Primary Site >> Colorectal Cancer

Gene >> XIAP

Journal: Clin Cancer Res. 2001 Dec;7(12):4209-19.
Title: Augmentation of apoptosis and tumor regression by flavopiridol in the presence of CPT-11 in Hct116 colon cancer monolayers and xenografts.
Author: Motwani, M|Jung, C|Sirotnak, F M|She, Y|Shah, M A|Gonen, M|Schwartz, G K
PMID: 11751522
Journal: Gene Ther. 2002 Sep;9(18):1262-70.
Title: Mechanisms involved in development of resistance to adenovirus-mediated proapoptotic gene therapy in DLD1 human colon cancer cell line.
Author: Zhang, L|Gu, J|Lin, T|Huang, X|Roth, J A|Fang, B
PMID: 12215894
Journal: Neoplasia. 2002 Nov-Dec;4(6):551-7.
Title: Defining characteristics of Types I and II apoptotic cells in response to TRAIL.
Author: Ozoren, Nesrin|El-Deiry, Wafik S
PMID: 12407450
Journal: Cancer Res. 2003 Aug 15;63(16):5118-25.
Title: Rottlerin sensitizes colon carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis via uncoupling of the mitochondria independent of protein kinase C.
Author: Tillman, David M|Izeradjene, Kamel|Szucs, Kinga Szekely|Douglas, Leslie|Houghton, Janet A
PMID: 12941843
Journal: J Biol Chem. 2003 Dec 19;278(51):51091-9. Epub 2003 Oct 3.
Title: Induction of cIAP-2 in human colon cancer cells through PKC delta/NF-kappa B.
Author: Wang, Qingding|Wang, Xiaofu|Evers, B Mark
PMID: 14527959
Journal: Cancer Res. 2003 Oct 15;63(20):6815-24.
Title: Coexistence of high levels of apoptotic signaling and inhibitor of apoptosis proteins in human tumor cells: implication for cancer specific therapy.
Author: Yang, Lily|Cao, Zehong|Yan, Hui|Wood, William C
PMID: 14583479
Journal: Cancer Immunol Immunother. 2004 Sep;53(9):770-6. Epub 2004 May 11.
Title: Expression of IAP family proteins in colon cancers from patients with different age groups.
Author: Endo, T|Abe, S|Seidlar, H B K|Nagaoka, S|Takemura, T|Utsuyama, M|Kitagawa, M|Hirokawa, K
PMID: 15138717
Journal: Carcinogenesis. 2004 Oct;25(10):1813-20.
Title: Sodium butyrate sensitizes TRAIL-mediated apoptosis by induction of transcription from the DR5 gene promoter through Sp1 sites in colon cancer cells.
Author: Kim, Young-Ho|Park, Jong-Wook|Lee, Jai-Youl|Kwon, Taeg Kyu
PMID: 15142888
Journal: Jpn J Clin Oncol. 2004 Oct;34(10):584-7.
Title: Diffuse expression of hRFI is correlated with blood vessel invasion in gastric carcinoma.
Author: Sasaki, Shin|Kitayama, Joji|Watanabe, Toshiaki|Konishi, Tsuyoshi|Nagawa, Hirokazu
PMID: 15591455
Journal: Cancer Res. 2004 Dec 15;64(24):9105-14.
Title: Elimination of hepatic metastases of colon cancer cells via p53-independent cross-talk between irinotecan and Apo2 ligand/TRAIL.
Author: Ravi, Rajani|Jain, Ajay J|Schulick, Richard D|Pham, Vui|Prouser, Traci S|Allen, Heather|Mayer, Elizabeth Garrett|Yu, Hua|Pardoll, Drew M|Ashkenazi, Avi|Bedi, Atul
PMID: 15604280
Journal: Clin Cancer Res. 2004 Dec 15;10(24):8284-92.
Title: Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis is inhibited by Bcl-2 but restored by the small molecule Bcl-2 inhibitor, HA 14-1, in human colon cancer cells.
Author: Sinicrope, Frank A|Penington, Robert C|Tang, Xi Ming
PMID: 15623604
Journal: Drug Resist Updat. 2004 Dec;7(6):345-58.
Title: Lessons from TRAIL-resistance mechanisms in colorectal cancer cells: paving the road to patient-tailored therapy.
Author: Van Geelen, Caroline M M|de Vries, Elisabeth G E|de Jong, Steven
PMID: 15790545
Journal: Chin J Dig Dis. 2005;6(1):10-4.
Title: Low expression of XIAP-associated factor 1 in human colorectal cancers.
Author: Ma, Tian Le|Ni, Pei Hua|Zhong, Jie|Tan, Ji Hong|Qiao, Min Min|Jiang, Shi Hu
PMID: 15667552
Journal: Oncogene. 2005 Mar 17;24(12):2050-8.
Title: Casein kinase II (CK2) enhances death-inducing signaling complex (DISC) activity in TRAIL-induced apoptosis in human colon carcinoma cell lines.
Author: Izeradjene, Kamel|Douglas, Leslie|Delaney, Addison|Houghton, Janet A
PMID: 15688023
Journal: Korean J Gastroenterol. 2005 Apr;45(4):285-93.
Title: [Frequent epigenetic inactivation of XAF1 by promotor hypermethylation in human colon cancers].
Author: Jang, Jae Young|Kim, Hyo Jong|Chi, Sung-Gil|Lee, Kil Yeon|Nam, Ki Deuk|Kim, Nam Hoon|Lee, Sang Kil|Joo, Kwang Ro|Dong, Seok Ho|Kim, Byung-Ho|Chang, Young Woon|Lee, Joung Il|Chang, Rin
PMID: 15843754
Journal: Biochem Pharmacol. 2005 Aug 15;70(4):580-9.
Title: 17-Allylamino-17-demethoxygeldanamycin overcomes TRAIL resistance in colon cancer cell lines.
Author: Vasilevskaya, Irina A|O'Dwyer, Peter J
PMID: 15993848
Journal: Cell Cycle. 2005 Sep;4(9):1201-15.
Title: Molecular targets and anticancer potential of indole-3-carbinol and its derivatives.
Author: Aggarwal, Bharat B|Ichikawa, Haruyo
PMID: 16082211
Journal: Clin Cancer Res. 2005 Nov 1;11(21):7621-8.
Title: X-Linked inhibitor of apoptosis protein expression level in colorectal cancer is regulated by hepatocyte growth factor/C-met pathway via Akt signaling.
Author: Takeuchi, Hiroya|Kim, Joseph|Fujimoto, Akihide|Umetani, Naoyuki|Mori, Takuji|Bilchik, Anton|Turner, Rod|Tran, Andy|Kuo, Christine|Hoon, Dave S B
PMID: 16278380
Journal: Carcinogenesis. 2006 Jun;27(6):1285-91. Epub 2006 Feb 23.
Title: Overexpression of p65/RelA potentiates curcumin-induced apoptosis in HCT116 human colon cancer cells.
Author: Collett, Gavin P|Campbell, Frederick C
PMID: 16497702
Journal: Apoptosis. 2006 Mar;11(3):401-11.
Title: Pioglitazone, a synthetic ligand for PPARgamma, induces apoptosis in RB-deficient human colorectal cancer cells.
Author: Lee, C J|Han, J S|Seo, C Y|Park, T H|Kwon, H C|Jeong, J S|Kim, I H|Yun, J|Bae, Y S|Kwak, J Y|Park, J I
PMID: 16520894
Journal: Gastroenterology. 2006 Mar;130(3):747-58.
Title: All-trans retinoic acid induces XAF1 expression through an interferon regulatory factor-1 element in colon cancer.
Author: Wang, Jide|Peng, Ying|Sun, Yun Wei|He, Hua|Zhu, Senlin|An, Xiaomeng|Li, Ming|Lin, Marie C M|Zou, Bing|Xia, Harry Hua-Xiang|Jiang, Bo|Chan, Annie O O|Yuen, Man Fung|Kung, Hsiang Fu|Wong, Benjamin C Y
PMID: 16530516
Journal: Apoptosis. 2006 Oct;11(10):1801-11.
Title: PPARgamma is a key target of butyrate-induced caspase-3 activation in the colorectal cancer cell line Caco-2.
Author: Schwab, Markus|Reynders, Veerle|Ulrich, Sandra|Zahn, Nadine|Stein, Jurgen|Schroder, Oliver
PMID: 16927016
Journal: Pathol Oncol Res. 2006;12(3):133-42. Epub 2006 Sep 23.
