Primary Site >> Colorectal Cancer

Gene >> TRAF2

Journal: J Biol Chem. 1999 Jan 29;274(5):2988-3000.
Title: Pyropheophorbide-a methyl ester-mediated photosensitization activates transcription factor NF-kappaB through the interleukin-1 receptor-dependent signaling pathway.
Author: Matroule, J Y|Bonizzi, G|Morliere, P|Paillous, N|Santus, R|Bours, V|Piette, J
PMID: 9915837
Journal: Carcinogenesis. 2002 Dec;23(12):2063-80.
Title: Development and molecular characterization of HCT-116 cell lines resistant to the tumor promoter and multiple stress-inducer, deoxycholate.
Author: Crowley-Weber, Cara L|Payne, Claire M|Gleason-Guzman, Mary|Watts, George S|Futscher, Bernard|Waltmire, Caroline N|Crowley, Cheray|Dvorakova, Katerina|Bernstein, Carol|Craven, Mary|Garewal, Harinder|Bernstein, Harris
PMID: 12507930
Journal: Oncogene. 2004 Mar 11;23(10):1885-95.
Title: Regulation of phorbol ester-mediated TRAF1 induction in human colon cancer cells through a PKC/RAF/ERK/NF-kappaB-dependent pathway.
Author: Wang, Xiaofu|Wang, Qingding|Hu, Wanqin|Evers, B Mark
PMID: 14981539
Journal: Br J Cancer. 2009 May 5;100(9):1415-24.
Title: Differential activation of JNK1 isoforms by TRAIL receptors modulate apoptosis of colon cancer cell lines.
Author: Mahalingam, D|Keane, M|Pirianov, G|Mehmet, H|Samali, A|Szegezdi, E
PMID: 19352384
Journal: J Cell Mol Med. 2010 Mar;14(3):710-25.
Title: HSP70 interacts with TRAF2 and differentially regulates TNFalpha signalling in human colon cancer cells.
Author: Dai, Shengming|Jiang, Lijun|Wang, Guisheng|Zhou, Xiangyang|Wei, Xiaomou|Cheng, Hongge|Wu, Zhen|Wei, Dong
PMID: 19243468
Journal: Cancer Res. 2010 Jun 15;70(12):5024-33.
Title: Traf2- and Nck-interacting kinase is essential for Wnt signaling and colorectal cancer growth.
Author: Shitashige, Miki|Satow, Reiko|Jigami, Takafumi|Aoki, Kazunori|Honda, Kazufumi|Shibata, Tatsuhiro|Ono, Masaya|Hirohashi, Setsuo|Yamada, Tesshi
PMID: 20530691
Journal: J Biol Chem. 2010 Aug 20;285(34):26289-94.
Title: Traf2- and Nck-interacting kinase is essential for canonical Wnt signaling in Xenopus axis formation.
Author: Satow, Reiko|Shitashige, Miki|Jigami, Takafumi|Honda, Kazufumi|Ono, Masaya|Hirohashi, Setsuo|Yamada, Tesshi
PMID: 20566648
Journal: Hum Cell. 2011 Sep;24(3):121-6.
Title: Enormous influence of TNIK knockdown on intracellular signals and cell survival.
Author: Gui, Jinghua|Yang, Baotian|Wu, Jinyun|Zhou, Xiumei
PMID: 21710359
Journal: Proteomics. 2011 Aug;11(16):3390-401.
Title: Quantitative phosphoproteomics of transforming growth factor-beta signaling in colon cancer cells.
Author: Ali, Naveid A|Molloy, Mark P
PMID: 21751366
Journal: Int J Mol Epidemiol Genet. 2011;2(4):328-38. Epub 2011 Oct 20.
Title: Tumor necrosis factor-related genes and colon and rectal cancer.
Author: Slattery, Martha L|Lundgreen, Abbie|Bondurant, Kristina L|Wolff, Roger K
PMID: 22199996
Journal: J Biol Chem. 2012 Jul 27;287(31):25881-92.
Title: Tumor necrosis factor receptor-associated factor family protein 2 is a key mediator of the epidermal growth factor-induced ribosomal S6 kinase 2/cAMP-responsive element-binding protein/Fos protein signaling pathway.
Author: Peng, Cong|Zhu, Feng|Wen, Weihong|Yao, Ke|Li, Shengqing|Zykova, Tatyana|Liu, Kangdong|Li, Xiang|Ma, Wei-Ya|Bode, Ann M|Dong, Zigang
PMID: 22685297
Journal: Bioorg Med Chem Lett. 2013 Jan 15;23(2):569-73.
