Primary Site >> Colorectal Cancer

Gene >> TPM3

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Ref: The trk family of oncogenes and neurotrophin receptors.
PMID: 1844238
Ref: Externalization of tropomyosin isoform 5 in colon epithelial cells.
PMID: 10540182
Ref: Isolation and sequencing of a novel tropomyosin isoform preferentially associated with colon cancer.
PMID: 12105844
Ref: Expression of chloride intracellular channel protein 1 (CLIC1) and tumor protein D52 (TPD52) as potential biomarkers for colorectal cancer.
PMID: 18710659
Ref: Ileal lesions in patients with ulcerative colitis after ileo-rectal anastomosis: relationship with colonic metaplasia.
PMID: 18785281
Ref: Mesalamine suppresses the expression of TC22, a novel tropomyosin isoform associated with colonic neoplasia.
PMID: 19369484
Ref: The TPM3-NTRK1 rearrangement is a recurring event in colorectal carcinoma and is associated with tumor sensitivity to TRKA kinase inhibition.
PMID: 24962792
Ref: Label-free quantitative mass spectrometry reveals a panel of differentially expressed proteins in colorectal cancer.
PMID: 25699276
Ref: Chromosomal rearrangements involving the NTRK1 gene in colorectal carcinoma.
PMID: 26001971
Ref: Crucial role of the orexin-B C-terminus in the induction of OX1 receptor-mediated apoptosis: analysis by alanine scanning, molecular modelling and site-directed mutagenesis.
PMID: 26282891
Ref: NTRK1 rearrangement in colorectal cancer patients: evidence for actionable target using patient-derived tumor cell line.
PMID: 26472021
Ref: Sensitivity to Entrectinib Associated With a Novel LMNA-NTRK1 Gene Fusion in Metastatic Colorectal Cancer.
PMID: 26563355
Ref: NTRK1 fusions for the therapeutic intervention of Korean patients with colon cancer.
PMID: 26716414
Ref: Pan-Trk Immunohistochemistry Is an Efficient and Reliable Screen for the Detection of NTRK Fusions.
PMID: 28719467
Ref: Mechanisms of Resistance to NTRK Inhibitors and Therapeutic Strategies in NTRK1-Rearranged Cancers.
PMID: 28751539
Ref: In vivo imaging xenograft models for the evaluation of anti-brain tumor efficacy of targeted drugs.
PMID: 29125233
Ref: A novel in-cell ELISA method for screening of compounds inhibiting TRKA phosphorylation, using KM12cell line harboring TRKA rearrangement.
PMID: 29360440
Ref: Foretinib Overcomes Entrectinib Resistance Associated with the NTRK1 G667C Mutation in NTRK1 Fusion-Positive Tumor Cells in a Brain Metastasis Model.
PMID: 29463555