Title: Proteasome inhibitors sensitize colon carcinoma cells to TRAIL-induced apoptosis via enhanced release of Smac/DIABLO from the mitochondria.
Author: Nagy, Katalin|Szekely-Szuts, Kinga|Izeradjene, Kamel|Douglas, Leslie|Tillman, Mike|Barti-Juhasz, Helga|Dominici, Massimo|Spano, Carlotta|Luca Cervo, Gian|Conte, Pierfranco|Houghton, Janet A|Mihalik, Rudolf|Kopper, Laszlo|Petak, Istvan
PMID: 16998592
Journal: Gastroenterology. 2006 Dec;131(6):1835-43. Epub 2006 Oct 1.
Title: Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers.
Author: Zou, Bing|Chim, Chor Sang|Zeng, Hui|Leung, Suet Yi|Yang, Yi|Tu, Shui Ping|Lin, Marie C M|Wang, Jide|He, Hua|Jiang, Shi Hu|Sun, Yun Wei|Yu, Li Fen|Yuen, Siu Tsan|Kung, Hsiang Fu|Wong, Benjamin C Y
PMID: 17087954
Journal: Cancer Gene Ther. 2007 Jan;14(1):82-90. Epub 2006 Sep 29.
Title: Potent antitumor efficacy of XAF1 delivered by conditionally replicative adenovirus vector via caspase-independent apoptosis.
Author: Qi, R|Gu, J|Zhang, Z|Yang, K|Li, B|Fan, J|Wang, C|He, Z|Qiao, L|Lin, Z|Liu, X Y
PMID: 17008933
Journal: Cancer. 2007 May 15;109(10):1996-2003.
Title: XAF1 mediates apoptosis through an extracellular signal-regulated kinase pathway in colon cancer.
Author: Yu, Li Fen|Wang, Jide|Zou, Bing|Lin, Marie C M|Wu, Yun Lin|Xia, Harry H X|Sun, Yun Wei|Gu, Qing|He, Hua|Lam, S K|Kung, Hsiang Fu|Wong, Benjamin C Y
PMID: 17385215
Journal: Apoptosis. 2007 Aug;12(8):1465-78.
Title: Expression of anti-apoptotic factors modulates Apo2L/TRAIL resistance in colon carcinoma cells.
Author: Lippa, Mara S|Strockbine, Laura D|Le, Tiep T|Branstetter, Daniel G|Strathdee, Craig A|Holland, Pamela M
PMID: 17440816
Journal: J Biol Chem. 2007 Jul 6;282(27):19273-81.
Title: Survivin down-regulation plays a crucial role in 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor-induced apoptosis in cancer.
Author: Kaneko, Reiko|Tsuji, Naoki|Asanuma, Koichi|Tanabe, Hiromi|Kobayashi, Daisuke|Watanabe, Naoki
PMID: 17472962
Journal: Mol Pharmacol. 2007 Sep;72(3):704-14. Epub 2007 Jun 19.
Title: Low-dose BBR3610 toxicity in colon cancer cells is p53-independent and enhanced by inhibition of epidermal growth factor receptor (ERBB1)-phosphatidyl inositol 3 kinase signaling.
Author: Mitchell, Clint|Kabolizadeh, Peyman|Ryan, John|Roberts, John D|Yacoub, Adly|Curiel, David T|Fisher, Paul B|Hagan, Michael P|Farrell, Nicholas P|Grant, Steven|Dent, Paul
PMID: 17578896
Journal: J Surg Res. 2007 Sep;142(1):184-94. Epub 2007 Jul 2.
Title: Modification of gene products involved in resistance to apoptosis in metastatic colon cancer cells: roles of Fas, Apaf-1, NFkappaB, IAPs, Smac/DIABLO, and AIF.
Author: Huerta, Sergio|Heinzerling, John H|Anguiano-Hernandez, Yu-Mei|Huerta-Yepez, Sara|Lin, Jeffrey|Chen, David|Bonavida, Benjamin|Livingston, Edward H
PMID: 17603079
Journal: Cancer Sci. 2007 Sep;98(9):1417-23.
Title: Lipoxygenase inhibitors induce death receptor 5/TRAIL-R2 expression and sensitize malignant tumor cells to TRAIL-induced apoptosis.
Author: Yoshida, Tatsushi|Shiraishi, Takumi|Horinaka, Mano|Nakata, Susumu|Yasuda, Takashi|Goda, Ahmed E|Wakada, Miki|Mizutani, Yoichi|Miki, Tsuneharu|Nishikawa, Akiyoshi|Sakai, Toshiyuki
PMID: 17645780
Journal: J Pharmacol Sci. 2007 Aug;104(4):374-83.
Title: Inhibition of cell growth and induction of apoptosis via inactivation of NF-kappaB by a sulfurcompound isolated from garlic in human colon cancer cells.
Author: Ban, Jung Ok|Yuk, Dong Yeon|Woo, Koan Sik|Kim, Tae Myoung|Lee, Ung Soo|Jeong, Heon-Sang|Kim, Dae Joong|Chung, Yeun Bok|Hwang, Bang Yeon|Oh, Ki Wan|Hong, Jin Tae
PMID: 17721042
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2007 Sep;27(9):1447-50.
Title: [Expression of HSF1 and XAF1 in gastro-intestinal cancer].
Author: Li, Ting|Chen, Cun-long|Wang, Ji-de|Cui, Sheng-da|Cui, Dan-yu|Guo, Wen
PMID: 17884799
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2007 Nov;27(11):1746-8.
Title: [Expression of X-linked inhibitor of apoptosis protein in colorectal cancer tissues].
Author: Li, Bin|Zhang, Yang-de|Tian, Bu-ning
PMID: 18024305
Journal: Oncogene. 2008 Jan 31;27(6):763-74. Epub 2007 Jul 23.
Title: MnSOD protects colorectal cancer cells from TRAIL-induced apoptosis by inhibition of Smac/DIABLO release.
Author: Mohr, A|Buneker, C|Gough, R P|Zwacka, R M
PMID: 17653087
Journal: Cancer Lett. 2008 Feb 18;260(1-2):62-71. Epub 2007 Nov 26.
Title: Regulation of XAF1 expression in human colon cancer cell by interferon beta: activation by the transcription regulator STAT1.
Author: Sun, Yunwei|Qiao, Liang|Xia, Harry Hua-Xiang|Lin, Marie C M|Zou, Bing|Yuan, Yaozong|Zhu, Senlin|Gu, Qing|Cheung, Ting Kin|Kung, Hsiang Fu|Yuen, Man Fung|Chan, Annie Oo|Wong, Benjamin C Y
PMID: 18035482
Journal: J Pathol. 2008 Feb;214(3):320-7.
Title: BRAF provides proliferation and survival signals in MSI colorectal carcinoma cells displaying BRAF(V600E) but not KRAS mutations.
Author: Preto, A|Figueiredo, J|Velho, S|Ribeiro, A S|Soares, P|Oliveira, C|Seruca, R
PMID: 18098337
Journal: Sci China C Life Sci. 2008 Jan;51(1):66-71.
Title: Ceramide induces release of mitochondrial proapoptotic proteins in caspase-dependent and -independent manner in HT-29 cells.
Author: Zhang, XiaoFeng|Li, BaiXiang|Zhang, Yang|Liu, JiaRen
PMID: 18176793
Journal: Eur J Pharmacol. 2008 Mar 17;582(1-3):17-25.
Title: Growth inhibitory effects of obovatol through induction of apoptotic cell death in prostate and colon cancer by blocking of NF-kappaB.
Author: Lee, So Yong|Yuk, Dong Yeon|Song, Ho Seub|Yoon, Do Young|Jung, Jae Kyung|Moon, Dong Cheul|Lee, Byung Seok|Hong, Jin Tae
PMID: 18241858
Journal: Int J Cancer. 2008 Jun 15;122(12):2858-63.
Title: Loss of XIAP sensitizes rosiglitazone-induced growth inhibition of colon cancer in vivo.
Author: Dai, Yun|Qiao, Liang|Chan, Kwok Wah|Zou, Bing|Ma, Juan|Lan, Hui Y|Gu, Qing|Li, Zesong|Wang, Yan|Wong, Benny L W|Wong, Benjamin C Y
PMID: 18351648
Journal: Digestion. 2008;77(2):79-86.
Title: Interactions between XIAP associated factor 1 and a nuclear co-activator, CBP, in colon cancer cells.
