Primary Site >> Colorectal Cancer

Gene >> XRCC3

Journal: Cancer Res. 1998 Feb 15;58(4):604-8.
Title: Nonconservative amino acid substitution variants exist at polymorphic frequency in DNA repair genes in healthy humans.
Author: Shen, M R|Jones, I M|Mohrenweiser, H
PMID: 9485007
Journal: Br J Cancer. 2003 Jul 21;89(2):333-7.
Title: Lack of involvement of nucleotide excision repair gene polymorphisms in colorectal cancer.
Author: Mort, R|Mo, L|McEwan, C|Melton, D W
PMID: 12865926
Journal: J Exp Clin Cancer Res. 2004 Jun;23(2):285-94.
Title: An association of polymorphism of DNA repair genes XRCC1 and XRCC3 with colorectal cancer.
Author: Krupa, R|Blasiak, J
PMID: 15354414
Journal: BMC Cancer. 2005 Jan 28;5:12.
Title: Polymorphisms of the XRCC1, XRCC3, & XPD genes, and colorectal cancer risk: a case-control study in Taiwan.
Author: Yeh, Chih-Ching|Sung, Fung-Chang|Tang, Reiping|Chang-Chieh, Chung Rong|Hsieh, Ling-Ling
PMID: 15679883
Journal: Cancer Lett. 2005 Jun 28;224(2):279-88.
Title: MS-920: DNA repair gene polymorphisms, diet and colorectal cancer risk in Taiwan.
Author: Yeh, Chih-Ching|Hsieh, Ling-Ling|Tang, Reiping|Chang-Chieh, Chung Rong|Sung, Fung-Chang
PMID: 15914278
Journal: Cancer Genet Cytogenet. 2005 Nov;163(1):38-43.
Title: The association of the DNA repair gene XRCC3 Thr241Met polymorphism with susceptibility to colorectal cancer in a Chinese population.
Author: Jin, Ming-Juan|Chen, Kun|Song, Liang|Fan, Chun-Hong|Chen, Qing|Zhu, Yi-Min|Ma, Xin-Yuan|Yao, Kai-Yan
PMID: 16271954
Journal: BMC Cancer. 2006 Mar 16;6:67.
Title: Polymorphisms of the XRCC1, XRCC3 and XPD genes and risk of colorectal adenoma and carcinoma, in a Norwegian cohort: a case control study.
Author: Skjelbred, Camilla Furu|Saebo, Mona|Wallin, Hakan|Nexo, Bjorn Andersen|Hagen, Per Christian|Lothe, Inger Marie Bowitz|Aase, Steinar|Johnson, Egil|Hansteen, Inger-Lise|Vogel, Ulla|Kure, Elin H
PMID: 16542436
Journal: Clin Cancer Res. 2006 Apr 1;12(7 Pt 1):2101-8.
Title: Polymorphisms in genes of nucleotide and base excision repair: risk and prognosis of colorectal cancer.
Author: Moreno, Victor|Gemignani, Federica|Landi, Stefano|Gioia-Patricola, Lydie|Chabrier, Amelie|Blanco, Ignacio|Gonzalez, Sara|Guino, Elisabet|Capella, Gabriel|Canzian, Federico
PMID: 16609022
Journal: Cancer Res. 2006 Jun 15;66(12):6018-24.
Title: Haploinsufficiency of RAD51B causes centrosome fragmentation and aneuploidy in human cells.
Author: Date, Osamu|Katsura, Mari|Ishida, Mari|Yoshihara, Takashi|Kinomura, Aiko|Sueda, Taijiro|Miyagawa, Kiyoshi
PMID: 16778173
Journal: J Biomed Sci. 2007 Mar;14(2):183-93. Epub 2006 Dec 27.
Title: Association between polymorphisms of biotransformation and DNA-repair genes and risk of colorectal cancer in Taiwan.
Author: Yeh, Chih-Ching|Sung, Fung-Chang|Tang, Reiping|Chang-Chieh, Chung Rong|Hsieh, Ling-Ling
PMID: 17191090
Journal: Eur J Cancer. 2008 Jun;44(9):1229-37.
Title: Pharmacogenetic approach for capecitabine or 5-fluorouracil selection to be combined with oxaliplatin as first-line chemotherapy in advanced colorectal cancer.
