Primary Site >> Stomach Cancer
Gene >> TYMS
| 1. | |||||||||||
| Journal: | Gan No Rinsho. 1986 Nov;32(14):1838-40. | ||||||||||
| Title: | [Thymidylate synthase inhibition in malignant tumors after oral administration of UFT]. | ||||||||||
| Author: | Yamamura, M|Seiro, T|Yamamoto, M|Shirasaka, T|Miyauchi, S|Fujii, S | ||||||||||
| PMID: | 3099031 | ||||||||||
| 2. | |||||||||||
| Journal: | Cancer. 1989 May 1;63(9):1693-6. | ||||||||||
| Title: | 5-Fluorouracil and UFT-sensitive gastric carcinoma has a high level of thymidylate synthase. | ||||||||||
| Author: | Maehara, Y|Kusumoto, T|Kusumoto, H|Anai, H|Sakaguchi, Y|Kido, Y|Okamura, T|Korenaga, D|Sugimachi, K | ||||||||||
| PMID: | 2495166 | ||||||||||
| 3. | |||||||||||
| Journal: | Gan To Kagaku Ryoho. 1992 Jul;19(7):954-62. | ||||||||||
| Title: | [High-dose leucovorin and 5-FU]. | ||||||||||
| Author: | Sasaki, T | ||||||||||
| PMID: | 1626951 | ||||||||||
| 4. | |||||||||||
| Journal: | Gan To Kagaku Ryoho. 1995 Nov;22(13):1947-51. | ||||||||||
| Title: | [UFT/CDDP preoperative chemotherapy for progressive gastric cancer--histological antitumor effects and thymidylate synthase inhibition rate]. | ||||||||||
| Author: | Tanaka, S|Umeno, T|Mitsuishi, K|Tomita, A|Ootsuka, K|Mori, H|Nakamura, H|Ikeda, S | ||||||||||
| PMID: | 7487125 | ||||||||||
| 5. | |||||||||||
| Journal: | J Clin Oncol. 1996 Jan;14(1):176-82. | ||||||||||
| Title: | Thymidylate synthase mRNA level in adenocarcinoma of the stomach: a predictor for primary tumor response and overall survival. | ||||||||||
| Author: | Lenz, H J|Leichman, C G|Danenberg, K D|Danenberg, P V|Groshen, S|Cohen, H|Laine, L|Crookes, P|Silberman, H|Baranda, J|Garcia, Y|Li, J|Leichman, L | ||||||||||
| PMID: | 8558194 | ||||||||||
| 6. | |||||||||||
| Journal: | Ann Oncol. 1996 Mar;7(3):283-9. | ||||||||||
| Title: | Critical factors for optimizing the 5-fluorouracil-folinic acid association in cancer chemotherapy. | ||||||||||
| Author: | Etienne, M C|Guillot, T|Milano, G | ||||||||||
| PMID: | 8740793 | ||||||||||
| 7. | |||||||||||
| Journal: | Clin Cancer Res. 1998 Jun;4(6):1469-74. | ||||||||||
| Title: | Biological markers as a predictor for response and prognosis of unresectable gastric cancer patients treated with 5-fluorouracil and cis-platinum. | ||||||||||
| Author: | Boku, N|Chin, K|Hosokawa, K|Ohtsu, A|Tajiri, H|Yoshida, S|Yamao, T|Kondo, H|Shirao, K|Shimada, Y|Saito, D|Hasebe, T|Mukai, K|Seki, S|Saito, H|Johnston, P G | ||||||||||
| PMID: | 9626464 | ||||||||||
| 8. | |||||||||||
| Journal: | Gan To Kagaku Ryoho. 1998 Jul;25(8):1165-71. | ||||||||||
| Title: | [The intratumoral levels of thymidylate synthetase and folate in gastric and colon cancer]. | ||||||||||
| Author: | Iba, T|Yagi, Y|Kidokoro, A|Ishi, K|Koyatsu, J | ||||||||||
| PMID: | 9679579 | ||||||||||
| 9. | |||||||||||
| Journal: | Br J Cancer. 2001 Jan;84(2):186-92. | ||||||||||
| Title: | Expression of thymidylate synthase in gastric cancer patients treated with 5-fluorouracil and doxorubicin-based adjuvant chemotherapy after curative resection. | ||||||||||
| Author: | Choi, J|Lim, H|Nam, D K|Kim, H S|Cho, D Y|Yi, J W|Kim, H C|Cho, Y K|Kim, M W|Joo, H J|Lee, K B|Kim, K B | ||||||||||
| PMID: | 11161374 | ||||||||||
| 10. | |||||||||||
| Journal: | Surg Today. 2001;31(4):340-5. | ||||||||||
| Title: | Gastric cancer with Virchow's and multiple lung metastases showing a remarkable response to preoperative chemotherapy: report of a case. | ||||||||||
| Author: | Nozawa, H|Sekikawa, T|Tsukui, H|Kina, S|Kawahara, T|Ono, K|Kishida, Y|Yakumaru, K|Kagami, H | ||||||||||
| PMID: | 11321346 | ||||||||||
| 11. | |||||||||||
| Journal: | Int J Oncol. 2001 Aug;19(2):341-6. | ||||||||||
| Title: | Changes in intratumoral thymidylate synthase (TS) and dihydropyrimidine dehydrogenase (DPD) mRNA expression in colorectal and gastric cancer during continuous tegafur infusion. | ||||||||||
| Author: | Uchida, K|Hayashi, K|Kuramochi, H|Takasaki, K | ||||||||||
| PMID: | 11445849 | ||||||||||
| 12. | |||||||||||
| Journal: | Cancer Chemother Pharmacol. 2002 Feb;49(2):111-8. | ||||||||||
| Title: | Synergistic cytotoxic effect between serine-threonine phosphatase inhibitors and 5-fluorouracil: a novel concept for modulation of cytotoxic effect. | ||||||||||