Author: Sun, Yunwei|Qiao, Liang|Zou, Bing|Xia, Harry Hua-Xiang|Gu, Qing|Ma, Juan|Lin, Marie C M|Zhu, Qi|Zhu, Senlin|Dai, Yun|Wong, Benjamin C Y
PMID: 18362468
Journal: Mol Ther. 2008 May;16(5):886-92.
Title: Therapeutic molecular targeting of 15-lipoxygenase-1 in colon cancer.
Author: Wu, Yuanqing|Fang, Bingliang|Yang, Xiulan Q|Wang, Li|Chen, Dongning|Krasnykh, Victor|Carter, Bing Z|Morris, Jeffrey S|Shureiqi, Imad
PMID: 18388920
Journal: Cancer Res. 2008 May 1;68(9):3379-88.
Title: Bortezomib (Velcade) induces p27Kip1 expression through S-phase kinase protein 2 degradation in colorectal cancer.
Author: Uddin, Shahab|Ahmed, Maqbool|Bavi, Prashant|El-Sayed, Raafat|Al-Sanea, Nasser|AbdulJabbar, Alaa|Ashari, Luai H|Alhomoud, Samar|Al-Dayel, Fouad|Hussain, Azhar R|Al-Kuraya, Khawla S
PMID: 18451165
Journal: Cancer Lett. 2008 Sep 18;268(2):260-71.
Title: Loss of XIAP sensitizes colon cancer cells to PPARgamma independent antitumor effects of troglitazone and 15-PGJ2.
Author: Qiao, Liang|Dai, Yun|Gu, Qing|Chan, Kwok Wah|Ma, Juan|Lan, H Y|Zou, Bing|Rocken, Christoph|Ebert, Matthias P A|Wong, Benjamin C Y
PMID: 18477501
Journal: Biochem Biophys Res Commun. 2008 Jul 18;372(1):236-42.
Title: Morusin induces apoptosis and suppresses NF-kappaB activity in human colorectal cancer HT-29 cells.
Author: Lee, Jenq-Chang|Won, Shen-Jeu|Chao, Chien-Lin|Wu, Feng-Ling|Liu, Hsiao-Sheng|Ling, Pin|Lin, Chun-Nan|Su, Chun-Li
PMID: 18485277
Journal: Carcinogenesis. 2008 Jul;29(7):1407-14.
Title: PPARgamma is involved in mesalazine-mediated induction of apoptosis and inhibition of cell growth in colon cancer cells.
Author: Schwab, Markus|Reynders, Veerle|Loitsch, Stefan|Shastri, Yogesh M|Steinhilber, Dieter|Schroder, Oliver|Stein, Jurgen
PMID: 18544567
Journal: Oncogene. 2008 Oct 9;27(46):6012-22.
Title: A mitochondrial block and expression of XIAP lead to resistance to TRAIL-induced apoptosis during progression to metastasis of a colon carcinoma.
Author: Ndozangue-Touriguine, O|Sebbagh, M|Merino, D|Micheau, O|Bertoglio, J|Breard, J
PMID: 18560353
Journal: Biochim Biophys Acta. 2008 Oct;1783(10):1903-13.
Title: Intracellular signaling dynamics during apoptosis execution in the presence or absence of X-linked-inhibitor-of-apoptosis-protein.
Author: O'Connor, Carla L|Anguissola, Sergio|Huber, Heinrich J|Dussmann, Heiko|Prehn, Jochen H M|Rehm, Markus
PMID: 18590777
Journal: Mol Cancer Ther. 2008 Jul;7(7):2203-11.
Title: Down-regulation of X-linked inhibitor of apoptosis synergistically enhanced peroxisome proliferator-activated receptor gamma ligand-induced growth inhibition in colon cancer.
Author: Qiao, Liang|Dai, Yun|Gu, Qing|Chan, Kwok Wah|Zou, Bing|Ma, Juan|Wang, Jide|Lan, Hui Y|Wong, Benjamin C Y
PMID: 18645029
Journal: Mol Ther. 2008 May;16(5):886-892.
Title: Therapeutic Molecular Targetingof 15-Lipoxygenase-1 in Colon Cancer.
Author: Wu, Yuanqing|Fang, Bingliang|Yang, Xiulan Q|Wang, Li|Chen, Dongning|Krasnykh, Victor|Carter, Bing Z|Morris, Jeffrey S|Shureiqi, Imad
PMID: 28178489
Journal: Int J Colorectal Dis. 2009 Mar;24(3):245-60.
Title: Gene expression profile in colon cancer cells with respect to XIAP expression status.
Author: Qiao, Liang|Li, Gloria H Y|Dai, Yun|Wang, Jide|Li, Zesong|Zou, Bing|Gu, Qing|Ma, Juan|Pang, R|Lan, Hui Y|Wong, Benjamin C Y
PMID: 18704457
Journal: Cancer Lett. 2009 Jan 8;273(1):98-106.
Title: Combined treatment of Caco-2 cells with butyrate and mesalazine inhibits cell proliferation and reduces Survivin protein level.
Author: Schwab, Markus|Reynders, Veerle|Steinhilber, Dieter|Stein, Jurgen
PMID: 18774638
Journal: Oncogene. 2009 Jan 8;28(1):63-72.
Title: Combined inhibition of FLIP and XIAP induces Bax-independent apoptosis in type II colorectal cancer cells.
Author: Wilson, T R|McEwan, M|McLaughlin, K|Le Clorennec, C|Allen, W L|Fennell, D A|Johnston, P G|Longley, D B
PMID: 18820704
Journal: Apoptosis. 2009 Feb;14(2):203-17.
Title: Sodium butyrate sensitizes human colon adenocarcinoma COLO 205 cells to both intrinsic and TNF-alpha-dependent extrinsic apoptosis.
Author: Pajak, Beata|Gajkowska, Barbara|Orzechowski, Arkadiusz
PMID: 19130237
Journal: Drug Resist Updat. 2009 Jun;12(3):55-64.
Title: Targeting apoptosis as an approach for gastrointestinal cancer therapy.
Author: Qiao, Liang|Wong, Benjamin C Y
PMID: 19278896
Journal: Cancer Res. 2009 Jun 1;69(11):4776-83.
Title: Peroxisome proliferator-activated receptor-gamma contributes to the inhibitory effects of Embelin on colon carcinogenesis.
Author: Dai, Yun|Qiao, Liang|Chan, Kwok Wah|Yang, Mo|Ye, Jieyu|Ma, Juan|Zou, Bing|Gu, Qing|Wang, Jide|Pang, Roberta|Lan, H Y|Wong, Benjamin C Y
PMID: 19458067
Journal: Arch Pharm Res. 2009 May;32(5):755-65.
Title: Inhibition of NF-kappaB by ginsenoside Rg3 enhances the susceptibility of colon cancer cells to docetaxel.
Author: Kim, Sun Mi|Lee, So Yong|Yuk, Dong Yeon|Moon, Dong Cheul|Choi, Sang Sook|Kim, Youngsoo|Han, Sang Bae|Oh, Ki-Wan|Hong, Jin Tae
PMID: 19471891
Journal: Oncol Rep. 2009 Aug;22(2):295-303.
Title: Immunoexpression of inhibitors of apoptosis proteins and their antagonist SMAC/DIABLO in colorectal carcinoma: correlation with apoptotic index, cellular proliferation and prognosis.
Author: De Oliveira Lima, Flavio|De Oliveira Costa, Henrique|Barrezueta, Luis Fernando Mesias|Fujiyama Oshima, Celina Tizuko|Silva, Jose Antonio Jr|Gomes, Thiago Simao|Pinheiro, Nathanael Jr|Neto, Ricardo Artigiani|Franco, Marcello
PMID: 19578769
Journal: Cancer Prev Res (Phila). 2009 Aug;2(8):732-42.
Title: Regulation of colorectal cancer cell apoptosis by the n-3 polyunsaturated fatty acids Docosahexaenoic and Eicosapentaenoic.
Author: Giros, Anna|Grzybowski, Mike|Sohn, Vanessa R|Pons, Elisenda|Fernandez-Morales, Jessica|Xicola, Rosa M|Sethi, Puja|Grzybowski, Jessica|Goel, Ajay|Boland, C Richard|Gassull, Miquel A|Llor, Xavier
PMID: 19638488
Journal: Mol Cancer Ther. 2009 Sep;8(9):2762-70.
Title: Adenovirus-mediated down-regulation of X-linked inhibitor of apoptosis protein inhibits colon cancer.
