Literatures

Primary Site >> Colorectal Cancer

Gene >> TNFSF10

1.
Journal:	Scand J Gastroenterol Suppl. 1976;37:99-106.
Title:	Carcinoembryonic antigen (CEA). A prospective clinical trail in patients with gastrointestinal cancer.
Author:	Kjaer, M\|Fischerman, K
PMID:	1064149

2.
Journal:	Sem Hop. 1980 Nov 18-25;56(43-44):1779-86.
Title:	[Pelvic recurrence after abdomino-perineal resection for carcinoma of the rectum (author's transl)].
Author:	Bugat, R\|Nguyen, T D\|Naja, A\|Combes, P F
PMID:	6256878

3.
Journal:	Cancer Res. 1999 Dec 15;59(24):6153-8.
Title:	Tumor necrosis factor-related apoptosis-inducing ligand's antitumor activity in vivo is enhanced by the chemotherapeutic agent CPT-11.
Author:	Gliniak, B\|Le, T
PMID:	10626806

4.
Journal:	Prostate Cancer Prostatic Dis. 1999 Dec;2(5/6):227-233.
Title:	Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) for treatment of prostate cancer: first results and review of the literature.
Author:	Van Ophoven, A\|Ng, C P\|Patel, B\|Bonavida, B\|Belldegrun, A
PMID:	12497168

5.
Journal:	Mol Ther. 2000 Feb;1(2):130-44.
Title:	The TRAIL decoy receptor TRUNDD (DcR2, TRAIL-R4) is induced by adenovirus-p53 overexpression and can delay TRAIL-, p53-, and KILLER/DR5-dependent colon cancer apoptosis.
Author:	Meng, R D\|McDonald, E R 3rd\|Sheikh, M S\|Fornace, A J Jr\|El-Deiry, W S
PMID:	10933923

6.
Journal:	Biochem Biophys Res Commun. 2000 Sep 24;276(2):466-71.
Title:	Isolation and molecular characterization of the 5'-upstream region of the human TRAIL gene.
Author:	Wang, Q\|Ji, Y\|Wang, X\|Evers, B M
PMID:	11027498

7.
Journal:	J Gene Med. 2000 Sep-Oct;2(5):334-43.
Title:	NF-kappaB kinetics predetermine TNF-alpha sensitivity of colorectal cancer cells.
Author:	Zwacka, R M\|Stark, L\|Dunlop, M G
PMID:	11045427

8.
Journal:	Cancer Res. 2000 Nov 15;60(22):6259-65.
Title:	The caspase 9 inhibitor Z-LEHD-FMK protects human liver cells while permitting death of cancer cells exposed to tumor necrosis factor-related apoptosis-inducing ligand.
Author:	Ozoren, N\|Kim, K\|Burns, T F\|Dicker, D T\|Moscioni, A D\|El-Deiry, W S
PMID:	11103780

9.
Journal:	Ann N Y Acad Sci. 2000;915:162-70.
Title:	Expression and function of death receptors and their natural ligands in the intestine.
Author:	Strater, J\|Moller, P
PMID:	11193573

10.
Journal:	Exp Cell Res. 2001 Jan 15;262(2):154-69.
Title:	p53-independent upregulation of KILLER/DR5 TRAIL receptor expression by glucocorticoids and interferon-gamma.
Author:	Meng, R D\|El-Deiry, W S
PMID:	11139340

11.
Journal:	Cancer Res. 2001 Feb 15;61(4):1645-51.
Title:	Anticancer agents sensitize tumor cells to tumor necrosis factor-related apoptosis-inducing ligand-mediated caspase-8 activation and apoptosis.
Author:	Lacour, S\|Hammann, A\|Wotawa, A\|Corcos, L\|Solary, E\|Dimanche-Boitrel, M T
PMID:	11245478

12.
Journal:	J Immunol. 2001 Apr 15;166(8):4891-8.
Title:	Isotype-dependent inhibition of tumor growth in vivo by monoclonal antibodies to death receptor 4.
Author:	Chuntharapai, A\|Dodge, K\|Grimmer, K\|Schroeder, K\|Marsters, S A\|Koeppen, H\|Ashkenazi, A\|Kim, K J
PMID:	11290766

13.
Journal:	J Gastrointest Surg. 2001 Jan-Feb;5(1):56-65.
Title:	Sensitization of human colon cancer cells to TRAIL-mediated apoptosis.
Author:	Hernandez, A\|Wang, Q D\|Schwartz, S A\|Evers, B M
PMID:	11309649

14.
Journal:	Oncogene. 2001 Mar 22;20(12):1476-85.
Title:	Sodium nitroprusside enhances TRAIL-induced apoptosis via a mitochondria-dependent pathway in human colorectal carcinoma CX-1 cells.
Author:	Lee, Y J\|Lee, K H\|Kim, H R\|Jessup, J M\|Seol, D W\|Kim, T H\|Billiar, T R\|Song, Y K
PMID:	11313891

15.
Journal:	Oncogene. 2001 Jun 21;20(28):3726-34.
Title:	The monoclonal antibody 225 activates caspase-8 and induces apoptosis through a tumor necrosis factor receptor family-independent pathway.
Author:	Liu, B\|Fan, Z
PMID:	11439335

16.
Journal:	J Biol Chem. 2001 Oct 12;276(41):37879-86.
Title:	Identification of inhibitors of TRAIL-induced death (ITIDs) in the TRAIL-sensitive colon carcinoma cell line SW480 using a genetic approach.
Author:	Burns, T F\|El-Deiry, W S
PMID:	11486001

17.
Journal:	Surgery. 2001 Aug;130(2):265-72.
Title:	Butyrate sensitizes human colon cancer cells to TRAIL-mediated apoptosis.
Author:	Hernandez, A\|Thomas, R\|Smith, F\|Sandberg, J\|Kim, S\|Chung, D H\|Evers, B M
PMID:	11490359

18.
Journal:	FEBS Lett. 2001 Aug 17;503(2-3):151-7.
Title:	The anti-apoptotic protein BAG-3 is overexpressed in pancreatic cancer and induced by heat stress in pancreatic cancer cell lines.
Author:	Liao, Q\|Ozawa, F\|Friess, H\|Zimmermann, A\|Takayama, S\|Reed, J C\|Kleeff, J\|Buchler, M W
PMID:	11513873

19.
Journal:	Anticancer Res. 2001 Nov-Dec;21(6A):3733-8.
Title:	Interferon-gamma modulates TRAIL-mediated apoptosis in human colon carcinoma cells.
Author:	Langaas, V\|Shahzidi, S\|Johnsen, J I\|Smedsrod, B\|Sveinbjornsson, B
PMID:	11911240

20.
Journal:	Hum Gene Ther. 2002 Jan 20;13(2):275-86.
Title:	Electroporation-mediated tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)/Apo2L gene therapy for hepatocellular carcinoma.
Author:	Yamashita, Yo-Ichi\|Shimada, Mitsuo\|Tanaka, Shinji\|Okamamoto, Masahiro\|Miyazaki, Jun-Ichi\|Sugimachi, Keizo
PMID:	11812283

21.
Journal:	Oncogene. 2002 Jan 17;21(3):337-46.
Title:	Low glucose-enhanced TRAIL cytotoxicity is mediated through the ceramide-Akt-FLIP pathway.
Author:	Nam, Seon Young\|Amoscato, Andrew A\|Lee, Yong J
PMID:	11821946

22.
Journal:	Gastroenterology. 2002 Mar;122(3):659-66.
Title:	TRAIL and its receptors in the colonic epithelium: a putative role in the defense of viral infections.
Author:	Strater, Jorn\|Walczak, Henning\|Pukrop, Tanja\|Von Muller, Lutz\|Hasel, Cornelia\|Kornmann, Marko\|Mertens, Thomas\|Moller, Peter
PMID:	11874999

23.
Journal:	Nat Med. 2002 Mar;8(3):274-81.
Title:	Tumor-cell resistance to death receptor--induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax.
Author:	LeBlanc, Heidi\|Lawrence, David\|Varfolomeev, Eugene\|Totpal, Klara\|Morlan, John\|Schow, Peter\|Fong, Sharon\|Schwall, Ralph\|Sinicropi, Dominick\|Ashkenazi, Avi
PMID:	11875499

24.
Journal:	Cancer Res. 2002 Mar 15;62(6):1583-7.
Title:	Requirement of BAX for TRAIL/Apo2L-induced apoptosis of colorectal cancers: synergism with sulindac-mediated inhibition of Bcl-x(L).
Author:	Ravi, Rajani\|Bedi, Atul
PMID:	11912124

25.
Journal:	J Biol Chem. 2002 Jul 5;277(27):24631-7. Epub 2002 Apr 29.
Title:	Distinct intracellular signaling in tumor necrosis factor-related apoptosis-inducing ligand- and CD95 ligand-mediated apoptosis.
Author:	Velthuis, Jurjen H L\|Rouschop, Kasper M A\|De Bont, Hans J G M\|Mulder, Gerard J\|Nagelkerke, J Fred
PMID:	11980895

26.
Journal:	Zhonghua Zhong Liu Za Zhi. 2002 Mar;24(2):133-6.
Title:	[Action of apoptosis-induced ligand gene in relation to tumor necrosis factor on human colon cancer cell line HT29].
Author:	He, Chao\|Hu, Xiaotong\|Xu, Xiangming\|Fang, Bingliang
PMID:	12015033

27.
Journal:	Oncogene. 2002 May 16;21(22):3611-9.
Title:	Enhanced tumor killing by Apo2L/TRAIL and CPT-11 co-treatment is associated with p21 cleavage and differential regulation of Apo2L/TRAIL ligand and its receptors.
Author:	Xiang, Hong\|Fox, Judith A\|Totpal, Klara\|Aikawa, Mina\|Dupree, Kelly\|Sinicropi, Dominick\|Lowe, John\|Escandon, Enrique
PMID:	12032863

28.
Journal:	J Biol Chem. 2002 Sep 27;277(39):36602-10. Epub 2002 Jul 24.
Title:	Regulation of TRAIL expression by the phosphatidylinositol 3-kinase/Akt/GSK-3 pathway in human colon cancer cells.
Author:	Wang, Qingding\|Wang, Xiaofu\|Hernandez, Ambrosio\|Hellmich, Mark R\|Gatalica, Zoran\|Evers, B Mark
PMID:	12140294

29.
Journal:	Int J Oncol. 2002 Sep;21(3):643-8.
Title:	Supra-additive antitumor activity of 5FU with tumor necrosis factor-related apoptosis-inducing ligand on gastric and colon cancers in vitro.
Author:	Shimoyama, Shouji\|Mochizuki, Yoshino\|Kusada, Osamu\|Kaminishi, Michio
PMID:	12168112

30.
Journal:	Cancer Biol Ther. 2002 Jan-Feb;1(1):47-55.
Title:	The mutant p53-conformation modifying drug, CP-31398, can induce apoptosis of human cancer cells and can stabilize wild-type p53 protein.
Author:	Takimoto, Rishu\|Wang, Wenge\|Dicker, David T\|Rastinejad, Farzan\|Lyssikatos, Joseph\|el-Deiry, Wafik S
PMID:	12174820

31.
Journal:	Oncogene. 2002 Sep 5;21(39):6032-40.
Title:	Apo2L/TRAIL differentially modulates the apoptotic effects of sulindac and a COX-2 selective non-steroidal anti-inflammatory agent in Bax-deficient cells.
Author:	He, Qin\|Luo, Xiuquan\|Huang, Ying\|Sheikh, M Saeed
PMID:	12203115

32.
Journal:	Cancer Res. 2002 Sep 1;62(17):4903-8.
Title:	Cyclooxygenase-2 overexpression inhibits death receptor 5 expression and confers resistance to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human colon cancer cells.
Author:	Tang, Ximing\|Sun, Yun Jie\|Half, Elizabeth\|Kuo, M Tien\|Sinicrope, Frank
PMID:	12208739

33.
Journal:	Gene Ther. 2002 Sep;9(18):1262-70.
Title:	Mechanisms involved in development of resistance to adenovirus-mediated proapoptotic gene therapy in DLD1 human colon cancer cell line.
Author:	Zhang, L\|Gu, J\|Lin, T\|Huang, X\|Roth, J A\|Fang, B
PMID:	12215894

34.
Journal:	Cancer Res. 2002 Oct 15;62(20):5800-6.
Title:	Effects of tumor necrosis factor-related apoptosis-inducing ligand alone and in combination with chemotherapeutic agents on patients' colon tumors grown in SCID mice.
Author:	Naka, Takuji\|Sugamura, Kenji\|Hylander, Bonnie L\|Widmer, Michael B\|Rustum, Youcef M\|Repasky, Elizabeth A
PMID:	12384541

35.
Journal:	Neoplasia. 2002 Nov-Dec;4(6):551-7.
Title:	Defining characteristics of Types I and II apoptotic cells in response to TRAIL.
Author:	Ozoren, Nesrin\|El-Deiry, Wafik S
PMID:	12407450

36.
Journal:	Br Med Bull. 2002;64:227-54.
Title:	Therapeutics targeting signal transduction for patients with colorectal carcinoma.
Author:	de Bono, Johann S\|Rowinsky, Eric K
PMID:	12421735

37.
Journal:	Cell Cycle. 2002 Jan;1(1):82-9.
Title:	Enhanced sensitivity of G1 arrested human cancer cells suggests a novel therapeutic strategy using a combination of simvastatin and TRAIL.
Author:	Jin, Zhaoyu\|Dicker, David T\|El-Deiry, Wafik S
PMID:	12429913

38.
Journal:	Exp Cell Res. 2002 Dec 10;281(2):175-81.
Title:	Heat shock protects HCT116 and H460 cells from TRAIL-induced apoptosis.
Author:	Ozoren, Nesrin\|El-Deiry, Wafik
PMID:	12460647

39.
Journal:	Clin Cancer Res. 2002 Dec;8(12):3734-40.
Title:	Expression of TRAIL and TRAIL receptors in colon carcinoma: TRAIL-R1 is an independent prognostic parameter.
Author:	Strater, Jorn\|Hinz, Ulf\|Walczak, Henning\|Mechtersheimer, Gunhild\|Koretz, Karin\|Herfarth, Christian\|Moller, Peter\|Lehnert, Thomas
PMID:	12473583

40.
Journal:	Cell Death Differ. 2002 Dec;9(12):1321-33.
Title:	Death of HT29 adenocarcinoma cells induced by TNF family receptor activation is caspase-independent and displays features of both apoptosis and necrosis.
Author:	Wilson, C A\|Browning, J L
PMID:	12478469

41.
Journal:	Ai Zheng. 2002 Dec;21(12):1350-3.
Title:	[Phase III clinical study of a new anticancer drug atofluding].
Author:	Li, Qing\|Feng, Feng-yi\|Han, Jun\|Sui, Guang-jie\|Zhu, Yan-guang\|Zhang, Yang\|Zhang, Zhen-hua\|Li, Li\|Wang, Ping-hui\|Zhou, Mei-zhen\|Zhang, Ying-chao
PMID:	12520746

42.
Journal:	Cancer Res. 2003 Feb 1;63(3):621-6.
Title:	Rapid induction of apoptosis by combination of flavopiridol and tumor necrosis factor (TNF)-alpha or TNF-related apoptosis-inducing ligand in human cancer cell lines.
Author:	Kim, Dong-Myung\|Koo, Sun-Young\|Jeon, Kiwan\|Kim, Min Hyung\|Lee, Jinho\|Hong, Chang Yong\|Jeong, ShinWu
PMID:	12566305

43.
Journal:	Oncogene. 2003 Mar 27;22(12):1807-16.
Title:	Chemotherapy enhances TNF-related apoptosis-inducing ligand DISC assembly in HT29 human colon cancer cells.
Author:	Lacour, Sandrine\|Micheau, Olivier\|Hammann, Arlette\|Drouineaud, Veronique\|Tschopp, Jurg\|Solary, Eric\|Dimanche-Boitrel, Marie-Therese
PMID:	12660816

44.
Journal:	Immunobiology. 2003;207(2):115-27.
Title:	Interleukin-2 activated NK cells do not use the CD95L- and TRAIL-pathways in the rapid induction of apoptosis of rat colon carcinoma CC531s cells.
Author:	Velthuis, Jurjen H L\|de Bont, Hans J G M\|Medema, Jan-Paul\|Kuppen, Peter J K\|Mulder, Gerard J\|Nagelkerke, J Fred
PMID:	12675269

45.
Journal:	J Natl Cancer Inst. 2003 Apr 16;95(8):611-21.
Title:	Macrophages from cancer patients: analysis of TRAIL, TRAIL receptors, and colon tumor cell apoptosis.
Author:	Herbeuval, Jean-Philippe\|Lambert, Claude\|Sabido, Odile\|Cottier, Michele\|Fournel, Pierre\|Dy, Michel\|Genin, Christian
PMID:	12697854

46.
Journal:	World J Gastroenterol. 2003 May;9(5):965-9.
Title:	Tumor necrosis factor-related apoptosis-inducing ligand gene on human colorectal cancer cell line HT29.
Author:	Xu, Xiang-Ming\|He, Chao\|Hu, Xiao-Tong\|Fang, Bing-Liang
PMID:	12717839

47.
Journal:	Oncogene. 2003 May 1;22(17):2674-9.
Title:	Effect of Bax deficiency on death receptor 5 and mitochondrial pathways during endoplasmic reticulum calcium pool depletion-induced apoptosis.
Author:	He, Qin\|Montalbano, JoAnne\|Corcoran, Chad\|Jin, Weixin\|Huang, Ying\|Sheikh, M Saeed
PMID:	12730681

48.
Journal:	Int J Oncol. 2003 Jun;22(6):1241-5.
Title:	Cell to cell contact required for bystander effect of the TNF-related apoptosis-inducing ligand (TRAIL) gene.
Author:	Huang, Xuefeng\|Lin, Tongyu\|Gu, Jian\|Zhang, Lidong\|Roth, Jack A\|Liu, Jinsong\|Fang, Bingliang
PMID:	12738989

49.
Journal:	World J Gastroenterol. 2003 Jun;9(6):1241-5.
Title:	Synergistic antitumor effect of TRAIL and doxorubicin on colon cancer cell line SW480.
Author:	Xu, Li-Hong\|Deng, Chang-Sheng\|Zhu, You-Qing\|Liu, Shi-Quan\|Liu, Dong-Zhou
PMID:	12800232

50.
Journal:	J Pathol. 2003 Jul;200(3):327-35.
Title:	Expression of TRAIL (TNF-related apoptosis-inducing ligand) and its receptors in normal colonic mucosa, adenomas, and carcinomas.
Author:	Koornstra, Jan J\|Kleibeuker, Jan H\|van Geelen, Caroline M M\|Rijcken, Fleur E M\|Hollema, Harry\|de Vries, Elisabeth G E\|de Jong, Steven
PMID:	12845629

51.
Journal:	Br J Cancer. 2003 Jul 21;89(2):363-73.
Title:	Differential modulation of the TRAIL receptors and the CD95 receptor in colon carcinoma cell lines.
Author:	van Geelen, C M M\|de Vries, E G E\|Le, T K P\|van Weeghel, R P\|de Jong, S
PMID:	12865931

52.
Journal:	Oncogene. 2003 Aug 7;22(32):4953-63.
Title:	The proteasome inhibitor PS-341 overcomes TRAIL resistance in Bax and caspase 9-negative or Bcl-xL overexpressing cells.
Author:	Johnson, Thomas R\|Stone, Kimberley\|Nikrad, Malti\|Yeh, Tammie\|Zong, Wei-Xing\|Thompson, Craig B\|Nesterov, Alexandre\|Kraft, Andrew S
PMID:	12902978

53.
Journal:	Ai Zheng. 2003 Aug;22(8):816-20.
Title:	[Synergistic effect of tumor necrosis factor-related apoptosis inducing ligand (TRAIL) and doxorubicin on human colon cancer SW480 cells].
Author:	Xu, Li-Hong\|Deng, Chang-Sheng\|Zhu, You-Qing\|Liu, Shi-Quan
PMID:	12917026

54.
Journal:	Cell Death Differ. 2003 Sep;10(9):1078-89.
Title:	NF-kappaB-independent actions of sulfasalazine dissociate the CD95L- and Apo2L/TRAIL-dependent death signaling pathways in human malignant glioma cells.
Author:	Hermisson, M\|Weller, M
PMID:	12934082

55.
Journal:	Cancer Res. 2003 Aug 15;63(16):5118-25.
Title:	Rottlerin sensitizes colon carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis via uncoupling of the mitochondria independent of protein kinase C.
Author:	Tillman, David M\|Izeradjene, Kamel\|Szucs, Kinga Szekely\|Douglas, Leslie\|Houghton, Janet A
PMID:	12941843

56.
Journal:	Rom J Gastroenterol. 2003 Sep;12(3):207-14.
Title:	Colon polyps and cytokines: emerging immunological mechanisms.
Author:	Jacobson-Brown, Pearl\|Neuman, Manuela G
PMID:	14502322

57.
Journal:	J Nutr. 2003 Oct;133(10):3065-71.
Title:	Glutamine prevents cytokine-induced apoptosis in human colonic epithelial cells.
Author:	Evans, Mary E\|Jones, Dean P\|Ziegler, Thomas R
PMID:	14519785

58.
Journal:	Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):15095-100. Epub 2003 Nov 26.
Title:	Requirement of p53 targets in chemosensitization of colonic carcinoma to death ligand therapy.
Author:	Wang, Shulin\|El-Deiry, Wafik S
PMID:	14645705

59.
Journal:	Differentiation. 2003 Dec;71(9-10):542-8.
Title:	Quantum dot-based cell motility assay.
Author:	Pellegrino, Teresa\|Parak, Wolfgang J\|Boudreau, Rosanne\|Le Gros, Mark A\|Gerion, Daniele\|Alivisatos, A Paul\|Larabell, Carolyn A
PMID:	14686951

60.
Journal:	Clin Exp Metastasis. 2003;20(8):713-21.
Title:	Rat colon carcinoma cells that survived systemic immune surveillance are less sensitive to NK-cell mediated apoptosis.
Author:	Velthuis, Jurjen H L\|Stitzinger, Miranda\|Aalbers, Remco I J M\|de Bont, Hans J G M\|Mulder, Gerard J\|Kuppen, Peter J K\|Nagelkerke, J Fred
PMID:	14713105

61.
Journal:	Exp Cell Res. 2004 Feb 1;293(1):129-43.
Title:	Low extracellular pH augments TRAIL-induced apoptotic death through the mitochondria-mediated caspase signal transduction pathway.
Author:	Lee, Yong J\|Song, Jae J\|Kim, Jin H\|Kim, Hyeong-Reh Choi\|Song, Young K
PMID:	14729063

62.
Journal:	Cancer Biol Ther. 2004 Mar;3(3):296-301. Epub 2004 Mar 16.
Title:	Lack of p38 MAP kinase activation in TRAIL-resistant cells is not related to the resistance to TRAIL-mediated cell death.
Author:	Zhang, Lidong\|Zhu, Hongbo\|Davis, John J\|Jacob, Dietmar\|Wu, Shuhong\|Teraishi, Fuminori\|Gutierrez, Angelica\|Wang, Yibin\|Fang, Bingliang
PMID:	14749540

63.
Journal:	Gene Ther. 2004 Mar;11(6):534-43.
Title:	AAV-encoded expression of TRAIL in experimental human colorectal cancer leads to tumor regression.
Author:	Mohr, A\|Henderson, G\|Dudus, L\|Herr, I\|Kuerschner, T\|Debatin, K-M\|Weiher, H\|Fisher, K J\|Zwacka, R M
PMID:	14999225

64.
Journal:	Magn Reson Med. 2004 Mar;51(3):542-51.
Title:	Quantification of tumor tissue populations by multispectral analysis.
Author:	Carano, Richard A D\|Ross, Adrienne L\|Ross, Jed\|Williams, Simon P\|Koeppen, Hartmut\|Schwall, Ralph H\|Van Bruggen, Nicholas
PMID:	15004796

