Literatures

Primary Site >> Colorectal Cancer

Gene >> TYMP

1.
Journal:	J Biol Chem. 1995 Aug 11;270(32):19073-7.
Title:	Thymidine phosphorylase mediates the sensitivity of human colon carcinoma cells to 5-fluorouracil.
Author:	Schwartz, E L\|Baptiste, N\|Wadler, S\|Makower, D
PMID:	7642571

2.
Journal:	Cancer Res. 1995 Aug 15;55(16):3543-50.
Title:	5-Ethoxy-2'-deoxyuridine, a novel substrate for thymidine phosphorylase, potentiates the antitumor activity of 5-fluorouracil when used in combination with interferon, an inducer of thymidine phosphorylase expression.
Author:	Schwartz, E L\|Baptiste, N\|Megati, S\|Wadler, S\|Otter, B A
PMID:	7627962

3.
Journal:	J Natl Cancer Inst. 1996 Aug 21;88(16):1146-51.
Title:	Platelet-derived endothelial cell growth factor in human colon cancer angiogenesis: role of infiltrating cells.
Author:	Takahashi, Y\|Bucana, C D\|Liu, W\|Yoneda, J\|Kitadai, Y\|Cleary, K R\|Ellis, L M
PMID:	8757194

4.
Journal:	Int J Oncol. 1996 Jun;8(6):1105-11.
Title:	Differential expression of platelet-derived endothelial cell growth factor (thymidine phosphorylase) in nonpolypoid and polypoid lesions of the colon.
Author:	Saeki, T\|Takashima, S\|Hosokawa, S\|Moriwaki, S\|Nagasako, K\|Masaki, T\|Salomon, D\|Ishitsuka, H
PMID:	21544470

5.
Journal:	J Natl Cancer Inst. 1996 Aug 21;88(16):1110-7.
Title:	Clinicopathologic and prognostic significance of an angiogenic factor, thymidine phosphorylase, in human colorectal carcinoma.
Author:	Takebayashi, Y\|Akiyama, S\|Akiba, S\|Yamada, K\|Miyadera, K\|Sumizawa, T\|Yamada, Y\|Murata, F\|Aikou, T
PMID:	8757190

6.
Journal:	Cancer Lett. 1997 Nov 11;119(2):227-35.
Title:	Association of vascular endothelial growth factor expression with tumor angiogenesis, survival and thymidine phosphorylase/platelet-derived endothelial cell growth factor expression in human colorectal cancer.
Author:	Amaya, H\|Tanigawa, N\|Lu, C\|Matsumura, M\|Shimomatsuya, T\|Horiuchi, T\|Muraoka, R
PMID:	9570376

7.
Journal:	Clin Cancer Res. 1998 Feb;4(2):429-34.
Title:	Significance of platelet-derived endothelial cell growth factor in the angiogenesis of human gastric cancer.
Author:	Takahashi, Y\|Bucana, C D\|Akagi, Y\|Liu, W\|Cleary, K R\|Mai, M\|Ellis, L M
PMID:	9516932

8.
Journal:	Cancer Res. 1998 Apr 1;58(7):1551-7.
Title:	Regulation of expression of thymidine phosphorylase/platelet-derived endothelial cell growth factor in human colon carcinoma cells.
Author:	Schwartz, E L\|Wan, E\|Wang, F S\|Baptiste, N
PMID:	9537263

9.
Journal:	Cancer Lett. 1998 Jun 5;128(1):55-63.
Title:	Platelet-derived endothelial cell growth factor/thymidine phosphorylase expression correlated with tumor angiogenesis and macrophage infiltration in colorectal cancer.
Author:	Matsumura, M\|Chiba, Y\|Lu, C\|Amaya, H\|Shimomatsuya, T\|Horiuchi, T\|Muraoka, R\|Tanigawa, N
PMID:	9652793

