Primary Site >> Colorectal Cancer

Gene >> TNFRSF10A

Journal: Biochem Biophys Res Commun. 2000 Mar 5;269(1):179-90.
Title: p21(WAF1/CIP1) inhibits initiator caspase cleavage by TRAIL death receptor DR4.
Author: Xu, S Q|El-Deiry, W S
PMID: 10694497
Journal: Ann N Y Acad Sci. 2000;915:162-70.
Title: Expression and function of death receptors and their natural ligands in the intestine.
Author: Strater, J|Moller, P
PMID: 11193573
Journal: Cancer Res. 2001 Feb 15;61(4):1645-51.
Title: Anticancer agents sensitize tumor cells to tumor necrosis factor-related apoptosis-inducing ligand-mediated caspase-8 activation and apoptosis.
Author: Lacour, S|Hammann, A|Wotawa, A|Corcos, L|Solary, E|Dimanche-Boitrel, M T
PMID: 11245478
Journal: J Immunol. 2001 Apr 15;166(8):4891-8.
Title: Isotype-dependent inhibition of tumor growth in vivo by monoclonal antibodies to death receptor 4.
Author: Chuntharapai, A|Dodge, K|Grimmer, K|Schroeder, K|Marsters, S A|Koeppen, H|Ashkenazi, A|Kim, K J
PMID: 11290766
Journal: Oncogene. 2001 Mar 22;20(12):1476-85.
Title: Sodium nitroprusside enhances TRAIL-induced apoptosis via a mitochondria-dependent pathway in human colorectal carcinoma CX-1 cells.
Author: Lee, Y J|Lee, K H|Kim, H R|Jessup, J M|Seol, D W|Kim, T H|Billiar, T R|Song, Y K
PMID: 11313891
Journal: Oncogene. 2001 Feb 1;20(5):571-80.
Title: p53 upregulates cFLIP, inhibits transcription of NF-kappaB-regulated genes and induces caspase-8-independent cell death in DLD-1 cells.
Author: Bartke, T|Siegmund, D|Peters, N|Reichwein, M|Henkler, F|Scheurich, P|Wajant, H
PMID: 11313989
Journal: J Biol Chem. 2001 Oct 12;276(41):37879-86.
Title: Identification of inhibitors of TRAIL-induced death (ITIDs) in the TRAIL-sensitive colon carcinoma cell line SW480 using a genetic approach.
Author: Burns, T F|El-Deiry, W S
PMID: 11486001
Journal: Gastroenterology. 2002 Mar;122(3):659-66.
Title: TRAIL and its receptors in the colonic epithelium: a putative role in the defense of viral infections.
Author: Strater, Jorn|Walczak, Henning|Pukrop, Tanja|Von Muller, Lutz|Hasel, Cornelia|Kornmann, Marko|Mertens, Thomas|Moller, Peter
PMID: 11874999
Journal: J Biol Chem. 2002 Sep 27;277(39):36602-10. Epub 2002 Jul 24.
Title: Regulation of TRAIL expression by the phosphatidylinositol 3-kinase/Akt/GSK-3 pathway in human colon cancer cells.
Author: Wang, Qingding|Wang, Xiaofu|Hernandez, Ambrosio|Hellmich, Mark R|Gatalica, Zoran|Evers, B Mark
PMID: 12140294
Journal: Cancer Res. 2002 Oct 15;62(20):5800-6.
Title: Effects of tumor necrosis factor-related apoptosis-inducing ligand alone and in combination with chemotherapeutic agents on patients' colon tumors grown in SCID mice.
Author: Naka, Takuji|Sugamura, Kenji|Hylander, Bonnie L|Widmer, Michael B|Rustum, Youcef M|Repasky, Elizabeth A
PMID: 12384541
Journal: Clin Cancer Res. 2002 Dec;8(12):3734-40.
Title: Expression of TRAIL and TRAIL receptors in colon carcinoma: TRAIL-R1 is an independent prognostic parameter.
Author: Strater, Jorn|Hinz, Ulf|Walczak, Henning|Mechtersheimer, Gunhild|Koretz, Karin|Herfarth, Christian|Moller, Peter|Lehnert, Thomas
PMID: 12473583
Journal: J Natl Cancer Inst. 2003 Apr 16;95(8):611-21.
Title: Macrophages from cancer patients: analysis of TRAIL, TRAIL receptors, and colon tumor cell apoptosis.
Author: Herbeuval, Jean-Philippe|Lambert, Claude|Sabido, Odile|Cottier, Michele|Fournel, Pierre|Dy, Michel|Genin, Christian
PMID: 12697854
Journal: J Pathol. 2003 Jul;200(3):327-35.
Title: Expression of TRAIL (TNF-related apoptosis-inducing ligand) and its receptors in normal colonic mucosa, adenomas, and carcinomas.
Author: Koornstra, Jan J|Kleibeuker, Jan H|van Geelen, Caroline M M|Rijcken, Fleur E M|Hollema, Harry|de Vries, Elisabeth G E|de Jong, Steven
PMID: 12845629
Journal: Br J Cancer. 2003 Jul 21;89(2):363-73.
Title: Differential modulation of the TRAIL receptors and the CD95 receptor in colon carcinoma cell lines.