Author: Martinez-Balibrea, Eva|Abad, Albert|Aranda, Enrique|Sastre, Javier|Manzano, Jose Luis|Diaz-Rubio, Eduardo|Gomez-Espana, Auxiliadora|Aparicio, Jorge|Garcia, Teresa|Maestu, Inmaculada|Martinez-Cardus, Anna|Gines, Alba|Guino, Elisabet
PMID: 18448328
Journal: Anticancer Res. 2008 Sep-Oct;28(5B):2941-6.
Title: Polymorphisms of the DNA repair genes XRCC1 and XRCC3 and risk of lung and colorectal cancer: a case-control study in a Southern Italian population.
Author: Improta, Giuseppina|Sgambato, Alessandro|Bianchino, Gabriella|Zupa, Angela|Grieco, Vitina|La Torre, Giuseppe|Traficante, Antonio|Cittadini, Achille
PMID: 19031937
Journal: Pharmacogenomics J. 2008 Aug;8(4):278-88.
Title: Pharmacogenetic profiling in patients with advanced colorectal cancer treated with first-line FOLFIRI chemotherapy.
Author: Ruzzo, A|Graziano, F|Loupakis, F|Santini, D|Catalano, V|Bisonni, R|Ficarelli, R|Fontana, A|Andreoni, F|Falcone, A|Canestrari, E|Tonini, G|Mari, D|Lippe, P|Pizzagalli, F|Schiavon, G|Alessandroni, P|Giustini, L|Maltese, P|Testa, E|Menichetti, E T|Magnani, M
PMID: 17549067
Journal: J Psychosom Res. 2009 Mar;66(3):259-66.
Title: The level of oxidative stress and the expression of genes involved in DNA-damage signaling pathways in depressive patients with colorectal carcinoma.
Author: Wei, Yong-chang|Zhou, Fu-ling|He, Da-lin|Bai, Ji-rong|Hui, Ling-yun|Wang, Xin-yang|Nan, Ke-jun
PMID: 19232240
Journal: Int J Colorectal Dis. 2010 Feb;25(2):169-80.
Title: A meta-analysis on XRCC1 and XRCC3 polymorphisms and colorectal cancer risk.
Author: Jiang, Zheng|Li, Chunxiang|Xu, Ye|Cai, Sanjun
PMID: 19915856
Journal: J Cancer Res Clin Oncol. 2010 Oct;136(10):1517-25.
Title: Polymorphisms in DNA repair genes XRCC1, XRCC3 and XPD, and colorectal cancer risk: a case-control study in an Indian population.
Author: Wang, Jingwen|Zhao, Yang|Jiang, Jing|Gajalakshmi, Vendhan|Kuriki, Kiyonori|Nakamura, Seiichi|Akasaka, Susumu|Ishikawa, Hideki|Suzuki, Sadao|Nagaya, Teruo|Tokudome, Shinkan
PMID: 20229274
Journal: Oncol Rep. 2010 Jul;24(1):37-46.
Title: Aspirin and alterations in DNA repair proteins in the SW480 colorectal cancer cell line.
Author: Dibra, H K|Brown, J E|Hooley, P|Nicholl, I D
PMID: 20514442
Journal: Pharmacogenomics J. 2011 Jun;11(3):214-26.
Title: Tumor response is predicted by patient genetic profile in rectal cancer patients treated with neo-adjuvant chemo-radiotherapy.
Author: Cecchin, E|Agostini, M|Pucciarelli, S|De Paoli, A|Canzonieri, V|Sigon, R|De Mattia, E|Friso, M L|Biason, P|Visentin, M|Nitti, D|Toffoli, G
PMID: 20368715
Journal: Mol Biol Rep. 2011 Apr;38(4):2849-54.
Title: Polymorphisms in RAD51, XRCC2 and XRCC3 genes of the homologous recombination repair in colorectal cancer--a case control study.
Author: Krupa, Renata|Sliwinski, Tomasz|Wisniewska-Jarosinska, Maria|Chojnacki, Jan|Wasylecka, Maja|Dziki, Lukasz|Morawiec, Jan|Blasiak, Janusz
PMID: 21104022
Journal: Curr Med Res Opin. 2011 Jul;27(7):1295-302.
