Primary Site >> Colorectal Cancer
Gene >> XIAP
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Ref: Augmentation of apoptosis and tumor regression by flavopiridol in the presence of CPT-11 in Hct116 colon cancer monolayers and xenografts. PMID: 11751522 |
Ref: Mechanisms involved in development of resistance to adenovirus-mediated proapoptotic gene therapy in DLD1 human colon cancer cell line. PMID: 12215894 Ref: Defining characteristics of Types I and II apoptotic cells in response to TRAIL. PMID: 12407450 |
Ref: Rottlerin sensitizes colon carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis via uncoupling of the mitochondria independent of protein kinase C. PMID: 12941843 Ref: Induction of cIAP-2 in human colon cancer cells through PKC delta/NF-kappa B. PMID: 14527959 Ref: Coexistence of high levels of apoptotic signaling and inhibitor of apoptosis proteins in human tumor cells: implication for cancer specific therapy. PMID: 14583479 |
Ref: Expression of IAP family proteins in colon cancers from patients with different age groups. PMID: 15138717 Ref: Sodium butyrate sensitizes TRAIL-mediated apoptosis by induction of transcription from the DR5 gene promoter through Sp1 sites in colon cancer cells. PMID: 15142888 Ref: Diffuse expression of hRFI is correlated with blood vessel invasion in gastric carcinoma. PMID: 15591455 Ref: Elimination of hepatic metastases of colon cancer cells via p53-independent cross-talk between irinotecan and Apo2 ligand/TRAIL. PMID: 15604280 Ref: Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis is inhibited by Bcl-2 but restored by the small molecule Bcl-2 inhibitor, HA 14-1, in human colon cancer cells. PMID: 15623604 Ref: Lessons from TRAIL-resistance mechanisms in colorectal cancer cells: paving the road to patient-tailored therapy. PMID: 15790545 |
Ref: Low expression of XIAP-associated factor 1 in human colorectal cancers. PMID: 15667552 Ref: Casein kinase II (CK2) enhances death-inducing signaling complex (DISC) activity in TRAIL-induced apoptosis in human colon carcinoma cell lines. PMID: 15688023 Ref: [Frequent epigenetic inactivation of XAF1 by promotor hypermethylation in human colon cancers]. PMID: 15843754 Ref: 17-Allylamino-17-demethoxygeldanamycin overcomes TRAIL resistance in colon cancer cell lines. PMID: 15993848 Ref: Molecular targets and anticancer potential of indole-3-carbinol and its derivatives. PMID: 16082211 Ref: X-Linked inhibitor of apoptosis protein expression level in colorectal cancer is regulated by hepatocyte growth factor/C-met pathway via Akt signaling. PMID: 16278380 |
Ref: Overexpression of p65/RelA potentiates curcumin-induced apoptosis in HCT116 human colon cancer cells. PMID: 16497702 Ref: Pioglitazone, a synthetic ligand for PPARgamma, induces apoptosis in RB-deficient human colorectal cancer cells. PMID: 16520894 Ref: All-trans retinoic acid induces XAF1 expression through an interferon regulatory factor-1 element in colon cancer. PMID: 16530516 Ref: PPARgamma is a key target of butyrate-induced caspase-3 activation in the colorectal cancer cell line Caco-2. PMID: 16927016 Ref: Proteasome inhibitors sensitize colon carcinoma cells to TRAIL-induced apoptosis via enhanced release of Smac/DIABLO from the mitochondria. PMID: 16998592 Ref: Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers. PMID: 17087954 |
