Primary Site >> Colorectal Cancer

Gene >> TP73

Journal: Int J Oncol. 1998 Aug;13(2):319-23.
Title: Mutational analysis of the p73 gene localized at chromosome 1p36.3 in colorectal carcinomas.
Author: Sunahara, M|Ichimiya, S|Nimura, Y|Takada, N|Sakiyama, S|Sato, Y|Todo, S|Adachi, W|Amano, J|Nakagawara, A
PMID: 9664127
Journal: Oncogene. 1999 Jan 28;18(4):1061-6.
Title: p73 at chromosome 1p36.3 is lost in advanced stage neuroblastoma but its mutation is infrequent.
Author: Ichimiya, S|Nimura, Y|Kageyama, H|Takada, N|Sunahara, M|Shishikura, T|Nakamura, Y|Sakiyama, S|Seki, N|Ohira, M|Kaneko, Y|McKeon, F|Caput, D|Nakagawara, A
PMID: 10023682
Journal: Eur J Surg Oncol. 1999 Apr;25(2):194-8.
Title: Infrequent somatic mutations of the p73 gene in various human cancers.
Author: Han, S|Semba, S|Abe, T|Makino, N|Furukawa, T|Fukushige, S|Takahashi, H|Sakurada, A|Sato, M|Shiiba, K|Matsuno, S|Nimura, Y|Nakagawara, A|Horii, A
PMID: 10218465
Journal: Proc Natl Acad Sci U S A. 1999 Dec 7;96(25):14517-22.
Title: Identification and classification of p53-regulated genes.
Author: Yu, J|Zhang, L|Hwang, P M|Rago, C|Kinzler, K W|Vogelstein, B
PMID: 10588737
Journal: Neoplasia. 2000 Nov-Dec;2(6):514-22.
Title: Evaluation of 1p losses in primary carcinomas, local recurrences and peripheral metastases from colorectal cancer patients.
Author: Thorstensen, L|Qvist, H|Heim, S|Liefers, G J|Nesland, J M|Giercksky, K E|Lothe, R A
PMID: 11228544
Journal: Biochem Biophys Res Commun. 2001 May 4;283(2):327-33.
Title: p73beta, a variant of p73, enhances Wnt/beta-catenin signaling in Saos-2 cells.
Author: Ueda, Y|Hijikata, M|Takagi, S|Takada, R|Takada, S|Chiba, T|Shimotohno, K
PMID: 11327702
Journal: Int J Oncol. 2001 Jul;19(1):49-52.
Title: Loss of p27 expression predicts poor prognosis in patients with Dukes' B stage or proximal colorectal cancer.
Author: Zhang, H|Sun, X F
PMID: 11408921
Journal: Gene Ther. 2001 Sep;8(18):1401-8.
Title: Adenovirus-mediated transfer of the p53 family genes, p73 and p51/p63 induces cell cycle arrest and apoptosis in colorectal cancer cell lines: potential application to gene therapy of colorectal cancer.
Author: Sasaki, Y|Morimoto, I|Ishida, S|Yamashita, T|Imai, K|Tokino, T
PMID: 11571580
Journal: J Int Med Res. 2001 Jul-Aug;29(4):297-303.
Title: Expression of p73 in colorectal carcinoma: clinicopathological relevance.
Author: Liu, L|Cui, X|Sakaguchi, T|Sasaki, M|Suda, T|Hatakeyama, K
PMID: 11675903
Journal: Biochem J. 2002 Jun 1;364(Pt 2):441-7.
Title: Ascorbate up-regulates MLH1 (Mut L homologue-1) and p73: implications for the cellular response to DNA damage.
Author: Catani, M Valeria|Costanzo, Antonio|Savini, Isabella|Levrero, Massimo|de Laurenzi, Vincenzo|Wang, Jean Y J|Melino, Gerry|Avigliano, Luciana
PMID: 12023887
Journal: J Pathol. 2002 Dec;198(4):417-27.
Title: Differential expression of p63 isoforms in normal tissues and neoplastic cells.
Author: Nylander, Karin|Vojtesek, Borek|Nenutil, Rudolf|Lindgren, Britta|Roos, Goran|Zhanxiang, Wang|Sjostrom, Bjorn|Dahlqvist, Ake|Coates, Philip J
PMID: 12434410
Journal: Cancer Lett. 2002 Jul 8;181(1):81-5.
Title: No associations of p73 G4C14-to-A4T14 at exon 2 and p53 Arg72Pro polymorphisms with the risk of digestive tract cancers in Japanese.