Title: Association of APE1 and hOGG1 polymorphisms with colorectal cancer risk in a Turkish population.
Author: Canbay, Emel|Cakmakoglu, Bedia|Zeybek, Umit|Sozen, Seyma|Cacina, Canan|Gulluoglu, Mine|Balik, Emre|Bulut, Turker|Yamaner, Sumer|Bugra, Dursun
PMID: 21561390
Journal: Hepatogastroenterology. 2012 Jun;59(116):977-80.
Title: Prediction of genetic polymorphisms of DNA repair genes XRCC1 and XRCC3 in the survival of colorectal cancer receiving chemotherapy in the Chinese population.
Author: Liu, Yang|Chen, Haihui|Chen, Limin|Hu, Chunhong
PMID: 22580644
Journal: Asian Pac J Cancer Prev. 2012;13(2):665-9.
Title: Genetic polymorphisms of DNA repair genes XRCC1 and XRCC3 and risk of colorectal cancer in Chinese population.
Author: Zhao, Yi|Deng, Xin|Wang, Zhen|Wang, Qiang|Liu, Yixia
PMID: 22524842
Journal: Mol Biol Rep. 2012 Jan;39(1):527-34.
Title: The C/A polymorphism in intron 11 of the XPC gene plays a crucial role in the modulation of an individual's susceptibility to sporadic colorectal cancer.
Author: Gil, Justyna|Ramsey, Dave|Stembalska, Agnieszka|Karpinski, Pawel|Pesz, Karolina A|Laczmanska, Izabela|Leszczynski, Przemyslaw|Grzebieniak, Zygmunt|Sasiadek, Maria Malgorzata
PMID: 21559836
Journal: Cancer Epidemiol. 2012 Apr;36(2):183-9.
Title: DNA repair gene polymorphisms and risk of early onset colorectal cancer in Lynch syndrome.
Author: Reeves, Stuart G|Meldrum, Cliff|Groombridge, Claire|Spigelman, Allan|Suchy, Janina|Kurzawski, Grzegorz|Lubinski, Jan|Scott, Rodney J
PMID: 21974800
Journal: Pharmacogenomics J. 2013 Oct;13(5):403-9.
Title: A prospective validation pharmacogenomic study in the adjuvant setting of colorectal cancer patients treated with the 5-fluorouracil/leucovorin/oxaliplatin (FOLFOX4) regimen.
Author: Cecchin, E|D'Andrea, M|Lonardi, S|Zanusso, C|Pella, N|Errante, D|De Mattia, E|Polesel, J|Innocenti, F|Toffoli, G
PMID: 22868256
Journal: Mol Biol Rep. 2013 Jun;40(6):3943-52.
Title: Association between XRCC1 and XRCC3 polymorphisms and colorectal cancer risk: a meta-analysis of 23 case-control studies.
Author: Liu, Li|Miao, Lin|Ji, Guozhong|Qiang, Fulin|Liu, Zheng|Fan, Zhining
PMID: 23271134
Journal: Tumour Biol. 2013 Jun;34(3):1421-9.
Title: Association between XRCC3 Thr241Met polymorphism and colorectal cancer risk.
Author: Wang, ZhiZhen|Zhang, Wencheng
PMID: 23504553
Journal: Gene. 2013 Jul 1;523(1):10-9.
Title: Association between the XRCC3 T241M polymorphism and risk of cancer: evidence from 157 case-control studies.
Author: He, Xiao-Feng|Wei, Wu|Li, Jia-Lin|Shen, Xu-Liang|Ding, Da-peng|Wang, Su-Lan|Liu, Zhi-Zhong|Qin, Jiang-Bo|Wu, Li-Xia|Xie, Dao-Lin
PMID: 23562721
Journal: PLoS One. 2013 Jul 23;8(7):e69039.
Title: Tumor site- and stage-specific associations between allelic variants of glutathione S-transferase and DNA-repair genes and overall survival in colorectal cancer patients receiving 5-fluorouracil-based chemotherapy.
Author: Lai, Ching-Yu|Hsieh, Ling-Ling|Sung, Fung-Chang|Tang, Reiping|Bai, Chyi-Huey|Wu, Fang-Yang|Chiou, Hung-Yi|Yeh, Chih-Ching
PMID: 23894404
Journal: Pol J Pathol. 2013 Oct;64(3):185-90.
