Primary Site >> Liver Cancer
Gene >> UGT1A1
| 1. | |||||||||||
| Journal: | Cancer Res. 1997 Jul 15;57(14):2979-85. | ||||||||||
| Title: | Differential down-regulation of the UDP-glucuronosyltransferase 1A locus is an early event in human liver and biliary cancer. | ||||||||||
| Author: | Strassburg, C P|Manns, M P|Tukey, R H | ||||||||||
| PMID: | 9230212 | ||||||||||
| 2. | |||||||||||
| Journal: | Cancer Res. 2000 Feb 15;60(4):950-6. | ||||||||||
| Title: | Genetic polymorphisms in uridine diphospho-glucuronosyltransferase 1A1 and association with breast cancer among African Americans. | ||||||||||
| Author: | Guillemette, C|Millikan, R C|Newman, B|Housman, D E | ||||||||||
| PMID: | 10706110 | ||||||||||
| 3. | |||||||||||
| Journal: | Hepatology. 2004 Apr;39(4):970-7. | ||||||||||
| Title: | Variation of hepatic glucuronidation: Novel functional polymorphisms of the UDP-glucuronosyltransferase UGT1A4. | ||||||||||
| Author: | Ehmer, Ursula|Vogel, Arndt|Schutte, Jan Karl|Krone, Britta|Manns, Michael P|Strassburg, Christian P | ||||||||||
| PMID: | 15057901 | ||||||||||
| 4. | |||||||||||
| Journal: | World J Gastroenterol. 2005 Feb 14;11(6):797-802. | ||||||||||
| Title: | Polymorphisms of uridine-diphosphoglucuronosyltransferase 1A7 gene in Taiwan Chinese. | ||||||||||
| Author: | Huang, May-Jen|Yang, Sien-Sing|Lin, Min-Shung|Huang, Ching-Shan | ||||||||||
| PMID: | 15682470 | ||||||||||
| 5. | |||||||||||
| Journal: | Drug Metab Dispos. 2006 Jan;34(1):75-83. | ||||||||||
| Title: | Expression of cytochromes P450, conjugating enzymes and nuclear receptors in human hepatoma HepaRG cells. | ||||||||||
| Author: | Aninat, Caroline|Piton, Amelie|Glaise, Denise|Le Charpentier, Typhen|Langouet, Sophie|Morel, Fabrice|Guguen-Guillouzo, Christiane|Guillouzo, Andre | ||||||||||
| PMID: | 16204462 | ||||||||||
| 6. | |||||||||||
| Journal: | Basic Clin Pharmacol Toxicol. 2008 Apr;102(4):399-407. | ||||||||||
| Title: | Chemosensitivity determinants of irinotecan hydrochloride in hepatocellular carcinoma cell lines. | ||||||||||
| Author: | Takahata, Takenori|Ookawa, Keizou|Suto, Koji|Tanaka, Masanori|Yano, Hirohisa|Nakashima, Osamu|Kojiro, Masamichi|Tamura, Yoshihiro|Tateishi, Tomonori|Sakata, Yuh|Fukuda, Shinsaku | ||||||||||
| PMID: | 18248513 | ||||||||||
| 7. | |||||||||||
| Journal: | Arch Toxicol. 2008 Jul;82(7):415-33. | ||||||||||
| Title: | Family 1 uridine-5'-diphosphate glucuronosyltransferases (UGT1A): from Gilbert's syndrome to genetic organization and variability. | ||||||||||
| Author: | Strassburg, Christian P|Lankisch, Tim O|Manns, Michael P|Ehmer, Ursula | ||||||||||
| PMID: | 18491077 | ||||||||||
| 8. | |||||||||||
| Journal: | Biomed Mater. 2008 Sep;3(3):034120. | ||||||||||
| Title: | The three-dimensional cultivation of the carcinoma cell line HepG2 in a perfused chip system leads to a more differentiated phenotype of the cells compared to monolayer culture. | ||||||||||
| Author: | Altmann, B|Giselbrecht, S|Weibezahn, K-F|Welle, A|Gottwald, E | ||||||||||
| PMID: | 18765895 | ||||||||||
| 9. | |||||||||||
| Journal: | Gastroenterology. 2010 Nov;139(5):1699-710, 1710.e1-2. | ||||||||||
| Title: | Coffee induces expression of glucuronosyltransferases by the aryl hydrocarbon receptor and Nrf2 in liver and stomach. | ||||||||||
