axis is required for DDX3-mediated tumor aggressiveness and cetuximab resistance in KRAS-wild-type colorectal cancer.
Author: Wu, De-Wei|Lin, Po-Lin|Wang, Lee|Huang, Chi-Chou|Lee, Huei
PMID: 28435452
Journal: Oncol Lett. 2017 Apr;13(4):2656-2664.
Title: Inhibitory effect and mechanism of exogenous mammalian sterile 20-like kinase 1 on the growth of human colorectal cancer.
Author: Wu, Jian|Yang, Xiaohong|Lu, Hongfei|Liu, Liqiao|Xu, Baohua|Zheng, Shuangyan|Yu, Bo|Jie, Kemin|Wan, Fusheng
PMID: 28454447
Journal: Cancer Cell. 2017 May 8;31(5):607-608.
Title: A TIAM Double Hit to Oppose YAP/TAZ.
Author: Azzolin, Luca|Piccolo, Stefano
PMID: 28486099
Journal: Cell Prolif. 2017 Aug;50(4).
Title: SAV1 represses the development of human colorectal cancer by regulating the Akt-mTOR pathway in a YAP-dependent manner.
Author: Jiang, Jianwu|Chang, Wei|Fu, Yang|Gao, Yongshun|Zhao, Chunlin|Zhang, Xiefu|Zhang, Shuijun
PMID: 28618450
Journal: Int J Biol Sci. 2017 Jun 1;13(6):772-781.
Title: Angiomotin Family Members: Oncogenes or Tumor Suppressors?
Author: Lv, Meng|Shen, Yanwei|Yang, Jiao|Li, Shuting|Wang, Biyuan|Chen, Zheling|Li, Pan|Liu, Peijun|Yang, Jin
PMID: 28656002
Journal: Int J Mol Med. 2017 Sep;40(3):587-606.
Title: Molecular genetics and targeted therapy of WNT-related human diseases (Review).
Author: Katoh, Masuko|Katoh, Masaru
PMID: 28731148
Journal: J Biol Chem. 2017 Oct 13;292(41):17046-17056.
Title: Hypoxia-inducible factor 2alpha (HIF-2alpha) promotes colon cancer growth by potentiating Yes-associated protein 1 (YAP1) activity.
Author: Ma, Xiaoya|Zhang, Huabing|Xue, Xiang|Shah, Yatrik M
PMID: 28848049
Journal: Oncotarget. 2017 Jul 22;8(35):58061-58071.
Title: MiR-590-3p promotes proliferation and metastasis of colorectal cancer via Hippo pathway.
Author: Sun, Zhen-Qiang|Shi, Ke|Zhou, Quan-Bo|Zeng, Xiang-Yue|Liu, Jinbo|Yang, Shuai-Xi|Wang, Qi-San|Li, Zhen|Wang, Gui-Xian|Song, Jun-Min|Yuan, Wei-Tang|Wang, Hai-Jiang
PMID: 28938537
Journal: J Exp Clin Cancer Res. 2017 Oct 16;36(1):144.
Title: YAP transcriptionally regulates COX-2 expression and GCCSysm-4 (G-4), a dual YAP/COX-2 inhibitor, overcomes drug resistance in colorectal cancer.
Author: Li, Wei|Cao, Yuanyuan|Xu, Jinling|Wang, Ying|Li, Weijie|Wang, Qian|Hu, Ziwei|Hao, Yaping|Hu, Li|Sun, Yawen|Xu, Guanglin|Ao, Guizhen
PMID: 29037225
Journal: Oncol Rep. 2017 Dec;38(6):3376-3386.
Title: Downregulation of miR-874-3p promotes chemotherapeutic resistance in colorectal cancer via inactivation of the Hippo signaling pathway.
Author: Que, Kaiqian|Tong, Yuanhe|Que, Ganbo|Li, Li|Lin, Hongcheng|Huang, Shuai|Wang, Ruoyu|Tang, Langlang
PMID: 29039607
Journal: Exp Ther Med. 2017 Oct;14(4):3831-3835.
Title: Upregulation of Yes-associated protein and transcriptional co-activator with PDZ-binding motif influences the behavior of LOVO human colon adenocarcinoma cells.
Author: Li, Yu|Li, Lan|Zhu, Min|Ye, Limin|Yang, Qian
PMID: 29042987
Journal: PLoS One. 2017 Oct 19;12(10):e0186334.
Title: Short-chain fatty acid receptors inhibit invasive phenotypes in breast cancer cells.
Author: Thirunavukkarasan, Madhumathi|Wang, Chao|Rao, Angad|Hind, Tatsuma|Teo, Yuan Ru|Siddiquee, Abrar Al-Mahmood|Goghari, Mohamed Ally Ibrahim|Kumar, Alan Prem|Herr, Deron R
PMID: 29049318
Journal: Oncotarget. 2017 Aug 11;8(43):75727-75741.