10.
Journal:	Pathol Int. 1999 Jun;49(6):491-9.
Title:	Thymidine phosphorylase expression in human colorectal mucosa, adenoma and carcinoma: role of p53 expression.
Author:	Shomori, K\|Sakatani, T\|Goto, A\|Matsuura, T\|Kiyonari, H\|Ito, H
PMID:	10469391

11.
Journal:	Cancer Res. 1999 Oct 1;59(19):5037-40.
Title:	Thymidine phosphorylase expression is associated with both increase of intratumoral microvessels and decrease of apoptosis in human colorectal carcinomas.
Author:	Matsuura, T\|Kuratate, I\|Teramachi, K\|Osaki, M\|Fukuda, Y\|Ito, H
PMID:	10519420

12.
Journal:	Cancer. 2000 Jan 1;88(1):42-9.
Title:	Expression of platelet-derived endothelial cell growth factor correlates with good prognosis in patients with colorectal carcinoma.
Author:	Saito, S\|Tsuno, N\|Nagawa, H\|Sunami, E\|Zhengxi, J\|Osada, T\|Kitayama, J\|Shibata, Y\|Tsuruo, T\|Muto, T
PMID:	10618604

13.
Journal:	Clin Cancer Res. 2000 Apr;6(4):1322-7.
Title:	Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase.
Author:	Salonga, D\|Danenberg, K D\|Johnson, M\|Metzger, R\|Groshen, S\|Tsao-Wei, D D\|Lenz, H J\|Leichman, C G\|Leichman, L\|Diasio, R B\|Danenberg, P V
PMID:	10778957

14.
Journal:	Scand J Gastroenterol. 2000 Apr;35(4):413-8.
Title:	Tissue concentration of platelet-derived endothelial cell growth factor in colorectal cancer.
Author:	Ohi, M\|Miki, C
PMID:	10831266

15.
Journal:	Gan To Kagaku Ryoho. 2001 Oct;28(11):1519-22.
Title:	[Thymidine phosphorylase expression in hepatic metastasis from colorectal carcinoma].
Author:	Takanishi, K\|Matsumoto, J\|Minami, T
PMID:	11707969

16.
Journal:	Anticancer Res. 2001 Nov-Dec;21(6B):4349-53.
Title:	Prognostic role of angiogenesis in colorectal cancer.
Author:	Papamichael, D
PMID:	11908690

17.
Journal:	Oncogene. 2002 Dec 5;21(55):8477-85.
Title:	The Sp1 transcription factor contributes to the tumor necrosis factor-induced expression of the angiogenic factor thymidine phosphorylase in human colon carcinoma cells.
Author:	Zhu, Geng Hui\|Lenzi, Michelle\|Schwartz, Edward L
PMID:	12466967

18.
Journal:	Oncology. 2003;64(1):61-73.
Title:	Clinical significance of angiogenic factor expression at the deepest invasive site of advanced colorectal carcinoma.
Author:	Kaio, Eijiro\|Tanaka, Shinji\|Kitadai, Yasuhiko\|Sumii, Masaharu\|Yoshihara, Masaharu\|Haruma, Ken\|Chayama, Kazuaki
PMID:	12457033

19.
Journal:	Oncol Rep. 2003 Jan-Feb;10(1):9-13.
Title:	The angiogenic switch of human colon cancer occurs simultaneous to initiation of invasion.
Author:	Takahashi, Yutaka\|Ellis, Lee M\|Mai, Masayoshi
PMID:	12469136

20.
Journal:	Biochem Biophys Res Commun. 2003 Feb 14;301(3):675-9.
Title:	Rapid disappearance of deoxyribose-1-phosphate in platelet derived endothelial cell growth factor/thymidine phosphorylase overexpressing cells.
Author:	de Bruin, M\|Smid, K\|Laan, A C\|Noordhuis, P\|Fukushima, M\|Hoekman, K\|Pinedo, H M\|Peters, G J
PMID:	12565833