65.
Journal:	Vitam Horm. 2004;67:291-318.
Title:	Interferon-gamma and TRAIL in human breast tumor cells.
Author:	Ruiz de Almodovar, Carmen\|Lopez-Rivas, Abelardo\|Ruiz-Ruiz, Carmen
PMID:	15110183

66.
Journal:	Mol Ther. 2004 May;9(5):666-73.
Title:	Overcoming acquired resistance to TRAIL by chemotherapeutic agents and calpain inhibitor I through distinct mechanisms.
Author:	Zhu, Hongbo\|Zhang, Lidong\|Huang, Xuefeng\|Davis, John J\|Jacob, Dietmar A\|Teraishi, Fuminori\|Chiao, Paul\|Fang, Bingliang
PMID:	15120327

67.
Journal:	Carcinogenesis. 2004 Oct;25(10):1813-20.
Title:	Sodium butyrate sensitizes TRAIL-mediated apoptosis by induction of transcription from the DR5 gene promoter through Sp1 sites in colon cancer cells.
Author:	Kim, Young-Ho\|Park, Jong-Wook\|Lee, Jai-Youl\|Kwon, Taeg Kyu
PMID:	15142888

68.
Journal:	J Biol Chem. 2004 Aug 20;279(34):35829-39. Epub 2004 May 20.
Title:	Deficient tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor transport to the cell surface in human colon cancer cells selected for resistance to TRAIL-induced apoptosis.
Author:	Jin, Zhaoyu\|McDonald, E Robert 3rd\|Dicker, David T\|El-Deiry, Wafik S
PMID:	15155747

69.
Journal:	Clin Cancer Res. 2004 May 15;10(10):3535-41.
Title:	Suppressing orthotopic pancreatic tumor growth with a fiber-modified adenovector expressing the TRAIL gene from the human telomerase reverse transcriptase promoter.
Author:	Jacob, Dietmar\|Davis, John\|Zhu, Hongbo\|Zhang, Lidong\|Teraishi, Fuminori\|Wu, Shuhong\|Marini, Frank C 3rd\|Fang, Bingliang
PMID:	15161713

70.
Journal:	Pharmacol Res. 2004 Aug;50(2):201-7.
Title:	Echinomycin and a novel analogue induce apoptosis of HT-29 cells via the activation of MAP kinases pathway.
Author:	Park, Ju Youn\|Park, Su Jung\|Shim, Kwang Yong\|Lee, Kyu Jae\|Kim, Yun-Bong\|Kim, Yong Hae\|Kim, Soo Kie
PMID:	15177310

71.
Journal:	Cancer Res. 2004 Jun 15;64(12):4078-81.
Title:	Hypoxia inhibits tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by blocking Bax translocation.
Author:	Kim, Moonil\|Park, Sang-Youel\|Pai, Hyun-Sook\|Kim, Tae-Hyoung\|Billiar, Timothy R\|Seol, Dai-Wu
PMID:	15205314

72.
Journal:	J Biol Chem. 2004 Sep 17;279(38):40044-52. Epub 2004 Jun 28.
Title:	Death induction by recombinant native TRAIL and its prevention by a caspase 9 inhibitor in primary human esophageal epithelial cells.
Author:	Kim, Seok-Hyun\|Kim, Kunhong\|Kwagh, Jae G\|Dicker, David T\|Herlyn, Meenhard\|Rustgi, Anil K\|Chen, Youhai\|El-Deiry, Wafik S
PMID:	15226295

73.
Journal:	Drug Metab Dispos. 2004 Nov;32(11):1230-8. Epub 2004 Jul 28.
Title:	Tissue distribution, stability, and pharmacokinetics of Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand in human colon carcinoma COLO205 tumor-bearing nude mice.
Author:	Xiang, Hong\|Nguyen, Cindy B\|Kelley, Sean K\|Dybdal, Noel\|Escandon, Enrique
PMID:	15282212

74.
Journal:	Cancer Res. 2004 Sep 15;64(18):6666-72.
Title:	Inducible silencing of KILLER/DR5 in vivo promotes bioluminescent colon tumor xenograft growth and confers resistance to chemotherapeutic agent 5-fluorouracil.
Author:	Wang, Shulin\|El-Deiry, Wafik S
PMID:	15374982

75.
Journal:	Surg Endosc. 2004 Aug;18(8):1211-5.
Title:	Laparoscopic versus open total mesorectal excision with anal sphincter preservation for low rectal cancer.
Author:	Zhou, Z-G\|Hu, M\|Li, Y\|Lei, W-Z\|Yu, Y-Y\|Cheng, Z\|Li, L\|Shu, Y\|Wang, T-C
PMID:	15457380

76.
Journal:	Oncogene. 2004 Nov 25;23(55):8979-86.
Title:	Redistribution of CD95, DR4 and DR5 in rafts accounts for the synergistic toxicity of resveratrol and death receptor ligands in colon carcinoma cells.
Author:	Delmas, Dominique\|Rebe, Cedric\|Micheau, Olivier\|Athias, Anne\|Gambert, Philippe\|Grazide, Solene\|Laurent, Guy\|Latruffe, Norbert\|Solary, Eric
PMID:	15480430

77.
Journal:	Anticancer Res. 2004 Sep-Oct;24(5A):3075-9.
Title:	Gene therapy in colon cancer cells with a fiber-modified adenovector expressing the TRAIL gene driven by the hTERT promoter.
Author:	Jacob, Dietmar\|Bahra, Marcus\|Schumacher, Guido\|Neuhaus, Peter\|Fang, Bingliang
PMID:	15517918

78.
Journal:	FEBS Lett. 2004 Nov 5;577(1-2):309-13.
Title:	Ethanol acts as a potent agent sensitizing colon cancer cells to the TRAIL-induced apoptosis.
Author:	Vaculova, Alena\|Hofmanova, Jirina\|Soucek, Karel\|Andera, Ladislav\|Kozubik, Alois
PMID:	15527805

79.
Journal:	Z Gastroenterol. 2004 Dec;42(12):1363-70.
Title:	[Adenoviral vector expressing the TRAIL gene driven by the hTERT promoter].
Author:	Jacob, D\|Davis, J\|Schumacher, G\|Bahra, M\|Neuhaus, P\|Fang, B
PMID:	15592959

80.
Journal:	Cancer Res. 2004 Dec 15;64(24):9105-14.
Title:	Elimination of hepatic metastases of colon cancer cells via p53-independent cross-talk between irinotecan and Apo2 ligand/TRAIL.
Author:	Ravi, Rajani\|Jain, Ajay J\|Schulick, Richard D\|Pham, Vui\|Prouser, Traci S\|Allen, Heather\|Mayer, Elizabeth Garrett\|Yu, Hua\|Pardoll, Drew M\|Ashkenazi, Avi\|Bedi, Atul
PMID:	15604280

81.
Journal:	Clin Cancer Res. 2004 Dec 15;10(24):8284-92.
Title:	Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis is inhibited by Bcl-2 but restored by the small molecule Bcl-2 inhibitor, HA 14-1, in human colon cancer cells.
Author:	Sinicrope, Frank A\|Penington, Robert C\|Tang, Xi Ming
PMID:	15623604

82.
Journal:	Drug Resist Updat. 2004 Dec;7(6):345-58.
Title:	Lessons from TRAIL-resistance mechanisms in colorectal cancer cells: paving the road to patient-tailored therapy.
Author:	Van Geelen, Caroline M M\|de Vries, Elisabeth G E\|de Jong, Steven
PMID:	15790545

83.
Journal:
Title:	(99m)Tc-Labeled lexatumumab
Author:	Chopra, Arvind
PMID:	20641185

84.
Journal:
Title:	(99m)Tc-Labeled mapatumumab
Author:	Chopra, Arvind
PMID:	20641397

85.
Journal:
Title:	(111)In-Labeled mapatumumab
Author:	Chopra, Arvind
PMID:	20641403

86.
Journal:
Title:	(111)In-Labeled lexatumumab
Author:	Chopra, Arvind
PMID:	20641892

87.
Journal:	Biochem Pharmacol. 2005 Feb 1;69(3):463-71.
Title:	Impaired activation of caspases and prevention of mitochondrial dysfunction in the metastatic colon carcinoma CC531s-m2 cell line.
Author:	Velthuis, Jurjen H L\|Gavric, Zoran\|de Bont, Hans J G M\|Nagelkerke, J Fred
PMID:	15652237

88.
Journal:	Br J Cancer. 2005 Feb 28;92(4):736-42.
Title:	Increased sensitivity to TRAIL-induced apoptosis occurs during the adenoma to carcinoma transition of colorectal carcinogenesis.
Author:	Hague, A\|Hicks, D J\|Hasan, F\|Smartt, H\|Cohen, G M\|Paraskeva, C\|MacFarlane, M
PMID:	15685228

89.
Journal:	Oncogene. 2005 Mar 17;24(12):2050-8.
Title:	Casein kinase II (CK2) enhances death-inducing signaling complex (DISC) activity in TRAIL-induced apoptosis in human colon carcinoma cell lines.
Author:	Izeradjene, Kamel\|Douglas, Leslie\|Delaney, Addison\|Houghton, Janet A
PMID:	15688023

90.
Journal:	J Biol Chem. 2005 Jun 17;280(24):22856-67.
Title:	Transformation by oncogenic RAS sensitizes human colon cells to TRAIL-induced apoptosis by up-regulating death receptor 4 and death receptor 5 through a MEK-dependent pathway.
Author:	Drosopoulos, Konstantinos G\|Roberts, Michael L\|Cermak, Lukas\|Sasazuki, Takehiko\|Shirasawa, Senji\|Andera, Ladislav\|Pintzas, Alexander
PMID:	15757891

91.
Journal:	Mol Cancer Ther. 2005 Mar;4(3):443-9.
Title:	The proteasome inhibitor bortezomib sensitizes cells to killing by death receptor ligand TRAIL via BH3-only proteins Bik and Bim.
Author:	Nikrad, Malti\|Johnson, Thomas\|Puthalalath, Hamsa\|Coultas, Leigh\|Adams, Jerry\|Kraft, Andrew S
PMID:	15767553

92.
Journal:	Mol Ther. 2005 Apr;11(4):531-41.
Title:	Effective gene-virotherapy for complete eradication of tumor mediated by the combination of hTRAIL (TNFSF10) and plasminogen k5.
Author:	Liu, Xin-Yuan\|Qiu, Song-Bo\|Zou, Wei-Gou\|Pei, Zi-Fei\|Gu, Jin-Fa\|Luo, Chun-Xia\|Ruan, Hong-Mei\|Chen, Yu\|Qi, Yi-Peng\|Qian, Cheng
PMID:	15771956

93.
Journal:	Clin Cancer Res. 2005 Apr 15;11(8):3075-83.
Title:	Role of intracellular glutathione in cell sensitivity to the apoptosis induced by tumor necrosis factor {alpha}-related apoptosis-inducing ligand/anticancer drug combinations.
Author:	Meurette, Olivier\|Lefeuvre-Orfila, Luz\|Rebillard, Amelie\|Lagadic-Gossmann, Dominique\|Dimanche-Boitrel, Marie-Therese
PMID:	15837763

94.
Journal:	Br J Cancer. 2005 Apr 25;92(8):1430-41.
Title:	HGS-ETR1, a fully human TRAIL-receptor 1 monoclonal antibody, induces cell death in multiple tumour types in vitro and in vivo.
Author:	Pukac, L\|Kanakaraj, P\|Humphreys, R\|Alderson, R\|Bloom, M\|Sung, C\|Riccobene, T\|Johnson, R\|Fiscella, M\|Mahoney, A\|Carrell, J\|Boyd, E\|Yao, X T\|Zhang, L\|Zhong, L\|von Kerczek, A\|Shepard, L\|Vaughan, T\|Edwards, B\|Dobson, C\|Salcedo, T\|Albert, V
PMID:	15846298

95.
Journal:	Eur J Cancer. 2005 May;41(8):1195-202.
Title:	Expression of tumour necrosis factor-related apoptosis-inducing ligand death receptors in sporadic and hereditary colorectal tumours: potential targets for apoptosis induction.
Author:	Koornstra, Jan J\|Jalving, Mathilde\|Rijcken, Fleur E M\|Westra, Jantine\|Zwart, Nynke\|Hollema, Harry\|de Vries, Elisabeth G E\|Hofstra, Robert W M\|Plukker, John T M\|de Jong, Steven\|Kleibeuker, Jan H
PMID:	15911244

96.
Journal:	Expert Rev Mol Diagn. 2005 May;5(3):353-75.
Title:	Molecular markers that predict response to colon cancer therapy.
Author:	Ahmed, Farid E
PMID:	15934813

97.
Journal:	Cancer Biol Ther. 2005 Jul;4(7):709-15. Epub 2005 Jul 28.
Title:	AKT activation and response to interferon-beta in human cancer cells.
Author:	Lei, Hanqin\|Furlong, Patrick J\|Ra, Jin Hee\|Mullins, Daniel\|Cantor, Robert\|Fraker, Douglas L\|Spitz, Francis R
PMID:	15970687

98.
Journal:	Biochem Pharmacol. 2005 Aug 15;70(4):580-9.
Title:	17-Allylamino-17-demethoxygeldanamycin overcomes TRAIL resistance in colon cancer cell lines.
Author:	Vasilevskaya, Irina A\|O'Dwyer, Peter J
PMID:	15993848

99.
Journal:	Neoplasia. 2005 Jun;7(6):594-602.
Title:	Accelerated degradation of caspase-8 protein correlates with TRAIL resistance in a DLD1 human colon cancer cell line.
Author:	Zhang, Lidong\|Zhu, Hongbo\|Teraishi, Fuminori\|Davis, John J\|Guo, Wei\|Fan, Zhen\|Fang, Bingliang
PMID:	16036110

100.
Journal:	Cancer Biol Ther. 2005 Jul;4(7):781-6. Epub 2005 Jul 6.
Title:	Proteasome inhibitors-mediated TRAIL resensitization and Bik accumulation.
Author:	Zhu, Hongbo\|Guo, Wei\|Zhang, Lidong\|Wu, Shuhong\|Teraishi, Fuminori\|Davis, John J\|Dong, Fengqin\|Fang, Bingliang
PMID:	16082182

101.
Journal:	Cell Cycle. 2005 Sep;4(9):1201-15.
Title:	Molecular targets and anticancer potential of indole-3-carbinol and its derivatives.
Author:	Aggarwal, Bharat B\|Ichikawa, Haruyo
PMID:	16082211

102.
Journal:	Biochim Biophys Acta. 2005 Aug 15;1745(1):101-10. Epub 2005 Jan 11.
Title:	Bcl-xL/Bax ratio is altered by IFNgamma in TNFalpha- but not in TRAIL-induced apoptosis in colon cancer cell line.
Author:	Baillat, Gilbert\|Garrouste, Francoise\|Remacle-Bonnet, Maryse\|Marvaldi, Jacques\|Pommier, Gilbert
PMID:	16085058

103.
Journal:	Cancer Res. 2005 Aug 15;65(16):7436-45.
Title:	Reactive oxygen species regulate caspase activation in tumor necrosis factor-related apoptosis-inducing ligand-resistant human colon carcinoma cell lines.
Author:	Izeradjene, Kamel\|Douglas, Leslie\|Tillman, David M\|Delaney, Addison B\|Houghton, Janet A
PMID:	16103097

104.
Journal:	Surgery. 2005 Aug;138(2):391-7.
Title:	Targeted RNA interference of PI3K pathway components sensitizes colon cancer cells to TNF-related apoptosis-inducing ligand (TRAIL).
Author:	Rychahou, Piotr G\|Murillo, Carlos A\|Evers, B Mark
PMID:	16153452

105.
Journal:	Cancer Lett. 2005 Nov 8;229(1):43-8. Epub 2005 Jan 18.
Title:	TRAIL and docosahexaenoic acid cooperate to induce HT-29 colon cancer cell death.
Author:	Vaculova, Alena\|Hofmanova, Jirina\|Andera, Ladislav\|Kozubik, Alois
PMID:	16157217

106.
Journal:	Mol Cancer Ther. 2005 Sep;4(9):1320-7.
Title:	Resistance to TRAIL is associated with defects in ceramide signaling that can be overcome by exogenous C6-ceramide without requiring down-regulation of cellular FLICE inhibitory protein.
Author:	Voelkel-Johnson, Christina\|Hannun, Yusuf A\|El-Zawahry, Ahmed
PMID:	16170023

107.
Journal:	Cancer Biol Ther. 2005 Aug;4(8):885-92.
Title:	Bioluminescent imaging of TRAIL-induced apoptosis through detection of caspase activation following cleavage of DEVD-aminoluciferin.
Author:	Liu, Jue Judy\|Wang, Wenge\|Dicker, David T\|El-Deiry, Wafik S
PMID:	16177559

108.
Journal:	J Biol Chem. 2005 Dec 9;280(49):41047-56.
Title:	Pretreatment of acetylsalicylic acid promotes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by down-regulating BCL-2 gene expression.
Author:	Kim, Ki M\|Song, Jae J\|An, Jee Young\|Kwon, Yong Tae\|Lee, Yong J
PMID:	16199534

109.
Journal:	Mol Cancer Ther. 2005 Oct;4(10):1475-83.
Title:	Sulindac sulfide-induced apoptosis is enhanced by a small-molecule Bcl-2 inhibitor and by TRAIL in human colon cancer cells overexpressing Bcl-2.
Author:	Sinicrope, Frank A\|Penington, Robert C
PMID:	16227396

110.
Journal:	Cancer Biol Ther. 2005 Sep;4(9):937-42. Epub 2005 Sep 18.
Title:	Non-invasive fluorescence imaging of cell death in fresh human colon epithelia treated with 5-Fluorouracil, CPT-11 and/or TRAIL.
Author:	Finnberg, Niklas\|Kim, Seok-Hyun\|Furth, Emma E\|Liu, Jue Judy\|Russo, Pierre\|Piccoli, David A\|Grimberg, Adda\|El-Deiry, Wafik S
PMID:	16251801

111.
Journal:	Cancer Biol Ther. 2005 Oct;4(10):1068-74. Epub 2005 Oct 18.
Title:	Modulation of TRAIL-induced tumor cell apoptosis in a hypoxic environment.
Author:	Mayes, Patrick A\|Campbell, Latoya\|Ricci, M Stacey\|Plastaras, John P\|Dicker, David T\|El-Deiry, Wafik S
PMID:	16294025

112.
Journal:	Anticancer Res. 2005 Nov-Dec;25(6B):3809-16.
Title:	Osteoprotegerin is expressed in colon carcinoma cells.
Author:	Pettersen, Ingvild\|Bakkelund, Wenche\|Smedsrod, Bard\|Sveinbjornsson, Baldur
PMID:	16309167

113.
Journal:	Cancer Res. 2005 Dec 15;65(24):11447-58.
Title:	Cyclooxygenase-2 inhibition sensitizes human colon carcinoma cells to TRAIL-induced apoptosis through clustering of DR5 and concentrating death-inducing signaling complex components into ceramide-enriched caveolae.
Author:	Martin, Sophie\|Phillips, Darren C\|Szekely-Szucs, Kinga\|Elghazi, Lynda\|Desmots, Fabienne\|Houghton, Janet A
PMID:	16357153

114.
Journal:	Mol Cancer Ther. 2005 Dec;4(12):2026-36.
Title:	Chemotherapy and TRAIL-mediated colon cancer cell death: the roles of p53, TRAIL receptors, and c-FLIP.
Author:	Galligan, Leeona\|Longley, Daniel B\|McEwan, Miranda\|Wilson, Timothy R\|McLaughlin, Kirsty\|Johnston, Patrick G
PMID:	16373718

115.
Journal:	Ann N Y Acad Sci. 2005 Nov;1059:160-7.
Title:	The proteasome inhibitor bortezomib (Velcade) sensitizes some human tumor cells to Apo2L/TRAIL-mediated apoptosis.
Author:	Brooks, Alan D\|Ramirez, Teresa\|Toh, Uhi\|Onksen, Jennifer\|Elliott, Peter J\|Murphy, William J\|Sayers, Thomas J
PMID:	16382051

116.
Journal:	Ann N Y Acad Sci. 2005 Nov;1056:379-87.
Title:	TRAIL (TNF-related apoptosis-inducing ligand) induces necrosis-like cell death in tumor cells at acidic extracellular pH.
Author:	Meurette, Olivier\|Huc, Laurence\|Rebillard, Amelie\|Le Moigne, Gwenaelle\|Lagadic-Gossmann, Dominique\|Dimanche-Boitrel, Marie-Therese
PMID:	16387703

117.
Journal:	Guang Pu Xue Yu Guang Pu Fen Xi. 2005 Dec;25(12):2029-33.
Title:	[Study of a multivariate statistical 5-ALA-based discrimination method for fluorescence spectra of colonic tissue of SD rats].
Author:	Xia, Dai-Lin\|He, Ji-Shan\|Zhang, Yang-De\|Tang, Jiang-Tian\|Zhang, Bo\|Wang, Shao-Chuang\|Huang, Qiu-Lin
PMID:	16544499

118.
Journal:	Int J Cancer. 2006 Jan 15;118(2):326-34.
Title:	PKCdelta-mediated regulation of FLIP expression in human colon cancer cells.
Author:	Wang, Qingding\|Wang, Xiaofu\|Zhou, Yuning\|Evers, B Mark
PMID:	16052516

119.
Journal:	Cell Death Differ. 2006 Feb;13(2):189-201.
Title:	Agonists of an ecdysone-inducible mammalian expression system inhibit Fas Ligand- and TRAIL-induced apoptosis in the human colon carcinoma cell line RKO.
Author:	Oehme, I\|Bosser, S\|Zornig, M
PMID:	16082389

120.
Journal:	Oncogene. 2006 Feb 9;25(6):838-48.
Title:	c-FLIP inhibits chemotherapy-induced colorectal cancer cell death.
Author:	Longley, D B\|Wilson, T R\|McEwan, M\|Allen, W L\|McDermott, U\|Galligan, L\|Johnston, P G
PMID:	16247474

121.
Journal:	Int J Cancer. 2006 May 1;118(9):2237-46.
Title:	TRAIL-induced cell death cooperates with IFN-gamma activation in the graft-versus-tumor effect against colon tumors.
Author:	Tateishi, Keisuke\|Ohta, Miki\|Guleng, Bayasi\|Kanai, Fumihiko\|Tanaka, Yasuo\|Asaoka, Yoshinari\|Jazag, Amarsanaa\|Imamura, Jun\|Imamura, Takaaki\|Ijichi, Hideaki\|Ikenoue, Tsuneo\|Kawakami, Takayuki\|Fukushima, Yasushi\|Washida, Miwa\|Sata, Masataka\|Miyagishi, Makoto
PMID:	16331624

122.
Journal:	Cancer Detect Prev. 2006;30(1):94-8.
Title:	Immunomodulation with low dose levamisole in patients with colonic polyps.
Author:	Holcombe, Randall F\|McLaren, Christine E\|Milovanovic, Tatjana
PMID:	16458451

123.
Journal:	Zhejiang Da Xue Xue Bao Yi Xue Ban. 2006 Jan;35(1):45-9.
Title:	[Activity of the TNF-related apoptosis-inducing ligand gene expressed from the hTERT promoter on colon cancer cell line HT-29].
Author:	Chen, Bin\|He, Chao\|Lao, Wei-feng\|Huang, Xue-feng\|Fang, Bing-liang
PMID:	16470920

124.
Journal:	Ai Zheng. 2006 Apr;25(4):385-92.
Title:	[Security of dual cancer-specific targeting vector and its cytotoxic effect when harbored].
Author:	Wang, Juan\|Gu, Jin-Fa\|Yang, Shui-Yun\|Xiao, Tian\|Qi, Rong\|Sun, Lan-Ying\|Liu, Xin-Yuan
PMID:	16613667

125.
Journal:	Cancer Res. 2006 Apr 15;66(8):4291-8.
Title:	Complete elimination of colorectal tumor xenograft by combined manganese superoxide dismutase with tumor necrosis factor-related apoptosis-inducing ligand gene virotherapy.
Author:	Zhang, Yanhong\|Gu, Jinfa\|Zhao, Lili\|He, Lingfeng\|Qian, Wenbin\|Wang, Jinhui\|Wang, Yigang\|Qian, Qijun\|Qian, Cheng\|Wu, Jian\|Liu, Xin Yuan
PMID:	16618754

