Primary Site >> Colorectal Cancer

Gene >> UNC5C

Journal: Mech Dev. 2002 Oct;118(1-2):191-7.
Title: Cloning of three mouse Unc5 genes and their expression patterns at mid-gestation.
Author: Engelkamp, Dieter
PMID: 12351186
Journal: Int J Cancer. 2003 Jan 20;103(3):306-15.
Title: Quantification of expression of netrins, slits and their receptors in human prostate tumors.
Author: Latil, Alain|Chene, Laurent|Cochant-Priollet, Beatrix|Mangin, Philippe|Fournier, Georges|Berthon, Philippe|Cussenot, Olivier
PMID: 12471613
Journal: Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):4173-8. Epub 2003 Mar 24.
Title: The netrin-1 receptors UNC5H are putative tumor suppressors controlling cell death commitment.
Author: Thiebault, Karine|Mazelin, Laetitia|Pays, Laurent|Llambi, Fabien|Joly, Marie-Odile|Scoazec, Jean-Yves|Saurin, Jean-Christophe|Romeo, Giovanni|Mehlen, Patrick
PMID: 12655055
Journal: Int J Dev Biol. 2007;51(5):409-13.
Title: Analysis of Netrin 1 receptors during inner ear development.
Author: Matilainen, Tanja|Haugas, Maarja|Kreidberg, Jordan A|Salminen, Marjo
PMID: 17616930
Journal: Gastroenterology. 2007 Dec;133(6):1840-8. Epub 2007 Aug 2.
Title: Inactivation of the UNC5C Netrin-1 receptor is associated with tumor progression in colorectal malignancies.
Author: Bernet, Agnes|Mazelin, Laetitia|Coissieux, Marie-May|Gadot, Nicolas|Ackerman, Susan L|Scoazec, Jean-Yves|Mehlen, Patrick
PMID: 17967459
Journal: Gastroenterology. 2007 Dec;133(6):1849-57. Epub 2007 Sep 5.
Title: Epigenetic and genetic alterations in Netrin-1 receptors UNC5C and DCC in human colon cancer.
Author: Shin, Sung Kwan|Nagasaka, Takeshi|Jung, Barbara H|Matsubara, Nagahide|Kim, Won Ho|Carethers, John M|Boland, C Richard|Goel, Ajay
PMID: 18054557
Journal: Gastroenterology. 2008 Oct;135(4):1248-57.
Title: NF-kappaB regulates netrin-1 expression and affects the conditional tumor suppressive activity of the netrin-1 receptors.
Author: Paradisi, Andrea|Maisse, Carine|Bernet, Agnes|Coissieux, Marie-May|Maccarrone, Mauro|Scoazec, Jean-Yves|Mehlen, Patrick
PMID: 18692059
Journal: Anticancer Res. 2009 Nov;29(11):4397-9.
Title: Changes in UNC5C gene methylation during human gastric carcinogenesis.
Author: Hibi, Kenji|Sakata, Makiko|Sakuraba, Kazuma|Kitamura, Yo-Hei|Shirahata, Atsushi|Goto, Tetsuhiro|Mizukami, Hiroki|Saito, Mitsuo|Ishibashi, Kazuyoshi|Kigawa, Gaku|Nemoto, Hiroshi|Sanada, Yutaka
PMID: 20032384
Journal: Am J Nephrol. 2009;30(3):186-93.
Title: Segment-specific expression of netrin-1 receptors in normal and ischemic mouse kidney.
Author: Wang, Weiwei|Ramesh, Ganesan
PMID: 19372643
Journal: Anticancer Res. 2009 Jan;29(1):271-3.
Title: Aberrant methylation of the UNC5C gene is frequently detected in advanced colorectal cancer.
Author: Hibi, Kenji|Mizukami, Hiroki|Shirahata, Atsushi|Goto, Tetsuhiro|Sakata, Makiko|Saito, Mitsuo|Ishibashi, Kazuyoshi|Kigawa, Gaku|Nemoto, Hiroshi|Sanada, Yutaka
PMID: 19331160
Journal: World J Surg. 2009 May;33(5):1053-7.
Title: Aberrant methylation of the netrin-1 receptor genes UNC5C and DCC detected in advanced colorectal cancer.
Author: Hibi, Kenji|Mizukami, Hiroki|Shirahata, Atsushi|Goto, Tetsuhiro|Sakata, Makiko|Sanada, Yutaka
PMID: 19242752
Journal: Am J Physiol Renal Physiol. 2009 Apr;296(4):F723-9.
Title: Netrin-1 increases proliferation and migration of renal proximal tubular epithelial cells via the UNC5B receptor.
Author: Wang, Weiwei|Reeves, W Brian|Ramesh, Ganesan
PMID: 19211685
Journal: J Immunol. 2010 Sep 15;185(6):3750-8.
Title: Netrin-1 regulates Th1/Th2/Th17 cytokine production and inflammation through UNC5B receptor and protects kidney against ischemia-reperfusion injury.
