Primary Site >> Colorectal Cancer

Gene >> XRCC5

Journal: Cell Signal. 2000 Dec;12(11-12):745-50.
Title: Human colon carcinoma cell-line HCT116 transfected by antisense cDNA as a tool to study the Ku86 involvement in cell proliferation.
Author: Sadji, Z|Le Romancer, M|Lewin, M J|Reyl-Desmars, F
PMID: 11152960
Journal: Cancer Res. 2001 Dec 1;61(23):8381-4.
Title: Decreased expression of DNA-dependent protein kinase, a DNA repair protein, during human colon carcinogenesis.
Author: Rigas, B|Borgo, S|Elhosseiny, A|Balatsos, V|Manika, Z|Shinya, H|Kurihara, N|Go, M|Lipkin, M
PMID: 11731412
Journal: Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):832-7.
Title: Ku86 is essential in human somatic cells.
Author: Li, Gang|Nelsen, Caron|Hendrickson, Eric A
PMID: 11792868
Journal: Cancer. 2002 Sep 15;95(6):1199-205.
Title: The expression pattern of Ku correlates with tumor radiosensitivity and disease free survival in patients with rectal carcinoma.
Author: Komuro, Yasuhiro|Watanabe, Toshiaki|Hosoi, Yoshio|Matsumoto, Yoshihisa|Nakagawa, Keiichi|Tsuno, Nelson|Kazama, Shinsuke|Kitayama, Joji|Suzuki, Norio|Nagawa, Hirokazu
PMID: 12216085
Journal: Br J Cancer. 2003 Jan 27;88(2):202-5.
Title: Interaction between Ku80 protein and a widely used antibody to adenomatous polyposis coli.
Author: Roberts, G T|Davies, M L|Wakeman, J A
PMID: 12610503
Journal: BMC Genomics. 2003 Aug 9;4(1):32.
Title: Molecular cloning, genomic characterization and over-expression of a novel gene, XRRA1, identified from human colorectal cancer cell HCT116Clone2_XRR and macaque testis.
Author: Mesak, Felix M|Osada, Naoki|Hashimoto, Katsuyuki|Liu, Qing Y|Ng, Cheng E
PMID: 12908878
Journal: Eur J Histochem. 2004 Apr-Jun;48(2):103-10.
Title: The expression and the nuclear activity of the caretaker gene ku86 are modulated by somatostatin.
Author: Pucci, S|Bonanno, E|Pichiorri, F|Mazzarelli, P|Spagnoli, L G
PMID: 15208076
Journal: Int J Oncol. 2004 Aug;25(2):461-8.
Title: Up-regulation of DNA-dependent protein kinase activity and Sp1 in colorectal cancer.
Author: Hosoi, Yoshio|Watanabe, Toshiaki|Nakagawa, Keiichi|Matsumoto, Yoshihisa|Enomoto, Atsushi|Morita, Akinori|Nagawa, Hirokazu|Suzuki, Norio
PMID: 15254745
Journal: Mol Cancer Ther. 2005 Apr;4(4):529-36.
Title: Ku protein targeting by Ku70 small interfering RNA enhances human cancer cell response to topoisomerase II inhibitor and gamma radiation.
Author: Ayene, Iraimoudi S|Ford, Lance P|Koch, Cameron J
PMID: 15827325
Journal: Hepatogastroenterology. 2005 May-Jun;52(63):666-71.
Title: Evaluating the combination of molecular prognostic factors in tumor radiosensitivity in rectal cancer.
Author: Komuro, Yasuhiro|Watanabe, Toshiaki|Tsurita, Giichiro|Muto, Tetsuichiro|Nagawa, Hirokazu
PMID: 15966178
Journal: World J Gastroenterol. 2005 Nov 14;11(42):6694-700.
Title: DNA end binding activity and Ku70/80 heterodimer expression in human colorectal tumor.
Author: Mazzarelli, Paola|Parrella, Paola|Seripa, Davide|Signori, Emanuela|Perrone, Giuseppe|Rabitti, Carla|Borzomati, Domenico|Gabbrielli, Armando|Matera, Maria Giovanna|Gravina, Carolina|Caricato, Marco|Poeta, Maria Luana|Rinaldi, Monica|Valeri, Sergio|Coppola,
PMID: 16425368
Journal: Clin Cancer Res. 2006 Mar 1;12(5):1494-500.