126.
Journal:	Oncogene. 2006 Sep 14;25(41):5640-7. Epub 2006 Apr 17.
Title:	Proline oxidase activates both intrinsic and extrinsic pathways for apoptosis: the role of ROS/superoxides, NFAT and MEK/ERK signaling.
Author:	Liu, Y\|Borchert, G L\|Surazynski, A\|Hu, C-A\|Phang, J M
PMID:	16619034

127.
Journal:	Cancer Res. 2006 May 15;66(10):5403-8.
Title:	KRAS(D13) Promotes apoptosis of human colorectal tumor cells by ReovirusT3D and oxaliplatin but not by tumor necrosis factor-related apoptosis-inducing ligand.
Author:	Smakman, Niels\|van den Wollenberg, Diana J M\|Elias, Sjoerd G\|Sasazuki, Takehiko\|Shirasawa, Senji\|Hoeben, Rob C\|Borel Rinkes, Inne H M\|Kranenburg, Onno
PMID:	16707468

128.
Journal:	Cancer Gene Ther. 2006 Nov;13(11):1011-22. Epub 2006 Jun 23.
Title:	The antitumor activity of TRAIL and IL-24 with replicating oncolytic adenovirus in colorectal cancer.
Author:	Zhao, L\|Dong, A\|Gu, J\|Liu, Z\|Zhang, Y\|Zhang, W\|Wang, Y\|He, L\|Qian, C\|Qian, Q\|Liu, X
PMID:	16799468

129.
Journal:	Proc Natl Acad Sci U S A. 2006 Jul 18;103(29):11003-8.
Title:	Small-molecule modulators of p53 family signaling and antitumor effects in p53-deficient human colon tumor xenografts.
Author:	Wang, Wenge\|Kim, Seok-Hyun\|El-Deiry, Wafik S
PMID:	16835297

130.
Journal:	Clin Cancer Res. 2006 Jul 15;12(14 Pt 1):4350-6.
Title:	TRAIL induces apoptosis in human colorectal adenoma cell lines and human colorectal adenomas.
Author:	Jalving, Mathilde\|de Jong, Steven\|Koornstra, Jan J\|Boersma-van Ek, Wytske\|Zwart, Nynke\|Wesseling, Jelle\|de Vries, Elisabeth G E\|Kleibeuker, Jan H
PMID:	16857810

131.
Journal:	Immunology. 2006 Aug;118(4):483-96.
Title:	Anti-idiotype antibody induced cellular immunity in mice transgenic for human carcinoembryonic antigen.
Author:	Saha, Asim\|Chatterjee, Sunil K\|Foon, Kenneth A\|Bhattacharya-Chatterjee, Malaya
PMID:	16895556

132.
Journal:	Pathol Oncol Res. 2006;12(3):133-42. Epub 2006 Sep 23.
Title:	Proteasome inhibitors sensitize colon carcinoma cells to TRAIL-induced apoptosis via enhanced release of Smac/DIABLO from the mitochondria.
Author:	Nagy, Katalin\|Szekely-Szuts, Kinga\|Izeradjene, Kamel\|Douglas, Leslie\|Tillman, Mike\|Barti-Juhasz, Helga\|Dominici, Massimo\|Spano, Carlotta\|Luca Cervo, Gian\|Conte, Pierfranco\|Houghton, Janet A\|Mihalik, Rudolf\|Kopper, Laszlo\|Petak, Istvan
PMID:	16998592

133.
Journal:	Cancer Biol Ther. 2006 Nov;5(11):1511-20. Epub 2006 Nov 19.
Title:	Photochemically mediated delivery of AdhCMV-TRAIL augments the TRAIL-induced apoptosis in colorectal cancer cell lines.
Author:	Engesaeter, Birgit O\|Bonsted, Anette\|Lillehammer, Trine\|Engebraaten, Olav\|Berg, Kristian\|Maelandsmo, Gunhild M
PMID:	17012835

134.
Journal:	FEBS Lett. 2006 Dec 11;580(28-29):6565-9.
Title:	Different modulation of TRAIL-induced apoptosis by inhibition of pro-survival pathways in TRAIL-sensitive and TRAIL-resistant colon cancer cells.
Author:	Vaculova, Alena\|Hofmanova, Jirina\|Soucek, Karel\|Kozubik, Alois
PMID:	17113582

135.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2006 Nov;9(6):519-22.
Title:	[Study on the effects of mitochondrial pathways on apoptosis in colon carcinoma cells induced by tumor necrosis factor related apoptosis inducing ligand].
Author:	Hao, Ji-hui\|Yu, Ming\|Li, Qiang\|Shi, Yu-rong\|Yang, Yi\|Hao, Xi-shan
PMID:	17143800

136.
Journal:	Cancer Res. 2006 Dec 1;66(23):11115-9.
Title:	Cellular FLICE-inhibitory protein down-regulation contributes to celecoxib-induced apoptosis in human lung cancer cells.
Author:	Liu, Xiangguo\|Yue, Ping\|Schonthal, Axel H\|Khuri, Fadlo R\|Sun, Shi-Yong
PMID:	17145853

137.
Journal:	Mol Cancer Ther. 2006 Dec;5(12):2991-3000. Epub 2006 Dec 5.
Title:	Novel in vivo imaging shows up-regulation of death receptors by paclitaxel and correlates with enhanced antitumor effects of receptor agonist antibodies.
Author:	Gong, Jing\|Yang, David\|Kohanim, Saady\|Humphreys, Robin\|Broemeling, Lyle\|Kurzrock, Razelle
PMID:	17148761

138.
Journal:	Guang Pu Xue Yu Guang Pu Fen Xi. 2006 Nov;26(11):2076-9.
Title:	[Study of the methods of wavelet feature extraction and neural network classification of fluorescence spectra to improve the diagnostic rate of colonic earlier stage cancer].
Author:	Xia, Dai-lin\|Meng, Hong-xia\|Zhang, Yang-de\|He, Ji-shan
PMID:	17260761

139.
Journal:	Cancer Lett. 2007 Jan 8;245(1-2):134-43.
Title:	Soluble TRAIL gene and actinomycin D synergistically suppressed multiple metastasis of TRAIL-resistant colon cancer in the liver.
Author:	Ishii, Michiaki\|Iwai, Masaki\|Harada, Yoshinori\|Kishida, Tsunao\|Asada, Hidetsugu\|Shin-Ya, Masaharu\|Itoh, Yoshito\|Imanishi, Jiro\|Okanoue, Takeshi\|Mazda, Osam
PMID:	16478647

140.
Journal:	Cell Death Differ. 2007 Jan;14(1):137-45. Epub 2006 Apr 28.
Title:	Insulin-like growth factor binding protein 3 (IGFBP-3) potentiates TRAIL-induced apoptosis of human colorectal carcinoma cells through inhibition of NF-kappaB.
Author:	Williams, A C\|Smartt, H\|H-Zadeh, A M\|Macfarlane, M\|Paraskeva, C\|Collard, T J
PMID:	16645643

141.
Journal:	Cancer Res. 2007 Jan 1;67(1):218-26.
Title:	TRAIL induces receptor-interacting protein 1-dependent and caspase-dependent necrosis-like cell death under acidic extracellular conditions.
Author:	Meurette, Olivier\|Rebillard, Amelie\|Huc, Laurence\|Le Moigne, Gwenaelle\|Merino, Delphine\|Micheau, Olivier\|Lagadic-Gossmann, Dominique\|Dimanche-Boitrel, Marie-Therese
PMID:	17210702

142.
Journal:	J Cell Biochem. 2007 Jun 1;101(3):619-30.
Title:	Effect of hyperthermia on TRAIL-induced apoptotic death in human colon cancer cells: development of a novel strategy for regional therapy.
Author:	Yoo, Jinsang\|Lee, Yong J
PMID:	17212362

143.
Journal:	Cancer Res. 2007 Jan 15;67(2):674-83.
Title:	Nur77 agonists induce proapoptotic genes and responses in colon cancer cells through nuclear receptor-dependent and nuclear receptor-independent pathways.
Author:	Cho, Sung Dae\|Yoon, Kyungsil\|Chintharlapalli, Sudhakar\|Abdelrahim, Maen\|Lei, Ping\|Hamilton, Stanley\|Khan, Shaheen\|Ramaiah, Shashi K\|Safe, Stephen
PMID:	17234778

144.
Journal:	Cancer Sci. 2007 Mar;98(3):299-307.
Title:	Down-regulation of sialidase NEU4 may contribute to invasive properties of human colon cancers.
Author:	Yamanami, Hideaki\|Shiozaki, Kazuhiro\|Wada, Tadashi\|Yamaguchi, Kazunori\|Uemura, Takuji\|Kakugawa, Yoichiro\|Hujiya, Tsuneaki\|Miyagi, Taeko
PMID:	17270019

145.
Journal:	Int J Oncol. 2007 Mar;30(3):679-87.
Title:	Fenretinide up-regulates DR5/TRAIL-R2 expression via the induction of the transcription factor CHOP and combined treatment with fenretinide and TRAIL induces synergistic apoptosis in colon cancer cell lines.
Author:	Kouhara, Junji\|Yoshida, Tatsushi\|Nakata, Susumu\|Horinaka, Mano\|Wakada, Miki\|Ueda, Yuji\|Yamagishi, Hisakazu\|Sakai, Toshiyuki
PMID:	17273769

146.
Journal:	Drugs. 2007;67(3):333-50.
Title:	Monoclonal antibodies in the treatment of non-Hodgkin's lymphoma.
Author:	Fanale, Michelle A\|Younes, Anas
PMID:	17335294

147.
Journal:	Apoptosis. 2007 Jul;12(7):1299-315.
Title:	Bid is cleaved upstream of caspase-8 activation during TRAIL-mediated apoptosis in human osteosarcoma cells.
Author:	Garnett, Theodore O\|Filippova, Maria\|Duerksen-Hughes, Penelope Jayne
PMID:	17431792

148.
Journal:	Carcinogenesis. 2007 Jul;28(7):1575-81.
Title:	Chemopreventive effects of lupulone, a hop {beta}-acid, on human colon cancer-derived metastatic SW620 cells and in a rat model of colon carcinogenesis.
Author:	Lamy, Virginie\|Roussi, Stamatiki\|Chaabi, Mehdi\|Gosse, Francine\|Schall, Nicolas\|Lobstein, Annelise\|Raul, Francis
PMID:	17434926

149.
Journal:	Apoptosis. 2007 Aug;12(8):1465-78.
Title:	Expression of anti-apoptotic factors modulates Apo2L/TRAIL resistance in colon carcinoma cells.
Author:	Lippa, Mara S\|Strockbine, Laura D\|Le, Tiep T\|Branstetter, Daniel G\|Strathdee, Craig A\|Holland, Pamela M
PMID:	17440816

150.
Journal:	Mol Cancer Ther. 2007 May;6(5):1562-71.
Title:	5-Aminoimidazole-4-carboxamide riboside sensitizes TRAIL- and TNF{alpha}-induced cytotoxicity in colon cancer cells through AMP-activated protein kinase signaling.
Author:	Su, Rong-Ying\|Chao, Yee\|Chen, Tsai-Yu\|Huang, Duen-Yi\|Lin, Wan-Wan
PMID:	17513605

151.
Journal:	Br J Cancer. 2007 Jul 2;97(1):73-84. Epub 2007 Jun 5.
Title:	Newly established tumourigenic primary human colon cancer cell lines are sensitive to TRAIL-induced apoptosis in vitro and in vivo.
Author:	Oikonomou, E\|Kothonidis, K\|Taoufik, E\|Probert, E\|Zografos, G\|Nasioulas, G\|Andera, L\|Pintzas, A
PMID:	17551494

152.
Journal:	Histopathology. 2007 Aug;51(2):150-6. Epub 2007 Jun 8.
Title:	c-FLIP expression in colorectal carcinomas: association with Fas/FasL expression and prognostic implications.
Author:	Korkolopoulou, P\|Saetta, A A\|Levidou, G\|Gigelou, F\|Lazaris, A\|Thymara, I\|Scliri, M\|Bousboukea, K\|Michalopoulos, N V\|Apostolikas, N\|Konstantinidou, A\|Tzivras, M\|Patsouris, E
PMID:	17559541

153.
Journal:	Mol Cancer Res. 2007 Jun;5(6):615-25.
Title:	Halocynthiaxanthin and peridinin sensitize colon cancer cell lines to tumor necrosis factor-related apoptosis-inducing ligand.
Author:	Yoshida, Tatsushi\|Maoka, Takashi\|Das, Swadesh K\|Kanazawa, Kazuki\|Horinaka, Mano\|Wakada, Miki\|Satomi, Yoshiko\|Nishino, Hoyoku\|Sakai, Toshiyuki
PMID:	17579120

154.
Journal:	J Surg Res. 2007 Sep;142(1):184-94. Epub 2007 Jul 2.
Title:	Modification of gene products involved in resistance to apoptosis in metastatic colon cancer cells: roles of Fas, Apaf-1, NFkappaB, IAPs, Smac/DIABLO, and AIF.
Author:	Huerta, Sergio\|Heinzerling, John H\|Anguiano-Hernandez, Yu-Mei\|Huerta-Yepez, Sara\|Lin, Jeffrey\|Chen, David\|Bonavida, Benjamin\|Livingston, Edward H
PMID:	17603079

155.
Journal:	Cancer Cell. 2007 Jul;12(1):4-6.
Title:	Clearing the TRAIL for Cancer Therapy.
Author:	Hall, Mark A\|Cleveland, John L
PMID:	17613431

156.
Journal:	Cancer Res. 2007 Jul 15;67(14):6987-94.
Title:	Histone deacetylase inhibitors enhance lexatumumab-induced apoptosis via a p21Cip1-dependent decrease in survivin levels.
Author:	Nawrocki, Steffan T\|Carew, Jennifer S\|Douglas, Leslie\|Cleveland, John L\|Humphreys, Robin\|Houghton, Janet A
PMID:	17638911

157.
Journal:	Cancer Sci. 2007 Sep;98(9):1417-23.
Title:	Lipoxygenase inhibitors induce death receptor 5/TRAIL-R2 expression and sensitize malignant tumor cells to TRAIL-induced apoptosis.
Author:	Yoshida, Tatsushi\|Shiraishi, Takumi\|Horinaka, Mano\|Nakata, Susumu\|Yasuda, Takashi\|Goda, Ahmed E\|Wakada, Miki\|Mizutani, Yoichi\|Miki, Tsuneharu\|Nishikawa, Akiyoshi\|Sakai, Toshiyuki
PMID:	17645780

158.
Journal:	Clin Lung Cancer. 2007 Jul;8(7):413-9.
Title:	The potential of death receptor 4- and 5-directed therapies in the treatment of lung cancer.
Author:	Camidge, D Ross
PMID:	17681093

159.
Journal:	Cell Oncol. 2007;29(5):409-19.
Title:	Independent induction of caspase-8 and cFLIP expression during colorectal carcinogenesis in sporadic and HNPCC adenomas and carcinomas.
Author:	Heijink, D M\|Kleibeuker, J H\|Jalving, M\|Boersma-van Ek, W\|Koornstra, J J\|Wesseling, J\|de Jong, S
PMID:	17726263

160.
Journal:	Clin Cancer Res. 2007 Sep 1;13(17):5070-5.
Title:	Overexpression of FLIPL is an independent marker of poor prognosis in colorectal cancer patients.
Author:	Ullenhag, Gustave J\|Mukherjee, Abhik\|Watson, Nicholas F S\|Al-Attar, Ahmad H\|Scholefield, John H\|Durrant, Lindy G
PMID:	17785559

161.
Journal:	Mol Cancer Ther. 2007 Sep;6(9):2591-9.
Title:	Quercetin enhances TRAIL-mediated apoptosis in colon cancer cells by inducing the accumulation of death receptors in lipid rafts.
Author:	Psahoulia, Faiy H\|Drosopoulos, Konstantinos G\|Doubravska, Lenka\|Andera, Ladislav\|Pintzas, Alexander
PMID:	17876056

162.
Journal:	Cancer Biol Ther. 2007 Sep;6(9):1490-5. Epub 2007 Aug 17.
Title:	Chemotherapy-resistant side-population of colon cancer cells has a higher sensitivity to TRAIL than the non-SP, a higher expression of c-Myc and TRAIL-receptor DR4.
Author:	Sussman, Robyn T\|Ricci, M Stacey\|Hart, Lori S\|Sun, Shi Yong\|El-Deiry, Wafik S
PMID:	17881904

163.
Journal:	Int J Oncol. 2007 Dec;31(6):1391-402.
Title:	Differential response of p53 and p21 on HDAC inhibitor-mediated apoptosis in HCT116 colon cancer cells in vitro and in vivo.
Author:	Zopf, Steffen\|Neureiter, Daniel\|Bouralexis, Steve\|Abt, Tobias\|Glaser, Keith B\|Okamoto, Kinya\|Ganslmayer, Marion\|Hahn, Eckhart G\|Herold, Christoph\|Ocker, Matthias
PMID:	17982666

164.
Journal:	J Invest Surg. 2007 Nov-Dec;20(6):339-48.
Title:	Synergistic effects in apoptosis induction by taurolidine and TRAIL in HCT-15 colon carcinoma cells.
Author:	Chromik, A M\|Daigeler, A\|Hilgert, C\|Bulut, D\|Geisler, A\|Liu, V\|Otte, J M\|Uhl, W\|Mittelkotter, U
PMID:	18097875

165.
Journal:	Verh Dtsch Ges Pathol. 2007;91:294-301.
Title:	[The anti-diabetic drug troglitazone sensitizes colon cancer cells to TRAIL-induced apoptosis by down-regulating FLIP].
Author:	Roth, W\|Grund, K\|Wiestler, O D\|Schirmacher, P
PMID:	18314627

166.
Journal:	J Cell Biochem. 2008 Jan 1;103(1):98-109.
Title:	Effect of hyperthermia and chemotherapeutic agents on TRAIL-induced cell death in human colon cancer cells.
Author:	Yoo, Jinsang\|Lee, Yong J
PMID:	17520700

167.
Journal:	Oncogene. 2008 Jan 31;27(6):763-74. Epub 2007 Jul 23.
Title:	MnSOD protects colorectal cancer cells from TRAIL-induced apoptosis by inhibition of Smac/DIABLO release.
Author:	Mohr, A\|Buneker, C\|Gough, R P\|Zwacka, R M
PMID:	17653087

168.
Journal:	Apoptosis. 2008 Jan;13(1):63-75.
Title:	Apoptosis-associated antigens recognized by autoantibodies in patients with the autoimmune liver disease primary biliary cirrhosis.
Author:	Berg, Christoph Peter\|Stein, Gerburg Maria\|Keppeler, Hildegard\|Gregor, Michael\|Wesselborg, Sebastian\|Lauber, Kirsten
PMID:	18060504

169.
Journal:	Oncol Rep. 2008 Feb;19(2):567-73.
Title:	Response of normal and colon cancer epithelial cells to TNF-family apoptotic inducers.
Author:	Hofmanova, Jirina\|Vaculova, Alena\|Hyzd'alova, Martina\|Kozubik, Alois
PMID:	18202809

170.
Journal:	Carcinogenesis. 2008 Apr;29(4):849-57.
Title:	BAG-1 is up-regulated in colorectal tumour progression and promotes colorectal tumour cell survival through increased NF-kappaB activity.
Author:	Clemo, Nadine K\|Collard, Tracey J\|Southern, Samantha L\|Edwards, Kieron D\|Moorghen, Moganaden\|Packham, Graham\|Hague, Angela\|Paraskeva, Christos\|Williams, Ann C
PMID:	18204076

171.
Journal:	Cancer Res. 2008 Feb 1;68(3):909-17.
Title:	DR5 receptor mediates anoikis in human colorectal carcinoma cell lines.
Author:	Laguinge, Luciana M\|Samara, Raed N\|Wang, Wenge\|El-Deiry, Wafik S\|Corner, Georgia\|Augenlicht, Leonard\|Mishra, Lopa\|Jessup, J Milburn
PMID:	18245494

172.
Journal:	J Cell Biochem. 2008 Jul 1;104(4):1172-80.
Title:	Effect of UV irradiation on colorectal cancer cells with acquired TRAIL resistance.
Author:	Kim, Seong C\|Park, Sung-Soo\|Lee, Yong J
PMID:	18247342

173.
Journal:	Oncogene. 2008 Jul 10;27(30):4161-71.
Title:	P53-mediated upregulation of DcR1 impairs oxaliplatin/TRAIL-induced synergistic anti-tumour potential in colon cancer cells.
Author:	Toscano, F\|Fajoui, Z El\|Gay, F\|Lalaoui, N\|Parmentier, B\|Chayvialle, J-A\|Scoazec, J-Y\|Micheau, O\|Abello, J\|Saurin, J-C
PMID:	18345033

174.
Journal:	Clin Cancer Res. 2008 Apr 1;14(7):2180-9.
Title:	Treatment of human colon cancer xenografts with TRA-8 anti-death receptor 5 antibody alone or in combination with CPT-11.
Author:	Oliver, Patsy G\|LoBuglio, Albert F\|Zinn, Kurt R\|Kim, Hyunki\|Nan, Li\|Zhou, Tong\|Wang, Wenquan\|Buchsbaum, Donald J
PMID:	18381960

175.
Journal:	Oncogene. 2008 Oct 9;27(46):6012-22.
Title:	A mitochondrial block and expression of XIAP lead to resistance to TRAIL-induced apoptosis during progression to metastasis of a colon carcinoma.
Author:	Ndozangue-Touriguine, O\|Sebbagh, M\|Merino, D\|Micheau, O\|Bertoglio, J\|Breard, J
PMID:	18560353

176.
Journal:	Biochim Biophys Acta. 2008 Oct;1783(10):1903-13.
Title:	Intracellular signaling dynamics during apoptosis execution in the presence or absence of X-linked-inhibitor-of-apoptosis-protein.
Author:	O'Connor, Carla L\|Anguissola, Sergio\|Huber, Heinrich J\|Dussmann, Heiko\|Prehn, Jochen H M\|Rehm, Markus
PMID:	18590777

177.
Journal:	World J Gastroenterol. 2008 Jun 28;14(24):3829-40.
Title:	Bcl-x(L) and Myeloid cell leukaemia-1 contribute to apoptosis resistance of colorectal cancer cells.
Author:	Schulze-Bergkamen, Henning\|Ehrenberg, Roland\|Hickmann, Lothar\|Vick, Binje\|Urbanik, Toni\|Schimanski, Christoph-C\|Berger, Martin-R\|Schad, Arno\|Weber, Achim\|Heeger, Steffen\|Galle, Peter-R\|Moehler, Markus
PMID:	18609706

178.
Journal:	Clin Cancer Res. 2008 Aug 1;14(15):4713-8.
Title:	OPG is regulated by beta-catenin and mediates resistance to TRAIL-induced apoptosis in colon cancer.
Author:	De Toni, Enrico N\|Thieme, Susanne E\|Herbst, Andreas\|Behrens, Andrea\|Stieber, Petra\|Jung, Andreas\|Blum, Helmut\|Goke, Burkhard\|Kolligs, Frank T
PMID:	18676739

179.
Journal:	Biochem Biophys Res Commun. 2008 Oct 10;375(1):129-33.
Title:	Kaempferol sensitizes colon cancer cells to TRAIL-induced apoptosis.
Author:	Yoshida, Tatsushi\|Konishi, Masako\|Horinaka, Mano\|Yasuda, Takashi\|Goda, Ahmed E\|Taniguchi, Hiroya\|Yano, Kimihiro\|Wakada, Miki\|Sakai, Toshiyuki
PMID:	18680719

180.
Journal:	Oncology. 2008;74(3-4):188-97.
Title:	Synergism of CPT-11 and Apo2L/TRAIL against two differentially sensitive human colon tumor xenografts.
Author:	Sugamura, Kenji\|Gibbs, John F\|Belicha-Villanueva, Alan\|Andrews, Christopher\|Repasky, Elizabeth A\|Hylander, Bonnie L
PMID:	18714167

