Primary Site >> Colorectal Cancer
Gene >> TXN
| 1. | |||||||||||
| Journal: | Biochim Biophys Acta. 1994 Aug 2;1218(3):292-6. | ||||||||||
| Title: | The predicted amino acid sequence of human thioredoxin is identical to that of the autocrine growth factor human adult T-cell derived factor (ADF): thioredoxin mRNA is elevated in some human tumors. | ||||||||||
| Author: | Gasdaska, P Y|Oblong, J E|Cotgreave, I A|Powis, G | ||||||||||
| PMID: | 8049254 | ||||||||||
| 2. | |||||||||||
| Journal: | Clin Cancer Res. 1996 Feb;2(2):427-32. | ||||||||||
| Title: | Increased expression of thioredoxin/adult T-cell leukemia-derived factor in cisplatin-resistant human cancer cell lines. | ||||||||||
| Author: | Yamada, M|Tomida, A|Yoshikawa, H|Taketani, Y|Tsuruo, T | ||||||||||
| PMID: | 9816187 | ||||||||||
| 3. | |||||||||||
| Journal: | Cancer Res. 1997 Nov 1;57(21):4965-70. | ||||||||||
| Title: | Mechanisms of the regulation of thioredoxin reductase activity in cancer cells by the chemopreventive agent selenium. | ||||||||||
| Author: | Gallegos, A|Berggren, M|Gasdaska, J R|Powis, G | ||||||||||
| PMID: | 9354464 | ||||||||||
| 4. | |||||||||||
| Journal: | Cancer Chemother Pharmacol. 1997;40(1):31-7. | ||||||||||
| Title: | Overexpression of thioredoxin does not confer resistance to cisplatin in transfected human ovarian and colon cancer cell lines. | ||||||||||
| Author: | Yamada, M|Tomida, A|Yoshikawa, H|Taketani, Y|Tsuruo, T | ||||||||||
| PMID: | 9137526 | ||||||||||
| 5. | |||||||||||
| Journal: | Hum Pathol. 2000 Apr;31(4):475-81. | ||||||||||
| Title: | Thioredoxin, a putative oncogene product, is overexpressed in gastric carcinoma and associated with increased proliferation and increased cell survival. | ||||||||||
| Author: | Grogan, T M|Fenoglio-Prieser, C|Zeheb, R|Bellamy, W|Frutiger, Y|Vela, E|Stemmerman, G|Macdonald, J|Richter, L|Gallegos, A|Powis, G | ||||||||||
| PMID: | 10821495 | ||||||||||
| 6. | |||||||||||
| Journal: | Oncol Rep. 2002 Jan-Feb;9(1):75-9. | ||||||||||
| Title: | Up-regulation of vitamin D3 up-regulated protein 1 gene in response to 5-fluorouracil in colon carcinoma SW620. | ||||||||||
| Author: | Takahashi, Yasuo|Nagata, Toshihito|Ishii, Yukimoto|Ikarashi, Masahito|Ishikawa, Koichi|Asai, Satoshi | ||||||||||
| PMID: | 11748459 | ||||||||||
| 7. | |||||||||||
| Journal: | Cancer Res. 2002 Sep 1;62(17):5089-95. | ||||||||||
| Title: | The redox protein thioredoxin-1 (Trx-1) increases hypoxia-inducible factor 1alpha protein expression: Trx-1 overexpression results in increased vascular endothelial growth factor production and enhanced tumor angiogenesis. | ||||||||||
| Author: | Welsh, Sarah J|Bellamy, William T|Briehl, Margaret M|Powis, Garth | ||||||||||
| PMID: | 12208766 | ||||||||||
| 8. | |||||||||||
| Journal: | Am J Physiol Gastrointest Liver Physiol. 2002 Dec;283(6):G1352-9. | ||||||||||