Author: Dai, Yun|Qiao, Liang|Chan, Kwok Wah|Yang, Mo|Ye, Jieyu|Zhang, Rongxin|Ma, Juan|Zou, Bing|Lam, Colin S C|Wang, Jide|Pang, Roberta|Tan, Victoria P Y|Lan, H Y|Wong, Benjamin C Y
PMID: 19737940
Journal: J Surg Oncol. 2009 Dec 15;100(8):708-12.
Title: Expression of X-linked inhibitor of apoptosis protein in human colorectal cancer and its correlation with prognosis.
Author: Xiang, Guoan|Wen, Xiaomin|Wang, Hanning|Chen, Kaiyun|Liu, Hao
PMID: 19777490
Journal: Mol Cancer. 2009 Nov 12;8:100.
Title: A combination of indol-3-carbinol and genistein synergistically induces apoptosis in human colon cancer HT-29 cells by inhibiting Akt phosphorylation and progression of autophagy.
Author: Nakamura, Yoshitaka|Yogosawa, Shingo|Izutani, Yasuyuki|Watanabe, Hirotsuna|Otsuji, Eigo|Sakai, Tosiyuki
PMID: 19909554
Journal: Cancer Lett. 2010 Jan 1;287(1):98-108.
Title: Nutlin-3 enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through up-regulation of death receptor 5 (DR5) in human sarcoma HOS cells and human colon cancer HCT116 cells.
Author: Hori, Takeshi|Kondo, Takashi|Kanamori, Masahiko|Tabuchi, Yoshiaki|Ogawa, Ryohei|Zhao, Qing-Li|Ahmed, Kanwal|Yasuda, Taketoshi|Seki, Shoji|Suzuki, Kayo|Kimura, Tomoatsu
PMID: 19577358
Journal: Mol Carcinog. 2010 Apr;49(4):324-36.
Title: Lysosomal destabilization and cathepsin B contributes for cytochrome c release and caspase activation in embelin-induced apoptosis.
Author: Joy, Beena|Sivadasan, Rajeeve|Abraham T, Emilia|John, Mohan|Sobhan, Praveen K|Seervi, Mahendra|T R, Santhoshkumar
PMID: 19943316
Journal: Cancer. 2010 Mar 1;116(5):1252-63.
Title: Tumor suppressor XIAP-Associated factor 1 (XAF1) cooperates with tumor necrosis factor-related apoptosis-inducing ligand to suppress colon cancer growth and trigger tumor regression.
Author: Tu, Shui Ping|Sun, Yun Wei|Cui, Jian Tao|Zou, Bing|Lin, Marie C M|Gu, Qing|Jiang, Shi Hu|Kung, Hsiang Fu|Korneluk, Robert G|Wong, Benjamin C Y
PMID: 20082449
Journal: Cancer Lett. 2010 Jul 28;293(2):158-66.
Title: Synergistic antitumor effect of TRAIL in combination with sunitinib in vitro and in vivo.
Author: Ding, Wanjing|Cai, Tianyu|Zhu, Hong|Wu, Rui|Tu, Chongxing|Yang, Liuqing|Lu, Wei|He, Qiaojun|Yang, Bo
PMID: 20137855
Journal: Mol Cancer Ther. 2010 Apr;9(4):833-43.
Title: beta-Ionone enhances TRAIL-induced apoptosis in hepatocellular carcinoma cells through Sp1-dependent upregulation of DR5 and downregulation of NF-kappaB activity.
Author: Kim, Mun-Ock|Moon, Dong-Oh|Kang, Chang-Hee|Kwon, Taeg Kyu|Choi, Yung Hyun|Kim, Gi-Young
PMID: 20354117
Journal: Clin Cancer Res. 2010 Apr 15;16(8):2320-32.
Title: Histone deacetylase inhibitors and 15-deoxy-Delta12,14-prostaglandin J2 synergistically induce apoptosis.
Author: Koyama, Makoto|Izutani, Yasuyuki|Goda, Ahmed E|Matsui, Taka-aki|Horinaka, Mano|Tomosugi, Mitsuhiro|Fujiwara, Jun|Nakamura, Yoshitaka|Wakada, Miki|Yogosawa, Shingo|Sowa, Yoshihiro|Sakai, Toshiyuki
PMID: 20371690
Journal: J Cell Physiol. 2010 Oct;225(1):266-75.
Title: Dauricine induces apoptosis, inhibits proliferation and invasion through inhibiting NF-kappaB signaling pathway in colon cancer cells.
Author: Yang, Zhengfeng|Li, Chenghai|Wang, Xiu|Zhai, Chunyan|Yi, Zhengfang|Wang, Lei|Liu, Bisheng|Du, Bing|Wu, Huihui|Guo, Xizhi|Liu, Mingyao|Li, Dali|Luo, Jian
PMID: 20509140
Journal: Surgery. 2010 Aug;148(2):346-53.
Title: In vitro and in vivo radiosensitization of colorectal cancer HT-29 cells by the smac mimetic JP-1201.
Author: Huerta, Sergio|Gao, Xiaohuan|Livingston, Edward H|Kapur, Payal|Sun, Haizhou|Anthony, Thomas
PMID: 20633731
Journal: J Biol Chem. 2010 Nov 12;285(46):35418-27.
Title: Gossypol induces death receptor-5 through activation of the ROS-ERK-CHOP pathway and sensitizes colon cancer cells to TRAIL.
Author: Sung, Bokyung|Ravindran, Jayaraj|Prasad, Sahdeo|Pandey, Manoj K|Aggarwal, Bharat B
PMID: 20837473
Journal: Oncol Rep. 2010 Dec;24(6):1509-14.
Title: Effects of the HDAC inhibitor CG2 in combination with irinotecan, 5-fluorouracil, or oxaliplatin on HCT116 colon cancer cells and xenografts.
Author: Na, Young-Soon|Kim, Seung-Mi|Jung, Kyung-Ah|Yang, Soo-Jin|Hong, Yong Sang|Ryu, Min-Hee|Ro, Seonggu|Cho, Dong-Hyung|Kim, Jin Cheon|Jin, Dong-Hoon|Lee, Jung Shin|Kim, Tae Won
PMID: 21042746
Journal: Cell Death Dis. 2010 Jun 3;1:e49.
Title: XIAP impairs Smac release from the mitochondria during apoptosis.
Author: Flanagan, L|Sebastia, J|Tuffy, L P|Spring, A|Lichawska, A|Devocelle, M|Prehn, J H M|Rehm, M
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Journal: Apoptosis. 2011 Feb;16(2):184-97.
Title: Sequential caspase-2 and caspase-8 activation is essential for saikosaponin a-induced apoptosis of human colon carcinoma cell lines.
Author: Kim, Byeong Mo|Hong, Sung Hee
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Title: Dimerization of Smac is crucial for its mitochondrial retention by XIAP subsequent to mitochondrial outer membrane permeabilization.
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Journal: Mol Cancer Ther. 2011 May;10(5):902-14.
Title: Therapeutic potential and molecular mechanism of a novel, potent, nonpeptide, Smac mimetic SM-164 in combination with TRAIL for cancer treatment.
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Journal: Br J Pharmacol. 2011 Nov;164(5):1433-44.
Title: Methyl jasmonate down-regulates survivin expression and sensitizes colon carcinoma cells towards TRAIL-induced cytotoxicity.
Author: Raviv, Z|Zilberberg, A|Cohen, S|Reischer-Pelech, D|Horrix, C|Berger, M R|Rosin-Arbesfeld, R|Flescher, E
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Journal: Biomed Pharmacother. 2011 Jun;65(3):175-82.
Title: Concomitant activation of caspase-9 and down-regulation of IAP proteins as a mechanism of apoptotic death in HepG2, T47D and HCT-116 cells upon exposure to a derivative from 4-aryl-4H-chromenes family.
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Journal: PLoS One. 2011;6(5):e20276.
Title: Calbindin 2 (CALB2) regulates 5-fluorouracil sensitivity in colorectal cancer by modulating the intrinsic apoptotic pathway.
Author: Stevenson, Leanne|Allen, Wendy L|Proutski, Irina|Stewart, Gail|Johnston, Louise|McCloskey, Karen|Wilson, Peter M|Longley, Daniel B|Johnston, Patrick G
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Title: The orphan nuclear receptor EAR2 is overexpressed in colorectal cancer and it regulates survivability of colon cancer cells.
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Journal: West Indian Med J. 2011 Mar;60(2):107-13.
Title: The effect of combining interferon-alpha and gefitinib in human colon cancer cell lines.