Ref: Potent antitumor efficacy of XAF1 delivered by conditionally replicative adenovirus vector via caspase-independent apoptosis. PMID: 17008933 Ref: XAF1 mediates apoptosis through an extracellular signal-regulated kinase pathway in colon cancer. PMID: 17385215 Ref: Expression of anti-apoptotic factors modulates Apo2L/TRAIL resistance in colon carcinoma cells. PMID: 17440816 Ref: Survivin down-regulation plays a crucial role in 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor-induced apoptosis in cancer. PMID: 17472962 Ref: Low-dose BBR3610 toxicity in colon cancer cells is p53-independent and enhanced by inhibition of epidermal growth factor receptor (ERBB1)-phosphatidyl inositol 3 kinase signaling. PMID: 17578896 Ref: Modification of gene products involved in resistance to apoptosis in metastatic colon cancer cells: roles of Fas, Apaf-1, NFkappaB, IAPs, Smac/DIABLO, and AIF. PMID: 17603079 Ref: Lipoxygenase inhibitors induce death receptor 5/TRAIL-R2 expression and sensitize malignant tumor cells to TRAIL-induced apoptosis. PMID: 17645780 Ref: Inhibition of cell growth and induction of apoptosis via inactivation of NF-kappaB by a sulfurcompound isolated from garlic in human colon cancer cells. PMID: 17721042 Ref: [Expression of HSF1 and XAF1 in gastro-intestinal cancer]. PMID: 17884799 Ref: [Expression of X-linked inhibitor of apoptosis protein in colorectal cancer tissues]. PMID: 18024305 |
Ref: MnSOD protects colorectal cancer cells from TRAIL-induced apoptosis by inhibition of Smac/DIABLO release. PMID: 17653087 Ref: Regulation of XAF1 expression in human colon cancer cell by interferon beta: activation by the transcription regulator STAT1. PMID: 18035482 Ref: BRAF provides proliferation and survival signals in MSI colorectal carcinoma cells displaying BRAF(V600E) but not KRAS mutations. PMID: 18098337 Ref: Ceramide induces release of mitochondrial proapoptotic proteins in caspase-dependent and -independent manner in HT-29 cells. PMID: 18176793 Ref: Growth inhibitory effects of obovatol through induction of apoptotic cell death in prostate and colon cancer by blocking of NF-kappaB. PMID: 18241858 Ref: Loss of XIAP sensitizes rosiglitazone-induced growth inhibition of colon cancer in vivo. PMID: 18351648 Ref: Interactions between XIAP associated factor 1 and a nuclear co-activator, CBP, in colon cancer cells. PMID: 18362468 Ref: Therapeutic molecular targeting of 15-lipoxygenase-1 in colon cancer. PMID: 18388920 Ref: Bortezomib (Velcade) induces p27Kip1 expression through S-phase kinase protein 2 degradation in colorectal cancer. PMID: 18451165 Ref: Loss of XIAP sensitizes colon cancer cells to PPARgamma independent antitumor effects of troglitazone and 15-PGJ2. PMID: 18477501 Ref: Morusin induces apoptosis and suppresses NF-kappaB activity in human colorectal cancer HT-29 cells. PMID: 18485277 Ref: PPARgamma is involved in mesalazine-mediated induction of apoptosis and inhibition of cell growth in colon cancer cells. PMID: 18544567 Ref: A mitochondrial block and expression of XIAP lead to resistance to TRAIL-induced apoptosis during progression to metastasis of a colon carcinoma. PMID: 18560353 Ref: Intracellular signaling dynamics during apoptosis execution in the presence or absence of X-linked-inhibitor-of-apoptosis-protein. PMID: 18590777 Ref: Down-regulation of X-linked inhibitor of apoptosis synergistically enhanced peroxisome proliferator-activated receptor gamma ligand-induced growth inhibition in colon cancer. PMID: 18645029 Ref: Therapeutic Molecular Targetingof 15-Lipoxygenase-1 in Colon Cancer. PMID: 28178489 |