Author: Tadagavadi, Raghu Kempegowda|Wang, Weiwei|Ramesh, Ganesan
PMID: 20693423
Journal: Gastroenterology. 2011 Dec;141(6):2039-46.
Title: Variants in the netrin-1 receptor UNC5C prevent apoptosis and increase risk of familial colorectal cancer.
Author: Coissieux, Marie-May|Tomsic, Jerneja|Castets, Marie|Hampel, Heather|Tuupanen, Sari|Andrieu, Nadine|Comeras, Ilene|Drouet, Youenn|Lasset, Christine|Liyanarachchi, Sandya|Mazelin, Laetitia|Puisieux, Alain|Saurin, Jean-Christophe|Scoazec, Jean-Yves|Wang, Qin
PMID: 21893118
Journal: Invest Ophthalmol Vis Sci. 2012 Mar 9;53(3):1285-95.
Title: Netrin-1 simultaneously suppresses corneal inflammation and neovascularization.
Author: Han, Yun|Shao, Yi|Lin, Zhirong|Qu, Yang-Luowa|Wang, He|Zhou, Yueping|Chen, Wensheng|Chen, Yongxiong|Chen, Wei-Li|Hu, Fung-Rong|Li, Wei|Liu, Zuguo
PMID: 22323486
Journal: J Biol Chem. 2012 Aug 3;287(32):27126-38.
Title: Down syndrome cell adhesion molecule (DSCAM) associates with uncoordinated-5C (UNC5C) in netrin-1-mediated growth cone collapse.
Author: Purohit, Anish A|Li, Weiquan|Qu, Chao|Dwyer, Trisha|Shao, Qiangqiang|Guan, Kun-Liang|Liu, Guofa
PMID: 22685302
Journal: Immunopharmacol Immunotoxicol. 2013 Oct;35(5):581-93.
Title: Prenatal activation of maternal TLR3 receptors by viral-mimetic poly(I:C) modifies GluN2B expression in embryos and sonic hedgehog in offspring in the absence of kynurenine pathway activation.
Author: Khalil, Omari S|Forrest, Caroline M|Pisar, Mazura|Smith, Robert A|Darlington, L Gail|Stone, Trevor W
PMID: 23981041
Journal: World J Gastroenterol. 2014 Jan 7;20(1):204-13.
Title: Evaluation of the colorectal cancer risk conferred by rare UNC5C alleles.
Author: Kury, Sebastien|Garrec, Celine|Airaud, Fabrice|Breheret, Flora|Guibert, Virginie|Frenard, Cecile|Jiao, Shuo|Bonneau, Dominique|Berthet, Pascaline|Bossard, Celine|Ingster, Olivier|Cauchin, Estelle|Bezieau, Stephane
PMID: 24415873
Journal: Psychopharmacology (Berl). 2015 Oct;232(20):3719-29.
Title: Resilience to amphetamine in mouse models of netrin-1 haploinsufficiency: role of mesocortical dopamine.
Author: Pokinko, Matthew|Moquin, Luc|Torres-Berrio, Angelica|Gratton, Alain|Flores, Cecilia
PMID: 26264903
Journal: Sci Rep. 2016 Feb 8;6:20697.
Title: Scarce evidence of the causal role of germline mutations in UNC5C in hereditary colorectal cancer and polyposis.
Author: Mur, Pilar|Sanchez-Cuartielles, Elena|Ausso, Susanna|Aiza, Gemma|Valdes-Mas, Rafael|Pineda, Marta|Navarro, Matilde|Brunet, Joan|Urioste, Miguel|Lazaro, Conxi|Moreno, Victor|Capella, Gabriel|Puente, Xose S|Valle, Laura
PMID: 26852919
Journal: Sci Rep. 2016 Apr 20;6:23880.
Title: Erratum: Scarce evidence of the causal role of germline mutations in UNC5C in hereditary colorectal cancer and polyposis.
Author: Mur, Pilar|Sanchez-Cuartielles, Elena|Ausso, Susanna|Aiza, Gemma|Valdes-Mas, Rafael|Pineda, Marta|Navarro, Matilde|Brunet, Joan|Urioste, Miguel|Lazaro, Conxi|Moreno, Victor|Capella, Gabriel|Puente, Xose S|Valle, Laura
PMID: 27096942
Journal: Tumour Biol. 2017 Apr;39(4):1010428317697564.
Title: Methylation of the UNC5C gene and its protein expression in colorectal cancer.
Author: Wu, Jie|Wang, Guangchuan|He, Baojun|Chen, Xuejun|An, Yuzhi
PMID: 28378635
Journal: Asian Pac J Cancer Prev. 2018 May 26;19(5):1185-1188.
Title: Significant Pattern of Promoter Hypermethylation of UNC5C Gene in Colorectal Cancer and Its Implication in Late Stage Disease
Author: Guroo, Sartaj A|Malik, Ajaz A|Afroze, Dil|Ali, Shazia|Pandith, Arshad A|Yusuf, Adfar
PMID: 29801399