Primary Site >> Colorectal Cancer
Gene >> UGT1A6
| 1. | |||||||||||
| Journal: | Arch Biochem Biophys. 1996 Nov 1;335(1):205-10. | ||||||||||
| Title: | Tissue-specific 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible expression of human UDP-glucuronosyltransferase UGT1A6. | ||||||||||
| Author: | Munzel, P A|Bookjans, G|Mehner, G|Lehmkoster, T|Bock, K W | ||||||||||
| PMID: | 8914852 | ||||||||||
| 2. | |||||||||||
| Journal: | Arch Biochem Biophys. 1998 Feb 1;350(1):72-8. | ||||||||||
| Title: | Aryl hydrocarbon receptor-inducible or constitutive expression of human UDP glucuronosyltransferase UGT1A6. | ||||||||||
| Author: | Munzel, P A|Lehmkoster, T|Bruck, M|Ritter, J K|Bock, K W | ||||||||||
| PMID: | 9466822 | ||||||||||
| 3. | |||||||||||
| Journal: | Adv Enzyme Regul. 1998;38:207-22. | ||||||||||
| Title: | AH receptor-controlled transcriptional regulation and function of rat and human UDP-glucuronosyltransferase isoforms. | ||||||||||
| Author: | Bock, K W|Gschaidmeier, H|Heel, H|Lehmkoster, T|Munzel, P A|Raschko, F|Bock-Hennig, B | ||||||||||
| PMID: | 9762354 | ||||||||||
| 4. | |||||||||||
| Journal: | Drug Metab Dispos. 1999 May;27(5):569-73. | ||||||||||
| Title: | Induction of human UDP glucuronosyltransferases (UGT1A6, UGT1A9, and UGT2B7) by t-butylhydroquinone and 2,3,7,8-tetrachlorodibenzo-p-dioxin in Caco-2 cells. | ||||||||||
| Author: | Munzel, P A|Schmohl, S|Heel, H|Kalberer, K|Bock-Hennig, B S|Bock, K W | ||||||||||
| PMID: | 10220484 | ||||||||||
| 5. | |||||||||||
| Journal: | Ther Drug Monit. 2000 Feb;22(1):10-3. | ||||||||||
| Title: | Identification of uridine diphosphate glucuronosyltransferases involved in the metabolism and clearance of mycophenolic acid. | ||||||||||
| Author: | Mackenzie, P I | ||||||||||
| PMID: | 10688250 | ||||||||||
| 6. | |||||||||||
| Journal: | Life Sci. 2000;67(2):185-96. | ||||||||||
| Title: | Nonsteroidal anti-inflammatory drugs and phenols glucuronidation in Caco-2 cells: identification of the UDP-glucuronosyltransferases UGT1A6, 1A3 and 2B7. | ||||||||||
| Author: | Sabolovic, N|Magdalou, J|Netter, P|Abid, A | ||||||||||
| PMID: | 10901286 | ||||||||||
| 7. | |||||||||||
| Journal: | Cancer Res. 2001 May 1;61(9):3566-9. | ||||||||||
| Title: | CYP2C9 and UGT1A6 genotypes modulate the protective effect of aspirin on colon adenoma risk. | ||||||||||
| Author: | Bigler, J|Whitton, J|Lampe, J W|Fosdick, L|Bostick, R M|Potter, J D | ||||||||||
| PMID: | 11325819 | ||||||||||
| 8. | |||||||||||
| Journal: | Biochem Pharmacol. 2002 May 1;63(9):1683-90. | ||||||||||
| Title: | Tissue-specific regulation of canine intestinal and hepatic phenol and morphine UDP-glucuronosyltransferases by beta-naphthoflavone in comparison with humans. | ||||||||||