| Title: | Glutathione and thioredoxin redox during differentiation in human colon epithelial (Caco-2) cells. | ||||||||||
| Author: | Nkabyo, Yvonne S|Ziegler, Thomas R|Gu, Li H|Watson, Walter H|Jones, Dean P | ||||||||||
| PMID: | 12433666 | ||||||||||
| 9. | |||||||||||
| Journal: | Lab Invest. 2003 Sep;83(9):1321-31. | ||||||||||
| Title: | Thioredoxin reductase 1 expression in colon cancer: discrepancy between in vitro and in vivo findings. | ||||||||||
| Author: | Lechner, Sandra|Muller-Ladner, Ulf|Neumann, Elena|Spottl, Tanja|Schlottmann, Klaus|Ruschoff, Josef|Scholmerich, Jurgen|Kullmann, Frank | ||||||||||
| PMID: | 13679440 | ||||||||||
| 10. | |||||||||||
| Journal: | Anticancer Res. 2003 May-Jun;23(3B):2425-33. | ||||||||||
| Title: | The thioredoxin-thioredoxin reductase system: over-expression in human cancer. | ||||||||||
| Author: | Lincoln, David T|Ali Emadi, Eman M|Tonissen, Kathryn F|Clarke, Frank M | ||||||||||
| PMID: | 12894524 | ||||||||||
| 11. | |||||||||||
| Journal: | Mol Cancer Ther. 2003 Mar;2(3):235-43. | ||||||||||
| Title: | The thioredoxin redox inhibitors 1-methylpropyl 2-imidazolyl disulfide and pleurotin inhibit hypoxia-induced factor 1alpha and vascular endothelial growth factor formation. | ||||||||||
| Author: | Welsh, Sarah J|Williams, Ryan R|Birmingham, Anne|Newman, David J|Kirkpatrick, D Lynn|Powis, Garth | ||||||||||
| PMID: | 12657718 | ||||||||||
| 12. | |||||||||||
| Journal: | Di Yi Jun Yi Da Xue Xue Bao. 2005 Oct;25(10):1221-4. | ||||||||||
| Title: | [PCR amplification, cloning and protein expression of interferon-inducible transmembrane protein-1 gene]. | ||||||||||
| Author: | Liu, Yu-hu|Zhong, Dong|Liu, Juan|Zhang, Zhen-shu|Chen, Cun-long|Wu, Jin-bao|Xiao, Bing|Guo, Wen-ying | ||||||||||
| PMID: | 16234093 | ||||||||||
| 13. | |||||||||||
| Journal: | Anticancer Drugs. 2006 Jun;17(5):539-44. | ||||||||||
| Title: | Thioredoxin reductase and cancer cell growth inhibition by organogold(III) compounds. | ||||||||||
| Author: | Engman, Lars|McNaughton, Michael|Gajewska, Malgorzata|Kumar, Sangit|Birmingham, Anne|Powis, Garth | ||||||||||
| PMID: | 16702810 | ||||||||||
| 14. | |||||||||||
| Journal: | Br J Pharmacol. 2007 Aug;151(8):1167-75. | ||||||||||
| Title: | A cellular and molecular investigation of the action of PMX464, a putative thioredoxin inhibitor, in normal and colorectal cancer cell lines. | ||||||||||
| Author: | Mukherjee, A|Huber, K|Evans, H|Lakhani, N|Martin, S | ||||||||||
| PMID: | 17572693 | ||||||||||
| 15. | |||||||||||
| Journal: | Hum Pathol. 2008 Feb;39(2):201-8. | ||||||||||
| Title: | Increased expression of thioredoxin-1, vascular endothelial growth factor, and redox factor-1 is associated with poor prognosis in patients with liver metastasis from colorectal cancer. | ||||||||||
| Author: | Noike, Terumasa|Miwa, Shiro|Soeda, Junpei|Kobayashi, Akira|Miyagawa, Shin-ichi | ||||||||||
