Primary Site >> Colorectal Cancer
Gene >> VTI1A
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Ref: Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion. PMID: 21892161 |
Ref: High frequency of fusion transcripts involving TCF7L2 in colorectal cancer: novel fusion partner and splice variants. PMID: 24608966 Ref: Whole genome sequencing reveals potential targets for therapy in patients with refractory KRAS mutated metastatic colorectal cancer. PMID: 24943349 Ref: Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A. PMID: 25105248 |
Ref: Cumulative evidence for relationships between multiple variants in the VTI1A and TCF7L2 genes and cancer incidence. PMID: 28949031 Ref: The VTI1A-TCF4 colon cancer fusion protein is a dominant negative regulator of Wnt signaling and is transcriptionally regulated by intestinal homeodomain factor CDX2. PMID: 29975781 |