Ref: Gene expression profile in colon cancer cells with respect to XIAP expression status. PMID: 18704457 Ref: Combined treatment of Caco-2 cells with butyrate and mesalazine inhibits cell proliferation and reduces Survivin protein level. PMID: 18774638 Ref: Combined inhibition of FLIP and XIAP induces Bax-independent apoptosis in type II colorectal cancer cells. PMID: 18820704 Ref: Sodium butyrate sensitizes human colon adenocarcinoma COLO 205 cells to both intrinsic and TNF-alpha-dependent extrinsic apoptosis. PMID: 19130237 Ref: Targeting apoptosis as an approach for gastrointestinal cancer therapy. PMID: 19278896 Ref: Peroxisome proliferator-activated receptor-gamma contributes to the inhibitory effects of Embelin on colon carcinogenesis. PMID: 19458067 Ref: Inhibition of NF-kappaB by ginsenoside Rg3 enhances the susceptibility of colon cancer cells to docetaxel. PMID: 19471891 Ref: Immunoexpression of inhibitors of apoptosis proteins and their antagonist SMAC/DIABLO in colorectal carcinoma: correlation with apoptotic index, cellular proliferation and prognosis. PMID: 19578769 Ref: Regulation of colorectal cancer cell apoptosis by the n-3 polyunsaturated fatty acids Docosahexaenoic and Eicosapentaenoic. PMID: 19638488 Ref: Adenovirus-mediated down-regulation of X-linked inhibitor of apoptosis protein inhibits colon cancer. PMID: 19737940 Ref: Expression of X-linked inhibitor of apoptosis protein in human colorectal cancer and its correlation with prognosis. PMID: 19777490 Ref: A combination of indol-3-carbinol and genistein synergistically induces apoptosis in human colon cancer HT-29 cells by inhibiting Akt phosphorylation and progression of autophagy. PMID: 19909554 |
Ref: Nutlin-3 enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through up-regulation of death receptor 5 (DR5) in human sarcoma HOS cells and human colon cancer HCT116 cells. PMID: 19577358 Ref: Lysosomal destabilization and cathepsin B contributes for cytochrome c release and caspase activation in embelin-induced apoptosis. PMID: 19943316 Ref: Tumor suppressor XIAP-Associated factor 1 (XAF1) cooperates with tumor necrosis factor-related apoptosis-inducing ligand to suppress colon cancer growth and trigger tumor regression. PMID: 20082449 Ref: Synergistic antitumor effect of TRAIL in combination with sunitinib in vitro and in vivo. PMID: 20137855 Ref: beta-Ionone enhances TRAIL-induced apoptosis in hepatocellular carcinoma cells through Sp1-dependent upregulation of DR5 and downregulation of NF-kappaB activity. PMID: 20354117 Ref: Histone deacetylase inhibitors and 15-deoxy-Delta12,14-prostaglandin J2 synergistically induce apoptosis. PMID: 20371690 Ref: Dauricine induces apoptosis, inhibits proliferation and invasion through inhibiting NF-kappaB signaling pathway in colon cancer cells. PMID: 20509140 Ref: In vitro and in vivo radiosensitization of colorectal cancer HT-29 cells by the smac mimetic JP-1201. PMID: 20633731 Ref: Gossypol induces death receptor-5 through activation of the ROS-ERK-CHOP pathway and sensitizes colon cancer cells to TRAIL. PMID: 20837473 Ref: Effects of the HDAC inhibitor CG2 in combination with irinotecan, 5-fluorouracil, or oxaliplatin on HCT116 colon cancer cells and xenografts. PMID: 21042746 Ref: XIAP impairs Smac release from the mitochondria during apoptosis. PMID: 21364655 |