| Author: | Islam, Md Muzharul|Begum, Salma|Lin, Ling|Okamura, Atsushi|Du, Ming|Fujimura, Shinji | ||||||||||
| PMID: | 11862424 | ||||||||||
| 13. | |||||||||||
| Journal: | Anticancer Res. 2002 Jan-Feb;22(1A):339-41. | ||||||||||
| Title: | Human colorectal malignancy and oral UFT. | ||||||||||
| Author: | Sakamoto, Shinobu|Tsukada, Kunio|Sagara, Tetsuro|Kawachi, Yasuyuki|Murakami, Saburo|Iwama, Takeo | ||||||||||
| PMID: | 12017314 | ||||||||||
| 14. | |||||||||||
| Journal: | Anticancer Res. 2002 Sep-Oct;22(5):2805-9. | ||||||||||
| Title: | Association of thymidylate synthase gene polymorphism with its mRNA and protein expression and with prognosis in gastric cancer. | ||||||||||
| Author: | Ishida, Yoshinori|Kawakami, Kazuyuki|Tanaka, Yoko|Kanehira, Eiji|Omura, Kenji|Watanabe, Go | ||||||||||
| PMID: | 12530000 | ||||||||||
| 15. | |||||||||||
| Journal: | Cancer Lett. 2003 Apr 25;193(2):127-31. | ||||||||||
| Title: | Differential alternative splicing expressions of thymidylate synthase isoforms. | ||||||||||
| Author: | Hisatomi, Hisashi|Tanemura, Hiromi|Iizuka, Toshiro|Katsumata, Kenji|Nagao, Kumi|Sumida, Hitomi|Udagawa, Harushi|Hikiji, Kazumasa | ||||||||||
| PMID: | 12706868 | ||||||||||
| 16. | |||||||||||
| Journal: | Gan To Kagaku Ryoho. 2004 Sep;31(9):1347-50. | ||||||||||
| Title: | [The association of expression and gene polymorphism of the thymidylate synthase gene with 5-fluoro-5'-deoxyuridine sensitivity in gastric cancer cell lines]. | ||||||||||
| Author: | Kaneko, Mami|Kawakami, Kazuyuki|Oyama, Kanako|Endo, Yoshio|Tanaka, Motohiro|Sasaki, Takuma|Watanabe, Go | ||||||||||
| PMID: | 15446554 | ||||||||||
| 17. | |||||||||||
| Journal: | Int J Cancer. 2004 Dec 20;112(6):1010-4. | ||||||||||
| Title: | Association of thymidylate synthase polymorphisms with gastric cancer susceptibility. | ||||||||||
| Author: | Graziano, Francesco|Kawakami, Kazuyuki|Watanabe, Go|Ruzzo, Annamaria|Humar, Bostjan|Santini, Daniele|Catalano, Vincenzo|Ficarelli, Rita|Merriman, Tony|Panunzi, Simona|Testa, Enrica|Cascinu, Stefano|Bearzi, Italo|Tonini, Giuseppe|Magnani, Mauro | ||||||||||
| PMID: | 15386366 | ||||||||||
| 18. | |||||||||||
| Journal: | Anticancer Res. 2004 Jul-Aug;24(4):2455-63. | ||||||||||
| Title: | Thymidylate synthetase (TS) genotype and TS/dihydropyrimidine dehydrogenase mRNA level as an indicator in determining chemosensitivity to 5-fluorouracil in advanced gastric carcinoma. | ||||||||||
| Author: | Toriumi, Fumiki|Kubota, Tetsuro|Saikawa, Yoshiro|Yoshida, Masashi|Otani, Yoshihide|Watanabe, Masahiko|Kumai, Koichiro|Kitajima, Masaki | ||||||||||
| PMID: | 15330198 | ||||||||||
| 19. | |||||||||||
| Journal: | Gastric Cancer. 2004;7(2):110-6. | ||||||||||
| Title: | Changes in thymidylate synthase and its inhibition rate and changes in dihydropyrimidine dehydrogenase after the administration of 5-fluorouracil with cisplatin to nude mice with gastric cancer xenograft SC-1-NU. | ||||||||||
| Author: | Sakurai, Yoichi|Uraguchi, Takashi|Imazu, Hiroki|Hasegawa, Shigeru|Matsubara, Toshiki|Ochiai, Masahiro|Funabiki, Takahiko | ||||||||||
| PMID: | 15224198 | ||||||||||
| 20. | |||||||||||
| Journal: | Cancer Chemother Pharmacol. 2004 Apr;53(4):337-40. | ||||||||||
| Title: | Phase II clinical trial of parenteral hydroxyurea in combination with fluorouracil, interferon and filgrastim in the treatment of advanced pancreatic, gastric and neuroendocrine tumors. | ||||||||||
| Author: | Kaubisch, Andreas|Kaleya, Ron|Haynes, Hilda|Rozenblit, Alla|Wadler, Scott | ||||||||||
| PMID: | 14704829 | ||||||||||
| 21. | |||||||||||
| Journal: | Asian Pac J Cancer Prev. 2004 Apr-Jun;5(2):133-8. | ||||||||||
| Title: | Polymorphisms in thymidylate synthase and methylenetetrahydrofolate reductase genes and the susceptibility to esophageal and stomach cancer with smoking. | ||||||||||
| Author: | Gao, Chang-Ming|Takezaki, Toshiro|Wu, Jian-Zhong|Liu, Yan-Ting|Ding, Jian-Hua|Li, Su-Ping|Su, Ping|Hu, Xu|Kai, Hai-Tao|Li, Zong-You|Matsuo, Keitaro|Hamajima, Nobuyuki|Sugimura, Haruhiko|Tajima, Kazuo | ||||||||||
| PMID: | 15244514 | ||||||||||
| 22. | |||||||||||
| Journal: | Gan To Kagaku Ryoho. 2005 Feb;32(2):183-7. | ||||||||||