| PMID: | 17949784 | ||||||||||
| 16. | |||||||||||
| Journal: | Bioorg Med Chem Lett. 2008 Jun 15;18(12):3526-31. | ||||||||||
| Title: | Cycloalkyl-substituted aryl chloroethylureas inhibiting cell cycle progression in G0/G1 phase and thioredoxin-1 nuclear translocation. | ||||||||||
| Author: | Fortin, Jessica S|Cote, Marie-France|Lacroix, Jacques|Patenaude, Alexandre|Petitclerc, Eric|C-Gaudreault, Rene | ||||||||||
| PMID: | 18502639 | ||||||||||
| 17. | |||||||||||
| Journal: | Cancer Res. 2008 Oct 15;68(20):8269-77. | ||||||||||
| Title: | The thioredoxin system mediates redox-induced cell death in human colon cancer cells: implications for the mechanism of action of anticancer agents. | ||||||||||
| Author: | Sun, Yu|Rigas, Basil | ||||||||||
| PMID: | 18922898 | ||||||||||
| 18. | |||||||||||
| Journal: | Cancer Epidemiol. 2009 Oct;33(3-4):281-7. | ||||||||||
| Title: | Preferential overexpression of glutaredoxin3 in human colon and lung carcinoma. | ||||||||||
| Author: | Cha, Mee-Kyung|Kim, Il-Han | ||||||||||
| PMID: | 19797004 | ||||||||||
| 19. | |||||||||||
| Journal: | Dis Colon Rectum. 2010 Dec;53(12):1624-31. | ||||||||||
| Title: | Is local excision after complete pathological response to neoadjuvant chemoradiation for rectal cancer an acceptable treatment option? | ||||||||||
| Author: | Kundel, Yulia|Brenner, Ronen|Purim, Ofer|Peled, Nir|Idelevich, Efraim|Fenig, Eyal|Sulkes, Aaron|Brenner, Baruch | ||||||||||
| PMID: | 21178856 | ||||||||||
| 20. | |||||||||||
| Journal: | Rev Prat. 2010 Oct 20;60(8):1089-93. | ||||||||||
| Title: | [Operable colon cancer: initial strategy]. | ||||||||||
| Author: | Andre, Thierry|Tuvignon, Noshine|Taieb, Julien|Vaillant, Jean-Christophe|Hannoun, Laurent|de Gramont, Aimery | ||||||||||
| PMID: | 21197740 | ||||||||||
| 21. | |||||||||||
| Journal: | Invest New Drugs. 2012 Aug;30(4):1591-6. | ||||||||||
| Title: | A phase I trial of PX-12, a small-molecule inhibitor of thioredoxin-1, administered as a 72-hour infusion every 21 days in patients with advanced cancers refractory to standard therapy. | ||||||||||
| Author: | Ramanathan, Ramesh K|Stephenson, Joe J|Weiss, Glen J|Pestano, Linda A|Lowe, Ann|Hiscox, Alton|Leos, Rafael A|Martin, Julie C|Kirkpatrick, Lynn|Richards, Donald A | ||||||||||
| PMID: | 21863237 | ||||||||||
| 22. | |||||||||||
| Journal: | Biochem Cell Biol. 2012 Apr;90(2):173-8. | ||||||||||
| Title: | Changes in the levels of thioredoxin and indoleamine-2,3-dioxygenase activity in plasma of patients with colorectal cancer treated with chemotherapy. | ||||||||||
| Author: | Cavia-Saiz, Monica|Muniz, Pilar|De Santiago, Reyes|Herreros-Villanueva, Marta|Garcia-Giron, Carlos|Lopez, Ana Sofia|Coma-Del Corral, Maria Jesus | ||||||||||
| PMID: | 22257103 | ||||||||||
| 23. | |||||||||||
| Journal: | Biomed Chromatogr. 2013 Apr;27(4):440-50. | ||||||||||