Ref: Sequential caspase-2 and caspase-8 activation is essential for saikosaponin a-induced apoptosis of human colon carcinoma cell lines. PMID: 21107704 Ref: Dimerization of Smac is crucial for its mitochondrial retention by XIAP subsequent to mitochondrial outer membrane permeabilization. PMID: 21354220 Ref: Therapeutic potential and molecular mechanism of a novel, potent, nonpeptide, Smac mimetic SM-164 in combination with TRAIL for cancer treatment. PMID: 21372226 Ref: Methyl jasmonate down-regulates survivin expression and sensitizes colon carcinoma cells towards TRAIL-induced cytotoxicity. PMID: 21486277 Ref: Concomitant activation of caspase-9 and down-regulation of IAP proteins as a mechanism of apoptotic death in HepG2, T47D and HCT-116 cells upon exposure to a derivative from 4-aryl-4H-chromenes family. PMID: 21565459 Ref: Calbindin 2 (CALB2) regulates 5-fluorouracil sensitivity in colorectal cancer by modulating the intrinsic apoptotic pathway. PMID: 21629658 Ref: The orphan nuclear receptor EAR2 is overexpressed in colorectal cancer and it regulates survivability of colon cancer cells. PMID: 21696885 Ref: The effect of combining interferon-alpha and gefitinib in human colon cancer cell lines. PMID: 21942111 Ref: Induction of apoptosis in the SW620 colon carcinoma cell line by triterpene-enriched extracts from Ganoderma lucidum through activation of caspase-3. PMID: 22866120 |
Ref: Knockdown of RON inhibits AP-1 activity and induces apoptosis and cell cycle arrest through the modulation of Akt/FoxO signaling in human colorectal cancer cells. PMID: 21901254 Ref: Clinical application of a systems model of apoptosis execution for the prediction of colorectal cancer therapy responses and personalisation of therapy. PMID: 22082587 Ref: Apoptosome-dependent caspase activation proteins as prognostic markers in Stage II and III colorectal cancer. PMID: 22481083 Ref: Ursodeoxycholic acid protects colon cancer HCT116 cells from deoxycholic acid-induced apoptosis by inhibiting apoptosome formation. PMID: 22497644 Ref: The flavonolignan silibinin potentiates TRAIL-induced apoptosis in human colon adenocarcinoma and in derived TRAIL-resistant metastatic cells. PMID: 22555452 Ref: Transforming growth factor-beta suppresses metastasis in a subset of human colon carcinoma cells. PMID: 22672900 Ref: Systems analysis of cancer cell heterogeneity in caspase-dependent apoptosis subsequent to mitochondrial outer membrane permeabilization. PMID: 23038270 |
Ref: Casticin, a flavonoid, potentiates TRAIL-induced apoptosis through modulation of anti-apoptotic proteins and death receptor 5 in colon cancer cells. PMID: 23135489 Ref: External Qi of Yan Xin Qigong inhibits activation of Akt, Erk1/2 and NF-kB and induces cell cycle arrest and apoptosis in colorectal cancer cells. PMID: 23363659 Ref: The detergent-soluble cytoplasmic pool of survivin suppresses anoikis and its expression is associated with metastatic disease of human colon cancer. PMID: 23405201 Ref: Delivery of sTRAIL variants by MSCs in combination with cytotoxic drug treatment leads to p53-independent enhanced antitumor effects. PMID: 23429289 Ref: Synergistic anticancer effects of curcumin and resveratrol in Hepa1-6 hepatocellular carcinoma cells. PMID: 23446753 Ref: Sanguinarine induces apoptosis in human colorectal cancer HCT-116 cells through ROS-mediated Egr-1 activation and mitochondrial dysfunction. PMID: 23660334 Ref: Hydroxycamptothecin induces apoptosis and inhibits tumor growth in colon cancer by the downregulation of survivin and XIAP expression. PMID: 23721525 Ref: Aldose reductase inhibition enhances TRAIL-induced human colon cancer cell apoptosis through AKT/FOXO3a-dependent upregulation of death receptors. PMID: 23732517 Ref: Teng-Long-Bu-Zhong-Tang, a Chinese herbal formula, enhances anticancer effects of 5--Fluorouracil in CT26 colon carcinoma. PMID: 23758730 