| Author: | Bock, Karl Walter|Bock-Hennig, Barbara S|Munzel, Peter A|Brandenburg, Jens O|Kohle, Christoph T|Soars, Matthew G|Riley, Rob J|Burchell, Brian|von Richter, Oliver|Eichelbaum, Michel F|Swedmark, Stellan|Orzechowski, Achim | ||||||||||
| PMID: | 12007571 | ||||||||||
| 9. | |||||||||||
| Journal: | Carcinogenesis. 2004 Dec;25(12):2407-15. Epub 2004 Aug 19. | ||||||||||
| Title: | Genetic polymorphisms in UDP-glucuronosyltransferases and glutathione S-transferases and colorectal cancer risk. | ||||||||||
| Author: | van der Logt, E M J|Bergevoet, S M|Roelofs, H M J|van Hooijdonk, Z|te Morsche, R H M|Wobbes, T|de Kok, J B|Nagengast, F M|Peters, W H M | ||||||||||
| PMID: | 15319294 | ||||||||||
| 10. | |||||||||||
| Journal: | Biol Pharm Bull. 2005 Feb;28(2):271-4. | ||||||||||
| Title: | The effects of coffee on conjugation reactions in human colon carcinoma cells. | ||||||||||
| Author: | Okamura, Shigeaki|Suzuki, Keiko|Yanase, Masayo|Koizumi, Masumi|Tamura, Hiro-omi | ||||||||||
| PMID: | 15684482 | ||||||||||
| 11. | |||||||||||
| Journal: | Clin Cancer Res. 2005 Feb 1;11(3):1226-36. | ||||||||||
| Title: | UGT1A7 and UGT1A9 polymorphisms predict response and toxicity in colorectal cancer patients treated with capecitabine/irinotecan. | ||||||||||
| Author: | Carlini, Leslie E|Meropol, Neal J|Bever, John|Andria, Michael L|Hill, Todd|Gold, Philip|Rogatko, Andre|Wang, Hao|Blanchard, Rebecca L | ||||||||||
| PMID: | 15709193 | ||||||||||
| 12. | |||||||||||
| Journal: | Pharmacogenet Genomics. 2005 Oct;15(10):713-21. | ||||||||||
| Title: | No evidence that polymorphisms in CYP2C8, CYP2C9, UGT1A6, PPARdelta and PPARgamma act as modifiers of the protective effect of regular NSAID use on the risk of colorectal carcinoma. | ||||||||||
| Author: | McGreavey, Louise E|Turner, Faye|Smith, Gillian|Boylan, Katherine|Timothy Bishop, D|Forman, David|Roland Wolf, C|Barrett, Jennifer H | ||||||||||
| PMID: | 16141797 | ||||||||||
| 13. | |||||||||||
| Journal: | Biol Pharm Bull. 2006 Jul;29(7):1476-9. | ||||||||||
| Title: | Turmeric and curcumin modulate the conjugation of 1-naphthol in Caco-2 cells. | ||||||||||
| Author: | Naganuma, Megumi|Saruwatari, Ayako|Okamura, Shigeaki|Tamura, Hiroomi | ||||||||||
| PMID: | 16819192 | ||||||||||
| 14. | |||||||||||
| Journal: | Clin Gastroenterol Hepatol. 2006 Jul;4(7):894-901. Epub 2006 Jun 22. | ||||||||||
| Title: | Interactions between CYP2C9 and UGT1A6 polymorphisms and nonsteroidal anti-inflammatory drugs in colorectal cancer prevention. | ||||||||||
| Author: | Samowitz, Wade S|Wolff, Roger K|Curtin, Karen|Sweeney, Carol|Ma, Khe-Ni|Andersen, Kristen|Levin, Theodore R|Slattery, Martha L | ||||||||||
| PMID: | 16797247 | ||||||||||
| 15. | |||||||||||
| Journal: | Drug Metab Dispos. 2008 Nov;36(11):2331-6. | ||||||||||
| Title: | The expression of most UDP-glucuronosyltransferases (UGTs) is increased significantly during Caco-2 cell differentiation, whereas UGT1A6 is highly expressed also in undifferentiated cells. | ||||||||||
