Primary Site >> Colorectal Cancer

Gene >> VTI1A

Journal: Nat Genet. 2011 Sep 4;43(10):964-8.
Title: Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion.
Author: Bass, Adam J|Lawrence, Michael S|Brace, Lear E|Ramos, Alex H|Drier, Yotam|Cibulskis, Kristian|Sougnez, Carrie|Voet, Douglas|Saksena, Gordon|Sivachenko, Andrey|Jing, Rui|Parkin, Melissa|Pugh, Trevor|Verhaak, Roel G|Stransky, Nicolas|Boutin, Adam T|Barretin
PMID: 21892161
Journal: PLoS One. 2014 Mar 7;9(3):e91264.
Title: High frequency of fusion transcripts involving TCF7L2 in colorectal cancer: novel fusion partner and splice variants.
Author: Nome, Torfinn|Hoff, Andreas M|Bakken, Anne Cathrine|Rognum, Torleiv O|Nesbakken, Arild|Skotheim, Rolf I
PMID: 24608966
Journal: BMC Med Genomics. 2014 Jun 18;7:36.
Title: Whole genome sequencing reveals potential targets for therapy in patients with refractory KRAS mutated metastatic colorectal cancer.
Author: Shanmugam, Vijayalakshmi|Ramanathan, Ramesh K|Lavender, Nicole A|Sinari, Shripad|Chadha, Manpreet|Liang, Winnie S|Kurdoglu, Ahmet|Izatt, Tyler|Christoforides, Alexis|Benson, Hollie|Phillips, Lori|Baker, Angela|Murray, Christopher|Hostetter, Galen|Von Hoff
PMID: 24943349
Journal: Nat Commun. 2014 Aug 8;5:4613.
Title: Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A.
Author: Wang, Hansong|Burnett, Terrilea|Kono, Suminori|Haiman, Christopher A|Iwasaki, Motoki|Wilkens, Lynne R|Loo, Lenora W M|Van Den Berg, David|Kolonel, Laurence N|Henderson, Brian E|Keku, Temitope O|Sandler, Robert S|Signorello, Lisa B|Blot, William J|Newcomb,
PMID: 25105248
Journal: Int J Cancer. 2018 Feb 1;142(3):498-513.
Title: Cumulative evidence for relationships between multiple variants in the VTI1A and TCF7L2 genes and cancer incidence.
Author: Zhang, Min|Tang, Mingshuang|Fang, Yanfei|Cui, Huijie|Chen, Siyu|Li, Junlong|Xiong, Hongyan|Lu, Jiachun|Gu, Dongqing|Zhang, Ben
PMID: 28949031
Journal: PLoS One. 2018 Jul 5;13(7):e0200215.
Title: The VTI1A-TCF4 colon cancer fusion protein is a dominant negative regulator of Wnt signaling and is transcriptionally regulated by intestinal homeodomain factor CDX2.
Author: Davidsen, Johanne|Larsen, Sylvester|Coskun, Mehmet|Gogenur, Ismail|Dahlgaard, Katja|Bennett, Eric Paul|Troelsen, Jesper Thorvald
PMID: 29975781