Author: Hamajima, Nobuyuki|Matsuo, Keitaro|Suzuki, Takashi|Nakamura, Tsuneya|Matsuura, Akira|Hatooka, Shunzo|Shinoda, Masayuki|Kodera, Yasuhiro|Yamamura, Yoshitaka|Hirai, Takashi|Kato, Tomoyuki|Tajima, Kazuo
PMID: 12430182
Journal: Clin Cancer Res. 2002 Jan;8(1):165-70.
Title: p73 overexpression is a prognostic factor in patients with colorectal adenocarcinoma.
Author: Sun, Xiao-Feng
PMID: 11801554
Journal: Jpn J Clin Oncol. 2003 May;33(5):215-20.
Title: p73 Overexpression and angiogenesis in human colorectal carcinoma.
Author: Guan, Ming|Peng, Hai-Xia|Yu, Bo|Lu, Yuan
PMID: 12865464
Journal: Genes Chromosomes Cancer. 2004 Mar;39(3):257-62.
Title: Intronic deletion affecting a negative regulatory region of TP73 is related to breast and colorectal carcinomas.
Author: Pena, Cristina|Garcia, Jose M|Dominguez, Gemma|Silva, Javier|Garcia, Vanesa|Carcereny, Enric|Vargas, Javier|Provencio, Mariano|Espana, Pilar|Bonilla, Felix
PMID: 14732927
Journal: World J Gastroenterol. 2004 Dec 1;10(23):3441-54.
Title: Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis.
Author: Xu, Xiao-Li|Yu, Jian|Zhang, Hong-Yu|Sun, Meng-Hong|Gu, Jun|Du, Xiang|Shi, Da-Ren|Wang, Peng|Yang, Zhen-Hua|Zhu, Jing-De
PMID: 15526363
Journal: Carcinogenesis. 2005 Jan;26(1):103-7.
Title: Polymorphism of the p73 gene in relation to colorectal cancer risk and survival.
Author: Pfeifer, Daniella|Arbman, Gunnar|Sun, Xiao-Feng
PMID: 15485994
Journal: Growth Horm IGF Res. 2005 Dec;15(6):388-96.
Title: The p53-family members p63 and p73 inhibit insulin-like growth factor-I receptor gene expression in colon cancer cells.
Author: Nahor, Irit|Abramovitch, Shirley|Engeland, Kurt|Werner, Haim
PMID: 16181796
Journal: Int J Radiat Oncol Biol Phys. 2006 Jul 15;65(4):1143-8.
Title: Expression of the p73 protein in rectal cancers with or without preoperative radiotherapy.
Author: Pfeifer, Daniella|Gao, Jingfang|Adell, Gunnar|Sun, Xiao-Feng
PMID: 16750334
Journal: J Pathol. 2006 Dec;210(4):385-9.
Title: Regulating p73 isoforms in human tumours.
Author: Coates, P J
PMID: 17044134
Journal: J Pathol. 2006 Dec;210(4):390-7.
Title: The presence of an intronic deletion in p73 and high levels of ZEB1 alter the TAp73/DeltaTAp73 ratio in colorectal carcinomas.
Author: Dominguez, G|Pena, C|Silva, J|Garcia, J M|Garcia, V|Rodriguez, R|Cantos, B|Citores, M J|Espana, P|Bonilla, F
PMID: 17029218
Journal: Proc Natl Acad Sci U S A. 2006 Jul 18;103(29):11003-8.
Title: Small-molecule modulators of p53 family signaling and antitumor effects in p53-deficient human colon tumor xenografts.
Author: Wang, Wenge|Kim, Seok-Hyun|El-Deiry, Wafik S
PMID: 16835297
Journal: Mol Cancer Ther. 2006 Feb;5(2):400-10.
Title: c-Abl-independent p73 stabilization during gemcitabine- or 4'-thio-beta-D-arabinofuranosylcytosine-induced apoptosis in wild-type and p53-null colorectal cancer cells.
Author: Thottassery, Jaideep V|Westbrook, Louise|Someya, Hitoshi|Parker, William B
PMID: 16505115
Journal: Cancer Biol Ther. 2006 Jul;5(7):794-803. Epub 2006 Jul 28.
Title: Questioning the oncogenic role of DeltaNp73alpha in different cell lines expressing p53 or not.
Author: Marrazzo, Eleonora|Marchini, Sergio|Previdi, Sara|Broggini, Massimo
PMID: 16721041
Journal: Int J Cancer. 2007 Feb 1;120(3):506-13.
Title: In vivo evaluation of the role of DNp73alpha protein in regulating the p53-dependent apoptotic pathway after treatment with cytotoxic drugs.
