Primary Site >> Colorectal Cancer

Gene >> TNFRSF10B

Journal: Am Surg. 1980 Feb;46(2):105-7.
Title: Frontiers in carcinoma of the colorectum from carcinogenesis to adjuvant therapy.
Author: Humphrey, L J
PMID: 7369627
Journal: J Natl Cancer Inst. 1985 Jul;75(1):67-75.
Title: Lymphokine-activated killer (LAK) cell phenomenon. IV. Lysis by LAK cell clones of fresh human tumor cells from autologous and multiple allogeneic tumors.
Author: Rayner, A A|Grimm, E A|Lotze, M T|Wilson, D J|Rosenberg, S A
PMID: 2989604
Journal: Cancer. 1985 Mar 15;55(6):1327-33.
Title: Lymphokine-activated killer (LAK) cells. Analysis of factors relevant to the immunotherapy of human cancer.
Author: Rayner, A A|Grimm, E A|Lotze, M T|Chu, E W|Rosenberg, S A
PMID: 3871657
Journal: CMAJ. 1986 Feb 1;134(3):231-5.
Title: Cancer patterns in Canada.
Author: Wigle, D T|Mao, Y|Semenciw, R|Morrison, H I
PMID: 3942929
Journal: J Immunol. 1987 May 15;138(10):3566-72.
Title: Analysis of effector cells in human antibody-dependent cellular cytotoxicity with murine monoclonal antibodies.
Author: Ortaldo, J R|Woodhouse, C|Morgan, A C|Herberman, R B|Cheresh, D A|Reisfeld, R
PMID: 2437198
Journal: J Clin Apher. 1988;4(2-3):118-21.
Title: Ex vivo activation of killer monocytes (AKM) and their application to the treatment of human cancer.
Author: Stevenson, H C|Lacerna, L V Jr|Sugarbaker, P H
PMID: 3135291
Journal: Cancer Detect Prev. 1988;13(3-4):157-66.
Title: The National Mortality Survey of China: implications for cancer control and prevention.
Author: King, H|Locke, F B
PMID: 3242826
Journal: Cancer Immunol Immunother. 1989;28(1):43-53.
Title: Inhibition of lymphokine-activated killer cell generation by cultured tumor cell lines in vitro.
Author: Guillou, P J|Sedman, P C|Ramsden, C W
PMID: 2462468
Journal: Cancer Immunol Immunother. 1989;30(1):65-70.
Title: Cytostatic and cytotoxic activity of lymphokine-activated killer cell supernatants.
Author: Hersh, E M|Scuderi, P|Grimes, W J|Chong, A|Brailey, J L|Gschwind, C R|Salmon, S E
PMID: 2480843
Journal: J Clin Oncol. 1989 Apr;7(4):486-98.
Title: Interleukin-2 and lymphokine-activated killer cell therapy of solid tumors: analysis of toxicity and management guidelines.
Author: Margolin, K A|Rayner, A A|Hawkins, M J|Atkins, M B|Dutcher, J P|Fisher, R I|Weiss, G R|Doroshow, J H|Jaffe, H S|Roper, M
PMID: 2647914
Journal: J Surg Res. 1992 Nov;53(5):445-9.
Title: Substance P increases in vitro lymphokine-activated-killer (LAK) cell cytotoxicity against fresh colorectal cancer cells.
Author: Flageole, H|Senterman, M|Trudel, J L
PMID: 1279274
Journal: Immunobiology. 1992 Jun;185(1):63-77.
Title: Resistance of different tumor cells to lysis by lymphokine activated killer cells can be mediated by distinct mechanisms.
Author: Bean, P|Mazumder, A
PMID: 1398742
Journal: Cancer Immunol Immunother. 1993 Sep;37(4):245-50.
Title: Synergetic effect of interleukin-2 and cellular cytotoxicity against a novel tumor-associated carbohydrate antigen Le(a)/Le(a) (dimeric Le(a)) mediated by monoclonal antibody NCC-ST-421 in adoptive immunization using SCID mice.
Author: Watanabe, M|Kubota, T|Kitajima, M|Hakomori, S
PMID: 8348564
Journal: Cancer Immunol Immunother. 1994 Jun;38(6):394-8.
Title: Alteration in lymphocyte phenotype associated with administration of adjuvant levamisole and 5-fluorouracil.
Author: Holcombe, R F|Stewart, R M|Betzing, K W|Kannan, K
PMID: 7515770
Journal: Cancer Res. 1994 Jul 1;54(13):3521-6.
Title: Adenosine inhibits the adhesion of anti-CD3-activated killer lymphocytes to adenocarcinoma cells through an A3 receptor.
Author: MacKenzie, W M|Hoskin, D W|Blay, J
PMID: 8012976
Journal: Cancer Immunol Immunother. 1994 Mar;38(3):201-7.
Title: Colon adenocarcinoma cells inhibit anti-CD3-activated killer cell induction.
Author: Hoskin, D W|Reynolds, T|Blay, J
PMID: 8124689
Journal: Immunol Lett. 1995 Jan;44(1):35-40.
Title: Tumor-associated glycoantigen, sialyl Lewis(a) as a target for bispecific antibody-directed adoptive tumor immunotherapy.
Author: Ohta, S|Tsukamoto, H|Watanabe, K|Makino, K|Kuge, S|Hanai, N|Habu, S|Nishimura, T
PMID: 7721341
Journal: Crit Care Nurs Clin North Am. 1997 Dec;9(4):489-96.
Title: Myocardial infarction. The number one killer of women.
Author: Evanoski, C A
PMID: 9444172
Journal: Int J Oncol. 1997 Mar;10(3):481-6.
Title: Effects of thymic peptides, in vitro, on the impaired immunocytotoxicity of peripheral blood mononuclear cells from tumor patients.
Author: Eckert, K|Mayer, G|Stange, R|Kalden, M|Krasagakis, K|Maurer, H
PMID: 21533400
Journal: Cancer Lett. 1998 Nov 27;133(2):197-204.
Title: Genomic organization and mutation analyses of the DR5/TRAIL receptor 2 gene in colorectal carcinomas.
Author: Arai, T|Akiyama, Y|Okabe, S|Saito, K|Iwai, T|Yuasa, Y
PMID: 10072170
Journal: J Gastroenterol Hepatol. 1998 Nov;13(S3):S252-S256.
Title: Effectiveness and cost-effectiveness of colorectal cancer screening: Selecting the ideal strategy.
Author: Bond, John H
PMID: 28976679
Journal: Anticancer Res. 1999 Jan-Feb;19(1A):313-6.
Title: Combined antitumour activity of mitomycin C, 5-fluorouracil and interleukin-2 against human colon cancer cells.
Author: Ishihara, M|Kubota, T|Watanabe, M|Kawano, Y|Narai, S|Yasui, N|Otani, Y|Teramoto, T|Kitajima, M
PMID: 10226560
Journal: QJM. 2000 Mar;93(3):131-4.
Title: Colorectal cancer: still a major killer despite progress on many fronts.
Author: Shanahan, F|O'Sullivan, G C|O'Leary, C
PMID: 10751231
Journal: Mol Ther. 2000 Feb;1(2):130-44.
Title: The TRAIL decoy receptor TRUNDD (DcR2, TRAIL-R4) is induced by adenovirus-p53 overexpression and can delay TRAIL-, p53-, and KILLER/DR5-dependent colon cancer apoptosis.
Author: Meng, R D|McDonald, E R 3rd|Sheikh, M S|Fornace, A J Jr|El-Deiry, W S
PMID: 10933923
Journal: Cell Immunol. 2000 Aug 1;203(2):84-94.
Title: Cytokines secreted by lymphokine-activated killer cells induce endogenous nitric oxide synthesis and apoptosis in DLD-1 colon cancer cells.
Author: Kwak, J Y|Han, M K|Choi, K S|Park, I H|Park, S Y|Sohn, M H|Kim, U H|McGregor, J R|Samlowski, W E|Yim, C Y
PMID: 11006006
Journal: Gan To Kagaku Ryoho. 2000 Oct;27(12):1870-3.
Title: [Locoregional immunotherapy of malignant effusions for colorectal cancer using OK-432 and its acting mechanisms--possibility of molecular diagnosis using TCRCDR 3 sequence].
Author: Yamaguchi, Y|Sawamura, A|Minami, K|Miyahara, E|Toge, T
PMID: 11086433
Journal: Clin Cancer Res. 2000 Dec;6(12):4900-7.
Title: Cure of metastatic human colonic cancer in mice with radiolabeled monoclonal antibody fragments.
Author: Behr, T M|Blumenthal, R D|Memtsoudis, S|Sharkey, R M|Gratz, S|Becker, W|Goldenberg, D M
PMID: 11156250
Journal: Exp Cell Res. 2001 Jan 15;262(2):154-69.
Title: p53-independent upregulation of KILLER/DR5 TRAIL receptor expression by glucocorticoids and interferon-gamma.
Author: Meng, R D|El-Deiry, W S
PMID: 11139340
Journal: Tex Med. 2001 Feb;97(2):46-8.
Title: Colorectal cancer screening: the old and the new.
Author: Ziebert, J J
PMID: 11233058
Journal: Cancer Res. 2001 Feb 15;61(4):1645-51.
Title: Anticancer agents sensitize tumor cells to tumor necrosis factor-related apoptosis-inducing ligand-mediated caspase-8 activation and apoptosis.
Author: Lacour, S|Hammann, A|Wotawa, A|Corcos, L|Solary, E|Dimanche-Boitrel, M T
PMID: 11245478
Journal: Oncogene. 2001 Mar 22;20(12):1476-85.
Title: Sodium nitroprusside enhances TRAIL-induced apoptosis via a mitochondria-dependent pathway in human colorectal carcinoma CX-1 cells.
Author: Lee, Y J|Lee, K H|Kim, H R|Jessup, J M|Seol, D W|Kim, T H|Billiar, T R|Song, Y K
PMID: 11313891
Journal: Oncogene. 2001 Feb 1;20(5):571-80.
Title: p53 upregulates cFLIP, inhibits transcription of NF-kappaB-regulated genes and induces caspase-8-independent cell death in DLD-1 cells.
Author: Bartke, T|Siegmund, D|Peters, N|Reichwein, M|Henkler, F|Scheurich, P|Wajant, H
PMID: 11313989
Journal: Cancer Detect Prev. 2001;25(2):183-91.
Title: Investigating the role of immunomodulation for colon cancer prevention: results of an in vivo dose escalation trial of levamisole with immunologic endpoints.
Author: Holcombe, R F|Milovanovic, T|Stewart, R M|Brodhag, T M
PMID: 11341354
Journal: J Biol Chem. 2001 Oct 12;276(41):37879-86.
Title: Identification of inhibitors of TRAIL-induced death (ITIDs) in the TRAIL-sensitive colon carcinoma cell line SW480 using a genetic approach.
Author: Burns, T F|El-Deiry, W S
PMID: 11486001
Journal: Oncogene. 2001 Aug 23;20(37):5225-31.
Title: Accelerated degradation of cellular FLIP protein through the ubiquitin-proteasome pathway in p53-mediated apoptosis of human cancer cells.
Author: Fukazawa, T|Fujiwara, T|Uno, F|Teraishi, F|Kadowaki, Y|Itoshima, T|Takata, Y|Kagawa, S|Roth, J A|Tschopp, J|Tanaka, N
PMID: 11526513
Journal: Oncogene. 2002 Jan 17;21(3):337-46.
Title: Low glucose-enhanced TRAIL cytotoxicity is mediated through the ceramide-Akt-FLIP pathway.
Author: Nam, Seon Young|Amoscato, Andrew A|Lee, Yong J
PMID: 11821946
Journal: Gastroenterology. 2002 Mar;122(3):659-66.
Title: TRAIL and its receptors in the colonic epithelium: a putative role in the defense of viral infections.
Author: Strater, Jorn|Walczak, Henning|Pukrop, Tanja|Von Muller, Lutz|Hasel, Cornelia|Kornmann, Marko|Mertens, Thomas|Moller, Peter
PMID: 11874999
Journal: Nat Med. 2002 Mar;8(3):274-81.
Title: Tumor-cell resistance to death receptor--induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax.
Author: LeBlanc, Heidi|Lawrence, David|Varfolomeev, Eugene|Totpal, Klara|Morlan, John|Schow, Peter|Fong, Sharon|Schwall, Ralph|Sinicropi, Dominick|Ashkenazi, Avi
PMID: 11875499
Journal: Eur J Cancer. 2002 May;38(7):880-6.
Title: Prognosis and response to therapy in colorectal cancer.
Author: Walker, J|Quirke, P
PMID: 11978512
Journal: Oncogene. 2002 May 16;21(22):3611-9.
Title: Enhanced tumor killing by Apo2L/TRAIL and CPT-11 co-treatment is associated with p21 cleavage and differential regulation of Apo2L/TRAIL ligand and its receptors.
Author: Xiang, Hong|Fox, Judith A|Totpal, Klara|Aikawa, Mina|Dupree, Kelly|Sinicropi, Dominick|Lowe, John|Escandon, Enrique
PMID: 12032863
Journal: Cancer Biol Ther. 2002 Jan-Feb;1(1):47-55.
Title: The mutant p53-conformation modifying drug, CP-31398, can induce apoptosis of human cancer cells and can stabilize wild-type p53 protein.
Author: Takimoto, Rishu|Wang, Wenge|Dicker, David T|Rastinejad, Farzan|Lyssikatos, Joseph|el-Deiry, Wafik S
PMID: 12174820
Journal: Oncogene. 2002 Sep 5;21(39):6032-40.
Title: Apo2L/TRAIL differentially modulates the apoptotic effects of sulindac and a COX-2 selective non-steroidal anti-inflammatory agent in Bax-deficient cells.
Author: He, Qin|Luo, Xiuquan|Huang, Ying|Sheikh, M Saeed
PMID: 12203115
Journal: Cancer Res. 2002 Sep 1;62(17):4903-8.
Title: Cyclooxygenase-2 overexpression inhibits death receptor 5 expression and confers resistance to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human colon cancer cells.
Author: Tang, Ximing|Sun, Yun Jie|Half, Elizabeth|Kuo, M Tien|Sinicrope, Frank
PMID: 12208739
Journal: Cancer Res. 2002 Oct 15;62(20):5800-6.
Title: Effects of tumor necrosis factor-related apoptosis-inducing ligand alone and in combination with chemotherapeutic agents on patients' colon tumors grown in SCID mice.
Author: Naka, Takuji|Sugamura, Kenji|Hylander, Bonnie L|Widmer, Michael B|Rustum, Youcef M|Repasky, Elizabeth A
PMID: 12384541
Journal: Clin Cancer Res. 2002 Dec;8(12):3734-40.
Title: Expression of TRAIL and TRAIL receptors in colon carcinoma: TRAIL-R1 is an independent prognostic parameter.