Author: van Geelen, C M M|de Vries, E G E|Le, T K P|van Weeghel, R P|de Jong, S
PMID: 12865931
Journal: Exp Cell Res. 2004 Feb 1;293(1):129-43.
Title: Low extracellular pH augments TRAIL-induced apoptotic death through the mitochondria-mediated caspase signal transduction pathway.
Author: Lee, Yong J|Song, Jae J|Kim, Jin H|Kim, Hyeong-Reh Choi|Song, Young K
PMID: 14729063
Journal: Carcinogenesis. 2004 Oct;25(10):1813-20.
Title: Sodium butyrate sensitizes TRAIL-mediated apoptosis by induction of transcription from the DR5 gene promoter through Sp1 sites in colon cancer cells.
Author: Kim, Young-Ho|Park, Jong-Wook|Lee, Jai-Youl|Kwon, Taeg Kyu
PMID: 15142888
Journal: J Biol Chem. 2004 Aug 20;279(34):35829-39. Epub 2004 May 20.
Title: Deficient tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor transport to the cell surface in human colon cancer cells selected for resistance to TRAIL-induced apoptosis.
Author: Jin, Zhaoyu|McDonald, E Robert 3rd|Dicker, David T|El-Deiry, Wafik S
PMID: 15155747
Journal: Oncogene. 2004 Nov 25;23(55):8979-86.
Title: Redistribution of CD95, DR4 and DR5 in rafts accounts for the synergistic toxicity of resveratrol and death receptor ligands in colon carcinoma cells.
Author: Delmas, Dominique|Rebe, Cedric|Micheau, Olivier|Athias, Anne|Gambert, Philippe|Grazide, Solene|Laurent, Guy|Latruffe, Norbert|Solary, Eric
PMID: 15480430
Journal: Cancer Res. 2004 Dec 15;64(24):9105-14.
Title: Elimination of hepatic metastases of colon cancer cells via p53-independent cross-talk between irinotecan and Apo2 ligand/TRAIL.
Author: Ravi, Rajani|Jain, Ajay J|Schulick, Richard D|Pham, Vui|Prouser, Traci S|Allen, Heather|Mayer, Elizabeth Garrett|Yu, Hua|Pardoll, Drew M|Ashkenazi, Avi|Bedi, Atul
PMID: 15604280
Journal: Drug Resist Updat. 2004 Dec;7(6):345-58.
Title: Lessons from TRAIL-resistance mechanisms in colorectal cancer cells: paving the road to patient-tailored therapy.
Author: Van Geelen, Caroline M M|de Vries, Elisabeth G E|de Jong, Steven
PMID: 15790545
Journal:
Title: (99m)Tc-Labeled lexatumumab
Author: Chopra, Arvind
PMID: 20641185
Journal:
Title: (99m)Tc-Labeled mapatumumab
Author: Chopra, Arvind
PMID: 20641397
Journal:
Title: (111)In-Labeled mapatumumab
Author: Chopra, Arvind
PMID: 20641403
Journal: Br J Cancer. 2005 Feb 28;92(4):736-42.
Title: Increased sensitivity to TRAIL-induced apoptosis occurs during the adenoma to carcinoma transition of colorectal carcinogenesis.
Author: Hague, A|Hicks, D J|Hasan, F|Smartt, H|Cohen, G M|Paraskeva, C|MacFarlane, M
PMID: 15685228
Journal: J Biol Chem. 2005 Jun 17;280(24):22856-67.
Title: Transformation by oncogenic RAS sensitizes human colon cells to TRAIL-induced apoptosis by up-regulating death receptor 4 and death receptor 5 through a MEK-dependent pathway.
Author: Drosopoulos, Konstantinos G|Roberts, Michael L|Cermak, Lukas|Sasazuki, Takehiko|Shirasawa, Senji|Andera, Ladislav|Pintzas, Alexander
PMID: 15757891
Journal: Br J Cancer. 2005 Apr 25;92(8):1430-41.
Title: HGS-ETR1, a fully human TRAIL-receptor 1 monoclonal antibody, induces cell death in multiple tumour types in vitro and in vivo.
Author: Pukac, L|Kanakaraj, P|Humphreys, R|Alderson, R|Bloom, M|Sung, C|Riccobene, T|Johnson, R|Fiscella, M|Mahoney, A|Carrell, J|Boyd, E|Yao, X T|Zhang, L|Zhong, L|von Kerczek, A|Shepard, L|Vaughan, T|Edwards, B|Dobson, C|Salcedo, T|Albert, V
PMID: 15846298
Journal: Eur J Cancer. 2005 May;41(8):1195-202.
Title: Expression of tumour necrosis factor-related apoptosis-inducing ligand death receptors in sporadic and hereditary colorectal tumours: potential targets for apoptosis induction.
Author: Koornstra, Jan J|Jalving, Mathilde|Rijcken, Fleur E M|Westra, Jantine|Zwart, Nynke|Hollema, Harry|de Vries, Elisabeth G E|Hofstra, Robert W M|Plukker, John T M|de Jong, Steven|Kleibeuker, Jan H
PMID: 15911244
Journal: Cancer Biol Ther. 2005 Jul;4(7):781-6. Epub 2005 Jul 6.
Title: Proteasome inhibitors-mediated TRAIL resensitization and Bik accumulation.