| Title: | Comprehensive fluorogenic derivatization-liquid chromatography/tandem mass spectrometry proteomic analysis of colorectal cancer cell to identify biomarker candidate. | ||||||||||
| Author: | Koshiyama, Akiyo|Ichibangase, Tomoko|Imai, Kazuhiro | ||||||||||
| PMID: | 22991145 | ||||||||||
| 24. | |||||||||||
| Journal: | Antioxid Redox Signal. 2013 Sep 20;19(9):899-911. | ||||||||||
| Title: | Thioredoxin-like protein 2 is overexpressed in colon cancer and promotes cancer cell metastasis by interaction with ran. | ||||||||||
| Author: | Lu, Yuanyuan|Zhao, Xiaodi|Li, Kai|Luo, Guanhong|Nie, Yongzhan|Shi, Yongquan|Zhou, Yi|Ren, Gui|Feng, Bin|Liu, Zhenxiong|Pan, Yan|Li, Ting|Guo, Xuegang|Wu, Kaichun|Miranda-Vizuete, Antonio|Wang, Xin|Fan, Daiming | ||||||||||
| PMID: | 23311631 | ||||||||||
| 25. | |||||||||||
| Journal: | Expert Opin Ther Targets. 2013 Nov;17(11):1369-79. | ||||||||||
| Title: | Type 3 deiodinase and solid tumors: an intriguing pair. | ||||||||||
| Author: | Dentice, Monica|Antonini, Dario|Salvatore, Domenico | ||||||||||
| PMID: | 23991650 | ||||||||||
| 26. | |||||||||||
| Journal: | Int J Immunopathol Pharmacol. 2014 Apr-Jun;27(2):169-83. | ||||||||||
| Title: | Expression of thioredoxins and glutaredoxins in human hepatocellular carcinoma: correlation to cell proliferation, tumor size and metabolic syndrome. | ||||||||||
| Author: | Mollbrink, A|Jawad, R|Vlamis-Gardikas, A|Edenvik, P|Isaksson, B|Danielsson, O|Stal, P|Fernandes, A P | ||||||||||
| PMID: | 25004829 | ||||||||||
| 27. | |||||||||||
| Journal: | J Agric Food Chem. 2014 Mar 19;62(11):2353-63. | ||||||||||
| Title: | Secretome profiling reveals the signaling molecules of apoptotic HCT116 cells induced by the dietary polyacetylene gymnasterkoreayne B. | ||||||||||
| Author: | Kang, Kyungsu|Song, Dae-Geun|Lee, Eun Ha|Lee, Kyung-Mi|Park, Young Gyun|Jung, Sang Hoon|Pan, Cheol-Ho|Nho, Chu Won | ||||||||||
| PMID: | 24571669 | ||||||||||
| 28. | |||||||||||
| Journal: | Biochim Biophys Acta. 2014 Mar;1840(3):1135-44. | ||||||||||
| Title: | Powerful tumor cell growth-inhibiting activity of a synthetic derivative of atractyligenin: involvement of PI3K/Akt pathway and thioredoxin system. | ||||||||||
| Author: | Cotugno, Roberta|Gallotta, Dario|Piaz, Fabrizio Dal|Apicella, Ivana|De Falco, Sandro|Rosselli, Sergio|Bruno, Maurizio|Belisario, Maria Antonietta | ||||||||||
| PMID: | 24321480 | ||||||||||
| 29. | |||||||||||
| Journal: | Oncol Rep. 2015 Feb;33(2):967-73. | ||||||||||
| Title: | Thioredoxin-1 inhibitor, 1-methylpropyl 2-imidazolyl disulfide, inhibits the growth, migration and invasion of colorectal cancer cell lines. | ||||||||||
| Author: | Wang, Fule|Lin, Feiyan|Zhang, Peili|Ni, Wuhua|Bi, Laixi|Wu, Jianbo|Jiang, Lei | ||||||||||
| PMID: | 25483731 | ||||||||||
| 30. | |||||||||||
| Journal: | Cancer Lett. 2015 Jul 28;363(2):119-26. | ||||||||||