Author: Strater, Jorn|Hinz, Ulf|Walczak, Henning|Mechtersheimer, Gunhild|Koretz, Karin|Herfarth, Christian|Moller, Peter|Lehnert, Thomas
PMID: 12473583
Journal: Cancer Res. 2003 Apr 1;63(7):1483-9.
Title: Bax plays a pivotal role in thapsigargin-induced apoptosis of human colon cancer HCT116 cells by controlling Smac/Diablo and Omi/HtrA2 release from mitochondria.
Author: Yamaguchi, Hirohito|Bhalla, Kapil|Wang, Hong-Gang
PMID: 12670894
Journal: J Natl Cancer Inst. 2003 Apr 16;95(8):611-21.
Title: Macrophages from cancer patients: analysis of TRAIL, TRAIL receptors, and colon tumor cell apoptosis.
Author: Herbeuval, Jean-Philippe|Lambert, Claude|Sabido, Odile|Cottier, Michele|Fournel, Pierre|Dy, Michel|Genin, Christian
PMID: 12697854
Journal: Oncogene. 2003 May 1;22(17):2674-9.
Title: Effect of Bax deficiency on death receptor 5 and mitochondrial pathways during endoplasmic reticulum calcium pool depletion-induced apoptosis.
Author: He, Qin|Montalbano, JoAnne|Corcoran, Chad|Jin, Weixin|Huang, Ying|Sheikh, M Saeed
PMID: 12730681
Journal: J Pathol. 2003 Jul;200(3):327-35.
Title: Expression of TRAIL (TNF-related apoptosis-inducing ligand) and its receptors in normal colonic mucosa, adenomas, and carcinomas.
Author: Koornstra, Jan J|Kleibeuker, Jan H|van Geelen, Caroline M M|Rijcken, Fleur E M|Hollema, Harry|de Vries, Elisabeth G E|de Jong, Steven
PMID: 12845629
Journal: Br J Cancer. 2003 Jul 21;89(2):363-73.
Title: Differential modulation of the TRAIL receptors and the CD95 receptor in colon carcinoma cell lines.
Author: van Geelen, C M M|de Vries, E G E|Le, T K P|van Weeghel, R P|de Jong, S
PMID: 12865931
Journal: Oncogene. 2003 Aug 7;22(32):4953-63.
Title: The proteasome inhibitor PS-341 overcomes TRAIL resistance in Bax and caspase 9-negative or Bcl-xL overexpressing cells.
Author: Johnson, Thomas R|Stone, Kimberley|Nikrad, Malti|Yeh, Tammie|Zong, Wei-Xing|Thompson, Craig B|Nesterov, Alexandre|Kraft, Andrew S
PMID: 12902978
Journal: Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):15095-100. Epub 2003 Nov 26.
Title: Requirement of p53 targets in chemosensitization of colonic carcinoma to death ligand therapy.
Author: Wang, Shulin|El-Deiry, Wafik S
PMID: 14645705
Journal: Exp Cell Res. 2004 Feb 1;293(1):129-43.
Title: Low extracellular pH augments TRAIL-induced apoptotic death through the mitochondria-mediated caspase signal transduction pathway.
Author: Lee, Yong J|Song, Jae J|Kim, Jin H|Kim, Hyeong-Reh Choi|Song, Young K
PMID: 14729063
Journal: Nurs Times. 2004 Apr 6-12;100(14):30-1.
Title: The importance of improving awareness of colorectal cancer.
Author: Jagot, Claire
PMID: 15119130
Journal: Carcinogenesis. 2004 Oct;25(10):1813-20.
Title: Sodium butyrate sensitizes TRAIL-mediated apoptosis by induction of transcription from the DR5 gene promoter through Sp1 sites in colon cancer cells.
Author: Kim, Young-Ho|Park, Jong-Wook|Lee, Jai-Youl|Kwon, Taeg Kyu
PMID: 15142888
Journal: J Biol Chem. 2004 Aug 20;279(34):35829-39. Epub 2004 May 20.
Title: Deficient tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor transport to the cell surface in human colon cancer cells selected for resistance to TRAIL-induced apoptosis.
Author: Jin, Zhaoyu|McDonald, E Robert 3rd|Dicker, David T|El-Deiry, Wafik S
PMID: 15155747
Journal: J Biol Chem. 2004 Oct 29;279(44):45495-502. Epub 2004 Aug 18.
Title: CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells.
Author: Yamaguchi, Hirohito|Wang, Hong-Gang
PMID: 15322075
Journal: Cancer Res. 2004 Sep 15;64(18):6666-72.
Title: Inducible silencing of KILLER/DR5 in vivo promotes bioluminescent colon tumor xenograft growth and confers resistance to chemotherapeutic agent 5-fluorouracil.
Author: Wang, Shulin|El-Deiry, Wafik S
PMID: 15374982
Journal: Oncogene. 2004 Nov 25;23(55):8979-86.
Title: Redistribution of CD95, DR4 and DR5 in rafts accounts for the synergistic toxicity of resveratrol and death receptor ligands in colon carcinoma cells.
Author: Delmas, Dominique|Rebe, Cedric|Micheau, Olivier|Athias, Anne|Gambert, Philippe|Grazide, Solene|Laurent, Guy|Latruffe, Norbert|Solary, Eric
PMID: 15480430
Journal: Drug Resist Updat. 2004 Dec;7(6):345-58.
Title: Lessons from TRAIL-resistance mechanisms in colorectal cancer cells: paving the road to patient-tailored therapy.
Author: Van Geelen, Caroline M M|de Vries, Elisabeth G E|de Jong, Steven
PMID: 15790545
Journal:
Title: (99m)Tc-Labeled lexatumumab
Author: Chopra, Arvind
PMID: 20641185
Journal:
Title: (99m)Tc-Labeled mapatumumab
Author: Chopra, Arvind
PMID: 20641397
Journal:
Title: (111)In-Labeled mapatumumab
Author: Chopra, Arvind
PMID: 20641403
Journal:
Title: (111)In-Labeled lexatumumab
Author: Chopra, Arvind
PMID: 20641892
Journal: J Biol Chem. 2005 Jun 17;280(24):22856-67.
Title: Transformation by oncogenic RAS sensitizes human colon cells to TRAIL-induced apoptosis by up-regulating death receptor 4 and death receptor 5 through a MEK-dependent pathway.
Author: Drosopoulos, Konstantinos G|Roberts, Michael L|Cermak, Lukas|Sasazuki, Takehiko|Shirasawa, Senji|Andera, Ladislav|Pintzas, Alexander
PMID: 15757891
Journal: Br J Cancer. 2005 Apr 25;92(8):1430-41.
Title: HGS-ETR1, a fully human TRAIL-receptor 1 monoclonal antibody, induces cell death in multiple tumour types in vitro and in vivo.
Author: Pukac, L|Kanakaraj, P|Humphreys, R|Alderson, R|Bloom, M|Sung, C|Riccobene, T|Johnson, R|Fiscella, M|Mahoney, A|Carrell, J|Boyd, E|Yao, X T|Zhang, L|Zhong, L|von Kerczek, A|Shepard, L|Vaughan, T|Edwards, B|Dobson, C|Salcedo, T|Albert, V
PMID: 15846298
Journal: Eur J Cancer. 2005 May;41(8):1195-202.
Title: Expression of tumour necrosis factor-related apoptosis-inducing ligand death receptors in sporadic and hereditary colorectal tumours: potential targets for apoptosis induction.
Author: Koornstra, Jan J|Jalving, Mathilde|Rijcken, Fleur E M|Westra, Jantine|Zwart, Nynke|Hollema, Harry|de Vries, Elisabeth G E|Hofstra, Robert W M|Plukker, John T M|de Jong, Steven|Kleibeuker, Jan H
PMID: 15911244
Journal: Cancer Biol Ther. 2005 Jul;4(7):781-6. Epub 2005 Jul 6.
Title: Proteasome inhibitors-mediated TRAIL resensitization and Bik accumulation.
Author: Zhu, Hongbo|Guo, Wei|Zhang, Lidong|Wu, Shuhong|Teraishi, Fuminori|Davis, John J|Dong, Fengqin|Fang, Bingliang
PMID: 16082182
Journal: Mol Cancer Ther. 2005 Oct;4(10):1475-83.
Title: Sulindac sulfide-induced apoptosis is enhanced by a small-molecule Bcl-2 inhibitor and by TRAIL in human colon cancer cells overexpressing Bcl-2.
Author: Sinicrope, Frank A|Penington, Robert C
PMID: 16227396
Journal: Cancer Res. 2005 Dec 15;65(24):11447-58.
Title: Cyclooxygenase-2 inhibition sensitizes human colon carcinoma cells to TRAIL-induced apoptosis through clustering of DR5 and concentrating death-inducing signaling complex components into ceramide-enriched caveolae.
Author: Martin, Sophie|Phillips, Darren C|Szekely-Szucs, Kinga|Elghazi, Lynda|Desmots, Fabienne|Houghton, Janet A
PMID: 16357153
Journal: Mol Cancer Ther. 2005 Dec;4(12):2026-36.
Title: Chemotherapy and TRAIL-mediated colon cancer cell death: the roles of p53, TRAIL receptors, and c-FLIP.
Author: Galligan, Leeona|Longley, Daniel B|McEwan, Miranda|Wilson, Timothy R|McLaughlin, Kirsty|Johnston, Patrick G
PMID: 16373718
Journal: Oncogene. 2006 Feb 9;25(6):838-48.
Title: c-FLIP inhibits chemotherapy-induced colorectal cancer cell death.
Author: Longley, D B|Wilson, T R|McEwan, M|Allen, W L|McDermott, U|Galligan, L|Johnston, P G
PMID: 16247474
Journal: Mol Cell Proteomics. 2006 Jun;5(6):1119-30.
Title: Proteomic analysis of colorectal cancer reveals alterations in metabolic pathways: mechanism of tumorigenesis.
Author: Bi, Xuezhi|Lin, Qingsong|Foo, Tet Wei|Joshi, Shashikant|You, Tao|Shen, Han-Ming|Ong, Choon Nam|Cheah, Peh Yean|Eu, Kong Weng|Hew, Choy-Leong
PMID: 16554294
Journal: Oncogene. 2006 Sep 14;25(41):5640-7. Epub 2006 Apr 17.
Title: Proline oxidase activates both intrinsic and extrinsic pathways for apoptosis: the role of ROS/superoxides, NFAT and MEK/ERK signaling.
Author: Liu, Y|Borchert, G L|Surazynski, A|Hu, C-A|Phang, J M
PMID: 16619034
Journal: Mol Carcinog. 2006 Jun;45(6):447-54.
Title: Targeting cyclooxygenase-2 for prevention and therapy of colorectal cancer.
Author: Sinicrope, Frank A
PMID: 16688727
Journal: Proc Natl Acad Sci U S A. 2006 Jul 18;103(29):11003-8.
Title: Small-molecule modulators of p53 family signaling and antitumor effects in p53-deficient human colon tumor xenografts.
Author: Wang, Wenge|Kim, Seok-Hyun|El-Deiry, Wafik S
PMID: 16835297
Journal: Cancer Res. 2006 Dec 1;66(23):11115-9.
Title: Cellular FLICE-inhibitory protein down-regulation contributes to celecoxib-induced apoptosis in human lung cancer cells.
Author: Liu, Xiangguo|Yue, Ping|Schonthal, Axel H|Khuri, Fadlo R|Sun, Shi-Yong
PMID: 17145853
Journal: Radiol Clin North Am. 2007 Jan;45(1):85-118.
Title: Update on colorectal cancer imaging.
Author: Gollub, Marc J|Schwartz, Lawrence H|Akhurst, Tim
PMID: 17157625
Journal: Int J Oncol. 2007 Mar;30(3):679-87.
Title: Fenretinide up-regulates DR5/TRAIL-R2 expression via the induction of the transcription factor CHOP and combined treatment with fenretinide and TRAIL induces synergistic apoptosis in colon cancer cell lines.
Author: Kouhara, Junji|Yoshida, Tatsushi|Nakata, Susumu|Horinaka, Mano|Wakada, Miki|Ueda, Yuji|Yamagishi, Hisakazu|Sakai, Toshiyuki
PMID: 17273769
Journal: Ai Zheng. 2007 Mar;26(3):264-9.
Title: [Mechanism study of antisense cyclin B1 in tumorigenesis inhibition using proteomic technique].
Author: Yang, Tao|Zhang, Ling|Yan, Fei|Tong, Ai-Ping|Liu, Xin-Yu|Liu, Huan-Yi|Huang, Can-Hua
PMID: 17355788
Journal: Cancer Res. 2007 May 15;67(10):4774-82.
Title: Carcinoembryonic antigen inhibits anoikis in colorectal carcinoma cells by interfering with TRAIL-R2 (DR5) signaling.
Author: Samara, Raed N|Laguinge, Luciana M|Jessup, J Milburn
PMID: 17510406
Journal: Br J Cancer. 2007 Jul 2;97(1):73-84. Epub 2007 Jun 5.
Title: Newly established tumourigenic primary human colon cancer cell lines are sensitive to TRAIL-induced apoptosis in vitro and in vivo.
Author: Oikonomou, E|Kothonidis, K|Taoufik, E|Probert, E|Zografos, G|Nasioulas, G|Andera, L|Pintzas, A
PMID: 17551494
Journal: Cancer Res. 2007 Jun 15;67(12):5754-62.
Title: c-FLIP: a key regulator of colorectal cancer cell death.
Author: Wilson, Timothy R|McLaughlin, Kirsty M|McEwan, Miranda|Sakai, Hidekazu|Rogers, Katherine M A|Redmond, Kelly M|Johnston, Patrick G|Longley, Daniel B
PMID: 17575142
Journal: Mol Cancer Res. 2007 Jun;5(6):615-25.
Title: Halocynthiaxanthin and peridinin sensitize colon cancer cell lines to tumor necrosis factor-related apoptosis-inducing ligand.
Author: Yoshida, Tatsushi|Maoka, Takashi|Das, Swadesh K|Kanazawa, Kazuki|Horinaka, Mano|Wakada, Miki|Satomi, Yoshiko|Nishino, Hoyoku|Sakai, Toshiyuki
PMID: 17579120
Journal: Cancer Res. 2007 Jul 15;67(14):6987-94.
Title: Histone deacetylase inhibitors enhance lexatumumab-induced apoptosis via a p21Cip1-dependent decrease in survivin levels.
Author: Nawrocki, Steffan T|Carew, Jennifer S|Douglas, Leslie|Cleveland, John L|Humphreys, Robin|Houghton, Janet A
PMID: 17638911
Journal: Cancer Sci. 2007 Sep;98(9):1417-23.
Title: Lipoxygenase inhibitors induce death receptor 5/TRAIL-R2 expression and sensitize malignant tumor cells to TRAIL-induced apoptosis.