Author: Zhu, Hongbo|Guo, Wei|Zhang, Lidong|Wu, Shuhong|Teraishi, Fuminori|Davis, John J|Dong, Fengqin|Fang, Bingliang
PMID: 16082182
Journal: Mol Cancer Ther. 2005 Oct;4(10):1475-83.
Title: Sulindac sulfide-induced apoptosis is enhanced by a small-molecule Bcl-2 inhibitor and by TRAIL in human colon cancer cells overexpressing Bcl-2.
Author: Sinicrope, Frank A|Penington, Robert C
PMID: 16227396
Journal: Mol Cancer Ther. 2005 Dec;4(12):2026-36.
Title: Chemotherapy and TRAIL-mediated colon cancer cell death: the roles of p53, TRAIL receptors, and c-FLIP.
Author: Galligan, Leeona|Longley, Daniel B|McEwan, Miranda|Wilson, Timothy R|McLaughlin, Kirsty|Johnston, Patrick G
PMID: 16373718
Journal: Cancer Epidemiol Biomarkers Prev. 2006 Oct;15(10):2002-5.
Title: Death receptor 4 variants and colorectal cancer risk.
Author: Frank, Bernd|Shanmugam, Kalai Selvi|Beckmann, Lars|Hemminki, Kari|Brenner, Hermann|Hoffmeister, Michael|Chang-Claude, Jenny|Burwinkel, Barbara
PMID: 17035413
Journal: Cancer Res. 2007 Jun 15;67(12):5754-62.
Title: c-FLIP: a key regulator of colorectal cancer cell death.
Author: Wilson, Timothy R|McLaughlin, Kirsty M|McEwan, Miranda|Sakai, Hidekazu|Rogers, Katherine M A|Redmond, Kelly M|Johnston, Patrick G|Longley, Daniel B
PMID: 17575142
Journal: Cancer Res. 2007 Jul 15;67(14):6987-94.
Title: Histone deacetylase inhibitors enhance lexatumumab-induced apoptosis via a p21Cip1-dependent decrease in survivin levels.
Author: Nawrocki, Steffan T|Carew, Jennifer S|Douglas, Leslie|Cleveland, John L|Humphreys, Robin|Houghton, Janet A
PMID: 17638911
Journal: Clin Lung Cancer. 2007 Jul;8(7):413-9.
Title: The potential of death receptor 4- and 5-directed therapies in the treatment of lung cancer.
Author: Camidge, D Ross
PMID: 17681093
Journal: Clin Cancer Res. 2007 Sep 1;13(17):5070-5.
Title: Overexpression of FLIPL is an independent marker of poor prognosis in colorectal cancer patients.
Author: Ullenhag, Gustave J|Mukherjee, Abhik|Watson, Nicholas F S|Al-Attar, Ahmad H|Scholefield, John H|Durrant, Lindy G
PMID: 17785559
Journal: Mol Cancer Ther. 2007 Sep;6(9):2591-9.
Title: Quercetin enhances TRAIL-mediated apoptosis in colon cancer cells by inducing the accumulation of death receptors in lipid rafts.
Author: Psahoulia, Faiy H|Drosopoulos, Konstantinos G|Doubravska, Lenka|Andera, Ladislav|Pintzas, Alexander
PMID: 17876056
Journal: Oncol Rep. 2008 Feb;19(2):567-73.
Title: Response of normal and colon cancer epithelial cells to TNF-family apoptotic inducers.
Author: Hofmanova, Jirina|Vaculova, Alena|Hyzd'alova, Martina|Kozubik, Alois
PMID: 18202809
Journal: Cancer Res. 2008 Feb 1;68(3):909-17.
Title: DR5 receptor mediates anoikis in human colorectal carcinoma cell lines.
Author: Laguinge, Luciana M|Samara, Raed N|Wang, Wenge|El-Deiry, Wafik S|Corner, Georgia|Augenlicht, Leonard|Mishra, Lopa|Jessup, J Milburn
PMID: 18245494
Journal: Int J Colorectal Dis. 2008 Jun;23(6):569-80.
Title: Gene profiling of colonic serrated adenomas by using oligonucleotide microarray.
Author: Kim, Kyongrae|Park, Ungchae|Wang, Joonho|Lee, Jaedong|Park, Seunghwa|Kim, Sangyoon|Choi, Dongkug|Kim, Changil|Park, Jiyoung
PMID: 18305945
Journal: BMC Cancer. 2008 Jul 1;8:187.
Title: Metastatic susceptibility locus, an 8p hot-spot for tumour progression disrupted in colorectal liver metastases: 13 candidate genes examined at the DNA, mRNA and protein level.
Author: Macartney-Coxson, Donia P|Hood, Kylie A|Shi, Hong-jun|Ward, Teresa|Wiles, Anna|O'Connor, Rosemary|Hall, David A|Lea, Rod A|Royds, Janice A|Stubbs, Richard S|Rooker, Serena
PMID: 18590575
Journal: Biochem Biophys Res Commun. 2008 Oct 10;375(1):129-33.
Title: Kaempferol sensitizes colon cancer cells to TRAIL-induced apoptosis.
Author: Yoshida, Tatsushi|Konishi, Masako|Horinaka, Mano|Yasuda, Takashi|Goda, Ahmed E|Taniguchi, Hiroya|Yano, Kimihiro|Wakada, Miki|Sakai, Toshiyuki
PMID: 18680719
Journal: Eur J Cancer. 2008 Oct;44(15):2312-8.
