Primary Site >> Liver Cancer

Gene >> UHRF1

Journal: Cancer Cell. 2014 Feb 10;25(2):196-209.
Title: UHRF1 overexpression drives DNA hypomethylation and hepatocellular carcinoma.
Author: Mudbhary, Raksha|Hoshida, Yujin|Chernyavskaya, Yelena|Jacob, Vinitha|Villanueva, Augusto|Fiel, M Isabel|Chen, Xintong|Kojima, Kensuke|Thung, Swan|Bronson, Roderick T|Lachenmayer, Anja|Revill, Kate|Alsinet, Clara|Sachidanandam, Ravi|Desai, Anal|SenBanerjee
PMID: 24486181
Journal: Int J Cancer. 2015 Jul 1;137(1):37-49.
Title: Negative modulation of the epigenetic regulator, UHRF1, by thyroid hormone receptors suppresses liver cancer cell growth.
Author: Wu, Sheng-Ming|Cheng, Wan-Li|Liao, Chia-Jung|Chi, Hsiang-Cheng|Lin, Yang-Hsiang|Tseng, Yi-Hsin|Tsai, Chung-Ying|Chen, Ching-Ying|Lin, Syuan-Ling|Chen, Wei-Jan|Yeh, Yung-Hsin|Huang, Chi-Ying F|Chen, Ming-Huang|Yeh, Yi-Chen|Lin, Kwang-Huei
PMID: 25430639
Journal: J Cancer. 2015 Jun 25;6(8):740-9.
Title: Methylation Profiling of Multiple Tumor Suppressor Genes in Hepatocellular Carcinoma and the Epigenetic Mechanism of 3OST2 Regulation.
Author: Chen, Haiyan|Zhang, Tingguo|Sheng, Yan|Zhang, Cheng|Peng, Yunfei|Wang, Xiao|Zhang, Cuijuan
PMID: 26185536
Journal: Oncol Rep. 2015 Oct;34(4):1708-16.
Title: The novel mTOR inhibitor Torin-2 induces autophagy and downregulates the expression of UHRF1 to suppress hepatocarcinoma cell growth.
Author: Wang, Congren|Wang, Xuejin|Su, Zijian|Fei, Hongjiang|Liu, Xiaoyu|Pan, Qunxiong
PMID: 26239364
Journal: Int J Clin Exp Pathol. 2015 Aug 1;8(8):9416-21. eCollection 2015.
Title: Elevated expression of UHRF1 predicts unfavorable prognosis for patients with hepatocellular carcinoma.
Author: Liang, Dong|Xue, Huanzhou|Yu, Yang|Lv, Feng|You, Wei|Zhang, Bin
PMID: 26464697
Journal: Mol Carcinog. 2016 Feb;55(2):209-19.
Title: The aberrant expression of MEG3 regulated by UHRF1 predicts the prognosis of hepatocellular carcinoma.
Author: Zhuo, Han|Tang, Junwei|Lin, Zhe|Jiang, Runqiu|Zhang, Xudong|Ji, Jie|Wang, Ping|Sun, Beicheng
PMID: 25641194
Journal: Mol Med Rep. 2016 Jan;13(1):315-20.
Title: UHRF1 promotes human osteosarcoma cell invasion by downregulating the expression of Ecadherin in an Rb1dependent manner.
Author: Liu, Wei|Qiao, Rui Hong|Wang, Dong Ming|Huang, Xiao Wei|Li, Bing|Wang, Dong
PMID: 26548607
Journal: Chem Res Toxicol. 2016 Oct 17;29(10):1773-1777.
Title: Trichloroethylene-Induced DNA Methylation Changes in Male F344 Rat Liver.
Author: Jiang, Yan|Chen, Jiahong|Yue, Cong|Zhang, Hang|Chen, Tao
PMID: 27618143
Journal: Oncotarget. 2016 Dec 13;7(50):83627-83640.
Title: Transcription factor LSF-DNMT1 complex dissociation by FQI1 leads to aberrant DNA methylation and gene expression.
Author: Chin, Hang Gyeong|Ponnaluri, V K Chaithanya|Zhang, Guoqiang|Esteve, Pierre-Olivier|Schaus, Scott E|Hansen, Ulla|Pradhan, Sriharsa
PMID: 27845898
Journal: Oncotarget. 2017 Feb 7;8(6):10510-10522.
Title: Elevated UHRF1 expression contributes to poor prognosis by promoting cell proliferation and metastasis in hepatocellular carcinoma.
Author: Liu, Xincheng|Ou, Huohui|Xiang, Leyang|Li, Xianghong|Huang, Yu|Yang, Dinghua
PMID: 28060737
Journal: Sci Rep. 2017 Jun 5;7(1):2798.
Title: Downregulation of UHRF1 increases tumor malignancy by activating the CXCR4/AKT-JNK/IL-6/Snail signaling axis in hepatocellular carcinoma cells.
Author: Kim, Ji-Hyun|Shim, Jae-Woong|Eum, Da-Young|Kim, Sung Dae|Choi, Si Ho|Yang, Kwangmo|Heo, Kyu|Park, Moon-Taek
PMID: 28584306
Journal: Clin Epigenetics. 2018 Mar 2;10:27.
Title: Overexpression of UHRF1 promotes silencing of tumor suppressor genes and predicts outcome in hepatoblastoma.
Author: Beck, Alexander|Trippel, Franziska|Wagner, Alexandra|Joppien, Saskia|Felle, Max|Vokuhl, Christian|Schwarzmayr, Thomas|Strom, Tim M|von Schweinitz, Dietrich|Langst, Gernot|Kappler, Roland
PMID: 29507645
Journal: Hepatology. 2018 Jul 16.
Title: Dual targeting of histone methyltransferase G9a and DNA-methyltransferase 1 for the treatment of experimental hepatocellular carcinoma.
Author: Barcena-Varela, Marina|Caruso, Stefano|Llerena, Susana|Alvarez-Sola, Gloria|Uriarte, Iker|Latasa, M Ujue|Urtasun, Raquel|Rebouissou, Sandra|Alvarez, Laura|Jimenez, Maddalen|Santamaria, Eva|Rodriguez-Ortigosa, Carlos|Mazza, Giuseppe|Rombouts, Krista|Jose-E
PMID: 30014490
Journal: Cell Death Dis. 2018 Sep 6;9(9):912.
Title: Differentiation therapy and the mechanisms that terminate cancer cell proliferation without harming normal cells.
Author: Enane, Francis O|Saunthararajah, Yogen|Korc, Murray
PMID: 30190481
Journal: Tissue Cell. 2018 Oct;54:65-71.
Title: ICBP90 mediates Notch signaling to facilitate human hepatocellular carcinoma growth.
Author: Fu, Haifeng|Xing, Feiyue|Lv, Yi|Zeng, Boning|You, Pengtao|Liu, Jing
PMID: 30309512