Primary Site >> Liver Cancer
Gene >> UGT1A9
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Ref: Differential down-regulation of the UDP-glucuronosyltransferase 1A locus is an early event in human liver and biliary cancer. PMID: 9230212 |
Ref: Genetic link of hepatocellular carcinoma with polymorphisms of the UDP-glucuronosyltransferase UGT1A7 gene. PMID: 11677206 |
Ref: Variation of hepatic glucuronidation: Novel functional polymorphisms of the UDP-glucuronosyltransferase UGT1A4. PMID: 15057901 |
Ref: Coffee induces expression of glucuronosyltransferases by the aryl hydrocarbon receptor and Nrf2 in liver and stomach. PMID: 20600030 |
Ref: Pharmacokinetic interaction involving sorafenib and the calcium-channel blocker felodipine in a patient with hepatocellular carcinoma. PMID: 20706860 Ref: Population pharmacokinetic analysis of sorafenib in patients with solid tumours. PMID: 21392074 Ref: Using sorafenib for recurrent hepatocellular carcinoma after liver transplantation--interactions between calcineurin inhibitor: two case reports. PMID: 21911167 |
Ref: Effect of aflatoxin B1 on UDP-glucuronosyltransferase mRNA expression in HepG2 cells. PMID: 22749127 |
Ref: Genetic predisposition of hand-foot skin reaction after sorafenib therapy in patients with hepatocellular carcinoma. PMID: 22736425 Ref: Pharmacokinetic interaction between sorafenib and prednisolone in a patient with hepatocellular carcinoma. PMID: 23673446 |
Ref: Sorafenib metabolism is significantly altered in the liver tumor tissue of hepatocellular carcinoma patient. PMID: 24797816 |
Ref: Significantly decreased and more variable expression of major CYPs and UGTs in liver microsomes prepared from HBV-positive human hepatocellular carcinoma and matched pericarcinomatous tissues determined using an isotope label-free UPLC-MS/MS method. PMID: 25288013 Ref: Drug-Metabolizing Activity, Protein and Gene Expression of UDP-Glucuronosyltransferases Are Significantly Altered in Hepatocellular Carcinoma Patients. PMID: 26010150 |
Ref: Polymorphisms in SLCO1B1 and UGT1A1 are associated with sorafenib-induced toxicity. PMID: 27533851 |
Ref: UGT1A polymorphisms as genetic biomarkers for hepatocellular carcinoma risk in Caucasian population. PMID: 28294511 |