Title: Prognostic significance of TRAIL-R1 and TRAIL-R3 expression in metastatic colorectal carcinomas.
Author: Granci, Virginie|Bibeau, Frederic|Kramar, Andrew|Boissiere-Michot, Florence|Thezenas, Simon|Thirion, Agnes|Gongora, Celine|Martineau, Pierre|Del Rio, Maguy|Ychou, Marc
PMID: 18755584
Journal: Strahlenther Onkol. 2009 Jan;185(1):8-18.
Title: Efficacy of a triple treatment with irradiation, agonistic TRAIL receptor antibodies and EGFR blockade.
Author: Niyazi, Maximilian|Marini, Patrizia|Daniel, Peter T|Humphreys, Robin|Jendrossek, Verena|Belka, Claus
PMID: 19224142
Journal: Br J Cancer. 2009 May 5;100(9):1415-24.
Title: Differential activation of JNK1 isoforms by TRAIL receptors modulate apoptosis of colon cancer cell lines.
Author: Mahalingam, D|Keane, M|Pirianov, G|Mehmet, H|Samali, A|Szegezdi, E
PMID: 19352384
Journal: Oncol Rep. 2009 Jun;21(6):1455-60.
Title: Efficacy of triple therapies including ionising radiation, agonistic TRAIL antibodies and cisplatin.
Author: Niyazi, Maximilian|Marini, Patrizia|Daniel, Peter T|Humphreys, Robin|Jendrossek, Verena|Belka, Claus
PMID: 19424623
Journal: J Cell Mol Med. 2009 Nov-Dec;13(11-12):4409-14.
Title: Stem cells are resistant to TRAIL receptor-mediated apoptosis.
Author: Szegezdi, Eva|O'Reilly, Aoife|Davy, Yeung|Vawda, Reaz|Taylor, Deanna L|Murphy, Mary|Samali, Afshin|Mehmet, Huseyin
PMID: 19604313
Journal: Int J Cancer. 2009 Nov 1;125(9):2127-35.
Title: TRAIL receptor upregulation and the implication of KRAS/BRAF mutations in human colon cancer tumors.
Author: Oikonomou, Eftychia|Kosmidou, Vivian|Katseli, Anastasia|Kothonidis, Konstantinos|Mourtzoukou, Despina|Kontogeorgos, George|Andera, Ladislav|Zografos, Georgios|Pintzas, Alexander
PMID: 19637313
Journal: Cancer Res. 2009 Aug 15;69(16):6581-9.
Title: Zerumbone enhances TRAIL-induced apoptosis through the induction of death receptors in human colon cancer cells: Evidence for an essential role of reactive oxygen species.
Author: Yodkeeree, Supachai|Sung, Bokyung|Limtrakul, Pornngarm|Aggarwal, Bharat B
PMID: 19654295
Journal: Cancer Lett. 2010 Jan 1;287(1):98-108.
Title: Nutlin-3 enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through up-regulation of death receptor 5 (DR5) in human sarcoma HOS cells and human colon cancer HCT116 cells.
Author: Hori, Takeshi|Kondo, Takashi|Kanamori, Masahiko|Tabuchi, Yoshiaki|Ogawa, Ryohei|Zhao, Qing-Li|Ahmed, Kanwal|Yasuda, Taketoshi|Seki, Shoji|Suzuki, Kayo|Kimura, Tomoatsu
PMID: 19577358
Journal: Biochem Biophys Res Commun. 2010 Jan 8;391(2):1274-9.
Title: Hypoxia-induced decoy receptor 2 gene expression is regulated via a hypoxia-inducible factor 1alpha-mediated mechanism.
Author: Pei, Guo-Ting|Wu, Chi-Wei|Lin, Wan-Wan
PMID: 20018172
Journal: Br J Cancer. 2010 Feb 2;102(3):506-12.
Title: Phase II trial of mapatumumab, a fully human agonistic monoclonal antibody that targets and activates the tumour necrosis factor apoptosis-inducing ligand receptor-1 (TRAIL-R1), in patients with refractory colorectal cancer.
Author: Trarbach, T|Moehler, M|Heinemann, V|Kohne, C-H|Przyborek, M|Schulz, C|Sneller, V|Gallant, G|Kanzler, S
PMID: 20068564
Journal: Br J Cancer. 2010 Feb 16;102(4):754-64.
Title: Early growth response-1 is a regulator of DR5-induced apoptosis in colon cancer cells.
Author: Mahalingam, D|Natoni, A|Keane, M|Samali, A|Szegezdi, E
PMID: 20087343
Journal: Cancer Biol Ther. 2010 Apr 15;9(8):618-31. Epub 2010 Apr 20.
Title: Conatumumab, a fully human agonist antibody to death receptor 5, induces apoptosis via caspase activation in multiple tumor types.
Author: Kaplan-Lefko, Paula J|Graves, Jonathan D|Zoog, Stephen J|Pan, Yang|Wall, Jason|Branstetter, Daniel G|Moriguchi, Jodi|Coxon, Angela|Huard, Justin N|Xu, Ren|Peach, Matthew L|Juan, Gloria|Kaufman, Stephen|Chen, Qing|Bianchi, Allison|Kordich, Jennifer J|Ma, M
PMID: 20150762
Journal: FEBS J. 2010 Apr;277(7):1653-65.