Author: Yoshida, Tatsushi|Shiraishi, Takumi|Horinaka, Mano|Nakata, Susumu|Yasuda, Takashi|Goda, Ahmed E|Wakada, Miki|Mizutani, Yoichi|Miki, Tsuneharu|Nishikawa, Akiyoshi|Sakai, Toshiyuki
PMID: 17645780
Journal: Clin Lung Cancer. 2007 Jul;8(7):413-9.
Title: The potential of death receptor 4- and 5-directed therapies in the treatment of lung cancer.
Author: Camidge, D Ross
PMID: 17681093
Journal: Clin Cancer Res. 2007 Sep 1;13(17):5070-5.
Title: Overexpression of FLIPL is an independent marker of poor prognosis in colorectal cancer patients.
Author: Ullenhag, Gustave J|Mukherjee, Abhik|Watson, Nicholas F S|Al-Attar, Ahmad H|Scholefield, John H|Durrant, Lindy G
PMID: 17785559
Journal: Mol Cancer Ther. 2007 Sep;6(9):2591-9.
Title: Quercetin enhances TRAIL-mediated apoptosis in colon cancer cells by inducing the accumulation of death receptors in lipid rafts.
Author: Psahoulia, Faiy H|Drosopoulos, Konstantinos G|Doubravska, Lenka|Andera, Ladislav|Pintzas, Alexander
PMID: 17876056
Journal: Cancer Biol Ther. 2007 Sep;6(9):1490-5. Epub 2007 Aug 17.
Title: Chemotherapy-resistant side-population of colon cancer cells has a higher sensitivity to TRAIL than the non-SP, a higher expression of c-Myc and TRAIL-receptor DR4.
Author: Sussman, Robyn T|Ricci, M Stacey|Hart, Lori S|Sun, Shi Yong|El-Deiry, Wafik S
PMID: 17881904
Journal: Int J Oncol. 2007 Dec;31(6):1391-402.
Title: Differential response of p53 and p21 on HDAC inhibitor-mediated apoptosis in HCT116 colon cancer cells in vitro and in vivo.
Author: Zopf, Steffen|Neureiter, Daniel|Bouralexis, Steve|Abt, Tobias|Glaser, Keith B|Okamoto, Kinya|Ganslmayer, Marion|Hahn, Eckhart G|Herold, Christoph|Ocker, Matthias
PMID: 17982666
Journal: Int J Oncol. 2007 Dec;31(6):1491-500.
Title: Apoptosis, cell cycle progression and gene expression in TP53-depleted HCT116 colon cancer cells in response to short-term 5-fluorouracil treatment.
Author: Adamsen, Birgitte Lid|Kravik, Katherine L|Clausen, Ole P F|De Angelis, Paula M
PMID: 17982676
Journal: Mol Carcinog. 2008 Apr;47(4):252-63.
Title: 1,1-bis(3'-indolyl)-1-(p-methoxyphenyl)methane activates Nur77-independent proapoptotic responses in colon cancer cells.
Author: Cho, Sung Dae|Lei, Ping|Abdelrahim, Maen|Yoon, Kyungsil|Liu, Shengxi|Guo, Jingjing|Papineni, Sabitha|Chintharlapalli, Sudhakar|Safe, Stephen
PMID: 17957723
Journal: World J Gastroenterol. 2008 Feb 14;14(6):853-63.
Title: Colonography by CT, MRI and PET/CT combined with conventional colonoscopy in colorectal cancer screening and staging.
Author: Sun, Long|Wu, Hua|Guan, Yong-Song
PMID: 18240342
Journal: Cancer Res. 2008 Feb 1;68(3):880-8.
Title: Systematic high-content proteomic analysis reveals substantial immunologic changes in colorectal cancer.
Author: Berndt, Uta|Philipsen, Lars|Bartsch, Sebastian|Wiedenmann, Bertram|Baumgart, Daniel C|Hammerle, Marcus|Sturm, Andreas
PMID: 18245490
Journal: Cancer Res. 2008 Feb 1;68(3):909-17.
Title: DR5 receptor mediates anoikis in human colorectal carcinoma cell lines.
Author: Laguinge, Luciana M|Samara, Raed N|Wang, Wenge|El-Deiry, Wafik S|Corner, Georgia|Augenlicht, Leonard|Mishra, Lopa|Jessup, J Milburn
PMID: 18245494
Journal: Ann Oncol. 2008 Jun;19(6):1060-7.
Title: A novel humanized anti-human death receptor 5 antibody CS-1008 induces apoptosis in tumor cells without toxicity in hepatocytes.
Author: Yada, A|Yazawa, M|Ishida, S|Yoshida, H|Ichikawa, K|Kurakata, S|Fujiwara, K
PMID: 18304965
Journal: Biochem Pharmacol. 2008 May 1;75(9):1729-42.
Title: Critical role of Bid and Bax in indirubin-3'-monoxime-induced apoptosis in human cancer cells.
Author: Shi, Jie|Shen, Han-Ming
PMID: 18377873
Journal: Clin Cancer Res. 2008 Apr 1;14(7):2180-9.
Title: Treatment of human colon cancer xenografts with TRA-8 anti-death receptor 5 antibody alone or in combination with CPT-11.
Author: Oliver, Patsy G|LoBuglio, Albert F|Zinn, Kurt R|Kim, Hyunki|Nan, Li|Zhou, Tong|Wang, Wenquan|Buchsbaum, Donald J
PMID: 18381960
Journal: Carcinogenesis. 2008 Jun;29(6):1139-47.
Title: 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes inhibit colon cancer cell and tumor growth through activation of c-jun N-terminal kinase.
Author: Lei, Ping|Abdelrahim, Maen|Cho, Sung Dae|Liu, Shengxi|Chintharlapalli, Sudhakar|Safe, Stephen
PMID: 18460448
Journal: Bull Cancer. 2008 May 28;95 FMC Onco:F7-10.
Title: [Frequency of cancer at older ages].
Author: Hill, Catherine|Doyon, Francoise
PMID: 18511360
Journal: BMC Cancer. 2008 Jul 1;8:187.
Title: Metastatic susceptibility locus, an 8p hot-spot for tumour progression disrupted in colorectal liver metastases: 13 candidate genes examined at the DNA, mRNA and protein level.
Author: Macartney-Coxson, Donia P|Hood, Kylie A|Shi, Hong-jun|Ward, Teresa|Wiles, Anna|O'Connor, Rosemary|Hall, David A|Lea, Rod A|Royds, Janice A|Stubbs, Richard S|Rooker, Serena
PMID: 18590575
Journal: Cancer Res. 2008 Jul 1;68(13):4977-82.
Title: Single-cell transcription site activation predicts chemotherapy response in human colorectal tumors.
Author: Pezo, Rossanna C|Gandhi, Saumil J|Shirley, L Andrew|Pestell, Richard G|Augenlicht, Leonard H|Singer, Robert H
PMID: 18593893
Journal: Biochem Biophys Res Commun. 2008 Oct 10;375(1):129-33.
Title: Kaempferol sensitizes colon cancer cells to TRAIL-induced apoptosis.
Author: Yoshida, Tatsushi|Konishi, Masako|Horinaka, Mano|Yasuda, Takashi|Goda, Ahmed E|Taniguchi, Hiroya|Yano, Kimihiro|Wakada, Miki|Sakai, Toshiyuki
PMID: 18680719
Journal: Oncology. 2008;74(3-4):188-97.
Title: Synergism of CPT-11 and Apo2L/TRAIL against two differentially sensitive human colon tumor xenografts.
Author: Sugamura, Kenji|Gibbs, John F|Belicha-Villanueva, Alan|Andrews, Christopher|Repasky, Elizabeth A|Hylander, Bonnie L
PMID: 18714167
Journal: Apoptosis. 2008 Oct;13(10):1232-42.
Title: Lupulone, a hop bitter acid, activates different death pathways involving apoptotic TRAIL-receptors, in human colon tumor cells and in their derived metastatic cells.
Author: Lamy, Virginie|Roussi, Stamatiki|Chaabi, Mehdi|Gosse, Francine|Lobstein, Annelise|Raul, Francis
PMID: 18726190
Journal: Mol Cancer Ther. 2008 Oct;7(10):3429-40.
Title: 15-deoxy-Delta12,14-prostaglandin J2 up-regulates death receptor 5 gene expression in HCT116 cells: involvement of reactive oxygen species and C/EBP homologous transcription factor gene transcription.
Author: Su, Rong-Ying|Chi, Kwan-Hwa|Huang, Duen-Yi|Tai, Ming-Hui|Lin, Wan-Wan
PMID: 18852146
Journal: Cancer Res. 2008 Nov 1;68(21):8918-27.
Title: Baicalein overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance via two different cell-specific pathways in cancer cells but not in normal cells.
Author: Taniguchi, Hiroya|Yoshida, Tatsushi|Horinaka, Mano|Yasuda, Takashi|Goda, Ahmed E|Konishi, Masako|Wakada, Miki|Kataoka, Keisho|Yoshikawa, Toshikazu|Sakai, Toshiyuki
PMID: 18974136
Journal: Cancer Biol Ther. 2008 Dec;7(12):2039-46.
Title: Non-genotoxic anti-neoplastic effects of ellipticine derivative NSC176327 in p53-deficient human colon carcinoma cells involve stimulation of p73.
Author: Lu, Chao|Wang, Wenge|El-Deiry, Wafik S
PMID: 19106635
Journal: Environ Health Prev Med. 2008 Sep;13(5):281-7.
Title: Combination of isoliquiritigenin and tumor necrosis factor-related apoptosis-inducing ligand induces apoptosis in colon cancer HT29 cells.
Author: Yoshida, Tatsushi|Horinaka, Mano|Takara, Mami|Tsuchihashi, Mayuko|Mukai, Nobuhiro|Wakada, Miki|Sakai, Toshiyuki
PMID: 19568915
Journal: Cancer Chemother Pharmacol. 2009 Oct;64(5):953-60.
Title: Prostaglandin synthase 2/cyclooxygenase 2 (PTGS2/COX2) 8473T>C polymorphism associated with prognosis for patients with colorectal cancer treated with capecitabine and oxaliplatin.
Author: Kim, Jong Gwang|Chae, Yee Soo|Sohn, Sang Kyun|Moon, Joon Ho|Ryoo, Hun Mo|Bae, Sung Hwa|Kum, Yoonseop|Jeon, Seong Woo|Lim, Kyoung-Hoon|Kang, Byung-Mo|Park, In-Ja|Choi, Gyu Seog|Jun, Soo-Han
PMID: 19219602
Journal: Strahlenther Onkol. 2009 Jan;185(1):8-18.
Title: Efficacy of a triple treatment with irradiation, agonistic TRAIL receptor antibodies and EGFR blockade.
Author: Niyazi, Maximilian|Marini, Patrizia|Daniel, Peter T|Humphreys, Robin|Jendrossek, Verena|Belka, Claus
PMID: 19224142
Journal: Am J Physiol Gastrointest Liver Physiol. 2009 May;296(5):G1060-8.
Title: Induction of p53 contributes to apoptosis of HCT-116 human colon cancer cells induced by the dietary compound fisetin.
Author: Lim, Do Y|Park, Jung Han Yoon
PMID: 19264955
Journal: Br J Cancer. 2009 May 5;100(9):1415-24.
Title: Differential activation of JNK1 isoforms by TRAIL receptors modulate apoptosis of colon cancer cell lines.
Author: Mahalingam, D|Keane, M|Pirianov, G|Mehmet, H|Samali, A|Szegezdi, E
PMID: 19352384
Journal: Oncol Rep. 2009 Jun;21(6):1455-60.
Title: Efficacy of triple therapies including ionising radiation, agonistic TRAIL antibodies and cisplatin.
Author: Niyazi, Maximilian|Marini, Patrizia|Daniel, Peter T|Humphreys, Robin|Jendrossek, Verena|Belka, Claus
PMID: 19424623
Journal: Biochem Pharmacol. 2009 May 1;77(9):1487-96.
Title: A rice bran polyphenol, cycloartenyl ferulate, elicits apoptosis in human colorectal adenocarcinoma SW480 and sensitizes metastatic SW620 cells to TRAIL-induced apoptosis.
Author: Kong, Carrie K L|Lam, W S|Chiu, Lawrence C M|Ooi, Vincent E C|Sun, Samuel S M|Wong, Yum-Shing
PMID: 19426686
Journal: J Cell Mol Med. 2009 Nov-Dec;13(11-12):4409-14.
Title: Stem cells are resistant to TRAIL receptor-mediated apoptosis.
Author: Szegezdi, Eva|O'Reilly, Aoife|Davy, Yeung|Vawda, Reaz|Taylor, Deanna L|Murphy, Mary|Samali, Afshin|Mehmet, Huseyin
PMID: 19604313
Journal: Int J Cancer. 2009 Nov 1;125(9):2127-35.
Title: TRAIL receptor upregulation and the implication of KRAS/BRAF mutations in human colon cancer tumors.
Author: Oikonomou, Eftychia|Kosmidou, Vivian|Katseli, Anastasia|Kothonidis, Konstantinos|Mourtzoukou, Despina|Kontogeorgos, George|Andera, Ladislav|Zografos, Georgios|Pintzas, Alexander
PMID: 19637313
Journal: Cancer Prev Res (Phila). 2009 Aug;2(8):732-42.
Title: Regulation of colorectal cancer cell apoptosis by the n-3 polyunsaturated fatty acids Docosahexaenoic and Eicosapentaenoic.
Author: Giros, Anna|Grzybowski, Mike|Sohn, Vanessa R|Pons, Elisenda|Fernandez-Morales, Jessica|Xicola, Rosa M|Sethi, Puja|Grzybowski, Jessica|Goel, Ajay|Boland, C Richard|Gassull, Miquel A|Llor, Xavier
PMID: 19638488
Journal: Cancer Res. 2009 Aug 15;69(16):6581-9.
Title: Zerumbone enhances TRAIL-induced apoptosis through the induction of death receptors in human colon cancer cells: Evidence for an essential role of reactive oxygen species.
Author: Yodkeeree, Supachai|Sung, Bokyung|Limtrakul, Pornngarm|Aggarwal, Bharat B
PMID: 19654295
Journal: Nihon Rinsho Meneki Gakkai Kaishi. 2009 Aug;32(4):223-30.
Title: [Discovery of a new type of human regulatory T cell lines, HOZOTs, and their clinical application]].
Author: Nakamura, Shuji
PMID: 19721342
Journal: J Immunol. 2009 Oct 1;183(7):4371-7.
Title: Phosphorothioate-modified TLR9 ligands protect cancer cells against TRAIL-induced apoptosis.
Author: Chiron, David|Pellat-Deceunynck, Catherine|Maillasson, Mike|Bataille, Regis|Jego, Gaetan
PMID: 19734228
Journal: Mol Cell Pharmacol. 2009;1(1):23-28.
Title: Smac deficiency affects endoplasmic reticulum stress-induced apoptosis in human colon cancer cells.