| Title: | [Assessment of dihydropyrimidine dehydrogenase and thymidylate synthase expression in gastric carcinoma and colonic carcinoma]. | ||||||||||
| Author: | Yoshida, Toru|Shimooki, Osamu|Baba, Yuko|Abe, Tadashi|Sugai, Tamotsu|Nakamura, Shin-ichi | ||||||||||
| PMID: | 15751630 | ||||||||||
| 23. | |||||||||||
| Journal: | Clin Cancer Res. 2005 May 15;11(10):3778-83. | ||||||||||
| Title: | Prognostic role of thymidylate synthase polymorphisms in gastric cancer patients treated with surgery and adjuvant chemotherapy. | ||||||||||
| Author: | Kawakami, Kazuyuki|Graziano, Francesco|Watanabe, Go|Ruzzo, Annamaria|Santini, Daniele|Catalano, Vincenzo|Bisonni, Renato|Arduini, Federica|Bearzi, Italo|Cascinu, Stefano|Muretto, Pietro|Perrone, Giuseppe|Rabitti, Carla|Giustini, Lucio|Tonini, Giuseppe|Piz | ||||||||||
| PMID: | 15897576 | ||||||||||
| 24. | |||||||||||
| Journal: | Carcinogenesis. 2005 Oct;26(10):1764-9. Epub 2005 Jun 1. | ||||||||||
| Title: | Polymorphisms of thymidylate synthase in the 5'- and 3'-untranslated regions associated with risk of gastric cancer in South China: a case-control analysis. | ||||||||||
| Author: | Zhang, Zhengdong|Xu, Yaochu|Zhou, Jianwei|Wang, Xinru|Wang, Liwei|Hu, Xu|Guo, Jiangtao|Wei, Qingyi|Shen, Hongbing | ||||||||||
| PMID: | 15930032 | ||||||||||
| 25. | |||||||||||
| Journal: | Korean J Gastroenterol. 2005 Jul;46(1):32-8. | ||||||||||
| Title: | [Clinical significance of thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphism in Korean patients with gastric cancer]. | ||||||||||
| Author: | Lee, Jun|Jeong, Cheol Kweon|Hong, Sung Pyo|Chong, So Young|Oh, Doyeun|Hwang, Seong Gyu|Ahn, Dae Ho|Kim, Sehyun|Han, Jin Hee|Kim, Nam Keun | ||||||||||
| PMID: | 16030402 | ||||||||||
| 26. | |||||||||||
| Journal: | Jpn J Clin Oncol. 2005 Dec;35(12):714-9. | ||||||||||
| Title: | Biological markers as a predictor for response and prognosis of unresectable gastric cancer patients treated with irinotecan and cisplatin. | ||||||||||
| Author: | Nagashima, Fumio|Boku, Narikazu|Ohtsu, Atsushi|Yoshida, Shigeaki|Hasebe, Takahiro|Ochiai, Atsushi|Sakata, Yu|Saito, Hiroshi|Miyata, Yoshinori|Hyodo, Ichinosuke|Ando, Masahiko | ||||||||||
| PMID: | 16303791 | ||||||||||
| 27. | |||||||||||
| Journal: | Hepatogastroenterology. 2006 May-Jun;53(69):458-62. | ||||||||||
| Title: | Intratumoral heterogeneous expression of thymidylate synthase in gastric cancer. | ||||||||||
| Author: | Chung-Kang, Cheng|Ohno, Masakazu|Nishimura, Koji|Kuroda, Yoshikazu | ||||||||||
| PMID: | 16795992 | ||||||||||
| 28. | |||||||||||
| Journal: | Oncol Rep. 2006 Oct;16(4):721-7. | ||||||||||
| Title: | Expression of chemoresistance-related proteins in alpha-fetoprotein-producing adenocarcinoma of the digestive organs. | ||||||||||
| Author: | Kamoshida, Shingo|Suzuki, Mai|Sakurai, Yoichi|Ochiai, Masahiro|Kimura, Fumikazu|Kuwao, Sadahito|Sakamoto, Kazuki|Sugimoto, Yoshikazu|Fukushima, Masakazu|Tsutsumi, Yutaka | ||||||||||
| PMID: | 16969485 | ||||||||||
| 29. | |||||||||||
| Journal: | Gastric Cancer. 2006;9(3):145-55. | ||||||||||
| Title: | Prediction of clinical outcome of fluoropyrimidine-based chemotherapy for gastric cancer patients, in terms of the 5-fluorouracil metabolic pathway. | ||||||||||
| Author: | Ichikawa, Wataru | ||||||||||
| PMID: | 16952032 | ||||||||||
| 30. | |||||||||||
| Journal: | Gan To Kagaku Ryoho. 2006 Jun;33 Suppl 1:83-6. | ||||||||||
| Title: | [Combination chemotherapy of S-1 and docetaxel on advanced and recurrent gastric cancer]. | ||||||||||
| Author: | Yoshida, Kazuhiro|Wada, Yoshiyuki|Tanabe, Kazuaki|Ukon, Kei|Hihara, Jyun | ||||||||||
| PMID: | 16897978 | ||||||||||
| 31. | |||||||||||
| Journal: | Curr Opin Pharmacol. 2006 Aug;6(4):337-44. | ||||||||||
| Title: | Determinants of chemosensitivity in gastric cancer. | ||||||||||
| Author: | Park, David J|Lenz, Heinz-Josef | ||||||||||
| PMID: | 16777480 | ||||||||||
| 32. | |||||||||||
| Journal: | J Hum Genet. 2006;51(3):155-60. | ||||||||||
| Title: | Polymorphism in the 3'-untranslated region of the thymidylate synthase gene and sensitivity of stomach cancer to fluoropyrimidine-based chemotherapy. | ||||||||||
| Author: | Lu, Jian-Wei|Gao, Chang-Ming|Wu, Jian-Zhong|Cao, Hai-Xia|Tajima, Kazuo|Feng, Ji-Feng | ||||||||||