Author: Sabatino, Maria Antonietta|Previdi, Sara|Broggini, Massimo
PMID: 17096333
Journal: Oncogene. 2008 Apr 17;27(18):2583-93. Epub 2007 Nov 5.
Title: Wild-type p53 and p73 negatively regulate expression of proliferation related genes.
Author: Scian, M J|Carchman, E H|Mohanraj, L|Stagliano, K E R|Anderson, M A E|Deb, D|Crane, B M|Kiyono, T|Windle, B|Deb, S P|Deb, S
PMID: 17982488
Journal: Cancer Sci. 2008 Feb;99(2):253-9.
Title: Aberrant methylation status of known methylation-sensitive CpG islands in gastrointestinal stromal tumors without any correlation to the state of c-kit and PDGFRA gene mutations and their malignancy.
Author: Saito, Kana|Sakurai, Shinji|Sano, Takaaki|Sakamoto, Kazuha|Asao, Takayuki|Hosoya, Yoshinori|Nakajima, Takashi|Kuwano, Hiroyuki
PMID: 18271923
Journal: Oncogene. 2008 Sep 11;27(40):5303-14.
Title: E2F-1 transcriptional activity is a critical determinant of Mdm2 antagonist-induced apoptosis in human tumor cell lines.
Author: Kitagawa, M|Aonuma, M|Lee, S H|Fukutake, S|McCormick, F
PMID: 18521084
Journal: Int J Cancer. 2008 Sep 1;123(5):1060-7.
Title: p73 Isoforms affect VEGF, VEGF165b and PEDF expression in human colorectal tumors: VEGF165b downregulation as a marker of poor prognosis.
Author: Diaz, Raquel|Pena, Cristina|Silva, Javier|Lorenzo, Yolanda|Garcia, Vanesa|Garcia, Jose M|Sanchez, Antonio|Espinosa, Pablo|Yuste, Rosario|Bonilla, Felix|Dominguez, Gemma
PMID: 18546269
Journal: Cancer Res. 2008 Oct 15;68(20):8231-9.
Title: Netrin-1 induces apoptosis in human cervical tumor cells via the TAp73alpha tumor suppressor.
Author: Roperch, Jean-Pierre|El Ouadrani, Karima|Hendrix, Ann|Emami, Shahin|De Wever, Olivier|Melino, Gerry|Gespach, Christian
PMID: 18922894
Journal: Cancer Biol Ther. 2008 Dec;7(12):2039-46.
Title: Non-genotoxic anti-neoplastic effects of ellipticine derivative NSC176327 in p53-deficient human colon carcinoma cells involve stimulation of p73.
Author: Lu, Chao|Wang, Wenge|El-Deiry, Wafik S
PMID: 19106635
Journal: Colorectal Dis. 2009 Nov;11(9):960-3.
Title: p73 expression and its clinical significance in colorectal cancer.
Author: Su, X-L|Ouyang, X-H|Yan, M-R|Liu, G-R
PMID: 19016816
Journal: BMC Biol. 2009 Jun 26;7:35.
Title: Effect of hydroxyurea on the promoter occupancy profiles of tumor suppressor p53 and p73.
Author: Huang, Vera|Lu, Xin|Jiang, Yong|Wang, Jean Y J
PMID: 19558638
Journal: Radiother Oncol. 2009 Aug;92(2):215-20.
Title: Significance of an exon 2 G4C14-to-A4T14 polymorphism in the p73 gene on survival in rectal cancer patients with or without preoperative radiotherapy.
Author: Loof, Jasmine|Pfeifer, Daniella|Adell, Gunnar|Sun, Xiao-Feng
PMID: 19581013
Journal: Proteomics. 2009 Jul;9(13):3535-48.
Title: Novel functional profiling approach combining reverse phase protein microarrays and human 3-D ex vivo tissue cultures: expression of apoptosis-related proteins in human colon cancer.
Author: Pirnia, Farzaneh|Pawlak, Michael|Thallinger, Gerhard G|Gierke, Berthold|Templin, Markus F|Kappeler, Andi|Betticher, Daniel C|Gloor, Beat|Borner, Markus M
PMID: 19609961
Journal: Cancer Causes Control. 2009 Nov;20(9):1769-77.
Title: Genetic variants in the cell cycle control pathways contribute to early onset colorectal cancer in Lynch syndrome.
Author: Chen, Jinyun|Etzel, Carol J|Amos, Christopher I|Zhang, Qing|Viscofsky, Nancy|Lindor, Noralane M|Lynch, Patrick M|Frazier, Marsha L
PMID: 19690970
Journal: Tunis Med. 2009 Apr;87(4):267-72.
Title: [P73 gene expression in colorectal adenocarcinoma: a prognostic or etiopathogenetic factor?].