Author: He, Qin|Shi, Jingxue|Jones, Samantha|An, Jie|Liu, Yuxin|Huang, Ying|Sheikh, M Saeed
PMID: 20209078
Journal: Mol Cell Pharmacol. 2009 Jan 1;1(2):92-97.
Title: Sulindac Sulfide Differentially Induces Apoptosis in Smac-Proficient and -Deficient Human Colon Cancer Cells.
Author: Shi, Jingxue|He, Qin|An, Jie|Sun, Hong|Huang, Ying|Sheikh, M Saeed
PMID: 20419043
Journal: Cancer Lett. 2010 Jan 1;287(1):98-108.
Title: Nutlin-3 enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through up-regulation of death receptor 5 (DR5) in human sarcoma HOS cells and human colon cancer HCT116 cells.
Author: Hori, Takeshi|Kondo, Takashi|Kanamori, Masahiko|Tabuchi, Yoshiaki|Ogawa, Ryohei|Zhao, Qing-Li|Ahmed, Kanwal|Yasuda, Taketoshi|Seki, Shoji|Suzuki, Kayo|Kimura, Tomoatsu
PMID: 19577358
Journal: Biochem Biophys Res Commun. 2010 Jan 8;391(2):1274-9.
Title: Hypoxia-induced decoy receptor 2 gene expression is regulated via a hypoxia-inducible factor 1alpha-mediated mechanism.
Author: Pei, Guo-Ting|Wu, Chi-Wei|Lin, Wan-Wan
PMID: 20018172
Journal: Br J Cancer. 2010 Feb 16;102(4):754-64.
Title: Early growth response-1 is a regulator of DR5-induced apoptosis in colon cancer cells.
Author: Mahalingam, D|Natoni, A|Keane, M|Samali, A|Szegezdi, E
PMID: 20087343
Journal: Cancer Res. 2010 Feb 1;70(3):1101-10.
Title: Multivalent DR5 peptides activate the TRAIL death pathway and exert tumoricidal activity.
Author: Pavet, Valeria|Beyrath, Julien|Pardin, Christophe|Morizot, Alexandre|Lechner, Marie-Charlotte|Briand, Jean-Paul|Wendland, Miriam|Maison, Wolfgang|Fournel, Sylvie|Micheau, Olivier|Guichard, Gilles|Gronemeyer, Hinrich
PMID: 20103630
Journal: Cancer Biol Ther. 2010 Apr 15;9(8):618-31. Epub 2010 Apr 20.
Title: Conatumumab, a fully human agonist antibody to death receptor 5, induces apoptosis via caspase activation in multiple tumor types.
Author: Kaplan-Lefko, Paula J|Graves, Jonathan D|Zoog, Stephen J|Pan, Yang|Wall, Jason|Branstetter, Daniel G|Moriguchi, Jodi|Coxon, Angela|Huard, Justin N|Xu, Ren|Peach, Matthew L|Juan, Gloria|Kaufman, Stephen|Chen, Qing|Bianchi, Allison|Kordich, Jennifer J|Ma, M
PMID: 20150762
Journal: FEBS J. 2010 Apr;277(7):1653-65.
Title: Synthetic constrained peptide selectively binds and antagonizes death receptor 5.
Author: Vrielink, Johanna|Heins, Mariette S|Setroikromo, Rita|Szegezdi, Eva|Mullally, Margaret M|Samali, Afshin|Quax, Wim J
PMID: 20156289
Journal: Mol Cancer Ther. 2010 Apr;9(4):833-43.
Title: beta-Ionone enhances TRAIL-induced apoptosis in hepatocellular carcinoma cells through Sp1-dependent upregulation of DR5 and downregulation of NF-kappaB activity.
Author: Kim, Mun-Ock|Moon, Dong-Oh|Kang, Chang-Hee|Kwon, Taeg Kyu|Choi, Yung Hyun|Kim, Gi-Young
PMID: 20354117
Journal: Clin Cancer Res. 2010 Apr 15;16(8):2320-32.
Title: Histone deacetylase inhibitors and 15-deoxy-Delta12,14-prostaglandin J2 synergistically induce apoptosis.
Author: Koyama, Makoto|Izutani, Yasuyuki|Goda, Ahmed E|Matsui, Taka-aki|Horinaka, Mano|Tomosugi, Mitsuhiro|Fujiwara, Jun|Nakamura, Yoshitaka|Wakada, Miki|Yogosawa, Shingo|Sowa, Yoshihiro|Sakai, Toshiyuki
PMID: 20371690
Journal: Eur J Cancer. 2010 Jun;46(9):1703-11.
Title: Cytotoxic drugs up-regulate epidermal growth factor receptor (EGFR) expression in colon cancer cells and enhance their susceptibility to EGFR-targeted antibody-dependent cell-mediated-cytotoxicity (ADCC).
Author: Correale, Pierpaolo|Marra, Monica|Remondo, Cinzia|Migali, Cristina|Misso, Gabriella|Arcuri, Felice Paolo|Del Vecchio, Maria Teresa|Carducci, Antonietta|Loiacono, Lucia|Tassone, Pierfrancesco|Abbruzzese, Alberto|Tagliaferri, Pierosandro|Caraglia, Michele
PMID: 20399639
Journal: Mutat Res. 2010 Nov 10;693(1-2):46-52.
Title: High-throughput SNP/CGH approaches for the analysis of genomic instability in colorectal cancer.
Author: Brenner, Bruce M|Rosenberg, Daniel
PMID: 20416328
Journal: Int J Oncol. 2010 Jun;36(6):1485-90.
Title: Identification of gene expression profiles correlated to tumor progression in a preclinical model of colon carcinogenesis.
Author: Bousserouel, Souad|Kauntz, Henriette|Gosse, Francine|Bouhadjar, Mourad|Soler, Luc|Marescaux, Jacques|Raul, Francis
PMID: 20428773
Journal: Clin Cancer Res. 2010 Jul 1;16(13):3442-51.
Title: Prognostic significance of TRAIL signaling molecules in stage II and III colorectal cancer.
Author: McLornan, Donal P|Barrett, Helen L|Cummins, Robert|McDermott, Ultan|McDowell, Cliona|Conlon, Susie J|Coyle, Victoria M|Van Schaeybroeck, Sandra|Wilson, Richard|Kay, Elaine W|Longley, Daniel B|Johnston, Patrick G
PMID: 20570920
Journal: Mol Cancer. 2010 Jul 30;9:203.
Title: Prognostic significance of TRAIL death receptors in Middle Eastern colorectal carcinomas and their correlation to oncogenic KRAS alterations.
Author: Bavi, Prashant|Prabhakaran, Sarita E|Abubaker, Jehad|Qadri, Zeeshan|George, Thara|Al-Sanea, Nasser|Abduljabbar, Alaa|Ashari, Luai H|Alhomoud, Samar|Al-Dayel, Fouad|Hussain, Azhar R|Uddin, Shahab|Al-Kuraya, Khawla S
PMID: 20673328
Journal: Int J Oncol. 2010 Oct;37(4):1031-41.
Title: Downregulation of active caspase 8 as a mechanism of acquired TRAIL resistance in mismatch repair-proficient colon carcinoma cell lines.
Author: Van Geelen, Caroline M M|Pennarun, Bodvael|Ek, Wytske Boerma-Van|Le, Phuong T K|Spierings, Diana C J|De Vries, Elisabeth G E|De Jong, Steven
PMID: 20811726
Journal: J Biol Chem. 2010 Nov 12;285(46):35418-27.
Title: Gossypol induces death receptor-5 through activation of the ROS-ERK-CHOP pathway and sensitizes colon cancer cells to TRAIL.
Author: Sung, Bokyung|Ravindran, Jayaraj|Prasad, Sahdeo|Pandey, Manoj K|Aggarwal, Bharat B
PMID: 20837473
Journal: Clin Cancer Res. 2010 Dec 1;16(23):5883-91.
Title: A first-in-human study of conatumumab in adult patients with advanced solid tumors.
Author: Herbst, Roy S|Kurzrock, Razelle|Hong, David S|Valdivieso, Manuel|Hsu, Cheng-Pang|Goyal, Lovely|Juan, Gloria|Hwang, Yuying C|Wong, Susan|Hill, John S|Friberg, Greg|LoRusso, Patricia M
PMID: 20947515
Journal: Anal Cell Pathol (Amst). 2010;33(5):229-44.
Title: Inhibition of IGF-1R-dependent PI3K activation sensitizes colon cancer cells specifically to DR5-mediated apoptosis but not to rhTRAIL.
Author: Pennarun, Bodvael|Kleibeuker, Jan H|Oenema, Tjitske|Stegehuis, Janet H|de Vries, Elisabeth G E|de Jong, Steven
PMID: 20978316
Journal: Biomedica. 2010 Oct-Dec;30(4):577-86.
Title: Implication of NF-kappaB and p53 in the expression of TRAIL-death receptors and apoptosis by apple procyanidins in human metastatic SW620 cells.
Author: Maldonado, Maria Elena|Bousserouel, Souad|Gosse, Francine|Lobstein, Annelise|Raul, Francis
PMID: 21713362
Journal: Carcinogenesis. 2011 Jan;32(1):42-51.
Title: Cisplatin and a potent platinum(IV) complex-mediated enhancement of TRAIL-induced cancer cells killing is associated with modulation of upstream events in the extrinsic apoptotic pathway.
Author: Vondalova Blanarova, Olga|Jelinkova, Iva|Szoor, Arpad|Skender, Belma|Soucek, Karel|Horvath, Viktor|Vaculova, Alena|Andera, Ladislav|Sova, Petr|Szollosi, Janos|Hofmanova, Jirina|Vereb, Gyorgy|Kozubik, Alois
PMID: 21037225
Journal: Cancer Res. 2011 Jan 15;71(2):538-49.
Title: ROS and CHOP are critical for dibenzylideneacetone to sensitize tumor cells to TRAIL through induction of death receptors and downregulation of cell survival proteins.
Author: Prasad, Sahdeo|Yadav, Vivek R|Ravindran, Jayaraj|Aggarwal, Bharat B
PMID: 21127198
Journal: Cancer Res. 2011 Feb 1;71(3):1092-102.
Title: Hedgehog signaling drives cellular survival in human colon carcinoma cells.
Author: Mazumdar, Tapati|DeVecchio, Jennifer|Shi, Ting|Jones, Janay|Agyeman, Akwasi|Houghton, Janet A
PMID: 21135115
Journal: Oncol Rep. 2011 Feb;25(2):419-24.
Title: Death receptor 5-mediated TNFR family signaling pathways modulate gamma-humulene-induced apoptosis in human colorectal cancer HT29 cells.
Author: Lan, Yu-Hsuan|Wu, Yang-Chang|Wu, Kai-Wei|Chung, Jing-Gung|Lu, Chi-Cheng|Chen, Yuan-Liang|Wu, Tian-Shung|Yang, Jai-Sing
PMID: 21152878
Journal: J Biol Chem. 2011 Feb 18;286(7):5546-57.
Title: Ursolic acid, a pentacyclin triterpene, potentiates TRAIL-induced apoptosis through p53-independent up-regulation of death receptors: evidence for the role of reactive oxygen species and JNK.
Author: Prasad, Sahdeo|Yadav, Vivek R|Kannappan, Ramaswamy|Aggarwal, Bharat B
PMID: 21156789
Journal: Cancer Lett. 2011 Feb 28;301(2):193-202.
Title: Diosgenin induces death receptor-5 through activation of p38 pathway and promotes TRAIL-induced apoptosis in colon cancer cells.
Author: Lepage, C|Leger, D Y|Bertrand, J|Martin, F|Beneytout, J L|Liagre, B
PMID: 21195543
Journal: BMC Cancer. 2011 Jan 27;11:39.
Title: Modulation of TRAIL resistance in colon carcinoma cells: different contributions of DR4 and DR5.
Author: van Geelen, Caroline Mm|Pennarun, Bodvael|Le, Phuong Tk|de Vries, Elisabeth Ge|de Jong, Steven
PMID: 21272366
Journal: Cancer Lett. 2011 Mar 28;302(2):119-27.
Title: Adeno-associated virus-mediated anti-DR5 chimeric antibody expression suppresses human tumor growth in nude mice.
Author: Lv, Fujia|Qiu, Yuhe|Zhang, Yaxi|Liu, Shilian|Shi, Juan|Liu, Yanxin|Zheng, Dexian
PMID: 21306822
Journal: Carcinogenesis. 2011 May;32(5):723-31.
Title: Lipid raft-dependent death receptor 5 (DR5) expression and activation are critical for ursodeoxycholic acid-induced apoptosis in gastric cancer cells.
Author: Lim, Sung-Chul|Duong, Hong-Quan|Choi, Jeong Eun|Lee, Tae-Bum|Kang, Ju-Hee|Oh, Seung Hyun|Han, Song Iy
PMID: 21362627
Journal: Br J Pharmacol. 2011 Nov;164(5):1433-44.
Title: Methyl jasmonate down-regulates survivin expression and sensitizes colon carcinoma cells towards TRAIL-induced cytotoxicity.
Author: Raviv, Z|Zilberberg, A|Cohen, S|Reischer-Pelech, D|Horrix, C|Berger, M R|Rosin-Arbesfeld, R|Flescher, E
PMID: 21486277
Journal: Mol Cancer. 2011 Apr 25;10:46.
Title: High susceptibility of metastatic cells derived from human prostate and colon cancer cells to TRAIL and sensitization of TRAIL-insensitive primary cells to TRAIL by 4,5-dimethoxy-2-nitrobenzaldehyde.
Author: Kim, Hak-Bong|Kim, Mi-Ju|Kim, Dae-Young|Lee, Jae-Won|Bae, Jae-Ho|Kim, Dong-Wan|Kang, Chi-Dug|Kim, Sun-Hee
PMID: 21513580
Journal: Oncol Rep. 2011 Jul;26(1):109-14.
Title: Lupulone triggers p38 MAPK-controlled activation of p53 and of the TRAIL receptor apoptotic pathway in human colon cancer-derived metastatic cells.
Author: Lamy, Virginie|Bousserouel, Souad|Gosse, Francine|Minker, Carole|Lobstein, Annelise|Raul, Francis
PMID: 21519792
Journal: Cell Oncol (Dordr). 2011 Jun;34(3):245-59.
Title: Inhibition of IGF-1R-dependent PI3K activation sensitizes colon cancer cells specifically to DR5-mediated apoptosis but not to rhTRAIL.
Author: Pennarun, Bodvael|Kleibeuker, Jan H|Oenema, Tjitske|Stegehuis, Janet H|de Vries, Elisabeth G E|de Jong, Steven
PMID: 21538027
Journal: J Biol Chem. 2011 Jul 1;286(26):22982-90.
Title: Sialylation of the Fas death receptor by ST6Gal-I provides protection against Fas-mediated apoptosis in colon carcinoma cells.