Title: Association of Thr241Met polymorphism of XRCC3 gene with risk of colorectal cancer in the Polish population.
Author: Mucha, Bartosz|Przybylowska-Sygut, Karolina|Dziki, Adam Janusz|Dziki, Lukasz|Sygut, Andrzej|Majsterek, Ireneusz
PMID: 24166604
Journal: Asian Pac J Cancer Prev. 2013;14(10):5609-14.
Title: Genes and SNPs associated with non-hereditary and hereditary colorectal cancer.
Author: Nassiri, Mohammadreza|Kooshyar, Mohammad Mahdi|Roudbar, Zahra|Mahdavi, Morteza|Doosti, Mohammad
PMID: 24289550
Journal: BMC Cancer. 2014 Nov 24;14:875.
Title: Phase 1/2 study of valproic acid and short-course radiotherapy plus capecitabine as preoperative treatment in low-moderate risk rectal cancer-V-shoRT-R3 (Valproic acid--short Radiotherapy--rectum 3rd trial).
Author: Avallone, Antonio|Piccirillo, Maria Carmela|Delrio, Paolo|Pecori, Biagio|Di Gennaro, Elena|Aloj, Luigi|Tatangelo, Fabiana|D'Angelo, Valentina|Granata, Cinzia|Cavalcanti, Ernesta|Maurea, Nicola|Maiolino, Piera|Bianco, Franco|Montano, Massimo|Silvestro, Luc
PMID: 25421252
Journal: Asian Pac J Cancer Prev. 2014;15(22):9621-5.
Title: XRCC3 Thr241Met gene polymorphism and risk of colorectal cancer in Kashmir: a case control study.
Author: Nissar, Saniya|Sameer, Aga Syed|Lone, Tufail A|Chowdri, Nissar A|Rasool, Roohi
PMID: 25520078
Journal: Sci Rep. 2014 Nov 5;4:6828.
Title: Genetic markers for toxicity of adjuvant oxaliplatin and fluoropyrimidines in the phase III TOSCA trial in high-risk colon cancer patients.
Author: Ruzzo, Annamaria|Graziano, Francesco|Galli, Fabio|Giacomini, Elisa|Floriani, Irene|Galli, Francesca|Rulli, Eliana|Lonardi, Sara|Ronzoni, Monica|Massidda, Bruno|Zagonel, Vittorina|Pella, Nicoletta|Mucciarini, Claudia|Labianca, Roberto|Ionta, Maria Teresa|V
PMID: 25370899
Journal: Med Oncol. 2014 Jul;31(7):72.
Title: CYP1A1 Ile462Val polymorphism and colorectal cancer risk in Polish patients.
Author: Gil, Justyna|Gaj, Pawel|Misiak, Blazej|Ostrowski, Jerzy|Karpinski, Pawel|Jarczynska, Alicja|Kielan, Wojciech|Sasiadek, Maria Malgorzata
PMID: 24939416
Journal: Med Oncol. 2014 May;31(5):942.
Title: No association between XRCC3 Thr241Met and XPD Lys751Gln polymorphisms and the risk of colorectal cancer in West Algerian population: a case-control study.
Author: Moghtit, Fatima Zohra|Aberkane, Meriem Samia|Le Morvan, Valerie|Louhibi, Lotfi|Bellot, Ricardo|Bousahba, Abdelkader|Megaiz, Ahlem|Fodil, Mostefa|Mediene-Benchekor, Sounnia|Zemani-Fodil, Faouzia|Boudjema, Abdallah|Robert, Jacques|Saidi-Mehtar, Nadhira
PMID: 24687779
Journal: Clin Cancer Res. 2015 Apr 1;21(7):1583-90.
Title: Pharmacogenetic Analysis of INT 0144 Trial: Association of Polymorphisms with Survival and Toxicity in Rectal Cancer Patients Treated with 5-FU and Radiation.
Author: Bohanes, Pierre|Rankin, Cathryn J|Blanke, Charles D|Winder, Thomas|Ulrich, Cornelia M|Smalley, Stephen R|Rich, Tyvin A|Martensen, James A|Benson, Al B 3rd|Mayer, Robert J|Cripps, Christine M|Danenberg, Kathleen|Makar, Karen W|Zhang, Wu|Benedetti, Jacqueli
PMID: 25589620
Journal: Cancer Chemother Pharmacol. 2015 Apr;75(4):763-72.