Author: Ben Mahmoud, Lilia Kria|Toumi, Amira Arfaoui|Chaar, Ines|Lahmer, Ahlem|Khalfallah, Tahar|Mzabi, Sabeh Regaya|Bouraoui, Saadia
PMID: 19835284
Journal: Cancer Biol Ther. 2009 Nov;8(22):2186-93. Epub 2009 Nov 27.
Title: The combination of 5-fluorouracil plus p53 pathway restoration is associated with depletion of p53-deficient or mutant p53-expressing putative colon cancer stem cells.
Author: Huang, Catherine|Zhang, Xiang M|Tavaluc, Raluca T|Hart, Lori S|Dicker, David T|Wang, Wenge|El-Deiry, Wafik S
PMID: 19923910
Journal: Virchows Arch. 2010 Sep;457(3):359-68.
Title: Association of a p73 exon 2 GC/AT polymorphism with colorectal cancer risk and survival in Tunisian patients.
Author: Arfaoui, Amira Toumi|Kriaa, Lilia Ben Mahmoud|El Hadj, Olfa El Amine|Ben Hmida, Majid A|Khiari, Myriam|Khalfallah, T|Gharbi, Lasaad|Mzabi, Sabeh|Bouraoui, Sadaa
PMID: 20644956
Journal: Appl Immunohistochem Mol Morphol. 2010 Dec;18(6):546-54.
Title: Relationship between p73 polymorphism and the immunohistochemical profile of the full-length (TAp73) and NH2-truncated (DeltaNp73) isoforms in Tunisian patients.
Author: Arfaoui, Amira Toumi|Ben Mahmoud, Lilia Kriaa|Ben Hmida, Abdelmajid|Khiari, Mariem|Mohamed, Amine Lounis|Chaar, Ines|Khalfallah, Taher|Regaya, Sabeh Mzabi|Bouraoui, Saadia
PMID: 20733477
Journal: World J Gastroenterol. 2010 Sep 21;16(35):4448-54.
Title: p73 G4C14 to A4T14 polymorphism is associated with colorectal cancer risk and survival.
Author: Lee, Kyung-Eun|Hong, Young-Seoub|Kim, Byoung-Gwon|Kim, Na-Young|Lee, Kyoung-Mu|Kwak, Jong-Young|Roh, Mee-Sook
PMID: 20845513
Journal: J Transl Med. 2010 Feb 10;8:15.
Title: TAp73 is one of the genes responsible for the lack of response to chemotherapy depending on B-Raf mutational status.
Author: Herreros-Villanueva, Marta|Muniz, Pilar|Garcia-Giron, Carlos|Cavia-Saiz, Monica|del Corral, Maria J Coma
PMID: 20146801
Journal: FASEB J. 2010 Jun;24(6):2126-34.
Title: Securinine induces p73-dependent apoptosis preferentially in p53-deficient colon cancer cells.
Author: Rana, Sonia|Gupta, Kalpana|Gomez, Jose|Matsuyama, Shigemi|Chakrabarti, Amitabha|Agarwal, Munna L|Agarwal, Anju|Agarwal, Mukesh K|Wald, David N
PMID: 20133503
Journal: Appl Immunohistochem Mol Morphol. 2010 Mar;18(2):128-36.
Title: The prognostic value of p73 overexpression in colorectal carcinoma: a clinicopathologic, immunohistochemical, and statistical study of 204 patients.
Author: Toumi, Amira Arfaoui|El Hadj, Olfa El Amine|Ben Mahmoud, Lilia Kriaa|Ben Hmida, Abd El Majid|Chaar, Ines|Gharbi, Lasaad|Mzabi, Sabeh|Bouraoui, Saadia
PMID: 19956069
Journal: FASEB J. 2010 Sep;24(9):3360-9.
Title: Intake of grape-derived polyphenols reduces C26 tumor growth by inhibiting angiogenesis and inducing apoptosis.
Author: Walter, Allison|Etienne-Selloum, Nelly|Brasse, David|Khallouf, Hadeel|Bronner, Christian|Rio, Marie-Christine|Beretz, Alain|Schini-Kerth, Valerie B
PMID: 20442318
Journal: Apoptosis. 2011 Jan;16(1):35-44.
Title: Mdm2 inhibition induces apoptosis in p53 deficient human colon cancer cells by activating p73- and E2F1-mediated expression of PUMA and Siva-1.
Author: Ray, Ramesh M|Bhattacharya, Sujoy|Johnson, Leonard R
PMID: 20812030
Journal: Oncol Rep. 2011 Jan;25(1):167-72.
