Primary Site >> Colorectal Cancer
Gene >> XRCC5
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Ref: Human colon carcinoma cell-line HCT116 transfected by antisense cDNA as a tool to study the Ku86 involvement in cell proliferation. PMID: 11152960 |
Ref: Decreased expression of DNA-dependent protein kinase, a DNA repair protein, during human colon carcinogenesis. PMID: 11731412 |
Ref: Ku86 is essential in human somatic cells. PMID: 11792868 Ref: The expression pattern of Ku correlates with tumor radiosensitivity and disease free survival in patients with rectal carcinoma. PMID: 12216085 |
Ref: Interaction between Ku80 protein and a widely used antibody to adenomatous polyposis coli. PMID: 12610503 Ref: Molecular cloning, genomic characterization and over-expression of a novel gene, XRRA1, identified from human colorectal cancer cell HCT116Clone2_XRR and macaque testis. PMID: 12908878 |
Ref: The expression and the nuclear activity of the caretaker gene ku86 are modulated by somatostatin. PMID: 15208076 Ref: Up-regulation of DNA-dependent protein kinase activity and Sp1 in colorectal cancer. PMID: 15254745 |
Ref: Ku protein targeting by Ku70 small interfering RNA enhances human cancer cell response to topoisomerase II inhibitor and gamma radiation. PMID: 15827325 Ref: Evaluating the combination of molecular prognostic factors in tumor radiosensitivity in rectal cancer. PMID: 15966178 Ref: DNA end binding activity and Ku70/80 heterodimer expression in human colorectal tumor. PMID: 16425368 |
Ref: Expression of DNA double-strand break repair proteins ATM and BRCA1 predicts survival in colorectal cancer. PMID: 16533773 Ref: Loss of Ku70/Ku80 expression occurs more frequently in hereditary than in sporadic colorectal tumors. Tissue microarray study. PMID: 16564919 |
Ref: Adenovirus-mediated expression of a dominant negative Ku70 fragment radiosensitizes human tumor cells under aerobic and hypoxic conditions. PMID: 17234773 |
Ref: The response of human colonocytes to folate deficiency in vitro: functional and proteomic analyses. PMID: 18597513 |
Ref: Interleukin-6 affects cell death escaping mechanisms acting on Bax-Ku70-Clusterin interactions in human colon cancer progression. PMID: 19177010 Ref: Significant association of Ku80 single nucleotide polymorphisms with colorectal cancer susceptibility in Central Taiwan. PMID: 19528488 |
Ref: Cellular responses to etoposide: cell death despite cell cycle arrest and repair of DNA damage. PMID: 20041303 Ref: Thymosin beta4 regulates migration of colon cancer cells by a pathway involving interaction with Ku80. PMID: 20536451 Ref: Deficient Pms2, ERCC1, Ku86, CcOI in field defects during progression to colon cancer. PMID: 20689513 |
Ref: Targeting surface nucleolin with multivalent HB-19 and related Nucant pseudopeptides results in distinct inhibitory mechanisms depending on the malignant tumor cell type. PMID: 21812966 |
Ref: Deficient expression of DNA repair enzymes in early progression to sporadic colon cancer. PMID: 22494821 |
Ref: The different biological effects of single, fractionated and continuous low dose rate irradiation on CL187 colorectal cancer cells. PMID: 23937791 |
Ref: Alternative splicing of FBP-interacting repressor coordinates c-Myc, P27Kip1/cyclinE and Ku86/XRCC5 expression as a molecular sensor for bleomycin-induced DNA damage pathway. PMID: 24811221 |
Ref: [Mechanism of radiotherapy sensitization of curcumin on rectal cancer cells]. PMID: 26108778 |
Ref: Chromatin association of XRCC5/6 in the absence of DNA damage depends on the XPE gene product DDB2. PMID: 28035050 Ref: XRCC5 cooperates with p300 to promote cyclooxygenase-2 expression and tumor growth in colon cancers. PMID: 29049411 |
Ref: Traditional Chinese Medicine Curcumin Sensitizes Human Colon Cancer to Radiation by Altering the Expression of DNA Repair-related Genes. PMID: 29277765 Ref: Polymorphisms of DNA repair genes are associated with colorectal cancer in patients with Lynch syndrome. PMID: 29664240 |