Primary Site >> Colorectal Cancer

Gene >> XPO1

Journal: Proc Natl Acad Sci U S A. 2000 Oct 24;97(22):12085-90.
Title: Adenomatous polyposis coli protein contains two nuclear export signals and shuttles between the nucleus and cytoplasm.
Author: Neufeld, K L|Nix, D A|Bogerd, H|Kang, Y|Beckerle, M C|Cullen, B R|White, R L
PMID: 11035805
Journal: Nat Cell Biol. 2000 Sep;2(9):653-60.
Title: Nuclear-cytoplasmic shuttling of APC regulates beta-catenin subcellular localization and turnover.
Author: Henderson, B R
PMID: 10980707
Journal: Carcinogenesis. 2001 Jun;22(6):957-64.
Title: Deoxycholic acid suppresses p53 by stimulating proteasome-mediated p53 protein degradation.
Author: Qiao, D|Gaitonde, S V|Qi, W|Martinez, J D
PMID: 11375905
Journal: J Biol Chem. 2001 Oct 26;276(43):40113-9. Epub 2001 Jul 26.
Title: Suppressor of fused negatively regulates beta-catenin signaling.
Author: Meng, X|Poon, R|Zhang, X|Cheah, A|Ding, Q|Hui, C C|Alman, B
PMID: 11477086
Journal: J Biol Chem. 2002 Jul 5;277(27):24258-64. Epub 2002 May 1.
Title: Lymphoid enhancer factor-1 blocks adenomatous polyposis coli-mediated nuclear export and degradation of beta-catenin. Regulation by histone deacetylase 1.
Author: Henderson, Beric R|Galea, Melanie|Schuechner, Stefan|Leung, Louie
PMID: 11986304
Journal: J Biol Chem. 2003 Jan 31;278(5):2773-6. Epub 2002 Dec 4.
Title: Leptomycin B, an inhibitor of the nuclear export receptor CRM1, inhibits COX-2 expression.
Author: Jang, Byeong-Churl|Munoz-Najar, Ursula|Paik, Ji-Hye|Claffey, Kevin|Yoshida, Minoru|Hla, Timothy
PMID: 12468543
Journal: EMBO Rep. 2005 Feb;6(2):184-90.
Title: Redefining the subcellular location and transport of APC: new insights using a panel of antibodies.
Author: Brocardo, Mariana|Nathke, Inke S|Henderson, Beric R
PMID: 15678162
Journal: Cell Biol Int. 2006 Mar;30(3):253-61. Epub 2005 Dec 27.
Title: Overexpressed LEF-1 proteins display different nuclear localization patterns of beta-catenin in normal versus tumor cells.
Author: Ki, Hyunkyoung|Jung, Ho-Chul|Park, Jae-Hyo|Kim, Jin-Sook|Lee, Kwang Youl|Kim, Tae Sung|Kim, Kwonseop
PMID: 16378739
Journal: FASEB J. 2007 Jan;21(1):207-16. Epub 2006 Nov 10.
Title: Nuclear export is essential for the tumor-promoting activity of survivin.
Author: Knauer, Shirley K|Kramer, Oliver H|Knosel, Thomas|Engels, Knut|Rodel, Franz|Kovacs, Adorjan F|Dietmaier, Wolfgang|Klein-Hitpass, Ludger|Habtemichael, Negusse|Schweitzer, Andrea|Brieger, Jurgen|Rodel, Claus|Mann, Wolf|Petersen, Iver|Heinzel, Thorsten|Staub
PMID: 17099069
Journal: J Biol Chem. 2008 Nov 14;283(46):31991-2002.
Title: SUMOylation regulates nuclear localization of Kruppel-like factor 5.
Author: Du, James X|Bialkowska, Agnieszka B|McConnell, Beth B|Yang, Vincent W
PMID: 18782761
Journal: Adv Exp Med Biol. 2009;656:13-29.
Title: Nuclear APC.