Title: Polymorphisms in genes involved in folate metabolism and plasma DNA methylation in colorectal cancer patients.
Author: Kim, Jong Woo|Park, Hye Mi|Choi, Young-Kook|Chong, So Young|Oh, Doyeun|Kim, Nam Keun
PMID: 21109973
Journal: Oncol Rep. 2011 May;25(5):1297-306.
Title: CDC25A, VAV1, TP73, BRCA1 and ZAP70 gene overexpression correlates with radiation response in colorectal cancer.
Author: Huang, Ming-Yii|Wang, Jaw-Yuan|Chang, Hui-Jen|Kuo, Chia-Wei|Tok, Teck-Siang|Lin, Shiu-Ru
PMID: 21344162
Journal: BMC Cancer. 2011 Mar 1;11:89.
Title: Endosialin expression in relation to clinicopathological and biological variables in rectal cancers with a Swedish clinical trial of preoperative radiotherapy.
Author: Zhang, Zhi-Yong|Zhang, Hong|Adell, Gunnar|Sun, Xiao-Feng
PMID: 21362178
Journal: Mutagenesis. 2011 Jul;26(4):573-81.
Title: p73 G4C14-A4T14 polymorphism and cancer risk: a meta-analysis based on 27 case-control studies.
Author: Liu, Fei|Liu, Liu|Li, Bo|Wei, Yong-Gang|Yan, Lv-Nan|Wen, Tian-Fu|Xu, Ming-Qing|Wang, Wen-Tao|Yang, Jia-Yin
PMID: 21502193
Journal: Gene. 2011 Sep 15;484(1-2):42-6.
Title: Relationship between TP73 polymorphism (G4C14-A4T14) and cancer risk: a meta-analysis based on literatures.
Author: Yu, Xiao-Jia|Fang, Fang|Xie, Jun
PMID: 21672615
Journal: Clin Cancer Res. 2011 Sep 15;17(18):6029-39.
Title: Prognostic impact of DeltaTAp73 isoform levels and their target genes in colon cancer patients.
Author: Soldevilla, Beatriz|Diaz, Raquel|Silva, Javier|Campos-Martin, Yolanda|Munoz, Concepcion|Garcia, Vanesa|Garcia, Jose M|Pena, Cristina|Herrera, Mercedes|Rodriguez, Marta|Gomez, Irene|Mohamed, Nagat|Marques, Margarita M|Bonilla, Felix|Dominguez, Gemma
PMID: 21807636
Journal: Radiol Oncol. 2011 Dec;45(4):279-84.
Title: Expression of NF-kappaB p65 phosphorylated at serine-536 in rectal cancer with or without preoperative radiotherapy.
Author: Lewander, Andreas|Gao, Jinfang|Adell, Gunnar|Zhang, Hong|Sun, Xiao-Feng
PMID: 22933966
Journal: Mol Biol Rep. 2012 Feb;39(2):1731-8.
Title: Combined analysis of the association between p73 G4C14-to-A4T14 polymorphisms and cancer risk.
Author: Wang, Lan|Gao, Rui|Yu, Long
PMID: 21617940
Journal: J Transl Med. 2012 May 29;10:109.
Title: Expression of AEG-1 mRNA and protein in colorectal cancer patients and colon cancer cell lines.
Author: Gnosa, Sebastian|Shen, Yang-Mei|Wang, Chao-Jie|Zhang, Hong|Stratmann, Johannes|Arbman, Gunnar|Sun, Xiao-Feng
PMID: 22643064
Journal: J Biomed Sci. 2012 Mar 30;19:35.
Title: STI571 reduces TRAIL-induced apoptosis in colon cancer cells: c-Abl activation by the death receptor leads to stress kinase-dependent cell death.
Author: Huang, Duen-Yi|Chao, Yee|Tai, Ming-Hui|Yu, Yang-Hao|Lin, Wan-Wan
PMID: 22462553
Journal: J Pathol. 2012 Dec;228(4):471-81.
Title: Cellular apoptosis susceptibility (chromosome segregation 1-like, CSE1L) gene is a key regulator of apoptosis, migration and invasion in colorectal cancer.
Author: Alnabulsi, Ayham|Agouni, Abdelali|Mitra, Suman|Garcia-Murillas, Isaac|Carpenter, Brian|Bird, Steve|Murray, Graeme I
PMID: 22450763
Journal: Apoptosis. 2012 Mar;17(3):236-47.
Title: Pleomorphic adenoma gene-like 2 regulates expression of the p53 family member, p73, and induces cell cycle block and apoptosis in human promonocytic U937 cells.
