Primary Site >> Colorectal Cancer

Gene >> TP53BP1

Journal: Adv Genet. 2005;54:235-55.
Title: Cancer-specific gene therapy.
Author: Lo, Hui-Wen|Day, Chi-Ping|Hung, Mien-Chie
PMID: 16096014
Journal: Biochem Biophys Res Commun. 2008 Nov 21;376(3):509-13.
Title: Characterization of a cancer cell line that expresses a splicing variant form of 53BP1: separation of checkpoint and repair functions in 53BP1.
Author: Iwabuchi, Kuniyoshi|Matsui, Tadashi|Hashimoto, Mitsumasa|Matsumoto, Yoshihisa|Kurihara, Takayuki|Date, Takayasu
PMID: 18804090
Journal: J Biol Chem. 2011 Apr 8;286(14):12157-65.
Title: MSH3 mediates sensitization of colorectal cancer cells to cisplatin, oxaliplatin, and a poly(ADP-ribose) polymerase inhibitor.
Author: Takahashi, Masanobu|Koi, Minoru|Balaguer, Francesc|Boland, C Richard|Goel, Ajay
PMID: 21285347
Journal: Liver Int. 2011 Apr;31(4):561-71.
Title: Aflatoxin genotoxicity is associated with a defective DNA damage response bypassing p53 activation.
Author: Gursoy-Yuzugullu, Ozge|Yuzugullu, Haluk|Yilmaz, Mustafa|Ozturk, Mehmet
PMID: 21382167
Journal: Hum Pathol. 2013 Jun;44(6):1038-46.
Title: Alteration of the DNA damage response in colorectal tumor progression.
Author: Takabayashi, Hiroaki|Wakai, Toshifumi|Ajioka, Yoichi|Korita, Pavel V|Yamaguchi, Naoyuki
PMID: 23332927
Journal: PLoS One. 2013 May 28;8(5):e65369.
Title: MSH3 mismatch repair protein regulates sensitivity to cytotoxic drugs and a histone deacetylase inhibitor in human colon carcinoma cells.
Author: Park, Jae Myung|Huang, Shengbing|Tougeron, David|Sinicrope, Frank A
PMID: 23724141
Journal: Mol Cancer. 2013 Aug 6;12:89.
Title: Kruppel-like factor 4 regulates genetic stability in mouse embryonic fibroblasts.
Author: El-Karim, Enas A|Hagos, Engda G|Ghaleb, Amr M|Yu, Bing|Yang, Vincent W
PMID: 23919723
Journal: Radiother Oncol. 2014 Feb;110(2):355-61.
Title: PLK1-inhibition can cause radiosensitization or radioresistance dependent on the treatment schedule.
Author: Lund-Andersen, Christin|Patzke, Sebastian|Nahse-Kumpf, Viola|Syljuasen, Randi G
PMID: 24502970
Journal: PLoS One. 2014 Jun 23;9(6):e100819.
Title: Beclin 1 and UVRAG confer protection from radiation-induced DNA damage and maintain centrosome stability in colorectal cancer cells.
Author: Park, Jae Myung|Tougeron, David|Huang, Shengbing|Okamoto, Koichi|Sinicrope, Frank A
PMID: 24956373
Journal: BMC Cancer. 2015 Nov 6;15:856.
Title: A prospective study on histone gamma-H2AX and 53BP1 foci expression in rectal carcinoma patients: correlation with radiation therapy-induced outcome.
Author: Djuzenova, Cholpon S|Zimmermann, Marcus|Katzer, Astrid|Fiedler, Vanessa|Distel, Luitpold V|Gasser, Martin|Waaga-Gasser, Anna-Maria|Flentje, Michael|Polat, Bulent
PMID: 26541290
Journal: Radiat Oncol. 2015 Sep 17;10:198.
Title: The SMAC mimetic BV6 sensitizes colorectal cancer cells to ionizing radiation by interfering with DNA repair processes and enhancing apoptosis.
Author: Hehlgans, Stephanie|Oppermann, Julius|Reichert, Sebastian|Fulda, Simone|Rodel, Claus|Rodel, Franz
PMID: 26383618
Journal: Int J Clin Exp Pathol. 2015 Jun 1;8(6):6070-82. eCollection 2015.
Title: Expression of DNA damage checkpoint 53BP1 is correlated with prognosis, cell proliferation and apoptosis in colorectal cancer.
Author: Bi, Jianping|Huang, Ai|Liu, Tao|Zhang, Tao|Ma, Hong
PMID: 26261485
Journal: Int J Mol Sci. 2015 Jun 29;16(7):14655-68.
Title: Echinacoside Induces Apoptosis in Human SW480 Colorectal Cancer Cells by Induction of Oxidative DNA Damages.
Author: Dong, Liwei|Yu, Debin|Wu, Nuoting|Wang, Hongge|Niu, Jiajing|Wang, Ye|Zou, Zhihua
PMID: 26132569
Journal: Oncol Rep. 2015 Mar;33(3):1161-70.
Title: Icotinib hydrochloride enhances the effect of radiotherapy by affecting DNA repair in colorectal cancer cells.
Author: Ma, Hong|Bi, Jianping|Liu, Tao|Ke, Yang|Zhang, Sheng|Zhang, Tao
PMID: 25572529
Journal: Mol Cancer Ther. 2015 Feb;14(2):597-607.
Title: Targeting BRG1 chromatin remodeler via its bromodomain for enhanced tumor cell radiosensitivity in vitro and in vivo.
