Primary Site >> Colorectal Cancer
Gene >> TSC2
| 1. | |||||||||||
| Journal: | Hum Mutat. 2003 Feb;21(2):112-5. | ||||||||||
| Title: | Characterizing mutations in samples with low-level mosaicism by collection and analysis of DHPLC fractionated heteroduplexes. | ||||||||||
| Author: | Emmerson, Paul|Maynard, Julie|Jones, Sian|Butler, Rachel|Sampson, Julian R|Cheadle, Jeremy P | ||||||||||
| PMID: | 12552557 | ||||||||||
| 2. | |||||||||||
| Journal: | Pathol Int. 2006 Jan;56(1):46-50. | ||||||||||
| Title: | Malignant perivascular epithelioid cell tumor of the colon: report of a case with molecular analysis. | ||||||||||
| Author: | Yamamoto, Hidetaka|Oda, Yoshinao|Yao, Takashi|Oiwa, Toshio|Kobayashi, Chikashi|Tamiya, Sadafumi|Kawaguchi, Ken-ichi|Hino, Okio|Tsuneyoshi, Masazumi | ||||||||||
| PMID: | 16398680 | ||||||||||
| 3. | |||||||||||
| Journal: | Int J Oncol. 2007 May;30(5):1099-107. | ||||||||||
| Title: | Genomic and transcriptomic prognostic factors in R0 Dukes B and C colorectal cancer patients. | ||||||||||
| Author: | Vendrell, Elisenda|Ribas, Maria|Valls, Joan|Sole, Xavier|Grau, Monica|Moreno, Victor|Capella, Gabriel|Peinado, Miguel A | ||||||||||
| PMID: | 17390011 | ||||||||||
| 4. | |||||||||||
| Journal: | Cancer Res. 2007 Aug 1;67(15):7106-12. | ||||||||||
| Title: | Identification of S664 TSC2 phosphorylation as a marker for extracellular signal-regulated kinase mediated mTOR activation in tuberous sclerosis and human cancer. | ||||||||||
| Author: | Ma, Li|Teruya-Feldstein, Julie|Bonner, Pauline|Bernardi, Rosa|Franz, David Neal|Witte, David|Cordon-Cardo, Carlos|Pandolfi, Pier Paolo | ||||||||||
| PMID: | 17671177 | ||||||||||
| 5. | |||||||||||
| Journal: | J Biol Chem. 2010 Aug 6;285(32):24987-98. | ||||||||||
| Title: | Tuberous sclerosis complex 2 (TSC2) regulates cell migration and polarity through activation of CDC42 and RAC1. | ||||||||||
| Author: | Larson, Yan|Liu, Jianyu|Stevens, Payton D|Li, Xin|Li, Jing|Evers, B Mark|Gao, Tianyan | ||||||||||
| PMID: | 20530489 | ||||||||||
| 6. | |||||||||||
| Journal: | Carcinogenesis. 2010 Sep;31(9):1604-11. | ||||||||||
| Title: | Genetic variation in a metabolic signaling pathway and colon and rectal cancer risk: mTOR, PTEN, STK11, RPKAA1, PRKAG2, TSC1, TSC2, PI3K and Akt1. | ||||||||||
| Author: | Slattery, Martha L|Herrick, Jennifer S|Lundgreen, Abbie|Fitzpatrick, Francis A|Curtin, Karen|Wolff, Roger K | ||||||||||
| PMID: | 20622004 | ||||||||||
| 7. | |||||||||||
| Journal: | J Biol Chem. 2011 Feb 25;286(8):6510-20. | ||||||||||
| Title: | mTOR-dependent regulation of PHLPP expression controls the rapamycin sensitivity in cancer cells. | ||||||||||
| Author: | Liu, Jianyu|Stevens, Payton D|Gao, Tianyan | ||||||||||
| PMID: | 21177869 | ||||||||||
| 8. | |||||||||||
| Journal: | Nutr Cancer. 2011 Nov;63(8):1226-34. | ||||||||||
| Title: | Diet and colorectal cancer: analysis of a candidate pathway using SNPS, haplotypes, and multi-gene assessment. | ||||||||||
| Author: | Slattery, Martha L|Lundgreen, Abbie|Herrick, Jennifer S|Caan, Bette J|Potter, John D|Wolff, Roger K | ||||||||||
| PMID: | 21999454 | ||||||||||
| 9. | |||||||||||
| Journal: | Bioorg Med Chem Lett. 2013 Mar 15;23(6):1600-3. | ||||||||||
| Title: | Fluorinated N,N'-diarylureas as AMPK activators. | ||||||||||
| Author: | Sviripa, Vitaliy|Zhang, Wen|Conroy, Michael D|Schmidt, Eric S|Liu, Alice X|Truong, Johnny|Liu, Chunming|Watt, David S | ||||||||||
| PMID: | 23414799 | ||||||||||
| 10. | |||||||||||
| Journal: | Mol Cell Biol. 2013 Nov;33(22):4594-605. | ||||||||||
| Title: | Downregulation of PHLPP expression contributes to hypoxia-induced resistance to chemotherapy in colon cancer cells. | ||||||||||
| Author: | Wen, Yang-An|Stevens, Payton D|Gasser, Michael L|Andrei, Romina|Gao, Tianyan | ||||||||||
| PMID: | 24061475 | ||||||||||
| 11. | |||||||||||
| Journal: | Biochem Pharmacol. 2014 Aug 1;90(3):265-75. | ||||||||||