Author: Swindall, Amanda F|Bellis, Susan L
PMID: 21550977
Journal: Sci Transl Med. 2011 Jun 8;3(86):86ra50.
Title: Off-target lapatinib activity sensitizes colon cancer cells through TRAIL death receptor up-regulation.
Author: Dolloff, Nathan G|Mayes, Patrick A|Hart, Lori S|Dicker, David T|Humphreys, Robin|El-Deiry, Wafik S
PMID: 21653830
Journal: Cell Cycle. 2011 Jul 15;10(14):2380-9.
Title: The relative contribution of pro-apoptotic p53-target genes in the triggering of apoptosis following DNA damage in vitro and in vivo.
Author: Kuribayashi, Kageaki|Finnberg, Niklas|Jeffers, John R|Zambetti, Gerard P|El-Deiry, Wafik S
PMID: 21709442
Journal: PLoS One. 2011;6(6):e21632.
Title: Selective BRAFV600E inhibitor PLX4720, requires TRAIL assistance to overcome oncogenic PIK3CA resistance.
Author: Oikonomou, Eftychia|Koc, Michal|Sourkova, Vladimira|Andera, Ladislav|Pintzas, Alexander
PMID: 21738740
Journal: Apoptosis. 2011 Oct;16(10):1042-53.
Title: Silibinin triggers apoptotic signaling pathways and autophagic survival response in human colon adenocarcinoma cells and their derived metastatic cells.
Author: Kauntz, Henriette|Bousserouel, Souad|Gosse, Francine|Raul, Francis
PMID: 21779837
Journal: Oncol Rep. 2011 Nov;26(5):1091-7.
Title: Expression of p53 and DR5 in normal and malignant tissues of colorectal cancer: correlation with advanced stages.
Author: Perraud, Aurelie|Akil, Hussein|Nouaille, Michelle|Petit, Daniel|Labrousse, Francois|Jauberteau, Marie-Odile|Mathonnet, Muriel
PMID: 21805040
Journal: Mol Cancer Ther. 2011 Oct;10(10):1969-81.
Title: 2-methoxy-5-amino-N-hydroxybenzamide sensitizes colon cancer cells to TRAIL-induced apoptosis by regulating death receptor 5 and survivin expression.
Author: Stolfi, Carmine|Caruso, Roberta|Franze, Eleonora|Rizzo, Angelamaria|Rotondi, Angela|Monteleone, Ivan|Fantini, Massimo Claudio|Pallone, Francesco|Monteleone, Giovanni
PMID: 21817114
Journal: Am J Pathol. 2011 Dec;179(6):3032-44.
Title: Coexpression of activated c-Met and death receptor 5 predicts better survival in colorectal carcinoma.
Author: Uddin, Shahab|Hussain, Azhar R|Ahmed, Maqbool|Al-Sanea, Nasser|Abduljabbar, Alaa|Ashari, Luai H|Alhomoud, Samar|Al-Dayel, Fouad|Bavi, Prashant|Al-Kuraya, Khawla S
PMID: 21978492
Journal: J Biol Chem. 2011 Dec 16;286(50):43123-33.
Title: GDP-mannose-4,6-dehydratase (GMDS) deficiency renders colon cancer cells resistant to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor- and CD95-mediated apoptosis by inhibiting complex II formation.
Author: Moriwaki, Kenta|Shinzaki, Shinichiro|Miyoshi, Eiji
PMID: 22027835
Journal: Mol Biol Rep. 2012 Jan;39(1):243-9.
Title: PNAS-4 expression and its relationship to p53 in colorectal cancer.
Author: Zhou, Bin|Yan, Hui|Li, Yuan|Wang, Rong|Chen, Keling|Zhou, Zongguang|Sun, Xiaofeng
PMID: 21556770
Journal: Br J Pharmacol. 2012 Feb;165(3):741-53.
Title: Cardamonin sensitizes tumour cells to TRAIL through ROS- and CHOP-mediated up-regulation of death receptors and down-regulation of survival proteins.
Author: Yadav, Vivek R|Prasad, Sahdeo|Aggarwal, Bharat B
PMID: 21797841
Journal: Oncogene. 2012 Apr 26;31(17):2210-21.
Title: Key role of ATF3 in p53-dependent DR5 induction upon DNA damage of human colon cancer cells.
Author: Taketani, K|Kawauchi, J|Tanaka-Okamoto, M|Ishizaki, H|Tanaka, Y|Sakai, T|Miyoshi, J|Maehara, Y|Kitajima, S
PMID: 21927023
Journal: Mol Ther. 2012 Jan;20(1):46-53.
Title: 2A peptide-based, lentivirus-mediated anti-death receptor 5 chimeric antibody expression prevents tumor growth in nude mice.
Author: Li, Meng|Wu, Yaomin|Qiu, Yuhe|Yao, Zhenyu|Liu, Shilian|Liu, Yanxin|Shi, Juan|Zheng, Dexian
PMID: 21934654
Journal: Br J Nutr. 2012 Jun;107(11):1591-602.
Title: Stool-fermented Plantago ovata husk induces apoptosis in colorectal cancer cells independently of molecular phenotype.
Author: Sohn, Vanessa R|Giros, Anna|Xicola, Rosa M|Fluvia, Lourdes|Grzybowski, Mike|Anguera, Anna|Llor, Xavier
PMID: 22018732
Journal: Apoptosis. 2012 Mar;17(3):236-47.
Title: Pleomorphic adenoma gene-like 2 regulates expression of the p53 family member, p73, and induces cell cycle block and apoptosis in human promonocytic U937 cells.
Author: Hanks, Tracey S|Gauss, Katherine A
PMID: 22076304
Journal: J Biol Chem. 2012 Jan 2;287(1):641-9.
Title: Wogonin and related natural flavones overcome tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) protein resistance of tumors by down-regulation of c-FLIP protein and up-regulation of TRAIL receptor 2 expression.
Author: Ding, Jie|Polier, Gernot|Kohler, Rebecca|Giaisi, Marco|Krammer, Peter H|Li-Weber, Min
PMID: 22086925
Journal: J Cell Biochem. 2012 May;113(5):1547-58.
Title: Hyperthermia-enhanced TRAIL- and mapatumumab-induced apoptotic death is mediated through mitochondria in human colon cancer cells.
Author: Song, Xinxin|Kim, Han-Cheon|Kim, Seog-Young|Basse, Per|Park, Bae-Hang|Lee, Byeong-Chel|Lee, Yong J
PMID: 22174016
Journal: Cancer Sci. 2012 Jan;103(1):150-3.
Title: First clinical trial of cancer vaccine therapy with artificially synthesized helper/ killer-hybrid epitope long peptide of MAGE-A4 cancer antigen.
Author: Takahashi, Norihiko|Ohkuri, Takayuki|Homma, Shigenori|Ohtake, Junya|Wakita, Daiko|Togashi, Yuji|Kitamura, Hidemitsu|Todo, Satoru|Nishimura, Takashi
PMID: 22221328
Journal: Phytother Res. 2012 Oct;26(10):1541-6.
Title: 3-O-acetyloleanolic acid induces apoptosis in human colon carcinoma HCT-116 cells.
Author: Yoo, Ki Hyun|Park, Jong-Hwa|Cui, En Ji|Kim, Kyung Il|Kim, Joo Yun|Kim, Jiyoung|Hong, Seong Gil|Baek, Nam In|Chung, In Sik
PMID: 22359244
Journal: PLoS One. 2012;7(2):e31762.
Title: Sub-lethal irradiation of human colorectal tumor cells imparts enhanced and sustained susceptibility to multiple death receptor signaling pathways.
Author: Ifeadi, Victoria|Garnett-Benson, Charlie
PMID: 22389673
Journal: Oncol Rep. 2012 Jun;27(6):2023-30.
Title: Docosahexaenoic acid sensitizes colon cancer cells to sulindac sulfide-induced apoptosis.
Author: Lim, Soo-Jeong|Lee, Eunmyong|Lee, Eun-Hye|Kim, Soo-Yeon|Cha, Jun Hyung|Choi, Hwanho|Park, Wanseo|Choi, Hyeon Kyeom|Ko, Seong-Hee|Kim, So Hee
PMID: 22395735
Journal: Gastroenterology. 2012 Jul;143(1):155-65.e8.
Title: An RNA aptamer that binds carcinoembryonic antigen inhibits hepatic metastasis of colon cancer cells in mice.
Author: Lee, Young Ju|Han, Seung Ryul|Kim, Nam Yeon|Lee, Soo-Han|Jeong, Jin-Sook|Lee, Seong-Wook
PMID: 22465431
Journal: Clin Dev Immunol. 2012;2012:238924.
Title: Improved activation toward primary colorectal cancer cells by antigen-specific targeting autologous cytokine-induced killer cells.
Author: Schlimper, Claudia|Hombach, Andreas A|Abken, Hinrich|Schmidt-Wolf, Ingo G H
PMID: 22481963
Journal: Cell Death Dis. 2012 Apr 12;3:e295.
Title: Superior antitumoral activity of dimerized targeted single-chain TRAIL fusion proteins under retention of tumor selectivity.
Author: Siegemund, M|Pollak, N|Seifert, O|Wahl, K|Hanak, K|Vogel, A|Nussler, A K|Gottsch, D|Munkel, S|Bantel, H|Kontermann, R E|Pfizenmaier, K
PMID: 22495350
Journal: Apoptosis. 2012 Aug;17(8):797-809.
Title: The flavonolignan silibinin potentiates TRAIL-induced apoptosis in human colon adenocarcinoma and in derived TRAIL-resistant metastatic cells.
Author: Kauntz, Henriette|Bousserouel, Souad|Gosse, Francine|Raul, Francis
PMID: 22555452
Journal: BMC Cancer. 2012 Jun 8;12:228.
Title: Snake venom toxin from Vipera lebetina turanica induces apoptosis of colon cancer cells via upregulation of ROS- and JNK-mediated death receptor expression.
Author: Park, Mi Hee|Jo, MiRan|Won, Dohee|Song, Ho Sueb|Han, Sang Bae|Song, Min Jong|Hong, Jin Tae
PMID: 22681760
Journal: Cell Cycle. 2012 Sep 1;11(17):3312-23.
Title: Mitomycin C potentiates TRAIL-induced apoptosis through p53-independent upregulation of death receptors: evidence for the role of c-Jun N-terminal kinase activation.
Author: Cheng, Hairong|Hong, Bo|Zhou, Lanlan|Allen, Joshua E|Tai, Guihua|Humphreys, Robin|Dicker, David T|Liu, Yingqiu Y|El-Deiry, Wafik S
PMID: 22895172
Journal: Free Radic Biol Med. 2012 Nov 15;53(10):1977-87.
Title: Capsazepine, a TRPV1 antagonist, sensitizes colorectal cancer cells to apoptosis by TRAIL through ROS-JNK-CHOP-mediated upregulation of death receptors.
Author: Sung, Bokyung|Prasad, Sahdeo|Ravindran, Jayaraj|Yadav, Vivek R|Aggarwal, Bharat B
PMID: 22922338
Journal: Int J Mol Med. 2012 Nov;30(5):1087-94.
Title: The synergistic effects of low-dose irinotecan and TRAIL on TRAIL-resistant HT-29 colon carcinoma in vitro and in vivo.
Author: Zhu, Hong|Zhao, Fen|Yu, Shuijing|He, Jianping|Deng, Licong|Yi, Cheng|Huang, Ying
PMID: 22922573
Journal: Gan To Kagaku Ryoho. 2012 Nov;39(12):1812-4.
Title: [Hepatic intra-arterial infusion of biological response modifier (BRM)-activated killer immune lymphocytes to treat liver cancer].
Author: Ebina, Takusaburo
PMID: 23267895
Journal: J Cell Physiol. 2013 Apr;228(4):764-72.
Title: Inhibition of PRC2 histone methyltransferase activity increases TRAIL-mediated apoptosis sensitivity in human colon cancer cells.
Author: Benoit, Yannick D|Laursen, Kristian B|Witherspoon, Mavee S|Lipkin, Steven M|Gudas, Lorraine J
PMID: 23001792
Journal: Oncol Rep. 2013 Feb;29(2):474-80.
Title: Casticin, a flavonoid, potentiates TRAIL-induced apoptosis through modulation of anti-apoptotic proteins and death receptor 5 in colon cancer cells.
Author: Tang, San-Yuan|Zhong, Mei-Zuo|Yuan, Guang-Jin|Hou, Su-Ping|Yin, Lei-Lan|Jiang, Hao|Yu, Zheng-Upsilonang
PMID: 23135489
Journal: Expert Opin Investig Drugs. 2013 Jan;22(1):35-47.
Title: Lung cancer chemoprevention: difficulties, promise and potential agents?
Author: Dragnev, Konstantine|You, Ming|Wang, Yian|Lubet, Ronald
PMID: 23167766
Journal: Biomacromolecules. 2013 Feb 11;14(2):302-10.
Title: Enhanced antitumor activity of the photosensitizer meso-Tetra(N-methyl-4-pyridyl) porphine tetra tosylate through encapsulation in antibody-targeted chitosan/alginate nanoparticles.
Author: Abdelghany, Sharif M|Schmid, Daniela|Deacon, Jill|Jaworski, Jakub|Fay, Francois|McLaughlin, Kirsty M|Gormley, Julie A|Burrows, James F|Longley, Daniel B|Donnelly, Ryan F|Scott, Christopher J
PMID: 23327610
Journal: Cell Death Dis. 2013 Feb 21;4:e503.
Title: Delivery of sTRAIL variants by MSCs in combination with cytotoxic drug treatment leads to p53-independent enhanced antitumor effects.
Author: Yu, R|Deedigan, L|Albarenque, S M|Mohr, A|Zwacka, R M
PMID: 23429289
Journal: Apoptosis. 2013 Jun;18(6):713-26.
Title: Upregulation of DR5 receptor by the diaminothiazole DAT1 [4-amino-5-benzoyl-2-(4-methoxy phenyl amino) thiazole] triggers an independent extrinsic pathway of apoptosis in colon cancer cells with compromised pro and antiapoptotic proteins.
Author: Thomas, Sannu A|Vasudevan, Smreti|Thamkachy, Reshma|Lekshmi, Swathi U|Santhoshkumar, Thankayyan R|Rajasekharan, Kallikat N|Sengupta, Suparna
PMID: 23435998
Journal: BMC Public Health. 2013 May 20;13:487.
Title: Study protocol for "Moving Bright, Eating Smart"- A phase 2 clinical trial on the acceptability and feasibility of a diet and physical activity intervention to prevent recurrence in colorectal cancer survivors.
Author: Ho, Judy W C|Lee, Antoinette M|Macfarlane, Duncan J|Fong, Daniel Y T|Leung, Sharron|Cerin, Ester|Chan, Wynnie Y Y|Leung, Ivy P F|Lam, Sharon H S|Taylor, Aliki J|Cheng, Kar-keung
PMID: 23688320
Journal: Free Radic Biol Med. 2013 Oct;63:280-90.
