Primary Site >> Colorectal Cancer
Gene >> VHL
| 1. | |||||||||||
| Journal: | World J Urol. 1994;12(3):162-8. | ||||||||||
| Title: | Genetic alterations in sporadic renal-cell carcinoma: molecular analyses of tumor suppressor gene harboring chromosomal regions 3p, 5q, and 17p. | ||||||||||
| Author: | Brauch, H|Pomer, S|Hieronymus, T|Schadt, T|Lohrke, H|Komitowski, D | ||||||||||
| PMID: | 7951344 | ||||||||||
| 2. | |||||||||||
| Journal: | Am J Pathol. 1995 Mar;146(3):620-5. | ||||||||||
| Title: | A microdissection technique for archival DNA analysis of specific cell populations in lesions < 1 mm in size. | ||||||||||
| Author: | Zhuang, Z|Bertheau, P|Emmert-Buck, M R|Liotta, L A|Gnarra, J|Linehan, W M|Lubensky, I A | ||||||||||
| PMID: | 7887444 | ||||||||||
| 3. | |||||||||||
| Journal: | Hum Pathol. 1996 Feb;27(2):165-71. | ||||||||||
| Title: | Genetic analysis of synchronous mucinous tumors of the ovary and appendix. | ||||||||||
| Author: | Chuaqui, R F|Zhuang, Z|Emmert-Buck, M R|Bryant, B R|Nogales, F|Tavassoli, F A|Merino, M J | ||||||||||
| PMID: | 8617458 | ||||||||||
| 4. | |||||||||||
| Journal: | Chin Med Sci J. 1996 Mar;11(1):36-40. | ||||||||||
| Title: | Analysis of the N-glycosylation of the serum glycoproteins defined by Con A, PHA-E, RCA1 and WGA in Chinese patients with gastrointestinal diseases. | ||||||||||
| Author: | Zhang, J|Chen, Y|Dai, X|Wang, S | ||||||||||
| PMID: | 9206117 | ||||||||||
| 5. | |||||||||||
| Journal: | Hum Pathol. 1996 Feb;27(2):152-6. | ||||||||||
| Title: | von Hippel-Lindau disease gene deletion detected in microdissected sporadic human colon carcinoma specimens. | ||||||||||
| Author: | Zhuang, Z|Emmert-Buck, M R|Roth, M J|Gnarra, J|Linehan, W M|Liotta, L A|Lubensky, I A | ||||||||||
| PMID: | 8617456 | ||||||||||
| 6. | |||||||||||
| Journal: | Arch Ital Urol Androl. 1997 Sep;69(4):241-6. | ||||||||||
| Title: | [Heredity in renal and prostatic neoplasia]. | ||||||||||
| Author: | Prayer Galetti, T|D'Arrigo, L|De Zorzi, L|Patarnello, T | ||||||||||
| PMID: | 9417296 | ||||||||||
| 7. | |||||||||||
| Journal: | Oncogene. 2002 Mar 14;21(12):1909-21. | ||||||||||
| Title: | An endonuclease/ligase based mutation scanning method especially suited for analysis of neoplastic tissue. | ||||||||||
| Author: | Huang, Jianmin|Kirk, Brian|Favis, Reyna|Soussi, Thierry|Paty, Philip|Cao, Weiguo|Barany, Francis | ||||||||||
| PMID: | 11896624 | ||||||||||
| 8. | |||||||||||
| Journal: | Mol Cancer Ther. 2003 Mar;2(3):235-43. | ||||||||||
| Title: | The thioredoxin redox inhibitors 1-methylpropyl 2-imidazolyl disulfide and pleurotin inhibit hypoxia-induced factor 1alpha and vascular endothelial growth factor formation. | ||||||||||
| Author: | Welsh, Sarah J|Williams, Ryan R|Birmingham, Anne|Newman, David J|Kirkpatrick, D Lynn|Powis, Garth | ||||||||||
