Primary Site >> Colorectal Cancer
Gene >> UNC5C
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Ref: Cloning of three mouse Unc5 genes and their expression patterns at mid-gestation. PMID: 12351186 |
Ref: Quantification of expression of netrins, slits and their receptors in human prostate tumors. PMID: 12471613 Ref: The netrin-1 receptors UNC5H are putative tumor suppressors controlling cell death commitment. PMID: 12655055 |
Ref: Analysis of Netrin 1 receptors during inner ear development. PMID: 17616930 Ref: Inactivation of the UNC5C Netrin-1 receptor is associated with tumor progression in colorectal malignancies. PMID: 17967459 Ref: Epigenetic and genetic alterations in Netrin-1 receptors UNC5C and DCC in human colon cancer. PMID: 18054557 |
Ref: NF-kappaB regulates netrin-1 expression and affects the conditional tumor suppressive activity of the netrin-1 receptors. PMID: 18692059 |
Ref: Netrin-1 increases proliferation and migration of renal proximal tubular epithelial cells via the UNC5B receptor. PMID: 19211685 Ref: Aberrant methylation of the netrin-1 receptor genes UNC5C and DCC detected in advanced colorectal cancer. PMID: 19242752 Ref: Aberrant methylation of the UNC5C gene is frequently detected in advanced colorectal cancer. PMID: 19331160 Ref: Segment-specific expression of netrin-1 receptors in normal and ischemic mouse kidney. PMID: 19372643 Ref: Changes in UNC5C gene methylation during human gastric carcinogenesis. PMID: 20032384 |
Ref: Netrin-1 regulates Th1/Th2/Th17 cytokine production and inflammation through UNC5B receptor and protects kidney against ischemia-reperfusion injury. PMID: 20693423 |
Ref: Variants in the netrin-1 receptor UNC5C prevent apoptosis and increase risk of familial colorectal cancer. PMID: 21893118 |
Ref: Netrin-1 simultaneously suppresses corneal inflammation and neovascularization. PMID: 22323486 Ref: Down syndrome cell adhesion molecule (DSCAM) associates with uncoordinated-5C (UNC5C) in netrin-1-mediated growth cone collapse. PMID: 22685302 |
Ref: Prenatal activation of maternal TLR3 receptors by viral-mimetic poly(I:C) modifies GluN2B expression in embryos and sonic hedgehog in offspring in the absence of kynurenine pathway activation. PMID: 23981041 |
Ref: Evaluation of the colorectal cancer risk conferred by rare UNC5C alleles. PMID: 24415873 |
Ref: Resilience to amphetamine in mouse models of netrin-1 haploinsufficiency: role of mesocortical dopamine. PMID: 26264903 |
Ref: Scarce evidence of the causal role of germline mutations in UNC5C in hereditary colorectal cancer and polyposis. PMID: 26852919 Ref: Erratum: Scarce evidence of the causal role of germline mutations in UNC5C in hereditary colorectal cancer and polyposis. PMID: 27096942 |
Ref: Methylation of the UNC5C gene and its protein expression in colorectal cancer. PMID: 28378635 |
Ref: Significant Pattern of Promoter Hypermethylation of UNC5C Gene in Colorectal Cancer and Its Implication in Late Stage Disease PMID: 29801399 |