| PMID: | 16424979 | ||||||||||
| 33. | |||||||||||
| Journal: | Br J Cancer. 2007 Aug 6;97(3):334-44. | ||||||||||
| Title: | Combined modalities of resistance in an oxaliplatin-resistant human gastric cancer cell line with enhanced sensitivity to 5-fluorouracil. | ||||||||||
| Author: | Chen, C-C|Chen, L-T|Tsou, T-C|Pan, W-Y|Kuo, C-C|Liu, J-F|Yeh, S-C|Tsai, F-Y|Hsieh, H-P|Chang, J-Y | ||||||||||
| PMID: | 17609664 | ||||||||||
| 34. | |||||||||||
| Journal: | Anticancer Res. 2007 Jul-Aug;27(4C):2973-83. | ||||||||||
| Title: | Expression of a molecular marker panel as a prognostic tool in gastric cancer patients treated postoperatively with docetaxel and irinotecan. A study of the Hellenic Cooperative Oncology Group. | ||||||||||
| Author: | Skarlos, Dimosthenis V|Bai, Maria|Goussia, Anna|Samantas, Epaminontas|Galani, Eleni|Tsavdaridis, Dimitrios|Karina, Maria|Papakostas, Pavlos|Konstantara, Athina|Fountzilas, George | ||||||||||
| PMID: | 17695481 | ||||||||||
| 35. | |||||||||||
| Journal: | Br J Cancer. 2008 Apr 22;98(8):1398-402. | ||||||||||
| Title: | ERCC1 mRNA levels and survival of advanced gastric cancer patients treated with a modified FOLFOX regimen. | ||||||||||
| Author: | Wei, J|Zou, Z|Qian, X|Ding, Y|Xie, L|Sanchez, J J|Zhao, Y|Feng, J|Ling, Y|Liu, Y|Yu, L|Rosell, R|Liu, B | ||||||||||
| PMID: | 18362936 | ||||||||||
| 36. | |||||||||||
| Journal: | Int J Clin Oncol. 2008 Jun;13(3):206-11. | ||||||||||
| Title: | Challenges in predicting the clinical outcome in S-1-based chemotherapy for gastric cancer patients. | ||||||||||
| Author: | Ichikawa, Wataru|Sasaki, Yasutsuna | ||||||||||
| PMID: | 18553229 | ||||||||||
| 37. | |||||||||||
| Journal: | BMC Cancer. 2008 Jul 25;8:210. | ||||||||||
| Title: | Efficacy of laser capture microdissection plus RT-PCR technique in analyzing gene expression levels in human gastric cancer and colon cancer. | ||||||||||
| Author: | Makino, Hiroshi|Uetake, Hiroyuki|Danenberg, Kathleen|Danenberg, Peter V|Sugihara, Kenichi | ||||||||||
| PMID: | 18652704 | ||||||||||
| 38. | |||||||||||
| Journal: | Hepatogastroenterology. 2008 Sep-Oct;55(86-87):1882-6. | ||||||||||
| Title: | The discrepancy in thymidylate synthase and dihydropyrimidine dehydrogenase expression depending on measurement methodologies in stage 4 gastric cancer. | ||||||||||
| Author: | Akamoto, Shintaro|Usuki, Hisashi|Haba, Reiji|Kakinoki, Keitarou|Okano, Keiichi|Izuishi, Kunihiko|Wakabayashi, Hisao|Suzuki, Yasuyuki | ||||||||||
| PMID: | 19102414 | ||||||||||
| 39. | |||||||||||
| Journal: | J Gastroenterol Hepatol. 2009 Jun;24(6):970-81. | ||||||||||
| Title: | Pharmacogenetics of fluoropyrimidine and cisplatin. A future application to gastric cancer treatment. | ||||||||||
| Author: | Shimoyama, Shouji | ||||||||||
| PMID: | 19638079 | ||||||||||
| 40. | |||||||||||
| Journal: | Dig Dis Sci. 2009 Jul;54(7):1379-85. | ||||||||||
| Title: | Polymorphisms of thymidylate synthase in the 5'- and 3'-untranslated regions and gastric cancer. | ||||||||||
| Author: | Zhuang, Wen|Wu, Xiao-Ting|Zhou, Yong|Liu, Guan-Jian|Wu, Tai-Xiang|Yao, Xun|Du, Liang|Wei, Mao-Ling | ||||||||||
| PMID: | 18989779 | ||||||||||
| 41. | |||||||||||
| Journal: | Oncol Rep. 2009 Jul;22(1):127-36. | ||||||||||
| Title: | Comprehensive analysis of excision repair complementation group 1, glutathione S-transferase, thymidylate synthase and uridine diphosphate glucuronosyl transferase 1A1 polymorphisms predictive for treatment outcome in patients with advanced gastric cancer | ||||||||||
| Author: | Seo, Bong-Gun|Kwon, Hyuk-Chan|Oh, Sung Yong|Lee, Suee|Kim, Sung-Gun|Kim, Sung-Hyun|Han, Hoon|Kim, Hyo-Jin | ||||||||||
| PMID: | 19513514 | ||||||||||
| 42. | |||||||||||
| Journal: | Cancer Sci. 2010 May;101(5):1247-54. | ||||||||||
| Title: | BRCA1 and XRCC1 polymorphisms associated with survival in advanced gastric cancer treated with taxane and cisplatin. | ||||||||||
| Author: | Shim, Hyun Jeong|Yun, Joo Young|Hwang, Jun Eul|Bae, Woo Kyun|Cho, Sang Hee|Lee, Ji Hee|Kim, Hee Nam|Shin, Min Ho|Kweon, Sun Seog|Lee, Jae Hyuk|Kim, Hyeoung Joon|Chung, Ik Joo | ||||||||||
| PMID: | 20331623 | ||||||||||
| 43. | |||||||||||
| Journal: | Int J Oncol. 2010 May;36(5):1193-200. | ||||||||||