| PMID: | 12657718 | ||||||||||
| 9. | |||||||||||
| Journal: | |||||||||||
| Title: | (125)I-Labeled mouse anti-human carbonic anhydrase IX monoclonal antibody | ||||||||||
| Author: | Shan, Liang | ||||||||||
| PMID: | 22675743 | ||||||||||
| 10. | |||||||||||
| Journal: | World J Gastroenterol. 2004 Dec 1;10(23):3441-54. | ||||||||||
| Title: | Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis. | ||||||||||
| Author: | Xu, Xiao-Li|Yu, Jian|Zhang, Hong-Yu|Sun, Meng-Hong|Gu, Jun|Du, Xiang|Shi, Da-Ren|Wang, Peng|Yang, Zhen-Hua|Zhu, Jing-De | ||||||||||
| PMID: | 15526363 | ||||||||||
| 11. | |||||||||||
| Journal: | Hum Pathol. 2004 Sep;35(9):1105-11. | ||||||||||
| Title: | Loss of heterozygosity reveals non-VHL allelic loss in hemangioblastomas at 22q13. | ||||||||||
| Author: | Beckner, Marie E|Sasatomi, Eizaburo|Swalsky, Patricia A|Hamilton, Ronald L|Pollack, Ian F|Finkelstein, Sydney D | ||||||||||
| PMID: | 15343513 | ||||||||||
| 12. | |||||||||||
| Journal: | Nihon Rinsho. 2004 May;62(5):851-63. | ||||||||||
| Title: | [Familial tumor syndrome and ectopic hormone-producing tumors]. | ||||||||||
| Author: | Tamura, Kazuo|Utsunomiya, Joji|Yamamura, Takehira | ||||||||||
| PMID: | 15148809 | ||||||||||
| 13. | |||||||||||
| Journal: | Cancer Sci. 2004 Feb;95(2):149-53. | ||||||||||
| Title: | Mutation of the von Hippel-Lindau (VHL) gene in human colorectal carcinoma: association with cytoplasmic accumulation of hypoxia-inducible factor (HIF)-1alpha. | ||||||||||
| Author: | Kuwai, Toshio|Kitadai, Yasuhiko|Tanaka, Shinji|Hiyama, Toru|Tanimoto, Keiji|Chayama, Kazuaki | ||||||||||
| PMID: | 14965365 | ||||||||||
| 14. | |||||||||||
| Journal: | Mod Pathol. 2005 Feb;18(2):170-8. | ||||||||||
| Title: | Progressive methylation during the serrated neoplasia pathway of the colorectum. | ||||||||||
| Author: | Dong, Seung M|Lee, Eui J|Jeon, Eun S|Park, Cheol K|Kim, Kyoung-Mee | ||||||||||
| PMID: | 15389252 | ||||||||||
| 15. | |||||||||||
| Journal: | World J Gastroenterol. 2005 May 7;11(17):2616-25. | ||||||||||
| Title: | Expression of von Hippel-Lindau tumor suppressor and tumor-associated carbonic anhydrases IX and XII in normal and neoplastic colorectal mucosa. | ||||||||||
| Author: | Kivela, Antti-J|Parkkila, Seppo|Saarnio, Juha|Karttunen, Tuomo-J|Kivela, Jyrki|Parkkila, Anna-Kaisa|Bartosova, Maria|Mucha, Vojtech|Novak, Michal|Waheed, Abdul|Sly, William-S|Rajaniemi, Hannu|Pastorekova, Silvia|Pastorek, Jaromir | ||||||||||
| PMID: | 15849821 | ||||||||||
| 16. | |||||||||||
| Journal: | Oncogene. 2006 May 18;25(21):3065-70. | ||||||||||
| Title: | Interplay between VHL/HIF1alpha and Wnt/beta-catenin pathways during colorectal tumorigenesis. | ||||||||||