Title: Synthetic constrained peptide selectively binds and antagonizes death receptor 5.
Author: Vrielink, Johanna|Heins, Mariette S|Setroikromo, Rita|Szegezdi, Eva|Mullally, Margaret M|Samali, Afshin|Quax, Wim J
PMID: 20156289
Journal: Eur J Cancer. 2010 Aug;46(12):2314-23.
Title: Tumour-mediated TRAIL-Receptor expression indicates effective apoptotic depletion of infiltrating CD8+ immune cells in clinical colorectal cancer.
Author: Grimm, Martin|Kim, Mia|Rosenwald, Andreas|von Raden, Burkhard H A|Tsaur, Igor|Meier, Eva|Heemann, Uwe|Germer, Christoph-Thomas|Gasser, Martin|Waaga-Gasser, Ana Maria
PMID: 20580220
Journal: Mol Cancer. 2010 Jul 30;9:203.
Title: Prognostic significance of TRAIL death receptors in Middle Eastern colorectal carcinomas and their correlation to oncogenic KRAS alterations.
Author: Bavi, Prashant|Prabhakaran, Sarita E|Abubaker, Jehad|Qadri, Zeeshan|George, Thara|Al-Sanea, Nasser|Abduljabbar, Alaa|Ashari, Luai H|Alhomoud, Samar|Al-Dayel, Fouad|Hussain, Azhar R|Uddin, Shahab|Al-Kuraya, Khawla S
PMID: 20673328
Journal: Int J Oncol. 2010 Oct;37(4):1031-41.
Title: Downregulation of active caspase 8 as a mechanism of acquired TRAIL resistance in mismatch repair-proficient colon carcinoma cell lines.
Author: Van Geelen, Caroline M M|Pennarun, Bodvael|Ek, Wytske Boerma-Van|Le, Phuong T K|Spierings, Diana C J|De Vries, Elisabeth G E|De Jong, Steven
PMID: 20811726
Journal: Anal Cell Pathol (Amst). 2010;33(5):229-44.
Title: Inhibition of IGF-1R-dependent PI3K activation sensitizes colon cancer cells specifically to DR5-mediated apoptosis but not to rhTRAIL.
Author: Pennarun, Bodvael|Kleibeuker, Jan H|Oenema, Tjitske|Stegehuis, Janet H|de Vries, Elisabeth G E|de Jong, Steven
PMID: 20978316
Journal: Biomedica. 2010 Oct-Dec;30(4):577-86.
Title: Implication of NF-kappaB and p53 in the expression of TRAIL-death receptors and apoptosis by apple procyanidins in human metastatic SW620 cells.
Author: Maldonado, Maria Elena|Bousserouel, Souad|Gosse, Francine|Lobstein, Annelise|Raul, Francis
PMID: 21713362
Journal: Carcinogenesis. 2011 Jan;32(1):42-51.
Title: Cisplatin and a potent platinum(IV) complex-mediated enhancement of TRAIL-induced cancer cells killing is associated with modulation of upstream events in the extrinsic apoptotic pathway.
Author: Vondalova Blanarova, Olga|Jelinkova, Iva|Szoor, Arpad|Skender, Belma|Soucek, Karel|Horvath, Viktor|Vaculova, Alena|Andera, Ladislav|Sova, Petr|Szollosi, Janos|Hofmanova, Jirina|Vereb, Gyorgy|Kozubik, Alois
PMID: 21037225
Journal: Cancer Res. 2011 Jan 15;71(2):538-49.
Title: ROS and CHOP are critical for dibenzylideneacetone to sensitize tumor cells to TRAIL through induction of death receptors and downregulation of cell survival proteins.
Author: Prasad, Sahdeo|Yadav, Vivek R|Ravindran, Jayaraj|Aggarwal, Bharat B
PMID: 21127198
Journal: Br J Pharmacol. 2011 Nov;164(5):1433-44.
Title: Methyl jasmonate down-regulates survivin expression and sensitizes colon carcinoma cells towards TRAIL-induced cytotoxicity.
Author: Raviv, Z|Zilberberg, A|Cohen, S|Reischer-Pelech, D|Horrix, C|Berger, M R|Rosin-Arbesfeld, R|Flescher, E
PMID: 21486277
Journal: Cell Oncol (Dordr). 2011 Jun;34(3):245-59.
Title: Inhibition of IGF-1R-dependent PI3K activation sensitizes colon cancer cells specifically to DR5-mediated apoptosis but not to rhTRAIL.
Author: Pennarun, Bodvael|Kleibeuker, Jan H|Oenema, Tjitske|Stegehuis, Janet H|de Vries, Elisabeth G E|de Jong, Steven
PMID: 21538027
Journal: Sci Transl Med. 2011 Jun 8;3(86):86ra50.
Title: Off-target lapatinib activity sensitizes colon cancer cells through TRAIL death receptor up-regulation.
Author: Dolloff, Nathan G|Mayes, Patrick A|Hart, Lori S|Dicker, David T|Humphreys, Robin|El-Deiry, Wafik S
PMID: 21653830
Journal: Apoptosis. 2011 Oct;16(10):1042-53.
Title: Silibinin triggers apoptotic signaling pathways and autophagic survival response in human colon adenocarcinoma cells and their derived metastatic cells.
