Primary Site >> Colorectal Cancer

Gene >> UGCG

Journal: Int J Cancer. 2004 Jul 1;110(4):511-22.
Title: MRP1 and glucosylceramide are coordinately over expressed and enriched in rafts during multidrug resistance acquisition in colon cancer cells.
Author: Klappe, Karin|Hinrichs, John W J|Kroesen, Bart-Jan|Sietsma, Hannie|Kok, Jan Willem
PMID: 15122583
Journal: Mol Cancer Ther. 2004 May;3(5):633-9.
Title: Overexpression of glucosylceramide synthase and P-glycoprotein in cancer cells selected for resistance to natural product chemotherapy.
Author: Gouaze, Valerie|Yu, Jing Y|Bleicher, Richard J|Han, Tie-Yan|Liu, Yong-Yu|Wang, Hongtao|Gottesman, Michael M|Bitterman, Arie|Giuliano, Armando E|Cabot, Myles C
PMID: 15141021
Journal: Mol Cancer. 2010 Jun 11;9:145.
Title: Glucosylceramide synthase upregulates MDR1 expression in the regulation of cancer drug resistance through cSrc and beta-catenin signaling.
Author: Liu, Yong-Yu|Gupta, Vineet|Patwardhan, Gauri A|Bhinge, Kaustubh|Zhao, Yunfeng|Bao, Jianxiong|Mehendale, Harihara|Cabot, Myles C|Li, Yu-Teh|Jazwinski, S Michal
PMID: 20540746
Journal: Biochim Biophys Acta. 2012 Jul;1821(7):943-53.
Title: DNA damage induces down-regulation of UDP-glucose ceramide glucosyltransferase, increases ceramide levels and triggers apoptosis in p53-deficient cancer cells.
Author: Haynes, Teka-Ann S|Filippov, Valery|Filippova, Maria|Yang, Jun|Zhang, Kangling|Duerksen-Hughes, Penelope J
PMID: 22349266
Journal: J Exp Clin Cancer Res. 2012 Mar 16;31:23.
Title: GCS overexpression is associated with multidrug resistance of human HCT-8 colon cancer cells.
Author: Song, Min|Zang, Weidong|Zhang, Baohua|Cao, Jing|Yang, Guanrui
PMID: 22424291
Journal: Eur Rev Med Pharmacol Sci. 2014;18(23):3632-7.
Title: Expression and significance of glucosylceramide synthase in colorectal carcinoma tissues.
Author: Wang, C|Liu, J N|Xu, L|Mu, Y L|Sun, P
PMID: 25535133
Journal: PLoS One. 2017 Jan 12;12(1):e0169585.
Title: AT7867 Inhibits Human Colorectal Cancer Cells via AKT-Dependent and AKT-Independent Mechanisms.
Author: Zhang, Shihu|Deng, Zhengming|Yao, Chen|Huang, Ping|Zhang, Yi|Cao, Shibing|Li, Xiangcheng
PMID: 28081222