| Author: | Kalthoff, Sandra|Ehmer, Ursula|Freiberg, Nicole|Manns, Michael P|Strassburg, Christian P | ||||||||||
| PMID: | 20600030 | ||||||||||
| 10. | |||||||||||
| Journal: | J Pathol. 2011 Feb;223(3):425-35. | ||||||||||
| Title: | Immunohistochemical expression of conjugating UGT1A-derived isoforms in normal and tumoral drug-metabolizing tissues in humans. | ||||||||||
| Author: | Bellemare, Judith|Rouleau, Melanie|Harvey, Mario|Popa, Ion|Pelletier, Georges|Tetu, Bernard|Guillemette, Chantal | ||||||||||
| PMID: | 21171088 | ||||||||||
| 11. | |||||||||||
| Journal: | Biopharm Drug Dispos. 2011 Jul;32(5):289-300. | ||||||||||
| Title: | Pharmacodynamics of dietary phytochemical indoles I3C and DIM: Induction of Nrf2-mediated phase II drug metabolizing and antioxidant genes and synergism with isothiocyanates. | ||||||||||
| Author: | Saw, Constance Lay-Lay|Cintron, Melvili|Wu, Tien-Yuan|Guo, Yue|Huang, Ying|Jeong, Woo-Sik|Kong, Ah-Ng Tony | ||||||||||
| PMID: | 21656528 | ||||||||||
| 12. | |||||||||||
| Journal: | Gastrointest Cancer Res. 2011 Mar;4(2):40-4. | ||||||||||
| Title: | Safety and Efficacy of Sorafenib in Patients with Hepatocellular Carcinoma (HCC) and Child-Pugh A versus B Cirrhosis. | ||||||||||
| Author: | Abou-Alfa, Ghassan K|Amadori, Dino|Santoro, Armando|Figer, Arie|De Greve, Jacques|Lathia, Chetan|Voliotis, Dimitris|Anderson, Sibyl|Moscovici, Marius|Ricci, Sergio | ||||||||||
| PMID: | 21673874 | ||||||||||
| 13. | |||||||||||
| Journal: | Drug Metab Pharmacokinet. 2012;27(5):478-85. Epub 2012 Mar 6. | ||||||||||
| Title: | Increased expression of drug-metabolizing enzymes in human hepatocarcinoma FLC-4 cells cultured on micro-space cell culture plates. | ||||||||||
| Author: | Kobayashi, Kaoru|Yoshida, Akane|Ejiri, Yoko|Takagi, Sachiko|Mimura, Hanaka|Hosoda, Masaya|Matsuura, Tomokazu|Chiba, Kan | ||||||||||
| PMID: | 22447115 | ||||||||||
| 14. | |||||||||||
| Journal: | Chemosphere. 2012 Oct;89(5):526-9. | ||||||||||
| Title: | Effect of aflatoxin B1 on UDP-glucuronosyltransferase mRNA expression in HepG2 cells. | ||||||||||
| Author: | Hanioka, Nobumitsu|Nonaka, Yuko|Saito, Keita|Negishi, Tomoe|Okamoto, Keinosuke|Kataoka, Hiroyuki|Narimatsu, Shizuo | ||||||||||
| PMID: | 22749127 | ||||||||||
| 15. | |||||||||||
| Journal: | PLoS One. 2013;8(1):e54522. | ||||||||||
| Title: | Glucuronidation by UGT1A1 is the dominant pathway of the metabolic disposition of belinostat in liver cancer patients. | ||||||||||
| Author: | Wang, Ling-Zhi|Ramirez, Jacqueline|Yeo, Winnie|Chan, Mei-Yi Michelle|Thuya, Win-Lwin|Lau, Jie-Ying Amelia|Wan, Seow-Ching|Wong, Andrea Li-Ann|Zee, Ying-Kiat|Lim, Robert|Lee, Soo-Chin|Ho, Paul C|Lee, How-Sung|Chan, Anthony|Ansher, Sherry|Ratain, Mark J|Goh | ||||||||||
| PMID: | 23382909 | ||||||||||
| 16. | |||||||||||
| Journal: | Anticancer Res. 2013 Apr;33(4):1603-7. | ||||||||||
| Title: | High-dose FOLFIRI, surgery, and radiofrequency ablation for patients with unresectable liver metastases from colorectal cancer. | ||||||||||
| Author: | Hebbar, Mohamed|Truant, Stephanie|Desauw, Christophe|Sergent-Baudson, Geraldine|Cattan, Stephane|Piessen, Guillaume|Pruvot, Francois-Rene | ||||||||||
| PMID: | 23564804 | ||||||||||
| 17. | |||||||||||