Author: Kauntz, Henriette|Bousserouel, Souad|Gosse, Francine|Raul, Francis
PMID: 21779837
Journal: J Biol Chem. 2011 Dec 16;286(50):43123-33.
Title: GDP-mannose-4,6-dehydratase (GMDS) deficiency renders colon cancer cells resistant to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor- and CD95-mediated apoptosis by inhibiting complex II formation.
Author: Moriwaki, Kenta|Shinzaki, Shinichiro|Miyoshi, Eiji
PMID: 22027835
Journal: J Cell Biochem. 2012 May;113(5):1547-58.
Title: Hyperthermia-enhanced TRAIL- and mapatumumab-induced apoptotic death is mediated through mitochondria in human colon cancer cells.
Author: Song, Xinxin|Kim, Han-Cheon|Kim, Seog-Young|Basse, Per|Park, Bae-Hang|Lee, Byeong-Chel|Lee, Yong J
PMID: 22174016
Journal: PLoS One. 2012;7(2):e31762.
Title: Sub-lethal irradiation of human colorectal tumor cells imparts enhanced and sustained susceptibility to multiple death receptor signaling pathways.
Author: Ifeadi, Victoria|Garnett-Benson, Charlie
PMID: 22389673
Journal: Cell Death Dis. 2012 Apr 12;3:e295.
Title: Superior antitumoral activity of dimerized targeted single-chain TRAIL fusion proteins under retention of tumor selectivity.
Author: Siegemund, M|Pollak, N|Seifert, O|Wahl, K|Hanak, K|Vogel, A|Nussler, A K|Gottsch, D|Munkel, S|Bantel, H|Kontermann, R E|Pfizenmaier, K
PMID: 22495350
Journal: Apoptosis. 2012 Aug;17(8):797-809.
Title: The flavonolignan silibinin potentiates TRAIL-induced apoptosis in human colon adenocarcinoma and in derived TRAIL-resistant metastatic cells.
Author: Kauntz, Henriette|Bousserouel, Souad|Gosse, Francine|Raul, Francis
PMID: 22555452
Journal: Free Radic Biol Med. 2012 Nov 15;53(10):1977-87.
Title: Capsazepine, a TRPV1 antagonist, sensitizes colorectal cancer cells to apoptosis by TRAIL through ROS-JNK-CHOP-mediated upregulation of death receptors.
Author: Sung, Bokyung|Prasad, Sahdeo|Ravindran, Jayaraj|Yadav, Vivek R|Aggarwal, Bharat B
PMID: 22922338
Journal: Int J Mol Med. 2012 Nov;30(5):1087-94.
Title: The synergistic effects of low-dose irinotecan and TRAIL on TRAIL-resistant HT-29 colon carcinoma in vitro and in vivo.
Author: Zhu, Hong|Zhao, Fen|Yu, Shuijing|He, Jianping|Deng, Licong|Yi, Cheng|Huang, Ying
PMID: 22922573
Journal: Nat Mater. 2012 Dec;11(12):1038-43.
Title: A magnetic switch for the control of cell death signalling in in vitro and in vivo systems.
Author: Cho, Mi Hyeon|Lee, Eun Jung|Son, Mina|Lee, Jae-Hyun|Yoo, Dongwon|Kim, Ji-wook|Park, Seung Woo|Shin, Jeon-Soo|Cheon, Jinwoo
PMID: 23042417
Journal: Mol Cancer Res. 2012 Dec;10(12):1567-79.
Title: The role of Bcl-xL in synergistic induction of apoptosis by mapatumumab and oxaliplatin in combination with hyperthermia on human colon cancer.
Author: Song, Xinxin|Kim, Seog-Young|Lee, Yong J
PMID: 23051936
Journal: Oncol Rep. 2013 Feb;29(2):474-80.
Title: Casticin, a flavonoid, potentiates TRAIL-induced apoptosis through modulation of anti-apoptotic proteins and death receptor 5 in colon cancer cells.
Author: Tang, San-Yuan|Zhong, Mei-Zuo|Yuan, Guang-Jin|Hou, Su-Ping|Yin, Lei-Lan|Jiang, Hao|Yu, Zheng-Upsilonang
PMID: 23135489
Journal: Cell Death Dis. 2013 Feb 21;4:e503.
Title: Delivery of sTRAIL variants by MSCs in combination with cytotoxic drug treatment leads to p53-independent enhanced antitumor effects.
Author: Yu, R|Deedigan, L|Albarenque, S M|Mohr, A|Zwacka, R M
PMID: 23429289
Journal: Free Radic Biol Med. 2013 Oct;63:280-90.
Title: Aldose reductase inhibition enhances TRAIL-induced human colon cancer cell apoptosis through AKT/FOXO3a-dependent upregulation of death receptors.
Author: Shoeb, Mohammad|Ramana, Kota V|Srivastava, Satish K
PMID: 23732517
Journal: PLoS One. 2013 Aug 27;8(8):e73654.
Title: Evidence for two modes of synergistic induction of apoptosis by mapatumumab and oxaliplatin in combination with hyperthermia in human colon cancer cells.
Author: Song, Xinxin|Kim, Seog-Young|Lee, Yong J
PMID: 24013390
Journal: Cancer Sci. 2013 Dec;104(12):1632-9.
Title: Amurensin G enhances the susceptibility to tumor necrosis factor-related apoptosis-inducing ligand-mediated cytotoxicity of cancer stem-like cells of HCT-15 cells.