Author: Hanks, Tracey S|Gauss, Katherine A
PMID: 22076304
Journal: DNA Cell Biol. 2012 Feb;31(2):230-7.
Title: Association between the p73 exon 2 G4C14-to-A4T14 polymorphism and cancer risk: a meta-analysis.
Author: Hu, Yi|Jiang, Lan|Zheng, Jian|You, Yonghe|Zhou, Yifeng|Jiao, Shunchang
PMID: 22011187
Journal: Mol Carcinog. 2012 Aug;51(8):628-35.
Title: Effects of DeltaNp73beta on cisplatin treatment in colon cancer cells.
Author: Loof, Jasmine|Pfeifer, Daniella|Ding, Zhenyu|Sun, Xiao-Feng|Zhang, Hong
PMID: 21837762
Journal: Br J Pharmacol. 2013 Apr;168(8):1989-99.
Title: Regulation of carboxylesterase-2 expression by p53 family proteins and enhanced anti-cancer activities among 5-fluorouracil, irinotecan and doxazolidine prodrug.
Author: Xiao, Da|Yang, Dongfang|Guo, Liangran|Lu, Wei|Charpentier, Margaret|Yan, Bingfang
PMID: 23373735
Journal: J Inorg Biochem. 2013 Oct;127:24-38.
Title: The influence of R substituents in triphenylphosphinegold(I) carbonimidothioates, Ph3PAu[SC(OR)=NPh] (R=Me, Et and iPr), upon in vitro cytotoxicity against the HT-29 colon cancer cell line and upon apoptotic pathways.
Author: Yeo, Chien Ing|Ooi, Kah Kooi|Akim, Abdah Md|Ang, Kok Pian|Fairuz, Zainal Abidin|Halim, Siti Nadiah Binti Abdul|Ng, Seik Weng|Seng, Hoi-Ling|Tiekink, Edward R T
PMID: 23850666
Journal: J Biol Chem. 2013 Dec 13;288(50):35637-50.
Title: The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.
Author: Lu, Li|Hu, Shaohua|Wei, Rongfei|Qiu, Xiao|Lu, Kefeng|Fu, Yesheng|Li, Hongchang|Xing, Guichun|Li, Dong|Peng, Ruiyun|He, Fuchu|Zhang, Lingqiang
PMID: 24163370
Journal: Turk J Med Sci. 2014;44(5):875-82.
Title: Expression and clinical implications of P53, P63, and P73 protein in malignant tumor of the parotid gland.
Author: Yong, Mei|Yang, Ling|Suyila, Qimuge|Han, Wenyan|Yuan, Hongwei|Zhao, Cheng|Su, Xiulan
PMID: 25539561
Journal: Apoptosis. 2014 Jan;19(1):149-64.
Title: Mahanine synergistically enhances cytotoxicity of 5-fluorouracil through ROS-mediated activation of PTEN and p53/p73 in colon carcinoma.
Author: Das, Ranjita|Bhattacharya, Kaushik|Sarkar, Sayantani|Samanta, Suman Kumar|Pal, Bikas C|Mandal, Chitra
PMID: 24052409
Journal: Biochem Biophys Res Commun. 2014 Apr 4;446(2):596-601.
Title: T-oligo as an anticancer agent in colorectal cancer.
Author: Wojdyla, Luke|Stone, Amanda L|Sethakorn, Nan|Uppada, Srijayaprakash B|Devito, Joseph T|Bissonnette, Marc|Puri, Neelu
PMID: 24632202
Journal: Histol Histopathol. 2014 Feb;29(2):207-16.
Title: Differential expression of p53 family proteins in colorectal adenomas and carcinomas: Prognostic and predictive values.
Author: Bahnassy, Abeer A|Zekri, Abdel-Rahman N|Salem, Salem E|Abou-Bakr, Amany A|Sakr, Mona A|Abdel-Samiaa, Ayman G|Al-Bradei, Manal
PMID: 23996743
Journal: Cancer Res. 2014 Feb 15;74(4):1153-65.
Title: Prodigiosin rescues deficient p53 signaling and antitumor effects via upregulating p73 and disrupting its interaction with mutant p53.
Author: Hong, Bo|Prabhu, Varun V|Zhang, Shengliang|van den Heuvel, A Pieter J|Dicker, David T|Kopelovich, Levy|El-Deiry, Wafik S
PMID: 24247721
Journal: J Biol Inorg Chem. 2015 Jul;20(5):855-73.
Title: Phosphanegold(I) thiolates, Ph3PAu[SC(OR)=NC 6H 4Me-4] for R = Me, Et and iPr, induce apoptosis, cell cycle arrest and inhibit cell invasion of HT-29 colon cancer cells through modulation of the nuclear factor-kappaB activation pathway and ubiquitination.
