Primary Site >> Colorectal Cancer
Gene >> TOP2A
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Ref: Glucose-regulated stresses confer resistance to VP-16 in human cancer cells through a decreased expression of DNA topoisomerase II. PMID: 8704275 |
Ref: HER2, TOP2A, CCND1, EGFR and C-MYC oncogene amplification in colorectal cancer. PMID: 16882699 Ref: Batracylin (NSC 320846), a dual inhibitor of DNA topoisomerases I and II induces histone gamma-H2AX as a biomarker of DNA damage. PMID: 17942930 |
Ref: Increased topoisomerase IIalpha expression in colorectal cancer is associated with advanced disease and chemotherapeutic resistance via inhibition of apoptosis. PMID: 19111388 |
Ref: [Expression of topoisomerase II alpha in human colorectal carcinoma and its significance]. PMID: 20813715 |
Ref: Microarray Analyses of Genes Differentially Expressed by Diet (Black Beans and Soy Flour) during Azoxymethane-Induced Colon Carcinogenesis in Rats. PMID: 22496968 |
Ref: Underpinning the repurposing of anthracyclines towards colorectal cancer: assessment of topoisomerase II alpha gene copy number alterations in colorectal cancer. PMID: 24138107 |
Ref: Immunomic, genomic and transcriptomic characterization of CT26 colorectal carcinoma. PMID: 24621249 |
Ref: Tissue-specific selection of optimal reference genes for expression analysis of anti-cancer drug-related genes in tumor samples using quantitative real-time RT-PCR. PMID: 25445497 Ref: Topoisomerase-1 and -2A gene copy numbers are elevated in mismatch repair-proficient colorectal cancers. PMID: 25777966 Ref: Context-specific role of SOX9 in NF-Y mediated gene regulation in colorectal cancer cells. PMID: 26040697 |
Ref: A phase II study of Epirubicin in oxaliplatin-resistant patients with metastatic colorectal cancer and TOP2A gene amplification. PMID: 26867764 |
Ref: ZNF148 modulates TOP2A expression and cell proliferation via ceRNA regulatory mechanism in colorectal cancer. PMID: 28072746 |
Ref: Racial Disparities in the Molecular Landscape of Cancer. PMID: 29599344 Ref: Identification of Common Genes Refers to Colorectal Carcinogenesis with Paired Cancer and Noncancer Samples. PMID: 29651323 Ref: Proliferation and invasion of colon cancer cells are suppressed by knockdown of TOP2A. PMID: 29761838 |