| Author: | Giles, R H|Lolkema, M P|Snijckers, C M|Belderbos, M|van der Groep, P|Mans, D A|van Beest, M|van Noort, M|Goldschmeding, R|van Diest, P J|Clevers, H|Voest, E E | ||||||||||
| PMID: | 16407833 | ||||||||||
| 17. | |||||||||||
| Journal: | Nat Med. 2006 Jul;12(7):809-16. | ||||||||||
| Title: | E2-EPF UCP targets pVHL for degradation and associates with tumor growth and metastasis. | ||||||||||
| Author: | Jung, Cho-Rok|Hwang, Kyung-Sun|Yoo, Jinsang|Cho, Won-Kyung|Kim, Jin-Man|Kim, Woo Ho|Im, Dong-Soo | ||||||||||
| PMID: | 16819549 | ||||||||||
| 18. | |||||||||||
| Journal: | Mol Carcinog. 2006 Nov;45(11):833-40. | ||||||||||
| Title: | Association between ulcerative growth and hypoxia inducible factor-1alpha polymorphisms in colorectal cancer patients. | ||||||||||
| Author: | Fransen, Karin|Fenech, Matthew|Fredrikson, Mats|Dabrosin, Charlotta|Soderkvist, Peter | ||||||||||
| PMID: | 16865676 | ||||||||||
| 19. | |||||||||||
| Journal: | Mutat Res. 2008 Jan-Feb;658(1-2):42-54. | ||||||||||
| Title: | Etiologic impact of known cancer susceptibility genes. | ||||||||||
| Author: | Hemminki, Kari|Forsti, Asta|Lorenzo Bermejo, Justo | ||||||||||
| PMID: | 17827054 | ||||||||||
| 20. | |||||||||||
| Journal: | Int J Cancer. 2008 Mar 15;122(6):1435-40. | ||||||||||
| Title: | Extracellular matrix and HIF-1 signaling: the role of prolidase. | ||||||||||
| Author: | Surazynski, Arkadiusz|Donald, Steven P|Cooper, Sandra K|Whiteside, Martin A|Salnikow, Konstantin|Liu, Yongmin|Phang, James M | ||||||||||
| PMID: | 17999410 | ||||||||||
| 21. | |||||||||||
| Journal: | Z Gastroenterol. 2008 Oct;46(10):1202-6. | ||||||||||
| Title: | [Epigenetic alterations in colorectal carcinomas and precancerous lesions]. | ||||||||||
| Author: | Tischoff, I|Tannapfel, A | ||||||||||
| PMID: | 18937191 | ||||||||||
| 22. | |||||||||||
| Journal: | APMIS. 2009 Dec;117(12):880-5. | ||||||||||
| Title: | Mutational analysis of hypoxia-related genes HIF1alpha and CUL2 in common human cancers. | ||||||||||
| Author: | Park, Sang Wook|Chung, Nak Gyun|Hur, Soo Young|Kim, Ho Shik|Yoo, Nam Jin|Lee, Sug Hyung | ||||||||||
| PMID: | 20078552 | ||||||||||
| 23. | |||||||||||
| Journal: | Eur J Surg Oncol. 2009 Dec;35(12):1286-94. | ||||||||||
| Title: | Expression patterns of hypoxic markers at the invasive margin of colorectal cancers and liver metastases. | ||||||||||
| Author: | Rajaganeshan, R|Prasad, R|Guillou, P J|Scott, N|Poston, G|Jayne, D G | ||||||||||
| PMID: | 19540709 | ||||||||||
| 24. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2009 Feb 6;379(2):583-8. | ||||||||||
| Title: | Human selenium binding protein-1 (hSP56) interacts with VDU1 in a selenium-dependent manner. | ||||||||||
| Author: | Jeong, Jee-Yeong|Wang, Yuxun|Sytkowski, Arthur J | ||||||||||
| PMID: | 19118533 | ||||||||||
