Primary Site >> Liver Cancer

Gene >> UGT1A4

  • 1997
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  • 2015
Ref: Differential down-regulation of the UDP-glucuronosyltransferase 1A locus is an early event in human liver and biliary cancer.
PMID: 9230212
Ref: Variation of hepatic glucuronidation: Novel functional polymorphisms of the UDP-glucuronosyltransferase UGT1A4.
PMID: 15057901
Ref: Coffee induces expression of glucuronosyltransferases by the aryl hydrocarbon receptor and Nrf2 in liver and stomach.
PMID: 20600030
Ref: Effect of aflatoxin B1 on UDP-glucuronosyltransferase mRNA expression in HepG2 cells.
PMID: 22749127
Ref: Implication of Human UGT2B7, 2B15, and 2B17 in 19-Norandrosterone Metabolism.
PMID: 23805127
Ref: Significantly decreased and more variable expression of major CYPs and UGTs in liver microsomes prepared from HBV-positive human hepatocellular carcinoma and matched pericarcinomatous tissues determined using an isotope label-free UPLC-MS/MS method.
PMID: 25288013
Ref: Drug-Metabolizing Activity, Protein and Gene Expression of UDP-Glucuronosyltransferases Are Significantly Altered in Hepatocellular Carcinoma Patients.
PMID: 26010150