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Title: Induction of apoptosis in the SW620 colon carcinoma cell line by triterpene-enriched extracts from Ganoderma lucidum through activation of caspase-3.
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Journal: Dig Dis Sci. 2012 Feb;57(2):371-80.
Title: Knockdown of RON inhibits AP-1 activity and induces apoptosis and cell cycle arrest through the modulation of Akt/FoxO signaling in human colorectal cancer cells.
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Title: Clinical application of a systems model of apoptosis execution for the prediction of colorectal cancer therapy responses and personalisation of therapy.
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Journal: Br J Cancer. 2012 Apr 24;106(9):1499-1505.
Title: Apoptosome-dependent caspase activation proteins as prognostic markers in Stage II and III colorectal cancer.
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Journal: Nutr Cancer. 2012;64(4):617-26.
Title: Ursodeoxycholic acid protects colon cancer HCT116 cells from deoxycholic acid-induced apoptosis by inhibiting apoptosome formation.
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Journal: Apoptosis. 2012 Aug;17(8):797-809.
Title: The flavonolignan silibinin potentiates TRAIL-induced apoptosis in human colon adenocarcinoma and in derived TRAIL-resistant metastatic cells.
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Journal: BMC Cancer. 2012 Jun 6;12:221.
Title: Transforming growth factor-beta suppresses metastasis in a subset of human colon carcinoma cells.
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Title: Systems analysis of cancer cell heterogeneity in caspase-dependent apoptosis subsequent to mitochondrial outer membrane permeabilization.
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Journal: Oncol Rep. 2013 Feb;29(2):474-80.
Title: Casticin, a flavonoid, potentiates TRAIL-induced apoptosis through modulation of anti-apoptotic proteins and death receptor 5 in colon cancer cells.
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Journal: Cell Physiol Biochem. 2013;31(1):113-22.
Title: External Qi of Yan Xin Qigong inhibits activation of Akt, Erk1/2 and NF-kB and induces cell cycle arrest and apoptosis in colorectal cancer cells.
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Journal: PLoS One. 2013;8(2):e55710.
Title: The detergent-soluble cytoplasmic pool of survivin suppresses anoikis and its expression is associated with metastatic disease of human colon cancer.
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Journal: Cell Death Dis. 2013 Feb 21;4:e503.
Title: Delivery of sTRAIL variants by MSCs in combination with cytotoxic drug treatment leads to p53-independent enhanced antitumor effects.
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Journal: Oncol Rep. 2013 May;29(5):1851-8.
Title: Synergistic anticancer effects of curcumin and resveratrol in Hepa1-6 hepatocellular carcinoma cells.
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Title: Sanguinarine induces apoptosis in human colorectal cancer HCT-116 cells through ROS-mediated Egr-1 activation and mitochondrial dysfunction.
Author: Han, Min Ho|Kim, Gi-Young|Yoo, Young Hyun|Choi, Yung Hyun
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Journal: World J Surg Oncol. 2013 May 30;11:120.
Title: Hydroxycamptothecin induces apoptosis and inhibits tumor growth in colon cancer by the downregulation of survivin and XIAP expression.
Author: Fei, Bojian|Chi, Alfred L|Weng, Yuan
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Journal: Free Radic Biol Med. 2013 Oct;63:280-90.
Title: Aldose reductase inhibition enhances TRAIL-induced human colon cancer cell apoptosis through AKT/FOXO3a-dependent upregulation of death receptors.
Author: Shoeb, Mohammad|Ramana, Kota V|Srivastava, Satish K
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Journal: BMC Complement Altern Med. 2013 Jun 8;13:128.
Title: Teng-Long-Bu-Zhong-Tang, a Chinese herbal formula, enhances anticancer effects of 5--Fluorouracil in CT26 colon carcinoma.
Author: Deng, Shan|Hu, Bing|An, Hong-Mei|Du, Qin|Xu, Ling|Shen, Ke-Ping|Shi, Xiu-Feng|Wei, Meng-Meng|Wu, Yang
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Title: Double targeting of Survivin and XIAP radiosensitizes 3D grown human colorectal tumor cells and decreases migration.
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Journal: Oncotarget. 2013 Aug;4(8):1185-98.
Title: Combining trail with PI3 kinase or HSP90 inhibitors enhances apoptosis in colorectal cancer cells via suppression of survival signaling.
Author: Saturno, Grazia|Valenti, Melanie|De Haven Brandon, Alexis|Thomas, George V|Eccles, Suzanne|Clarke, Paul A|Workman, Paul
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Journal: Mol Cells. 2013 Sep;36(3):219-26.
Title: Midazolam induces cellular apoptosis in human cancer cells and inhibits tumor growth in xenograft mice.
Author: Mishra, Siddhartha Kumar|Kang, Ju-Hee|Lee, Chang Woo|Oh, Seung Hyun|Ryu, Jun Sun|Bae, Yun Soo|Kim, Hwan Mook
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Journal: J Mol Signal. 2013 Oct 1;8(1):10.
Title: Differential PKA activation and AKAP association determines cell fate in cancer cells.
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Journal: BMC Cancer. 2013 Nov 4;13:521.
Title: The association of TP53 mutations with the resistance of colorectal carcinoma to the insulin-like growth factor-1 receptor inhibitor picropodophyllin.
Author: Wang, Quan|Wei, Feng|Lv, Guoyue|Li, Chunsheng|Liu, Tongjun|Hadjipanayis, Costas G|Zhang, Guikai|Hao, Chunhai|Bellail, Anita C
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Journal: Pathol Oncol Res. 2014 Apr;20(2):301-7.
Title: Down-regulation of BAX gene during carcinogenesis and acquisition of resistance to 5-FU in colorectal cancer.
Author: Manoochehri, Mehdi|Karbasi, Ashraf|Bandehpour, Mojgan|Kazemi, Bahram
PMID: 24122668
Journal: Oncol Rep. 2014 Jan;31(1):87-94.
Title: In vivo analysis of insulin-like growth factor type 1 receptor humanized monoclonal antibody MK-0646 and small molecule kinase inhibitor OSI-906 in colorectal cancer.
Author: Leiphrakpam, Premila D|Agarwal, Ekta|Mathiesen, Michelle|Haferbier, Katie L|Brattain, Michael G|Chowdhury, Sanjib
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Journal: J Ethnopharmacol. 2014;151(1):292-8.
Title: Total alkaloids of Tripterygium hypoglaucum (levl.) Hutch inhibits tumor growth both in vitro and in vivo.
Author: Jiang, Xiao|Huang, Xiao-chun|Ao, Lin|Liu, Wen-bin|Han, Fei|Cao, Jia|Zhang, Dong-yun|Huang, Chuan-shu|Liu, Jin-Yi
PMID: 24212079
Journal: J Surg Oncol. 2014 Mar;109(3):255-65.
Title: Expression of apoptosis regulating proteins identifies stage II and III colon cancer patients with high risk of recurrence.
Author: Belt, Eric J Th|Stockmann, Hein B A C|Delis-van Diemen, Pien M|Bril, Herman|Tijssen, Marianne|van Essen, Hendrik F|Heymans, Martijn W|Belien, Jeroen A M|Carvalho, Beatriz|Cillessen, Saskia A G M|Meijer, Gerrit A
PMID: 24249458
Journal: BMC Cancer. 2014 Jan 15;14:24.
Title: Ceramide targets xIAP and cIAP1 to sensitize metastatic colon and breast cancer cells to apoptosis induction to suppress tumor progression.
Author: Paschall, Amy V|Zimmerman, Mary A|Torres, Christina M|Yang, Dafeng|Chen, May R|Li, Xia|Bieberich, Erhard|Bai, Aiping|Bielawski, Jacek|Bielawska, Alicja|Liu, Kebin
PMID: 24422988
Journal: Cell Signal. 2014 May;26(5):868-79.
Title: Ezrin expression and cell survival regulation in colorectal cancer.
Author: Leiphrakpam, Premila D|Rajput, Ashwani|Mathiesen, Michelle|Agarwal, Ekta|Lazenby, Audrey J|Are, Chandrakanth|Brattain, Michael G|Chowdhury, Sanjib
PMID: 24462708
Journal: BMC Cancer. 2014 Mar 1;14:145.
Title: Akt inhibitor MK-2206 promotes anti-tumor activity and cell death by modulation of AIF and Ezrin in colorectal cancer.
Author: Agarwal, Ekta|Chaudhuri, Anathbandhu|Leiphrakpam, Premila D|Haferbier, Katie L|Brattain, Michael G|Chowdhury, Sanjib
PMID: 24581231
Journal: Mol Cancer Ther. 2014 May;13(5):1206-16.