| Journal: | Toxicol In Vitro. 2013 Sep;27(6):1809-19. | ||||||||||
| Title: | Cylindrospermopsin induced transcriptional responses in human hepatoma HepG2 cells. | ||||||||||
| Author: | Straser, Alja|Filipic, Metka|Zegura, Bojana | ||||||||||
| PMID: | 23726867 | ||||||||||
| 18. | |||||||||||
| Journal: | Pharm Res. 2015 Mar;32(3):1141-57. | ||||||||||
| Title: | Significantly decreased and more variable expression of major CYPs and UGTs in liver microsomes prepared from HBV-positive human hepatocellular carcinoma and matched pericarcinomatous tissues determined using an isotope label-free UPLC-MS/MS method. | ||||||||||
| Author: | Yan, Tongmeng|Gao, Song|Peng, Xiaojuan|Shi, Jian|Xie, Cong|Li, Qiang|Lu, Linlin|Wang, Ying|Zhou, Fuyuan|Liu, Zhongqiu|Hu, Ming | ||||||||||
| PMID: | 25288013 | ||||||||||
| 19. | |||||||||||
| Journal: | PLoS One. 2015 May 26;10(5):e0127524. | ||||||||||
| Title: | Drug-Metabolizing Activity, Protein and Gene Expression of UDP-Glucuronosyltransferases Are Significantly Altered in Hepatocellular Carcinoma Patients. | ||||||||||
| Author: | Lu, Linlin|Zhou, Juan|Shi, Jian|Peng, Xiao-juan|Qi, Xiao-xiao|Wang, Ying|Li, Fang-Yuan|Zhou, Fu-Yuan|Liu, Liang|Liu, Zhong-Qiu | ||||||||||
| PMID: | 26010150 | ||||||||||
| 20. | |||||||||||
| Journal: | Genet Mol Res. 2015 May 18;14(2):5221-8. | ||||||||||
| Title: | Polymorphism of UGT1A1*28 (TA)7 and liver damage in hepatitis B virus-positive patients in Albania. | ||||||||||
| Author: | Marku, E|Maltese, P E|Koni, M|Capodicasa, N|Qendro, I S|Rigoni, E|Cecchin, S|Bertelli, M | ||||||||||
| PMID: | 26125716 | ||||||||||
| 21. | |||||||||||
| Journal: | Ann Surg Oncol. 2016 Jul;23(7):2161-6. | ||||||||||
| Title: | High Resectability Rate of Initially Unresectable Colorectal Liver Metastases After UGT1A1-Adapted High-Dose Irinotecan Combined with LV5FU2 and Cetuximab: A Multicenter Phase II Study (ERBIFORT). | ||||||||||
| Author: | Phelip, Jean Marc|Mineur, Laurent|De la Fouchardiere, Christelle|Chatelut, Etienne|Quesada, Jean Louis|Roblin, Xavier|Pezet, Denis|Mendoza, Christophe|Buc, Emmanuel|Rivoire, Michel | ||||||||||
| PMID: | 26739304 | ||||||||||
| 22. | |||||||||||
| Journal: | Ann Hepatol. 2016 Jul-Aug;15(4):568-76. | ||||||||||
| Title: | CUL4B, NEDD4, and UGT1As involve in the TGF-beta signalling in hepatocellular carcinoma. | ||||||||||
| Author: | Qu, Zhaowei|Li, Di|Xu, Haitao|Zhang, Rujia|Li, Bing|Sun, Chengming|Dong, Wei|Zhang, Yubao | ||||||||||
| PMID: | 27236156 | ||||||||||
| 23. | |||||||||||
| Journal: | Pharmacogenomics. 2016 Sep;17(14):1483-90. | ||||||||||
| Title: | Polymorphisms in SLCO1B1 and UGT1A1 are associated with sorafenib-induced toxicity. | ||||||||||
| Author: | Bins, Sander|Lenting, Anne|El Bouazzaoui, Samira|van Doorn, Leni|Oomen-de Hoop, Esther|Eskens, Ferry Alm|van Schaik, Ron Hn|Mathijssen, Ron Hj | ||||||||||
| PMID: | 27533851 | ||||||||||
| 24. | |||||||||||
| Journal: | Liver Int. 2017 Sep;37(9):1345-1353. | ||||||||||
| Title: | UGT1A polymorphisms as genetic biomarkers for hepatocellular carcinoma risk in Caucasian population. | ||||||||||
| Author: | De Mattia, Elena|Cecchin, Erika|Polesel, Jerry|Lupo, Francesco|Tiribelli, Claudio|Crovatto, Marina|Buonadonna, Angela|Toffoli, Giuseppe | ||||||||||
| PMID: | 28294511 | ||||||||||