Title: Aldose reductase inhibition enhances TRAIL-induced human colon cancer cell apoptosis through AKT/FOXO3a-dependent upregulation of death receptors.
Author: Shoeb, Mohammad|Ramana, Kota V|Srivastava, Satish K
PMID: 23732517
Journal: Acta Biochim Biophys Sin (Shanghai). 2013 Sep;45(9):709-19.
Title: 5-lipoxygenase antagonist therapy: a new approach towards targeted cancer chemotherapy.
Author: Bishayee, Kausik|Khuda-Bukhsh, Anisur Rahman
PMID: 23752617
Journal: Int J Oncol. 2013 Aug;43(2):394-404.
Title: Methanolic extract of white asparagus shoots activates TRAIL apoptotic death pathway in human cancer cells and inhibits colon carcinogenesis in a preclinical model.
Author: Bousserouel, Souad|Le Grandois, Julie|Gosse, Francine|Werner, Dalal|Barth, Stephan W|Marchioni, Eric|Marescaux, Jacques|Raul, Francis
PMID: 23754197
Journal: PLoS One. 2013 Jun 6;8(6):e65145.
Title: Chemotherapy sensitizes colon cancer initiating cells to Vgamma9Vdelta2 T cell-mediated cytotoxicity.
Author: Todaro, Matilde|Orlando, Valentina|Cicero, Giuseppe|Caccamo, Nadia|Meraviglia, Serena|Stassi, Giorgio|Dieli, Francesco
PMID: 23762301
Journal: In Vivo. 2013 Jul-Aug;27(4):431-42.
Title: Targeting cancer with a bi-functional peptide: in vitro and in vivo results.
Author: Meschenmoser, Karoline|Kim, Young|Franken, Sebastian|Nowak, Michael|Feldmann, Georg|Bendas, Gerd|Wolfgarten, Matthias|Messmer, Davorka|Schmidt-Wolf, Ingo G H
PMID: 23812212
Journal: Cancer Immunol Immunother. 2013 Oct;62(10):1629-35.
Title: Efficacy of postoperative adjuvant transfusion of cytokine-induced killer cells combined with chemotherapy in patients with colorectal cancer.
Author: Zhu, Yanjuan|Zhang, Haibo|Li, Yong|Bai, Jianping|Liu, Lirong|Liu, Yihong|Qu, Yanchun|Qu, Xin
PMID: 23974720
Journal: Oncol Rep. 2013 Nov;30(5):2379-84.
Title: Ibuprofen enhances TRAIL-induced apoptosis through DR5 upregulation.
Author: Todo, Momoko|Horinaka, Mano|Tomosugi, Mitsuhiro|Tanaka, Ryoichi|Ikawa, Haruna|Sowa, Yoshihiro|Ishikawa, Hideki|Fujiwara, Hitoshi|Otsuji, Eigo|Sakai, Toshiyuki
PMID: 24002210
Journal: Clin Cancer Res. 2013 Nov 1;19(21):5984-93.
Title: Molecular imaging of death receptor 5 occupancy and saturation kinetics in vivo by humanized monoclonal antibody CS-1008.
Author: Burvenich, Ingrid J G|Lee, Fook T|Cartwright, Glenn A|O'Keefe, Graeme J|Makris, Dahna|Cao, Diana|Gong, Sylvia|Chueh, Anderly C|Mariadason, John M|Brechbiel, Martin W|Beckman, Robert A|Fujiwara, Kosaku|von Roemeling, Reinhard|Scott, Andrew M
PMID: 24045184
Journal: Cancer Sci. 2013 Dec;104(12):1632-9.
Title: Amurensin G enhances the susceptibility to tumor necrosis factor-related apoptosis-inducing ligand-mediated cytotoxicity of cancer stem-like cells of HCT-15 cells.
Author: Lee, Su-Hoon|Kim, Mi-Ju|Kim, Dong-Wan|Kang, Chi-Dug|Kim, Sun-Hee
PMID: 24118446
Journal: Cancer. 2013 Dec 15;119(24):4290-8.
Title: TRAIL receptor agonist conatumumab with modified FOLFOX6 plus bevacizumab for first-line treatment of metastatic colorectal cancer: A randomized phase 1b/2 trial.
Author: Fuchs, Charles S|Fakih, Marwan|Schwartzberg, Lee|Cohn, Allen L|Yee, Lorrin|Dreisbach, Luke|Kozloff, Mark F|Hei, Yong-jiang|Galimi, Francesco|Pan, Yang|Haddad, Vincent|Hsu, Cheng-Pang|Sabin, Antony|Saltz, Leonard
PMID: 24122767
Journal: Asian Pac J Cancer Prev. 2013;14(10):6035-40.
Title: Comparison of population based cancer incidence rates among Circassians, Chechans and Arabs in Jordan (1996-2005).
Author: Fathallah, Raja Mohd-Talal|Dajani, Rana
PMID: 24289621
Journal: Oncol Res. 2013;21(3):155-64.
Title: The sirtuin inhibitor tenovin-6 upregulates death receptor 5 and enhances cytotoxic effects of 5-fluorouracil and oxaliplatin in colon cancer cells.
Author: Ueno, Takunori|Endo, Shinji|Saito, Rie|Hirose, Mitsuaki|Hirai, Sachiko|Suzuki, Hideo|Yamato, Kenji|Hyodo, Ichinosuke
PMID: 24512730
Journal: Cancer Treat Rev. 2014 May;40(4):485-94.
Title: The impact of personalized medicine on survival: comparisons of results in metastatic breast, colorectal and non-small-cell lung cancers.
Author: Rossi, Antonio|Torri, Valter|Garassino, Marina Chiara|Porcu, Luca|Galetta, Domenico
PMID: 24112813
Journal: Oncol Rep. 2014 Feb;31(2):947-54.
Title: Peroxisome proliferator-activated receptor gamma ligand troglitazone and TRAIL synergistically induce apoptosis.
Author: Koyama, Makoto|Sowa, Yoshihiro|Horinaka, Mano|Goda, Ahmed E|Fujiwara, Jun|Sakai, Toshiyuki
PMID: 24276615
Journal: Carcinogenesis. 2014 May;35(5):1092-9.
Title: Regulation of TRAIL receptor expression by beta-catenin in colorectal tumours.
Author: Jalving, M|Heijink, D M|Koornstra, J J|Boersma-van Ek, W|Zwart, N|Wesseling, J|Sluiter, W J|de Vries, E G E|Kleibeuker, J H|de Jong, S
PMID: 24379239
Journal: Biochem Biophys Res Commun. 2014 Mar 7;445(2):320-6.
Title: Role of ATF3 in synergistic cancer cell killing by a combination of HDAC inhibitors and agonistic anti-DR5 antibody through ER stress in human colon cancer cells.
Author: Liu, Jia|Edagawa, Makoto|Goshima, Hiroto|Inoue, Makoto|Yagita, Hideo|Liu, Zhonghui|Kitajima, Shigetaka
PMID: 24530917
Journal: Oncol Lett. 2014 May;7(5):1728-1732.
Title: Laminarin-induced apoptosis in human colon cancer LoVo cells.
Author: Ji, Chen-Feng|Ji, Yu-Bin
PMID: 24765209
Journal: Cancer Res. 2014 Jun 1;74(11):2913-21.
Title: Projecting cancer incidence and deaths to 2030: the unexpected burden of thyroid, liver, and pancreas cancers in the United States.
Author: Rahib, Lola|Smith, Benjamin D|Aizenberg, Rhonda|Rosenzweig, Allison B|Fleshman, Julie M|Matrisian, Lynn M
PMID: 24840647
Journal: Biomed Pharmacother. 2014 Jun;68(5):551-6.
Title: Modification of chemokine receptor expression to enhance levels of trafficking receptors on autologous cytokine-induced killer cells derived from patients with colorectal cancer.
Author: Wang, Dan|Li, Jing|Liu, Jin-Yan|Li, Feng|Wang, Li-Ping|Huang, Lan|Li, Jie-Yao|Chen, Xin-Feng|Liu, Jin-Bo|Wu, Chang-Cai|Yuan, Wei-Tang|Wang, Gui-Xian|Song, Jun-Min|Yue, Dong-Li|Zhang, Zhen|Ping, Yu|Wang, Rui-Rui|Zhang, Jian-Ying|Zhang, Yi
PMID: 24855035
Journal: J Cell Biochem. 2014 Nov;115(11):1888-99.
Title: Expression of survivin and p53 modulates honokiol-induced apoptosis in colorectal cancer cells.
Author: Lai, Ying-Jiun|Lin, Chien-I|Wang, Chia-Lin|Chao, Jui-I
PMID: 24905183
Journal: Food Chem Toxicol. 2014 Sep;71:51-9.
Title: Ilimaquinone induces death receptor expression and sensitizes human colon cancer cells to TRAIL-induced apoptosis through activation of ROS-ERK/p38 MAPK-CHOP signaling pathways.
Author: Do, Minh Truong|Na, MinKyun|Kim, Hyung Gyun|Khanal, Tilak|Choi, Jae Ho|Jin, Sun Woo|Oh, Seok Hoon|Hwang, In Hyun|Chung, Young Chul|Kim, Hee Suk|Jeong, Tae Cheon|Jeong, Hye Gwang
PMID: 24930757
Journal: J Biol Chem. 2014 Aug 1;289(31):21544-61.
Title: Role of activating transcription factor 3 (ATF3) in endoplasmic reticulum (ER) stress-induced sensitization of p53-deficient human colon cancer cells to tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis through up-re
Author: Edagawa, Makoto|Kawauchi, Junya|Hirata, Manabu|Goshima, Hiroto|Inoue, Makoto|Okamoto, Tatsuro|Murakami, Akira|Maehara, Yoshihiko|Kitajima, Shigetaka
PMID: 24939851
Journal: Sci Rep. 2014 Aug 8;4:6000.
Title: Myeloid zinc finger 1 mediates sulindac sulfide-induced upregulation of death receptor 5 of human colon cancer cells.
Author: Horinaka, Mano|Yoshida, Tatsushi|Tomosugi, Mitsuhiro|Yasuda, Shusuke|Sowa, Yoshihiro|Sakai, Toshiyuki
PMID: 25102912
Journal: J Ethnopharmacol. 2014 Oct 28;156:277-89.
Title: Annona muricata leaves induce G(1) cell cycle arrest and apoptosis through mitochondria-mediated pathway in human HCT-116 and HT-29 colon cancer cells.
Author: Zorofchian Moghadamtousi, Soheil|Karimian, Hamed|Rouhollahi, Elham|Paydar, Mohammadjavad|Fadaeinasab, Mehran|Abdul Kadir, Habsah
PMID: 25195082
Journal: Mol Ther. 2014 Dec;22(12):2083-92.
Title: Efficient drug delivery and induction of apoptosis in colorectal tumors using a death receptor 5-targeted nanomedicine.
Author: Schmid, Daniela|Fay, Francois|Small, Donna M|Jaworski, Jakub|Riley, Joel S|Tegazzini, Diana|Fenning, Cathy|Jones, David S|Johnston, Patrick G|Longley, Daniel B|Scott, Christopher J
PMID: 25200008
Journal: Biomed Res Int. 2014;2014:214727.
Title: Retrospective comparative study of the effects of dendritic cell vaccine and cytokine-induced killer cell immunotherapy with that of chemotherapy alone and in combination for colorectal cancer.
Author: Niu, Jingxiu|Ren, Yanjie|Zhang, Tianyu|Yang, Xuejing|Zhu, Wei|Zhu, Hui|Li, Jing|Li, Jiali|Pang, Yan
PMID: 25210706
Journal: World J Gastroenterol. 2014 Oct 14;20(38):13820-32.
Title: Virtual gastrointestinal colonoscopy in combination with large bowel endoscopy: clinical application.
Author: He, Qing|Rao, Ting|Guan, Yong-Song
PMID: 25320519
Journal: MAbs. 2014;6(6):1560-70.
Title: Multivalent nanobodies targeting death receptor 5 elicit superior tumor cell killing through efficient caspase induction.
Author: Huet, Heather A|Growney, Joseph D|Johnson, Jennifer A|Li, Jing|Bilic, Sanela|Ostrom, Lance|Zafari, Mohammad|Kowal, Colleen|Yang, Guizhi|Royo, Axelle|Jensen, Michael|Dombrecht, Bruno|Meerschaert, Kris R A|Kolkman, Joost A|Cromie, Karen D|Mosher, Rebecca|Ga
PMID: 25484045
Journal: Oncogene. 2015 Feb 26;34(9):1150-9.
Title: Functional characterization of the tumor-suppressor MARCKS in colorectal cancer and its association with survival.
Author: Bickeboller, M|Tagscherer, K E|Kloor, M|Jansen, L|Chang-Claude, J|Brenner, H|Hoffmeister, M|Toth, C|Schirmacher, P|Roth, W|Blaker, H
PMID: 24662837
Journal: Target Oncol. 2015 Mar;10(1):65-76.
Title: Anticancer activity of the type I insulin-like growth factor receptor antagonist, ganitumab, in combination with the death receptor 5 agonist, conatumumab.
Author: Tabernero, Josep|Chawla, Sant P|Kindler, Hedy|Reckamp, Karen|Chiorean, E Gabriela|Azad, Nilofer S|Lockhart, A Craig|Hsu, Cheng-Pang|Baker, Nigel F|Galimi, Francesco|Beltran, Pedro|Baselga, Jose
PMID: 24816908
Journal: Exp Cell Res. 2015 Jan 15;330(2):451-9.
Title: COX-2- and endoplasmic reticulum stress-independent induction of ULBP-1 and enhancement of sensitivity to NK cell-mediated cytotoxicity by celecoxib in colon cancer cells.
Author: Kim, So-Jung|Ha, Ga-Hee|Bae, Jae-Ho|Kim, Ga Rim|Son, Cheol-Hun|Park, You-Soo|Yang, Kwangmo|Oh, Sae-Ock|Kim, Sun-Hee|Kang, Chi-Dug
PMID: 25218028
Journal: Acta Biomater. 2015 Jan;12:174-182.
Title: Hyaluronic acid-tumor necrosis factor-related apoptosis-inducing ligand conjugate for targeted treatment of liver fibrosis.
Author: Yang, Jeong-A|Kong, Won Ho|Sung, Dong Kyung|Kim, Hyemin|Kim, Tae Hyung|Lee, Kang Choon|Hahn, Sei Kwang
PMID: 25305513
Journal: Int J Oncol. 2015 Mar;46(3):1121-30.
Title: Parthenolide enhances sensitivity of colorectal cancer cells to TRAIL by inducing death receptor 5 and promotes TRAIL-induced apoptosis.