| Title: | The role of thymidine phosphorylase in the induction of early growth response protein-1 and thrombospondin-1 by 5-fluorouracil in human cancer carcinoma cells. | ||||||||||
| Author: | Matsushita, Shigeto|Ikeda, Ryuji|Nishizawa, Yukihiko|Che, Xiao-Fang|Furukawa, Tatsuhiko|Miyadera, Kazutaka|Tabata, Sho|Ushiyama, Mina|Tajitsu, Yusuke|Yamamoto, Masatatsu|Takeda, Yasuo|Minami, Kentaro|Mataki, Hironori|Kanzaki, Tamotsu|Yamada, Katsushi|Kane | ||||||||||
| PMID: | 20372793 | ||||||||||
| 44. | |||||||||||
| Journal: | Cancer Epidemiol Biomarkers Prev. 2010 May;19(5):1311-9. | ||||||||||
| Title: | Folate intake along with genetic polymorphisms in methylenetetrahydrofolate reductase and thymidylate synthase in patients with advanced gastric cancer. | ||||||||||
| Author: | Shitara, Kohei|Muro, Kei|Ito, Seiji|Sawaki, Akira|Tajika, Masahiro|Kawai, Hiroki|Yokota, Tomoya|Takahari, Daisuke|Shibata, Takashi|Ura, Takashi|Ito, Hidemi|Hosono, Satoyo|Kawase, Takakazu|Watanabe, Miki|Tajima, Kazuo|Yatabe, Yasushi|Tanaka, Hideo|Matsuo, | ||||||||||
| PMID: | 20447923 | ||||||||||
| 45. | |||||||||||
| Journal: | Anticancer Res. 2010 Jun;30(6):2325-30. | ||||||||||
| Title: | Polymorphisms of thymidylate synthase gene 5'- and 3'-untranslated region and risk of gastric cancer in Koreans. | ||||||||||
| Author: | Yim, Dong Jin|Kim, Ok Jun|An, Hee Jung|Kang, Haeyoun|Ahn, Dae Ho|Hwang, Seong Gyu|Oh, Doyeun|Kim, Nam Keun | ||||||||||
| PMID: | 20651387 | ||||||||||
| 46. | |||||||||||
| Journal: | Chemotherapy. 2010;56(4):313-7. | ||||||||||
| Title: | Genetic polymorphisms associated with 5-Fluorouracil-induced neurotoxicity. | ||||||||||
| Author: | Kim, Suk-Ran|Park, Chang-Hun|Park, Silvia|Park, Joon-Oh|Lee, Jeeyun|Lee, Soo-Youn | ||||||||||
| PMID: | 20714149 | ||||||||||
| 47. | |||||||||||
| Journal: | Cancer Sci. 2010 Mar;101(3):793-9. | ||||||||||
| Title: | Epidermal growth factor receptor intron 1 CA dinucleotide repeat polymorphism and survival of advanced gastric cancer patients treated with cetuximab plus modified FOLFOX6. | ||||||||||
| Author: | Han, Sae-Won|Oh, Do-Youn|Im, Seock-Ah|Park, Sook Ryun|Lee, Keun-Wook|Song, Hong Suk|Lee, Nam-Su|Lee, Kyung Hee|Choi, In Sil|Lee, Moon Hee|Kim, Min A|Kim, Woo Ho|Bang, Yung-Jue|Kim, Tae-You | ||||||||||
| PMID: | 20047592 | ||||||||||
| 48. | |||||||||||
| Journal: | Anticancer Res. 2011 Nov;31(11):3691-6. | ||||||||||
| Title: | Antitumour activity of S-1 in combination with cetuximab on human gastric cancer cell lines in vivo. | ||||||||||
| Author: | Kobunai, Takashi|Watanabe, Toshiaki|Fukusato, Toshio | ||||||||||
| PMID: | 22110188 | ||||||||||
| 49. | |||||||||||
| Journal: | PLoS One. 2011;6(9):e24662. | ||||||||||
| Title: | Gene expression signature analysis identifies vorinostat as a candidate therapy for gastric cancer. | ||||||||||
| Author: | Claerhout, Sofie|Lim, Jae Yun|Choi, Woonyoung|Park, Yun-Yong|Kim, Kyounghyun|Kim, Sang-Bae|Lee, Ju-Seog|Mills, Gordon B|Cho, Jae Yong | ||||||||||
| PMID: | 21931799 | ||||||||||
| 50. | |||||||||||
| Journal: | Cancer Sci. 2011 Aug;102(8):1509-15. | ||||||||||
| Title: | Calpain regulates thymidylate synthase-5-fluoro-dUMP complex levels associated with response to 5-fluorouracil in gastric cancer cells. | ||||||||||
| Author: | Nabeya, Yoshihiro|Suzuki, Takao|Furuya, Aki|Koide, Naoki|Ohkoshi, Motohiro|Takiguchi, Masaki|Ochiai, Takenori|Matsubara, Hisahiro|Hiwasa, Takaki | ||||||||||
| PMID: | 21561529 | ||||||||||
| 51. | |||||||||||
| Journal: | Cancer Sci. 2011 Jul;102(7):1388-95. | ||||||||||
| Title: | Antitumor activity of NVP-AUY922, a novel heat shock protein 90 inhibitor, in human gastric cancer cells is mediated through proteasomal degradation of client proteins. | ||||||||||
| Author: | Lee, Kyung-Hun|Lee, Ju-Hee|Han, Sae-Won|Im, Seock-Ah|Kim, Tae-You|Oh, Do-Youn|Bang, Yung-Jue | ||||||||||
| PMID: | 21453385 | ||||||||||
| 52. | |||||||||||
| Journal: | Biomarkers. 2011 Feb;16(1):74-82. | ||||||||||
| Title: | Clinicopathologic significance of ERCC1, thymidylate synthase and glutathione S-transferase P1 expression for advanced gastric cancer patients receiving adjuvant 5-FU and cisplatin chemotherapy. | ||||||||||
| Author: | Kim, Ki Han|Kwon, Hyuk-Chan|Oh, Sung Yong|Kim, Sung Hyun|Lee, Suee|Kwon, Kyung A|Jang, Jin Seok|Kim, Min Chan|Kim, Su-Jin|Kim, Hyo-Jin | ||||||||||
