Primary Site >> Liver Cancer

Gene >> UGT1A9

Journal: Cancer Res. 1997 Jul 15;57(14):2979-85.
Title: Differential down-regulation of the UDP-glucuronosyltransferase 1A locus is an early event in human liver and biliary cancer.
Author: Strassburg, C P|Manns, M P|Tukey, R H
PMID: 9230212
Journal: Gastroenterology. 2001 Nov;121(5):1136-44.
Title: Genetic link of hepatocellular carcinoma with polymorphisms of the UDP-glucuronosyltransferase UGT1A7 gene.
Author: Vogel, A|Kneip, S|Barut, A|Ehmer, U|Tukey, R H|Manns, M P|Strassburg, C P
PMID: 11677206
Journal: Hepatology. 2004 Apr;39(4):970-7.
Title: Variation of hepatic glucuronidation: Novel functional polymorphisms of the UDP-glucuronosyltransferase UGT1A4.
Author: Ehmer, Ursula|Vogel, Arndt|Schutte, Jan Karl|Krone, Britta|Manns, Michael P|Strassburg, Christian P
PMID: 15057901
Journal: Gastroenterology. 2010 Nov;139(5):1699-710, 1710.e1-2.
Title: Coffee induces expression of glucuronosyltransferases by the aryl hydrocarbon receptor and Nrf2 in liver and stomach.
Author: Kalthoff, Sandra|Ehmer, Ursula|Freiberg, Nicole|Manns, Michael P|Strassburg, Christian P
PMID: 20600030
Journal: Invest New Drugs. 2011 Dec;29(6):1511-4.
Title: Pharmacokinetic interaction involving sorafenib and the calcium-channel blocker felodipine in a patient with hepatocellular carcinoma.
Author: Gomo, Charline|Coriat, Romain|Faivre, Lionel|Mir, Olivier|Ropert, Stanislas|Billemont, Bertrand|Dauphin, Alain|Tod, Michel|Goldwasser, Francois|Blanchet, Benoit
PMID: 20706860
Journal: Br J Clin Pharmacol. 2011 Aug;72(2):294-305.
Title: Population pharmacokinetic analysis of sorafenib in patients with solid tumours.
Author: Jain, Lokesh|Woo, Sukyung|Gardner, Erin R|Dahut, William L|Kohn, Elise C|Kummar, Shivaani|Mould, Diane R|Giaccone, Giuseppe|Yarchoan, Robert|Venitz, Jurgen|Figg, William D
PMID: 21392074
Journal: Transplant Proc. 2011 Sep;43(7):2800-5.
Title: Using sorafenib for recurrent hepatocellular carcinoma after liver transplantation--interactions between calcineurin inhibitor: two case reports.
Author: Takahara, T|Nitta, H|Hasegawa, Y|Itou, N|Takahashi, M|Wakabayashi, G
PMID: 21911167
Journal: Chemosphere. 2012 Oct;89(5):526-9.
Title: Effect of aflatoxin B1 on UDP-glucuronosyltransferase mRNA expression in HepG2 cells.
Author: Hanioka, Nobumitsu|Nonaka, Yuko|Saito, Keita|Negishi, Tomoe|Okamoto, Keinosuke|Kataoka, Hiroyuki|Narimatsu, Shizuo
PMID: 22749127
Journal: Cancer. 2013 Jan 1;119(1):136-42.
Title: Genetic predisposition of hand-foot skin reaction after sorafenib therapy in patients with hepatocellular carcinoma.
Author: Lee, Joo Ho|Chung, Young-Hwa|Kim, Jeong A|Shim, Ju Hyun|Lee, Danbi|Lee, Han Chu|Shin, Eun-Soon|Yoon, Jung Hwan|Kim, Byung Ik|Bae, Si Hyun|Koh, Kwang Cheol|Park, Neung-Hwa
PMID: 22736425
Journal: Cancer Chemother Pharmacol. 2013 Jul;72(1):269-72.
Title: Pharmacokinetic interaction between sorafenib and prednisolone in a patient with hepatocellular carcinoma.
Author: Noda, Satoshi|Shioya, Makoto|Hira, Daiki|Fujiyama, Yoshihide|Morita, Shin-ya|Terada, Tomohiro
PMID: 23673446
Journal: PLoS One. 2014 May 5;9(5):e96664.
Title: Sorafenib metabolism is significantly altered in the liver tumor tissue of hepatocellular carcinoma patient.
Author: Ye, Ling|Yang, Xiaoshan|Guo, Enshuang|Chen, Weiying|Lu, Linlin|Wang, Ying|Peng, Xiaojuan|Yan, Tongmeng|Zhou, Fuyan|Liu, Zhongqiu
PMID: 24797816
Journal: Pharm Res. 2015 Mar;32(3):1141-57.
Title: Significantly decreased and more variable expression of major CYPs and UGTs in liver microsomes prepared from HBV-positive human hepatocellular carcinoma and matched pericarcinomatous tissues determined using an isotope label-free UPLC-MS/MS method.
Author: Yan, Tongmeng|Gao, Song|Peng, Xiaojuan|Shi, Jian|Xie, Cong|Li, Qiang|Lu, Linlin|Wang, Ying|Zhou, Fuyuan|Liu, Zhongqiu|Hu, Ming
PMID: 25288013
Journal: PLoS One. 2015 May 26;10(5):e0127524.
Title: Drug-Metabolizing Activity, Protein and Gene Expression of UDP-Glucuronosyltransferases Are Significantly Altered in Hepatocellular Carcinoma Patients.
Author: Lu, Linlin|Zhou, Juan|Shi, Jian|Peng, Xiao-juan|Qi, Xiao-xiao|Wang, Ying|Li, Fang-Yuan|Zhou, Fu-Yuan|Liu, Liang|Liu, Zhong-Qiu
PMID: 26010150
Journal: Pharmacogenomics. 2016 Sep;17(14):1483-90.
Title: Polymorphisms in SLCO1B1 and UGT1A1 are associated with sorafenib-induced toxicity.
Author: Bins, Sander|Lenting, Anne|El Bouazzaoui, Samira|van Doorn, Leni|Oomen-de Hoop, Esther|Eskens, Ferry Alm|van Schaik, Ron Hn|Mathijssen, Ron Hj
PMID: 27533851
Journal: Liver Int. 2017 Sep;37(9):1345-1353.
Title: UGT1A polymorphisms as genetic biomarkers for hepatocellular carcinoma risk in Caucasian population.
Author: De Mattia, Elena|Cecchin, Erika|Polesel, Jerry|Lupo, Francesco|Tiribelli, Claudio|Crovatto, Marina|Buonadonna, Angela|Toffoli, Giuseppe
PMID: 28294511