Primary Site >> Colorectal Cancer

Gene >> TPM3

Journal: Princess Takamatsu Symp. 1991;22:153-70.
Title: The trk family of oncogenes and neurotrophin receptors.
Author: Lamballe, F|Klein, R|Barbacid, M
PMID: 1844238
Journal: Clin Exp Immunol. 1999 Nov;118(2):219-27.
Title: Externalization of tropomyosin isoform 5 in colon epithelial cells.
Author: Kesari, K V|Yoshizaki, N|Geng, X|Lin, J J|Das, K M
PMID: 10540182
Journal: Gastroenterology. 2002 Jul;123(1):152-62.
Title: Isolation and sequencing of a novel tropomyosin isoform preferentially associated with colon cancer.
Author: Lin, Jenny L-C|Geng, Xin|Bhattacharya, Sangeeta Das|Yu, Jae-Ran|Reiter, Rebecca S|Sastri, Bhagyalakshmi|Glazier, Kenneth D|Mirza, Zafar K|Wang, Kenneth K|Amenta, Peter S|Das, Kiron M|Lin, Jim J-C
PMID: 12105844
Journal: Clin Biochem. 2008 Oct;41(14-15):1224-36.
Title: Expression of chloride intracellular channel protein 1 (CLIC1) and tumor protein D52 (TPD52) as potential biomarkers for colorectal cancer.
Author: Petrova, Darinka Todorova|Asif, Abdul R|Armstrong, Victor W|Dimova, Ivanka|Toshev, Svetoslav|Yaramov, Nikolay|Oellerich, Michael|Toncheva, Draga
PMID: 18710659
Journal: World J Gastroenterol. 2008 Sep 14;14(34):5290-300.
Title: Ileal lesions in patients with ulcerative colitis after ileo-rectal anastomosis: relationship with colonic metaplasia.
Author: Biancone, Livia|Calabrese, Emma|Palmieri, Giampiero|Petruzziello, Carmelina|Onali, Sara|Sica, Giuseppe-Sigismondo|Cossignani, Marta|Condino, Giovanna|Das, Kiron-Moy|Pallone, Francesco
PMID: 18785281
Journal: Mol Pharmacol. 2009 Jul;76(1):183-91.
Title: Mesalamine suppresses the expression of TC22, a novel tropomyosin isoform associated with colonic neoplasia.
Author: Das, Koushik K|Bajpai, Manisha|Kong, Yingxin|Liu, Jianying|Geng, Xin|Das, Kiron M
PMID: 19369484
Journal: Mol Oncol. 2014 Dec;8(8):1495-507.
Title: The TPM3-NTRK1 rearrangement is a recurring event in colorectal carcinoma and is associated with tumor sensitivity to TRKA kinase inhibition.
Author: Ardini, Elena|Bosotti, Roberta|Borgia, Andrea Lombardi|De Ponti, Cristina|Somaschini, Alessio|Cammarota, Rosaria|Amboldi, Nadia|Raddrizzani, Laura|Milani, Andrea|Magnaghi, Paola|Ballinari, Dario|Casero, Daniele|Gasparri, Fabio|Banfi, Patrizia|Avanzi, Nill
PMID: 24962792
Journal: Br J Pharmacol. 2015 Nov;172(21):5211-23.
Title: Crucial role of the orexin-B C-terminus in the induction of OX1 receptor-mediated apoptosis: analysis by alanine scanning, molecular modelling and site-directed mutagenesis.
Author: Nicole, Pascal|Couvineau, Pierre|Jamin, Nadege|Voisin, Thierry|Couvineau, Alain
PMID: 26282891
Journal: Oncotarget. 2015 Nov 17;6(36):39028-35.
Title: NTRK1 rearrangement in colorectal cancer patients: evidence for actionable target using patient-derived tumor cell line.
Author: Lee, Su Jin|Li, Gang Gary|Kim, Seung Tae|Hong, Min Eui|Jang, Jiryeon|Yoon, Nara|Ahn, Soo Min|Murphy, Danielle|Christiansen, Jason|Wei, Ge|Hornby, Zachary|Lee, Dong Woo|Park, Joon Oh|Park, Young Suk|Lim, Ho Yeong|Hong, Sung No|Kim, Seok-Hyeong|Kang, Won Ki
PMID: 26472021
Journal: Cancer Lett. 2015 Aug 28;365(1):107-11.
Title: Chromosomal rearrangements involving the NTRK1 gene in colorectal carcinoma.