Author: Kim, Se-Lim|Liu, Yu-Chuan|Park, Young Ran|Seo, Seung Young|Kim, Seong Hun|Kim, In Hee|Lee, Seung Ok|Lee, Soo Teik|Kim, Dae-Ghon|Kim, Sang-Wook
PMID: 25502339
Journal: Oncol Rep. 2015 Apr;33(4):1947-55.
Title: Evaluation of preventive and therapeutic activity of novel non-steroidal anti-inflammatory drug, CG100649, in colon cancer: Increased expression of TNF-related apoptosis-inducing ligand receptors enhance the apoptotic response to combination treatment wit
Author: Woo, Jong Kyu|Kang, Ju-Hee|Jang, Yeong-Su|Ro, Seonggu|Cho, Joong Myung|Kim, Hwan-Mook|Lee, Sang-Jin|Oh, Seung Hyun
PMID: 25672292
Journal: J Pharmacol Sci. 2015 Jan;127(1):83-91.
Title: TRAIL pathway is associated with inhibition of colon cancer by protopanaxadiol.
Author: Zhang, Zhiyu|Li, Zejuan|Wu, Xiaohui|Zhang, Chun-Feng|Calway, Tyler|He, Tong-Chuan|Du, Wei|Chen, Jianjun|Wang, Chong-Zhi|Yuan, Chun-Su
PMID: 25704023
Journal: Oncol Lett. 2015 Apr;9(4):1549-1556.
Title: Cytokine-induced killer cells co-cultured with dendritic cells loaded with the protein lysate produced by radiofrequency ablation induce a specific antitumor response.
Author: Shan, Chan-Chan|Shi, Liang-Rong|Ding, Mei-Qian|Zhu, Yi-Bei|Li, Xiao-Dong|Xu, Bin|Jiang, Jing-Ting|Wu, Chang-Ping
PMID: 25788999
Journal: Oncol Lett. 2015 Apr;9(4):1641-1646.
Title: Metastatic colon cancer cell populations contain more cancer stem-like cells with a higher susceptibility to natural killer cell-mediated lysis compared with primary colon cancer cells.
Author: Kim, Ga Rim|Ha, Ga-Hee|Bae, Jae-Ho|Oh, Sae-Ock|Kim, Sun-Hee|Kang, Chi-Dug
PMID: 25789015
Journal: Pathol Res Pract. 2015 Jun;211(6):444-8.
Title: Downregulation of external death receptor genes FAS and DR5 in colorectal cancer samples positive for human papillomavirus infection.
Author: Karbasi, Ashraf|Borhani, Nasim|Daliri, Karim|Kazemi, Bahram|Manoochehri, Mehdi
PMID: 25795228
Journal: Oncotarget. 2015 May 10;6(13):11614-26.
Title: FTY720 enhances TRAIL-mediated apoptosis by up-regulating DR5 and down-regulating Mcl-1 in cancer cells.
Author: Woo, Seon Min|Seo, Bo Ram|Min, Kyoung-jin|Kwon, Taeg Kyu
PMID: 25843953
Journal: Tumour Biol. 2015 Nov;36(11):8819-29.
Title: Shogaol overcomes TRAIL resistance in colon cancer cells via inhibiting of survivin.
Author: Hwang, Jung Soon|Lee, Hai-Chon|Oh, Sang Cheul|Lee, Dae-Hee|Kwon, Ki Han
PMID: 26063410
Journal: J Immunol. 2015 Aug 15;195(4):1868-82.
Title: H3K9 Trimethylation Silences Fas Expression To Confer Colon Carcinoma Immune Escape and 5-Fluorouracil Chemoresistance.
Author: Paschall, Amy V|Yang, Dafeng|Lu, Chunwan|Choi, Jeong-Hyeon|Li, Xia|Liu, Feiyan|Figueroa, Mario|Oberlies, Nicholas H|Pearce, Cedric|Bollag, Wendy B|Nayak-Kapoor, Asha|Liu, Kebin
PMID: 26136424
Journal: Acta Pharmacol Sin. 2015 Sep;36(9):1074-84.
Title: New benzimidazole acridine derivative induces human colon cancer cell apoptosis in vitro via the ROS-JNK signaling pathway.
Author: Chen, Kang|Chu, Bi-zhu|Liu, Feng|Li, Bin|Gao, Chun-mei|Li, Lu-lu|Sun, Qin-sheng|Shen, Zhi-fa|Jiang, Yu-yang
PMID: 26235743
Journal: Oncotarget. 2015 Sep 22;6(28):25828-42.
Title: Understanding of tolerance in TRAIL-induced apoptosis and cancelation of its machinery by alpha-mangostin, a xanthone derivative.
Author: Kumazaki, Minami|Shinohara, Haruka|Taniguchi, Kohei|Ueda, Hiroshi|Nishi, Mayuko|Ryo, Akihide|Akao, Yukihiro
PMID: 26304927
Journal: J Control Release. 2015 Dec 28;220(Pt B):671-81.
Title: Delivery of tumor-homing TRAIL sensitizer with long-acting TRAIL as a therapy for TRAIL-resistant tumors.
Author: Oh, Yumin|Swierczewska, Magdalena|Kim, Tae Hyung|Lim, Sung Mook|Eom, Ha Na|Park, Jae Hyung|Na, Dong Hee|Kim, Kwangmeyung|Lee, Kang Choon|Pomper, Martin G|Lee, Seulki
PMID: 26381901
Journal: Anticancer Res. 2015 Oct;35(10):5407-16.
Title: Synthetic Bichalcone TSWU-BR23 Induces Apoptosis of Human Colon Cancer HT-29 Cells by p53-Mediated Mitochondrial Oligomerization of BAX/BAK and Lipid Raft Localization of CD95/FADD.
Author: Lin, Meng-Liang|Chen, Shih-Shun|Wu, Tian-Shung
PMID: 26408703
Journal: J Health Dispar Res Pract. 2015 Fall;8(3):133-156.
Title: Factors Associated with Colorectal Cancer Screening among Younger African American Men: A Systematic Review.
Author: Rogers, Charles R|Goodson, Patricia|Foster, Margaret J
PMID: 26435888
Journal: Int J Oncol. 2015 Dec;47(6):2264-75.
Title: Radiation-induced modulation of immunogenic genes in tumor cells is regulated by both histone deacetylases and DNA methyltransferases.
Author: Cacan, Ercan|Greer, Susanna F|Garnett-Benson, Charlie
PMID: 26458736
Journal: Mol Med Rep. 2015 Dec;12(6):8062-70.
Title: Anti-cancer effects of 2-oxoquinoline derivatives on the HCT116 and LoVo human colon cancer cell lines.
Author: Fang, Feng-Qi|Guo, Hui-Shu|Zhang, Jie|Ban, Li-Ying|Liu, Ji-Wei|Yu, Pei-Yao
PMID: 26498992
Journal: Int J Oncol. 2015 Dec;47(6):2188-96.
Title: Goniothalamin enhances TRAIL-induced apoptosis in colorectal cancer cells through DR5 upregulation and cFLIP downregulation.
Author: Sophonnithiprasert, Thanet|Nilwarangkoon, Sirinun|Nakamura, Yukio|Watanapokasin, Ramida
PMID: 26499766
Journal: Int J Mol Sci. 2015 Dec 21;16(12):30405-21.
Title: Combination Treatment with Sublethal Ionizing Radiation and the Proteasome Inhibitor, Bortezomib, Enhances Death-Receptor Mediated Apoptosis and Anti-Tumor Immune Attack.
Author: Cacan, Ercan|Spring, Alexander M|Kumari, Anita|Greer, Susanna F|Garnett-Benson, Charlie
PMID: 26703577
Journal: Yao Xue Xue Bao. 2015 Oct;50(10):1252-7.
Title: [Sensitization of human colon cancer HT-29 cells to TRAIL-induced apoptosis by gambognic acid].
Author: Ye, Ji-lin|Yu, You-jiang|Wu, Ai-lian|Wang, Dong-yan|Liu, Yong-chun|Liu, Yan-qing
PMID: 26837170
Journal: Oncogene. 2016 Jan 14;35(2):148-57.
Title: mTOR inhibitors induce apoptosis in colon cancer cells via CHOP-dependent DR5 induction on 4E-BP1 dephosphorylation.
Author: He, K|Zheng, X|Li, M|Zhang, L|Yu, J
PMID: 25867072
Journal: Oncotarget. 2016 Feb 9;7(6):7161-78.
Title: The probiotic Propionibacterium freudenreichii as a new adjuvant for TRAIL-based therapy in colorectal cancer.
Author: Cousin, Fabien J|Jouan-Lanhouet, Sandrine|Theret, Nathalie|Brenner, Catherine|Jouan, Elodie|Le Moigne-Muller, Gwenaelle|Dimanche-Boitrel, Marie-Therese|Jan, Gwenael
PMID: 26771233
Journal: Oncotarget. 2016 Jan 26;7(4):3709-25.
Title: Cooperative TRAIL production mediates IFNalpha/Smac mimetic-induced cell death in TNFalpha-resistant solid cancer cells.
Author: Roesler, Stefanie|Eckhardt, Ines|Wolf, Sebastian|Fulda, Simone
PMID: 26788912
Journal: PLoS One. 2016 Feb 9;11(2):e0148775.
Title: Flavokawain C Inhibits Cell Cycle and Promotes Apoptosis, Associated with Endoplasmic Reticulum Stress and Regulation of MAPKs and Akt Signaling Pathways in HCT 116 Human Colon Carcinoma Cells.
Author: Phang, Chung-Weng|Karsani, Saiful Anuar|Sethi, Gautam|Abd Malek, Sri Nurestri
PMID: 26859847
Journal: Oncol Lett. 2016 Feb;11(2):1371-1374.
Title: Effects of CIK on hypoxia inducible factor-1alpha and T-cell subsets on colon 26 cancer xenograft mice.
Author: Zhang, Hongzhen|Guo, Mingli|Chen, Hongyao|Zhang, Ying|He, Li Ya
PMID: 26893745
Journal: Cancer. 2016 Jun 1;122(11):1689-96.
Title: Whole-exome sequencing of duodenal adenocarcinoma identifies recurrent Wnt/beta-catenin signaling pathway mutations.
Author: Yuan, Wei|Zhang, Zhou|Dai, Binghua|Wei, Qing|Liu, Jinjin|Liu, Yuzhen|Liu, Yun|He, Lin|Zhou, Daizhan
PMID: 26998897
Journal: Biochem Biophys Res Commun. 2016 Apr 29;473(2):586-92.
Title: Bakuchiol sensitizes cancer cells to TRAIL through ROS- and JNK-mediated upregulation of death receptors and downregulation of survival proteins.
Author: Park, Mi Hee|Kim, Jong Han|Chung, Young-Ho|Lee, Seung Ho
PMID: 27033605
Journal: Mol Med Rep. 2016 Jun;13(6):4681-8.
Title: Apoptotic effects of extract from Cnidium monnieri (L.) Cusson by adenosine monosphosphate-activated protein kinase-independent pathway in HCT116 colon cancer cells.
Author: Lim, Eun Gyeong|Kim, Guen Tae|Lee, Se Hee|Kim, Sang-Yong|Kim, Young Min
PMID: 27082059
Journal: J Cell Biochem. 2016 Dec;117(12):2875-2885.
Title: Resistance to 3-HTMC-Induced Apoptosis Through Activation of PI3K/Akt, MEK/ERK, and p38/COX-2/PGE2 Pathways in Human HT-29 and HCT116 Colorectal Cancer Cells.
Author: Semaan, Josiane|Pinon, Aline|Rioux, Benjamin|Hassan, Lama|Limami, Youness|Pouget, Christelle|Fagnere, Catherine|Sol, Vincent|Diab-Assaf, Mona|Simon, Alain|Liagre, Bertrand
PMID: 27192488
Journal: Oncol Rep. 2016 Jul;36(1):205-14.
Title: Hwang-Heuk-San induces apoptosis in HCT116 human colorectal cancer cells through the ROS-mediated activation of caspases and the inactivation of the PI3K/Akt signaling pathway.
Author: Lee, Moon Hee|Hong, Su-Hyun|Park, Cheol|Kim, Gi-Young|Leem, Sun-Hee|Choi, Sung Hyun|Keum, Young-Sam|Hyun, Jin Won|Kwon, Taeg Kyu|Hong, Sang Hoon|Choi, Yung Hyun
PMID: 27221553
Journal: Drug Deliv. 2016 Nov;23(9):3505-3519.
Title: Improved anti-tumor activity of oxaliplatin by encapsulating in anti-DR5 targeted gold nanoparticles.
Author: Tummala, Shashank|Kumar, M N Satish|Pindiprolu, Sai Kiran
PMID: 27295176
Journal: Cell Death Dis. 2016 Aug 11;7(8):e2334.
Title: Ginsenoside compound K sensitizes human colon cancer cells to TRAIL-induced apoptosis via autophagy-dependent and -independent DR5 upregulation.
Author: Chen, Lei|Meng, Yue|Sun, Qi|Zhang, Zhongyu|Guo, Xiaoqing|Sheng, Xiaotong|Tai, Guihua|Cheng, Hairong|Zhou, Yifa
PMID: 27512955
Journal: Biochem Biophys Res Commun. 2016 Sep 30;478(4):1515-20.
Title: mTOR inhibition sensitizes ONC201-induced anti-colorectal cancer cell activity.
Author: Jin, Zhe-Zhu|Wang, Wei|Fang, Di-Long|Jin, Yong-Jun
PMID: 27565731
Journal: Apoptosis. 2016 Nov;21(11):1291-1301.
Title: Gefitinib enhances human colon cancer cells to TRAIL-induced apoptosis of via autophagy- and JNK-mediated death receptors upregulation.
Author: Chen, Lei|Meng, Yue|Guo, Xiaoqing|Sheng, Xiaotong|Tai, Guihua|Zhang, Fenglei|Cheng, Hairong|Zhou, Yifa
PMID: 27629794
Journal: Cell Death Discov. 2016 Sep 12;2:16067.
Title: Targeting the metabolic pathway of human colon cancer overcomes resistance to TRAIL-induced apoptosis.
Author: Carr, Ryan M|Qiao, Guilin|Qin, Jianzhong|Jayaraman, Sundararajan|Prabhakar, Bellur S|Maker, Ajay V
PMID: 27648301
Journal: Oncol Lett. 2016 Oct;12(4):2463-2474.
Title: Effect of API-1 and FR180204 on cell proliferation and apoptosis in human DLD-1 and LoVo colorectal cancer cells.
Author: Saglam, Atiye Seda Yar|Alp, Ebru|Elmazoglu, Zubeyir|Menevse, Emine Sevda
PMID: 27698814
Journal: Cancer Lett. 2016 Dec 28;383(2):250-260.
Title: High-order TRAIL oligomer formation in TRAIL-coated lipid nanoparticles enhances DR5 cross-linking and increases antitumour effect against colon cancer.