Title: Germline TYMS genotype is highly predictive in patients with metastatic gastrointestinal malignancies receiving capecitabine-based chemotherapy.
Author: Joerger, M|Huitema, A D R|Boot, H|Cats, A|Doodeman, V D|Smits, P H M|Vainchtein, L|Rosing, H|Meijerman, I|Zueger, M|Meulendijks, D|Cerny, T D|Beijnen, J H|Schellens, J H M
PMID: 25677447
Journal: Asian Pac J Cancer Prev. 2015;16(2):713-8.
Title: DNA repair gene polymorphisms do not predict response to radiotherapy-based multimodality treatment of patients with rectal cancer: a meta-analysis.
Author: Guo, Cheng-Xian|Yang, Guo-Ping|Pei, Qi|Yin, Ji-Ye|Tan, Hong-Yi|Yuan, Hong
PMID: 25684513
Journal: Asian Pac J Cancer Prev. 2015;16(6):2263-8.
Title: Association between the XRCC3 Thr241Met polymorphism and risk of colorectal cancer: a meta analysis of 5,193 cases and 6,645 controls.
Author: Namazi, Abolfazl|Abedinzadeh, Maryam|Nourbaksh, Parisa|Neamatzadeh, Hossein
PMID: 25824748
Journal: Cancer Biol Ther. 2015;16(8):1160-71.
Title: A functional biological network centered on XRCC3: a new possible marker of chemoradiotherapy resistance in rectal cancer patients.
Author: Agostini, Marco|Zangrando, Andrea|Pastrello, Chiara|D'Angelo, Edoardo|Romano, Gabriele|Giovannoni, Roberto|Giordan, Marco|Maretto, Isacco|Bedin, Chiara|Zanon, Carlo|Digito, Maura|Esposito, Giovanni|Mescoli, Claudia|Lavitrano, Marialuisa|Rizzolio, Flavio|J
PMID: 26023803
Journal: Genet Mol Res. 2015 Nov 23;14(4):14831-9.
Title: Meta-analysis of the relationship between XRCC3 T241M polymorphism and colorectal cancer susceptibility.
Author: Zhang, L Z|Li, Y S|Liu, H Z
PMID: 26600544
Journal: Asian Pac J Cancer Prev. 2016 Nov 1;17(11):4803-4804.
Title: Comment on: "Association Between the XRCC3 Thr241Met Polymorphism and Risk of Colorectal Cancer: A Meta-Analysis of 5,193 Cases and 6,645 Controls"
Author: Sahami-Fard, Mohammad Hossein|Farashahi Yazd, Ehsan
PMID: 28030902
Journal: Am J Clin Oncol. 2017 Dec;40(6):535-542.
Title: Potential Role of Single Nucleotide Polymorphisms of XRCC1, XRCC3, and RAD51 in Predicting Acute Toxicity in Rectal Cancer Patients Treated With Preoperative Radiochemotherapy.
Author: Osti, Mattia F|Nicosia, Luca|Agolli, Linda|Gentile, Giovanna|Falco, Teresa|Bracci, Stefano|Di Nardo, Francesco|Minniti, Giuseppe|De Sanctis, Vitaliana|Valeriani, Maurizio|Maglio, Marianna|Borro, Marina|Simmaco, Maurizio|Enrici, Riccardo M
PMID: 25811296
Journal: Clin Lab. 2017 Apr 1;63(4):647-658.
Title: Colorectal Cancer Carcinogenesis: a Multivariate Genetic Model in a Cohort of Romanian Population.
Author: Procopciuc, Lucia M|Osian, Gelu|Iancu, Mihaela
PMID: 28397463
Journal: PLoS One. 2018 Feb 2;13(2):e0192316.
Title: XRCC3 Thr241Met and TYMS variable number tandem repeat polymorphisms are associated with time-to-metastasis in colorectal cancer.
Author: He, Yanjing|Penney, Michelle E|Negandhi, Amit A|Parfrey, Patrick S|Savas, Sevtap|Yilmaz, Yildiz E
PMID: 29394274