181.
Journal:	Apoptosis. 2008 Oct;13(10):1232-42.
Title:	Lupulone, a hop bitter acid, activates different death pathways involving apoptotic TRAIL-receptors, in human colon tumor cells and in their derived metastatic cells.
Author:	Lamy, Virginie\|Roussi, Stamatiki\|Chaabi, Mehdi\|Gosse, Francine\|Lobstein, Annelise\|Raul, Francis
PMID:	18726190

182.
Journal:	Eur J Cancer. 2008 Oct;44(15):2312-8.
Title:	Prognostic significance of TRAIL-R1 and TRAIL-R3 expression in metastatic colorectal carcinomas.
Author:	Granci, Virginie\|Bibeau, Frederic\|Kramar, Andrew\|Boissiere-Michot, Florence\|Thezenas, Simon\|Thirion, Agnes\|Gongora, Celine\|Martineau, Pierre\|Del Rio, Maguy\|Ychou, Marc
PMID:	18755584

183.
Journal:	Zhonghua Zhong Liu Za Zhi. 2008 Apr;30(4):245-9.
Title:	[Overcoming acquired resistance to tumor necrosis factor-related apoptosis-inducing ligand by Bcl-XL small interfering RNA in human colon cancer].
Author:	Zhu, Hong-Bo\|Huang, Xue-Feng\|Hu, Jing-Zi\|Zhou, Wei\|Chen, Wei\|Chen, Lin-Lin\|He, Chao
PMID:	18788624

184.
Journal:	J Clin Invest. 2008 Nov;118(11):3751-61.
Title:	CD4+CD25+ Tregs control the TRAIL-dependent cytotoxicity of tumor-infiltrating DCs in rodent models of colon cancer.
Author:	Roux, Stephan\|Apetoh, Lionel\|Chalmin, Fanny\|Ladoire, Sylvain\|Mignot, Gregoire\|Puig, Pierre-Emmanuel\|Lauvau, Gregoire\|Zitvogel, Laurence\|Martin, Francois\|Chauffert, Bruno\|Yagita, Hideo\|Solary, Eric\|Ghiringhelli, Francois
PMID:	18830416

185.
Journal:	Mol Cancer Ther. 2008 Oct;7(10):3429-40.
Title:	15-deoxy-Delta12,14-prostaglandin J2 up-regulates death receptor 5 gene expression in HCT116 cells: involvement of reactive oxygen species and C/EBP homologous transcription factor gene transcription.
Author:	Su, Rong-Ying\|Chi, Kwan-Hwa\|Huang, Duen-Yi\|Tai, Ming-Hui\|Lin, Wan-Wan
PMID:	18852146

186.
Journal:	Cancer Res. 2008 Oct 15;68(20):8312-21.
Title:	Src and ADAM-17-mediated shedding of transforming growth factor-alpha is a mechanism of acute resistance to TRAIL.
Author:	Van Schaeybroeck, Sandra\|Kelly, Donal M\|Kyula, Joan\|Stokesberry, Susan\|Fennell, Dean A\|Johnston, Patrick G\|Longley, Daniel B
PMID:	18922903

187.
Journal:	Cancer Res. 2008 Nov 1;68(21):8918-27.
Title:	Baicalein overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance via two different cell-specific pathways in cancer cells but not in normal cells.
Author:	Taniguchi, Hiroya\|Yoshida, Tatsushi\|Horinaka, Mano\|Yasuda, Takashi\|Goda, Ahmed E\|Konishi, Masako\|Wakada, Miki\|Kataoka, Keisho\|Yoshikawa, Toshikazu\|Sakai, Toshiyuki
PMID:	18974136

188.
Journal:	Cancer Biol Ther. 2008 Dec;7(12):2034-8.
Title:	TNFSF10 (TRAIL), a p53 target gene that mediates p53-dependent cell death.
Author:	Kuribayashi, Kageaki\|Krigsfeld, Gabriel\|Wang, Wenge\|Xu, Jing\|Mayes, Patrick A\|Dicker, David T\|Wu, Gen Sheng\|El-Deiry, Wafik S
PMID:	19106633

189.
Journal:	Environ Health Prev Med. 2008 Sep;13(5):281-7.
Title:	Combination of isoliquiritigenin and tumor necrosis factor-related apoptosis-inducing ligand induces apoptosis in colon cancer HT29 cells.
Author:	Yoshida, Tatsushi\|Horinaka, Mano\|Takara, Mami\|Tsuchihashi, Mayuko\|Mukai, Nobuhiro\|Wakada, Miki\|Sakai, Toshiyuki
PMID:	19568915

190.
Journal:	Cancer Immunol Immunother. 2009 May;58(5):699-708.
Title:	Immunosensitization with a Bcl-2 small molecule inhibitor.
Author:	Begley, Jonathan\|Vo, Dan D\|Morris, Lilah F\|Bruhn, Kevin W\|Prins, Robert M\|Mok, Stephen\|Koya, Richard C\|Garban, Hermes J\|Comin-Anduix, Begonya\|Craft, Noah\|Ribas, Antoni
PMID:	18807035

191.
Journal:	Cancer Chemother Pharmacol. 2009 Jul;64(2):307-16.
Title:	Stable XIAP knockdown clones of HCT116 colon cancer cells are more sensitive to TRAIL, taxanes and irradiation in vitro.
Author:	Connolly, Kate\|Mitter, Richard\|Muir, Morwenna\|Jodrell, Duncan\|Guichard, Sylvie
PMID:	19034449

192.
Journal:	Oncogene. 2009 Feb 26;28(8):1132-41.
Title:	Ceramide synthase 6 modulates TRAIL sensitivity and nuclear translocation of active caspase-3 in colon cancer cells.
Author:	White-Gilbertson, S\|Mullen, T\|Senkal, C\|Lu, P\|Ogretmen, B\|Obeid, L\|Voelkel-Johnson, C
PMID:	19137010

193.
Journal:	Strahlenther Onkol. 2009 Jan;185(1):8-18.
Title:	Efficacy of a triple treatment with irradiation, agonistic TRAIL receptor antibodies and EGFR blockade.
Author:	Niyazi, Maximilian\|Marini, Patrizia\|Daniel, Peter T\|Humphreys, Robin\|Jendrossek, Verena\|Belka, Claus
PMID:	19224142

194.
Journal:	Drug Resist Updat. 2009 Jun;12(3):55-64.
Title:	Targeting apoptosis as an approach for gastrointestinal cancer therapy.
Author:	Qiao, Liang\|Wong, Benjamin C Y
PMID:	19278896

195.
Journal:	Br J Cancer. 2009 May 5;100(9):1415-24.
Title:	Differential activation of JNK1 isoforms by TRAIL receptors modulate apoptosis of colon cancer cell lines.
Author:	Mahalingam, D\|Keane, M\|Pirianov, G\|Mehmet, H\|Samali, A\|Szegezdi, E
PMID:	19352384

196.
Journal:	Gastroenterology. 2009 Jul;137(1):188-98, 198.e1-2.
Title:	Deficiency of GMDS leads to escape from NK cell-mediated tumor surveillance through modulation of TRAIL signaling.
Author:	Moriwaki, Kenta\|Noda, Katsuhisa\|Furukawa, Yoichi\|Ohshima, Kenji\|Uchiyama, Airi\|Nakagawa, Tsutomu\|Taniguchi, Naoyuki\|Daigo, Yataro\|Nakamura, Yusuke\|Hayashi, Norio\|Miyoshi, Eiji
PMID:	19361506

197.
Journal:	Oncol Rep. 2009 Jun;21(6):1455-60.
Title:	Efficacy of triple therapies including ionising radiation, agonistic TRAIL antibodies and cisplatin.
Author:	Niyazi, Maximilian\|Marini, Patrizia\|Daniel, Peter T\|Humphreys, Robin\|Jendrossek, Verena\|Belka, Claus
PMID:	19424623

198.
Journal:	Biochem Pharmacol. 2009 May 1;77(9):1487-96.
Title:	A rice bran polyphenol, cycloartenyl ferulate, elicits apoptosis in human colorectal adenocarcinoma SW480 and sensitizes metastatic SW620 cells to TRAIL-induced apoptosis.
Author:	Kong, Carrie K L\|Lam, W S\|Chiu, Lawrence C M\|Ooi, Vincent E C\|Sun, Samuel S M\|Wong, Yum-Shing
PMID:	19426686

199.
Journal:	Br J Pharmacol. 2009 Aug;157(7):1189-202.
Title:	Reactive oxygen species up-regulate p53 and Puma; a possible mechanism for apoptosis during combined treatment with TRAIL and wogonin.
Author:	Lee, Dae-Hee\|Rhee, Juong G\|Lee, Yong J
PMID:	19438509

200.
Journal:	J Immunol. 2009 Jun 1;182(11):7287-96.
Title:	Efficient killing of human colon cancer stem cells by gammadelta T lymphocytes.
Author:	Todaro, Matilde\|D'Asaro, Matilde\|Caccamo, Nadia\|Iovino, Flora\|Francipane, Maria Giovanna\|Meraviglia, Serena\|Orlando, Valentina\|La Mendola, Carmela\|Gulotta, Gaspare\|Salerno, Alfredo\|Dieli, Francesco\|Stassi, Giorgio
PMID:	19454726

201.
Journal:	Gastroenterology. 2009 Jul;137(1):36-9.
Title:	Fucose is on the TRAIL of colon cancer.
Author:	Haltiwanger, Robert S
PMID:	19482107

202.
Journal:	J Cell Mol Med. 2009 Nov-Dec;13(11-12):4409-14.
Title:	Stem cells are resistant to TRAIL receptor-mediated apoptosis.
Author:	Szegezdi, Eva\|O'Reilly, Aoife\|Davy, Yeung\|Vawda, Reaz\|Taylor, Deanna L\|Murphy, Mary\|Samali, Afshin\|Mehmet, Huseyin
PMID:	19604313

203.
Journal:	Int J Cancer. 2009 Nov 1;125(9):2127-35.
Title:	TRAIL receptor upregulation and the implication of KRAS/BRAF mutations in human colon cancer tumors.
Author:	Oikonomou, Eftychia\|Kosmidou, Vivian\|Katseli, Anastasia\|Kothonidis, Konstantinos\|Mourtzoukou, Despina\|Kontogeorgos, George\|Andera, Ladislav\|Zografos, Georgios\|Pintzas, Alexander
PMID:	19637313

204.
Journal:	Cancer Res. 2009 Aug 15;69(16):6581-9.
Title:	Zerumbone enhances TRAIL-induced apoptosis through the induction of death receptors in human colon cancer cells: Evidence for an essential role of reactive oxygen species.
Author:	Yodkeeree, Supachai\|Sung, Bokyung\|Limtrakul, Pornngarm\|Aggarwal, Bharat B
PMID:	19654295

205.
Journal:	Nat Rev Gastroenterol Hepatol. 2009 Sep;6(9):507-9.
Title:	Colorectal cancer: Irinotecan therapy-following a trail of breadcrumbs?
Author:	Goldberg, Richard M\|O'Neil, Bert H
PMID:	19713983

206.
Journal:	Oncol Rep. 2009 Oct;22(4):765-71.
Title:	Enhanced radiosensitivity of SW480 cells via TRAIL up-regulation mediated by Egr-1 promoter.
Author:	Hu, Y\|Ouyang, W\|Wu, F\|Cao, C H\|Wang, K\|Liao, Z K\|Zhong, Y H\|Zhou, F X\|Liu, S Q\|Xia, L\|Zhou, Y F\|Xie, C H
PMID:	19724854

207.
Journal:	J Immunol. 2009 Oct 1;183(7):4371-7.
Title:	Phosphorothioate-modified TLR9 ligands protect cancer cells against TRAIL-induced apoptosis.
Author:	Chiron, David\|Pellat-Deceunynck, Catherine\|Maillasson, Mike\|Bataille, Regis\|Jego, Gaetan
PMID:	19734228

208.
Journal:	Oncogene. 2009 Nov 12;28(45):3983-96.
Title:	Increased proteasome subunit protein expression and proteasome activity in colon cancer relate to an enhanced activation of nuclear factor E2-related factor 2 (Nrf2).
Author:	Arlt, A\|Bauer, I\|Schafmayer, C\|Tepel, J\|Muerkoster, S Sebens\|Brosch, M\|Roder, C\|Kalthoff, H\|Hampe, J\|Moyer, M P\|Folsch, U R\|Schafer, H
PMID:	19734940

209.
Journal:	J Clin Biochem Nutr. 2009 Sep;45(2):163-70.
Title:	Cyclooxygenase 2 modulates killing of cytotoxic T lymphocytes by colon cancer cells.
Author:	Wang, Quanxin\|Takei, Yoshiyuki\|Kobayashi, Osamu\|Osada, Taro\|Watanabe, Sumio
PMID:	19794924

210.
Journal:	Hepatogastroenterology. 2009 Nov-Dec;56(96):1606-11.
Title:	Clinical application of sentinel lymph node biopsy for staging, treatment and prognosis of colon and gastric cancer.
Author:	Dragan, Radovanovic\|Nebojsa, Mitrovic\|Dejan, Stevanovic\|Ivan, Pavlovic\|Dragos, Stojanovic\|Damir, Jasarovic\|Predrag, Stevanovic\|Vladan, Zivaljevic
PMID:	20214202

211.
Journal:	Rozhl Chir. 2009 Dec;88(12):725-9.
Title:	[Comparison of oncological outcomes between laparoscopic and open procedures in non-metastazing colonic carcinomas].
Author:	Martinek, L\|Dostalik, J\|Gunka, I\|Gunkova, P\|Vavra, P
PMID:	20662437

212.
Journal:	J Cell Mol Med. 2010 Sep;14(9):2292-304.
Title:	Growth inhibition of colorectal carcinoma by lentiviral TRAIL-transgenic human mesenchymal stem cells requires their substantial intratumoral presence.
Author:	Luetzkendorf, Jana\|Mueller, Lutz P\|Mueller, Thomas\|Caysa, Henrike\|Nerger, Katrin\|Schmoll, Hans-Joachim
PMID:	19508388

213.
Journal:	Cancer Lett. 2010 Jan 1;287(1):98-108.
Title:	Nutlin-3 enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through up-regulation of death receptor 5 (DR5) in human sarcoma HOS cells and human colon cancer HCT116 cells.
Author:	Hori, Takeshi\|Kondo, Takashi\|Kanamori, Masahiko\|Tabuchi, Yoshiaki\|Ogawa, Ryohei\|Zhao, Qing-Li\|Ahmed, Kanwal\|Yasuda, Taketoshi\|Seki, Shoji\|Suzuki, Kayo\|Kimura, Tomoatsu
PMID:	19577358

214.
Journal:	Cancer Invest. 2010 Jan;28(1):23-32.
Title:	Synergistic anti-cancer activity by the combination of TRAIL/APO-2L and celastrol.
Author:	Zhu, Hong\|Ding, Wan-Jing\|Wu, Rui\|Weng, Qin-Jie\|Lou, Jian-Shu\|Jin, Rong-Jia\|Lu, Wei\|Yang, Bo\|He, Qiao-Jun
PMID:	19916747

215.
Journal:	Biochem Biophys Res Commun. 2010 Jan 8;391(2):1274-9.
Title:	Hypoxia-induced decoy receptor 2 gene expression is regulated via a hypoxia-inducible factor 1alpha-mediated mechanism.
Author:	Pei, Guo-Ting\|Wu, Chi-Wei\|Lin, Wan-Wan
PMID:	20018172

216.
Journal:	Br J Cancer. 2010 Feb 2;102(3):506-12.
Title:	Phase II trial of mapatumumab, a fully human agonistic monoclonal antibody that targets and activates the tumour necrosis factor apoptosis-inducing ligand receptor-1 (TRAIL-R1), in patients with refractory colorectal cancer.
Author:	Trarbach, T\|Moehler, M\|Heinemann, V\|Kohne, C-H\|Przyborek, M\|Schulz, C\|Sneller, V\|Gallant, G\|Kanzler, S
PMID:	20068564

217.
Journal:	Cancer. 2010 Mar 1;116(5):1252-63.
Title:	Tumor suppressor XIAP-Associated factor 1 (XAF1) cooperates with tumor necrosis factor-related apoptosis-inducing ligand to suppress colon cancer growth and trigger tumor regression.
Author:	Tu, Shui Ping\|Sun, Yun Wei\|Cui, Jian Tao\|Zou, Bing\|Lin, Marie C M\|Gu, Qing\|Jiang, Shi Hu\|Kung, Hsiang Fu\|Korneluk, Robert G\|Wong, Benjamin C Y
PMID:	20082449

218.
Journal:	Br J Cancer. 2010 Feb 16;102(4):754-64.
Title:	Early growth response-1 is a regulator of DR5-induced apoptosis in colon cancer cells.
Author:	Mahalingam, D\|Natoni, A\|Keane, M\|Samali, A\|Szegezdi, E
PMID:	20087343

219.
Journal:	Cancer Res. 2010 Feb 1;70(3):1101-10.
Title:	Multivalent DR5 peptides activate the TRAIL death pathway and exert tumoricidal activity.
Author:	Pavet, Valeria\|Beyrath, Julien\|Pardin, Christophe\|Morizot, Alexandre\|Lechner, Marie-Charlotte\|Briand, Jean-Paul\|Wendland, Miriam\|Maison, Wolfgang\|Fournel, Sylvie\|Micheau, Olivier\|Guichard, Gilles\|Gronemeyer, Hinrich
PMID:	20103630

220.
Journal:	Cancer Lett. 2010 Jul 28;293(2):158-66.
Title:	Synergistic antitumor effect of TRAIL in combination with sunitinib in vitro and in vivo.
Author:	Ding, Wanjing\|Cai, Tianyu\|Zhu, Hong\|Wu, Rui\|Tu, Chongxing\|Yang, Liuqing\|Lu, Wei\|He, Qiaojun\|Yang, Bo
PMID:	20137855

221.
Journal:	Cancer Biol Ther. 2010 Apr 15;9(8):618-31. Epub 2010 Apr 20.
Title:	Conatumumab, a fully human agonist antibody to death receptor 5, induces apoptosis via caspase activation in multiple tumor types.
Author:	Kaplan-Lefko, Paula J\|Graves, Jonathan D\|Zoog, Stephen J\|Pan, Yang\|Wall, Jason\|Branstetter, Daniel G\|Moriguchi, Jodi\|Coxon, Angela\|Huard, Justin N\|Xu, Ren\|Peach, Matthew L\|Juan, Gloria\|Kaufman, Stephen\|Chen, Qing\|Bianchi, Allison\|Kordich, Jennifer J\|Ma, M
PMID:	20150762

222.
Journal:	FEBS J. 2010 Apr;277(7):1653-65.
Title:	Synthetic constrained peptide selectively binds and antagonizes death receptor 5.
Author:	Vrielink, Johanna\|Heins, Mariette S\|Setroikromo, Rita\|Szegezdi, Eva\|Mullally, Margaret M\|Samali, Afshin\|Quax, Wim J
PMID:	20156289

223.
Journal:	Clin Cancer Res. 2010 Mar 1;16(5):1587-96.
Title:	Development of immunohistochemistry assays to assess GALNT14 and FUT3/6 in clinical trials of dulanermin and drozitumab.
Author:	Stern, Howard M\|Padilla, Mary\|Wagner, Klaus\|Amler, Lukas\|Ashkenazi, Avi
PMID:	20179215

224.
Journal:	Gene Ther. 2010 Apr;17(4):550-9.
Title:	TRAIL gene-armed oncolytic poxvirus and oxaliplatin can work synergistically against colorectal cancer.
Author:	Ziauddin, M F\|Guo, Z S\|O'Malley, M E\|Austin, F\|Popovic, P J\|Kavanagh, M A\|Li, J\|Sathaiah, M\|Thirunavukarasu, P\|Fang, B\|Lee, Y J\|Bartlett, D L
PMID:	20182517

225.
Journal:	Gastroenterology. 2010 Jun;138(7):2357-67.
Title:	Oncogenic K-Ras turns death receptors into metastasis-promoting receptors in human and mouse colorectal cancer cells.
Author:	Hoogwater, Frederik J H\|Nijkamp, Maarten W\|Smakman, Niels\|Steller, Ernst J A\|Emmink, Benjamin L\|Westendorp, B Florien\|Raats, Danielle A E\|Sprick, Martin R\|Schaefer, Uta\|Van Houdt, Winan J\|De Bruijn, Menno T\|Schackmann, Ron C J\|Derksen, Patrick W B\|Medema,
PMID:	20188103

226.
Journal:	Mol Cancer Ther. 2010 Apr;9(4):833-43.
Title:	beta-Ionone enhances TRAIL-induced apoptosis in hepatocellular carcinoma cells through Sp1-dependent upregulation of DR5 and downregulation of NF-kappaB activity.
Author:	Kim, Mun-Ock\|Moon, Dong-Oh\|Kang, Chang-Hee\|Kwon, Taeg Kyu\|Choi, Yung Hyun\|Kim, Gi-Young
PMID:	20354117

227.
Journal:	Cancer Res. 2010 May 1;70(9):3718-29.
Title:	Adipose-derived mesenchymal stem cells as stable source of tumor necrosis factor-related apoptosis-inducing ligand delivery for cancer therapy.
Author:	Grisendi, Giulia\|Bussolari, Rita\|Cafarelli, Luigi\|Petak, Istvan\|Rasini, Valeria\|Veronesi, Elena\|De Santis, Giorgio\|Spano, Carlotta\|Tagliazzucchi, Mara\|Barti-Juhasz, Helga\|Scarabelli, Laura\|Bambi, Franco\|Frassoldati, Antonio\|Rossi, Giulio\|Casali, Christian
PMID:	20388793

228.
Journal:	J Biol Chem. 2010 Jun 18;285(25):19162-72.
Title:	Inhibition of NF-kappaB signaling by quinacrine is cytotoxic to human colon carcinoma cell lines and is synergistic in combination with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) or oxaliplatin.
Author:	Jani, Tanvi S\|DeVecchio, Jennifer\|Mazumdar, Tapati\|Agyeman, Akwasi\|Houghton, Janet A
PMID:	20424169

229.
Journal:	Int J Oncol. 2010 Jun;36(6):1485-90.
Title:	Identification of gene expression profiles correlated to tumor progression in a preclinical model of colon carcinogenesis.
Author:	Bousserouel, Souad\|Kauntz, Henriette\|Gosse, Francine\|Bouhadjar, Mourad\|Soler, Luc\|Marescaux, Jacques\|Raul, Francis
PMID:	20428773

230.
Journal:	J Cell Biochem. 2010 Aug 1;110(5):1073-81.
Title:	Effect of hyperthermia in combination with TRAIL on the JNK-Bim signal transduction pathway and growth of xenograft tumors.
Author:	Alcala, Marco A Jr\|Park, Kyungsoo\|Yoo, Jinsang\|Lee, Dae-Hee\|Park, Bae-Hang\|Lee, Byeong-Chel\|Bartlett, David L\|Lee, Yong J
PMID:	20544795

231.
Journal:	Clin Cancer Res. 2010 Jul 1;16(13):3442-51.
Title:	Prognostic significance of TRAIL signaling molecules in stage II and III colorectal cancer.
Author:	McLornan, Donal P\|Barrett, Helen L\|Cummins, Robert\|McDermott, Ultan\|McDowell, Cliona\|Conlon, Susie J\|Coyle, Victoria M\|Van Schaeybroeck, Sandra\|Wilson, Richard\|Kay, Elaine W\|Longley, Daniel B\|Johnston, Patrick G
PMID:	20570920

232.
Journal:	Eur J Cancer. 2010 Aug;46(12):2314-23.
Title:	Tumour-mediated TRAIL-Receptor expression indicates effective apoptotic depletion of infiltrating CD8+ immune cells in clinical colorectal cancer.
Author:	Grimm, Martin\|Kim, Mia\|Rosenwald, Andreas\|von Raden, Burkhard H A\|Tsaur, Igor\|Meier, Eva\|Heemann, Uwe\|Germer, Christoph-Thomas\|Gasser, Martin\|Waaga-Gasser, Ana Maria
PMID:	20580220