Title: Dual roles of yes-associated protein (YAP) in colorectal cancer.
Author: Ou, Chunlin|Sun, Zhenqiang|Li, Shen|Li, Guiyuan|Li, Xiayu|Ma, Jian
PMID: 29088905
Journal: Cell Physiol Biochem. 2017;44(5):2073-2089.
Title: YAP Inhibits the Apoptosis and Migration of Human Rectal Cancer Cells via Suppression of JNK-Drp1-Mitochondrial Fission-HtrA2/Omi Pathways.
Author: Li, Haijun|He, Fucheng|Zhao, Xin|Zhang, Yuan|Chu, Xi|Hua, Chunlan|Qu, Yunhui|Duan, Yu|Ming, Liang
PMID: 29241219
Journal: Oncotarget. 2017 Nov 11;8(64):107907-107919.
Title: Small-sized colorectal cancer cells harbor metastatic tumor-initiating cells.
Author: Mu, Lei|Huang, Kaiyu|Hu, Yibing|Yan, Chang|Li, Xiaolan|Tao, Deding|Gong, Jianping|Qin, Jichao
PMID: 29296212
Journal: Oncotarget. 2017 Nov 27;8(65):109301-109318.
Title: Ascl2 activation by YAP1/KLF5 ensures the self-renewability of colon cancer progenitor cells.
Author: Wei, Xiaolong|Ye, Jun|Shang, Yangyang|Chen, Haoyuan|Liu, Shanxi|Liu, Li|Wang, Rongquan
PMID: 29312609
Journal: Int J Radiat Biol. 2018 Jan;94(1):79-87.
Title: Significant expression of tafazzin (TAZ) protein in colon cancer cells and its downregulation by radiation.
Author: Pathak, Surajit|Banerjee, Antara|Meng, Wen-Jian|Kumar Nandy, Suman|Gopinath, Madhumala|Sun, Xiao-Feng
PMID: 29099643
Journal: Cell Cycle. 2018;17(1):102-109.
Title: TEAD4 promotes colorectal tumorigenesis via transcriptionally targeting YAP1.
Author: Tang, Jia-Yin|Yu, Chen-Yang|Bao, Yu-Jie|Chen, Lu|Chen, Jinxian|Yang, Sheng-Li|Chen, Hao-Yan|Hong, Jie|Fang, Jing-Yuan
PMID: 29157094
Journal: Genes (Basel). 2018 Jan 8;9(1). pii: genes9010020.
Title: Wnt, RSPO and Hippo Signalling in the Intestine and Intestinal Stem Cells.
Author: Kriz, Vitezslav|Korinek, Vladimir
PMID: 29316729
Journal: FEBS Lett. 2018 Feb;592(4):599-609.
Title: ARRDC3 suppresses colorectal cancer progression through destabilizing the oncoprotein YAP.
Author: Shen, Xu|Sun, Xiaohan|Sun, Bing|Li, Tao|Wu, Guoliang|Li, Yuantao|Chen, Lai|Liu, Qingxin|Cui, Meng|Zhou, Zizhang
PMID: 29364502
Journal: Oncotarget. 2017 Dec 19;9(2):2367-2383.
Title: Modified miR-15a has therapeutic potential for improving treatment of advanced stage colorectal cancer through inhibition of BCL2, BMI1, YAP1 and DCLK1.
Author: Fesler, Andrew|Liu, Hua|Ju, Jingfang
PMID: 29416778
Journal: Cancer Lett. 2018 Apr 28;420:260.
Title: Corrigendum to "MiR-590-5p, a density-sensitive microRNA, inhibits tumorigenesis by targeting YAP1 in colorectal cancer", [Canc. Lett. 399 (2017) 53-63].
Author: Ou, Chunlin|Sun, Zhenqiang|Li, Xiayu|Li, Xiaoling|Ren, Weiguo|Qin, Zailong|Zhang, Xuemei|Yuan, Weitang|Wang, Jia|Yu, Wentao|Zhang, Shiwen|Peng, Qiu|Yan, Qun|Xiong, Wei|Li, Guiyuan|Ma, Jian
PMID: 29429755
Journal: Clin Cancer Res. 2018 Apr 15;24(8):2015-2025.
Title: REGgamma Controls Hippo Signaling and Reciprocal NF-kappaB-YAP Regulation to Promote Colon Cancer.
Author: Wang, Qingwei|Gao, Xiao|Yu, Tong|Yuan, Lei|Dai, Jie|Wang, Weicang|Chen, Geng|Jiao, Chan|Zhou, Wang|Huang, Quan|Cui, Long|Zhang, Pei|Moses, Robb E|Yang, Jianhua|Chen, Fengyuan|Fu, Junjiang|Xiao, Jianru|Li, Lei|Dang, Yongyan|Li, Xiaotao
PMID: 29437787
Journal: Cancer Res. 2018 Jun 1;78(11):2925-2938.