| Author: | Siissalo, Sanna|Zhang, Hongbo|Stilgenbauer, Eric|Kaukonen, Ann Marie|Hirvonen, Jouni|Finel, Moshe | ||||||||||
| PMID: | 18694909 | ||||||||||
| 16. | |||||||||||
| Journal: | World J Gastroenterol. 2009 May 14;15(18):2240-4. | ||||||||||
| Title: | No association between cyclooxygenase-2 and uridine diphosphate glucuronosyltransferase 1A6 genetic polymorphisms and colon cancer risk. | ||||||||||
| Author: | Thompson, Cheryl-L|Plummer, Sarah-J|Merkulova, Alona|Cheng, Iona|Tucker, Thomas-C|Casey, Graham|Li, Li | ||||||||||
| PMID: | 19437564 | ||||||||||
| 17. | |||||||||||
| Journal: | Innate Immun. 2010 Oct;16(5):302-9. | ||||||||||
| Title: | Expression of UDP-glucuronosyltransferase 1A6 isoform in Caco-2 cells stimulated with lipopolysaccharide. | ||||||||||
| Author: | Panaro, Maria Antonietta|Cavallo, Pasqua|Acquafredda, Angela|Cianciulli, Antonia|Calvello, Rosa|Mitolo, Vincenzo | ||||||||||
| PMID: | 19710100 | ||||||||||
| 18. | |||||||||||
| Journal: | Drug Metab Rev. 2010 Feb;42(1):6-13. | ||||||||||
| Title: | UDP-glucuronosyltransferases (UGTs): from purification of Ah-receptor-inducible UGT1A6 to coordinate regulation of subsets of CYPs, UGTs, and ABC transporters by nuclear receptors. | ||||||||||
| Author: | Bock, Karl W|Bock-Hennig, Barbara S | ||||||||||
| PMID: | 19831498 | ||||||||||
| 19. | |||||||||||
| Journal: | Asian Pac J Cancer Prev. 2012;13(5):2311-4. | ||||||||||
| Title: | Association between polymorphisms in UDP-glucuronosyltransferase 1A6 and 1A7 and colorectal cancer risk. | ||||||||||
| Author: | Osawa, Kayo|Nakarai, Chiaki|Akiyama, Minami|Hashimoto, Ryuta|Tsutou, Akimitsu|Takahashi, Juro|Takaoka, Yuko|Kawamura, Shiro|Shimada, Etsuji|Tanaka, Kenichi|Kozuka, Masaya|Yamamoto, Masahiro|Kido, Yoshiaki | ||||||||||
| PMID: | 22901212 | ||||||||||
| 20. | |||||||||||
| Journal: | Genes Chromosomes Cancer. 2014 Jul;53(7):568-78. | ||||||||||
| Title: | Genetic variation in UGT genes modify the associations of NSAIDs with risk of colorectal cancer: colon cancer family registry. | ||||||||||
| Author: | Scherer, Dominique|Koepl, Lisel M|Poole, Elizabeth M|Balavarca, Yesilda|Xiao, Liren|Baron, John A|Hsu, Li|Coghill, Anna E|Campbell, Peter T|Kleinstein, Sarah E|Figueiredo, Jane C|Lampe, Johanna W|Buck, Katharina|Potter, John D|Kulmacz, Richard J|Jenkins, | ||||||||||
| PMID: | 24677636 | ||||||||||
| 21. | |||||||||||
| Journal: | BMC Med Genet. 2015 Mar 24;16:18. | ||||||||||
| Title: | Tissue-specific patterns of gene expression in the epithelium and stroma of normal colon in healthy individuals in an aspirin intervention trial. | ||||||||||
| Author: | Thomas, Sushma S|Makar, Karen W|Li, Lin|Zheng, Yingye|Yang, Peiying|Levy, Lisa|Rudolph, Rebecca Yvonne|Lampe, Paul D|Yan, Min|Markowitz, Sanford D|Bigler, Jeannette|Lampe, Johanna W|Potter, John D | ||||||||||