233.
Journal:	PLoS One. 2010 Jul 22;5(7):e11700.
Title:	Tumor associated macrophages protect colon cancer cells from TRAIL-induced apoptosis through IL-1beta-dependent stabilization of Snail in tumor cells.
Author:	Kaler, Pawan\|Galea, Vincent\|Augenlicht, Leonard\|Klampfer, Lidija
PMID:	20661477

234.
Journal:	Mol Cancer. 2010 Jul 30;9:203.
Title:	Prognostic significance of TRAIL death receptors in Middle Eastern colorectal carcinomas and their correlation to oncogenic KRAS alterations.
Author:	Bavi, Prashant\|Prabhakaran, Sarita E\|Abubaker, Jehad\|Qadri, Zeeshan\|George, Thara\|Al-Sanea, Nasser\|Abduljabbar, Alaa\|Ashari, Luai H\|Alhomoud, Samar\|Al-Dayel, Fouad\|Hussain, Azhar R\|Uddin, Shahab\|Al-Kuraya, Khawla S
PMID:	20673328

235.
Journal:	Mol Cancer Ther. 2010 Aug;9(8):2196-207.
Title:	Gamma-tocotrienol promotes TRAIL-induced apoptosis through reactive oxygen species/extracellular signal-regulated kinase/p53-mediated upregulation of death receptors.
Author:	Kannappan, Ramaswamy\|Ravindran, Jayaraj\|Prasad, Sahdeo\|Sung, Bokyung\|Yadav, Vivek R\|Reuter, Simone\|Chaturvedi, Madan M\|Aggarwal, Bharat B
PMID:	20682650

236.
Journal:	Int J Oncol. 2010 Oct;37(4):1031-41.
Title:	Downregulation of active caspase 8 as a mechanism of acquired TRAIL resistance in mismatch repair-proficient colon carcinoma cell lines.
Author:	Van Geelen, Caroline M M\|Pennarun, Bodvael\|Ek, Wytske Boerma-Van\|Le, Phuong T K\|Spierings, Diana C J\|De Vries, Elisabeth G E\|De Jong, Steven
PMID:	20811726

237.
Journal:	J Biol Chem. 2010 Nov 12;285(46):35418-27.
Title:	Gossypol induces death receptor-5 through activation of the ROS-ERK-CHOP pathway and sensitizes colon cancer cells to TRAIL.
Author:	Sung, Bokyung\|Ravindran, Jayaraj\|Prasad, Sahdeo\|Pandey, Manoj K\|Aggarwal, Bharat B
PMID:	20837473

238.
Journal:	Expert Rev Anticancer Ther. 2010 Oct;10(10):1559-62.
Title:	Colorectal cancer chemoprevention: the potential of a selective approach.
Author:	Ben-Amotz, Oded\|Arber, Nadir\|Kraus, Sarah
PMID:	20942626

239.
Journal:	Anal Cell Pathol (Amst). 2010;33(5):229-44.
Title:	Inhibition of IGF-1R-dependent PI3K activation sensitizes colon cancer cells specifically to DR5-mediated apoptosis but not to rhTRAIL.
Author:	Pennarun, Bodvael\|Kleibeuker, Jan H\|Oenema, Tjitske\|Stegehuis, Janet H\|de Vries, Elisabeth G E\|de Jong, Steven
PMID:	20978316

240.
Journal:	Biomedica. 2010 Oct-Dec;30(4):577-86.
Title:	Implication of NF-kappaB and p53 in the expression of TRAIL-death receptors and apoptosis by apple procyanidins in human metastatic SW620 cells.
Author:	Maldonado, Maria Elena\|Bousserouel, Souad\|Gosse, Francine\|Lobstein, Annelise\|Raul, Francis
PMID:	21713362

241.
Journal:	Carcinogenesis. 2011 Jan;32(1):42-51.
Title:	Cisplatin and a potent platinum(IV) complex-mediated enhancement of TRAIL-induced cancer cells killing is associated with modulation of upstream events in the extrinsic apoptotic pathway.
Author:	Vondalova Blanarova, Olga\|Jelinkova, Iva\|Szoor, Arpad\|Skender, Belma\|Soucek, Karel\|Horvath, Viktor\|Vaculova, Alena\|Andera, Ladislav\|Sova, Petr\|Szollosi, Janos\|Hofmanova, Jirina\|Vereb, Gyorgy\|Kozubik, Alois
PMID:	21037225

242.
Journal:	Cancer Gene Ther. 2011 Apr;18(4):229-39.
Title:	TRAIL-transduced multipotent mesenchymal stromal cells (TRAIL-MSC) overcome TRAIL resistance in selected CRC cell lines in vitro and in vivo.
Author:	Mueller, L P\|Luetzkendorf, J\|Widder, M\|Nerger, K\|Caysa, H\|Mueller, T
PMID:	21037557

243.
Journal:	Cancer Res. 2011 Jan 15;71(2):538-49.
Title:	ROS and CHOP are critical for dibenzylideneacetone to sensitize tumor cells to TRAIL through induction of death receptors and downregulation of cell survival proteins.
Author:	Prasad, Sahdeo\|Yadav, Vivek R\|Ravindran, Jayaraj\|Aggarwal, Bharat B
PMID:	21127198

244.
Journal:	J Biol Chem. 2011 Feb 18;286(7):5546-57.
Title:	Ursolic acid, a pentacyclin triterpene, potentiates TRAIL-induced apoptosis through p53-independent up-regulation of death receptors: evidence for the role of reactive oxygen species and JNK.
Author:	Prasad, Sahdeo\|Yadav, Vivek R\|Kannappan, Ramaswamy\|Aggarwal, Bharat B
PMID:	21156789

245.
Journal:	J Pathol. 2011 Feb;223(3):378-89.
Title:	TNF-related apoptosis-inducing ligand cooperates with NSAIDs via activated Wnt signalling in (pre)malignant colon cells.
Author:	Heijink, Dianne M\|Jalving, Mathilde\|Oosterhuis, Dorenda\|Sloots, Ineke A\|Koster, Roelof\|Hollema, Harry\|Kleibeuker, Jan H\|Koornstra, Jan J\|de Vries, Elisabeth G E\|de Jong, Steven
PMID:	21171083

246.
Journal:	Cancer Gene Ther. 2011 May;18(5):336-45.
Title:	Treatment of patient tumor-derived colon cancer xenografts by a TRAIL gene-armed oncolytic adenovirus.
Author:	Zhou, W\|Zhu, H\|Chen, W\|Hu, X\|Pang, X\|Zhang, J\|Huang, X\|Fang, B\|He, C
PMID:	21183948

247.
Journal:	Cancer Lett. 2011 Feb 28;301(2):193-202.
Title:	Diosgenin induces death receptor-5 through activation of p38 pathway and promotes TRAIL-induced apoptosis in colon cancer cells.
Author:	Lepage, C\|Leger, D Y\|Bertrand, J\|Martin, F\|Beneytout, J L\|Liagre, B
PMID:	21195543

248.
Journal:	Cancer Lett. 2011 Mar 1;302(1):11-9.
Title:	Enhanced anti-tumor activity by the combination of TRAIL/Apo-2L and combretastatin A-4 against human colon cancer cells via induction of apoptosis in vitro and in vivo.
Author:	Zhang, Chong\|Wu, Rui\|Zhu, Hong\|Hu, Yong-zhou\|Jiang, Hai\|Lin, Neng-ming\|He, Qiao-jun\|Yang, Bo
PMID:	21236562

249.
Journal:	PLoS One. 2011 Jan 17;6(1):e16241.
Title:	TNFalpha cooperates with IFN-gamma to repress Bcl-xL expression to sensitize metastatic colon carcinoma cells to TRAIL-mediated apoptosis.
Author:	Liu, Feiyan\|Hu, Xiaolin\|Zimmerman, Mary\|Waller, Jennifer L\|Wu, Ping\|Hayes-Jordan, Andrea\|Lev, Dina\|Liu, Kebin
PMID:	21264227

250.
Journal:	BMC Cancer. 2011 Jan 27;11:39.
Title:	Modulation of TRAIL resistance in colon carcinoma cells: different contributions of DR4 and DR5.
Author:	van Geelen, Caroline Mm\|Pennarun, Bodvael\|Le, Phuong Tk\|de Vries, Elisabeth Ge\|de Jong, Steven
PMID:	21272366

251.
Journal:	Mol Biosyst. 2011 May;7(5):1512-22.
Title:	Synergistic anti-cancer effects via co-delivery of TNF-related apoptosis-inducing ligand (TRAIL/Apo2L) and doxorubicin using micellar nanoparticles.
Author:	Lee, Ashlynn L Z\|Dhillon, Sharon H K\|Wang, Yong\|Pervaiz, Shazib\|Fan, Weimin\|Yang, Yi Yan
PMID:	21350763

252.
Journal:	Carcinogenesis. 2011 May;32(5):723-31.
Title:	Lipid raft-dependent death receptor 5 (DR5) expression and activation are critical for ursodeoxycholic acid-induced apoptosis in gastric cancer cells.
Author:	Lim, Sung-Chul\|Duong, Hong-Quan\|Choi, Jeong Eun\|Lee, Tae-Bum\|Kang, Ju-Hee\|Oh, Seung Hyun\|Han, Song Iy
PMID:	21362627

253.
Journal:	Mol Cancer Ther. 2011 May;10(5):902-14.
Title:	Therapeutic potential and molecular mechanism of a novel, potent, nonpeptide, Smac mimetic SM-164 in combination with TRAIL for cancer treatment.
Author:	Lu, Jianfeng\|McEachern, Donna\|Sun, Haiying\|Bai, Longchuan\|Peng, Yuefeng\|Qiu, Su\|Miller, Rebecca\|Liao, Jinhui\|Yi, Han\|Liu, Meilan\|Bellail, Anita\|Hao, Chunhai\|Sun, Shi-Yong\|Ting, Adrian T\|Wang, Shaomeng
PMID:	21372226

254.
Journal:	Br J Pharmacol. 2011 Nov;164(5):1433-44.
Title:	Methyl jasmonate down-regulates survivin expression and sensitizes colon carcinoma cells towards TRAIL-induced cytotoxicity.
Author:	Raviv, Z\|Zilberberg, A\|Cohen, S\|Reischer-Pelech, D\|Horrix, C\|Berger, M R\|Rosin-Arbesfeld, R\|Flescher, E
PMID:	21486277

255.
Journal:	Mol Cancer. 2011 Apr 25;10:46.
Title:	High susceptibility of metastatic cells derived from human prostate and colon cancer cells to TRAIL and sensitization of TRAIL-insensitive primary cells to TRAIL by 4,5-dimethoxy-2-nitrobenzaldehyde.
Author:	Kim, Hak-Bong\|Kim, Mi-Ju\|Kim, Dae-Young\|Lee, Jae-Won\|Bae, Jae-Ho\|Kim, Dong-Wan\|Kang, Chi-Dug\|Kim, Sun-Hee
PMID:	21513580

256.
Journal:	Oncol Rep. 2011 Jul;26(1):109-14.
Title:	Lupulone triggers p38 MAPK-controlled activation of p53 and of the TRAIL receptor apoptotic pathway in human colon cancer-derived metastatic cells.
Author:	Lamy, Virginie\|Bousserouel, Souad\|Gosse, Francine\|Minker, Carole\|Lobstein, Annelise\|Raul, Francis
PMID:	21519792

257.
Journal:	Cell Oncol (Dordr). 2011 Jun;34(3):245-59.
Title:	Inhibition of IGF-1R-dependent PI3K activation sensitizes colon cancer cells specifically to DR5-mediated apoptosis but not to rhTRAIL.
Author:	Pennarun, Bodvael\|Kleibeuker, Jan H\|Oenema, Tjitske\|Stegehuis, Janet H\|de Vries, Elisabeth G E\|de Jong, Steven
PMID:	21538027

258.
Journal:	J Biol Chem. 2011 Jul 1;286(26):22982-90.
Title:	Sialylation of the Fas death receptor by ST6Gal-I provides protection against Fas-mediated apoptosis in colon carcinoma cells.
Author:	Swindall, Amanda F\|Bellis, Susan L
PMID:	21550977

259.
Journal:	Sci Transl Med. 2011 Jun 8;3(86):86ra50.
Title:	Off-target lapatinib activity sensitizes colon cancer cells through TRAIL death receptor up-regulation.
Author:	Dolloff, Nathan G\|Mayes, Patrick A\|Hart, Lori S\|Dicker, David T\|Humphreys, Robin\|El-Deiry, Wafik S
PMID:	21653830

260.
Journal:	Gastroenterology. 2011 Aug;141(2):663-73.
Title:	Oxaliplatin sensitizes human colon cancer cells to TRAIL through JNK-dependent phosphorylation of Bcl-xL.
Author:	El Fajoui, Zineb\|Toscano, Florent\|Jacquemin, Guillaume\|Abello, Jacques\|Scoazec, Jean-Yves\|Micheau, Olivier\|Saurin, Jean-Christophe
PMID:	21683075

261.
Journal:	PLoS One. 2011;6(6):e21632.
Title:	Selective BRAFV600E inhibitor PLX4720, requires TRAIL assistance to overcome oncogenic PIK3CA resistance.
Author:	Oikonomou, Eftychia\|Koc, Michal\|Sourkova, Vladimira\|Andera, Ladislav\|Pintzas, Alexander
PMID:	21738740

262.
Journal:	Apoptosis. 2011 Oct;16(10):1042-53.
Title:	Silibinin triggers apoptotic signaling pathways and autophagic survival response in human colon adenocarcinoma cells and their derived metastatic cells.
Author:	Kauntz, Henriette\|Bousserouel, Souad\|Gosse, Francine\|Raul, Francis
PMID:	21779837

263.
Journal:	Mol Cancer Ther. 2011 Oct;10(10):1969-81.
Title:	2-methoxy-5-amino-N-hydroxybenzamide sensitizes colon cancer cells to TRAIL-induced apoptosis by regulating death receptor 5 and survivin expression.
Author:	Stolfi, Carmine\|Caruso, Roberta\|Franze, Eleonora\|Rizzo, Angelamaria\|Rotondi, Angela\|Monteleone, Ivan\|Fantini, Massimo Claudio\|Pallone, Francesco\|Monteleone, Giovanni
PMID:	21817114

264.
Journal:	Biomaterials. 2011 Nov;32(33):8529-37.
Title:	PEGylated TNF-related apoptosis-inducing ligand (TRAIL) for effective tumor combination therapy.
Author:	Jiang, Hai Hua\|Kim, Tae Hyung\|Lee, Seulki\|Chen, Xiaoyuan\|Youn, Yu Seok\|Lee, Kang Choon
PMID:	21855130

265.
Journal:	Cancer Res. 2011 Nov 1;71(21):6807-16.
Title:	Verticillin A overcomes apoptosis resistance in human colon carcinoma through DNA methylation-dependent upregulation of BNIP3.
Author:	Liu, Feiyan\|Liu, Qianqian\|Yang, Dafeng\|Bollag, Wendy B\|Robertson, Keith\|Wu, Ping\|Liu, Kebin
PMID:	21911457

266.
Journal:	Eur J Pharm Sci. 2011 Nov 20;44(4):479-86.
Title:	Novel selective Cox-2 inhibitors induce apoptosis in Caco-2 colorectal carcinoma cell line.
Author:	Entezari Heravi, Reza\|Hadizadeh, Farzin\|Sankian, Mojtaba\|Tavakol Afshari, Jalil\|Taghdisi, Seyed Mohammad\|Jafarian, Hanieh\|Behravan, Javad
PMID:	21939759

267.
Journal:	Anticancer Res. 2011 Oct;31(10):3385-94.
Title:	Low-dose combinations of LBH589 and TRAIL can overcome TRAIL-resistance in colon cancer cell lines.
Author:	Lee, Sang-Cheol\|Cheong, Hee-Jeong\|Kim, Sook-Ja\|Yoon, Jina\|Kim, Han Jo\|Kim, Kyoung Ha\|Kim, Se Hyoung\|Kim, Hyun Jung\|Bae, Sang Byung\|Kim, Chan-Kyu\|Lee, Namsu\|Lee, Kyu Taeg\|Park, Sung Kyu\|Hong, Dae Sik\|Park, Hee Sook\|Won, Jong-Ho
PMID:	21965751

268.
Journal:	Am J Pathol. 2011 Dec;179(6):3032-44.
Title:	Coexpression of activated c-Met and death receptor 5 predicts better survival in colorectal carcinoma.
Author:	Uddin, Shahab\|Hussain, Azhar R\|Ahmed, Maqbool\|Al-Sanea, Nasser\|Abduljabbar, Alaa\|Ashari, Luai H\|Alhomoud, Samar\|Al-Dayel, Fouad\|Bavi, Prashant\|Al-Kuraya, Khawla S
PMID:	21978492

269.
Journal:	J Biol Chem. 2011 Dec 16;286(50):43123-33.
Title:	GDP-mannose-4,6-dehydratase (GMDS) deficiency renders colon cancer cells resistant to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor- and CD95-mediated apoptosis by inhibiting complex II formation.
Author:	Moriwaki, Kenta\|Shinzaki, Shinichiro\|Miyoshi, Eiji
PMID:	22027835

270.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2011 Oct;14(10):803-6.
Title:	[Study of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptotic and inflammatory gene expressions in colon cancer cell line].
Author:	Yu, Hong-bin\|Zhu, Wei\|Dai, Chuang
PMID:	22030783

271.
Journal:	J Cell Physiol. 2012 Feb;227(2):630-8.
Title:	TRAIL up-regulation must be accompanied by a reciprocal PKCepsilon down-regulation during differentiation of colonic epithelial cell: implications for colorectal cancer cell differentiation.
Author:	Gobbi, Giuliana\|Di Marcantonio, Daniela\|Micheloni, Cristina\|Carubbi, Cecilia\|Galli, Daniela\|Vaccarezza, Mauro\|Bucci, Giovanna\|Vitale, Marco\|Mirandola, Prisco
PMID:	21465464

272.
Journal:	Br J Pharmacol. 2012 Feb;165(3):741-53.
Title:	Cardamonin sensitizes tumour cells to TRAIL through ROS- and CHOP-mediated up-regulation of death receptors and down-regulation of survival proteins.
Author:	Yadav, Vivek R\|Prasad, Sahdeo\|Aggarwal, Bharat B
PMID:	21797841

273.
Journal:	Oncogene. 2012 Apr 26;31(17):2210-21.
Title:	Key role of ATF3 in p53-dependent DR5 induction upon DNA damage of human colon cancer cells.
Author:	Taketani, K\|Kawauchi, J\|Tanaka-Okamoto, M\|Ishizaki, H\|Tanaka, Y\|Sakai, T\|Miyoshi, J\|Maehara, Y\|Kitajima, S
PMID:	21927023

274.
Journal:	Mol Ther. 2012 Jan;20(1):46-53.
Title:	2A peptide-based, lentivirus-mediated anti-death receptor 5 chimeric antibody expression prevents tumor growth in nude mice.
Author:	Li, Meng\|Wu, Yaomin\|Qiu, Yuhe\|Yao, Zhenyu\|Liu, Shilian\|Liu, Yanxin\|Shi, Juan\|Zheng, Dexian
PMID:	21934654

275.
Journal:	Cell Death Differ. 2012 Mar;19(3):523-33.
Title:	Cell-surface galectin-3 confers resistance to TRAIL by impeding trafficking of death receptors in metastatic colon adenocarcinoma cells.
Author:	Mazurek, N\|Byrd, J C\|Sun, Y\|Hafley, M\|Ramirez, K\|Burks, J\|Bresalier, R S
PMID:	21941373

276.
Journal:	Cancer Lett. 2012 Feb 1;315(1):69-77.
Title:	Nanoliposome-mediated FL/TRAIL double-gene therapy for colon cancer: in vitro and in vivo evaluation.
Author:	Sun, Nian-feng\|Meng, Qing-yi\|Tian, Ai-ling\|Hu, San-yuan\|Wang, Rui-hua\|Liu, Zhao-xuan\|Xu, Li
PMID:	22071223

277.
Journal:	Apoptosis. 2012 Mar;17(3):236-47.
Title:	Pleomorphic adenoma gene-like 2 regulates expression of the p53 family member, p73, and induces cell cycle block and apoptosis in human promonocytic U937 cells.
Author:	Hanks, Tracey S\|Gauss, Katherine A
PMID:	22076304

278.
Journal:	J Biol Chem. 2012 Jan 2;287(1):641-9.
Title:	Wogonin and related natural flavones overcome tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) protein resistance of tumors by down-regulation of c-FLIP protein and up-regulation of TRAIL receptor 2 expression.
Author:	Ding, Jie\|Polier, Gernot\|Kohler, Rebecca\|Giaisi, Marco\|Krammer, Peter H\|Li-Weber, Min
PMID:	22086925

279.
Journal:	J Cell Biochem. 2012 May;113(5):1547-58.
Title:	Hyperthermia-enhanced TRAIL- and mapatumumab-induced apoptotic death is mediated through mitochondria in human colon cancer cells.
Author:	Song, Xinxin\|Kim, Han-Cheon\|Kim, Seog-Young\|Basse, Per\|Park, Bae-Hang\|Lee, Byeong-Chel\|Lee, Yong J
PMID:	22174016

280.
Journal:	Biochem Pharmacol. 2012 May 1;83(9):1217-28.
Title:	Acute sensitization of colon cancer cells to inflammatory cytokines by prophase arrest.
Author:	Kuratnik, Anton\|Senapati, Virginia E\|Verma, Rajeev\|Mellone, Barbara G\|Vella, Anthony T\|Giardina, Charles
PMID:	22306067

281.
Journal:	Phytother Res. 2012 Oct;26(10):1541-6.
Title:	3-O-acetyloleanolic acid induces apoptosis in human colon carcinoma HCT-116 cells.
Author:	Yoo, Ki Hyun\|Park, Jong-Hwa\|Cui, En Ji\|Kim, Kyung Il\|Kim, Joo Yun\|Kim, Jiyoung\|Hong, Seong Gil\|Baek, Nam In\|Chung, In Sik
PMID:	22359244

282.
Journal:	PLoS One. 2012;7(2):e31762.
Title:	Sub-lethal irradiation of human colorectal tumor cells imparts enhanced and sustained susceptibility to multiple death receptor signaling pathways.
Author:	Ifeadi, Victoria\|Garnett-Benson, Charlie
PMID:	22389673

283.
Journal:	Int Immunopharmacol. 2012 May;13(1):37-45.
Title:	Ad-KDRscFv:sTRAIL displays a synergistic antitumor effect without obvious cytotoxicity to normal tissues.
Author:	Yang, Liuqin\|Guo, Jun\|Wang, Jun\|Wan, Shunmei\|Yang, Shiming\|Wang, Rongquan\|Chen, Wensheng\|Peng, Guiyong\|Fang, Dianchun
PMID:	22406047

284.
Journal:	J Biomed Sci. 2012 Mar 30;19:35.
Title:	STI571 reduces TRAIL-induced apoptosis in colon cancer cells: c-Abl activation by the death receptor leads to stress kinase-dependent cell death.
Author:	Huang, Duen-Yi\|Chao, Yee\|Tai, Ming-Hui\|Yu, Yang-Hao\|Lin, Wan-Wan
PMID:	22462553

285.
Journal:	Biochem Biophys Res Commun. 2012 Apr 20;420(4):913-7.
Title:	Hypoxia-inducible factor 1 regulated ARC expression mediated hypoxia induced inactivation of the intrinsic death pathway in p53 deficient human colon cancer cells.
Author:	Ao, Jin-e\|Kuang, Liang-hong\|Zhou, Yu\|Zhao, Rong\|Yang, Chang-ming
PMID:	22475487

