Primary Site >> Liver Cancer
Gene >> UHRF1
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Ref: UHRF1 overexpression drives DNA hypomethylation and hepatocellular carcinoma. PMID: 24486181 |
Ref: Negative modulation of the epigenetic regulator, UHRF1, by thyroid hormone receptors suppresses liver cancer cell growth. PMID: 25430639 Ref: Methylation Profiling of Multiple Tumor Suppressor Genes in Hepatocellular Carcinoma and the Epigenetic Mechanism of 3OST2 Regulation. PMID: 26185536 Ref: The novel mTOR inhibitor Torin-2 induces autophagy and downregulates the expression of UHRF1 to suppress hepatocarcinoma cell growth. PMID: 26239364 Ref: Elevated expression of UHRF1 predicts unfavorable prognosis for patients with hepatocellular carcinoma. PMID: 26464697 |
Ref: The aberrant expression of MEG3 regulated by UHRF1 predicts the prognosis of hepatocellular carcinoma. PMID: 25641194 Ref: UHRF1 promotes human osteosarcoma cell invasion by downregulating the expression of Ecadherin in an Rb1dependent manner. PMID: 26548607 Ref: Trichloroethylene-Induced DNA Methylation Changes in Male F344 Rat Liver. PMID: 27618143 Ref: Transcription factor LSF-DNMT1 complex dissociation by FQI1 leads to aberrant DNA methylation and gene expression. PMID: 27845898 |
Ref: Elevated UHRF1 expression contributes to poor prognosis by promoting cell proliferation and metastasis in hepatocellular carcinoma. PMID: 28060737 Ref: Downregulation of UHRF1 increases tumor malignancy by activating the CXCR4/AKT-JNK/IL-6/Snail signaling axis in hepatocellular carcinoma cells. PMID: 28584306 |
Ref: Overexpression of UHRF1 promotes silencing of tumor suppressor genes and predicts outcome in hepatoblastoma. PMID: 29507645 Ref: Dual targeting of histone methyltransferase G9a and DNA-methyltransferase 1 for the treatment of experimental hepatocellular carcinoma. PMID: 30014490 Ref: Differentiation therapy and the mechanisms that terminate cancer cell proliferation without harming normal cells. PMID: 30190481 Ref: ICBP90 mediates Notch signaling to facilitate human hepatocellular carcinoma growth. PMID: 30309512 |