Primary Site >> Colorectal Cancer

Gene >> TNKS

Journal: Cancer Immunol Immunother. 2008 Jun;57(6):871-81. Epub 2007 Nov 20.
Title: Human tankyrases are aberrantly expressed in colon tumors and contain multiple epitopes that induce humoral and cellular immune responses in cancer patients.
Author: Shebzukhov, Yuriy V|Lavrik, Inna N|Karbach, Julia|Khlgatian, Svetlana V|Koroleva, Ekaterina P|Belousov, Pavel V|Kashkin, Kirill N|Knuth, Alexander|Jager, Elke|Chi, Nai-Wen|Kuprash, Dmitry V|Nedospasov, Sergei A
PMID: 18026951
Journal: Hum Pathol. 2011 Sep;42(9):1289-96.
Title: Frameshift mutations of poly(adenosine diphosphate-ribose) polymerase genes in gastric and colorectal cancers with microsatellite instability.
Author: Kim, Min Sung|An, Chang Hyeok|Kim, Sung Soo|Yoo, Nam Jin|Lee, Sug Hyung
PMID: 21333322
Journal: Cancer Res. 2012 Jun 1;72(11):2822-32.
Title: A novel tankyrase inhibitor decreases canonical Wnt signaling in colon carcinoma cells and reduces tumor growth in conditional APC mutant mice.
Author: Waaler, Jo|Machon, Ondrej|Tumova, Lucie|Dinh, Huyen|Korinek, Vladimir|Wilson, Steven Ray|Paulsen, Jan Erik|Pedersen, Nina Marie|Eide, Tor J|Machonova, Olga|Gradl, Dietmar|Voronkov, Andrey|von Kries, Jens Peter|Krauss, Stefan
PMID: 22440753
Journal: Int J Mol Epidemiol Genet. 2012;3(3):184-94. Epub 2012 Aug 31.
Title: Genetic and lifestyle influence on telomere length and subsequent risk of colon cancer in a case control study.
Author: Pellatt, Andrew J|Wolff, Roger K|Lundgreen, Abbie|Cawthon, Richard|Slattery, Martha L
PMID: 23050049
Journal: J Med Chem. 2013 Dec 27;56(24):10003-15.
Title: Development of novel dual binders as potent, selective, and orally bioavailable tankyrase inhibitors.
Author: Hua, Zihao|Bregman, Howard|Buchanan, John L|Chakka, Nagasree|Guzman-Perez, Angel|Gunaydin, Hakan|Huang, Xin|Gu, Yan|Berry, Virginia|Liu, Jingzhou|Teffera, Yohannes|Huang, Liyue|Egge, Bryan|Emkey, Renee|Mullady, Erin L|Schneider, Steve|Andrews, Paul S|Acqu
PMID: 24294969
Journal: ACS Med Chem Lett. 2013 Oct 21;4(12):1218-23.
Title: Structure-based design of 2-aminopyridine oxazolidinones as potent and selective tankyrase inhibitors.
Author: Huang, Hongbing|Guzman-Perez, Angel|Acquaviva, Lisa|Berry, Virginia|Bregman, Howard|Dovey, Jennifer|Gunaydin, Hakan|Huang, Xin|Huang, Liyue|Saffran, Doug|Serafino, Randy|Schneider, Steve|Wilson, Cindy|DiMauro, Erin F
PMID: 24900633
Journal: Mol Cancer Res. 2015 Nov;13(11):1487-501.
Title: Structure, Dynamics, and Functionality of Tankyrase Inhibitor-Induced Degradasomes.
Author: Thorvaldsen, Tor Espen|Pedersen, Nina Marie|Wenzel, Eva M|Schultz, Sebastian W|Brech, Andreas|Liestol, Knut|Waaler, Jo|Krauss, Stefan|Stenmark, Harald
PMID: 26124443
Journal: J Biol Chem. 2016 Jun 10;291(24):12747-60.
Title: The Poly(ADP-ribose) Polymerase Enzyme Tankyrase Antagonizes Activity of the beta-Catenin Destruction Complex through ADP-ribosylation of Axin and APC2.