Author: Ooi, Kah Kooi|Yeo, Chien Ing|Ang, Kok-Pian|Akim, Abdah Md|Cheah, Yoke-Kqueen|Halim, Siti Nadiah Abdul|Seng, Hoi-Ling|Tiekink, Edward R T
PMID: 26003312
Journal: Clin Cancer Res. 2015 Oct 1;21(19):4398-409.
Title: beta-Cryptoxanthin Synergistically Enhances the Antitumoral Activity of Oxaliplatin through DeltaNP73 Negative Regulation in Colon Cancer.
Author: San Millan, Coral|Soldevilla, Beatriz|Martin, Paloma|Gil-Calderon, Beatriz|Compte, Marta|Perez-Sacristan, Belen|Donoso, Encarnacion|Pena, Cristina|Romero, Jesus|Granado-Lorencio, Fernando|Bonilla, Felix|Dominguez, Gemma
PMID: 26023082
Journal: PLoS One. 2015 Jun 1;10(6):e0126645.
Title: Phylogenetically Distant Viruses Use the Same BH3-Only Protein Puma to Trigger Bax/Bak-Dependent Apoptosis of Infected Mouse and Human Cells.
Author: Papaianni, Emanuela|El Maadidi, Souhayla|Schejtman, Andrea|Neumann, Simon|Maurer, Ulrich|Marino-Merlo, Francesca|Mastino, Antonio|Borner, Christoph
PMID: 26030884
Journal: Int J Hyperthermia. 2015;31(5):464-75.
Title: Hyperthermia effects on Hsp27 and Hsp72 associations with mismatch repair (MMR) proteins and cisplatin toxicity in MMR-deficient/proficient colon cancer cell lines.
Author: Sottile, Mayra L|Losinno, Antonella D|Fanelli, Mariel A|Cuello-Carrion, F Dario|Montt-Guevara, M Magdalena|Vargas-Roig, Laura M|Nadin, Silvina B
PMID: 26043026
Journal: Cancer Res. 2015 Sep 15;75(18):3842-52.
Title: Small-Molecule NSC59984 Restores p53 Pathway Signaling and Antitumor Effects against Colorectal Cancer via p73 Activation and Degradation of Mutant p53.
Author: Zhang, Shengliang|Zhou, Lanlan|Hong, Bo|van den Heuvel, A Pieter J|Prabhu, Varun V|Warfel, Noel A|Kline, Christina Leah B|Dicker, David T|Kopelovich, Levy|El-Deiry, Wafik S
PMID: 26294215
Journal: Cancer Res. 2016 Apr 1;76(7):1989-99.
Title: Small-Molecule Prodigiosin Restores p53 Tumor Suppressor Activity in Chemoresistant Colorectal Cancer Stem Cells via c-Jun-Mediated DeltaNp73 Inhibition and p73 Activation.
Author: Prabhu, Varun V|Hong, Bo|Allen, Joshua E|Zhang, Shengliang|Lulla, Amriti R|Dicker, David T|El-Deiry, Wafik S
PMID: 26759239
Journal: Sci Rep. 2016 Sep 13;6:32979.
Title: Crocetin exploits p53-induced death domain (PIDD) and FAS-associated death domain (FADD) proteins to induce apoptosis in colorectal cancer.
Author: Ray, Pallab|Guha, Deblina|Chakraborty, Juni|Banerjee, Shuvomoy|Adhikary, Arghya|Chakraborty, Samik|Das, Tanya|Sa, Gaurisankar
PMID: 27622714
Journal: Folia Histochem Cytobiol. 2016;54(3):166-170.
Title: Decreased expression of p73 in colorectal cancer.
Author: Kotulak, Anna|Wronska, Agata|Kobiela, Jaroslaw|Godlewski, Janusz|Stanislawowski, Marcin|Wierzbicki, Piotr
PMID: 27654017
Journal: Klin Onkol. 2017 Spring;30(Supplementum1):159-162.
Title: [Application of PLA Method for Detection of p53/p63/p73 Complexes in Situ in Tumour Cells and Tumour Tissue].
Author: Hrabal, V|Nekulova, M|Nenutil, R|Holcakova, J|Coates, P J|Vojtesek, B
PMID: 28471195
Journal: BMC Complement Altern Med. 2017 Dec 19;17(1):539.
Title: Cytotoxic, antioxidative, genotoxic and antigenotoxic effects of Horchata, beverage of South Ecuador.
