Primary Site >> Colorectal Cancer

Gene >> TNKS2

Journal: Cancer Immunol Immunother. 2008 Jun;57(6):871-81. Epub 2007 Nov 20.
Title: Human tankyrases are aberrantly expressed in colon tumors and contain multiple epitopes that induce humoral and cellular immune responses in cancer patients.
Author: Shebzukhov, Yuriy V|Lavrik, Inna N|Karbach, Julia|Khlgatian, Svetlana V|Koroleva, Ekaterina P|Belousov, Pavel V|Kashkin, Kirill N|Knuth, Alexander|Jager, Elke|Chi, Nai-Wen|Kuprash, Dmitry V|Nedospasov, Sergei A
PMID: 18026951
Journal: Cancer Sci. 2011 Feb;102(2):330-5.
Title: Telomerase activation without shortening of telomeric 3'-overhang is a poor prognostic factor in human colorectal cancer.
Author: Kojima, Kensaku|Hiyama, Eiso|Otani, Keiko|Ohtaki, Megu|Fukuba, Ikuko|Fukuda, Emi|Sueda, Taijiro|Hiyama, Keiko
PMID: 21108695
Journal: Hum Pathol. 2011 Sep;42(9):1289-96.
Title: Frameshift mutations of poly(adenosine diphosphate-ribose) polymerase genes in gastric and colorectal cancers with microsatellite instability.
Author: Kim, Min Sung|An, Chang Hyeok|Kim, Sung Soo|Yoo, Nam Jin|Lee, Sug Hyung
PMID: 21333322
Journal: Cancer Res. 2012 Jun 1;72(11):2822-32.
Title: A novel tankyrase inhibitor decreases canonical Wnt signaling in colon carcinoma cells and reduces tumor growth in conditional APC mutant mice.
Author: Waaler, Jo|Machon, Ondrej|Tumova, Lucie|Dinh, Huyen|Korinek, Vladimir|Wilson, Steven Ray|Paulsen, Jan Erik|Pedersen, Nina Marie|Eide, Tor J|Machonova, Olga|Gradl, Dietmar|Voronkov, Andrey|von Kries, Jens Peter|Krauss, Stefan
PMID: 22440753
Journal: J Med Chem. 2013 Dec 27;56(24):10003-15.
Title: Development of novel dual binders as potent, selective, and orally bioavailable tankyrase inhibitors.
Author: Hua, Zihao|Bregman, Howard|Buchanan, John L|Chakka, Nagasree|Guzman-Perez, Angel|Gunaydin, Hakan|Huang, Xin|Gu, Yan|Berry, Virginia|Liu, Jingzhou|Teffera, Yohannes|Huang, Liyue|Egge, Bryan|Emkey, Renee|Mullady, Erin L|Schneider, Steve|Andrews, Paul S|Acqu
PMID: 24294969
Journal: PLoS One. 2017 Jan 20;12(1):e0170508.
Title: Differential Roles of AXIN1 and AXIN2 in Tankyrase Inhibitor-Induced Formation of Degradasomes and beta-Catenin Degradation.
Author: Thorvaldsen, Tor Espen|Pedersen, Nina Marie|Wenzel, Eva Maria|Stenmark, Harald
PMID: 28107521
Journal: Cancer Chemother Pharmacol. 2018 Oct;82(4):635-647.
Title: Identification and preclinical characterization of a novel and potent poly (ADP-ribose) polymerase (PARP) inhibitor ZYTP1.
Author: Jain, Mukul R|Mohapatra, Jogeswar|Bandhyopadhyay, Debdutta|Chatterjee, Abhijit|Ghoshdastidar, Krishnarup|Patel, Dinesh|Patel, Ankit|Bhayani, Hitesh|Srivastava, Brijesh Kumar|Shedage, Sandeep A|Kadam, Pravin|Sundar, Rajesh|Patel, Harilal|Giri, Poonam|Patel
PMID: 30046848
Journal: J Biomol Struct Dyn. 2018 Sep 11:1-29.
Title: In silico insights on Tankyrase protein: a potential target for colorectal cancer.
Author: Lakshmanan, Loganathan|Muthusamy, Karthikeyan|Marshal, Jayaraj John|Kajamaideen, Afrinrilwana|Balthasar, Josephine Julia
PMID: 30204055