Primary Site >> Colorectal Cancer

Gene >> XRCC3

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Ref: Nonconservative amino acid substitution variants exist at polymorphic frequency in DNA repair genes in healthy humans.
PMID: 9485007
Ref: Lack of involvement of nucleotide excision repair gene polymorphisms in colorectal cancer.
PMID: 12865926
Ref: An association of polymorphism of DNA repair genes XRCC1 and XRCC3 with colorectal cancer.
PMID: 15354414
Ref: Polymorphisms of the XRCC1, XRCC3, & XPD genes, and colorectal cancer risk: a case-control study in Taiwan.
PMID: 15679883
Ref: MS-920: DNA repair gene polymorphisms, diet and colorectal cancer risk in Taiwan.
PMID: 15914278
Ref: The association of the DNA repair gene XRCC3 Thr241Met polymorphism with susceptibility to colorectal cancer in a Chinese population.
PMID: 16271954
Ref: Polymorphisms of the XRCC1, XRCC3 and XPD genes and risk of colorectal adenoma and carcinoma, in a Norwegian cohort: a case control study.
PMID: 16542436
Ref: Polymorphisms in genes of nucleotide and base excision repair: risk and prognosis of colorectal cancer.
PMID: 16609022
Ref: Haploinsufficiency of RAD51B causes centrosome fragmentation and aneuploidy in human cells.
PMID: 16778173
Ref: Association between polymorphisms of biotransformation and DNA-repair genes and risk of colorectal cancer in Taiwan.
PMID: 17191090
Ref: Pharmacogenetic profiling in patients with advanced colorectal cancer treated with first-line FOLFIRI chemotherapy.
PMID: 17549067
Ref: Pharmacogenetic approach for capecitabine or 5-fluorouracil selection to be combined with oxaliplatin as first-line chemotherapy in advanced colorectal cancer.
PMID: 18448328
Ref: Polymorphisms of the DNA repair genes XRCC1 and XRCC3 and risk of lung and colorectal cancer: a case-control study in a Southern Italian population.
PMID: 19031937
Ref: The level of oxidative stress and the expression of genes involved in DNA-damage signaling pathways in depressive patients with colorectal carcinoma.
PMID: 19232240
Ref: A meta-analysis on XRCC1 and XRCC3 polymorphisms and colorectal cancer risk.
PMID: 19915856
Ref: Polymorphisms in DNA repair genes XRCC1, XRCC3 and XPD, and colorectal cancer risk: a case-control study in an Indian population.
PMID: 20229274
Ref: Aspirin and alterations in DNA repair proteins in the SW480 colorectal cancer cell line.
PMID: 20514442
Ref: Tumor response is predicted by patient genetic profile in rectal cancer patients treated with neo-adjuvant chemo-radiotherapy.
PMID: 20368715
Ref: Polymorphisms in RAD51, XRCC2 and XRCC3 genes of the homologous recombination repair in colorectal cancer--a case control study.
PMID: 21104022
Ref: Association of APE1 and hOGG1 polymorphisms with colorectal cancer risk in a Turkish population.
PMID: 21561390
Ref: The C/A polymorphism in intron 11 of the XPC gene plays a crucial role in the modulation of an individual's susceptibility to sporadic colorectal cancer.
PMID: 21559836
Ref: DNA repair gene polymorphisms and risk of early onset colorectal cancer in Lynch syndrome.
PMID: 21974800
Ref: Genetic polymorphisms of DNA repair genes XRCC1 and XRCC3 and risk of colorectal cancer in Chinese population.
PMID: 22524842
Ref: Prediction of genetic polymorphisms of DNA repair genes XRCC1 and XRCC3 in the survival of colorectal cancer receiving chemotherapy in the Chinese population.
PMID: 22580644
Ref: A prospective validation pharmacogenomic study in the adjuvant setting of colorectal cancer patients treated with the 5-fluorouracil/leucovorin/oxaliplatin (FOLFOX4) regimen.
PMID: 22868256
Ref: Association between XRCC1 and XRCC3 polymorphisms and colorectal cancer risk: a meta-analysis of 23 case-control studies.
PMID: 23271134
Ref: Association between XRCC3 Thr241Met polymorphism and colorectal cancer risk.
PMID: 23504553
Ref: Association between the XRCC3 T241M polymorphism and risk of cancer: evidence from 157 case-control studies.
PMID: 23562721
Ref: Tumor site- and stage-specific associations between allelic variants of glutathione S-transferase and DNA-repair genes and overall survival in colorectal cancer patients receiving 5-fluorouracil-based chemotherapy.
PMID: 23894404
Ref: Association of Thr241Met polymorphism of XRCC3 gene with risk of colorectal cancer in the Polish population.
PMID: 24166604
Ref: Genes and SNPs associated with non-hereditary and hereditary colorectal cancer.
PMID: 24289550
Ref: No association between XRCC3 Thr241Met and XPD Lys751Gln polymorphisms and the risk of colorectal cancer in West Algerian population: a case-control study.
PMID: 24687779
Ref: CYP1A1 Ile462Val polymorphism and colorectal cancer risk in Polish patients.
PMID: 24939416
Ref: Genetic markers for toxicity of adjuvant oxaliplatin and fluoropyrimidines in the phase III TOSCA trial in high-risk colon cancer patients.
PMID: 25370899
Ref: Phase 1/2 study of valproic acid and short-course radiotherapy plus capecitabine as preoperative treatment in low-moderate risk rectal cancer-V-shoRT-R3 (Valproic acid--short Radiotherapy--rectum 3rd trial).
PMID: 25421252
Ref: XRCC3 Thr241Met gene polymorphism and risk of colorectal cancer in Kashmir: a case control study.
PMID: 25520078
Ref: Pharmacogenetic Analysis of INT 0144 Trial: Association of Polymorphisms with Survival and Toxicity in Rectal Cancer Patients Treated with 5-FU and Radiation.
PMID: 25589620
Ref: Germline TYMS genotype is highly predictive in patients with metastatic gastrointestinal malignancies receiving capecitabine-based chemotherapy.
PMID: 25677447
Ref: DNA repair gene polymorphisms do not predict response to radiotherapy-based multimodality treatment of patients with rectal cancer: a meta-analysis.
PMID: 25684513
Ref: Association between the XRCC3 Thr241Met polymorphism and risk of colorectal cancer: a meta analysis of 5,193 cases and 6,645 controls.
PMID: 25824748
Ref: A functional biological network centered on XRCC3: a new possible marker of chemoradiotherapy resistance in rectal cancer patients.
PMID: 26023803
Ref: Meta-analysis of the relationship between XRCC3 T241M polymorphism and colorectal cancer susceptibility.
PMID: 26600544
Ref: Comment on: "Association Between the XRCC3 Thr241Met Polymorphism and Risk of Colorectal Cancer: A Meta-Analysis of 5,193 Cases and 6,645 Controls"
PMID: 28030902
Ref: Potential Role of Single Nucleotide Polymorphisms of XRCC1, XRCC3, and RAD51 in Predicting Acute Toxicity in Rectal Cancer Patients Treated With Preoperative Radiochemotherapy.
PMID: 25811296
Ref: Colorectal Cancer Carcinogenesis: a Multivariate Genetic Model in a Cohort of Romanian Population.
PMID: 28397463
Ref: XRCC3 Thr241Met and TYMS variable number tandem repeat polymorphisms are associated with time-to-metastasis in colorectal cancer.
PMID: 29394274