Primary Site >> Liver Cancer

Gene >> UGT1A4

Journal: Cancer Res. 1997 Jul 15;57(14):2979-85.
Title: Differential down-regulation of the UDP-glucuronosyltransferase 1A locus is an early event in human liver and biliary cancer.
Author: Strassburg, C P|Manns, M P|Tukey, R H
PMID: 9230212
Journal: Hepatology. 2004 Apr;39(4):970-7.
Title: Variation of hepatic glucuronidation: Novel functional polymorphisms of the UDP-glucuronosyltransferase UGT1A4.
Author: Ehmer, Ursula|Vogel, Arndt|Schutte, Jan Karl|Krone, Britta|Manns, Michael P|Strassburg, Christian P
PMID: 15057901
Journal: Gastroenterology. 2010 Nov;139(5):1699-710, 1710.e1-2.
Title: Coffee induces expression of glucuronosyltransferases by the aryl hydrocarbon receptor and Nrf2 in liver and stomach.
Author: Kalthoff, Sandra|Ehmer, Ursula|Freiberg, Nicole|Manns, Michael P|Strassburg, Christian P
PMID: 20600030
Journal: Chemosphere. 2012 Oct;89(5):526-9.
Title: Effect of aflatoxin B1 on UDP-glucuronosyltransferase mRNA expression in HepG2 cells.
Author: Hanioka, Nobumitsu|Nonaka, Yuko|Saito, Keita|Negishi, Tomoe|Okamoto, Keinosuke|Kataoka, Hiroyuki|Narimatsu, Shizuo
PMID: 22749127
Journal: Front Endocrinol (Lausanne). 2013 Jun 26;4:75.
Title: Implication of Human UGT2B7, 2B15, and 2B17 in 19-Norandrosterone Metabolism.
Author: Strahm, Emmanuel|Sjoberg, Ulf|Garle, Mats|Rane, Anders|Ekstrom, Lena
PMID: 23805127
Journal: Pharm Res. 2015 Mar;32(3):1141-57.
Title: Significantly decreased and more variable expression of major CYPs and UGTs in liver microsomes prepared from HBV-positive human hepatocellular carcinoma and matched pericarcinomatous tissues determined using an isotope label-free UPLC-MS/MS method.
Author: Yan, Tongmeng|Gao, Song|Peng, Xiaojuan|Shi, Jian|Xie, Cong|Li, Qiang|Lu, Linlin|Wang, Ying|Zhou, Fuyuan|Liu, Zhongqiu|Hu, Ming
PMID: 25288013
Journal: PLoS One. 2015 May 26;10(5):e0127524.
Title: Drug-Metabolizing Activity, Protein and Gene Expression of UDP-Glucuronosyltransferases Are Significantly Altered in Hepatocellular Carcinoma Patients.
Author: Lu, Linlin|Zhou, Juan|Shi, Jian|Peng, Xiao-juan|Qi, Xiao-xiao|Wang, Ying|Li, Fang-Yuan|Zhou, Fu-Yuan|Liu, Liang|Liu, Zhong-Qiu
PMID: 26010150