Title: Expression of DNA double-strand break repair proteins ATM and BRCA1 predicts survival in colorectal cancer.
Author: Grabsch, Heike|Dattani, Mit|Barker, Lisa|Maughan, Nicola|Maude, Karen|Hansen, Olaf|Gabbert, Helmut E|Quirke, Phil|Mueller, Wolfram
PMID: 16533773
Journal: Hum Pathol. 2006 Apr;37(4):448-52.
Title: Loss of Ku70/Ku80 expression occurs more frequently in hereditary than in sporadic colorectal tumors. Tissue microarray study.
Author: Korabiowska, Monika|Cordon-Cardo, Carlos|Schinagl, Michael|Karaus, Michael|Stachura, Jerzy|Schulz, Harald|Fischer, Gosta
PMID: 16564919
Journal: Cancer Res. 2007 Jan 15;67(2):634-42.
Title: Adenovirus-mediated expression of a dominant negative Ku70 fragment radiosensitizes human tumor cells under aerobic and hypoxic conditions.
Author: He, Fuqiu|Li, Ligeng|Kim, Dooha|Wen, Bixiu|Deng, Xuelong|Gutin, Philip H|Ling, Clifton C|Li, Gloria C
PMID: 17234773
Journal: J Proteome Res. 2008 Aug;7(8):3254-66.
Title: The response of human colonocytes to folate deficiency in vitro: functional and proteomic analyses.
Author: Duthie, Susan J|Mavrommatis, Yiannis|Rucklidge, Gary|Reid, Martin|Duncan, Gary|Moyer, Mary P|Pirie, Lynn P|Bestwick, Charles S
PMID: 18597513
Journal: Cell Cycle. 2009 Feb 1;8(3):473-81. Epub 2009 Feb 18.
Title: Interleukin-6 affects cell death escaping mechanisms acting on Bax-Ku70-Clusterin interactions in human colon cancer progression.
Author: Pucci, Sabina|Mazzarelli, Paola|Sesti, Fabiola|Boothman, David A|Spagnoli, Luigi G
PMID: 19177010
Journal: Anticancer Res. 2009 Jun;29(6):2239-42.
Title: Significant association of Ku80 single nucleotide polymorphisms with colorectal cancer susceptibility in Central Taiwan.
Author: Yang, Mei-Due|Hsu, Yuan-Man|Kuo, Yung-Shun|Chen, Hua-Shiang|Chang, Chia-Ling|Wu, Cheng-Nan|Chang, Chao-Hsiang|Liao, Yu-Min|Wang, Hwei-Chung|Wang, Ming-Fu|Bau, Da-Tian
PMID: 19528488
Journal: Apoptosis. 2010 Feb;15(2):162-72.
Title: Cellular responses to etoposide: cell death despite cell cycle arrest and repair of DNA damage.
Author: Schonn, Ilona|Hennesen, Jana|Dartsch, Dorothee C
PMID: 20041303
Journal: Ann N Y Acad Sci. 2010 Apr;1194:60-71.
Title: Thymosin beta4 regulates migration of colon cancer cells by a pathway involving interaction with Ku80.
Author: Cierniewski, Czeslaw S|Papiewska-Pajak, Izabela|Malinowski, Mariusz|Sacewicz-Hofman, Izabela|Wiktorska, Magdalena|Kryczka, Jakub|Wysocki, Tomasz|Niewiarowska, Jolanta|Bednarek, Radoslaw
PMID: 20536451
Journal: J Vis Exp. 2010 Jul 28;(41). pii: 1931.
Title: Deficient Pms2, ERCC1, Ku86, CcOI in field defects during progression to colon cancer.
Author: Nguyen, Huy|Loustaunau, Cristy|Facista, Alexander|Ramsey, Lois|Hassounah, Nadia|Taylor, Hilary|Krouse, Robert|Payne, Claire M|Tsikitis, V Liana|Goldschmid, Steve|Banerjee, Bhaskar|Perini, Rafael F|Bernstein, Carol
PMID: 20689513
Journal: BMC Cancer. 2011 Aug 3;11:333.