21.
Journal:	Int J Oncol. 2003 Apr;22(4):835-41.
Title:	Effects of introduction of dThdPase cDNA on sensitivity to 5'-deoxy-5-fluorouridine and tumor angiogenesis.
Author:	Kim, Ryungsa\|Murakami, Shigeru\|Toge, Tetsuya
PMID:	12632076

22.
Journal:	J Gastroenterol. 2003;38(3):229-37.
Title:	Expression of platelet-derived endothelial cell growth factor in inflammatory bowel disease.
Author:	Saito, Shinsuke\|Tsuno, Nelson H\|Sunami, Eiji\|Hori, Nobukazu\|Kitayama, Joji\|Kazama, Shinsuke\|Okaji, Yurai\|Kawai, Kazushige\|Kanazawa, Takamitsu\|Watanabe, Toshiaki\|Shibata, Yoichi\|Nagawa, Hirokazu
PMID:	12673445

23.
Journal:	Ann Surg Oncol. 2003 Jun;10(5):582-7.
Title:	Platelet-derived endothelial cell growth factor mediates Rho-associated coiled-coil domain kinase messenger RNA expression and promotes cell motility.
Author:	Yoshinaga, Keiji\|Inoue, Hiroshi\|Tanaka, Fumiaki\|Mimori, Koshi\|Utsunomiya, Tohru\|Mori, Masaki
PMID:	12794027

24.
Journal:	Eur J Surg Oncol. 2004 Apr;30(3):296-302.
Title:	Platelet-derived endothelial cell growth factor expression is an independent prognostic factor in colorectal cancer patients after curative surgery.
Author:	Tsuji, T\|Sawai, T\|Yamashita, H\|Takeshita, H\|Nakagoe, T\|Shindou, H\|Fukuoka, H\|Yoshinaga, M\|Hidaka, S\|Yasutake, T\|Nagayasu, T\|Tagawa, Y
PMID:	15028312

25.
Journal:	Zhonghua Zhong Liu Za Zhi. 2004 May;26(5):297-9.
Title:	[Expression of thymidine phosphorylase in cancer].
Author:	Jiang, Li-na\|Yu, Shi-ying\|Xiong, Hui-hua\|Zhang, Meng-xian
PMID:	15312368

26.
Journal:	Am J Surg Pathol. 2005 Oct;29(10):1304-9.
Title:	Immunohistochemical analysis of thymidylate synthase, thymidine phosphorylase, and dihydropyrimidine dehydrogenase in rectal cancer (cUICC II/III): correlation with histopathologic tumor regression after 5-fluorouracil-based long-term neoadjuvant chemorad
Author:	Jakob, Christiane\|Liersch, Torsten\|Meyer, Wolfdietrich\|Baretton, Gustavo B\|Hausler, Peter\|Schwabe, Wolfgang\|Becker, Heinz\|Aust, Daniela E
PMID:	16160472

27.
Journal:	Br J Cancer. 2005 Jan 31;92(2):259-64.
Title:	Unfavourable expression of pharmacologic markers in mucinous colorectal cancer.
Author:	Glasgow, S C\|Yu, J\|Carvalho, L P\|Shannon, W D\|Fleshman, J W\|McLeod, H L
PMID:	15655543

28.
Journal:	Anticancer Drugs. 2005 Mar;16(3):285-92.
Title:	Determinants of trifluorothymidine sensitivity and metabolism in colon and lung cancer cells.
Author:	Temmink, Olaf H\|de Bruin, Michiel\|Comijn, Elizabeth M\|Fukushima, Masakazu\|Peters, Godefridus J
PMID:	15711180

29.
Journal:	Am J Surg Pathol. 2006 Sep;30(9):1169-74.
Title:	Prognostic value of histologic tumor regression, thymidylate synthase, thymidine phosphorylase, and dihydropyrimidine dehydrogenase in rectal cancer UICC Stage II/III after neoadjuvant chemoradiotherapy.
Author:	Jakob, Christiane\|Liersch, Torsten\|Meyer, Wolfdietrich\|Baretton, Gustavo B\|Schwabe, Wolfgang\|Hausler, Peter\|Kulle, Bettina\|Becker, Heinz\|Aust, Daniela E
PMID:	16931962