Title: Embelin reduces colitis-associated tumorigenesis through limiting IL-6/STAT3 signaling.
Author: Dai, Yun|Jiao, Hongmei|Teng, Guigen|Wang, Weihong|Zhang, Rongxin|Wang, Yunhong|Hebbard, Lionel|George, Jacob|Qiao, Liang
PMID: 24651526
Journal: J Agric Food Chem. 2014 May 21;62(20):4632-42.
Title: Cysteine-conjugated metabolites of ginger components, shogaols, induce apoptosis through oxidative stress-mediated p53 pathway in human colon cancer cells.
Author: Fu, Junsheng|Chen, Huadong|Soroka, Dominique N|Warin, Renaud F|Sang, Shengmin
PMID: 24786146
Journal: Mar Drugs. 2014 May 22;12(5):3072-90.
Title: Cracking the cytotoxicity code: apoptotic induction of 10-acetylirciformonin B is mediated through ROS generation and mitochondrial dysfunction.
Author: Shih, Huei-Chuan|El-Shazly, Mohamed|Juan, Yung-Shun|Chang, Chao-Yuan|Su, Jui-Hsin|Chen, Yu-Cheng|Shih, Shou-Ping|Chen, Huei-Mei|Wu, Yang-Chang|Lu, Mei-Chin
PMID: 24857964
Journal: Biochim Biophys Acta. 2014 Sep;1841(9):1308-17.
Title: DHA-mediated enhancement of TRAIL-induced apoptosis in colon cancer cells is associated with engagement of mitochondria and specific alterations in sphingolipid metabolism.
Author: Skender, Belma|Hofmanova, Jirina|Slavik, Josef|Jelinkova, Iva|Machala, Miroslav|Moyer, Mary Pat|Kozubik, Alois|Hyrslova Vaculova, Alena
PMID: 24953781
Journal: J Nat Prod. 2014 Aug 22;77(8):1825-30.
Title: 6-Acetonyldihydrochelerythrine Is a Potent Inducer of Apoptosis in HCT116 and SW620 Colon Cancer Cells.
Author: Mansoor, Tayyab A|Borralho, Pedro M|Luo, Xuan|Mulhovo, Silva|Rodrigues, Cecilia M P|Ferreira, Maria-Jose U
PMID: 25066282
Journal: Cancer Lett. 2014 Dec 1;355(1):141-7.
Title: Aldose reductase inhibition suppresses azoxymethane-induced colonic premalignant lesions in C57BL/KsJ-db/db mice.
Author: Saxena, Ashish|Shoeb, Mohammad|Tammali, Ravinder|Ramana, Kota V|Srivastava, Satish K
PMID: 25218594
Journal: Theranostics. 2014 Sep 19;4(12):1193-208.
Title: MiR-194 deregulation contributes to colorectal carcinogenesis via targeting AKT2 pathway.
Author: Zhao, Hui-Jun|Ren, Lin-Lin|Wang, Zhen-Hua|Sun, Tian-Tian|Yu, Ya-Nan|Wang, Ying-Chao|Yan, Ting-Ting|Zou, Weiping|He, Jie|Zhang, Yaou|Hong, Jie|Fang, Jing-Yuan
PMID: 25285168
Journal: World J Gastroenterol. 2014 Nov 7;20(41):15275-88.
Title: Differential control of growth, apoptotic activity and gene expression in human colon cancer cells by extracts derived from medicinal herbs, Rhazya stricta and Zingiber officinale and their combination.
Author: Elkady, Ayman I|Hussein, Rania Abd El Hamid|Abu-Zinadah, Osama A
PMID: 25386076
Journal: Cell Death Dis. 2014 Dec 11;5:e1570.
Title: XIAP-targeting drugs re-sensitize PIK3CA-mutated colorectal cancer cells for death receptor-induced apoptosis.
Author: Ehrenschwender, M|Bittner, S|Seibold, K|Wajant, H
PMID: 25501831
Journal: Int J Clin Oncol. 2015 Feb;20(1):117-25.
Title: Usefulness of alternate-day administration of S-1 and leucovorin in a xenograft mouse model of colorectal cancer: a shorter drug-free interval leads to more efficient antitumor effects.
Author: Komura, Toshihiro|Miura, Koh|Shirasaka, Tetsuhiko|Ohnuma, Shinobu|Shimada, Miki|Kajiwara, Taiki|Fujishima, Fumiyoshi|Philchenkov, Alex|Nakagawa, Kei|Kudoh, Katsuyoshi|Haneda, Sho|Toshima, Masahide|Kohyama, Atsushi|Musha, Hiroaki|Naitoh, Takeshi|Shibata, C
PMID: 24802097
Journal: Oncogene. 2015 May 21;34(21):2753-63.
Title: The Gbeta5 protein regulates sensitivity to TRAIL-induced cell death in colon carcinoma.
Author: Fuchs, D|Metzig, M|Bickeboller, M|Brandel, C|Roth, W
PMID: 25043307
Journal: Food Chem Toxicol. 2015 Jan;75:14-23.
Title: Chemopreventive effects of standardized ethanol extract from the aerial parts of Artemisia princeps Pampanini cv. Sajabal via NF-kappaB inactivation on colitis-associated colon tumorigenesis in mice.
Author: Chung, Kyung-Sook|Choi, Hye-Eun|Shin, Ji-Sun|Cho, Eu-Jin|Cho, Young-Wuk|Choi, Jung-Hye|Baek, Nam-In|Lee, Kyung-Tae
PMID: 25449198
Journal: Arch Pharm Res. 2015 Feb;38(2):239-48.
Title: Indirect modulation of sensitivity to 5-fluorouracil by microRNA-96 in human colorectal cancer cells.
Author: Kim, Sun-Ah|Kim, Injung|Yoon, Sungjoo Kim|Lee, Eun Kyung|Kuh, Hyo-Jeong
PMID: 25502560
Journal: J Nanobiotechnology. 2015 Mar 3;13:18.
Title: Biocompatible iota-carrageenan-gamma-maghemite nanocomposite for biomedical applications - synthesis, characterization and in vitro anticancer efficacy.
Author: Raman, Maya|Devi, Viswambari|Doble, Mukesh
PMID: 25890231
Journal: Tumour Biol. 2015 Sep;36(10):8107-20.
Title: Cellular prion protein contributes to LS 174T colon cancer cell carcinogenesis by increasing invasiveness and resistance against doxorubicin-induced apoptosis.
Author: Chieng, Cornelius Kwang-Lee|Say, Yee-How
PMID: 25983001
Journal: Radiat Oncol. 2015 Jun 13;10:131.
Title: High levels of X-linked Inhibitor-of-Apoptosis Protein (XIAP) are indicative of radio chemotherapy resistance in rectal cancer.
Author: Flanagan, L|Kehoe, J|Fay, J|Bacon, O|Lindner, A U|Kay, E W|Deasy, J|McNamara, D A|Prehn, J H M
PMID: 26071313
Journal: Oncotarget. 2015 Sep 22;6(28):25339-55.
Title: CRNDE affects the malignant biological characteristics of human glioma stem cells by negatively regulating miR-186.
Author: Zheng, Jian|Li, Xiao-dong|Wang, Ping|Liu, Xiao-bai|Xue, Yi-xue|Hu, Yi|Li, Zhen|Li, Zhi-qing|Wang, Zhen-hua|Liu, Yun-hui
PMID: 26231038
Journal: Cell Death Dis. 2015 Aug 6;6:e1845.
Title: MicroRNA-587 antagonizes 5-FU-induced apoptosis and confers drug resistance by regulating PPP2R1B expression in colorectal cancer.
Author: Zhang, Yang|Talmon, G|Wang, J
PMID: 26247730
Journal: Biomaterials. 2015 Dec;71:84-99.
Title: LNA aptamer based multi-modal, Fe3O4-saturated lactoferrin (Fe3O4-bLf) nanocarriers for triple positive (EpCAM, CD133, CD44) colon tumor targeting and NIR, MRI and CT imaging.
Author: Roy, Kislay|Kanwar, Rupinder K|Kanwar, Jagat R
PMID: 26318819
Journal: Radiat Oncol. 2015 Sep 17;10:198.
Title: The SMAC mimetic BV6 sensitizes colorectal cancer cells to ionizing radiation by interfering with DNA repair processes and enhancing apoptosis.