Title: Tight Junction Protein Claudin-2 Promotes Self-Renewal of Human Colorectal Cancer Stem-like Cells.
Author: Paquet-Fifield, Sophie|Koh, Shir Lin|Cheng, Lesley|Beyit, Laura M|Shembrey, Carolyn|Molck, Christina|Behrenbruch, Corina|Papin, Marina|Gironella, Meritxell|Guelfi, Sophie|Nasr, Ramona|Grillet, Fanny|Prudhomme, Michel|Bourgaux, Jean-Francois|Castells, Anto
PMID: 29510994
Journal: Oncol Rep. 2018 May;39(5):2114-2126.
Title: Suppression of YAP by DDP disrupts colon tumor progression.
Author: Li, Kun|Guo, Jiwei|Wu, Yan|Jin, Dan|Jiang, Hong|Liu, Chengxia|Qin, Chengyong
PMID: 29512779
Journal: Thorac Cancer. 2018 Jul;9(7):785-793.
Title: Lysyl oxidase: A colorectal cancer biomarker of lung and hepatic metastasis.
Author: Liu, Yun|Wang, Guanghui|Liang, Zhonglin|Mei, Zubing|Wu, Tingyu|Cui, Ang|Liu, Chenying|Cui, Long
PMID: 29766649
Journal: Immunology. 2018 Oct;155(2):263-272.
Title: Tumour YAP1 and PTEN expression correlates with tumour-associated myeloid suppressor cell expansion and reduced survival in colorectal cancer.
Author: Yang, Rong|Cai, Ting-Ting|Wu, Xiao-Jun|Liu, Yi-Na|He, Jia|Zhang, Xiao-Shi|Ma, Gang|Li, Jiang
PMID: 29770434
Journal: Cell Death Dis. 2018 May 22;9(6):591.
Title: YAP-dependent ubiquitination and degradation of beta-catenin mediates inhibition of Wnt signalling induced by Physalin F in colorectal cancer.
Author: Chen, Chen|Zhu, Dongrong|Zhang, Hao|Han, Chao|Xue, Guimin|Zhu, Tianyu|Luo, Jianguang|Kong, Lingyi
PMID: 29789528
Journal: Cell Death Dis. 2018 May 29;9(6):640.
Title: miR-550a-3-5p acts as a tumor suppressor and reverses BRAF inhibitor resistance through the direct targeting of YAP.
Author: Choe, Min Ho|Yoon, Yina|Kim, Joon|Hwang, Sang-Gu|Han, Young-Hoon|Kim, Jae-Sung
PMID: 29844307
Journal: NPJ Precis Oncol. 2018 Jan 23;2(1):2.
Title: Vasodilator-stimulated phosphoprotein promotes liver metastasis of gastrointestinal cancer by activating a beta1-integrin-FAK-YAP1/TAZ signaling pathway.
Author: Xiang, Xiaoyu|Wang, Yuanguo|Zhang, Hongbin|Piao, Jinhua|Muthusamy, Selvaraj|Wang, Lei|Deng, Yibin|Zhang, Wei|Kuang, Rui|Billadeau, Daniel D|Huang, Shengbing|Lai, Jinping|Urrutia, Raul|Kang, Ningling
PMID: 29872721
Journal: J Crohns Colitis. 2018 Jul 30;12(8):993-1004.
Title: MicroRNA-590-5p Inhibits Intestinal Inflammation by Targeting YAP.
Author: Yu, Minhao|Luo, Yang|Cong, Zhijie|Mu, Yifei|Qiu, Yier|Zhong, Ming
PMID: 29912317
Journal: Proc Natl Acad Sci U S A. 2018 Jul 17;115(29):E6760-E6769.
Title: Zyxin promotes colon cancer tumorigenesis in a mitotic phosphorylation-dependent manner and through CDK8-mediated YAP activation.
Author: Zhou, Jiuli|Zeng, Yongji|Cui, Lian|Chen, Xingcheng|Stauffer, Seth|Wang, Zhan|Yu, Fang|Lele, Subodh M|Talmon, Geoffrey A|Black, Adrian R|Chen, Yuanhong|Dong, Jixin
PMID: 29967145
Journal: Am J Cancer Res. 2018 Jun 1;8(6):932-943. eCollection 2018.
Title: VGLL4 is a transcriptional cofactor acting as a novel tumor suppressor via interacting with TEADs.
Author: Deng, Xiaochong|Fang, Lin
PMID: 30034932
Journal: Mol Cancer. 2018 Jul 23;17(1):102.
Title: RASAL2 promotes tumor progression through LATS2/YAP1 axis of hippo signaling pathway in colorectal cancer.