Author: Croy, Heather E|Fuller, Caitlyn N|Giannotti, Jemma|Robinson, Paige|Foley, Andrew V A|Yamulla, Robert J|Cosgriff, Sean|Greaves, Bradford D|von Kleeck, Ryan A|An, Hyun Hyung|Powers, Catherine M|Tran, Julie K|Tocker, Aaron M|Jacob, Kimberly D|Davis, Beckley
PMID: 27068743
Journal: PLoS One. 2016 Aug 2;11(8):e0160507.
Title: Formation of Tankyrase Inhibitor-Induced Degradasomes Requires Proteasome Activity.
Author: Pedersen, Nina Marie|Thorvaldsen, Tor Espen|Schultz, Sebastian Wolfgang|Wenzel, Eva Maria|Stenmark, Harald
PMID: 27482906
Journal: Mol Cancer Ther. 2016 Jul;15(7):1525-34.
Title: The Discovery and Characterization of K-756, a Novel Wnt/beta-Catenin Pathway Inhibitor Targeting Tankyrase.
Author: Okada-Iwasaki, Ryoko|Takahashi, Yuichi|Watanabe, Yasuo|Ishida, Hiroshi|Saito, Jun-Ichi|Nakai, Ryuichiro|Asai, Akira
PMID: 27196752
Journal: Development. 2016 May 15;143(10):1710-20.
Title: The ADP-ribose polymerase Tankyrase regulates adult intestinal stem cell proliferation during homeostasis in Drosophila.
Author: Wang, Zhenghan|Tian, Ai|Benchabane, Hassina|Tacchelly-Benites, Ofelia|Yang, Eungi|Nojima, Hisashi|Ahmed, Yashi
PMID: 27190037
Journal: PLoS One. 2016 Mar 1;11(3):e0150484.
Title: Tankyrase Inhibitors Stimulate the Ability of Tankyrases to Bind Axin and Drive Assembly of beta-Catenin Degradation-Competent Axin Puncta.
Author: Martino-Echarri, Estefania|Brocardo, Mariana G|Mills, Kate M|Henderson, Beric R
PMID: 26930278
Journal: PLoS One. 2017 Jan 20;12(1):e0170508.
Title: Differential Roles of AXIN1 and AXIN2 in Tankyrase Inhibitor-Induced Formation of Degradasomes and beta-Catenin Degradation.
Author: Thorvaldsen, Tor Espen|Pedersen, Nina Marie|Wenzel, Eva Maria|Stenmark, Harald
PMID: 28107521
Journal: BMB Rep. 2017 Aug;50(8):391-392.
Title: Survival of APC-mutant colorectal cancer cells requires interaction between tankyrase and a thiol peroxidase, peroxiredoxin II.
Author: Kang, Dong Hoon|Lee, Joanna H S|Kang, Sang Won
PMID: 28683851
Journal: Mol Cancer Res. 2018 Mar;16(3):543-553.
Title: TANKYRASE Inhibition Enhances the Antiproliferative Effect of PI3K and EGFR Inhibition, Mutually Affecting beta-CATENIN and AKT Signaling in Colorectal Cancer.
Author: Solberg, Nina T|Waaler, Jo|Lund, Kaja|Mygland, Line|Olsen, Petter A|Krauss, Stefan
PMID: 29222171
Journal: Cancer Chemother Pharmacol. 2018 Oct;82(4):635-647.
Title: Identification and preclinical characterization of a novel and potent poly (ADP-ribose) polymerase (PARP) inhibitor ZYTP1.
Author: Jain, Mukul R|Mohapatra, Jogeswar|Bandhyopadhyay, Debdutta|Chatterjee, Abhijit|Ghoshdastidar, Krishnarup|Patel, Dinesh|Patel, Ankit|Bhayani, Hitesh|Srivastava, Brijesh Kumar|Shedage, Sandeep A|Kadam, Pravin|Sundar, Rajesh|Patel, Harilal|Giri, Poonam|Patel
PMID: 30046848
Journal: J Biomol Struct Dyn. 2018 Sep 11:1-29.
Title: In silico insights on Tankyrase protein: a potential target for colorectal cancer.
Author: Lakshmanan, Loganathan|Muthusamy, Karthikeyan|Marshal, Jayaraj John|Kajamaideen, Afrinrilwana|Balthasar, Josephine Julia
PMID: 30204055