286.
Journal:	Cell Death Dis. 2012 Apr 12;3:e295.
Title:	Superior antitumoral activity of dimerized targeted single-chain TRAIL fusion proteins under retention of tumor selectivity.
Author:	Siegemund, M\|Pollak, N\|Seifert, O\|Wahl, K\|Hanak, K\|Vogel, A\|Nussler, A K\|Gottsch, D\|Munkel, S\|Bantel, H\|Kontermann, R E\|Pfizenmaier, K
PMID:	22495350

287.
Journal:	Apoptosis. 2012 Aug;17(8):797-809.
Title:	The flavonolignan silibinin potentiates TRAIL-induced apoptosis in human colon adenocarcinoma and in derived TRAIL-resistant metastatic cells.
Author:	Kauntz, Henriette\|Bousserouel, Souad\|Gosse, Francine\|Raul, Francis
PMID:	22555452

288.
Journal:	Cancer Lett. 2012 Nov 1;324(1):98-108.
Title:	Blocking p38/ERK crosstalk affects colorectal cancer growth by inducing apoptosis in vitro and in preclinical mouse models.
Author:	Chiacchiera, Fulvio\|Grossi, Valentina\|Cappellari, Marianna\|Peserico, Alessia\|Simonatto, Marta\|Germani, Aldo\|Russo, Silvana\|Moyer, Mary P\|Resta, Nicoletta\|Murzilli, Stefania\|Simone, Cristiano
PMID:	22579651

289.
Journal:	Eur J Pharmacol. 2012 Aug 5;688(1-3):14-21.
Title:	The natural alkaloid berberine targets multiple pathways to induce cell death in cultured human colon cancer cells.
Author:	Chidambara Murthy, Kotamballi N\|Jayaprakasha, Guddadarangavvanahally K\|Patil, Bhimanagouda S
PMID:	22617025

290.
Journal:	PLoS One. 2012;7(5):e37452.
Title:	Exosome-related multi-pass transmembrane protein TSAP6 is a target of rhomboid protease RHBDD1-induced proteolysis.
Author:	Wan, Chunhua\|Fu, Jun\|Wang, Yong\|Miao, Shiying\|Song, Wei\|Wang, Linfang
PMID:	22624035

291.
Journal:	Mol Pharm. 2012 Aug 6;9(8):2219-27.
Title:	Inducing apoptosis in rolling cancer cells: a combined therapy with aspirin and immobilized TRAIL and E-selectin.
Author:	Rana, Kuldeepsinh\|Reinhart-King, Cynthia A\|King, Michael R
PMID:	22724630

292.
Journal:	Clin Lab. 2012;58(5-6):501-5.
Title:	IL8 and serum soluble TRAIL levels following anti-VEGF monoclonal antibody treatment in patients with metastatic colon cancer.
Author:	Kargi, Aysegul\|Yalcin, Arzu Didem\|Erin, Nuray\|Savas, Burhan\|Polat, H Huseyin\|Gorczynski, Reginald M
PMID:	22783581

293.
Journal:	Cell Cycle. 2012 Sep 1;11(17):3312-23.
Title:	Mitomycin C potentiates TRAIL-induced apoptosis through p53-independent upregulation of death receptors: evidence for the role of c-Jun N-terminal kinase activation.
Author:	Cheng, Hairong\|Hong, Bo\|Zhou, Lanlan\|Allen, Joshua E\|Tai, Guihua\|Humphreys, Robin\|Dicker, David T\|Liu, Yingqiu Y\|El-Deiry, Wafik S
PMID:	22895172

294.
Journal:	Free Radic Biol Med. 2012 Nov 15;53(10):1977-87.
Title:	Capsazepine, a TRPV1 antagonist, sensitizes colorectal cancer cells to apoptosis by TRAIL through ROS-JNK-CHOP-mediated upregulation of death receptors.
Author:	Sung, Bokyung\|Prasad, Sahdeo\|Ravindran, Jayaraj\|Yadav, Vivek R\|Aggarwal, Bharat B
PMID:	22922338

295.
Journal:	Int J Mol Med. 2012 Nov;30(5):1087-94.
Title:	The synergistic effects of low-dose irinotecan and TRAIL on TRAIL-resistant HT-29 colon carcinoma in vitro and in vivo.
Author:	Zhu, Hong\|Zhao, Fen\|Yu, Shuijing\|He, Jianping\|Deng, Licong\|Yi, Cheng\|Huang, Ying
PMID:	22922573

296.
Journal:	Int J Mol Sci. 2012;13(7):7886-901.
Title:	Molecular targets of TRAIL-sensitizing agents in colorectal cancer.
Author:	Stolfi, Carmine\|Pallone, Francesco\|Monteleone, Giovanni
PMID:	22942679

297.
Journal:	PLoS One. 2012;7(9):e45462.
Title:	Activating mutations in beta-catenin in colon cancer cells alter their interaction with macrophages; the role of snail.
Author:	Kaler, Pawan\|Augenlicht, Leonard\|Klampfer, Lidija
PMID:	23029025

298.
Journal:	Oncol Res. 2012;20(1):15-24.
Title:	TLR4 signaling promotes immune escape of human colon cancer cells by inducing immunosuppressive cytokines and apoptosis resistance.
Author:	Tang, Xiaoyan\|Zhu, Youqing
PMID:	23035361

299.
Journal:	Biochem Biophys Res Commun. 2012 Nov 9;428(1):185-90.
Title:	Carnitine sensitizes TRAIL-resistant cancer cells to TRAIL-induced apoptotic cell death through the up-regulation of Bax.
Author:	Park, So Jung\|Park, Seong Ho\|Kim, Joo-Oh\|Kim, Jung Ho\|Park, So Jung\|Hwang, Jung Jin\|Jin, Dong-Hoon\|Jeong, Seong-Yun\|Lee, Seung Jin\|Kim, Jin Cheon\|Kim, Inki\|Cho, Dong-Hyung
PMID:	23068102

300.
Journal:	BMC Cell Biol. 2012 Oct 31;13:27.
Title:	Phosphorylation of p68 RNA helicase by p38 MAP kinase contributes to colon cancer cells apoptosis induced by oxaliplatin.
Author:	Dey, Heena\|Liu, Zhi-Ren
PMID:	23110695

301.
Journal:	Cancer Biother Radiopharm. 2012 Nov;27(9):577-81.
Title:	Bax is essential for death receptor-mediated apoptosis in human colon cancer cells.
Author:	Zhu, Shunqin\|Li, Tai\|Tan, Juan\|Yan, Xiaomin\|Zhang, Dunke\|Zheng, Chunqin\|Chen, Yibiao\|Xiang, Zhonghuai\|Cui, Hongjuan
PMID:	23113596

302.
Journal:	Clin Lab. 2012;58(9-10):1103-7.
Title:	Erratum to "IL8 and serum soluble TRAIL levels following anti-VEGF monoclonal antibody treatment in patients with metastatic colon cancer" [Clin. Lab. 2012; 58:501-505].
Author:	Kargi, Aysegul\|Yalcin, Arzu Didem\|Erin, Nuray\|Savas, Burhan\|Polat, H Huseyin\|Gorczynski, Reginald M
PMID:	23163132

303.
Journal:	PLoS One. 2012;7(12):e51654.
Title:	Microsatellite instability, KRAS mutations and cellular distribution of TRAIL-receptors in early stage colorectal cancer.
Author:	Kriegl, Lydia\|Jung, Andreas\|Horst, David\|Rizzani, Antonia\|Jackstadt, Rene\|Hermeking, Heiko\|Gallmeier, Eike\|Gerbes, Alexander L\|Kirchner, Thomas\|Goke, Burkhard\|De Toni, Enrico N
PMID:	23284732

304.
Journal:	J Cell Physiol. 2013 Apr;228(4):764-72.
Title:	Inhibition of PRC2 histone methyltransferase activity increases TRAIL-mediated apoptosis sensitivity in human colon cancer cells.
Author:	Benoit, Yannick D\|Laursen, Kristian B\|Witherspoon, Mavee S\|Lipkin, Steven M\|Gudas, Lorraine J
PMID:	23001792

305.
Journal:	J Pathol. 2013 Feb;229(3):410-21.
Title:	Targeting FLIP and Mcl-1 using a combination of aspirin and sorafenib sensitizes colon cancer cells to TRAIL.
Author:	Pennarun, Bodvael\|Kleibeuker, Jan H\|Boersma-van Ek, Wytske\|Kruyt, Frank A E\|Hollema, Harry\|de Vries, Elisabeth G E\|de Jong, Steven
PMID:	23132258

306.
Journal:	Oncol Rep. 2013 Feb;29(2):474-80.
Title:	Casticin, a flavonoid, potentiates TRAIL-induced apoptosis through modulation of anti-apoptotic proteins and death receptor 5 in colon cancer cells.
Author:	Tang, San-Yuan\|Zhong, Mei-Zuo\|Yuan, Guang-Jin\|Hou, Su-Ping\|Yin, Lei-Lan\|Jiang, Hao\|Yu, Zheng-Upsilonang
PMID:	23135489

307.
Journal:	Cell Death Dis. 2013 Feb 21;4:e503.
Title:	Delivery of sTRAIL variants by MSCs in combination with cytotoxic drug treatment leads to p53-independent enhanced antitumor effects.
Author:	Yu, R\|Deedigan, L\|Albarenque, S M\|Mohr, A\|Zwacka, R M
PMID:	23429289

308.
Journal:	Apoptosis. 2013 Jun;18(6):739-50.
Title:	The plant alkaloid and anti-leukemia drug homoharringtonine sensitizes resistant human colorectal carcinoma cells to TRAIL-induced apoptosis via multiple mechanisms.
Author:	Beranova, Lenka\|Pombinho, Antonio R\|Spegarova, Jarmila\|Koc, Michal\|Klanova, Magdalena\|Molinsky, Jan\|Klener, Pavel\|Bartunek, Petr\|Andera, Ladislav
PMID:	23456623

309.
Journal:	Cancer Lett. 2013 Jul 28;335(2):431-40.
Title:	The PEA-15/PED protein regulates cellular survival and invasiveness in colorectal carcinomas.
Author:	Funke, Verena\|Lehmann-Koch, Judith\|Bickeboller, Michele\|Benner, Axel\|Tagscherer, Katrin E\|Grund, Kerstin\|Pfeifer, Marco\|Herpel, Esther\|Schirmacher, Peter\|Chang-Claude, Jenny\|Brenner, Hermann\|Hoffmeister, Michael\|Roth, Wilfried
PMID:	23481023

310.
Journal:	J Cancer Res Clin Oncol. 2013 Jul;139(7):1169-78.
Title:	Microarray analyses reveal liver metastasis-related genes in metastatic colorectal cancer cell model.
Author:	Chen, Qiang\|Chen, Lei\|Zhao, Ren\|Yang, Xiao-dong\|Imran, Khan\|Xing, Chun-gen
PMID:	23563852

311.
Journal:	Free Radic Biol Med. 2013 Oct;63:280-90.
Title:	Aldose reductase inhibition enhances TRAIL-induced human colon cancer cell apoptosis through AKT/FOXO3a-dependent upregulation of death receptors.
Author:	Shoeb, Mohammad\|Ramana, Kota V\|Srivastava, Satish K
PMID:	23732517

312.
Journal:	Int J Oncol. 2013 Aug;43(2):394-404.
Title:	Methanolic extract of white asparagus shoots activates TRAIL apoptotic death pathway in human cancer cells and inhibits colon carcinogenesis in a preclinical model.
Author:	Bousserouel, Souad\|Le Grandois, Julie\|Gosse, Francine\|Werner, Dalal\|Barth, Stephan W\|Marchioni, Eric\|Marescaux, Jacques\|Raul, Francis
PMID:	23754197

313.
Journal:	PLoS One. 2013 Jun 6;8(6):e65145.
Title:	Chemotherapy sensitizes colon cancer initiating cells to Vgamma9Vdelta2 T cell-mediated cytotoxicity.
Author:	Todaro, Matilde\|Orlando, Valentina\|Cicero, Giuseppe\|Caccamo, Nadia\|Meraviglia, Serena\|Stassi, Giorgio\|Dieli, Francesco
PMID:	23762301

314.
Journal:	Cancer Biol Ther. 2013 Aug;14(8):711-9.
Title:	FOLFIRI plus dulanermin (rhApo2L/TRAIL) in a patient with BRAF-mutant metastatic colon cancer.
Author:	Lim, Bora\|Scicchitano, Angelique\|Beachler, Cheryl\|Gusani, Niraj\|Sarwani, Nabeel\|Yang, Zhaohai\|Staveley-O'Carroll, Kevin\|Ashkenazi, Avi\|Portera, Chia\|El-Deiry, Wafik S
PMID:	23792567

315.
Journal:	Oncotarget. 2013 Aug;4(8):1185-98.
Title:	Combining trail with PI3 kinase or HSP90 inhibitors enhances apoptosis in colorectal cancer cells via suppression of survival signaling.
Author:	Saturno, Grazia\|Valenti, Melanie\|De Haven Brandon, Alexis\|Thomas, George V\|Eccles, Suzanne\|Clarke, Paul A\|Workman, Paul
PMID:	23852390

316.
Journal:	Oncol Rep. 2013 Nov;30(5):2379-84.
Title:	Ibuprofen enhances TRAIL-induced apoptosis through DR5 upregulation.
Author:	Todo, Momoko\|Horinaka, Mano\|Tomosugi, Mitsuhiro\|Tanaka, Ryoichi\|Ikawa, Haruna\|Sowa, Yoshihiro\|Ishikawa, Hideki\|Fujiwara, Hitoshi\|Otsuji, Eigo\|Sakai, Toshiyuki
PMID:	24002210

317.
Journal:	Clin Cancer Res. 2013 Nov 1;19(21):5984-93.
Title:	Molecular imaging of death receptor 5 occupancy and saturation kinetics in vivo by humanized monoclonal antibody CS-1008.
Author:	Burvenich, Ingrid J G\|Lee, Fook T\|Cartwright, Glenn A\|O'Keefe, Graeme J\|Makris, Dahna\|Cao, Diana\|Gong, Sylvia\|Chueh, Anderly C\|Mariadason, John M\|Brechbiel, Martin W\|Beckman, Robert A\|Fujiwara, Kosaku\|von Roemeling, Reinhard\|Scott, Andrew M
PMID:	24045184

318.
Journal:	PLoS One. 2013 Oct 3;8(10):e74140.
Title:	Sporadic colorectal cancer development shows rejuvenescence regarding epithelial proliferation and apoptosis.
Author:	Leiszter, Katalin\|Galamb, Orsolya\|Sipos, Ferenc\|Krenacs, Tibor\|Veres, Gabor\|Wichmann, Barnabas\|Kalmar, Alexandra\|Patai, Arpad V\|Toth, Kinga\|Valcz, Gabor\|Molnar, Bela\|Tulassay, Zsolt
PMID:	24098334

319.
Journal:	Oncol Rep. 2013 Dec;30(6):2845-51.
Title:	Protein-bound polysaccharide-K augments the anticancer effect of fluoropyrimidine derivatives possibly by lowering dihydropyrimidine dehydrogenase expression in gastrointestinal cancers.
Author:	Mekata, Eiji\|Murata, Satoshi\|Sonoda, Hiromichi\|Shimizu, Tomoharu\|Umeda, Tomoko\|Shiomi, Hisanori\|Naka, Shigeyuki\|Yamamoto, Hiroshi\|Abe, Hajime\|Edamatsu, Takeo\|Fujieda, Ayako\|Fujioka, Masaki\|Wada, Tsutomu\|Tani, Tohru
PMID:	24100378

320.
Journal:	Cancer Sci. 2013 Dec;104(12):1632-9.
Title:	Amurensin G enhances the susceptibility to tumor necrosis factor-related apoptosis-inducing ligand-mediated cytotoxicity of cancer stem-like cells of HCT-15 cells.
Author:	Lee, Su-Hoon\|Kim, Mi-Ju\|Kim, Dong-Wan\|Kang, Chi-Dug\|Kim, Sun-Hee
PMID:	24118446

321.
Journal:	Cancer. 2013 Dec 15;119(24):4290-8.
Title:	TRAIL receptor agonist conatumumab with modified FOLFOX6 plus bevacizumab for first-line treatment of metastatic colorectal cancer: A randomized phase 1b/2 trial.
Author:	Fuchs, Charles S\|Fakih, Marwan\|Schwartzberg, Lee\|Cohn, Allen L\|Yee, Lorrin\|Dreisbach, Luke\|Kozloff, Mark F\|Hei, Yong-jiang\|Galimi, Francesco\|Pan, Yang\|Haddad, Vincent\|Hsu, Cheng-Pang\|Sabin, Antony\|Saltz, Leonard
PMID:	24122767

322.
Journal:	Med Sci Monit. 2013 Oct 21;19:875-82.
Title:	Level of TNF-related apoptosis-inducing-ligand and CXCL8 correlated with 2-[18F]Fluoro-2-deoxy-D-glucose uptake in anti-VEGF treated colon cancers.
Author:	Celik, Betul\|Yalcin, Arzu Didem\|Bisgin, Atil\|Dimitrakopoulou-Strauss, Antonia\|Kargi, Aysegul\|Strauss, Ludwig G
PMID:	24145180

323.
Journal:	Curr Colorectal Cancer Rep. 2013 Dec;9(4).
Title:	Role of apoptosis in colon cancer biology, therapy, and prevention.
Author:	Zhang, Lin\|Yu, Jian
PMID:	24273467

324.
Journal:	New J Phys. 2013 Jan 18;15:015008.
Title:	Fluid Shear Stress Sensitizes Cancer Cells to Receptor-Mediated Apoptosis via Trimeric Death Receptors.
Author:	Mitchell, Michael J\|King, Michael R
PMID:	25110459

325.
Journal:	Oncol Rep. 2014 Feb;31(2):947-54.
Title:	Peroxisome proliferator-activated receptor gamma ligand troglitazone and TRAIL synergistically induce apoptosis.
Author:	Koyama, Makoto\|Sowa, Yoshihiro\|Horinaka, Mano\|Goda, Ahmed E\|Fujiwara, Jun\|Sakai, Toshiyuki
PMID:	24276615

326.
Journal:	Br J Cancer. 2014 Feb 4;110(3):656-67.
Title:	p53-dependent and p53-independent anticancer effects of different histone deacetylase inhibitors.
Author:	Sonnemann, J\|Marx, C\|Becker, S\|Wittig, S\|Palani, C D\|Kramer, O H\|Beck, J F
PMID:	24281001

327.
Journal:	J Biol Chem. 2014 Jan 24;289(4):1917-29.
Title:	Modulation of nuclear factor E2-related factor-2 (Nrf2) activation by the stress response gene immediate early response-3 (IER3) in colonic epithelial cells: a novel mechanism of cellular adaption to inflammatory stress.
Author:	Stachel, Imke\|Geismann, Claudia\|Aden, Konrad\|Deisinger, Florian\|Rosenstiel, Philip\|Schreiber, Stefan\|Sebens, Susanne\|Arlt, Alexander\|Schafer, Heiner
PMID:	24311782

328.
Journal:	J Biol Chem. 2014 Jan 31;289(5):2978-91.
Title:	Novel piperazine-based compounds inhibit microtubule dynamics and sensitize colon cancer cells to tumor necrosis factor-induced apoptosis.
Author:	Chopra, Avijeet\|Anderson, Amy\|Giardina, Charles
PMID:	24338023

329.
Journal:	Carcinogenesis. 2014 May;35(5):1092-9.
Title:	Regulation of TRAIL receptor expression by beta-catenin in colorectal tumours.
Author:	Jalving, M\|Heijink, D M\|Koornstra, J J\|Boersma-van Ek, W\|Zwart, N\|Wesseling, J\|Sluiter, W J\|de Vries, E G E\|Kleibeuker, J H\|de Jong, S
PMID:	24379239

330.
Journal:	Biochem Biophys Res Commun. 2014 Mar 7;445(2):320-6.
Title:	Role of ATF3 in synergistic cancer cell killing by a combination of HDAC inhibitors and agonistic anti-DR5 antibody through ER stress in human colon cancer cells.
Author:	Liu, Jia\|Edagawa, Makoto\|Goshima, Hiroto\|Inoue, Makoto\|Yagita, Hideo\|Liu, Zhonghui\|Kitajima, Shigetaka
PMID:	24530917

331.
Journal:	Clin Lab. 2014;60(2):339-40.
Title:	Blood eosinophil and platelet levels, proteomics patterns of trail and CXCL8 correlated with survival in bevacizumab treated metastatic colon cancers.
Author:	Yalcin, Arzu D\|Kargi, Aysegul\|Gumuslu, Saadet
PMID:	24660552

332.
Journal:	Oncol Lett. 2014 May;7(5):1728-1732.
Title:	Laminarin-induced apoptosis in human colon cancer LoVo cells.
Author:	Ji, Chen-Feng\|Ji, Yu-Bin
PMID:	24765209

333.
Journal:	Phytomedicine. 2014 Jul-Aug;21(8-9):1070-7.
Title:	Propolis cinnamic acid derivatives induce apoptosis through both extrinsic and intrinsic apoptosis signaling pathways and modulate of miRNA expression.
Author:	Kumazaki, Minami\|Shinohara, Haruka\|Taniguchi, Kohei\|Yamada, Nami\|Ohta, Shozo\|Ichihara, Kenji\|Akao, Yukihiro
PMID:	24854570

334.
Journal:	Mediators Inflamm. 2014;2014:848632.
Title:	Interaction of dietary fatty acids with tumour necrosis factor family cytokines during colon inflammation and cancer.
Author:	Hofmanova, Jirina\|Strakova, Nicol\|Vaculova, Alena Hyrslova\|Tylichova, Zuzana\|Safarikova, Barbora\|Skender, Belma\|Kozubik, Alois
PMID:	24876678

335.
Journal:	Food Chem Toxicol. 2014 Sep;71:51-9.
Title:	Ilimaquinone induces death receptor expression and sensitizes human colon cancer cells to TRAIL-induced apoptosis through activation of ROS-ERK/p38 MAPK-CHOP signaling pathways.
Author:	Do, Minh Truong\|Na, MinKyun\|Kim, Hyung Gyun\|Khanal, Tilak\|Choi, Jae Ho\|Jin, Sun Woo\|Oh, Seok Hoon\|Hwang, In Hyun\|Chung, Young Chul\|Kim, Hee Suk\|Jeong, Tae Cheon\|Jeong, Hye Gwang
PMID:	24930757

336.
Journal:	J Biol Chem. 2014 Aug 1;289(31):21544-61.
Title:	Role of activating transcription factor 3 (ATF3) in endoplasmic reticulum (ER) stress-induced sensitization of p53-deficient human colon cancer cells to tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis through up-re
Author:	Edagawa, Makoto\|Kawauchi, Junya\|Hirata, Manabu\|Goshima, Hiroto\|Inoue, Makoto\|Okamoto, Tatsuro\|Murakami, Akira\|Maehara, Yoshihiko\|Kitajima, Shigetaka
PMID:	24939851

337.
Journal:	Biochim Biophys Acta. 2014 Sep;1841(9):1308-17.
Title:	DHA-mediated enhancement of TRAIL-induced apoptosis in colon cancer cells is associated with engagement of mitochondria and specific alterations in sphingolipid metabolism.
Author:	Skender, Belma\|Hofmanova, Jirina\|Slavik, Josef\|Jelinkova, Iva\|Machala, Miroslav\|Moyer, Mary Pat\|Kozubik, Alois\|Hyrslova Vaculova, Alena
PMID:	24953781

338.
Journal:	Sci Rep. 2014 Aug 8;4:6000.
Title:	Myeloid zinc finger 1 mediates sulindac sulfide-induced upregulation of death receptor 5 of human colon cancer cells.
Author:	Horinaka, Mano\|Yoshida, Tatsushi\|Tomosugi, Mitsuhiro\|Yasuda, Shusuke\|Sowa, Yoshihiro\|Sakai, Toshiyuki
PMID:	25102912

339.
Journal:	Apoptosis. 2014 Oct;19(10):1532-44.
Title:	Urokinase-type plasminogen activator receptor regulates apoptotic sensitivity of colon cancer HCT116 cell line to TRAIL via JNK-p53 pathway.
Author:	Liu, Xiufeng\|Qiu, Fan\|Liu, Zhipeng\|Lan, Yan\|Wang, Kai\|Zhou, Ping-Kun\|Wang, Yao\|Hua, Zi-Chun
PMID:	25113506