Author: Hehlgans, Stephanie|Oppermann, Julius|Reichert, Sebastian|Fulda, Simone|Rodel, Claus|Rodel, Franz
PMID: 26383618
Journal: J Exp Clin Cancer Res. 2015 Nov 21;34:142.
Title: A-kinase anchor protein 4 (AKAP4) a promising therapeutic target of colorectal cancer.
Author: Jagadish, Nirmala|Parashar, Deepak|Gupta, Namita|Agarwal, Sumit|Purohit, Sapna|Kumar, Vikash|Sharma, Aditi|Fatima, Rukhsar|Topno, Amos Prashant|Shaha, Chandrima|Suri, Anil
PMID: 26590805
Journal: Environ Toxicol. 2016 Aug;31(8):957-69.
Title: Crude extract of Rheum palmatum L. Induces cell cycle arrest S phase and apoptosis through mitochondrial-dependent pathways in U-2 OS human osteosarcoma cells.
Author: Lin, Chin-Chung|Lee, Ming-Huei|Lin, Ju-Hwa|Lin, Meng-Liang|Chueh, Fu-Shin|Yu, Chien-Chih|Lin, Jing-Pin|Chou, Yu-Cheng|Hsu, Shu-Chun|Chung, Jing-Gung
PMID: 25689151
Journal: Oncotarget. 2016 Feb 9;7(6):7161-78.
Title: The probiotic Propionibacterium freudenreichii as a new adjuvant for TRAIL-based therapy in colorectal cancer.
Author: Cousin, Fabien J|Jouan-Lanhouet, Sandrine|Theret, Nathalie|Brenner, Catherine|Jouan, Elodie|Le Moigne-Muller, Gwenaelle|Dimanche-Boitrel, Marie-Therese|Jan, Gwenael
PMID: 26771233
Journal: PLoS One. 2016 Feb 9;11(2):e0148775.
Title: Flavokawain C Inhibits Cell Cycle and Promotes Apoptosis, Associated with Endoplasmic Reticulum Stress and Regulation of MAPKs and Akt Signaling Pathways in HCT 116 Human Colon Carcinoma Cells.
Author: Phang, Chung-Weng|Karsani, Saiful Anuar|Sethi, Gautam|Abd Malek, Sri Nurestri
PMID: 26859847
Journal: Virchows Arch. 2016 May;468(5):559-67.
Title: The X-linked inhibitor of apoptosis protein is an independent prognostic marker for rectal adenocarcinoma after preoperative chemoradiotherapy.
Author: Chen, Yi-Ting|Tsao, Shu-Chuan|Tsai, Hung-Pei|Wang, Jaw-Yuan|Chai, Chee-Yin
PMID: 26915033
Journal: Biochem Biophys Res Commun. 2016 Apr 29;473(2):586-92.
Title: Bakuchiol sensitizes cancer cells to TRAIL through ROS- and JNK-mediated upregulation of death receptors and downregulation of survival proteins.
Author: Park, Mi Hee|Kim, Jong Han|Chung, Young-Ho|Lee, Seung Ho
PMID: 27033605
Journal: Oncotarget. 2016 Jul 5;7(27):41488-41504.
Title: Hypoxia regulates TRAIL sensitivity of colorectal cancer cells through mitochondrial autophagy.
Author: Knoll, Gertrud|Bittner, Sebastian|Kurz, Maria|Jantsch, Jonathan|Ehrenschwender, Martin
PMID: 27166192
Journal: Oncol Rep. 2016 Jul;36(1):542-50.
Title: MicroRNA-874 inhibits growth, induces apoptosis and reverses chemoresistance in colorectal cancer by targeting X-linked inhibitor of apoptosis protein.
Author: Han, Jinfeng|Liu, Zhongmin|Wang, Nanya|Pan, Weiyun
PMID: 27221209
Journal: Toxicol Lett. 2016 Aug 22;257:84-96.
Title: Isoledene from Mesua ferrea oleo-gum resin induces apoptosis in HCT 116 cells through ROS-mediated modulation of multiple proteins in the apoptotic pathways: A mechanistic study.
Author: Asif, Muhammad|Shafaei, Armaghan|Jafari, Seyedeh Fatemeh|Mohamed, Shazmin Kithur|Ezzat, Mohammed Oday|Abdul Majid, Aman Shah|Oon, Chern Ein|Petersen, Sven H|Kono, Koji|Abdul Majid, Amin Malik Shah
PMID: 27268964
Journal: Anticancer Res. 2016 Jul;36(7):3383-94.
Title: Enhanced TLR4 Expression on Colon Cancer Cells After Chemotherapy Promotes Cell Survival and Epithelial-Mesenchymal Transition Through Phosphorylation of GSK3beta.
Author: Chung, Yoon Hee|Kim, Daejin
PMID: 27354597
Journal: Oncotarget. 2016 Oct 18;7(42):68546-68558.
Title: Specific inhibition of p110alpha subunit of PI3K: putative therapeutic strategy for KRAS mutant colorectal cancers.
Author: Fernandes, Maria Sofia|Melo, Soraia|Velho, Sergia|Carneiro, Patricia|Carneiro, Fatima|Seruca, Raquel
PMID: 27602501
Journal: J Ethnopharmacol. 2016 Dec 24;194:236-244.
Title: (3'R)-hydroxytabernaelegantine C: A bisindole alkaloid with potent apoptosis inducing activity in colon (HCT116, SW620) and liver (HepG2) cancer cells.
Author: Paterna, Angela|Gomes, Sofia E|Borralho, Pedro M|Mulhovo, Silva|Rodrigues, Cecilia M P|Ferreira, Maria-Jose U
PMID: 27616029
Journal: Food Funct. 2016 Dec 7;7(12):4823-4829.
Title: Evaluation of a furochromone from the halophyte Corydalis heterocarpa for cytotoxic activity against human gastric cancer (AGS) cells.
Author: Kong, Chang-Suk|Kim, You Ah|Kim, Hojun|Seo, Youngwan
PMID: 27808331
Journal: Sci Rep. 2016 Nov 9;6:36532.
Title: Death receptor 5 (DR5) and a 5-gene apoptotic biomarker panel with significant differential diagnostic potential in colorectal cancer.
Author: Devetzi, Marina|Kosmidou, Vivian|Vlassi, Margarita|Perysinakis, Iraklis|Aggeli, Chrysanthi|Choreftaki, Theodosia|Zografos, Georgios N|Pintzas, Alexander
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Journal: Mol Cancer Ther. 2016 Dec;15(12):3055-3063.
Title: STAT1 Promotes KRAS Colon Tumor Growth and Susceptibility to Pharmacological Inhibition of Translation Initiation Factor eIF4A.
Author: Wang, Shuo|Darini, Cedric|Desaubry, Laurent|Koromilas, Antonis E
PMID: 27913706
Journal: Oncotarget. 2017 Jan 31;8(5):7502-7520.
Title: BTG1 might be employed as a biomarker for carcinogenesis and a target for gene therapy in colorectal cancers.
Author: Zhao, Shuang|Chen, Shu-Rui|Yang, Xue-Feng|Shen, Dao-Fu|Takano, Yasuo|Su, Rong-Jian|Zheng, Hua-Chuan
PMID: 27447746
Journal: Gastroenterology. 2017 Mar;152(4):867-879.
Title: Inhibitor of Apoptosis Protein-1 Regulates Tumor Necrosis Factor-Mediated Destruction of Intestinal Epithelial Cells.
Author: Grabinger, Thomas|Bode, Konstantin J|Demgenski, Janine|Seitz, Carina|Delgado, M Eugenia|Kostadinova, Feodora|Reinhold, Cindy|Etemadi, Nima|Wilhelm, Sabine|Schweinlin, Matthias|Hanggi, Kay|Knop, Janin|Hauck, Christof|Walles, Heike|Silke, John|Wajant, Haral
PMID: 27889570
Journal: Cancer Sci. 2017 Mar;108(3):390-397.
Title: Downregulation of microRNA-100/microRNA-125b is associated with lymph node metastasis in early colorectal cancer with submucosal invasion.
Author: Fujino, Yasuteru|Takeishi, Shunsaku|Nishida, Kensei|Okamoto, Koichi|Muguruma, Naoki|Kimura, Tetsuo|Kitamura, Shinji|Miyamoto, Hiroshi|Fujimoto, Akiko|Higashijima, Jun|Shimada, Mitsuo|Rokutan, Kazuhito|Takayama, Tetsuji
PMID: 28032929
Journal: PLoS One. 2017 Mar 29;12(3):e0174591.