| PMID: | 21133646 | ||||||||||
| 53. | |||||||||||
| Journal: | Cancer Biother Radiopharm. 2012 Jun;27(5):299-306. | ||||||||||
| Title: | Enhancement of anticancer efficacy of chemotherapeutics by gambogic acid against gastric cancer cells. | ||||||||||
| Author: | Zou, Zheng-Yun|Wei, Jia|Li, Xiao-Lin|Yu, Li-Xia|Wang, Ting-Ting|Qian, Xiao-Ping|Liu, Bao-Rui | ||||||||||
| PMID: | 22444164 | ||||||||||
| 54. | |||||||||||
| Journal: | Asian Pac J Cancer Prev. 2012;13(5):1923-7. | ||||||||||
| Title: | 2R of thymidylate synthase 5'-untranslated enhanced region contributes to gastric cancer risk: a meta-analysis. | ||||||||||
| Author: | Yang, Zhen|Liu, Hong-Xiang|Zhang, Xie-Fu | ||||||||||
| PMID: | 22901148 | ||||||||||
| 55. | |||||||||||
| Journal: | Infect Agent Cancer. 2012 Aug 28;7(1):21. | ||||||||||
| Title: | Epstein-barr virus infected gastric adenocarcinoma expresses latent and lytic viral transcripts and has a distinct human gene expression profile. | ||||||||||
| Author: | Tang, Weihua|Morgan, Douglas R|Meyers, Michael O|Dominguez, Ricardo L|Martinez, Enrique|Kakudo, Kennichi|Kuan, Pei Fen|Banet, Natalie|Muallem, Hind|Woodward, Kimberly|Speck, Olga|Gulley, Margaret L | ||||||||||
| PMID: | 22929309 | ||||||||||
| 56. | |||||||||||
| Journal: | Asian Pac J Cancer Prev. 2012;13(6):2605-10. | ||||||||||
| Title: | 3R variant of thymidylate synthase 5'-untranslated enhanced region contributes to colorectal cancer risk: a meta-analysis. | ||||||||||
| Author: | Lu, Min|Sun, Luhaoran|Yang, Jing|Li, Yue-Yao | ||||||||||
| PMID: | 22938428 | ||||||||||
| 57. | |||||||||||
| Journal: | Mol Biol Rep. 2013 Jul;40(7):4637-44. | ||||||||||
| Title: | An integrated analysis of the association between Ts gene polymorphisms and clinical outcome in gastric and colorectal cancer patients treated with 5-FU-based regimens. | ||||||||||
| Author: | Wang, Ying-Chao|Xue, Hui-Ping|Wang, Zhen-Hua|Fang, Jing-Yuan | ||||||||||
| PMID: | 23645036 | ||||||||||
| 58. | |||||||||||
| Journal: | Ann Oncol. 2013 Oct;24(10):2560-5. | ||||||||||
| Title: | Impact of excision repair cross-complementing gene 1 (ERCC1) on the outcomes of patients with advanced gastric cancer: correlative study in Japan Clinical Oncology Group Trial JCOG9912. | ||||||||||
| Author: | Yamada, Y|Boku, N|Nishina, T|Yamaguchi, K|Denda, T|Tsuji, A|Hamamoto, Y|Konishi, K|Tsuji, Y|Amagai, K|Ohkawa, S|Fujita, Y|Nishisaki, H|Kawai, H|Takashima, A|Mizusawa, J|Nakamura, K|Ohtsu, A | ||||||||||
| PMID: | 23884439 | ||||||||||
| 59. | |||||||||||
| Journal: | PLoS One. 2014 Sep 18;9(9):e107424. | ||||||||||
| Title: | Thymidylate synthase genotype-directed chemotherapy for patients with gastric and gastroesophageal junction cancers. | ||||||||||
| Author: | Goff, Laura W|Thakkar, Nilay|Du, Liping|Chan, Emily|Tan, Benjamin R|Cardin, Dana B|McLeod, Howard L|Berlin, Jordan D|Zehnbauer, Barbara|Fournier, Chloe|Picus, Joel|Wang-Gillam, Andrea|Lee, Wooin|Lockhart, A Craig | ||||||||||
| PMID: | 25232828 | ||||||||||
| 60. | |||||||||||
| Journal: | Eur J Med Res. 2014 Sep 16;19:50. | ||||||||||
| Title: | Joint detection of ERCC1, TUBB3, and TYMS guidance selection of docetaxel, 5-fluorouracil and cisplatin (DDP) individual chemotherapy in advanced gastric cancer patients. | ||||||||||
| Author: | Luo, Yushuang|Li, Zhanquan|Cui, Sen|Shen, Cunfang|Zhao, Junhui|Wu, Milu|Li, Yuying|Wang, Miaozhou|Chen, Rong|Liu, Zhibo|Ri-Li, Ge | ||||||||||
| PMID: | 25223338 | ||||||||||
| 61. | |||||||||||
| Journal: | Zhongguo Zhong Xi Yi Jie He Za Zhi. 2014 Feb;34(2):224-9. | ||||||||||
| Title: | [Synergistic interaction between melittin and chemotherapeutic agents and their possible mechanisms: an experimental research]. | ||||||||||
| Author: | Wang, Rui-Ping|Huang, Shu-Ran|Zhou, Jin-Yong|Zou, Xi | ||||||||||
| PMID: | 24672950 | ||||||||||
| 62. | |||||||||||
| Journal: | Med Oncol. 2014 Feb;31(2):825. | ||||||||||
| Title: | Thymidylate synthase polymorphism in sporadic colorectal and gastric cancer in Tunisian population: a predictive role in 5-fluorouracil based chemotherapy treatment. | ||||||||||