| 25. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2010 Jul 23;398(2):205-11. | ||||||||||
| Title: | Sunitinib deregulates tumor adaptation to hypoxia by inhibiting HIF-1alpha synthesis in HT-29 colon cancer cells. | ||||||||||
| Author: | Shin, Hyun-Woo|Cho, Chung-Hyun|Kim, Tae-You|Park, Jong-Wan | ||||||||||
| PMID: | 20599738 | ||||||||||
| 26. | |||||||||||
| Journal: | Biochem Pharmacol. 2010 Oct 1;80(7):982-9. | ||||||||||
| Title: | LW6, a novel HIF-1 inhibitor, promotes proteasomal degradation of HIF-1alpha via upregulation of VHL in a colon cancer cell line. | ||||||||||
| Author: | Lee, Kyeong|Kang, Jung Eun|Park, Song-Kyu|Jin, Yinglan|Chung, Kyung-Sook|Kim, Hwan-Mook|Lee, Kiho|Kang, Moo Rim|Lee, Myung Kyu|Song, Kyung Bin|Yang, Eun-Gyeong|Lee, Jung-Jun|Won, Misun | ||||||||||
| PMID: | 20599784 | ||||||||||
| 27. | |||||||||||
| Journal: | Cell Death Dis. 2011 Dec 1;2:e235. | ||||||||||
| Title: | Novel tumor suppressive function of Smad4 in serum starvation-induced cell death through PAK1-PUMA pathway. | ||||||||||
| Author: | Lee, S-H|Jung, Y-S|Chung, J-Y|Oh, A Y|Lee, S-J|Choi, D H|Jang, S M|Jang, K-S|Paik, S S|Ha, N-C|Park, B-J | ||||||||||
| PMID: | 22130069 | ||||||||||
| 28. | |||||||||||
| Journal: | Mol Cell. 2012 Jan 27;45(2):233-43. | ||||||||||
| Title: | Regulation of KLF4 turnover reveals an unexpected tissue-specific role of pVHL in tumorigenesis. | ||||||||||
| Author: | Gamper, Armin M|Qiao, Xinxian|Kim, Jennifer|Zhang, Liyong|DeSimone, Michelle C|Rathmell, W Kimryn|Wan, Yong | ||||||||||
| PMID: | 22284679 | ||||||||||
| 29. | |||||||||||
| Journal: | J Biol Chem. 2012 Apr 20;287(17):13584-97. | ||||||||||
| Title: | Novel insight into KLF4 proteolytic regulation in estrogen receptor signaling and breast carcinogenesis. | ||||||||||
| Author: | Hu, Dong|Zhou, Zhuan|Davidson, Nancy E|Huang, Yi|Wan, Yong | ||||||||||
| PMID: | 22389506 | ||||||||||
| 30. | |||||||||||
| Journal: | Cancer Res. 2012 May 1;72(9):2285-93. | ||||||||||
| Title: | Hypoxia-inducible factor-2alpha activation promotes colorectal cancer progression by dysregulating iron homeostasis. | ||||||||||
| Author: | Xue, Xiang|Taylor, Matthew|Anderson, Erik|Hao, Cathy|Qu, Aijuan|Greenson, Joel K|Zimmermann, Ellen M|Gonzalez, Frank J|Shah, Yatrik M | ||||||||||
| PMID: | 22419665 | ||||||||||
| 31. | |||||||||||
| Journal: | Int J Oncol. 2012 Sep;41(3):793-7. | ||||||||||
| Title: | Epimutation and cancer: a new carcinogenic mechanism of Lynch syndrome (Review). | ||||||||||
| Author: | Banno, Kouji|Kisu, Iori|Yanokura, Megumi|Tsuji, Kosuke|Masuda, Kenta|Ueki, Arisa|Kobayashi, Yusuke|Yamagami, Wataru|Nomura, Hiroyuki|Tominaga, Eiichiro|Susumu, Nobuyuki|Aoki, Daisuke | ||||||||||
| PMID: | 22735547 | ||||||||||
| 32. | |||||||||||
| Journal: | BMC Cancer. 2012 Jul 17;12:293. | ||||||||||