Title: Tetraarsenic hexoxide induces G2/M arrest, apoptosis, and autophagy via PI3K/Akt suppression and p38 MAPK activation in SW620 human colon cancer cells.
Author: Nagappan, Arulkumar|Lee, Won Sup|Yun, Jeong Won|Lu, Jing Nan|Chang, Seong-Hwan|Jeong, Jae-Hoon|Kim, Gon Sup|Jung, Jin-Myung|Hong, Soon Chan
PMID: 28355296
Journal: Oncotarget. 2017 Mar 14;8(11):18322-18336.
Title: The suppressing effects of BTG3 expression on aggressive behaviors and phenotypes of colorectal cancer: An in vitro and vivo study.
Author: Zheng, Hua-Chuan|He, Hao-Yu|Wu, Ji-Cheng|Li, Jing|Zhao, Shuang|Zhao, Gui-Feng|Jiang, Hua-Mao|Yu, Xue-Wen|Li, Zhi-Jie
PMID: 28407690
Journal: PLoS One. 2017 Apr 17;12(4):e0176096.
Title: TGFbeta/Smad3 regulates proliferation and apoptosis through IRS-1 inhibition in colon cancer cells.
Author: Bailey, Katie L|Agarwal, Ekta|Chowdhury, Sanjib|Luo, Jiangtao|Brattain, Michael G|Black, Jennifer D|Wang, Jing
PMID: 28414818
Journal: Proc Natl Acad Sci U S A. 2017 May 30;114(22):5683-5688.
Title: Identification of XAF1-MT2A mutual antagonism as a molecular switch in cell-fate decisions under stressful conditions.
Author: Shin, Cheol-Hee|Lee, Min-Goo|Han, Jikhyon|Jeong, Seong-In|Ryu, Byung-Kyu|Chi, Sung-Gil
PMID: 28507149
Journal: Sci Rep. 2017 Jun 23;7(1):4194.
Title: miR-15b-5p resensitizes colon cancer cells to 5-fluorouracil by promoting apoptosis via the NF-kappaB/XIAP axis.
Author: Zhao, Ci|Zhao, Qi|Zhang, Chunhui|Wang, Guangyu|Yao, Yuanfei|Huang, Xiaoyi|Zhan, Fei|Zhu, Yuanyuan|Shi, Jiaqi|Chen, Jianan|Yan, Feihu|Zhang, Yanqiao
PMID: 28646148
Journal: Integr Med Res. 2017 Jun;6(2):179-189.
Title: Induction of apoptosis by Dae-Hwang-Mok-Dan-Tang in HCT-116 colon cancer cells through activation of caspases and inactivation of the phosphatidylinositol 3-kinase/Akt signaling.
Author: Park, Cheol|Hong, Su Hyun|Choi, Yung Hyun
PMID: 28664141
Journal: Ann Clin Lab Sci. 2017 May;47(3):264-270.
Title: HtrA1 Down-regulation Induces Cisplatin Resistance in Colon Cancer by Increasing XIAP and Activating PI3K/Akt Pathway.
Author: Xiong, Zhenfang|Fu, Zhonghua|Shi, Jun|Jiang, Xiaozhen|Wan, Hongping
PMID: 28667026
Journal: J Cancer Prev. 2017 Jun;22(2):98-102.
Title: Evaluation of the Expression of the Inhibitor of Apoptosis Protein Family and Human Telomerase Reverse Transcriptase in Patients With Advanced Colorectal Adenoma.
Author: Choi, Joon Young|Yoon, Hyuk|Na, Gyeongjae|Choi, Yoon Jin|Shin, Cheol Min|Park, Young Soo|Kim, Nayoung|Lee, Dong Ho
PMID: 28698863
Journal: Int J Oncol. 2017 Sep;51(3):959-966.
Title: Malformin A1 treatment alters invasive and oncogenic phenotypes of human colorectal cancer cells through stimulation of the p38 signaling pathway.
Author: Park, Sun-Young|Oh, Hyung-Hoon|Park, Young-Lan|Yu, Hyung-Min|Myung, Dae-Seong|Cho, Sung-Bum|Lee, Wan-Sik|Park, Daeho|Joo, Young-Eun
PMID: 28713983
Journal: Sci Rep. 2017 Sep 8;7(1):10939.
Title: SATB2/beta-catenin/TCF-LEF pathway induces cellular transformation by generating cancer stem cells in colorectal cancer.
Author: Yu, Wei|Ma, Yiming|Shankar, Sharmila|Srivastava, Rakesh K
PMID: 28887549
Journal: Food Chem. 2018 Mar 1;242:378-388.
Title: Comparison of the effect of chemical composition of anthocyanin-rich plant extracts on colon cancer cell proliferation and their potential mechanism of action using in vitro, in silico, and biochemical assays.
Author: Mazewski, Candice|Liang, Katie|Gonzalez de Mejia, Elvira
PMID: 29037704
Journal: Int J Cancer. 2018 May 15;142(10):2040-2055.
Title: XIAP overexpression promotes bladder cancer invasion in vitro and lung metastasis in vivo via enhancing nucleolin-mediated Rho-GDIbeta mRNA stability.
Author: Yu, Yonghui|Jin, Honglei|Xu, Jiheng|Gu, Jiayan|Li, Xin|Xie, Qipeng|Huang, Haishan|Li, Jingxia|Tian, Zhongxian|Jiang, Guosong|Chen, Caiyi|He, Feng|Wu, Xue-Ru|Huang, Chuanshu
PMID: 29250796
Journal: Biochim Biophys Acta Mol Basis Dis. 2018 May;1864(5 Pt A):1539-1551.
Title: The G protein-coupled P2Y(6) receptor promotes colorectal cancer tumorigenesis by inhibiting apoptosis.
Author: Placet, Morgane|Arguin, Guillaume|Molle, Caroline M|Babeu, Jean-Philippe|Jones, Christine|Carrier, Julie C|Robaye, Bernand|Geha, Sameh|Boudreau, Francois|Gendron, Fernand-Pierre
PMID: 29454075
Journal: J Biol Chem. 2018 May 25;293(21):8242-8254.
Title: TGFbeta and IGF1R signaling activates protein kinase A through differential regulation of ezrin phosphorylation in colon cancer cells.
Author: Leiphrakpam, Premila D|Brattain, Michael G|Black, Jennifer D|Wang, Jing
PMID: 29599290
Journal: Acta Pharmacol Sin. 2018 May 17. pii: 10.1038/s41401-018-0005-y.
Title: Varacin-1, a novel analog of varacin C, induces p53-independent apoptosis in cancer cells through ROS-mediated reduction of XIAP.
Author: Zhou, Jing|Li, Wen-Li|Wang, Zi-Xuan|Chen, Nai-Yuan|Tang, Yue|Hu, Xiao-Xiao|Deng, Jing-Huan|Lu, Yixin|Lu, Guo-Dong
PMID: 29773887
Journal: Oncol Lett. 2018 May;15(5):8019-8026.
Title: Bufalin and 5-fluorouracil synergistically induce apoptosis in colorectal cancer cells.
Author: Dai, Xiao-Yu|Zhou, Bao-Feng|Xie, Yang-Yang|Lou, Jie|Li, Ke-Qiang
PMID: 29849804
Journal: Environ Toxicol Pharmacol. 2018 Sep;62:164-176.
Title: KT2 and RT2 modified antimicrobial peptides derived from Crocodylus siamensis Leucrocin I show activity against human colon cancer HCT-116 cells.
Author: Maijaroen, Surachai|Jangpromma, Nisachon|Daduang, Jureerut|Klaynongsruang, Sompong
PMID: 30031283
Journal: Phytomedicine. 2018 Sep 15;48:152-160.
Title: Coptisine-induced apoptosis in human colon cancer cells (HCT-116) is mediated by PI3K/Akt and mitochondrial-associated apoptotic pathway.
Author: Han, Bing|Jiang, Pu|Li, Zhaoxing|Yu, Yang|Huang, Tao|Ye, Xiaoli|Li, Xuegang
PMID: 30195873
Journal: Oncogene. 2018 Oct 1. pii: 10.1038/s41388-018-0513-8.
Title: XIAP facilitates breast and colon carcinoma growth via promotion of p62 depletion through ubiquitination-dependent proteasomal degradation.
Author: Huang, Xing|Wang, Xiao-Nan|Yuan, Xiao-Dong|Wu, Wen-Yong|Lobie, Peter E|Wu, Zhengsheng
PMID: 30275562