Primary Site >> Colorectal Cancer

Gene >> TOP2A

Journal: Oncol Res. 1995;7(12):583-90.
Title: Glucose-regulated stresses confer resistance to VP-16 in human cancer cells through a decreased expression of DNA topoisomerase II.
Author: Yun, J|Tomida, A|Nagata, K|Tsuruo, T
PMID: 8704275
Journal: J Clin Pathol. 2007 Jul;60(7):768-72. Epub 2006 Aug 1.
Title: HER2, TOP2A, CCND1, EGFR and C-MYC oncogene amplification in colorectal cancer.
Author: Al-Kuraya, Khawla|Novotny, Hedvika|Bavi, Prashant|Siraj, Abdul K|Uddin, Shahab|Ezzat, Adnan|Sanea, Nasser Al|Al-Dayel, Fouad|Al-Mana, Hadeel|Sheikh, Salwa S|Mirlacher, Martina|Tapia, Coya|Simon, Ronald|Sauter, Guido|Terracciano, Luigi|Tornillo, Luigi
PMID: 16882699
Journal: Cancer Res. 2007 Oct 15;67(20):9971-9.
Title: Batracylin (NSC 320846), a dual inhibitor of DNA topoisomerases I and II induces histone gamma-H2AX as a biomarker of DNA damage.
Author: Rao, V Ashutosh|Agama, Keli|Holbeck, Susan|Pommier, Yves
PMID: 17942930
Journal: Cancer Lett. 2009 Apr 18;276(2):228-38.
Title: Increased topoisomerase IIalpha expression in colorectal cancer is associated with advanced disease and chemotherapeutic resistance via inhibition of apoptosis.
Author: Coss, Alan|Tosetto, Miriam|Fox, Edward J|Sapetto-Rebow, Beata|Gorman, Sheeona|Kennedy, Breandan N|Lloyd, Andrew T|Hyland, John M|O'Donoghue, Diarmuid P|Sheahan, Kieran|Leahy, Dermot T|Mulcahy, Hugh E|O'Sullivan, Jacintha N
PMID: 19111388
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2010 Aug;30(8):1959-61, 1964.
Title: [Expression of topoisomerase II alpha in human colorectal carcinoma and its significance].
Author: Yang, Fa-da|Jia, Zhang-lin
PMID: 20813715
Journal: J Nutr Metab. 2012;2012:351796.
Title: Microarray Analyses of Genes Differentially Expressed by Diet (Black Beans and Soy Flour) during Azoxymethane-Induced Colon Carcinogenesis in Rats.
Author: Rondini, Elizabeth A|Bennink, Maurice R
PMID: 22496968
Journal: Scand J Gastroenterol. 2013 Dec;48(12):1436-43.
Title: Underpinning the repurposing of anthracyclines towards colorectal cancer: assessment of topoisomerase II alpha gene copy number alterations in colorectal cancer.
Author: Nygard, Sune Boris|Christensen, Ib Jarle|Smith, David Hersi|Nielsen, Signe Lykke|Jensen, Niels Frank|Nielsen, Hans Jorgen|Vainer, Ben|Brunner, Nils
PMID: 24138107
Journal: BMC Genomics. 2014 Mar 13;15:190.
Title: Immunomic, genomic and transcriptomic characterization of CT26 colorectal carcinoma.
Author: Castle, John C|Loewer, Martin|Boegel, Sebastian|de Graaf, Jos|Bender, Christian|Tadmor, Arbel D|Boisguerin, Valesca|Bukur, Thomas|Sorn, Patrick|Paret, Claudia|Diken, Mustafa|Kreiter, Sebastian|Tureci, Ozlem|Sahin, Ugur
PMID: 24621249
Journal: Exp Mol Pathol. 2015 Jun;98(3):375-81.
Title: Tissue-specific selection of optimal reference genes for expression analysis of anti-cancer drug-related genes in tumor samples using quantitative real-time RT-PCR.
Author: Wang, Huijuan|Yang, Bobo|Geng, Tingting|Li, Bin|Dai, Penggao|Chen, Chao
PMID: 25445497
Journal: Mol Oncol. 2015 Jun;9(6):1207-17.
Title: Topoisomerase-1 and -2A gene copy numbers are elevated in mismatch repair-proficient colorectal cancers.
Author: Sonderstrup, Ida Marie Heeholm|Nygard, Sune Boris|Poulsen, Tim Svenstrup|Linnemann, Dorte|Stenvang, Jan|Nielsen, Hans Jorgen|Bartek, Jiri|Brunner, Nils|Norgaard, Peter|Riis, Lene
PMID: 25777966
Journal: Nucleic Acids Res. 2015 Jul 27;43(13):6257-69.
Title: Context-specific role of SOX9 in NF-Y mediated gene regulation in colorectal cancer cells.
Author: Shi, Zhongcheng|Chiang, Chi-I|Labhart, Paul|Zhao, Yanling|Yang, Jianhua|Mistretta, Toni-Ann|Henning, Susan J|Maity, Sankar N|Mori-Akiyama, Yuko
PMID: 26040697
Journal: BMC Cancer. 2016 Feb 11;16:91.
Title: A phase II study of Epirubicin in oxaliplatin-resistant patients with metastatic colorectal cancer and TOP2A gene amplification.
Author: Tarpgaard, Line S|Qvortrup, Camilla|Nygard, Sune B|Nielsen, Signe L|Andersen, Diana R|Jensen, Niels Frank|Stenvang, Jan|Detlefsen, Sonke|Brunner, Nils|Pfeiffer, Per
PMID: 26867764
Journal: Medicine (Baltimore). 2017 Jan;96(1):e5845.
Title: ZNF148 modulates TOP2A expression and cell proliferation via ceRNA regulatory mechanism in colorectal cancer.
Author: Gao, Xian Hua|Li, Juan|Liu, Yan|Liu, Qi Zhi|Hao, Li Qiang|Liu, Lian Jie|Zhang, Wei
PMID: 28072746
Journal: Anticancer Res. 2018 Apr;38(4):2235-2240.
Title: Racial Disparities in the Molecular Landscape of Cancer.
Author: Heath, Elisabeth I|Lynce, Filipa|Xiu, Joanne|Ellerbrock, Angela|Reddy, Sandeep K|Obeid, Elias|Liu, Stephen V|Bollig-Fischer, Aliccia|Separovic, Duska|Vanderwalde, Ari
PMID: 29599344
Journal: Dis Markers. 2018 Jan 30;2018:3452739.
Title: Identification of Common Genes Refers to Colorectal Carcinogenesis with Paired Cancer and Noncancer Samples.
Author: Zhang, Lihua|Yang, Yonglong|Cheng, Lin|Cheng, Yu|Zhou, Hong-Hao|Tan, Zhi-Rong
PMID: 29651323
Journal: J Cell Biochem. 2018 Sep;119(9):7256-7263.
Title: Proliferation and invasion of colon cancer cells are suppressed by knockdown of TOP2A.
Author: Zhang, Rui|Xu, Jian|Zhao, Jian|Bai, Jing H
PMID: 29761838