340.
Journal:	Apoptosis. 2014 Nov;19(11):1603-15.
Title:	Role of Bcl-xL/Beclin-1 in synergistic apoptotic effects of secretory TRAIL-armed adenovirus in combination with mitomycin C and hyperthermia on colon cancer cells.
Author:	Kim, Seog-Young\|Lee, Dae-Hee\|Song, Xinxin\|Bartlett, David L\|Kwon, Yong Tae\|Lee, Yong J
PMID:	25156145

341.
Journal:	BMC Surg. 2014 Aug 27;14:58.
Title:	Randomized controlled multicentre study comparing biological mesh closure of the pelvic floor with primary perineal wound closure after extralevator abdominoperineal resection for rectal cancer (BIOPEX-study).
Author:	Musters, Gijsbert D\|Bemelman, Willem A\|Bosker, Robbert J I\|Burger, Jacobus W A\|van Duijvendijk, Peter\|van Etten, Boudewijn\|van Geloven, Anna A W\|de Graaf, Eelco J R\|Hoff, Christiaan\|de Korte, Niels\|Leijtens, Jeroen W A\|Rutten, Harm J T\|Singh, Baljit\|van d
PMID:	25163547

342.
Journal:	PLoS One. 2014 Sep 8;9(9):e107165.
Title:	EGFR-targeted TRAIL and a Smac mimetic synergize to overcome apoptosis resistance in KRAS mutant colorectal cancer cells.
Author:	Moller, Yvonne\|Siegemund, Martin\|Beyes, Sven\|Herr, Ricarda\|Lecis, Daniele\|Delia, Domenico\|Kontermann, Roland\|Brummer, Tilman\|Pfizenmaier, Klaus\|Olayioye, Monilola A
PMID:	25198428

343.
Journal:	Biochem Pharmacol. 2014 Dec 1;92(3):415-24.
Title:	Platinum(IV) complex LA-12 exerts higher ability than cisplatin to enhance TRAIL-induced cancer cell apoptosis via stimulation of mitochondrial pathway.
Author:	Jelinkova, Iva\|Safarikova, Barbora\|Vondalova Blanarova, Olga\|Skender, Belma\|Hofmanova, Jirina\|Sova, Petr\|Moyer, Mary Pat\|Kozubik, Alois\|Kolar, Zdenek\|Ehrmann, Jiri\|Hyrslova Vaculova, Alena
PMID:	25285768

344.
Journal:	Intest Res. 2014 Jan;12(1):34-41.
Title:	Parthenolide Sensitizes Human Colorectal Cancer Cells to Tumor Necrosis Factor-related Apoptosis-inducing Ligand through Mitochondrial and Caspase Dependent Pathway.
Author:	Trang, Kieu Thi Thu\|Kim, Se-Lim\|Park, Sang-Bae\|Seo, Seung-Young\|Choi, Chung-Hwan\|Park, Jin-Kyoung\|Moon, Jin-Chang\|Lee, Soo-Teik\|Kim, Sang-Wook
PMID:	25349561

345.
Journal:	Cell Death Dis. 2014 Dec 11;5:e1570.
Title:	XIAP-targeting drugs re-sensitize PIK3CA-mutated colorectal cancer cells for death receptor-induced apoptosis.
Author:	Ehrenschwender, M\|Bittner, S\|Seibold, K\|Wajant, H
PMID:	25501831

346.
Journal:	Oncogene. 2015 Feb 26;34(9):1150-9.
Title:	Functional characterization of the tumor-suppressor MARCKS in colorectal cancer and its association with survival.
Author:	Bickeboller, M\|Tagscherer, K E\|Kloor, M\|Jansen, L\|Chang-Claude, J\|Brenner, H\|Hoffmeister, M\|Toth, C\|Schirmacher, P\|Roth, W\|Blaker, H
PMID:	24662837

347.
Journal:	Target Oncol. 2015 Mar;10(1):65-76.
Title:	Anticancer activity of the type I insulin-like growth factor receptor antagonist, ganitumab, in combination with the death receptor 5 agonist, conatumumab.
Author:	Tabernero, Josep\|Chawla, Sant P\|Kindler, Hedy\|Reckamp, Karen\|Chiorean, E Gabriela\|Azad, Nilofer S\|Lockhart, A Craig\|Hsu, Cheng-Pang\|Baker, Nigel F\|Galimi, Francesco\|Beltran, Pedro\|Baselga, Jose
PMID:	24816908

348.
Journal:	Oncogene. 2015 May 21;34(21):2753-63.
Title:	The Gbeta5 protein regulates sensitivity to TRAIL-induced cell death in colon carcinoma.
Author:	Fuchs, D\|Metzig, M\|Bickeboller, M\|Brandel, C\|Roth, W
PMID:	25043307

349.
Journal:	Acta Biomater. 2015 Jan;12:174-182.
Title:	Hyaluronic acid-tumor necrosis factor-related apoptosis-inducing ligand conjugate for targeted treatment of liver fibrosis.
Author:	Yang, Jeong-A\|Kong, Won Ho\|Sung, Dong Kyung\|Kim, Hyemin\|Kim, Tae Hyung\|Lee, Kang Choon\|Hahn, Sei Kwang
PMID:	25305513

350.
Journal:	Int J Oncol. 2015 Feb;46(2):667-76.
Title:	The HMGB1 protein sensitizes colon carcinoma cells to cell death triggered by pro-apoptotic agents.
Author:	Zhang, Chengcheng Christine\|Gdynia, Georg\|Ehemann, Volker\|Roth, Wilfried
PMID:	25434832

351.
Journal:	Cell Signal. 2015 Feb;27(2):293-305.
Title:	HSP90 inhibitor NVP-AUY922 enhances TRAIL-induced apoptosis by suppressing the JAK2-STAT3-Mcl-1 signal transduction pathway in colorectal cancer cells.
Author:	Lee, Dae-Hee\|Sung, Ki Sa\|Bartlett, David L\|Kwon, Yong Tae\|Lee, Yong J
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352.
Journal:	Int J Oncol. 2015 Mar;46(3):1121-30.
Title:	Parthenolide enhances sensitivity of colorectal cancer cells to TRAIL by inducing death receptor 5 and promotes TRAIL-induced apoptosis.
Author:	Kim, Se-Lim\|Liu, Yu-Chuan\|Park, Young Ran\|Seo, Seung Young\|Kim, Seong Hun\|Kim, In Hee\|Lee, Seung Ok\|Lee, Soo Teik\|Kim, Dae-Ghon\|Kim, Sang-Wook
PMID:	25502339

353.
Journal:	Oncol Rep. 2015 Mar;33(3):1171-6.
Title:	Deferoxamine inhibits TRAIL-mediated apoptosis via regulation of autophagy in human colon cancer cells.
Author:	Moon, Ji-Hong\|Jeong, Jae-Kyo\|Park, Sang-Youel
PMID:	25524470

354.
Journal:	Cell Death Differ. 2015 Sep;22(9):1463-76.
Title:	USP11-dependent selective cIAP2 deubiquitylation and stabilization determine sensitivity to Smac mimetics.
Author:	Lee, E-W\|Seong, D\|Seo, J\|Jeong, M\|Lee, H-K\|Song, J
PMID:	25613375

355.
Journal:	Oncol Rep. 2015 Apr;33(4):1947-55.
Title:	Evaluation of preventive and therapeutic activity of novel non-steroidal anti-inflammatory drug, CG100649, in colon cancer: Increased expression of TNF-related apoptosis-inducing ligand receptors enhance the apoptotic response to combination treatment wit
Author:	Woo, Jong Kyu\|Kang, Ju-Hee\|Jang, Yeong-Su\|Ro, Seonggu\|Cho, Joong Myung\|Kim, Hwan-Mook\|Lee, Sang-Jin\|Oh, Seung Hyun
PMID:	25672292

356.
Journal:	J Pharmacol Sci. 2015 Jan;127(1):83-91.
Title:	TRAIL pathway is associated with inhibition of colon cancer by protopanaxadiol.
Author:	Zhang, Zhiyu\|Li, Zejuan\|Wu, Xiaohui\|Zhang, Chun-Feng\|Calway, Tyler\|He, Tong-Chuan\|Du, Wei\|Chen, Jianjun\|Wang, Chong-Zhi\|Yuan, Chun-Su
PMID:	25704023

357.
Journal:	Cancer Res. 2015 Apr 1;75(7):1423-32.
Title:	Small-Molecule ONC201/TIC10 Targets Chemotherapy-Resistant Colorectal Cancer Stem-like Cells in an Akt/Foxo3a/TRAIL-Dependent Manner.
Author:	Prabhu, Varun V\|Allen, Joshua E\|Dicker, David T\|El-Deiry, Wafik S
PMID:	25712124

358.
Journal:	Oncotarget. 2015 May 10;6(13):11614-26.
Title:	FTY720 enhances TRAIL-mediated apoptosis by up-regulating DR5 and down-regulating Mcl-1 in cancer cells.
Author:	Woo, Seon Min\|Seo, Bo Ram\|Min, Kyoung-jin\|Kwon, Taeg Kyu
PMID:	25843953

359.
Journal:	J Hematol Oncol. 2015 Mar 15;8:26.
Title:	Aloperine executes antitumor effects against multiple myeloma through dual apoptotic mechanisms.
Author:	Wang, He\|Yang, Shu\|Zhou, Hong\|Sun, Mingna\|Du, Lingran\|Wei, Minyan\|Luo, Meixia\|Huang, Jingzhu\|Deng, Hongzhu\|Feng, Yinghong\|Huang, Jun\|Zhou, Yi
PMID:	25886453

360.
Journal:	BMJ Open. 2015 May 11;5(5):e006840.
Title:	Evaluating holistic needs assessment in outpatient cancer care--a randomised controlled trial: the study protocol.
Author:	Snowden, Austyn\|Young, Jenny\|White, Craig\|Murray, Esther\|Richard, Claude\|Lussier, Marie-Therese\|MacArthur, Ewan\|Storey, Dawn\|Schipani, Stefano\|Wheatley, Duncan\|McMahon, Jeremy\|Ross, Elaine
PMID:	25967990

361.
Journal:	PLoS One. 2015 May 26;10(5):e0126526.
Title:	Death Receptor-Induced Apoptosis Signalling Regulation by Ezrin Is Cell Type Dependent and Occurs in a DISC-Independent Manner in Colon Cancer Cells.
Author:	Iessi, Elisabetta\|Zischler, Luciana\|Etringer, Aurelie\|Bergeret, Marion\|Morle, Aymeric\|Jacquemin, Guillaume\|Morizot, Alexandre\|Shirley, Sarah\|Lalaoui, Najoua\|Elifio-Esposito, Selene L\|Fais, Stefano\|Garrido, Carmen\|Solary, Eric\|Micheau, Olivier
PMID:	26010871

362.
Journal:	Tumour Biol. 2015 Nov;36(11):8819-29.
Title:	Shogaol overcomes TRAIL resistance in colon cancer cells via inhibiting of survivin.
Author:	Hwang, Jung Soon\|Lee, Hai-Chon\|Oh, Sang Cheul\|Lee, Dae-Hee\|Kwon, Ki Han
PMID:	26063410

363.
Journal:	Oxid Med Cell Longev. 2015;2015:154164.
Title:	Impact of Procyanidins from Different Berries on Caspase 8 Activation in Colon Cancer.
Author:	Minker, Carole\|Duban, Livine\|Karas, Daniel\|Jarvinen, Paivi\|Lobstein, Annelise\|Muller, Christian D
PMID:	26180579

364.
Journal:	Protein Pept Lett. 2015;22(11):1000-6.
Title:	Fused hydrophobic elastin-like-peptides (ELP) enhance biological activity of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL).
Author:	Huang, Kaizong\|Duan, Ningjun\|Zou, Wenyan\|Zhang, Chunmei\|Lai, Yueyang\|Shen, Pingping\|Hua, Zichun
PMID:	26299999

365.
Journal:	Oncotarget. 2015 Sep 22;6(28):25828-42.
Title:	Understanding of tolerance in TRAIL-induced apoptosis and cancelation of its machinery by alpha-mangostin, a xanthone derivative.
Author:	Kumazaki, Minami\|Shinohara, Haruka\|Taniguchi, Kohei\|Ueda, Hiroshi\|Nishi, Mayuko\|Ryo, Akihide\|Akao, Yukihiro
PMID:	26304927

366.
Journal:	Genom Data. 2015 Sep 1;5:189-191.
Title:	Epigenetic Regulation of Apoptosis and Cell Cycle Regulatory Genes in Human Colon Carcinoma Cells.
Author:	Paschall, Amy V\|Liu, Kebin
PMID:	26309812

367.
Journal:	Biomaterials. 2015 Dec;71:84-99.
Title:	LNA aptamer based multi-modal, Fe3O4-saturated lactoferrin (Fe3O4-bLf) nanocarriers for triple positive (EpCAM, CD133, CD44) colon tumor targeting and NIR, MRI and CT imaging.
Author:	Roy, Kislay\|Kanwar, Rupinder K\|Kanwar, Jagat R
PMID:	26318819

368.
Journal:	BMC Cancer. 2015 Sep 15;15:638.
Title:	Coronin 2A (CRN5) expression is associated with colorectal adenoma-adenocarcinoma sequence and oncogenic signalling.
Author:	Rastetter, Raphael H\|Blomacher, Margit\|Drebber, Uta\|Marko, Marija\|Behrens, Juliane\|Solga, Roxana\|Hojeili, Sarah\|Bhattacharya, Kurchi\|Wunderlich, Claudia M\|Wunderlich, F Thomas\|Odenthal, Margarete\|Ziemann, Anja\|Eichinger, Ludwig\|Clemen, Christoph S
PMID:	26373535

369.
Journal:	J Control Release. 2015 Dec 28;220(Pt B):671-81.
Title:	Delivery of tumor-homing TRAIL sensitizer with long-acting TRAIL as a therapy for TRAIL-resistant tumors.
Author:	Oh, Yumin\|Swierczewska, Magdalena\|Kim, Tae Hyung\|Lim, Sung Mook\|Eom, Ha Na\|Park, Jae Hyung\|Na, Dong Hee\|Kim, Kwangmeyung\|Lee, Kang Choon\|Pomper, Martin G\|Lee, Seulki
PMID:	26381901

370.
Journal:	Int J Oncol. 2015 Dec;47(6):2188-96.
Title:	Goniothalamin enhances TRAIL-induced apoptosis in colorectal cancer cells through DR5 upregulation and cFLIP downregulation.
Author:	Sophonnithiprasert, Thanet\|Nilwarangkoon, Sirinun\|Nakamura, Yukio\|Watanapokasin, Ramida
PMID:	26499766

371.
Journal:	Cell Mol Biol (Noisy-le-grand). 2015 Oct 30;61(6):108-12.
Title:	Genetic variants in the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and death receptor (DR4) genes contribute to susceptibility to colorectal cancer in pakistani population.
Author:	Zahoor, A\|Mansoor, Q\|Farooqi, A A\|Fayyaz, S\|Naz, G\|Ismail, M
PMID:	26518902

372.
Journal:	Cell Mol Biol (Noisy-le-grand). 2015 Oct 30;61(6):1.
Title:	Editorial.
Author:	Farooqi, A A\|Ismail, M
PMID:	26520390

373.
Journal:	Yao Xue Xue Bao. 2015 Oct;50(10):1252-7.
Title:	[Sensitization of human colon cancer HT-29 cells to TRAIL-induced apoptosis by gambognic acid].
Author:	Ye, Ji-lin\|Yu, You-jiang\|Wu, Ai-lian\|Wang, Dong-yan\|Liu, Yong-chun\|Liu, Yan-qing
PMID:	26837170

374.
Journal:	Oncogene. 2016 Jan 14;35(2):148-57.
Title:	mTOR inhibitors induce apoptosis in colon cancer cells via CHOP-dependent DR5 induction on 4E-BP1 dephosphorylation.
Author:	He, K\|Zheng, X\|Li, M\|Zhang, L\|Yu, J
PMID:	25867072

375.
Journal:	J Cell Biochem. 2016 May;117(5):1078-91.
Title:	TRAIL-Induced Caspase Activation Is a Prerequisite for Activation of the Endoplasmic Reticulum Stress-Induced Signal Transduction Pathways.
Author:	Lee, Dae-Hee\|Sung, Ki Sa\|Guo, Zong Sheng\|Kwon, William Taehyung\|Bartlett, David L\|Oh, Sang Cheul\|Kwon, Yong Tae\|Lee, Yong J
PMID:	26212606

376.
Journal:	Drug Deliv. 2016 Jun;23(5):1773-87.
Title:	Oxaliplatin immuno hybrid nanoparticles for active targeting: an approach for enhanced apoptotic activity and drug delivery to colorectal tumors.
Author:	Tummala, Shashank\|Gowthamarajan, K\|Satish Kumar, M N\|Wadhwani, Ashish
PMID:	26377238

377.
Journal:	Oncotarget. 2016 Jan 26;7(4):4356-68.
Title:	Niacin alleviates TRAIL-mediated colon cancer cell death via autophagy flux activation.
Author:	Kim, Sung-Wook\|Lee, Ju-Hee\|Moon, Ji-Hong\|Nazim, Uddin M D\|Lee, You-Jin\|Seol, Jae-Won\|Hur, Jin\|Eo, Seong-Kug\|Lee, John-Hwa\|Park, Sang-Youel
PMID:	26517672

378.
Journal:	Pharm Res. 2016 Mar;33(3):615-26.
Title:	Doxorubicin-Bound Albumin Nanoparticles Containing a TRAIL Protein for Targeted Treatment of Colon Cancer.
Author:	Thao, Le Quang\|Byeon, Hyeong Jun\|Lee, Changkyu\|Lee, Seunghyun\|Lee, Eun Seong\|Choi, Yeon Woong\|Choi, Han-Gon\|Park, Eun-Seok\|Lee, Kang Choon\|Youn, Yu Seok
PMID:	26526555

379.
Journal:	Artif Cells Nanomed Biotechnol. 2016 Dec;44(8):1835-1850.
Title:	Formulation and optimization of oxaliplatin immuno-nanoparticles using Box-Behnken design and cytotoxicity assessment for synergistic and receptor-mediated targeting in the treatment of colorectal cancer.
Author:	Tummala, Shashank\|Gowthamarajan, K\|Satish Kumar, M N\|Praveen, T K\|Yamjala, Karthik\|Tripuraneni, Naga Srinivas\|Prakash, Ashwati
PMID:	26697734

380.
Journal:	J Biol Chem. 2016 Mar 11;291(11):5960-70.
Title:	The Deubiquitinase Inhibitor PR-619 Sensitizes Normal Human Fibroblasts to Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)-mediated Cell Death.
Author:	Crowder, Roslyn N\|Dicker, David T\|El-Deiry, Wafik S
PMID:	26757822

381.
Journal:	Oncotarget. 2016 Feb 9;7(6):7161-78.
Title:	The probiotic Propionibacterium freudenreichii as a new adjuvant for TRAIL-based therapy in colorectal cancer.
Author:	Cousin, Fabien J\|Jouan-Lanhouet, Sandrine\|Theret, Nathalie\|Brenner, Catherine\|Jouan, Elodie\|Le Moigne-Muller, Gwenaelle\|Dimanche-Boitrel, Marie-Therese\|Jan, Gwenael
PMID:	26771233

382.
Journal:	Oncotarget. 2016 Jan 26;7(4):3709-25.
Title:	Cooperative TRAIL production mediates IFNalpha/Smac mimetic-induced cell death in TNFalpha-resistant solid cancer cells.
Author:	Roesler, Stefanie\|Eckhardt, Ines\|Wolf, Sebastian\|Fulda, Simone
PMID:	26788912

383.
Journal:	PLoS One. 2016 Feb 5;11(2):e0147960.
Title:	Lactobacillus casei Exerts Anti-Proliferative Effects Accompanied by Apoptotic Cell Death and Up-Regulation of TRAIL in Colon Carcinoma Cells.
Author:	Tiptiri-Kourpeti, Angeliki\|Spyridopoulou, Katerina\|Santarmaki, Valentina\|Aindelis, Georgios\|Tompoulidou, Evgenia\|Lamprianidou, Eleftheria E\|Saxami, Georgia\|Ypsilantis, Petros\|Lampri, Evangeli S\|Simopoulos, Constantinos\|Kotsianidis, Ioannis\|Galanis, Alex\|K
PMID:	26849051

384.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2016 Mar;19(3):260-1.
Title:	[Key points and difficulties in implementing enhanced recovery after surgery of colorectal cancer].
Author:	Kong, Xiangxing\|Li, Jun\|Ding, Kefeng
PMID:	27003642

385.
Journal:	Biochem Biophys Res Commun. 2016 Apr 29;473(2):586-92.
Title:	Bakuchiol sensitizes cancer cells to TRAIL through ROS- and JNK-mediated upregulation of death receptors and downregulation of survival proteins.
Author:	Park, Mi Hee\|Kim, Jong Han\|Chung, Young-Ho\|Lee, Seung Ho
PMID:	27033605

386.
Journal:	J Biol Chem. 2016 May 27;291(22):11843-51.
Title:	Cleavage by Caspase 8 and Mitochondrial Membrane Association Activate the BH3-only Protein Bid during TRAIL-induced Apoptosis.
Author:	Huang, Kai\|Zhang, Jingjing\|O'Neill, Katelyn L\|Gurumurthy, Channabasavaiah B\|Quadros, Rolen M\|Tu, Yaping\|Luo, Xu
PMID:	27053107

387.
Journal:	Oncotarget. 2016 Jul 5;7(27):41488-41504.
Title:	Hypoxia regulates TRAIL sensitivity of colorectal cancer cells through mitochondrial autophagy.
Author:	Knoll, Gertrud\|Bittner, Sebastian\|Kurz, Maria\|Jantsch, Jonathan\|Ehrenschwender, Martin
PMID:	27166192

388.
Journal:	Mol Cancer Ther. 2016 Jul;15(7):1591-601.
Title:	Secretory TRAIL-Armed Natural Killer Cell-Based Therapy: In Vitro and In Vivo Colorectal Peritoneal Carcinomatosis Xenograft.
Author:	Song, Xinxin\|Hong, Se-Hoon\|Kwon, William T\|Bailey, Lisa M\|Basse, Per\|Bartlett, David L\|Kwon, Yong Tae\|Lee, Yong J
PMID:	27196776

389.
Journal:	Apoptosis. 2016 Oct;21(10):1144-57.
Title:	Clitocine potentiates TRAIL-mediated apoptosis in human colon cancer cells by promoting Mcl-1 degradation.
Author:	Sun, Jian-Guo\|Ruan, Feng\|Zeng, Xue-Li\|Xiang, Jun\|Li, Xia\|Wu, Ping\|Fung, Kwok Pui\|Liu, Fei-Yan
PMID:	27421828

390.
Journal:	Exp Cell Res. 2016 Sep 10;347(1):133-42.
Title:	Perturbation of the Warburg effect increases the sensitivity of cancer cells to TRAIL-induced cell death.
Author:	Kumazaki, Minami\|Shinohara, Haruka\|Taniguchi, Kohei\|Takai, Tomoaki\|Kuranaga, Yuki\|Sugito, Nobuhiko\|Akao, Yukihiro
PMID:	27453209

391.
Journal:	J Biol Chem. 2016 Aug 5;291(32):16923.
Title:	Gossypol induces death receptor-5 through activation of ROS-ERK-CHOP pathway and sensitizes colon cancer cells to TRAIL.
Author:	Sung, Bokyung\|Ravindran, Jayaraj\|Prasad, Sahdeo\|Pandey, Manoj K\|Aggarwal, Bharat B
PMID:	27496964

392.
Journal:	J Biol Chem. 2016 Aug 5;291(32):16925.
Title:	Nimbolide sensitizes human colon cancer cells to TRAIL through reactive oxygen species- and ERK-dependent up-regulation of death receptors, p53, and Bax.
Author:	Gupta, Subash C\|Reuter, Simone\|Phromnoi, Kanokkarn\|Park, Byoungduck\|Hema, Padmanabhan S\|Nair, Mangalam\|Aggarwal, Bharat B
PMID:	27496966