Author: Neufeld, Kristi L
PMID: 19928349
Journal: Oncogene. 2012 May 24;31(21):2653-67.
Title: Inhibition of beta-catenin signaling by nongenomic action of orphan nuclear receptor Nur77.
Author: Sun, Z|Cao, X|Jiang, M-M|Qiu, Y|Zhou, H|Chen, L|Qin, B|Wu, H|Jiang, F|Chen, J|Liu, J|Dai, Y|Chen, H-F|Hu, Q-Y|Wu, Z|Zeng, J-Z|Yao, X-S|Zhang, X-K
PMID: 21986938
Journal: Cancer Biol Ther. 2015;16(7):1110-8.
Title: Novel reversible selective inhibitor of nuclear export shows that CRM1 is a target in colorectal cancer cells.
Author: Niu, Mingshan|Chong, Yulong|Han, Yan|Liu, Xuejiao
PMID: 25996664
Journal: Clin Cancer Res. 2016 Apr 1;22(7):1663-73.
Title: XPO1 Inhibition Enhances Radiation Response in Preclinical Models of Rectal Cancer.
Author: Ferreiro-Neira, Isabel|Torres, Nancy E|Liesenfeld, Lukas F|Chan, Carlos H F|Penson, Tristan|Landesman, Yosef|Senapedis, William|Shacham, Sharon|Hong, Theodore S|Cusack, James C
PMID: 26603256
Journal: Mol Biol Cell. 2016 Apr 15;27(8):1346-57.
Title: RCC1-dependent activation of Ran accelerates cell cycle and DNA repair, inhibiting DNA damage-induced cell senescence.
Author: Cekan, Pavol|Hasegawa, Keisuke|Pan, Yu|Tubman, Emily|Odde, David|Chen, Jin-Qiu|Herrmann, Michelle A|Kumar, Sheetal|Kalab, Petr
PMID: 26864624
Journal: Free Radic Biol Med. 2016 Jun;95:121-32.
Title: Cytoplasmic localization of Nrf2 promotes colorectal cancer with more aggressive tumors via upregulation of PSMD4.
Author: Lin, Po-Lin|Chang, Jinghua Tsai|Wu, De-Wei|Huang, Chi-Chou|Lee, Huei
PMID: 27033953
Journal: Strahlenther Onkol. 2016 Dec;192(12):961-962.
Title: [Radiation response enhanced by inhibition of XPO1 in preclinical rectal cancer models].
Author: von Fallois, Moritz|Depping, Reinhard
PMID: 27757501
Journal: Mol Cancer Ther. 2017 Apr;16(4):717-728.
Title: Nuclear Export of Ubiquitinated Proteins Determines the Sensitivity of Colorectal Cancer to Proteasome Inhibitor.
Author: Wu, Tingyu|Chen, Wei|Zhong, Yongwang|Hou, Xiaodan|Fang, Shengyun|Liu, Chen-Ying|Wang, Guanghui|Yu, Tong|Huang, Yu-Yang|Ouyang, Xuesong|Li, Henry Q X|Cui, Long|Yang, Yili
PMID: 27903750
Journal: Onco Targets Ther. 2017 Jul 17;10:3501-3513.
Title: Nuclear DDX3 expression predicts poor outcome in colorectal and breast cancer.
Author: Heerma van Voss, Marise R|Vesuna, Farhad|Bol, Guus M|Meeldijk, Jan|Raman, Ana|Offerhaus, G Johan|Buerger, Horst|Patel, Arvind H|van der Wall, Elsken|van Diest, Paul J|Raman, Venu
PMID: 28761359
Journal: Sci Rep. 2017 Nov 3;7(1):14979.
Title: L290P/V mutations increase ERK3's cytoplasmic localization and migration/invasion-promoting capability in cancer cells.
Author: Alsaran, Hadel|Elkhadragy, Lobna|Shakya, Astha|Long, Weiwen
PMID: 29101390