Title: Targeting surface nucleolin with multivalent HB-19 and related Nucant pseudopeptides results in distinct inhibitory mechanisms depending on the malignant tumor cell type.
Author: Krust, Bernard|El Khoury, Diala|Nondier, Isabelle|Soundaramourty, Calaiselvy|Hovanessian, Ara G
PMID: 21812966
Journal: Genome Integr. 2012 Apr 11;3(1):3.
Title: Deficient expression of DNA repair enzymes in early progression to sporadic colon cancer.
Author: Facista, Alexander|Nguyen, Huy|Lewis, Cristy|Prasad, Anil R|Ramsey, Lois|Zaitlin, Beryl|Nfonsam, Valentine|Krouse, Robert S|Bernstein, Harris|Payne, Claire M|Stern, Stephen|Oatman, Nicole|Banerjee, Bhaskar|Bernstein, Carol
PMID: 22494821
Journal: Radiat Oncol. 2013 Aug 9;8:196.
Title: The different biological effects of single, fractionated and continuous low dose rate irradiation on CL187 colorectal cancer cells.
Author: Wang, Hao|Li, Jinna|Qu, Ang|Liu, Jingjia|Zhao, Yong|Wang, Junjie
PMID: 23937791
Journal: Oncotarget. 2014 May 15;5(9):2404-17.
Title: Alternative splicing of FBP-interacting repressor coordinates c-Myc, P27Kip1/cyclinE and Ku86/XRCC5 expression as a molecular sensor for bleomycin-induced DNA damage pathway.
Author: Rahmutulla, Bahityar|Matsushita, Kazuyuki|Satoh, Mamoru|Seimiya, Masanori|Tsuchida, Sachio|Kubo, Shuji|Shimada, Hideaki|Ohtsuka, Masayuki|Miyazaki, Masaru|Nomura, Fumio
PMID: 24811221
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2015 Jun;18(6):602-5.
Title: [Mechanism of radiotherapy sensitization of curcumin on rectal cancer cells].
Author: Wang, Dong|Qiu, Jianming|Yang, Guangen|Song, Yihuan|Deng, Qun|Zhang, Xiufeng
PMID: 26108778
Journal: Mol Biol Cell. 2017 Jan 1;28(1):192-200.
Title: Chromatin association of XRCC5/6 in the absence of DNA damage depends on the XPE gene product DDB2.
Author: Fantini, Damiano|Huang, Shuo|Asara, John M|Bagchi, Srilata|Raychaudhuri, Pradip
PMID: 28035050
Journal: PLoS One. 2017 Oct 19;12(10):e0186900.
Title: XRCC5 cooperates with p300 to promote cyclooxygenase-2 expression and tumor growth in colon cancers.
Author: Zhang, Zhifeng|Zheng, Fufu|Yu, Zhenlong|Hao, Jiajiao|Chen, Miao|Yu, Wendan|Guo, Wei|Chen, Yiming|Huang, Wenlin|Duan, Zhijun|Deng, Wuguo
PMID: 29049411
Journal: Anticancer Res. 2018 Jan;38(1):131-136.
Title: Traditional Chinese Medicine Curcumin Sensitizes Human Colon Cancer to Radiation by Altering the Expression of DNA Repair-related Genes.
Author: Yang, Guangen|Qiu, Jianming|Wang, Dong|Tao, Yong|Song, Yihuan|Wang, Hongtao|Tang, Juping|Wang, Xing|Sun, Y U|Yang, Zhijian|Hoffman, Robert M
PMID: 29277765
Journal: Mol Genet Genomic Med. 2018 Apr 17.
Title: Polymorphisms of DNA repair genes are associated with colorectal cancer in patients with Lynch syndrome.
Author: Kamiza, Abram B|Hsieh, Ling-Ling|Tang, Reiping|Chien, Huei-Tzu|Lai, Chih-Hsiung|Chiu, Li-Ling|Lo, Tsai-Ping|Hung, Kuan-Yi|You, Jeng-Fu|Wang, Wen-Chang|Hsiung, Chao A|Yeh, Chih-Ching
PMID: 29664240