Primary Site >> Colorectal Cancer
Gene >> TRAF2
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Ref: Pyropheophorbide-a methyl ester-mediated photosensitization activates transcription factor NF-kappaB through the interleukin-1 receptor-dependent signaling pathway. PMID: 9915837 |
Ref: Development and molecular characterization of HCT-116 cell lines resistant to the tumor promoter and multiple stress-inducer, deoxycholate. PMID: 12507930 |
Ref: Regulation of phorbol ester-mediated TRAF1 induction in human colon cancer cells through a PKC/RAF/ERK/NF-kappaB-dependent pathway. PMID: 14981539 |
Ref: Differential activation of JNK1 isoforms by TRAIL receptors modulate apoptosis of colon cancer cell lines. PMID: 19352384 |
Ref: HSP70 interacts with TRAF2 and differentially regulates TNFalpha signalling in human colon cancer cells. PMID: 19243468 Ref: Traf2- and Nck-interacting kinase is essential for Wnt signaling and colorectal cancer growth. PMID: 20530691 Ref: Traf2- and Nck-interacting kinase is essential for canonical Wnt signaling in Xenopus axis formation. PMID: 20566648 |
Ref: Enormous influence of TNIK knockdown on intracellular signals and cell survival. PMID: 21710359 Ref: Quantitative phosphoproteomics of transforming growth factor-beta signaling in colon cancer cells. PMID: 21751366 Ref: Tumor necrosis factor-related genes and colon and rectal cancer. PMID: 22199996 |
Ref: Tumor necrosis factor receptor-associated factor family protein 2 is a key mediator of the epidermal growth factor-induced ribosomal S6 kinase 2/cAMP-responsive element-binding protein/Fos protein signaling pathway. PMID: 22685297 |
Ref: Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors. PMID: 23232060 Ref: Activation of AMP-activated protein kinase (AMPK) mediates plumbagin-induced apoptosis and growth inhibition in cultured human colon cancer cells. PMID: 23712032 |
Ref: The essential role of TNIK gene amplification in gastric cancer growth. PMID: 24566388 |
Ref: Prognostic significance of Traf2- and Nck- interacting kinase (TNIK) in colorectal cancer. PMID: 26499327 Ref: Therapeutic targets in the Wnt signaling pathway: Feasibility of targeting TNIK in colorectal cancer. PMID: 26542362 |
Ref: Targeting the Wnt signaling pathway in colorectal cancer. PMID: 26439805 Ref: Metabolomics study on the antitumor effect of marine natural compound flexibilide in HCT-116 colon cancer cell line. PMID: 26859520 Ref: TNIK inhibition abrogates colorectal cancer stemness. PMID: 27562646 Ref: Comprehensive Modeling and Discovery of Mebendazole as a Novel TRAF2- and NCK-interacting Kinase Inhibitor. PMID: 27650168 |
Ref: Emergence of TNIK inhibitors in cancer therapeutics. PMID: 28208209 |
Ref: CDCA3 promotes cell proliferation by activating the NF-kappaB/cyclin D1 signaling pathway in colorectal cancer. PMID: 29627567 |