393.
Journal:	Cell Death Dis. 2016 Aug 11;7(8):e2334.
Title:	Ginsenoside compound K sensitizes human colon cancer cells to TRAIL-induced apoptosis via autophagy-dependent and -independent DR5 upregulation.
Author:	Chen, Lei\|Meng, Yue\|Sun, Qi\|Zhang, Zhongyu\|Guo, Xiaoqing\|Sheng, Xiaotong\|Tai, Guihua\|Cheng, Hairong\|Zhou, Yifa
PMID:	27512955

394.
Journal:	Oncotarget. 2016 Sep 13;7(37):59503-59518.
Title:	Metformin enhances TRAIL-induced apoptosis by Mcl-1 degradation via Mule in colorectal cancer cells.
Author:	Park, Seong Hye\|Lee, Dae-Hee\|Kim, Jung Lim\|Kim, Bo Ram\|Na, Yoo Jin\|Jo, Min Jee\|Jeong, Yoon A\|Lee, Suk-Young\|Lee, Sun Il\|Lee, Yong Yook\|Oh, Sang Cheul
PMID:	27517746

395.
Journal:	BMC Cancer. 2016 Aug 12;16:624.
Title:	IAP antagonists Birinapant and AT-406 efficiently synergise with either TRAIL, BRAF, or BCL-2 inhibitors to sensitise BRAFV600E colorectal tumour cells to apoptosis.
Author:	Perimenis, Philippos\|Galaris, Apostolos\|Voulgari, Alexandra\|Prassa, Margarita\|Pintzas, Alexander
PMID:	27520705

396.
Journal:	Biochem Biophys Res Commun. 2016 Sep 30;478(4):1515-20.
Title:	mTOR inhibition sensitizes ONC201-induced anti-colorectal cancer cell activity.
Author:	Jin, Zhe-Zhu\|Wang, Wei\|Fang, Di-Long\|Jin, Yong-Jun
PMID:	27565731

397.
Journal:	Oncotarget. 2016 Oct 4;7(40):65957-65967.
Title:	Inhibition of never in mitosis A (NIMA)-related kinase-4 reduces survivin expression and sensitizes cancer cells to TRAIL-induced cell death.
Author:	Park, So Jung\|Jo, Doo Sin\|Jo, Se-Young\|Shin, Dong Woon\|Shim, Sangmi\|Jo, Yoon Kyung\|Shin, Ji Hyun\|Ha, Ye Jin\|Jeong, Seong-Yun\|Hwang, Jung Jin\|Kim, Young Sam\|Suh, Young-Ah\|Chang, Jong Wook\|Kim, Jin Cheon\|Cho, Dong-Hyung
PMID:	27602754

398.
Journal:	PLoS One. 2016 Sep 12;11(9):e0162700.
Title:	Probe-Based Confocal Laser Endomicroscopy for Imaging TRAIL-Expressing Mesenchymal Stem Cells to Monitor Colon Xenograft Tumors In Vivo.
Author:	Zhang, Zhen\|Li, Ming\|Chen, Feixue\|Li, Lixiang\|Liu, Jun\|Li, Zhen\|Ji, Rui\|Zuo, Xiuli\|Li, Yanqing
PMID:	27617958

399.
Journal:	Apoptosis. 2016 Nov;21(11):1291-1301.
Title:	Gefitinib enhances human colon cancer cells to TRAIL-induced apoptosis of via autophagy- and JNK-mediated death receptors upregulation.
Author:	Chen, Lei\|Meng, Yue\|Guo, Xiaoqing\|Sheng, Xiaotong\|Tai, Guihua\|Zhang, Fenglei\|Cheng, Hairong\|Zhou, Yifa
PMID:	27629794

400.
Journal:	Cell Death Discov. 2016 Sep 12;2:16067.
Title:	Targeting the metabolic pathway of human colon cancer overcomes resistance to TRAIL-induced apoptosis.
Author:	Carr, Ryan M\|Qiao, Guilin\|Qin, Jianzhong\|Jayaraman, Sundararajan\|Prabhakar, Bellur S\|Maker, Ajay V
PMID:	27648301

401.
Journal:	Inflamm Bowel Dis. 2016 Nov;22(11):2593-2606.
Title:	Colonic Lamina Propria Inflammatory Cells from Patients with IBD Induce the Nuclear Factor-E2 Related Factor-2 Thereby Leading to Greater Proteasome Activity and Apoptosis Protection in Human Colonocytes.
Author:	Kruse, Marie-Luise\|Friedrich, Martin\|Arlt, Alexander\|Rocken, Christoph\|Egberts, Jan-Hendrik\|Sebens, Susanne\|Schafer, Heiner
PMID:	27661668

402.
Journal:	Cancer Lett. 2016 Dec 28;383(2):145-153.
Title:	BAY61-3606 potentiates the anti-tumor effects of TRAIL against colon cancer through up-regulating DR4 and down-regulating NF-kappaB.
Author:	Du, Jipei\|Wang, Yufang\|Chen, Degao\|Ji, Guangyu\|Ma, Qizhao\|Liao, Shiping\|Zheng, Yanjiang\|Zhang, Ji\|Hou, Yiping
PMID:	27721019

403.
Journal:	Cancer Lett. 2016 Dec 28;383(2):250-260.
Title:	High-order TRAIL oligomer formation in TRAIL-coated lipid nanoparticles enhances DR5 cross-linking and increases antitumour effect against colon cancer.
Author:	De Miguel, Diego\|Gallego-Lleyda, Ana\|Ayuso, Jose Maria\|Pejenaute-Ochoa, Dolores\|Jarauta, Vidal\|Marzo, Isabel\|Fernandez, Luis J\|Ochoa, Ignacio\|Conde, Blanca\|Anel, Alberto\|Martinez-Lostao, Luis
PMID:	27725224

404.
Journal:	J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Nov 15;1036-1037:142-148.
Title:	An HPLC method associated with a thermodynamic analysis to compare the binding of TRAIL and its nanovectorized form to death receptors DR4 and DR5 and their relationship to cytotoxicity.
Author:	Guillaume, Yves Claude\|Lethier, Lydie\|Andre, Claire
PMID:	27750195

405.
Journal:	Sci Rep. 2016 Nov 9;6:36532.
Title:	Death receptor 5 (DR5) and a 5-gene apoptotic biomarker panel with significant differential diagnostic potential in colorectal cancer.
Author:	Devetzi, Marina\|Kosmidou, Vivian\|Vlassi, Margarita\|Perysinakis, Iraklis\|Aggeli, Chrysanthi\|Choreftaki, Theodosia\|Zografos, Georgios N\|Pintzas, Alexander
PMID:	27827395

406.
Journal:	Technology (Singap World Sci). 2016 Mar;4(1):60-69.
Title:	Two-stage nanoparticle delivery of piperlongumine and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) anti-cancer therapy.
Author:	Sharkey, Charles C\|Li, Jiahe\|Roy, Sweta\|Wu, Qianhui\|King, Michael R
PMID:	27853735

407.
Journal:	Artif Cells Nanomed Biotechnol. 2017 Mar;45(2):261-269.
Title:	Oxaliplatin immunohybrid nanoparticles in vitro synergistic suppression evaluation in treatment of colorectal cancer.
Author:	Tummala, Shashank\|Gowthamarajan, K\|Satish Kumar, M N
PMID:	26933919

408.
Journal:	Anticancer Drugs. 2017 Jan;28(1):66-74.
Title:	Tunicamycin enhances human colon cancer cells to TRAIL-induced apoptosis by JNK-CHOP-mediated DR5 upregulation and the inhibition of the EGFR pathway.
Author:	Guo, Xiaoqing\|Meng, Yue\|Sheng, Xiaotong\|Guan, Yuan\|Zhang, Fenglei\|Han, Zhen\|Kang, Yuying\|Tai, Guihua\|Zhou, Yifa\|Cheng, Hairong
PMID:	27603596

409.
Journal:	Oncol Rep. 2017 Jan;37(1):571-578.
Title:	miR-20a-directed regulation of BID is associated with the TRAIL sensitivity in colorectal cancer.
Author:	Huang, Guanli\|Chen, Xiangjian\|Cai, Yefeng\|Wang, Xiaobo\|Xing, Chungen
PMID:	28004114

410.
Journal:	Oncotarget. 2017 Jul 11;8(28):45213-45223.
Title:	Knockdown of miR-27a sensitizes colorectal cancer stem cells to TRAIL by promoting the formation of Apaf-1-caspase-9 complex.
Author:	Zhang, Rui\|Xu, Jian\|Zhao, Jian\|Bai, Jinghui
PMID:	28423356

411.
Journal:	Cell Cycle. 2017 Jun 18;16(12):1193-1200.
Title:	The CDK4/6 inhibitor palbociclib synergizes with irinotecan to promote colorectal cancer cell death under hypoxia.
Author:	Zhang, Jun\|Zhou, Lanlan\|Zhao, Shuai\|Dicker, David T\|El-Deiry, Wafik S
PMID:	28486050

412.
Journal:	Int J Mol Sci. 2017 Jun 6;18(6). pii: ijms18061211.
Title:	Novel Structurally Related Flavones Augment Cell Death Induced by rhsTRAIL.
Author:	Bronikowska, Joanna\|Szliszka, Ewelina\|Kostrzewa-Suslow, Edyta\|Jaworska, Dagmara\|Czuba, Zenon P\|Bednarski, Piotr\|Krol, Wojciech
PMID:	28587286

413.
Journal:	Arch Esp Urol. 2017 Jun;70(5):503-512.
Title:	[Comparison of two on-line risk calculators versus the detection of circulating prostate cells for the detection of high risk prostate cancer at first biopsy.]
Author:	Murray, Nigel P\|Fuentealba, Cynthia\|Reyes, Eduardo\|Jacob, Omar
PMID:	28613202

414.
Journal:	PLoS One. 2017 Jul 7;12(7):e0180834.
Title:	MDR1A deficiency restrains tumor growth in murine colitis-associated carcinogenesis.
Author:	Hennenberg, Eva Maria\|Eyking, Annette\|Reis, Henning\|Cario, Elke
PMID:	28686677

415.
Journal:	Theranostics. 2017 Jun 1;7(8):2261-2276.
Title:	Targeted Delivery to Tumor-associated Pericytes via an Affibody with High Affinity for PDGFRbeta Enhances the in vivo Antitumor Effects of Human TRAIL.
Author:	Tao, Ze\|Yang, Hao\|Shi, Qiuxiao\|Fan, Qing\|Wan, Lin\|Lu, Xiaofeng
PMID:	28740549

416.
Journal:	PLoS One. 2017 Aug 2;12(8):e0180541.
Title:	Cancer stem cell-related gene expression as a potential biomarker of response for first-in-class imipridone ONC201 in solid tumors.
Author:	Prabhu, Varun V\|Lulla, Amriti R\|Madhukar, Neel S\|Ralff, Marie D\|Zhao, Dan\|Kline, Christina Leah B\|Van den Heuvel, A Pieter J\|Lev, Avital\|Garnett, Mathew J\|McDermott, Ultan\|Benes, Cyril H\|Batchelor, Tracy T\|Chi, Andrew S\|Elemento, Olivier\|Allen, Joshua E\|E
PMID:	28767654

417.
Journal:	Cell Oncol (Dordr). 2017 Dec;40(6):593-607.
Title:	TRAIL enhances quinacrine-mediated apoptosis in breast cancer cells through induction of autophagy via modulation of p21 and DR5 interactions.
Author:	Das, Sarita\|Nayak, Anmada\|Siddharth, Sumit\|Nayak, Deepika\|Narayan, Satya\|Kundu, Chanakya Nath
PMID:	28936683

418.
Journal:	Drug Deliv. 2017 Nov;24(1):1526-1536.
Title:	TRAIL and curcumin codelivery nanoparticles enhance TRAIL-induced apoptosis through upregulation of death receptors.
Author:	Yang, Xi\|Li, Zhaojun\|Wu, Qinjie\|Chen, Shouchun\|Yi, Cheng\|Gong, Changyang
PMID:	28994313

419.
Journal:	Mol Med Rep. 2017 Dec;16(6):9607-9612.
Title:	TRAIL mutant membrane penetrating peptide alike (TMPPA) TRAILMu3 enhances the antitumor effects of TRAIL in vitro and in vivo.
Author:	Zhu, Hong\|Yan, Juan\|Xu, Qi\|Wei, Lijia\|Huang, Xianzhou\|Chen, Shouchun\|Yi, Cheng
PMID:	29039511

420.
Journal:	Mol Med Rep. 2017 Dec;16(6):9375-9382.
Title:	Combination of oncolytic adenovirus and luteolin exerts synergistic antitumor effects in colorectal cancer cells and a mouse model.
Author:	Xiao, Boduan\|Qin, Yun\|Ying, Chang\|Ma, Buyun\|Wang, Binrong\|Long, Fei\|Wang, Ruwei\|Fang, Ling\|Wang, Yigang
PMID:	29039580

421.
Journal:	Oncol Rep. 2017 Dec;38(6):3439-3446.
Title:	Synergism between alpha-mangostin and TRAIL induces apoptosis in squamous cell carcinoma of the oral cavity through the mitochondrial pathway.
Author:	Fukuda, Masakatsu\|Sakashita, Hide\|Hayashi, Hiroyasu\|Shiono, Junya\|Miyake, Genki\|Komine, Yusuke\|Taira, Fuyoko\|Sakashita, Hideaki
PMID:	29039600

422.
Journal:	Oncotarget. 2017 Jul 28;8(47):82593-82608.
Title:	N-myc downstream-regulated gene 1 promotes apoptosis in colorectal cancer via up-regulating death receptor 4.
Author:	Zhang, Xian\|Feng, Bo\|Zhu, Fan\|Yu, Chaoran\|Lu, Jiaoyang\|Pan, Meng\|He, Zirui\|Wangpu, Xiongzhi\|Sun, Jing\|Yang, Xiao
PMID:	29137287

423.
Journal:	Oncotarget. 2017 Aug 24;8(53):91258-91269.
Title:	A small molecule, (E)-2-methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) phenol suppresses tumor growth via inhibition of IkappaB kinase beta in colorectal cancer in vivo and in vitro.
Author:	Zheng, Jie\|Park, Mi Hee\|Lee, Hee Pom\|Hyun, Byung Kook\|Chun, Hyung Ok\|Jung, Sung Hee\|Seo, Hyun Ok\|Ham, Young Wan\|Han, Sang-Bae\|Hong, Jin Tae
PMID:	29207641

424.
Journal:	Am J Transl Res. 2017 Nov 15;9(11):4945-4953. eCollection 2017.
Title:	Hsp90 inhibitor sensitizes TRAIL-mediated apoptosis via chop-dependent DR5 upregulation in colon cancer cells.
Author:	Yao, Zhicheng\|Chen, Ang\|Li, Xin\|Zhu, Zhiyong\|Jiang, Xin
PMID:	29218092

425.
Journal:	Oncotarget. 2017 Dec 8;8(70):115164-115178.
Title:	Molecular crosstalk between ferroptosis and apoptosis: emerging role of ER stress-induced p53-independent PUMA expression.
Author:	Hong, Se Hoon\|Lee, Dae-Hee\|Lee, Young-Sun\|Jo, Min Jee\|Jeong, Yoon A\|Kwon, William T\|Choudry, Haroon A\|Bartlett, David L\|Lee, Yong J
PMID:	29383150

426.
Journal:	Oncogene. 2018 Jan 4;37(1):39-51.
Title:	Nuclear factor E2-related factor-2 has a differential impact on MCT1 and MCT4 lactate carrier expression in colonic epithelial cells: a condition favoring metabolic symbiosis between colorectal cancer and stromal cells.
Author:	Diehl, K\|Dinges, L-A\|Helm, O\|Ammar, N\|Plundrich, D\|Arlt, A\|Rocken, C\|Sebens, S\|Schafer, H
PMID:	28846107

427.
Journal:	Colloids Surf B Biointerfaces. 2018 Jan 1;161:339-346.
Title:	Improving sensitivity of magnetic resonance imaging by using a dual-targeted magnetic iron oxide nanoprobe.
Author:	Chen, Ling\|Xie, Jun\|Wu, Haoan\|Zang, Fengchao\|Ma, Ming\|Hua, Zichun\|Gu, Ning\|Zhang, Yu
PMID:	29100127

428.
Journal:	J Exp Clin Cancer Res. 2018 Jan 22;37(1):11.
Title:	Anti-tumor effects of ONC201 in combination with VEGF-inhibitors significantly impacts colorectal cancer growth and survival in vivo through complementary non-overlapping mechanisms.
Author:	Wagner, Jessica\|Kline, C Leah\|Zhou, Lanlan\|Khazak, Vladimir\|El-Deiry, Wafik S
PMID:	29357916

429.
Journal:	BMC Health Serv Res. 2018 Jan 29;18(1):49.
Title:	Validity of the CR-POSSUM model in surgery for colorectal cancer in Spain (CCR-CARESS study) and comparison with other models to predict operative mortality.
Author:	Bare, Marisa\|Alcantara, Manuel Jesus\|Gil, Maria Jose\|Collera, Pablo\|Pont, Marina\|Escobar, Antonio\|Sarasqueta, Cristina\|Redondo, Maximino\|Briones, Eduardo\|Dujovne, Paula\|Quintana, Jose Maria
PMID:	29378647

430.
Journal:	Cell Physiol Biochem. 2018;45(2):605-613.
Title:	Correlation Between Baseline Osteoprotegerin Serum Levels and Prognosis of Advanced-Stage Colorectal Cancer Patients.
Author:	De Toni, Enrico N\|Nagel, Dorothea\|Philipp, Alexander B\|Herbst, Andreas\|Thalhammer, Isabel\|Mayerle, Julia\|Torok, Helga-Paula\|Brandl, Lydia\|Kolligs, Frank T
PMID:	29402836

431.
Journal:	Oncotarget. 2018 Jan 31;9(13):11322-11335.
Title:	Targeting scFv-Fc-scTRAIL fusion proteins to tumor cells.
Author:	Hutt, Meike\|Fellermeier-Kopf, Sina\|Seifert, Oliver\|Schmitt, Lisa C\|Pfizenmaier, Klaus\|Kontermann, Roland E
PMID:	29541416

432.
Journal:	Oncotarget. 2018 Feb 17;9(21):15566-15578.
Title:	Relationship between the agonist activity of synthetic ligands of TRAIL-R2 and their cell surface binding modes.
Author:	Chekkat, Neila\|Lombardo, Caterina M\|Seguin, Cendrine\|Lechner, Marie-Charlotte\|Dufour, Florent\|Nomine, Yves\|De Giorgi, Marcella\|Frisch, Benoit\|Micheau, Olivier\|Guichard, Gilles\|Altschuh, Daniele\|Fournel, Sylvie
PMID:	29643993

433.
Journal:	Med Sci Monit. 2018 Apr 26;24:2550-2561.
Title:	Effects of Recombinant Circularly Permuted Tumor Necrosis Factor (TNF)-Related Apoptosis-Inducing Ligand (TRAIL) (Recombinant Mutant Human TRAIL) in Combination with 5-Fluorouracil in Human Colorectal Cancer Cell Lines HCT116 and SW480.
Author:	Sun, Tongyou\|Zhu, Tienian\|Liang, Xiujun\|Yang, Shifang\|Zhao, Ruijing
PMID:	29695684

434.
Journal:	Pathol Res Pract. 2018 Jun;214(6):826-834.
Title:	Comprehensive expression analysis of TNF-related apoptosis-inducing ligand and its receptors in colorectal cancer: Correlation with MAPK alterations and clinicopathological associations.
Author:	Tsikalakis, Spyridon\|Chatziandreou, Ilenia\|Michalopoulos, Nikolaos V\|Theodoropoulos, Georgios E\|Sakellariou, Stratigoula\|Korkolopoulou, Penelope\|Patsouris, Efstratios\|Saetta, Angelica A
PMID:	29731264

435.
Journal:	Cancer Commun (Lond). 2018 Jul 3;38(1):43.
Title:	Azithromycin enhances anticancer activity of TRAIL by inhibiting autophagy and up-regulating the protein levels of DR4/5 in colon cancer cells in vitro and in vivo.
Author:	Qiao, Xinran\|Wang, Xiaofei\|Shang, Yue\|Li, Yi\|Chen, Shu-Zhen
PMID:	29970185

436.
Journal:	Artif Cells Nanomed Biotechnol. 2018 Aug 10:1-11.
Title:	Modified PAMAM vehicles for effective TRAIL gene delivery to colon adenocarcinoma: in vitro and in vivo evaluation.
Author:	Pishavar, Elham\|Attaranzadeh, Armin\|Alibolandi, Mona\|Ramezani, Mohammad\|Hashemi, Maryam
PMID:	30095012

437.
Journal:	J Cell Biochem. 2018 Aug 30.
Title:	Ferroptosis-inducing agents enhance TRAIL-induced apoptosis through upregulation of death receptor 5.
Author:	Lee, Young-Sun\|Lee, Dae-Hee\|Jeong, So Yeon\|Park, Seong Hye\|Oh, Sang Cheul\|Park, Yong Seok\|Yu, Jian\|Choudry, Haroon A\|Bartlett, David L\|Lee, Yong J
PMID:	30160785

438.
Journal:	Cancer Res. 2018 Sep 1;78(17):5183.
Title:	Editor's Note: Zerumbone Enhances TRAIL-Induced Apoptosis through the Induction of Death Receptors in Human Colon Cancer Cells: Evidence for an Essential Role of Reactive Oxygen Species.
Author:
PMID:	30181307

439.
Journal:	Int J Oncol. 2018 Sep 14.
Title:	Lipocalin 2 inversely regulates TRAIL sensitivity through p38 MAPK-mediated DR5 regulation in colorectal cancer.
Author:	Kim, Se-Lim\|Min, In Suk\|Park, Young Ran\|Lee, Soo Teik\|Kim, Sang-Wook
PMID:	30221676

440.
Journal:	Cell Physiol Biochem. 2018 Sep 26;49(6):2151-2162.
Title:	miR-128 Targets the SIRT1/ROS/DR5 Pathway to Sensitize Colorectal Cancer to TRAIL-Induced Apoptosis.
Author:	Lian, Bo\|Yang, Dongxiang\|Liu, Yanlong\|Shi, Gang\|Li, Jibin\|Yan, Xiaofei\|Jin, Keer\|Liu, Xin\|Zhao, Jianfeng\|Shang, Wen\|Zhang, Rui
PMID:	30257253

441.
Journal:	Gastroenterology. 2018 Sep 26. pii: S0016-5085(18)35036-4.
Title:	Intestinal Inflammation and Dysregulated Immunity in Patients with Inherited Caspase-8 Deficiency.
Author:	Lehle, Anna S\|Farin, Henner F\|Marquardt, Benjamin\|Michels, Birgitta E\|Magg, Thomas\|Li, Yue\|Liu, Yanshan\|Ghalandary, Maryam\|Lammens, Katja\|Hollizeck, Sebastian\|Rohlfs, Meino\|Hauck, Fabian\|Conca, Raffaele\|Walz, Christoph\|Weiss, Batia\|Lev, Atar\|Simon, Amos J
PMID:	30267714

442.
Journal:	Br J Cancer. 2018 Oct;119(8):971-977.
Title:	Colon-specific eQTL analysis to inform on functional SNPs.
Author:	Moreno, Victor\|Alonso, M Henar\|Closa, Adria\|Valles, Xavier\|Diez-Villanueva, Anna\|Valle, Laura\|Castellvi-Bel, Sergi\|Sanz-Pamplona, Rebeca\|Lopez-Doriga, Adriana\|Cordero, David\|Sole, Xavier
PMID:	30283144

443.
Journal:	Cancer Biol Ther. 2018 Oct 25:1-11.
Title:	Ixazomib promotes CHOP-dependent DR5 induction and apoptosis in colorectal cancer cells.
Author:	Yue, Dan\|Sun, Xun
PMID:	30359552