| Title: | Prolyl hydroxylase 2 dependent and Von-Hippel-Lindau independent degradation of Hypoxia-inducible factor 1 and 2 alpha by selenium in clear cell renal cell carcinoma leads to tumor growth inhibition. | ||||||||||
| Author: | Chintala, Sreenivasulu|Najrana, Tanbir|Toth, Karoly|Cao, Shousong|Durrani, Farukh A|Pili, Roberto|Rustum, Youcef M | ||||||||||
| PMID: | 22804960 | ||||||||||
| 33. | |||||||||||
| Journal: | J Biomol Screen. 2013 Aug;18(7):782-96. | ||||||||||
| Title: | A kinome-wide siRNA screen identifies multiple roles for protein kinases in hypoxic stress adaptation, including roles for IRAK4 and GAK in protection against apoptosis in VHL-/- renal carcinoma cells, despite activation of the NF-kappaB pathway. | ||||||||||
| Author: | Pan, Jing|Zhang, Jing|Hill, Andrew|Lapan, Peter|Berasi, Steve|Bates, Brian|Miller, Christopher|Haney, Steven | ||||||||||
| PMID: | 23591012 | ||||||||||
| 34. | |||||||||||
| Journal: | Pathology. 2013 Apr;45(3):316-30. | ||||||||||
| Title: | Precursor lesions of endocrine system neoplasms. | ||||||||||
| Author: | Mete, Ozgur|Asa, Sylvia L | ||||||||||
| PMID: | 23478233 | ||||||||||
| 35. | |||||||||||
| Journal: | Carcinogenesis. 2013 Jan;34(1):163-9. | ||||||||||
| Title: | Hypoxia-inducible factor-2alpha is essential in activating the COX2/mPGES-1/PGE2 signaling axis in colon cancer. | ||||||||||
| Author: | Xue, Xiang|Shah, Yatrik M | ||||||||||
| PMID: | 23042097 | ||||||||||
| 36. | |||||||||||
| Journal: | Int J Cancer. 2014 Jun 1;134(11):2656-62. | ||||||||||
| Title: | Commonality and differences of methylation signatures in the plasma of patients with pancreatic cancer and colorectal cancer. | ||||||||||
| Author: | Melson, Joshua|Li, Yan|Cassinotti, Elisa|Melnikov, Anatoliy|Boni, Luigi|Ai, Junmei|Greenspan, Michael|Mobarhan, Sohrab|Levenson, Victor|Deng, Youping | ||||||||||
| PMID: | 24288256 | ||||||||||
| 37. | |||||||||||
| Journal: | Int J Oncol. 2014 Dec;45(6):2455-67. | ||||||||||
| Title: | Monoclonal antibody G250 targeting CA : Binding specificity, internalization and therapeutic effects in a non-renal cancer model. | ||||||||||
| Author: | Zatovicova, Miriam|Jelenska, Lenka|Hulikova, Alzbeta|Ditte, Peter|Ditte, Zuzana|Csaderova, Lucia|Svastova, Eliska|Schmalix, Wolfgang|Boettger, Volker|Bevan, Paul|Pastorek, Jaromir|Pastorekova, Silvia | ||||||||||
| PMID: | 25230982 | ||||||||||
| 38. | |||||||||||
| Journal: | Cancer Lett. 2015 Aug 10;364(2):156-64. | ||||||||||
| Title: | The BH3-mimetic obatoclax reduces HIF-1alpha levels and HIF-1 transcriptional activity and sensitizes hypoxic colon adenocarcinoma cells to 5-fluorouracil. | ||||||||||
| Author: | Gariboldi, Marzia B|Taiana, Elisa|Bonzi, Maria Chiara|Craparotta, Ilaria|Giovannardi, Stefano|Mancini, Monica|Monti, Elena | ||||||||||