30.
Journal:	Br J Cancer. 2007 Jan 15;96(1):61-6. Epub 2006 Dec 19.
Title:	The Hollow Fibre Assay as a model for in vivo pharmacodynamics of fluoropyrimidines in colon cancer cells.
Author:	Temmink, O H\|Prins, H-J\|van Gelderop, E\|Peters, G J
PMID:	17179993

31.
Journal:	Cancer Lett. 2007 Nov 8;257(1):73-8. Epub 2007 Aug 7.
Title:	Angiogenic effect of naive and 5-fluorouracil resistant colon carcinoma on endothelial cells in vitro.
Author:	Schonau, Kristina K\|Steger, Gunther G\|Mader, Robert M
PMID:	17686575

32.
Journal:	Pak J Biol Sci. 2007 Oct 1;10(19):3350-5.
Title:	Association between p53 expression and Bcl-2, P-glycoprotein, topoisomerase II alpha, thymidylate synthase and thymidine phosphorylase as potential therapeutic targets in colorectal cancer patients.
Author:	Bidgoli, Sepideh Arbabi\|Azizi, Ebrahim\|Zavarhei, Mansour Djamali
PMID:	19090149

33.
Journal:	Clin Cancer Res. 2008 Apr 1;14(7):2065-74.
Title:	Neoadjuvant treatment of colorectal cancer with bevacizumab: the perioperative angiogenic balance is sensitive to systemic thrombospondin-1 levels.
Author:	Brostjan, Christine\|Gebhardt, Kristina\|Gruenberger, Birgit\|Steinrueck, Verena\|Zommer, Halina\|Freudenthaler, Harald\|Roka, Sebastian\|Gruenberger, Thomas
PMID:	18381946

34.
Journal:	Hepatogastroenterology. 2008 Nov-Dec;55(88):2045-8.
Title:	Significance of thymidine phosphorylase expression in stromal cells around invasive front of rectal cancer.
Author:	Kobayashi, Tetsuya\|Kawahara, Hidejiro\|Koido, Shigeo\|Kobayashi, Susumu\|Kashiwagi, Hideyuki\|Yanaga, Katsuhiko
PMID:	19260474

35.
Journal:	Med Res Rev. 2009 Nov;29(6):903-53.
Title:	The dual role of thymidine phosphorylase in cancer development and chemotherapy.
Author:	Bronckaers, Annelies\|Gago, Federico\|Balzarini, Jan\|Liekens, Sandra
PMID:	19434693

36.
Journal:	Eur J Cancer. 2009 Jul;45(11):1935-49.
Title:	A review on the use of molecular markers of cytotoxic therapy for colorectal cancer, what have we learned?
Author:	Koopman, Miriam\|Venderbosch, Sabine\|Nagtegaal, Iris D\|van Krieken, Johan H\|Punt, Cornelis J
PMID:	19473832

37.
Journal:	Cancer Chemother Pharmacol. 2010 Nov;66(6):1167-71.
Title:	Value of gene polymorphisms as markers of 5-FU therapy response in stage III colon carcinoma: a pilot study.
Author:	Farina-Sarasqueta, Arantza\|van Lijnschoten, Gesina\|Rutten, Harm J T\|van den Brule, Adriaan J C
PMID:	20665215

38.
Journal:	Eur J Cancer. 2010 Dec;46(18):3358-64.
Title:	Amplification of thymidylate synthetase in metastatic colorectal cancer patients pretreated with 5-fluorouracil-based chemotherapy.
Author:	Watson, Roshawn G\|Muhale, Filipe\|Thorne, Leigh B\|Yu, Jinsheng\|O'Neil, Bert H\|Hoskins, Janelle M\|Meyers, Michael O\|Deal, Allison M\|Ibrahim, Joseph G\|Hudson, Michael L\|Walko, Christine M\|McLeod, Howard L\|Auman, James T
PMID:	20727737