| Title: | Autophagy inhibition switches low-dose camptothecin-induced premature senescence to apoptosis in human colorectal cancer cells. | ||||||||||
| Author: | Zhang, Jian-wei|Zhang, Shan-shan|Song, Jian-rui|Sun, Kai|Zong, Chen|Zhao, Qiu-dong|Liu, Wen-ting|Li, Rong|Wu, Meng-chao|Wei, Li-xin | ||||||||||
| PMID: | 24858802 | ||||||||||
| 12. | |||||||||||
| Journal: | Cell Signal. 2015 Aug;27(8):1557-68. | ||||||||||
| Title: | Growth-factor dependent expression of the translationally controlled tumour protein TCTP is regulated through the PI3-K/Akt/mTORC1 signalling pathway. | ||||||||||
| Author: | Bommer, Ulrich-Axel|Iadevaia, Valentina|Chen, Jiezhong|Knoch, Bianca|Engel, Martin|Proud, Christopher G | ||||||||||
| PMID: | 25936523 | ||||||||||
| 13. | |||||||||||
| Journal: | Autophagy. 2015;11(12):2309-22. | ||||||||||
| Title: | Epigenetic regulation of autophagy by the methyltransferase EZH2 through an MTOR-dependent pathway. | ||||||||||
| Author: | Wei, Fu-Zheng|Cao, Ziyang|Wang, Xi|Wang, Hui|Cai, Mu-Yan|Li, Tingting|Hattori, Naoko|Wang, Donglai|Du, Yipeng|Song, Boyan|Cao, Lin-Lin|Shen, Changchun|Wang, Lina|Wang, Haiying|Yang, Yang|Xie, Dan|Wang, Fan|Ushijima, Toshikazu|Zhao, Ying|Zhu, Wei-Guo | ||||||||||
| PMID: | 26735435 | ||||||||||
| 14. | |||||||||||
| Journal: | EBioMedicine. 2015 Nov 19;2(12):1944-56. | ||||||||||
| Title: | PP2AC Level Determines Differential Programming of p38-TSC-mTOR Signaling and Therapeutic Response to p38-Targeted Therapy in Colorectal Cancer. | ||||||||||
| Author: | Zhang, Yanjie|Wang, Xiaowen|Qin, Xiaoyu|Wang, Xinxin|Liu, Feng|White, Eileen|Zheng, X F Steven | ||||||||||
| PMID: | 26844273 | ||||||||||
| 15. | |||||||||||
| Journal: | EBioMedicine. 2015 Dec;2(12):1944-1956. | ||||||||||
| Title: | PP2AC Level Determines Differential Programming of p38-TSC-mTOR Signaling and Therapeutic Response to p38-Targeted Therapy in Colorectal Cancer. | ||||||||||
| Author: | Zhang, Yanjie|Wang, Xiaowen|Qin, Xiaoyu|Wang, Xinxin|Liu, Feng|White, Eileen|Zheng, X F Steven | ||||||||||
| PMID: | 28958491 | ||||||||||
| 16. | |||||||||||
| Journal: | Cancer Lett. 2016 Jun 28;376(1):83-94. | ||||||||||
| Title: | Gankyrin activates mTORC1 signaling by accelerating TSC2 degradation in colorectal cancer. | ||||||||||
| Author: | Qin, Xiaoyu|Wang, Xinxin|Liu, Feng|Morris, Laura E|Wang, Xiaowen|Jiang, Bin|Zhang, Yanjie | ||||||||||
| PMID: | 26975632 | ||||||||||
| 17. | |||||||||||
| Journal: | Oncotarget. 2016 Nov 15;7(46):75659-75671. | ||||||||||
| Title: | Curcumin targets the TFEB-lysosome pathway for induction of autophagy. | ||||||||||
| Author: | Zhang, Jianbin|Wang, Jigang|Xu, Jian|Lu, Yuanqiang|Jiang, Jiukun|Wang, Liming|Shen, Han-Ming|Xia, Dajing | ||||||||||
| PMID: | 27689333 | ||||||||||
| 18. | |||||||||||
| Journal: | Endocr Pathol. 2018 Mar;29(1):21-26. | ||||||||||
| Title: | Expanding the Spectrum of Colonic Manifestations in Tuberous Sclerosis: L-Cell Neuroendocrine Tumor Arising in the Background of Rectal PEComa. | ||||||||||
| Author: | Kolin, David L|Duan, Kai|Ngan, Bo|Gerstle, J Ted|Krzyzanowska, Monika K|Somers, Gino R|Mete, Ozgur | ||||||||||
| PMID: | 28733877 | ||||||||||
| 19. | |||||||||||
| Journal: | Oncotarget. 2017 Dec 22;9(4):4998-5015. | ||||||||||
| Title: | Osteopontin-integrin engagement induces HIF-1alpha-TCF12-mediated endothelial-mesenchymal transition to exacerbate colorectal cancer. | ||||||||||
| Author: | Fan, Chi-Shuan|Chen, Wei-Shone|Chen, Li-Li|Chen, Chia-Chi|Hsu, Yu-Ting|Chua, Kee Voon|Wang, Horng-Dar|Huang, Tze-Sing | ||||||||||
| PMID: | 29435158 | ||||||||||
| 20. | |||||||||||
| Journal: | J Nutr Biochem. 2018 Jul;57:276-286. | ||||||||||
| Title: | Piperine potentiates curcumin-mediated repression of mTORC1 signaling in human intestinal epithelial cells: implications for the inhibition of protein synthesis and TNFalpha signaling. | ||||||||||
| Author: | Kaur, Harleen|He, Bo|Zhang, Chenhua|Rodriguez, Elliott|Hage, David S|Moreau, Regis | ||||||||||
| PMID: | 29800814 | ||||||||||