| PMID: | 25979228 | ||||||||||
| 39. | |||||||||||
| Journal: | Virchows Arch. 2016 Oct;469(4):395-404. | ||||||||||
| Title: | HIF-1alpha expression and high microvessel density are characteristic features in serrated colorectal cancer. | ||||||||||
| Author: | Tuomisto, Anne|Garcia-Solano, Jose|Sirnio, Paivi|Vayrynen, Juha|Perez-Guillermo, Miguel|Makinen, Markus J|Conesa-Zamora, Pablo | ||||||||||
| PMID: | 27421843 | ||||||||||
| 40. | |||||||||||
| Journal: | Med Oncol. 2016 Oct;33(10):106. | ||||||||||
| Title: | Targeted molecular profiling of rare genetic alterations in colorectal cancer using next-generation sequencing. | ||||||||||
| Author: | Jauhri, Mayank|Bhatnagar, Akanksha|Gupta, Satish|Shokeen, Yogender|Minhas, Sachin|Aggarwal, Shyam | ||||||||||
| PMID: | 27568332 | ||||||||||
| 41. | |||||||||||
| Journal: | Mol Cancer. 2016 Oct 18;15(1):63. | ||||||||||
| Title: | Spatio-temporal mutation profiles of case-matched colorectal carcinomas and their metastases reveal unique de novo mutations in metachronous lung metastases by targeted next generation sequencing. | ||||||||||
| Author: | Kovaleva, Valentina|Geissler, Anna-Lena|Lutz, Lisa|Fritsch, Ralph|Makowiec, Frank|Wiesemann, Sebastian|Hopt, Ulrich T|Passlick, Bernward|Werner, Martin|Lassmann, Silke | ||||||||||
| PMID: | 27756406 | ||||||||||
| 42. | |||||||||||
| Journal: | J Gen Virol. 2016 Dec;97(12):3174-3182. | ||||||||||
| Title: | Newcastle disease virus degrades HIF-1alpha through proteasomal pathways independent of VHL and p53. | ||||||||||
| Author: | Abd-Aziz, Noraini|Stanbridge, Eric J|Shafee, Norazizah | ||||||||||
| PMID: | 27902314 | ||||||||||
| 43. | |||||||||||
| Journal: | Exp Mol Pathol. 2017 Apr;102(2):255-261. | ||||||||||
| Title: | Detecting circulating tumor DNA in renal cancer: An open challenge. | ||||||||||
| Author: | Corro, Claudia|Hejhal, Tomas|Poyet, Cedric|Sulser, Tullio|Hermanns, Thomas|Winder, Thomas|Prager, Gerald|Wild, Peter J|Frew, Ian|Moch, Holger|Rechsteiner, Markus | ||||||||||
| PMID: | 28214514 | ||||||||||
| 44. | |||||||||||
| Journal: | Am J Physiol Heart Circ Physiol. 2017 Jun 1;312(6):H1154-H1162. | ||||||||||
| Title: | Increased hypoxia-inducible factor-1alpha in striated muscle of tumor-bearing mice. | ||||||||||
| Author: | Devine, Raymond D|Bicer, Sabahattin|Reiser, Peter J|Wold, Loren E | ||||||||||
| PMID: | 28341633 | ||||||||||
| 45. | |||||||||||
| Journal: | Clin Neurol Neurosurg. 2017 Jul;158:46-48. | ||||||||||
| Title: | A rare case of choroid plexus carcinoma that led to the diagnosis of Lynch syndrome (hereditary nonpolyposis colorectal cancer). | ||||||||||
| Author: | Zhu, Viola W|Hinduja, Sanjay|Knezevich, Stevan R|Silveira, William R|DeLozier, Celia D | ||||||||||
| PMID: | 28460341 | ||||||||||