Ref: Double targeting of Survivin and XIAP radiosensitizes 3D grown human colorectal tumor cells and decreases migration. PMID: 23830189 Ref: Combining trail with PI3 kinase or HSP90 inhibitors enhances apoptosis in colorectal cancer cells via suppression of survival signaling. PMID: 23852390 Ref: Midazolam induces cellular apoptosis in human cancer cells and inhibits tumor growth in xenograft mice. PMID: 24008365 Ref: Differential PKA activation and AKAP association determines cell fate in cancer cells. PMID: 24083380 Ref: The association of TP53 mutations with the resistance of colorectal carcinoma to the insulin-like growth factor-1 receptor inhibitor picropodophyllin. PMID: 24182354 |
Ref: Down-regulation of BAX gene during carcinogenesis and acquisition of resistance to 5-FU in colorectal cancer. PMID: 24122668 Ref: In vivo analysis of insulin-like growth factor type 1 receptor humanized monoclonal antibody MK-0646 and small molecule kinase inhibitor OSI-906 in colorectal cancer. PMID: 24173770 Ref: Total alkaloids of Tripterygium hypoglaucum (levl.) Hutch inhibits tumor growth both in vitro and in vivo. PMID: 24212079 Ref: Expression of apoptosis regulating proteins identifies stage II and III colon cancer patients with high risk of recurrence. PMID: 24249458 Ref: Ceramide targets xIAP and cIAP1 to sensitize metastatic colon and breast cancer cells to apoptosis induction to suppress tumor progression. PMID: 24422988 Ref: Ezrin expression and cell survival regulation in colorectal cancer. PMID: 24462708 Ref: Akt inhibitor MK-2206 promotes anti-tumor activity and cell death by modulation of AIF and Ezrin in colorectal cancer. PMID: 24581231 Ref: Embelin reduces colitis-associated tumorigenesis through limiting IL-6/STAT3 signaling. PMID: 24651526 Ref: Cysteine-conjugated metabolites of ginger components, shogaols, induce apoptosis through oxidative stress-mediated p53 pathway in human colon cancer cells. PMID: 24786146 Ref: Cracking the cytotoxicity code: apoptotic induction of 10-acetylirciformonin B is mediated through ROS generation and mitochondrial dysfunction. PMID: 24857964 Ref: DHA-mediated enhancement of TRAIL-induced apoptosis in colon cancer cells is associated with engagement of mitochondria and specific alterations in sphingolipid metabolism. PMID: 24953781 Ref: 6-Acetonyldihydrochelerythrine Is a Potent Inducer of Apoptosis in HCT116 and SW620 Colon Cancer Cells. PMID: 25066282 Ref: Aldose reductase inhibition suppresses azoxymethane-induced colonic premalignant lesions in C57BL/KsJ-db/db mice. PMID: 25218594 Ref: MiR-194 deregulation contributes to colorectal carcinogenesis via targeting AKT2 pathway. PMID: 25285168 Ref: Differential control of growth, apoptotic activity and gene expression in human colon cancer cells by extracts derived from medicinal herbs, Rhazya stricta and Zingiber officinale and their combination. PMID: 25386076 Ref: XIAP-targeting drugs re-sensitize PIK3CA-mutated colorectal cancer cells for death receptor-induced apoptosis. PMID: 25501831 |