Title: Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors.
Author: Ho, Koc-Kan|Parnell, K Mark|Yuan, Yi|Xu, Yong|Kultgen, Steven G|Hamblin, Steven|Hendrickson, Thomas F|Luo, Bai|Foulks, Jason M|McCullar, Michael V|Kanner, Steven B
PMID: 23232060
Journal: Cell Signal. 2013 Oct;25(10):1993-2002.
Title: Activation of AMP-activated protein kinase (AMPK) mediates plumbagin-induced apoptosis and growth inhibition in cultured human colon cancer cells.
Author: Chen, Min-Bin|Zhang, Yan|Wei, Mu-Xin|Shen, Wei|Wu, Xiao-Yang|Yao, Chen|Lu, Pei-Hua
PMID: 23712032
Journal: Oncogenesis. 2014 Feb 24;2:e89.
Title: The essential role of TNIK gene amplification in gastric cancer growth.
Author: Yu, D-H|Zhang, X|Wang, H|Zhang, L|Chen, H|Hu, M|Dong, Z|Zhu, G|Qian, Z|Fan, J|Su, X|Xu, Y|Zheng, L|Dong, H|Yin, X|Ji, Q|Ji, J
PMID: 24566388
Journal: BMC Cancer. 2015 Oct 24;15:794.
Title: Prognostic significance of Traf2- and Nck- interacting kinase (TNIK) in colorectal cancer.
Author: Takahashi, Hidenori|Ishikawa, Toshiaki|Ishiguro, Megumi|Okazaki, Satoshi|Mogushi, Kaoru|Kobayashi, Hirotoshi|Iida, Satoru|Mizushima, Hiroshi|Tanaka, Hiroshi|Uetake, Hiroyuki|Sugihara, Kenichi
PMID: 26499327
Journal: Pharmacol Ther. 2015 Dec;156:1-9.
Title: Therapeutic targets in the Wnt signaling pathway: Feasibility of targeting TNIK in colorectal cancer.
Author: Masuda, Mari|Sawa, Masaaki|Yamada, Tesshi
PMID: 26542362
Journal: Expert Opin Ther Targets. 2016;20(4):419-29.
Title: Targeting the Wnt signaling pathway in colorectal cancer.
Author: Sawa, Masaaki|Masuda, Mari|Yamada, Tesshi
PMID: 26439805
Journal: J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Mar 1;1014:17-23.
Title: Metabolomics study on the antitumor effect of marine natural compound flexibilide in HCT-116 colon cancer cell line.
Author: Gao, Dan|Wang, Yini|Xie, Weiyi|Yang, Ti|Jiang, Yuyang|Guo, Yuewei|Guan, Jin|Liu, Hongxia
PMID: 26859520
Journal: Nat Commun. 2016 Aug 26;7:12586.
Title: TNIK inhibition abrogates colorectal cancer stemness.
Author: Masuda, Mari|Uno, Yuko|Ohbayashi, Naomi|Ohata, Hirokazu|Mimata, Ayako|Kukimoto-Niino, Mutsuko|Moriyama, Hideki|Kashimoto, Shigeki|Inoue, Tomoko|Goto, Naoko|Okamoto, Koji|Shirouzu, Mikako|Sawa, Masaaki|Yamada, Tesshi
PMID: 27562646
Journal: Sci Rep. 2016 Sep 21;6:33534.
Title: Comprehensive Modeling and Discovery of Mebendazole as a Novel TRAF2- and NCK-interacting Kinase Inhibitor.
Author: Tan, Zhi|Chen, Lu|Zhang, Shuxing
PMID: 27650168
Journal: Cancer Sci. 2017 May;108(5):818-823.
Title: Emergence of TNIK inhibitors in cancer therapeutics.
Author: Yamada, Tesshi|Masuda, Mari
PMID: 28208209
Journal: Biochem Biophys Res Commun. 2018 Jun 2;500(2):196-203.
Title: CDCA3 promotes cell proliferation by activating the NF-kappaB/cyclin D1 signaling pathway in colorectal cancer.
Author: Zhang, Wei|Lu, Yanxia|Li, Xiaomin|Zhang, Jianming|Zheng, Lin|Zhang, Wenjuan|Lin, Chun|Lin, Weihao|Li, Xuenong
PMID: 29627567