Author: Bailon-Moscoso, Natalia|Tinitana, Fani|Martinez-Espinosa, Ruth|Jaramillo-Velez, Andrea|Palacio-Arpi, Alejandra|Aguilar-Hernandez, Jessica|Romero-Benavides, Juan Carlos
PMID: 29258490
Journal: Onco Targets Ther. 2017 Nov 3;10:5281-5288.
Title: PUMA mediates the anti-cancer effect of osimertinib in colon cancer cells.
Author: Guo, Lingchuan|Huang, Shan|Wang, Xinwei
PMID: 29138581
Journal: Mol Med Rep. 2017 Nov;16(5):7796-7804.
Title: Sulforaphane induces p53deficient SW480 cell apoptosis via the ROSMAPK signaling pathway.
Author: Lan, Hai|Yuan, Hongyin|Lin, Congyao
PMID: 28944886
Journal: Sci Rep. 2017 Jul 14;7(1):5423.
Title: The essential role of TAp73 in bortezomib-induced apoptosis in p53-deficient colorectal cancer cells.
Author: Dabiri, Yasamin|Kalman, Sara|Gurth, Clara-Marie|Kim, Jee Young|Mayer, Viola|Cheng, Xinlai
PMID: 28710427
Journal: FEBS J. 2017 Apr;284(8):1233-1245.
Title: Catalytic competence, structure and stability of the cancer-associated R139W variant of the human NAD(P)H:quinone oxidoreductase 1 (NQO1).
Author: Lienhart, Wolf-Dieter|Strandback, Emilia|Gudipati, Venugopal|Koch, Karin|Binter, Alexandra|Uhl, Michael K|Rantasa, David M|Bourgeois, Benjamin|Madl, Tobias|Zangger, Klaus|Gruber, Karl|Macheroux, Peter
PMID: 28236663
Journal: Cancer Lett. 2018 Feb 28;415:106-116.
Title: TAp73 inhibits cell invasion and migration by directly activating KAI1 expression in colorectal carcinoma.
Author: Bae, Woo-Kyun|Hong, Chang-Soo|Park, Mi-Ra|Sun, Eun-Gene|Lee, Ji-Hee|Kang, Keunsoo|Ryu, Kyung-Hyun|Shim, Hyun-Jeong|Hwang, Jun-Eul|Cho, Sang-Hee|Chung, Ik-Joo
PMID: 29222041
Journal: Oncogene. 2018 May 14. pii: 10.1038/s41388-018-0289-x.
Title: Restoring PUMA induction overcomes KRAS-mediated resistance to anti-EGFR antibodies in colorectal cancer.
Author: Knickelbein, Kyle|Tong, Jingshan|Chen, Dongshi|Wang, Yi-Jun|Misale, Sandra|Bardelli, Alberto|Yu, Jian|Zhang, Lin
PMID: 29755130
Journal: J Cancer. 2018 May 22;9(11):2046-2053.
Title: A Study on Effect of Oxaliplatin in MicroRNA Expression in Human Colon Cancer.
Author: Evert, Jasmine|Pathak, Surajit|Sun, Xiao-Feng|Zhang, Hong
PMID: 29896290
Journal: BMC Cancer. 2018 Jun 27;18(1):695.
Title: Gene promoter and exon DNA methylation changes in colon cancer development - mRNA expression and tumor mutation alterations.
Author: Molnar, Bela|Galamb, Orsolya|Peterfia, Balint|Wichmann, Barnabas|Csabai, Istvan|Bodor, Andras|Kalmar, Alexandra|Szigeti, Krisztina Andrea|Bartak, Barbara Kinga|Nagy, Zsofia Brigitta|Valcz, Gabor|Patai, Arpad V|Igaz, Peter|Tulassay, Zsolt
PMID: 29945573
Journal: Cancer Biomark. 2018;23(1):145-156.
Title: Long non-coding RNA TP73-AS1 sponges miR-194 to promote colorectal cancer cell proliferation, migration and invasion via up-regulating TGFalpha.
Author: Cai, Yu|Yan, Pu|Zhang, Ge|Yang, Wenqi|Wang, Haiping|Cheng, Xiaohu
PMID: 30010111
Journal: Invest New Drugs. 2018 Sep 6. pii: 10.1007/s10637-018-0663-0.
Title: Phase I study combining the aurora kinase a inhibitor alisertib with mFOLFOX in gastrointestinal cancer.
Author: Goff, Laura W|Azad, Nilo|Stein, Stacey|Whisenant, Jennifer G|Koyama, Tatsuki|Vaishampayan, Ulka|Hochster, Howard|Connolly, Roisin|Weise, Amy|LoRusso, Patricia M|Salaria, Safia N|El-Rifai, Wael|Berlin, Jordan D
PMID: 30191522