Ref: Usefulness of alternate-day administration of S-1 and leucovorin in a xenograft mouse model of colorectal cancer: a shorter drug-free interval leads to more efficient antitumor effects. PMID: 24802097 Ref: The Gbeta5 protein regulates sensitivity to TRAIL-induced cell death in colon carcinoma. PMID: 25043307 Ref: Chemopreventive effects of standardized ethanol extract from the aerial parts of Artemisia princeps Pampanini cv. Sajabal via NF-kappaB inactivation on colitis-associated colon tumorigenesis in mice. PMID: 25449198 Ref: Indirect modulation of sensitivity to 5-fluorouracil by microRNA-96 in human colorectal cancer cells. PMID: 25502560 Ref: Biocompatible iota-carrageenan-gamma-maghemite nanocomposite for biomedical applications - synthesis, characterization and in vitro anticancer efficacy. PMID: 25890231 Ref: Cellular prion protein contributes to LS 174T colon cancer cell carcinogenesis by increasing invasiveness and resistance against doxorubicin-induced apoptosis. PMID: 25983001 Ref: High levels of X-linked Inhibitor-of-Apoptosis Protein (XIAP) are indicative of radio chemotherapy resistance in rectal cancer. PMID: 26071313 Ref: CRNDE affects the malignant biological characteristics of human glioma stem cells by negatively regulating miR-186. PMID: 26231038 Ref: MicroRNA-587 antagonizes 5-FU-induced apoptosis and confers drug resistance by regulating PPP2R1B expression in colorectal cancer. PMID: 26247730 Ref: LNA aptamer based multi-modal, Fe3O4-saturated lactoferrin (Fe3O4-bLf) nanocarriers for triple positive (EpCAM, CD133, CD44) colon tumor targeting and NIR, MRI and CT imaging. PMID: 26318819 Ref: The SMAC mimetic BV6 sensitizes colorectal cancer cells to ionizing radiation by interfering with DNA repair processes and enhancing apoptosis. PMID: 26383618 Ref: A-kinase anchor protein 4 (AKAP4) a promising therapeutic target of colorectal cancer. PMID: 26590805 |
Ref: Crude extract of Rheum palmatum L. Induces cell cycle arrest S phase and apoptosis through mitochondrial-dependent pathways in U-2 OS human osteosarcoma cells. PMID: 25689151 Ref: The probiotic Propionibacterium freudenreichii as a new adjuvant for TRAIL-based therapy in colorectal cancer. PMID: 26771233 Ref: Flavokawain C Inhibits Cell Cycle and Promotes Apoptosis, Associated with Endoplasmic Reticulum Stress and Regulation of MAPKs and Akt Signaling Pathways in HCT 116 Human Colon Carcinoma Cells. PMID: 26859847 Ref: The X-linked inhibitor of apoptosis protein is an independent prognostic marker for rectal adenocarcinoma after preoperative chemoradiotherapy. PMID: 26915033 Ref: Bakuchiol sensitizes cancer cells to TRAIL through ROS- and JNK-mediated upregulation of death receptors and downregulation of survival proteins. PMID: 27033605 Ref: Hypoxia regulates TRAIL sensitivity of colorectal cancer cells through mitochondrial autophagy. PMID: 27166192 Ref: MicroRNA-874 inhibits growth, induces apoptosis and reverses chemoresistance in colorectal cancer by targeting X-linked inhibitor of apoptosis protein. PMID: 27221209 Ref: Isoledene from Mesua ferrea oleo-gum resin induces apoptosis in HCT 116 cells through ROS-mediated modulation of multiple proteins in the apoptotic pathways: A mechanistic study. PMID: 27268964 Ref: Enhanced TLR4 Expression on Colon Cancer Cells After Chemotherapy Promotes Cell Survival and Epithelial-Mesenchymal Transition Through Phosphorylation of GSK3beta. PMID: 27354597 Ref: Specific inhibition of p110alpha subunit of PI3K: putative therapeutic strategy for KRAS mutant colorectal cancers. PMID: 27602501 Ref: (3'R)-hydroxytabernaelegantine C: A bisindole alkaloid with potent apoptosis inducing activity in colon (HCT116, SW620) and liver (HepG2) cancer cells. PMID: 27616029 Ref: Evaluation of a furochromone from the halophyte Corydalis heterocarpa for cytotoxic activity against human gastric cancer (AGS) cells. PMID: 27808331 Ref: Death receptor 5 (DR5) and a 5-gene apoptotic biomarker panel with significant differential diagnostic potential in colorectal cancer. PMID: 27827395 Ref: STAT1 Promotes KRAS Colon Tumor Growth and Susceptibility to Pharmacological Inhibition of Translation Initiation Factor eIF4A. PMID: 27913706 |