| Author: | Baroudi, Olfa|Baroudi, Thouraya|Omrane, Ines|Moussa, Amel|Mezlini, Amel|Ayari, Hajer|Guermazi, Sami|Bahloul, Abdesslem|Bouzaienne, Hassen|Uhrhammer, Nancy|Bignon, Yves Jean|El-Gaaied, Amel Benammar|Bougatef, Karim | ||||||||||
| PMID: | 24415354 | ||||||||||
| 63. | |||||||||||
| Journal: | Gastric Cancer. 2014 Jan;17(1):188-95. | ||||||||||
| Title: | Enhancement of 5-fluorouracil-induced cytotoxicity by leucovorin in 5-fluorouracil-resistant gastric cancer cells with upregulated expression of thymidylate synthase. | ||||||||||
| Author: | Nakamura, Ayako|Nakajima, Go|Okuyama, Ryuji|Kuramochi, Hidekazu|Kondoh, Yurin|Kanemura, Toshinori|Takechi, Teiji|Yamamoto, Masakazu|Hayashi, Kazuhiko | ||||||||||
| PMID: | 23494117 | ||||||||||
| 64. | |||||||||||
| Journal: | Tumour Biol. 2014 Dec;35(12):12409-14. | ||||||||||
| Title: | Correlation between expression of thymidylate synthase and clinical outcome of advanced gastric cancer treated with capecitabine alone chemotherapy. | ||||||||||
| Author: | Liu, Xin Fu|Zhang, Hui|Sun, Jian Qun|Yin, Chan|Liu, Teng Fei|Yang, Hua|Chen, Long Hua | ||||||||||
| PMID: | 25185651 | ||||||||||
| 65. | |||||||||||
| Journal: | Mol Carcinog. 2015 Sep;54(9):880-8. | ||||||||||
| Title: | Genetic polymorphisms in the microRNA binding-sites of the thymidylate synthase gene predict risk and survival in gastric cancer. | ||||||||||
| Author: | Shen, Rong|Liu, Hongliang|Wen, Juyi|Liu, Zhensheng|Wang, Li-E|Wang, Qiming|Tan, Dongfeng|Ajani, Jaffer A|Wei, Qingyi | ||||||||||
| PMID: | 24756984 | ||||||||||
| 66. | |||||||||||
| Journal: | Gastric Cancer. 2015 Jul;18(3):538-48. | ||||||||||
| Title: | Impact of the expression of thymidylate synthase and dihydropyrimidine dehydrogenase genes on survival in stage II/III gastric cancer. | ||||||||||
| Author: | Sasako, Mitsuru|Terashima, Masanori|Ichikawa, Wataru|Ochiai, Atsushi|Kitada, Koji|Kurahashi, Issei|Sakuramoto, Shinichi|Katai, Hitoshi|Sano, Takeshi|Imamura, Hiroshi | ||||||||||
| PMID: | 25112781 | ||||||||||
| 67. | |||||||||||
| Journal: | Eur J Med Res. 2015 Mar 26;20:29. | ||||||||||
| Title: | Retraction note: Joint detection of ERCC1, TUBB3, and TYMS guidance selection of docetaxel, 5-fluorouracil and cisplatin (DDP) individual chemotherapy in advanced gastric cancer patients. | ||||||||||
| Author: | |||||||||||
| PMID: | 25888862 | ||||||||||
| 68. | |||||||||||
| Journal: | Medicine (Baltimore). 2015 Jul;94(27):e1091. | ||||||||||
| Title: | Delimiting Allelic Imbalance of TYMS by Allele-Specific Analysis. | ||||||||||
| Author: | Balboa-Beltran, Emilia|Cruz, Raquel|Carracedo, Angel|Barros, Francisco | ||||||||||
| PMID: | 26166093 | ||||||||||
| 69. | |||||||||||
| Journal: | Am J Transl Res. 2015 Aug 15;7(8):1429-39. eCollection 2015. | ||||||||||
| Title: | Delineation of gastric cancer subtypes by co-regulated expression of receptor tyrosine kinases and chemosensitivity genes. | ||||||||||
| Author: | Li, Shu-Chun|Ma, Rong|Wu, Jian-Zhong|Xiao, Xia|Wu, Wei|Li, Gang|Chen, Bo|Sharma, Ashok|Bai, Shan|Dun, Bo-Ying|She, Jin-Xiong|Tang, Jin-Hai | ||||||||||
| PMID: | 26396673 | ||||||||||
| 70. | |||||||||||
| Journal: | Anticancer Res. 2016 Oct;36(10):5215-5226. | ||||||||||
| Title: | The Significant Role of Cyclin D1 in the Synergistic Growth-inhibitory Effect of Combined Therapy of Vandetanib with 5-Fluorouracil for Gastric Cancer. | ||||||||||
| Author: | Yawata, Kazunori|Osada, Shinji|Tanahashi, Toshiyuki|Matsui, Satoshi|Sasaki, Yoshiyuki|Tanaka, Yoshihiro|Okumura, Naoki|Matsuhashi, Nobuhisa|Takahashi, Takao|Yamaguchi, Kazuya|Yoshida, Kazuhiro | ||||||||||
| PMID: | 27798882 | ||||||||||
| 71. | |||||||||||
| Journal: | Am J Transl Res. 2016 Dec 15;8(12):5729-5740. eCollection 2016. | ||||||||||
| Title: | Tumor profiling of co-regulated receptor tyrosine kinase and chemoresistant genes reveal different targeting options for lung and gastroesophageal cancers. | ||||||||||
| Author: | Wu, Jianzhong|Li, Shuchun|Ma, Rong|Sharma, Ashok|Bai, Shan|Dun, Boying|Cao, Haixia|Jing, Changwen|She, Jinxiong|Feng, Jifeng | ||||||||||
| PMID: | 28078044 | ||||||||||
| 72. | |||||||||||
| Journal: | Oncol Lett. 2016 May;11(5):3477-3482. | ||||||||||
| Title: | Evaluation of effects of thymidylate synthase and excision repair cross-complementing 1 polymorphisms on chemotherapy outcome in patients with gastrointestinal tumors using peripheral venous blood. | ||||||||||