Author: Lee, Su-Hoon|Kim, Mi-Ju|Kim, Dong-Wan|Kang, Chi-Dug|Kim, Sun-Hee
PMID: 24118446
Journal: Biomark Cancer. 2013 Jul 4;5:13-29.
Title: The prognostic value of the apoptosis pathway in colorectal cancer: a review of the literature on biomarkers identified by immunohistochemistry.
Author: Zeestraten, Eliane C M|Benard, Anne|Reimers, Marlies S|Schouten, Philip C|Liefers, Gerrit J|van de Velde, Cornelis J H|Kuppen, Peter J K
PMID: 24179395
Journal: Carcinogenesis. 2014 May;35(5):1092-9.
Title: Regulation of TRAIL receptor expression by beta-catenin in colorectal tumours.
Author: Jalving, M|Heijink, D M|Koornstra, J J|Boersma-van Ek, W|Zwart, N|Wesseling, J|Sluiter, W J|de Vries, E G E|Kleibeuker, J H|de Jong, S
PMID: 24379239
Journal: Oncol Lett. 2014 May;7(5):1728-1732.
Title: Laminarin-induced apoptosis in human colon cancer LoVo cells.
Author: Ji, Chen-Feng|Ji, Yu-Bin
PMID: 24765209
Journal: Food Chem Toxicol. 2014 Sep;71:51-9.
Title: Ilimaquinone induces death receptor expression and sensitizes human colon cancer cells to TRAIL-induced apoptosis through activation of ROS-ERK/p38 MAPK-CHOP signaling pathways.
Author: Do, Minh Truong|Na, MinKyun|Kim, Hyung Gyun|Khanal, Tilak|Choi, Jae Ho|Jin, Sun Woo|Oh, Seok Hoon|Hwang, In Hyun|Chung, Young Chul|Kim, Hee Suk|Jeong, Tae Cheon|Jeong, Hye Gwang
PMID: 24930757
Journal: Oncogene. 2015 Feb 26;34(9):1150-9.
Title: Functional characterization of the tumor-suppressor MARCKS in colorectal cancer and its association with survival.
Author: Bickeboller, M|Tagscherer, K E|Kloor, M|Jansen, L|Chang-Claude, J|Brenner, H|Hoffmeister, M|Toth, C|Schirmacher, P|Roth, W|Blaker, H
PMID: 24662837
Journal: Tumour Biol. 2015 May;36(5):3775-89.
Title: Antimicrobial peptide m2163 or m2386 identified from Lactobacillus casei ATCC 334 can trigger apoptosis in the human colorectal cancer cell line SW480.
Author: Tsai, Tsung-Lin|Li, An-Chieh|Chen, Yi-Chieh|Liao, Yi-Shun|Lin, Thy-Hou
PMID: 25557887
Journal: J Pharmacol Sci. 2015 Jan;127(1):83-91.
Title: TRAIL pathway is associated with inhibition of colon cancer by protopanaxadiol.
Author: Zhang, Zhiyu|Li, Zejuan|Wu, Xiaohui|Zhang, Chun-Feng|Calway, Tyler|He, Tong-Chuan|Du, Wei|Chen, Jianjun|Wang, Chong-Zhi|Yuan, Chun-Su
PMID: 25704023
Journal: Cell Mol Biol (Noisy-le-grand). 2015 Oct 30;61(6):108-12.
Title: Genetic variants in the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and death receptor (DR4) genes contribute to susceptibility to colorectal cancer in pakistani population.
Author: Zahoor, A|Mansoor, Q|Farooqi, A A|Fayyaz, S|Naz, G|Ismail, M
PMID: 26518902
Journal: Cell Mol Biol (Noisy-le-grand). 2015 Oct 30;61(6):1.
Title: Editorial.
Author: Farooqi, A A|Ismail, M
PMID: 26520390
Journal: Oncotarget. 2015 Dec 29;6(42):44437-51.
Title: Anti-cancer effect of bee venom on colon cancer cell growth by activation of death receptors and inhibition of nuclear factor kappa B.
Author: Zheng, Jie|Lee, Hye Lim|Ham, Young Wan|Song, Ho Sueb|Song, Min Jong|Hong, Jin Tae
PMID: 26561202
Journal: Oncotarget. 2016 Feb 9;7(6):7161-78.
Title: The probiotic Propionibacterium freudenreichii as a new adjuvant for TRAIL-based therapy in colorectal cancer.
Author: Cousin, Fabien J|Jouan-Lanhouet, Sandrine|Theret, Nathalie|Brenner, Catherine|Jouan, Elodie|Le Moigne-Muller, Gwenaelle|Dimanche-Boitrel, Marie-Therese|Jan, Gwenael
PMID: 26771233
Journal: Biochem Biophys Res Commun. 2016 Apr 29;473(2):586-92.
Title: Bakuchiol sensitizes cancer cells to TRAIL through ROS- and JNK-mediated upregulation of death receptors and downregulation of survival proteins.
Author: Park, Mi Hee|Kim, Jong Han|Chung, Young-Ho|Lee, Seung Ho
PMID: 27033605
Journal: Apoptosis. 2016 Nov;21(11):1291-1301.
Title: Gefitinib enhances human colon cancer cells to TRAIL-induced apoptosis of via autophagy- and JNK-mediated death receptors upregulation.