Author: Creancier, Laurent|Vandenberghe, Isabelle|Gomes, Bruno|Dejean, Caroline|Blanchet, Jean-Christophe|Meilleroux, Julie|Guimbaud, Rosine|Selves, Janick|Kruczynski, Anna
PMID: 26001971
Journal: Biomed Res Int. 2015;2015:365068.
Title: Label-free quantitative mass spectrometry reveals a panel of differentially expressed proteins in colorectal cancer.
Author: Fan, Nai-Jun|Gao, Jiang-Ling|Liu, Yan|Song, Wei|Zhang, Zhan-Yang|Gao, Chun-Fang
PMID: 25699276
Journal: J Natl Cancer Inst. 2015 Nov 12;108(1). pii: djv306.
Title: Sensitivity to Entrectinib Associated With a Novel LMNA-NTRK1 Gene Fusion in Metastatic Colorectal Cancer.
Author: Sartore-Bianchi, Andrea|Ardini, Elena|Bosotti, Roberta|Amatu, Alessio|Valtorta, Emanuele|Somaschini, Alessio|Raddrizzani, Laura|Palmeri, Laura|Banfi, Patrizia|Bonazzina, Erica|Misale, Sandra|Marrapese, Giovanna|Leone, Antonella|Alzani, Rachele|Luo, David|
PMID: 26563355
Journal: Oncotarget. 2016 Feb 16;7(7):8399-412.
Title: NTRK1 fusions for the therapeutic intervention of Korean patients with colon cancer.
Author: Park, Do Youn|Choi, Chan|Shin, Eunji|Lee, Jae Hyuk|Kwon, Chae Hwa|Jo, Hong-Jae|Kim, Hyeong-Rok|Kim, Hyun Sung|Oh, Nahmgun|Lee, Ji Shin|Park, Ok Ku|Park, Eok|Park, Jonghoon|Shin, Jong-Yeon|Kim, Jong-Il|Seo, Jeong-Sun|Park, Hee Dong|Park, Joonghoon
PMID: 26716414
Journal: Am J Surg Pathol. 2017 Nov;41(11):1547-1551.
Title: Pan-Trk Immunohistochemistry Is an Efficient and Reliable Screen for the Detection of NTRK Fusions.
Author: Hechtman, Jaclyn F|Benayed, Ryma|Hyman, David M|Drilon, Alexander|Zehir, Ahmet|Frosina, Denise|Arcila, Maria E|Dogan, Snjezana|Klimstra, David S|Ladanyi, Marc|Jungbluth, Achim A
PMID: 28719467
Journal: Mol Cancer Ther. 2017 Oct;16(10):2130-2143.
Title: Mechanisms of Resistance to NTRK Inhibitors and Therapeutic Strategies in NTRK1-Rearranged Cancers.
Author: Fuse, Miho J|Okada, Koutaroh|Oh-Hara, Tomoko|Ogura, Hayato|Fujita, Naoya|Katayama, Ryohei
PMID: 28751539
Journal: Cancer Med. 2017 Dec;6(12):2972-2983.
Title: In vivo imaging xenograft models for the evaluation of anti-brain tumor efficacy of targeted drugs.
Author: Kita, Kenji|Arai, Sachiko|Nishiyama, Akihiro|Taniguchi, Hirokazu|Fukuda, Koji|Wang, Rong|Yamada, Tadaaki|Takeuchi, Shinji|Tange, Shoichiro|Tajima, Atsushi|Nakada, Mitsutoshi|Yasumoto, Kazuo|Motoo, Yoshiharu|Murakami, Takashi|Yano, Seiji
PMID: 29125233
Journal: Anal Biochem. 2018 Mar 15;545:78-83.
Title: A novel in-cell ELISA method for screening of compounds inhibiting TRKA phosphorylation, using KM12cell line harboring TRKA rearrangement.
Author: Pandre, Manoj Kumar|Shaik, Shama|Satya Pratap, Veera Venkata Valluri|Yadlapalli, Prasad|Yanamandra, Mahesh|Mitra, Sayan
PMID: 29360440
Journal: Clin Cancer Res. 2018 May 15;24(10):2357-2369.
Title: Foretinib Overcomes Entrectinib Resistance Associated with the NTRK1 G667C Mutation in NTRK1 Fusion-Positive Tumor Cells in a Brain Metastasis Model.
Author: Nishiyama, Akihiro|Yamada, Tadaaki|Kita, Kenji|Wang, Rong|Arai, Sachiko|Fukuda, Koji|Tanimoto, Azusa|Takeuchi, Shinji|Tange, Shoichiro|Tajima, Atsushi|Furuya, Noritaka|Kinoshita, Takayoshi|Yano, Seiji
PMID: 29463555