| Title: | Thioredoxin-like protein 2b facilitates colon cancer cell proliferation and inhibits apoptosis via NF-kappaB pathway. | ||||||||||
| Author: | Lu, Yuanyuan|Zhao, Xiaodi|Luo, Guanhong|Shen, Gaofei|Li, Kai|Ren, Gui|Pan, Yan|Wang, Xin|Fan, Daiming | ||||||||||
| PMID: | 25555669 | ||||||||||
| 31. | |||||||||||
| Journal: | Redox Biol. 2015 Aug;5:319-27. | ||||||||||
| Title: | Disruption of thioredoxin metabolism enhances the toxicity of transforming growth factor beta-activated kinase 1 (TAK1) inhibition in KRAS-mutated colon cancer cells. | ||||||||||
| Author: | Hrabe, Jennifer E|O'Leary, Brianne R|Fath, Melissa A|Rodman, Samuel N|Button, Anna M|Domann, Frederick E|Spitz, Douglas R|Mezhir, James J | ||||||||||
| PMID: | 26114584 | ||||||||||
| 32. | |||||||||||
| Journal: | Oncotarget. 2016 Mar 1;7(9):10578-93. | ||||||||||
| Title: | Heterogenous ribonucleoprotein A18 (hnRNP A18) promotes tumor growth by increasing protein translation of selected transcripts in cancer cells. | ||||||||||
| Author: | Chang, Elizabeth T|Parekh, Palak R|Yang, Qingyuan|Nguyen, Duc M|Carrier, France | ||||||||||
| PMID: | 26824423 | ||||||||||
| 33. | |||||||||||
| Journal: | Oncotarget. 2016 Sep 20;7(38):62559-62571. | ||||||||||
| Title: | Mechanism of suppressors of cytokine signaling 1 inhibition of epithelial-mesenchymal transition signaling through ROS regulation in colon cancer cells: suppression of Src leading to thioredoxin up-regulation. | ||||||||||
| Author: | Jung, Sung-Hoon|Kim, Su-Min|Lee, Choong-Eun | ||||||||||
| PMID: | 27613835 | ||||||||||
| 34. | |||||||||||
| Journal: | J Biol Chem. 2017 Jun 2;292(22):9136-9149. | ||||||||||
| Title: | Physical interaction between human ribonucleotide reductase large subunit and thioredoxin increases colorectal cancer malignancy. | ||||||||||
| Author: | Lou, Meng|Liu, Qian|Ren, Guoping|Zeng, Jiling|Xiang, Xueping|Ding, Yongfeng|Lin, Qinghui|Zhong, Tingting|Liu, Xia|Zhu, Lijun|Qi, Hongyan|Shen, Jing|Li, Haoran|Shao, Jimin | ||||||||||
| PMID: | 28411237 | ||||||||||
| 35. | |||||||||||
| Journal: | J Cell Mol Med. 2018 Apr;22(4):2430-2441. | ||||||||||
| Title: | Interplay between Trx-1 and S100P promotes colorectal cancer cell epithelial-mesenchymal transition by up-regulating S100A4 through AKT activation. | ||||||||||
| Author: | Zuo, Zhigui|Zhang, Peili|Lin, Feiyan|Shang, Wenjing|Bi, Ruichun|Lu, Fengying|Wu, Jianbo|Jiang, Lei | ||||||||||
| PMID: | 29383839 | ||||||||||
| 36. | |||||||||||
| Journal: | Oncol Lett. 2018 Feb;15(2):2364-2372. | ||||||||||
| Title: | Peroxiredoxin 1 expression in active ulcerative colitis mucosa identified by proteome analysis and involvement of thioredoxin based on immunohistochemistry. | ||||||||||
| Author: | Horie, Kayo|Mikami, Tetuo|Yoshida, Tsutomu|Sato, Yuichi|Okayasu, Isao | ||||||||||
| PMID: | 29434945 | ||||||||||