Author: Chen, Lei|Meng, Yue|Guo, Xiaoqing|Sheng, Xiaotong|Tai, Guihua|Zhang, Fenglei|Cheng, Hairong|Zhou, Yifa
PMID: 27629794
Journal: Cancer Lett. 2016 Dec 28;383(2):145-153.
Title: BAY61-3606 potentiates the anti-tumor effects of TRAIL against colon cancer through up-regulating DR4 and down-regulating NF-kappaB.
Author: Du, Jipei|Wang, Yufang|Chen, Degao|Ji, Guangyu|Ma, Qizhao|Liao, Shiping|Zheng, Yanjiang|Zhang, Ji|Hou, Yiping
PMID: 27721019
Journal: Sci Rep. 2016 Nov 9;6:36532.
Title: Death receptor 5 (DR5) and a 5-gene apoptotic biomarker panel with significant differential diagnostic potential in colorectal cancer.
Author: Devetzi, Marina|Kosmidou, Vivian|Vlassi, Margarita|Perysinakis, Iraklis|Aggeli, Chrysanthi|Choreftaki, Theodosia|Zografos, Georgios N|Pintzas, Alexander
PMID: 27827395
Journal: Anticancer Drugs. 2017 Jan;28(1):66-74.
Title: Tunicamycin enhances human colon cancer cells to TRAIL-induced apoptosis by JNK-CHOP-mediated DR5 upregulation and the inhibition of the EGFR pathway.
Author: Guo, Xiaoqing|Meng, Yue|Sheng, Xiaotong|Guan, Yuan|Zhang, Fenglei|Han, Zhen|Kang, Yuying|Tai, Guihua|Zhou, Yifa|Cheng, Hairong
PMID: 27603596
Journal: Oncol Lett. 2017 Mar;13(3):1470-1478.
Title: Anticancer activity of Nelumbo nucifera stamen extract in human colon cancer HCT-116 cells in vitro.
Author: Zhao, Xin|Feng, Xia|Wang, Cun|Peng, Deguang|Zhu, Kai|Song, Jia-Le
PMID: 28454279
Journal: Drug Deliv. 2017 Nov;24(1):1526-1536.
Title: TRAIL and curcumin codelivery nanoparticles enhance TRAIL-induced apoptosis through upregulation of death receptors.
Author: Yang, Xi|Li, Zhaojun|Wu, Qinjie|Chen, Shouchun|Yi, Cheng|Gong, Changyang
PMID: 28994313
Journal: Int J Cancer. 2018 Jul 15;143(2):289-297.
Title: DR4 mediates the progression, invasion, metastasis and survival of colorectal cancer through the Sp1/NF1 switch axis on genomic locus.
Author: Wu, Shenshen|Meng, Qingtao|Zhang, Chengcheng|Sun, Hao|Lu, Runze|Gao, Na|Yang, Hongbao|Li, Xiaobo|Aschner, Michael|Chen, Rui
PMID: 29446085
Journal: Med Sci Monit. 2018 Apr 26;24:2550-2561.
Title: Effects of Recombinant Circularly Permuted Tumor Necrosis Factor (TNF)-Related Apoptosis-Inducing Ligand (TRAIL) (Recombinant Mutant Human TRAIL) in Combination with 5-Fluorouracil in Human Colorectal Cancer Cell Lines HCT116 and SW480.
Author: Sun, Tongyou|Zhu, Tienian|Liang, Xiujun|Yang, Shifang|Zhao, Ruijing
PMID: 29695684
Journal: Pathol Res Pract. 2018 Jun;214(6):826-834.
Title: Comprehensive expression analysis of TNF-related apoptosis-inducing ligand and its receptors in colorectal cancer: Correlation with MAPK alterations and clinicopathological associations.
Author: Tsikalakis, Spyridon|Chatziandreou, Ilenia|Michalopoulos, Nikolaos V|Theodoropoulos, Georgios E|Sakellariou, Stratigoula|Korkolopoulou, Penelope|Patsouris, Efstratios|Saetta, Angelica A
PMID: 29731264
Journal: Cancer Commun (Lond). 2018 Jul 3;38(1):43.
Title: Azithromycin enhances anticancer activity of TRAIL by inhibiting autophagy and up-regulating the protein levels of DR4/5 in colon cancer cells in vitro and in vivo.
Author: Qiao, Xinran|Wang, Xiaofei|Shang, Yue|Li, Yi|Chen, Shu-Zhen
PMID: 29970185
Journal: J Cell Biochem. 2018 Aug 30.
Title: Ferroptosis-inducing agents enhance TRAIL-induced apoptosis through upregulation of death receptor 5.
Author: Lee, Young-Sun|Lee, Dae-Hee|Jeong, So Yeon|Park, Seong Hye|Oh, Sang Cheul|Park, Yong Seok|Yu, Jian|Choudry, Haroon A|Bartlett, David L|Lee, Yong J
PMID: 30160785
Journal: Int J Oncol. 2018 Sep 14.
Title: Lipocalin 2 inversely regulates TRAIL sensitivity through p38 MAPK-mediated DR5 regulation in colorectal cancer.
Author: Kim, Se-Lim|Min, In Suk|Park, Young Ran|Lee, Soo Teik|Kim, Sang-Wook
PMID: 30221676