39.
Journal:	Nucleosides Nucleotides Nucleic Acids. 2011 Dec;30(12):1197-202.
Title:	Deoxyribose protects against rapamycin-induced cytotoxicity in colorectal cancer cells in vitro.
Author:	Bijnsdorp, I V\|Peters, G J
PMID:	22132975

40.
Journal:	Clin Med Insights Oncol. 2012;6:347-53.
Title:	Thymidine Phosphorylase Gene Expression in Stage III Colorectal Cancer.
Author:	Lindskog, Elinor B\|Wettergren, Yvonne\|Odin, Elisabeth\|Gustavsson, Bengt\|Derwinger, Kristoffer
PMID:	23115484

41.
Journal:	In Vivo. 2012 Nov-Dec;26(6):1057-67.
Title:	Predictive role of thymidine phosphorylase expression in patients with colorectal cancer and its association with angiogenesis-related proteins and extracellular matrix components.
Author:	Mitselou, Antigony\|Ioachim, Elli\|Skoufi, Urania\|Tsironis, Christos\|Tsimogiannis, Konstantinos E\|Skoufi, Christina\|Vougiouklakis, Theodoros\|Briasoulis, Evagelos
PMID:	23160694

42.
Journal:	Anticancer Res. 2012 May;32(5):1757-62.
Title:	Expression levels of thymidylate synthase, dihydropyrimidine dehydrogenase, and thymidine phosphorylase in patients with colorectal cancer.
Author:	Goto, Tetsuhiro\|Shinmura, Kazuki\|Yokomizo, Kazuaki\|Sakuraba, Kazuma\|Kitamura, Youhei\|Shirahata, Atsushi\|Saito, Mitsuo\|Kigawa, Gaku\|Nemoto, Hiroshi\|Sanada, Yutaka\|Hibi, Kenji
PMID:	22593457

43.
Journal:	Anticancer Res. 2013 Jun;33(6):2447-51.
Title:	Changes in thymidine phosphorylase gene expression related to treatment of rectal cancer.
Author:	Derwinger, Kristoffer\|Lindskog, Elinor Bexe\|Palmqvist, Erik\|Wettergren, Yvonne
PMID:	23749894

44.
Journal:	Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2013 Jun;25(3):250-4.
Title:	[Expression of vascular growth factors in intestinal tissues in colorectal carcinoma patients with schistosomiasis japonica].
Author:	Ruan, Shui-Liang\|Wang, Bo\|Lu, Qi-Ming\|Dong, Lai-Rong\|Cao, Chen-Xi\|Xu, Shui-Ling\|Shen, Wen-Yan
PMID:	24024441

45.
Journal:	PLoS One. 2013 Oct 22;8(10):e78053.
Title:	Evaluating predictive pharmacogenetic signatures of adverse events in colorectal cancer patients treated with fluoropyrimidines.
Author:	Jennings, Barbara A\|Loke, Yoon K\|Skinner, Jane\|Keane, Melanie\|Chu, Gavin S\|Turner, Richard\|Epurescu, Daniel\|Barrett, Ann\|Willis, Gavin
PMID:	24167597

46.
Journal:	Anticancer Res. 2014 Sep;34(9):4949-62.
Title:	Prognostic markers in early-stage colorectal cancer: significance of TYMS mRNA expression.
Author:	Koumarianou, Anna\|Tzeveleki, Ioanna\|Mekras, Dimosthenis\|Eleftheraki, Anastasia G\|Bobos, Mattheos\|Wirtz, Ralph\|Fountzilas, Elena\|Valavanis, Christos\|Xanthakis, Ioannis\|Kalogeras, Konstantine T\|Basdanis, George\|Pentheroudakis, George\|Kotoula, Vassiliki\|Foun
PMID:	25202077