| PMID: | 25927723 | ||||||||||
| 22. | |||||||||||
| Journal: | Int J Clin Exp Pathol. 2015 Mar 1;8(3):2888-98. eCollection 2015. | ||||||||||
| Title: | Biomarkers of erlotinib response in non-small cell lung cancer tumors that do not harbor the more common epidermal growth factor receptor mutations. | ||||||||||
| Author: | Lopez-Ayllon, Blanca D|de Castro-Carpeno, Javier|Rodriguez, Carlos|Pernia, Olga|Ibanez de Caceres, Inmaculada|Belda-Iniesta, Cristobal|Perona, Rosario|Sastre, Leandro | ||||||||||
| PMID: | 26045797 | ||||||||||
| 23. | |||||||||||
| Journal: | Genom Data. 2015 Sep 1;6:154-8. | ||||||||||
| Title: | Tissue-specific patterns of gene expression in the epithelium and stroma of normal colon in healthy individuals in an aspirin intervention trial. | ||||||||||
| Author: | Thomas, Sushma S|Makar, Karen W|Li, Lin|Zheng, Yingye|Yang, Peiying|Levy, Lisa|Rudolph, Rebecca Y|Lampe, Paul D|Yan, Min|Markowitz, Sanford D|Bigler, Jeannette|Lampe, Johanna W|Potter, John D | ||||||||||
| PMID: | 26697360 | ||||||||||
| 24. | |||||||||||
| Journal: | Br J Cancer. 2017 Sep 26;117(7):965-973. | ||||||||||
| Title: | Pharmacogenetic determinants of outcomes on triplet hepatic artery infusion and intravenous cetuximab for liver metastases from colorectal cancer (European trial OPTILIV, NCT00852228). | ||||||||||
| Author: | Levi, Francis|Karaboue, Abdoulaye|Saffroy, Raphael|Desterke, Christophe|Boige, Valerie|Smith, Denis|Hebbar, Mohamed|Innominato, Pasquale|Taieb, Julien|Carvalho, Carlos|Guimbaud, Rosine|Focan, Christian|Bouchahda, Mohamed|Adam, Rene|Ducreux, Michel|Milano, | ||||||||||
| PMID: | 28817838 | ||||||||||
| 25. | |||||||||||
| Journal: | BMC Cancer. 2017 Dec 28;17(1):901. | ||||||||||
| Title: | Common variants in glucuronidation enzymes and membrane transporters as potential risk factors for colorectal cancer: a case control study. | ||||||||||
| Author: | Falkowski, Sabrina|Woillard, Jean-Baptiste|Postil, Deborah|Tubiana-Mathieu, Nicole|Terrebonne, Eric|Pariente, Antoine|Smith, Denis|Guimbaud, Rosine|Thalamas, Claire|Rouguieg-Malki, Koukeb|Marquet, Pierre|Picard, Nicolas | ||||||||||
| PMID: | 29282011 | ||||||||||
| 26. | |||||||||||
| Journal: | PLoS One. 2018 Feb 9;13(2):e0192223. | ||||||||||
| Title: | Interaction between polymorphisms in aspirin metabolic pathways, regular aspirin use and colorectal cancer risk: A case-control study in unselected white European populations. | ||||||||||
| Author: | Sheth, Harsh|Northwood, Emma|Ulrich, Cornelia M|Scherer, Dominique|Elliott, Faye|Barrett, Jennifer H|Forman, David|Wolf, C Roland|Smith, Gillian|Jackson, Michael S|Santibanez-Koref, Mauro|Haile, Robert|Casey, Graham|Jenkins, Mark|Win, Aung Ko|Hopper, John | ||||||||||
| PMID: | 29425227 | ||||||||||