Author: De Miguel, Diego|Gallego-Lleyda, Ana|Ayuso, Jose Maria|Pejenaute-Ochoa, Dolores|Jarauta, Vidal|Marzo, Isabel|Fernandez, Luis J|Ochoa, Ignacio|Conde, Blanca|Anel, Alberto|Martinez-Lostao, Luis
PMID: 27725224
Journal: J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Nov 15;1036-1037:142-148.
Title: An HPLC method associated with a thermodynamic analysis to compare the binding of TRAIL and its nanovectorized form to death receptors DR4 and DR5 and their relationship to cytotoxicity.
Author: Guillaume, Yves Claude|Lethier, Lydie|Andre, Claire
PMID: 27750195
Journal: Sci Rep. 2016 Nov 9;6:36532.
Title: Death receptor 5 (DR5) and a 5-gene apoptotic biomarker panel with significant differential diagnostic potential in colorectal cancer.
Author: Devetzi, Marina|Kosmidou, Vivian|Vlassi, Margarita|Perysinakis, Iraklis|Aggeli, Chrysanthi|Choreftaki, Theodosia|Zografos, Georgios N|Pintzas, Alexander
PMID: 27827395
Journal: Am J Transl Res. 2016 Oct 15;8(10):4233-4241. eCollection 2016.
Title: Novel markers for circulating tumor stem cells in colorectal carcinoma.
Author: Meng, Qinghui|Wu, Weihua|Pei, Tiemin|Li, Long|Tang, Xiaolong|Sun, Haobo
PMID: 27830007
Journal: J Biomed Nanotechnol. 2016 Jul;12(7):1348-73.
Title: Nanoscale Photodynamic Agents for Colorectal Cancer Treatment: A Review.
Author: Yang, Leping|He, Jun|Wen, Yu|Yi, Wenjun|Li, Qinglong|Lin, Liangwu|Miao, Xiongying|Chen, Wei|Xiong, Li
PMID: 29336532
Journal: Anticancer Drugs. 2017 Jan;28(1):66-74.
Title: Tunicamycin enhances human colon cancer cells to TRAIL-induced apoptosis by JNK-CHOP-mediated DR5 upregulation and the inhibition of the EGFR pathway.
Author: Guo, Xiaoqing|Meng, Yue|Sheng, Xiaotong|Guan, Yuan|Zhang, Fenglei|Han, Zhen|Kang, Yuying|Tai, Guihua|Zhou, Yifa|Cheng, Hairong
PMID: 27603596
Journal: Oncol Rep. 2017 Feb;37(2):1132-1140.
Title: Apigenin induces both intrinsic and extrinsic pathways of apoptosis in human colon carcinoma HCT-116 cells.
Author: Wang, Bo|Zhao, Xin-Huai
PMID: 27959417
Journal: Oncotarget. 2017 Feb 7;8(6):9280-9292.
Title: Co-targeting translation and proteasome rapidly kills colon cancer cells with mutant RAS/RAF via ER stress.
Author: Li, Xiangyun|Li, Mei|Ruan, Hang|Qiu, Wei|Xu, Xiang|Zhang, Lin|Yu, Jian
PMID: 28030835
Journal: Indian J Clin Biochem. 2017 Mar;32(1):9-18.
Title: Calcium, a Cell Cycle Commander, Drives Colon Cancer Cell Diffpoptosis.
Author: Abd-Rabou, Ahmed A
PMID: 28149007
Journal: Sci Rep. 2017 Feb 9;7:42176.
Title: Bigelovin triggered apoptosis in colorectal cancer in vitro and in vivo via upregulating death receptor 5 and reactive oxidative species.
Author: Li, Mingyue|Song, Li-Hua|Yue, Grace Gar-Lee|Lee, Julia Kin-Ming|Zhao, Li-Mei|Li, Lin|Zhou, Xunian|Tsui, Stephen Kwok-Wing|Ng, Simon Siu-Man|Fung, Kwok-Pui|Tan, Ning-Hua|Lau, Clara Bik-San
PMID: 28181527
Journal: PLoS One. 2017 Mar 29;12(3):e0174591.
Title: Tetraarsenic hexoxide induces G2/M arrest, apoptosis, and autophagy via PI3K/Akt suppression and p38 MAPK activation in SW620 human colon cancer cells.
Author: Nagappan, Arulkumar|Lee, Won Sup|Yun, Jeong Won|Lu, Jing Nan|Chang, Seong-Hwan|Jeong, Jae-Hoon|Kim, Gon Sup|Jung, Jin-Myung|Hong, Soon Chan
PMID: 28355296
Journal: Oncol Lett. 2017 Mar;13(3):1470-1478.
Title: Anticancer activity of Nelumbo nucifera stamen extract in human colon cancer HCT-116 cells in vitro.
Author: Zhao, Xin|Feng, Xia|Wang, Cun|Peng, Deguang|Zhu, Kai|Song, Jia-Le
PMID: 28454279
Journal: PLoS One. 2017 Aug 2;12(8):e0180541.
Title: Cancer stem cell-related gene expression as a potential biomarker of response for first-in-class imipridone ONC201 in solid tumors.
Author: Prabhu, Varun V|Lulla, Amriti R|Madhukar, Neel S|Ralff, Marie D|Zhao, Dan|Kline, Christina Leah B|Van den Heuvel, A Pieter J|Lev, Avital|Garnett, Mathew J|McDermott, Ultan|Benes, Cyril H|Batchelor, Tracy T|Chi, Andrew S|Elemento, Olivier|Allen, Joshua E|E
PMID: 28767654
Journal: Cancer Biother Radiopharm. 2017 Aug;32(6):221-226.
Title: Effects of Autologous Cytokine-Induced Killer Cells Infusion in Colorectal Cancer Patients: A Prospective Study.
Author: Peng, Hao|Yao, Meng|Fan, Hongwei|Song, Liwei|Sun, Jinwen|Zhou, Zheng|Du, Yunfeng|Lu, Keyu|Li, Tao|Yin, Aiguo|Xu, Jianhua|Wei, Shidong
PMID: 28820635
Journal: Cell Oncol (Dordr). 2017 Dec;40(6):593-607.
Title: TRAIL enhances quinacrine-mediated apoptosis in breast cancer cells through induction of autophagy via modulation of p21 and DR5 interactions.
Author: Das, Sarita|Nayak, Anmada|Siddharth, Sumit|Nayak, Deepika|Narayan, Satya|Kundu, Chanakya Nath
PMID: 28936683
Journal: Cell Death Dis. 2017 Oct 5;8(10):e3087.
Title: Overaccumulation of p53-mediated autophagy protects against betulinic acid-induced apoptotic cell death in colorectal cancer cells.
Author: Wang, Sen|Wang, Kexin|Zhang, Chundong|Zhang, Wanfeng|Xu, Qian|Wang, Yitao|Zhang, Yulin|Li, Yi|Zhang, Ying|Zhu, Huifang|Song, Fangzhou|Lei, Yunlong|Bu, Youquan
PMID: 28981110
Journal: Drug Deliv. 2017 Nov;24(1):1526-1536.
Title: TRAIL and curcumin codelivery nanoparticles enhance TRAIL-induced apoptosis through upregulation of death receptors.
Author: Yang, Xi|Li, Zhaojun|Wu, Qinjie|Chen, Shouchun|Yi, Cheng|Gong, Changyang
PMID: 28994313
Journal: Cell Rep. 2017 Oct 10;21(2):467-481.
Title: Activation of the p53 Transcriptional Program Sensitizes Cancer Cells to Cdk7 Inhibitors.
Author: Kalan, Sampada|Amat, Ramon|Schachter, Miriam Merzel|Kwiatkowski, Nicholas|Abraham, Brian J|Liang, Yanke|Zhang, Tinghu|Olson, Calla M|Larochelle, Stephane|Young, Richard A|Gray, Nathanael S|Fisher, Robert P
PMID: 29020632
Journal: Theranostics. 2017 Sep 20;7(17):4071-4086.
Title: Transforming doxorubicin into a cancer stem cell killer via EpCAM aptamer-mediated delivery.
Author: Xiang, Dongxi|Shigdar, Sarah|Bean, Andrew G|Bruce, Matthew|Yang, Wenrong|Mathesh, Motilal|Wang, Tao|Yin, Wang|Tran, Phuong Ha-Lien|Al Shamaileh, Hadi|Barrero, Roberto A|Zhang, Pei-Zhuo|Li, Yong|Kong, Lingxue|Liu, Ke|Zhou, Shu-Feng|Hou, Yingchun|He, Aina|D
PMID: 29158811
Journal: World J Surg Oncol. 2017 Nov 28;15(1):209.
Title: Effect of dendritic cell-cytokine-induced killer cells in patients with advanced colorectal cancer combined with first-line treatment.
Author: Xie, Yunqing|Huang, Lijie|Chen, Luchuan|Lin, Xiaowei|Chen, Li|Zheng, Qiuhong
PMID: 29179719
Journal: Oncotarget. 2017 Aug 24;8(53):91258-91269.
Title: A small molecule, (E)-2-methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) phenol suppresses tumor growth via inhibition of IkappaB kinase beta in colorectal cancer in vivo and in vitro.
Author: Zheng, Jie|Park, Mi Hee|Lee, Hee Pom|Hyun, Byung Kook|Chun, Hyung Ok|Jung, Sung Hee|Seo, Hyun Ok|Ham, Young Wan|Han, Sang-Bae|Hong, Jin Tae
PMID: 29207641
Journal: Am J Transl Res. 2017 Nov 15;9(11):4945-4953. eCollection 2017.
Title: Hsp90 inhibitor sensitizes TRAIL-mediated apoptosis via chop-dependent DR5 upregulation in colon cancer cells.
Author: Yao, Zhicheng|Chen, Ang|Li, Xin|Zhu, Zhiyong|Jiang, Xin
PMID: 29218092
Journal: Cell Cycle. 2018;17(5):557-567.
Title: CB002, a novel p53 tumor suppressor pathway-restoring small molecule induces tumor cell death through the pro-apoptotic protein NOXA.
Author: Hernandez-Borrero, Liz J|Zhang, Shengliang|Lulla, Amriti|Dicker, David T|El-Deiry, Wafik S
PMID: 28749203
Journal: Cancer Cell. 2018 Jan 8;33(1):7-9.
Title: Characterizing the Killer Colorectal Carcinomas.
Author: Hamilton, Stanley R
PMID: 29316434
Journal: Cell Death Dis. 2018 Jan 26;9(2):125.
Title: The BAX/BAK-like protein BOK is a prognostic marker in colorectal cancer.
Author: Carberry, Steven|D'Orsi, Beatrice|Monsefi, Naser|Salvucci, Manuela|Bacon, Orna|Fay, Joanna|Rehm, Markus|McNamara, Deborah|Kay, Elaine W|Prehn, Jochen H M
PMID: 29374142
Journal: Int J Cancer. 2018 Sep 15;143(6):1530-1540.
Title: Phase Ib/II study of safety and efficacy of low-dose decitabine-primed chemoimmunotherapy in patients with drug-resistant relapsed/refractory alimentary tract cancer.
Author: Chen, Meixia|Nie, Jing|Liu, Yang|Li, Xiang|Zhang, Yan|Brock, Malcolm V|Feng, Kaichao|Wu, Zhiqiang|Li, Xiaolei|Shi, Lu|Li, Suxia|Guo, Mingzhou|Mei, Qian|Han, Weidong
PMID: 29663379
Journal: Pathol Res Pract. 2018 Jun;214(6):826-834.
Title: Comprehensive expression analysis of TNF-related apoptosis-inducing ligand and its receptors in colorectal cancer: Correlation with MAPK alterations and clinicopathological associations.
Author: Tsikalakis, Spyridon|Chatziandreou, Ilenia|Michalopoulos, Nikolaos V|Theodoropoulos, Georgios E|Sakellariou, Stratigoula|Korkolopoulou, Penelope|Patsouris, Efstratios|Saetta, Angelica A
PMID: 29731264
Journal: Int J Oncol. 2018 Aug;53(2):844-854.
Title: The HDAC6 inhibitor ACY1215 enhances the anticancer activity of oxaliplatin in colorectal cancer cells.
Author: Lee, Dong Hoon|Won, Hye-Rim|Ryu, Hyun-Wook|Han, Jung Min|Kwon, So Hee
PMID: 29749542
Journal: Cancer Commun (Lond). 2018 Jul 3;38(1):43.
Title: Azithromycin enhances anticancer activity of TRAIL by inhibiting autophagy and up-regulating the protein levels of DR4/5 in colon cancer cells in vitro and in vivo.
Author: Qiao, Xinran|Wang, Xiaofei|Shang, Yue|Li, Yi|Chen, Shu-Zhen
PMID: 29970185
Journal: J Cell Biochem. 2018 Aug 30.
Title: Ferroptosis-inducing agents enhance TRAIL-induced apoptosis through upregulation of death receptor 5.
Author: Lee, Young-Sun|Lee, Dae-Hee|Jeong, So Yeon|Park, Seong Hye|Oh, Sang Cheul|Park, Yong Seok|Yu, Jian|Choudry, Haroon A|Bartlett, David L|Lee, Yong J
PMID: 30160785
Journal: Int J Oncol. 2018 Sep 14.
Title: Lipocalin 2 inversely regulates TRAIL sensitivity through p38 MAPK-mediated DR5 regulation in colorectal cancer.
Author: Kim, Se-Lim|Min, In Suk|Park, Young Ran|Lee, Soo Teik|Kim, Sang-Wook
PMID: 30221676
Journal: Asian Pac J Cancer Prev. 2018 Sep 26;19(9):2455-2460.
Title: Knowledge and Awareness of Colorectal Cancer among General Public of Kuwait
Author: Saeed, Raed Saeed|Bakir, Yousif Yacoub|Alkhalifah, Khalid Hussain|Ali, Layla Mohammed
PMID: 30255699
Journal: Cell Physiol Biochem. 2018 Sep 26;49(6):2151-2162.
Title: miR-128 Targets the SIRT1/ROS/DR5 Pathway to Sensitize Colorectal Cancer to TRAIL-Induced Apoptosis.
Author: Lian, Bo|Yang, Dongxiang|Liu, Yanlong|Shi, Gang|Li, Jibin|Yan, Xiaofei|Jin, Keer|Liu, Xin|Zhao, Jianfeng|Shang, Wen|Zhang, Rui
PMID: 30257253
Journal: Stem Cells. 2018 Oct 23.
Title: PARP inhibition sensitizes colorectal cancer-initiating cells to chemotherapy.
Author: Jarrar, Awad|Lotti, Fiorenza|DeVecchio, Jennifer|Ferrandon, Sylvain|Gantt, Gerald|Mace, Adam|Karagkounis, Georgios|Orloff, Matthew|Venere, Monica|Hitomi, Masahiro|Lathia, Justin|Rich, Jeremy N|Kalady, Matthew F
PMID: 30353615