47.
Journal:	Clin Transl Oncol. 2015 Apr;17(4):322-9.
Title:	Gene expression differences in primary colorectal tumors and matched liver metastases: chemotherapy related or tumoral heterogeneity?
Author:	Lopez-Gomez, M\|Moreno-Rubio, J\|Suarez-Garcia, I\|Cejas, P\|Madero, R\|Casado, E\|Jimenez, A M\|Sereno, M\|Gomez-Raposo, C\|Zambrana, F\|Merino, M\|Fernandez-Luengas, D\|Feliu, J
PMID:	25301403

48.
Journal:	Am J Clin Oncol. 2016 Jun;39(3):236-42.
Title:	Phase II Trial of Target-guided Personalized Chemotherapy in First-line Metastatic Colorectal Cancer.
Author:	Cubillo, Antonio\|Rodriguez-Pascual, Jesus\|Lopez-Rios, Fernando\|Plaza, Carlos\|Garcia, Elena\|Alvarez, Rafael\|de Vicente, Emilio\|Quijano, Yolanda\|Hernando, Ovidio\|Rubio, Carmen\|Perea, Sofia\|Sanchez, Gema\|Hidalgo, Manuel
PMID:	24517959

49.
Journal:	Int J Mol Med. 2016 Feb;37(2):319-28.
Title:	Association between mRNA expression of chemotherapy-related genes and clinicopathological features in colorectal cancer: A large-scale population analysis.
Author:	Shimamoto, Yuji\|Nukatsuka, Mamoru\|Takechi, Teiji\|Fukushima, Masakazu
PMID:	26676887

50.
Journal:	Anticancer Res. 2016 May;36(5):2433-40.
Title:	Increase in Gene Expression of TYMP, DPYD and HIF1A Are Associated with Response to Preoperative Chemoradiotherapy Including S-1 or UFT for Rectal Cancer.
Author:	Sadahiro, Sotaro\|Suzuki, Toshiyuki\|Tanaka, Akira\|Okada, Kazutake\|Saito, Gota\|Kamijo, Akemi\|Nagase, Hideki
PMID:	27127154

51.
Journal:	Visc Med. 2016 Jun;32(3):206-10.
Title:	Effects of Platelet-Derived Endothelial Cell Growth Factor and Doppler Perfusion Index in Patients with Colorectal Hepatic Metastases.
Author:	Jiang, Xueming\|Zhang, Zhixiang\|Zhao, Na\|He, Xianghui\|Guo, Hao
PMID:	27493949

52.
Journal:	Pharmacol Res. 2017 Jun;120:133-137.
Title:	Identification of new SNPs associated with severe toxicity to capecitabine.
Author:	Pellicer, Marta\|Garcia-Gonzalez, Xandra\|Garcia, Maria I\|Robles, Luis\|Gravalos, Cristina\|Garcia-Alfonso, Pilar\|Pachon, Vanessa\|Longo, Federico\|Martinez, Virginia\|Blanco, Carolina\|Iglesias, Irene\|Sanjurjo, Maria\|Lopez-Fernandez, Luis A
PMID:	28347776

53.
Journal:	Future Oncol. 2018 May;14(12):1223-1231.
Title:	Thymidine phosphorylase: the unforeseen driver in colorectal cancer treatment?
Author:	Tampellini, Marco\|Bironzo, Paolo\|Di Maio, Massimo\|Scagliotti, Giorgio V
PMID:	29701074

54.
Journal:	Zhonghua Yi Xue Za Zhi. 2018 Aug 28;98(32):2569-2573.
Title:	[The influence of Thymidine Phosphorylase genetic variation on clinical outcomes and safety of colorectal cancer patients received adjuvant chemotherapy after R0 resection].
Author:	Du, Y B\|Zhang, T F\|Cui, K\|Jin, S L\|Xi, Y\|Ma, W
PMID:	30220141