Author: Kwon, Su-Jung|Lee, Seul-Ki|Na, Juri|Lee, Shin-Ai|Lee, Han-Sae|Park, Ji-Hye|Chung, June-Key|Youn, Hyewon|Kwon, Jongbum
PMID: 25504753
Journal: Oncotarget. 2016 Feb 2;7(5):6074-87.
Title: Lanatoside C suppressed colorectal cancer cell growth by inducing mitochondrial dysfunction and increased radiation sensitivity by impairing DNA damage repair.
Author: Kang, Mi Ae|Kim, Mi-Sook|Kim, Wonwoo|Um, Jee-Hyun|Shin, Young-Joo|Song, Jie-Young|Jeong, Jae-Hoon
PMID: 26756216
Journal: Mol Biol Cell. 2016 Apr 15;27(8):1346-57.
Title: RCC1-dependent activation of Ran accelerates cell cycle and DNA repair, inhibiting DNA damage-induced cell senescence.
Author: Cekan, Pavol|Hasegawa, Keisuke|Pan, Yu|Tubman, Emily|Odde, David|Chen, Jin-Qiu|Herrmann, Michelle A|Kumar, Sheetal|Kalab, Petr
PMID: 26864624
Journal: Cell Mol Life Sci. 2016 Dec;73(23):4383-4395.
Title: Absent in melanoma 2 proteins in the development of cancer.
Author: Choubey, Divaker
PMID: 27328971
Journal: Int J Oncol. 2016 Oct;49(4):1600-8.
Title: Deficiency of 53BP1 inhibits the radiosensitivity of colorectal cancer.
Author: Xiao, Yong|Zheng, Xiumei|Huang, Ai|Liu, Tao|Zhang, Tao|Ma, Hong
PMID: 27499037
Journal: Oncotarget. 2016 Nov 22;7(47):77926-77936.
Title: Targeting Enox1 in tumor stroma increases the efficacy of fractionated radiotherapy.
Author: Smith, Clayton A|Mont, Stacey|Traver, Geri|Sekhar, Konjeti R|Crooks, Peter A|Freeman, Michael L
PMID: 27788492
Journal: World J Gastroenterol. 2016 Dec 28;22(48):10680-10686.
Title: Efficiency of olaparib in colorectal cancer patients with an alteration of the homologous repair protein.
Author: Ghiringhelli, Francois|Richard, Corentin|Chevrier, Sandy|Vegran, Frederique|Boidot, Romain
PMID: 28082821
Journal: J Cancer Res Clin Oncol. 2017 Mar;143(3):419-431.
Title: 53BP1 loss induces chemoresistance of colorectal cancer cells to 5-fluorouracil by inhibiting the ATM-CHK2-P53 pathway.
Author: Yao, Jing|Huang, Ai|Zheng, Xiumei|Liu, Tao|Lin, Zhenyu|Zhang, Sheng|Yang, Qin|Zhang, Tao|Ma, Hong
PMID: 27838786
Journal: Cancer Lett. 2017 May 1;393:103-112.
Title: Silencing of the mRNA-binding protein HuR increases the sensitivity of colorectal cancer cells to ionizing radiation through upregulation of caspase-2.
Author: Badawi, Amel|Hehlgans, Stephanie|Pfeilschifter, Josef|Rodel, Franz|Eberhardt, Wolfgang
PMID: 28219770
Journal: PLoS Genet. 2017 Aug 14;13(8):e1006942.
Title: A 'synthetic-sickness' screen for senescence re-engagement targets in mutant cancer backgrounds.
Author: Cairney, Claire J|Godwin, Lauren S|Bilsland, Alan E|Burns, Sharon|Stevenson, Katrina H|McGarry, Lynn|Revie, John|Moore, Jon D|Wiggins, Ceri M|Collinson, Rebecca S|Mudd, Clare|Tsonou, Elpida|Sadaie, Mahito|Bennett, Dorothy C|Narita, Masashi|Torrance, Chris
PMID: 28806777
Journal: Pathol Oncol Res. 2018 Jul;24(3):617-622.
Title: Frameshift Mutations in Repeat Sequences of ANK3, HACD4, TCP10L, TP53BP1, MFN1, LCMT2, RNMT, TRMT6, METTL8 and METTL16 Genes in Colon Cancers.
Author: Yeon, Su Yeon|Jo, Yun Sol|Choi, Eun Ji|Kim, Min Sung|Yoo, Nam Jin|Lee, Sug Hyung
PMID: 28803425
Journal: Int J Radiat Biol. 2018 Apr;94(4):327-334.
Title: 53BP1 loss suppresses the radiosensitizing effect of icotinib hydrochloride in colorectal cancer cells.
Author: Huang, Ai|Yao, Jing|Liu, Tao|Lin, Zhenyu|Zhang, Sheng|Zhang, Tao|Ma, Hong
PMID: 29388453
Journal: Aging (Albany NY). 2018 Aug 22;10(8):2062-2078.
Title: LncRNA BANCR promotes tumorigenesis and enhances adriamycin resistance in colorectal cancer.
Author: Ma, Siping|Yang, Dongxiang|Liu, Yanlong|Wang, Yongpeng|Lin, Tao|Li, Yanxi|Yang, Shihua|Zhang, Wanchuan|Zhang, Rui
PMID: 30144787
Journal: Mol Cancer Res. 2018 Sep 10. pii: 1541-7786.MCR-18-0650.
Title: Repurposing of mTOR Complex inhibitors Attenuates MCL-1 and sensitizes to PARP inhibition.
Author: Mattoo, Abid R|Joun, Alex|Jessup, J Milburn
PMID: 30201826