Ref: BTG1 might be employed as a biomarker for carcinogenesis and a target for gene therapy in colorectal cancers. PMID: 27447746 Ref: Inhibitor of Apoptosis Protein-1 Regulates Tumor Necrosis Factor-Mediated Destruction of Intestinal Epithelial Cells. PMID: 27889570 Ref: Downregulation of microRNA-100/microRNA-125b is associated with lymph node metastasis in early colorectal cancer with submucosal invasion. PMID: 28032929 Ref: Tetraarsenic hexoxide induces G2/M arrest, apoptosis, and autophagy via PI3K/Akt suppression and p38 MAPK activation in SW620 human colon cancer cells. PMID: 28355296 Ref: The suppressing effects of BTG3 expression on aggressive behaviors and phenotypes of colorectal cancer: An in vitro and vivo study. PMID: 28407690 Ref: TGFbeta/Smad3 regulates proliferation and apoptosis through IRS-1 inhibition in colon cancer cells. PMID: 28414818 Ref: Identification of XAF1-MT2A mutual antagonism as a molecular switch in cell-fate decisions under stressful conditions. PMID: 28507149 Ref: miR-15b-5p resensitizes colon cancer cells to 5-fluorouracil by promoting apoptosis via the NF-kappaB/XIAP axis. PMID: 28646148 Ref: Induction of apoptosis by Dae-Hwang-Mok-Dan-Tang in HCT-116 colon cancer cells through activation of caspases and inactivation of the phosphatidylinositol 3-kinase/Akt signaling. PMID: 28664141 Ref: HtrA1 Down-regulation Induces Cisplatin Resistance in Colon Cancer by Increasing XIAP and Activating PI3K/Akt Pathway. PMID: 28667026 Ref: Evaluation of the Expression of the Inhibitor of Apoptosis Protein Family and Human Telomerase Reverse Transcriptase in Patients With Advanced Colorectal Adenoma. PMID: 28698863 Ref: Malformin A1 treatment alters invasive and oncogenic phenotypes of human colorectal cancer cells through stimulation of the p38 signaling pathway. PMID: 28713983 Ref: SATB2/beta-catenin/TCF-LEF pathway induces cellular transformation by generating cancer stem cells in colorectal cancer. PMID: 28887549 |
Ref: Comparison of the effect of chemical composition of anthocyanin-rich plant extracts on colon cancer cell proliferation and their potential mechanism of action using in vitro, in silico, and biochemical assays. PMID: 29037704 Ref: XIAP overexpression promotes bladder cancer invasion in vitro and lung metastasis in vivo via enhancing nucleolin-mediated Rho-GDIbeta mRNA stability. PMID: 29250796 Ref: The G protein-coupled P2Y(6) receptor promotes colorectal cancer tumorigenesis by inhibiting apoptosis. PMID: 29454075 Ref: TGFbeta and IGF1R signaling activates protein kinase A through differential regulation of ezrin phosphorylation in colon cancer cells. PMID: 29599290 Ref: Varacin-1, a novel analog of varacin C, induces p53-independent apoptosis in cancer cells through ROS-mediated reduction of XIAP. PMID: 29773887 Ref: Bufalin and 5-fluorouracil synergistically induce apoptosis in colorectal cancer cells. PMID: 29849804 Ref: KT2 and RT2 modified antimicrobial peptides derived from Crocodylus siamensis Leucrocin I show activity against human colon cancer HCT-116 cells. PMID: 30031283 Ref: Coptisine-induced apoptosis in human colon cancer cells (HCT-116) is mediated by PI3K/Akt and mitochondrial-associated apoptotic pathway. PMID: 30195873 Ref: XIAP facilitates breast and colon carcinoma growth via promotion of p62 depletion through ubiquitination-dependent proteasomal degradation. PMID: 30275562 |