| Author: | Huang, Kaida|Shen, Yan|Zhang, Fengqi|Wang, Shanshan|Wei, Xiao | ||||||||||
| PMID: | 27123139 | ||||||||||
| 73. | |||||||||||
| Journal: | Int J Biol Markers. 2016 May 28;31(2):e101-9. | ||||||||||
| Title: | High/positive expression of 5-fluorouracil metabolic enzymes predicts better response to S-1 in patients with gastric cancer: a meta-analysis. | ||||||||||
| Author: | Wang, Dan|Yu, Xuejun|Wang, Xiuwen | ||||||||||
| PMID: | 27012156 | ||||||||||
| 74. | |||||||||||
| Journal: | Pharmacogenomics J. 2017 Oct;17(5):441-451. | ||||||||||
| Title: | Pharmacogenetic variants associated with outcome in patients with advanced gastric cancer treated with fluoropyrimidine and platinum-based triplet combinations: a pooled analysis of three prospective studies. | ||||||||||
| Author: | Meulendijks, D|Rozeman, E A|Cats, A|Sikorska, K|Joerger, M|Deenen, M J|Beijnen, J H|Schellens, J H M | ||||||||||
| PMID: | 27995989 | ||||||||||
| 75. | |||||||||||
| Journal: | BMC Gastroenterol. 2017 Jan 5;17(1):2. | ||||||||||
| Title: | Clinical significance of UGT1A1 polymorphism and expression of ERCC1, BRCA1, TYMS, RRM1, TUBB3, STMN1 and TOP2A in gastric cancer. | ||||||||||
| Author: | Cao, Yongkuan|Zhang, Guohu|Wang, Peihong|Zhou, Jun|Gan, Wei|Song, Yaning|Huang, Ling|Zhang, Ya|Luo, Guode|Gong, Jiaqing|Zhang, Lin | ||||||||||
| PMID: | 28056823 | ||||||||||
| 76. | |||||||||||
| Journal: | Br J Cancer. 2017 Mar 28;116(7):903-911. | ||||||||||
| Title: | Inhibition of polypyrimidine tract-binding protein 3 induces apoptosis and cell cycle arrest, and enhances the cytotoxicity of 5- fluorouracil in gastric cancer cells. | ||||||||||
| Author: | Liang, Xin|Shi, Haiyang|Yang, Liyan|Qiu, Cen|Lin, Shengchao|Qi, Yingxue|Li, Jiyu|Zhao, Aiguang|Liu, Jianwen | ||||||||||
| PMID: | 28222070 | ||||||||||
| 77. | |||||||||||
| Journal: | World J Gastroenterol. 2017 Dec 28;23(48):8533-8543. | ||||||||||
| Title: | Analysis of 12 variants in the development of gastric and colorectal cancers. | ||||||||||
| Author: | Cavalcante, Giovanna C|Amador, Marcos At|Ribeiro Dos Santos, Andre M|Carvalho, Darlen C|Andrade, Roberta B|Pereira, Esdras Eb|Fernandes, Marianne R|Costa, Danielle F|Santos, Ney Pc|Assumpcao, Paulo P|Ribeiro Dos Santos, Andrea|Santos, Sidney | ||||||||||
| PMID: | 29358861 | ||||||||||
| 78. | |||||||||||
| Journal: | J Cell Biochem. 2018 Jan;119(1):1193-1203. | ||||||||||
| Title: | Metformin-induced alterations in nucleotide metabolism cause 5-fluorouracil resistance but gemcitabine susceptibility in oesophageal squamous cell carcinoma. | ||||||||||
| Author: | Mynhardt, Charissa|Damelin, Leonard H|Jivan, Rupal|Peres, Jade|Prince, Sharon|Veale, Robin B|Mavri-Damelin, Demetra | ||||||||||
| PMID: | 28722177 | ||||||||||
| 79. | |||||||||||
| Journal: | Cancer Biomark. 2018 Feb 6;21(2):439-447. | ||||||||||
| Title: | Methods and significance of the combined detection of HER2 gene amplification and chemosensitivity in gastric cancer. | ||||||||||
| Author: | Wang, Yang-Kun|Wang, Su-Nan|Li, Ying-Ying|Wang, Gong-Ping|Yun, Tian|Zhu, Chao-Ya|Yang, Bin-Feng|Li, Cong-Yang|Jiang, Bo|Zhu, Mei-Ling | ||||||||||
| PMID: | 29125480 | ||||||||||
| 80. | |||||||||||
| Journal: | Acta Biochim Pol. 2018;65(2):227-234. | ||||||||||
| Title: | TYMS 2R3R polymorphism and DPYD [IVS]14+1G>A gene mutation in Mexican colorectal cancer patients. | ||||||||||
| Author: | Gallegos-Arreola, Martha Patricia|Zuniga-Gonzalez, Guillermo Moises|Sanchez-Lopez, Josefina Yoaly|Cruz, Alondra Yeraldi Naranjo|Peralta-Leal, Valeria|Figuera, Luis Eduardo|Puebla-Perez, Ana Maria|Ronquillo-Carreon, Carlos Alberto|Puebla-Mora, Ana Graciela | ||||||||||
| PMID: | 29906295 | ||||||||||
| 81. | |||||||||||
| Journal: | Gastric Cancer. 2018 Oct 1. pii: 10.1007/s10120-018-0881-3. | ||||||||||
| Title: | The inhibition of thymidine phosphorylase can reverse acquired 5FU-resistance in gastric cancer cells. | ||||||||||
| Author: | Mori, Ryutaro|Yoshida, Kazuhiro|Futamura, Manabu|Suetsugu, Tomonari|Shizu, Kaoru|Tanahashi, Toshiyuki|Tanaka, Yoshihiro|Matsuhashi, Nobuhisha|Yamaguchi, Kazuya | ||||||||||
| PMID: | 30276573 | ||||||||||