Author: Pan, Yi|Tong, Joanna Hung Man|Lung, Raymond Wai Ming|Kang, Wei|Kwan, Johnny Sheung Him|Chak, Wing Po|Tin, Ka Yee|Chung, Lau Ying|Wu, Feng|Ng, Simon Siu Man|Mak, Tony Wing Chung|Yu, Jun|Lo, Kwok Wai|Chan, Anthony Wing Hung|To, Ka Fai
PMID: 30037330
Journal: J Pathol. 2018 Jul 26.
Title: Deletion of cadherin-17 enhances intestinal permeability and susceptibility to intestinal tumour formation.
Author: Chang, Ya-Yun|Yu, Linda Chia-Hui|Yu, I-Shing|Jhuang, Yu-Lin|Huang, Wei-Ju|Yang, Ching-Yao|Jeng, Yung-Ming
PMID: 30047135
Journal: Mol Carcinog. 2018 Aug 3.
Title: Functional significance of Hippo/YAP signaling for drug resistance in colorectal cancer.
Author: Song, Ruolan|Gu, Dongsheng|Zhang, Lining|Zhang, Xiaoli|Yu, Beiqin|Liu, Bingya|Xie, Jingwu
PMID: 30074279
Journal: Biomed Pharmacother. 2018 Nov;107:382-389.
Title: Long noncoding RNA kcna3 inhibits the progression of colorectal carcinoma through down-regulating YAP1 expression.
Author: Zhong, Xiaolin|Lu, Muhan|Wan, Juyi|Zhou, Tiejun|Qin, Bo
PMID: 30099342
Journal: Oncol Rep. 2018 Oct;40(4):2171-2182.
Title: Inhibition of YAP reverses primary resistance to EGFR inhibitors in colorectal cancer cells.
Author: Liu, Bi-Sheng|Xia, Hong-Wei|Zhou, Sheng|Liu, Qing|Tang, Qiu-Lin|Bi, Na-Xi|Zhou, Ji-Tao|Gong, Qi-Yong|Nie, Yong-Zhan|Bi, Feng
PMID: 30106444
Journal: EMBO Mol Med. 2018 Aug 24. pii: emmm.201708699.
Title: Cancer cell adaptation to hypoxia involves a HIF-GPRC5A-YAP axis.
Author: Greenhough, Alexander|Bagley, Clare|Heesom, Kate J|Gurevich, David B|Gay, David|Bond, Mark|Collard, Tracey J|Paraskeva, Chris|Martin, Paul|Sansom, Owen J|Malik, Karim|Williams, Ann C
PMID: 30143543
Journal: Exp Ther Med. 2018 Sep;16(3):2751-2755.
Title: Verteporfin enhances the sensitivity of LOVO/TAX cells to taxol via YAP inhibition.
Author: Shi, Ganggang|Wang, Hao|Han, Hongqiu|Gan, Jianchen|Wang, Hui
PMID: 30210616
Journal: J Histochem Cytochem. 2018 Sep 14:22155418799957.
Title: SCC-S2 Facilitates Tumor Proliferation and Invasion via Activating Wnt Signaling and Depressing Hippo Signaling in Colorectal Cancer Cells and Predicts Poor Prognosis of Patients.
Author: Yang, Chuanjia|Xu, Weixue|Meng, Xiangzhen|Zhou, Siqi|Zhang, Minglu|Cui, Dongxu
PMID: 30216108
Journal: J Cell Biochem. 2018 Sep 14.
Title: Matrix stiffness mediates stemness characteristics via activating the Yes-associated protein in colorectal cancer cells.
Author: Tan, Fengbo|Huang, Yan|Pei, Qian|Liu, Heli|Pei, Haiping|Zhu, Hong
PMID: 30218452
Journal: Med Sci Monit. 2018 Oct 3;24:7035-7042.
Title: Curcumin Induces Autophagy via Inhibition of Yes-Associated Protein (YAP) in Human Colon Cancer Cells.
Author: Zhu, Jing|Zhao, Bangxia|Xiong, Pingan|Wang, Chaoyun|Zhang, Juanjuan|Tian, Xiaohua|Huang, Yinghui
PMID: 30281585
Journal: Int J Surg. 2018 Oct 5;59:80-89.
Title: Association between PPP2CA expression and colorectal cancer prognosis tumor marker prognostic study.
Author: Yong, Lv|YuFeng, Zhu|Guang, Bai
PMID: 30296597
Journal: J Cell Physiol. 2018 Oct 26.
Title: Loss of HACE1 promotes colorectal cancer cell migration via upregulation of YAP1.
Author: Zhou, Zhen|Zhang, Hong-Sheng|Zhang, Zhong-Guo|Sun, Hong-Liang|Liu, Hui-Yun|Gou, Xiao-Meng|Yu, Xiao-Ying|Huang, Ying-Hui
PMID: 30362561